Exhibit
21

NOVAMED, INC.
SUBSIDIARIES

|1.  |  | NovaMed Management of Kansas
      City, Inc., a Missouri corporation                          
|--- |  | -----------------------------------------------------------------------------------------------
|   
|2.  |  | Blue Ridge NovaMed, Inc., a
      Missouri corporation                                         
|   
|3.  |  | NovaMed Eye Surgery Center
      (Plaza) L.L.C., a Delaware limited liability company          
|   
|4.  |  | NovaMed Eye Surgery Center of
      Overland Park, L.L.C., a Delaware limited liability company
|   
|5.  |  | NovaMed Management Services, LLC,
      a Delaware limited liability company                   
|   
|6.  |  | NovaMed Eye Surgery Center of
      Maryville, L.L.C., a Delaware limited liability company    
|   
|7.  |  | NovaMed Eye Surgery Center of
      North County, LLC, a Delaware limited liability company    
|   
|8.  |  | NovaMed Eye Surgery Center of New
      Albany, L.L.C., a Delaware limited liability company   
|   
|9.  |  | NovaMed of Louisville, Inc., a
      Kentucky corporation                                      
|   
|10. |  | Midwest Uncuts, Inc., an Iowa
      corporation                                                
|   
|11. |  | NovaMed Eyecare Research, Inc., a
      Delaware corporation                                   
|   
|12. |  | NovaMed Eye Surgery and Laser
      Center of St. Joseph, Inc., a Missouri corporation         
|   
|13. |  | NMGK, Inc., an Illinois
      corporation                                                      
|   
|14. |  | NMLO, Inc., a Kansas
      corporation                                                         
|   
|15. |  | NovaMed Eye Surgery Center of
      Cincinnati, LLC, a Delaware limited liability company      
|   
|16. |  | Patient Education Concepts, Inc.,
      a Delaware corporation                                 
|   
|17. |  | NMI, Inc., a Georgia
      corporation                                                         
|   
|18. |  | NovaMed Acquisition Company,
      Inc., a Delaware corporation                                
|   
|19. |  | NovaMed Surgery Center of
      Thibodaux, LLC, a Delaware limited liability company           
|   
|20. |  | NovaMed Surgery Center of
      Richmond, LLC, a Delaware limited liability company            
|   
|21. |  | NovaMed Surgery Center of River
      Forest, LLC, a Delaware limited liability company        
|   
|22. |  | NovaMed Surgery Center of
      Colorado Springs, LLC, a Delaware limited liability company    
|   
|23. |  | NovaMed of Texas, Inc., a
      Delaware corporation                                           
|   
|24. |  | NovaMed Surgery Center of Tyler,
      L.P., a Delaware limited partnership                    
|   

---

|25. |  | NovaMed Alliance, Inc., a
      Delaware corporation                                           
|--- |  | -----------------------------------------------------------------------------------------------
|   
|26. |  | NovaMed Surgery Center of
      Merrillville, LLC, a Delaware limited liability company        
|   
|27. |  | NovaMed Surgery Center of Chicago
      - Northshore, LLC, a Delaware limited liability company
|   
|28. |  | NovaMed Surgery Center of
      Columbus, LLC, a Delaware limited liability company            
|   
|29. |  | Blue Ridge Surgical Center, LLC,
      a Delaware limited liability company                    
|   
|30. |  | NovaMed Surgery Center of
      Chattanooga, LLC, a Delaware limited liability company         
|   
|31. |  | NovaMed Surgery Center of Nashua,
      LLC, a Delaware limited liability company              
|   
|32. |  | NovaMed Surgery Center of
      Bedford, LLC, a Delaware limited liability company             
|   
|33. |  | NovaMed Surgery Center of
      Altamonte Springs, LLC, a Delaware limited liability company   
|   
|34. |  | NovaMed Surgery Center of Oak
      Lawn, LLC, a Delaware limited liability company            
|   
|35. |  | NovaMed Surgery Center of Palm
      Beach, LLC, a Delaware limited liability company          
|   
|36. |  | NovaMed Surgery Center of Fort
      Lauderdale, LLC, a Delaware limited liability company     
|   
|37. |  | NovaMed Surgery Center of
      Madison, Limited Partnership, a Wisconsin limited partnership  
|   
|38. |  | NovaMed of Wisconsin, Inc., a
      Delaware corporation                                       
|   
|39. |  | NovaMed Pain Management Center of
      New Albany, LLC, a Delaware limited liability company  
|   
|40. |  | The Cataract Specialty Surgical
      Center, L.L.C., a Michigan limited liability company     
|   
|41. |  | NovaMed Surgery Center of Denver,
      LLC, a Delaware limited liability company              
|   
|42. |  | NovaMed Surgery Center of
      Whittier, LLC, a Delaware limited liability company            
|   
|43. |  | Surgery Center of Fremont, LLC, a
      Delaware limited liability company                     
|   
|44. |  | NovaMed of Dallas, Inc., a
      Delaware corporation                                          
|   
|45. |  | NovaMed Surgery Center of Dallas,
      LP, a Delaware limited partnership                     
|   
|46. |  | NovaMed of San Antonio, Inc., a
      Delaware corporation                                     
|    |  |                                                                                                
|47. |  | NovaMed Surgery Center of San
      Antonio, LP, a Delaware limited partnership                
|   

---