# Registration Notice Conditional v.20150320 

# U.S. ENVIRONMENTAL PROTECTION AGENCY

Office of Pesticide Programs

Registration Division (7505P)

1200 Pennsylvania Ave., N.W.

Washington, D.C. 20460 EPA Reg. Number:



# 71512-22 Date of Issuance:



# 7/21/15

NOTICE OF PESTICIDE:

X Registration

Reregistration Term of Issuance:



# Conditional

(under FIFRA, as amended)

Name of Pesticide Product:



# Isofetamid 400SC Fungicide

Name and Address of Registrant (include ZIP Code):



# Michael Peplowski

ISK Biosciences Corporation

7470 Auburn Road, Suite A

Concord, OH 44077

Note: Changes in labeling differing in substance from that accepted in connection with this registration must be submitted to and ac cepted by the

Registration Division prior to use of the label in commerce. In any correspondence on this product always refer to the above E PA registration number.



# On the basis of information furnished by the registra nt, the above named pesticide is hereby registered

under the Federal Insecticide, Fungicide and Rodenticide Act.

Registration is in no way to be construed as an en dorsement or recommendation of this product by the

Agency. In order to protect health and the enviro nment, the Administrator, on his motion, may at any

time suspend or cancel the registration of a pesticid e in accordance with the Act. The acceptance of any

name in connection with the registration of a product under this Act is not to be construed as giving the

registrant a right to exclusive use of the name or to its use if it has been covered by others.

This product is conditionally registered in accordance with FIFRA section 3(c)(7)(C). You must comply

with the following conditions:

1. Submit and/or cite all data requ ired for registration/reregistra tion/registration review of your

product under FIFRA when the Agency requires all registrants of similar products to submit such

data.

Signature of Approving Official:



# Tony Kish, Product Manager 22

Fungicide Branch, Registration Division (7505P) Date:



# 7/21/15

EPA Form 8570-6

# Page 2 of 2

EPA Reg. No. 71512-22

Decision No. 474286

2. You are required to submit to the Agency the follo wing three studies: acute oral toxicity to larval

honey bees; chronic oral toxicity to larval honey bees; and chroni c oral toxicity to adult honey

bees. Protocols for each of the chronic studies are required prior to ini tiating the studies. The

protocols are due 3 months from the date of th is Registration Notice. The studies are due 12

months from the date of this Registration No tice. Thus, the 12 months includes submission and

review of both the protocols and data. Your failure to provide these data in a timely or adequate

manner may result in initiation of a cancel lation action against your registration.

3. Make the following label change before you release the product for shipment:

 Revise the EPA Registration Number to read, “EPA Reg. No. 71512-22.”

4. Submit one copy of the final printed label for the record before you release the product for

shipment.

Should you wish to add/retain a reference to the comp any’s website on your label, then please be aware

that the website becomes labeling under the Federal Insec ticide Fungicide and Rodenticide Act and is

subject to review by the Agency. If the website is false or mislead ing, the product would be misbranded

and unlawful to sell or distribu te under FIFRA section 12(a)(1)(E ). 40 CFR 156.10(a)(5) list examples

of statements EPA may consider false or misleading. In addition, re gardless of whether a website is

referenced on your product’s label, claims made on the website may not substantially differ from those

claims approved through the registration process. Ther efore, should the Agency fi nd or if it is brought to

our attention that a website contains false or mislea ding statements or claims substantially differing from

the EPA approved registration, the website will be re ferred to the EPA’s Office of Enforcement and

Compliance.

If you fail to satisfy these data requirements, EPA will consider appropriate regulatory action including,

among other things, cancellation under FIFRA section 6(e). Your release for shipment of the product

constitutes acceptance of these cond itions. A stamped copy of the label is enclosed for your records.

Please also note that the record for this product currently contai ns the following CSF:

 Basic CSF dated 12/14/2012

If you have any questions, please contact Heathe r Garvie by phone at 703-308-0034, or via email at

garvie.heather@epa.gov.

