UNITED STATES
                         SECURITIES AND EXCHANGE COMMISSION
                               WASHINGTON, D.C. 20549



                                      FORM 10-K


  (Mark one)

  /X/ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
      EXCHANGE ACT OF 1934
      For the fiscal year ended December 31, 2001

      OR



  / / TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
      EXCHANGE ACT OF 1934


      Commission File Number:  333-48720-20


        Wells Fargo Asset Securities Corporation
        Mortgage Pass-Through Certificates
        Series 2001-21

       (Exact name of registrant as specified in its charter)



   New York                                       52-2350894
                                                  52-2350896
  (State or other jurisdiction of                 (I.R.S. Employer
  incorporation or organization)                  Identification No.)

   c/o Wells Fargo Bank Minnesota, N.A.
   11000 Broken Land Parkway
   Columbia, MD                                21044
  (Address of principal executive offices)     (Zip Code)


  Registrant's telephone number, including area code: (410) 884-2000


  Securities registered pursuant to Section 12(b) of the Act:

       NONE.



  Securities registered pursuant to Section 12(g) of the Act:

       NONE.



  Indicate by check mark whether the registrant (1) has filed all reports
  required to be filed by Section 13 or 15(d) of the Securities Exchange
  Act of 1934 during the preceding 12 months (or for such shorter period
  that the registrant was required to file such reports), and (2) has been
  subject to such filing requirements for the past 90 days.

      Yes  X       No ___







  Indicate by check mark if disclosure of delinquent filers pursuant to
  Item 405 of Regulation S-K ( 229.405 of this chapter) is not contained
  herein, and will not be contained, to the best of registrant's knowledge,
  in definitive proxy or information statements incorporated by reference
  in Part III of this Form 10-K or any amendment to this Form 10-K.

         Not applicable.






  State the aggregate market value of the voting and non-voting common
  equity held by non-affiliates of the registrant. The aggregate market
  value shall be computed by reference to the price at which the common
  equity was sold, or the average bid and asked prices of such common
  equity, as of a specified date within 60 days prior to the date of
  filing. (See definition of affiliate in Rule 405, 17 CFR 230.405.)

         Not applicable.








  Indicate the number of shares outstanding of each of the registrant's
  classes of common stock, as of the latest practicable date.

         Not applicable.



  List hereunder the following documents if incorporated by reference and
  the Part of the Form 10-K (e.g. Part I, Part II, etc..) into which the
  document is incorporated: (1)Any annual report to security holders; (2)
  Any proxy or information statement; and (3)Any prospectus filed pursuant
  to Rule 424(b) or (c) under the Securities Act of 1933. The listed
  documents should be clearly described for identification purposes (e.g.
  annual report to security holders for fiscal year ended December 24, 1980).

         Not applicable.










                                 PART I

  Item 1.  Business.

            Omitted.

  Item 2.  Properties.

            See Item 14(a), Exhibits 99.1, 99.2, and 99.3, for information
            provided in lieu of information required by Item 102 of
            Regulation S-K.



  Item 3.  Legal Proceedings.

            The registrant knows of no material pending legal proceedings
            involving the trusts created under the Pooling and Servicing
            Agreement (the Trusts), the Trustee, the Servicer or the
            registrant with respect to the Trusts other than routine
            litigation incidental to the duties of the respective parties.





  Item 4.  Submission of Matters to a Vote of Security Holders.


            None.

                               PART II


  Item 5.  Market for registrant's Common Equity and Related Stockholder
           Matters.


            No established public trading market for the Certificates exists.

            Records provided to the Trust by the DTC and the Trustee
            indicate that as of December 31, 2001, the number of holders of
            record for each class of Certificate were as follows:


             Class A-1                         1
             Class A-10                        1
             Class A-11                        2
             Class A-12                        1
             Class A-13                        1
             Class A-14                        1
             Class A-15                        2
             Class A-16                        1
             Class A-17                        2
             Class A-18                        6
             Class A-19                        1
             Class A-2                         2
             Class A-20                        1
             Class A-21                        1
             Class A-22                        2
             Class A-23                        1
             Class A-24                        2
             Class A-25                        3
             Class A-26                        2
             Class A-27                        2
             Class A-28                        3
             Class A-29                        1
             Class A-3                         1
             Class A-4                        21
             Class A-5                         2
             Class A-6                         3
             Class A-7                         2
             Class A-8                         1
             Class A-9                         1
             Class A-LR                        1
             Class A-PO                        1
             Class A-R                         1
             Class B-1                         2
             Class B-2                         1
             Class B-3                         2
             Class B-4                         1
             Class B-5                         1
             Class B-6                         1

             Total:                           81


  Item 6.  Selected Financial Data.

