Exhibit 21

NOVAMED, INC. SUBSIDIARIES

|1.  |  | NovaMed Management of Kansas City, Inc., a Missouri corporation                          
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|2.  |  | Blue Ridge NovaMed, Inc., a Missouri corporation                                         
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|3.  |  | NovaMed Eye Surgery Center (Plaza) L.L.C., a Delaware limited liability company          
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|4.  |  | NovaMed Eye Surgery Center of Overland Park, L.L.C., a Delaware limited liability company
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|5.  |  | NovaMed Management Services, LLC, a Delaware limited liability company                   
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|6.  |  | NovaMed Eye Surgery Center of Maryville, L.L.C., a Delaware limited liability company    
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|7.  |  | NovaMed Eye Surgery Center of North County, LLC, a Delaware limited liability company    
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|8.  |  | NovaMed Eye Surgery Center of New Albany, L.L.C., a Delaware limited liability company   
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|9.  |  | NovaMed of Louisville, Inc., a Kentucky corporation                                      
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|10. |  | Midwest Uncuts, Inc., an Iowa corporation                                                
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|11. |  | NovaMed Eyecare Research, Inc., a Delaware corporation                                   
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|12. |  | NovaMed Eye Surgery and Laser Center of St. Joseph, Inc., a Missouri corporation         
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|13. |  | NMGK, Inc., an Illinois corporation                                                      
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|14. |  | NMLO, Inc., a Kansas corporation                                                         
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|15. |  | NovaMed Eye Surgery Center of Cincinnati, LLC, a Delaware limited liability company      
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|16. |  | Patient Education Concepts, Inc., a Delaware corporation                                 
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|17. |  | NMI, Inc., a Georgia corporation                                                         
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|18. |  | NovaMed Acquisition Company, Inc., a Delaware corporation                                
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|19. |  | NovaMed Surgery Center of Thibodaux, LLC, a Delaware limited liability company           
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|20. |  | NovaMed Surgery Center of Richmond, LLC, a Delaware limited liability company            
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|21. |  | NovaMed Surgery Center of River Forest, LLC, a Delaware limited liability company        
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|22. |  | NovaMed Surgery Center of Colorado Springs, LLC, a Delaware limited liability company    
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|23. |  | NovaMed of Texas, Inc., a Delaware corporation                                           
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|24. |  | NovaMed Surgery Center of Tyler, L.P., a Delaware limited partnership                    
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|25. |  | NovaMed Alliance, Inc., a Delaware corporation                                           
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|26. |  | NovaMed Surgery Center of Merrillville, LLC, a Delaware limited liability company        
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|27. |  | NovaMed Surgery Center of Chicago - Northshore, LLC, a Delaware limited liability company
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|28. |  | NovaMed Surgery Center of Columbus, LLC, a Delaware limited liability company            
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|29. |  | Blue Ridge Surgical Center, LLC, a Delaware limited liability company                    
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|30. |  | NovaMed Surgery Center of Chattanooga, LLC, a Delaware limited liability company         
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|31. |  | NovaMed Surgery Center of Nashua, LLC, a Delaware limited liability company              
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|32. |  | NovaMed Surgery Center of Bedford, LLC, a Delaware limited liability company             
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|33. |  | NovaMed Surgery Center of Altamonte Springs, LLC, a Delaware limited liability company   
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|34. |  | NovaMed Surgery Center of Oak Lawn, LLC, a Delaware limited liability company            
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|35. |  | NovaMed Surgery Center of Palm Beach, LLC, a Delaware limited liability company          
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|36. |  | NovaMed Surgery Center of Fort Lauderdale, LLC, a Delaware limited liability company     
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|37. |  | NovaMed Surgery Center of Madison, Limited Partnership, a Wisconsin limited partnership  
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|38. |  | NovaMed of Wisconsin, Inc., a Delaware corporation                                       
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|39. |  | NovaMed Pain Management Center of New Albany, LLC, a Delaware limited liability company  
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|40. |  | The Cataract Specialty Surgical Center, L.L.C., a Michigan limited liability company     
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|41. |  | NovaMed Surgery Center of Denver, LLC, a Delaware limited liability company              
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|42. |  | NovaMed Surgery Center of Whittier, LLC, a Delaware limited liability company            
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|43. |  | Surgery Center of Fremont, LLC, a Delaware limited liability company                     
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|44. |  | NovaMed of Dallas, Inc., a Delaware corporation                                          
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|45. |  | NovaMed Surgery Center of Dallas, LP, a Delaware limited partnership                     
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|46. |  | NovaMed of San Antonio, Inc., a Delaware corporation                                     
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|47. |  | NovaMed Surgery Center of San Antonio, LP, a Delaware limited partnership                
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|48. |  | NovaMed Surgery Center of Jonesboro, LLC, a Delaware limited liability company           
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|49. |  | NovaMed Surgery Center of Laredo, LP, a Delaware limited partnership                     
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|50. |  | NovaMed of Laredo, Inc., a Delaware corporation                                          
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|51. |  | NovaMed Surgery Center of Sandusky, LLC, a Delaware limited liability company   
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|52. |  | Laser and Outpatient Surgery Center, LLC, a Delaware limited liability company  
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|53. |  | NovaMed Surgery Center of Cleveland, LLC, a Delaware limited liability company  
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|54. |  | NovaMed Surgery Center of Warrensburg, LLC, a Delaware limited liability company
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|55. |  | NovaMed Surgery Center of Sebring, LLC, a Delaware limited liability company    
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|56. |  | NovaMed Surgery Center of St. Peters, LLC, a Delaware limited liability company 
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