EnclosurePage 1FIRST AIDIf swallowedxCall a poison control center or doctor immediatelyfor treatment advice.xHave person sip a glass of water if able to swallow.xDo not induce vomiting unless told to do so by apoison control center or doctor.xDo not give anything to an unconscious person.If on skinxTake off contaminated clothing.xRinse skin immediately with plenty of soap andwater for 15-20 minutes.xCall a poison control center or doctor for treatmentadvice.Have the product container or label with you when calling a poison controlcenter or doctor, or going for treatment.HOT LINE NUMBERFor24-Hour Medical Emergency Assistance(Human or Animal)Call1-888-484-7546.ForChemical Emergency, Spill, Leak, Fire or Accident, CallCHEMTREC 1-800-424-9300.ISOFETAMID 400SCFUNGICIDEACTIVE INGREDIENT: Isofetamid* ................................... 36.0%OTHER INGREDIENTS: ...................................................... 64.0%Total...................................................................................... 100.0%*N-[1,1-dimethyl-2-[2-methyl-4-(1-methylethoxy)phenyl]-2-oxoethyl]-3-methyl-2-thiophenecarboxamideContains 3.33 pounds IsofetamidPer Gallon (400 grams per liter)KEEP OUT OF REACH OF CHILDRENCAUTIONSee side panel for additional precautionary statements.Read entire label carefully and use only as directed.ISK Biosciences Corporation7470 Auburn Road, Suite AConcord, Ohio 44077 U.S.A.EPA Reg. No. 71512-EE EPA Est. No.Active Ingredient Made in JapanFormulated inNet Contents:GROUP 7 FUNGICIDE07/21/201571512-22Page 2PRECAUTIONARY STATEMENTSHAZARDS TO HUMANS AND DOMESTIC ANIMALSCAUTIONHarmful if swallowed or absorbed through skin. Avoid contact with skin,eyes or clothing. Wash thoroughly with soap and water after handling andbefore eating, drinking, chewing gum, using tobacco or using the toilet.Remove and wash contaminated clothing before reuse.Personal Protective Equipment (PPE)Applicators and other handlers must wear long-sleeved shirt and long pants,socks, shoes, and chemical resistant gloves made of any waterproofmaterial.Follow manufacturer’s instructions for cleaning/ maintaining PPE. If nosuch instructions for washables, use detergent and hot water. Keep and washPPE separately from other laundry.Engineering Control StatementsWhen handlers use closed systems, enclosed cabs, or aircraft in a mannerthat meets the requirements listed in the Worker Protection Standard (WPS)for agricultural pesticides [40 CFR 170.240(d)(4-6)], the handler PPErequirements may be reduced or modified as specified in the WPS.User Safety RecommendationsUsers should:xWash hands before eating, drinking, chewing gum, using tobacco orusing the toilet.xRemove clothing/PPE immediately if pesticide gets inside. Then washthoroughly and put on clean clothing.xRemove PPE immediately after handling this product. Wash the outsideof gloves before removing. As soon as possible, wash thoroughly andchange into clean clothing.ENVIRONMENTAL HAZARDSThis pesticide is toxic to oysters. DO NOT apply directly to water, or toareas where surface water is present or to intertidal areas below the meanhigh water mark. DO NOT contaminate waters when disposing ofequipment washwaters or rinsate. Donot apply when weather conditionsfavor drift from the treated areas. Drift and runoff may be hazardous toaquatic organisms in water adjacent to treated areas.AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THERESPONSIBILITY OF THE APPLICATOR. The interaction of manyequipment-and-weather-related factors determine the potential for spraydrift. The applicator is responsible for considering all these factors whenmaking decisions. Where states have more stringent regulations, theymust be observed.STORAGE AND DISPOSALDO NOT contaminate water, food or feed by storage or disposal.PESTICIDE STORAGE:Store in original container, in a secured, dry,cool place separate from fertilizer, food, and feed. Avoid crosscontamination with other pesticides.PESTICIDE DISPOSAL:Pesticide wastes may be hazardous.Improper disposal of excess pesticide, spray mixture or rinsate is aviolation of Federal law. If these wastes cannot be disposed of by useaccording to label instructions, contact your State Pesticide orEnvironmental Control Agency or the Hazardous Waste representative atthe nearest EPA Regional Office for guidance.CONTAINER HANDLING:Nonrefillable container (equal to or lessthan 5 gallons). DO NOT reuse or refill this container. Triple rinsecontainer (or equivalent) promptly after emptying. Triple rinse asfollows: Empty the remaining contents into application equipment or amix tank and drain for 10 seconds after the flow begins to drip. Fill thecontainer 1⁄4 full with water and recap. Shake