            Omitted.


  Item 7.  Management's Discussion and Analysis of Financial Condition and
           Results of Operation.

            Omitted.


  Item 7A. Quantitative and Qualitative Disclosures about Market Risk.

            Not applicable.

  Item 8.  Financial Statements and Supplementary Data.

            See Item 14(a), Exhibits 99.1, 99.2, 99.3, for information
            provided in lieu of information required by Item 302 of
            Regulation S-K.




  Item 9.  Changes in and Disagreements with Accountants on Accounting and
           Financial Disclosure.

            None.


                               PART III


  Item 10. Directors and Executive Officers of the Registrant.

            Not applicable.


  Item 11. Executive Compensation.

            Not applicable.


  Item 12. Security Ownership of Certain Beneficial Owners and Management.

            Not applicable.


  Item 13. Certain Relationships and Related Transactions.

            Not applicable.

                               PART IV


  Item 14. Exhibits, Financial Statement Schedules, and Reports on Form 8-K.

   (a) Exhibits

    (99.1) Annual Independent Accountants' Servicing Reports concerning
           servicing activities for the year ended December 31, 2001.




       a) Chevy Chase FSB, as Servicer <F1>
       b) Colonial Savings, F.A., as Servicer <F1>
       c) CUNA, as Servicer <F1>
       d) Hibernia National Bank, as Servicer <F1>
       e) Homeside Lending Inc (TX), as Servicer <F1>
       f) HSBC Bank, USA, as Servicer <F1>
       g) Mid America Bank, FSB, as Servicer <F1>
       h) National City Mortgage Co, as Servicer <F1>
       i) Sun Trust Mortgage Inc, as Servicer <F1>
       j) U.S. Bank Home Mortgage, as Servicer <F1>
       k) Wells Fargo Home Mortgage, Inc, as Servicer <F1>


    (99.2) Report of Management as to Compliance with Minimum Servicing
           Standards for the year ended December 31, 2001.




       a) Chevy Chase FSB, as Servicer <F1>
       b) Colonial Savings, F.A., as Servicer <F1>
       c) CUNA, as Servicer <F1>
       d) Hibernia National Bank, as Servicer <F1>
       e) Homeside Lending Inc (TX), as Servicer <F1>
       f) HSBC Bank, USA, as Servicer <F1>
       g) Mid America Bank, FSB, as Servicer <F1>
       h) National City Mortgage Co, as Servicer <F1>
       i) Sun Trust Mortgage Inc, as Servicer <F1>
       j) U.S. Bank Home Mortgage, as Servicer <F1>
       k) Wells Fargo Home Mortgage, Inc, as Servicer <F1>


    (99.3) Annual Statements of Compliance under the Pooling and Servicing
           Agreements for the year ended December 31, 2001.




       a) Chevy Chase FSB, as Servicer <F1>
       b) Colonial Savings, F.A., as Servicer <F1>
       c) CUNA, as Servicer <F1>
       d) Hibernia National Bank, as Servicer <F1>
       e) Homeside Lending Inc (TX), as Servicer <F1>
       f) HSBC Bank, USA, as Servicer <F1>
       g) Mid America Bank, FSB, as Servicer <F1>
       h) National City Mortgage Co, as Servicer <F1>
       i) Sun Trust Mortgage Inc, as Servicer <F1>
       j) U.S. Bank Home Mortgage, as Servicer <F1>
       k) Wells Fargo Home Mortgage, Inc, as Servicer <F1>



    (99.4) Aggregate Statement of Principal and Interest Distributions to
           Certificate Holders.


   (b)  On November 07, 2001, December 07, 2001, and January 10, 2002
        reports on Form 8-K were filed by the Company in order to provide
        the statements for the monthly distributions to holders of the
        Certificates. No other reports on Form 8-K have been filed during
        the last quarter of the period covered by this report.





   (c) Not applicable.


   (d) Omitted.

