1 **Prometon Fo**  **cus Meeting**  **Summary November 7**  **, 2012 1:00** 

**– 2:00**  **pm A**  **ttendees MANA**  **:** Kristen Knox and (via conference line) Elliot Gordon **Control Solutions, Inc.** (via conference line) : Anne Turnbough **Environmental Protection Agency (EPA or Agency) :**  Kaitlin Keller (PRD), Tracy Perry (PRD), William Irwin (HED) , Robin Sternberg (EFED), Steve Wente (EFED), Sujatha Sankula (EFED), Cy

nthia Doucoure (BEAD), John Faulkner (BEAD) **Objective** The purpose of the meeting was for members of the EPA ’s Pesticide Re

- evaluat ion Division (PRD) , Environmental F ate and Effects Division (EFED) , Biological and Economic Anal ys is Division (BEAD), and Health Effects Division (HED) to meet with Mahkteshim Agan of North America (MANA), the technical registrant for prometon , for the f ollowing reasons: 1) discuss us age information needed for the reg istration review ecological risk assessment s , and 2) discuss anticipated ecotoxicity

and environmental fate data requirements and information that could be submitted to fulfill these data gap s. **Discussion** Use/Usage Information CSI provided usage information in terms of amounts used in pounds per y ear, noting that this information can be broken down by product and will be submitted to the Agency via email with a complete summary

of labels an d use sites

. MANA confirmed that all residential use products have been cancelled, as required b y the Reregistration Eligibility Decision (RED). EPA has already received a FIFRA 6(f) request to cancel all residential uses of prometon on October 3, 2012, which will be published with a 30

- day comment period in the Federal Register in FY 2013 Q1. EPA requested additional information on ty pical rates for each use scenario and the size of a ty pical spot treatment along various use sites, such as highway median s, fencerows, and airports. EPA noted that this information could help reduce conservatisms in the ecological risk assessments. Environmental Fate and Effects Information EPA requested additional information on the degradates of prometon, specifically how long they take to break down and any toxicity effects in the environment and/or an y l aboratory studies using rats. MANA committed to reviewing their database and providing any information within three weeks of the meeting date. EPA also presented a l ist of anticipated data gaps and explained that some conservative methods, such as the acute

- to
- chronic ratio, could be used to account for the lack of several of the data gaps. MANA stated that European Union (EU) data is not available for this chemical and all2

studies were already submitted before the RED was completed. EPA suggested reviewing open literature and their database for information on other triazine herbicides, such as atrazine and simazine, for information which may be useful. EPA agreed to review and consider an y proposals or waiver requests based on a rationale of low toxicity and/or bridging data used for other triazine class herbicides. EPA requested any water monitoring data available. MANA was not aware of this information but agre ed to submit any water monitoring data that they may find. **Follow -**  **up**

 EPA will inform MANA when the 6(f) voluntary cancellation reques t for all prometon residential uses publishes in the Federal Register.
 MANA and CSI will submit use/usage and market shar e information, as well as ty pical use rates and size of t ypi cal spot treatments.
 M ANA will review their scientific database and open literature sources for information th at could fulfill current data gaps and respond to EPA with this information within thr ee weeks.