**Exhibit      10.1**

**SUMMARY      OF KEY TERMS OF COMPENSATION ARRANGEMENTS WITH SYNTHETECH, INC. EXECUTIVE      OFFICERS**

|                                                                                                                               |   |                         |    |                                                                                         |                          | **Fiscal                2008 Target Bonus Allocation**          |   |
|------------------------------------------------------------------------------------------------------------------------------------|--------|------------------------------|---------|---------------------------------------------------------------------------------------------------|-------------------------------|-----------------------------------------------------------------|--------|
| **Name                and Title**                                                                                                  |   | **Fiscal****2008****Salary** |    | **Fiscal                2008 Range of****Cash****Incentive                as a % of Base Salary** |                          | **Health,                Safety and Environ-mental Objectives** |   |   | **Business                Strategy Objectives** |   |   | **Business                Performance Objectives** |   |
| Dr.                Daniel T. FaganChief                Executive Officer                                                           |   | $                            | 150,000 |                                                                                              | 0                to 77%  |                                                            |   | 10% |   |   |   | 30% |   |   |   | 60% |   |
| Dr.                Gregory R. HahnPresident                and Chief Operating Officer                                             |   | $                            | 200,000 |                                                                                              | 0                to 81%  |                                                            |   | 10% |   |   |   | 10% |   |   |   | 80% |   |
| Gary                A. WeberVice                President of Finance and Administration and Chief Financial                Officer |   | $                            | 145,000 |                                                                                              | 0                to 57%  |                                                            |   | 10% |   |   |   | 25% |   |   |   | 65% |   |
| Joel                D. Melka2Vice                President of Operations                                                           |   | $                            | 140,000 |                                                                                              | 0                to 45%  |                                                            |   | 15% |   |   |   | 35% |   |   |   | 50% |   |

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| **Health,                Safety and Environmental Objectives:** |                                                                      | **10-15%**                                                                                               |
|-----------------------------------------------------------------|---------------------------------------------------------------------------|----------------------------------------------------------------------------------------------------------|
|                                                            |                                                                      |                                                                                                     |   |
|                                                            | *Recordable                Injuries*                                      | *4-5%                *   |   |
|                                                            | *Lost-Time                Accidents*                                      | *4-5%                *   |   |
|                                                            | *Process                Safety and Reportable Environmental Incident*     | *2-5%                *   |   |
|                                                            |                                                                      |                                                                                                     |   |
| **Business                Strategy Objectives:**                |                                                                      | **10-35%**                                                                                               |
|                                                            | *New                Technology*                                           | *10%                *    |   |
|                                                            | *New                Business Areas*                                       | *5%                *     |   |
|                                                            | *Cost                Controls and Improvements*                           | *10-20%                * |   |
|                                                            | *Process                Development*                                      | *5%                *     |   |
|                                                            | *Sarbanes-Oxley 404                Analysis*                         | *5-10%                *  |   |
|                                                            | *Investor                Relations*                                       | *5%                *     |   |
|                                                            | *ISO                14001 Certification*                                  | *5%                *     |   |
|                                                            |                                                                      |                                                                                                     |   |
| **Business                Performance Objectives:**             |                                                                      | **50-80%**                                                                                               |
|                                                            |                                                                      |                                                                                                     |   |
|                                                            | *Achieve                Sales Target*                                     | *10-20%                * |   |
|                                                            | *Achieve                EBIT (earnings before interest and taxes) Target* | *40-60%                * |   |