  <F1> Such document (i) is not filed herewith since such document was not
  received by the reporting person at least three business days prior to
  the due date covered by this report, and (ii) will be included in an
  amendment to this report on Form 10-K/A to be filed within 30 days of the
  Reporting Person's receipt of such document.






                               SIGNATURES


  Pursuant to the requirements of Section 13 or 15(d) of the Securities
  Exchange Act of 1934, the registrant has duly caused this report to be
  signed on its behalf by the undersigned, thereunto duly authorized:



    Wells Fargo Asset Securities Corporation
    Mortgage Pass-Through Certificates
    Series 2001-21
    (Registrant)



  Signed:  Wells Fargo Bank Minnesota, N.A., as Master Servicer


  By:   Beth Belfield, Officer

  By: /s/  Beth Belfield, Officer

  Dated: March 21, 2002

  SUPPLEMENTAL INFORMATION TO BE FURNISHED WITH REPORTS FILED PURSUANT TO
  SECTION 15(d) OF THE ACT BY REGISTRANTS WHICH HAVE NOT REGISTERED
  SECURITIES PURSUANT TO SECTION 12 OF THE ACT.



  (a)(i) No annual report is provided to the Certificateholders other than
  with respect to aggregate principal and interest distributions.


  (a)(ii) No proxy statement, form of proxy or other proxy soliciting
  material has been sent to any Certificateholder with respect to any
  annual or other meeting of Certificateholders.



  Ex-99.4
   Schedule of Year-To-Date Principal and Interest Distributions to
   Certificateholders


   <TABLE>

   Class                            Interest          Principal               Losses            Ending Balance
   
                      <c>                   <c>                 <c>                <c>
   A-1                         1,534,903.25        20,149,880.25                0.00            174,329,019.75
   A-10                           12,656.25                 0.00                0.00                750,000.00
   A-11                           12,656.25                 0.00                0.00                750,000.00
   A-12                           12,656.25                 0.00                0.00                750,000.00
   A-13                           12,656.25                 0.00                0.00                750,000.00
   A-14                           12,656.25                 0.00                0.00                750,000.00
   A-15                           12,656.25                 0.00                0.00                750,000.00
   A-16                           12,656.25                 0.00                0.00                750,000.00
   A-17                           42,187.50                 0.00                0.00              2,500,000.00
   A-18                        1,941,215.64                 0.00                0.00            115,035,000.00
   A-19                          448,875.00                 0.00                0.00             26,600,000.00
   A-2                         2,499,854.53                 0.00                0.00                      0.00
   A-20                           27,343.74                 0.00                0.00              1,750,000.00
   A-21                           28,437.51                 0.00                0.00              1,750,000.00
   A-22                           39,757.50                 0.00                0.00              2,356,000.00
   A-23                           30,624.99                 0.00                0.00              1,750,000.00
   A-24                           31,718.76                 0.00                0.00              1,750,000.00
   A-25                           32,499.99                 0.00                0.00              2,000,000.00
   A-26                           27,742.50                 0.00                0.00              1,644,000.00
   A-27                           35,000.01                 0.00                0.00              2,000,000.00
   A-28                          489,668.30           327,081.70                0.00             28,798,918.30
   A-29                          327,081.70          (327,081.70)               0.00             19,601,081.70
   A-3                           512,714.52         3,627,423.76                0.00             31,383,076.24
   A-4                         9,582,454.46        65,083,465.95                0.00            563,077,134.06
   A-5                            65,900.67           414,438.38                0.00              3,585,561.62
   A-6                           637,125.43          (637,125.43)               0.00             38,181,125.43
   A-7                            12,656.25                 0.00                0.00                750,000.00
   A-8                            12,656.25                 0.00                0.00                750,000.00
   A-9                            12,656.25                 0.00                0.00                750,000.00
   A-LR                                2.40                50.00                0.00                      0.00
   A-PO                                0.00            44,549.63                0.00              1,573,750.05
   A-R                                 0.28                50.00                0.00                      0.00
   B-1                           271,563.61            36,959.28                0.00             16,068,040.72
   B-2                           116,381.99            15,839.37                0.00              6,886,160.64
   B-3                            77,582.38            10,558.81                0.00              4,590,441.19
   B-4                            48,495.30             6,600.12                0.00              2,869,399.88
   B-5                            29,103.93             3,960.98                0.00              1,722,039.01
   B-6                            38,798.48             4,756.28              524.11              2,295,651.90
   </TABLE>