Exhibit 10.19

STOCK OPTION GRANT PROGRAM  FOR  NONEMPLOYEE DIRECTORS UNDER THE  NEORX CORPORATION RESTATED 1994 STOCK OPTION PLAN

The following provisions set forth the terms of the stock option grant program (the "Program") for nonemployee directors of NeoRx Corporation (the "Company")
under the Company's Restated 1994 Stock Option Plan (the "Plan"). The following terms are intended to supplement, not alter or change, the provisions of the Plan, and in the event of any inconsistency
between the terms contained herein and in the Plan, the Plan shall govern. All capitalized terms that are not defined herein shall be as defined in the Plan.

1.    Eligibility

Each
director of the Company elected or appointed to the Board who is not otherwise an employee of the Company or any Related Corporation (an "Eligible Director") shall be eligible to
receive New Grants and Annual Grants under the Plan, as discussed below.

2.    New Grants

Each
Eligible Director shall receive a nonqualified stock option to purchase 20,000 shares of Common Stock ("New Grant") upon such Eligible Director's initial election or appointment to
the Board. New Grants shall vest and become exercisable in two equal installments according to the schedule set forth in Section 4 below.

3.    Annual Grants

Each
Eligible Director shall automatically receive a nonqualified stock option to purchase 10,000 shares of Common Stock immediately following each year's annual meeting of shareholders
(each, an "Annual
Grant"); provided that any Eligible Director who received a New Grant within five months prior to an annual meeting of shareholders shall not receive an Annual Grant until the next year's annual
meeting. Annual Grants shall vest and become exercisable in two equal installments according to the schedule set forth in Section 4.

4.    Vesting and Exercisability

Options
shall vest and become exercisable according to the following schedule:



Period of Optionee's Continuous
Service as an Eligible Director From
the Date the Option Is Granted

Portion of Grant
That Is Vested and ExercisableOne year

50%Two years

100%




Period of Optionee's Continuous
Service as an Eligible Director From
the Date the Option Is Granted

Portion of Grant
That Is Vested and ExercisableUpon first annual meeting of shareholders after grant

50%Upon second annual meeting of shareholders after grant

100%


Subject
to the exercisability schedule described above, each option may be exercised in whole or in part at any time.

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5.    Option Exercise Price

The
exercise price of an option shall be the fair market value of the Common Stock on the date of grant.

6.    Manner of Option Exercise

An
option shall be exercised by giving the required notice to the Company, stating the number of shares of Common Stock with respect to which the option is being exercised, accompanied
by payment in full for such Common Stock, which payment may be in whole or in part (a) in cash or check, (b) in shares of Common Stock owned by the Eligible Director for at least six
months (or any shorter period necessary to avoid a charge to the Company's earnings for financial reporting purposes) having a fair market value equal to the aggregate option exercise price, or
(c) if and so long as the Common Stock is registered under the Exchange Act, by delivery of a properly executed exercise notice, together with irrevocable instructions to a broker, to promptly
deliver to the Company the amount of sale or loan proceeds to pay the exercise price, all in accordance with the regulations of the Federal Reserve Board.

7.    Term of Options

Each
option shall expire upon the earlier of ten years from the date of grant or five years after an Eligible Director's termination of service as a director, as follows:



8.    Transferability

During
an Eligible Director's lifetime, an option may be exercised only by the Eligible Director or a permitted assignee or transferee of the Eligible Director (as provided below). No
options granted under the Program may be assigned, pledged or transferred by the Eligible Director other than by (a) will or the applicable laws of descent and distribution, (b) gift or
other transfer to either (i) a spouse or other immediate family member or (ii) any trust, partnership or other entity in which the Eligible Director or such Eligible Director's spouse or
other immediate family member has a substantial beneficial interest; or (c) the designation by an Eligible Director in writing during the Eligible Director's lifetime of a beneficiary to
receive and exercise options in the event of the Eligible Director's death (as provided in Section 5 of the Plan); provided, however, that any option so assigned or transferred shall be subject
to all the same terms and conditions contained in the instrument evidencing the option. Any attempt to transfer, assign, pledge, hypothecate or otherwise dispose of any option under the Plan or of any
right or privilege conferred thereby, contrary to the provisions of the Plan, or the sale or levy or any attachment or similar process upon the rights and privileges conferred hereby, shall be null
and void.

9.    Amendment

The
Board may amend the provisions contained herein in such respects as it deems advisable. Any such amendment shall not, without the consent of the Eligible Director, impair or diminish
any rights of an Eligible Director or any rights of the Company under an option.

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10.    Effective Date

The
Program shall become effective on the date approved by the Company's Board of Directors. Provisions of the Plan (including any amendments) that were not discussed above, to the
extent applicable to Eligible Directors, shall continue to govern the terms and conditions of options granted to Eligible Directors.

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