for 10 seconds. Pour rinsateinto application equipment or a mix tank or store rinsate for later use ordisposal. Drain for 10 seconds after the flow begins to drip. Repeat thisprocedure two more times. Then offer for recycling if available, orpuncture and dispose of in a sanitary landfill, or by incineration or, ifallowed by state and local authorities, by burning. If burned, stay out ofsmoke.Nonrefillable container (greater than 5 gallons). DO NOT reuse or refillthis container. Triple rinse container (or equivalent) promptly afteremptying. Triple rinse as follows: Empty the remaining contents intoapplication equipment or a mix tank. Fill the container 1⁄4 full with water.Recap and tighten closures. Tip container on its side and roll it back andforth, ensuring at least one complete revolution, for 30 seconds. Stand thecontainer on its end and tip it back and forth several times. Turn thecontainer over onto its other end and tip it back and forth several times.Empty rinsate into application equipment or a mix tank or store rinsate forlater use or disposal. Repeat this procedure two more times. Then offerfor recycling if available, or puncture and dispose of in a sanitary landfill,Page 3or by incineration or, if allowed by state and local authorities, by burning.If burned, stay out of smoke.DIRECTIONS FOR USEIt is a violation of Federal law to use this product in a manner inconsistentwith its labeling.DO NOT apply this product in a way that will contact workers or otherpersons, either directly or through drift. Only protected handlers may be inthe area during application. For any requirements specific to your State orTribe, consult the agency responsible for pesticide regulation.AGRICULTURAL USE REQUIREMENTSUse this product only in accordance with its labeling and with the WorkerProtection Standard, 40 CFR Part170. This Standard containsrequirements for the protection of agricultural workers on farms, forests,nurseries, and greenhouses and handlers of agricultural pesticides. Itcontains requirements for training, decontamination, notification, andemergency assistance. It also contains specific instructions and exceptionspertaining to the statements on this label about personal protectiveequipment (PPE), and restricted-entry interval. The requirements in thisbox only apply to uses of this product that are covered by the WorkerProtection Standard.DO NOT enter or allow worker entry into treated areas during the restrictedentry interval (REI) of twelve (12) hours.PPE required for early entry into treated areas that is permitted under theWorker Protection Standard and that involves contact with anything thathas been treated, such as plants, soil, or water, is: coveralls, chemicalresistant gloves made of any waterproof material, shoes plus socks.FAILURE TO FOLLOW THE USE DIRECTIONS ANDPRECAUTIONS ON THIS LABEL MAY RESULT IN PLANT INJURYOR POOR DISEASE CONTROL.PRODUCT INFORMATIONISOFETAMID is a broad-spectrum fungicide with preventative, systemicand curative properties for foliar and soil-borne diseases. ISOFETAMIDmust be applied in scheduled protective programs and used in rotation withproducts with a different mode of action.MIXING AND SPRAYINGISOFETAMID 400SC can be used effectively in dilute or concentratesprays. Thorough, uniform coverage is essential for disease control.NOTE: Slowly invert container several times to assure uniform mixture offormulation before adding this product to the spray tank.Dosage rates on this label indicate fluid ounces of ISOFETAMID 400SCper acre, unless otherwise stated. Under conditions highly favorable fordisease development, the highest rate specified and shortest applicationinterval should be used.ISOFETAMID 400SC may be applied with all types of spray equipmentnormally used for ground, chemigation through sprinkler irrigation andaerial applications.The required amount of ISOFETAMID 400SC should be added slowlyinto the spray tank during filling. With concentrate sprays, pre-mix therequired amount of ISOFETAMID 400SC in a clean container and add tothe spray tank as it is being filled. Keep agitator running when fillingspray tank and during spray operations. DO NOT allow spray mixture tostand overnight or for prolonged periods. Prepare only the amount ofspray required for immediate use. Spraying equipment should bethoroughly cleaned immediately after the application.Apply ISOFETAMID 400SC in sufficient water to obtain adequatecoverage of the foliage. Gallonage to be used will vary with crop andamount of plant growth. Spray volume will usually range from 20 to 100gallons per acre (200 to 1000 liters per hectare) for dilute sprays, and 5 to10 gallons per acre (50 to 100 liters per hectare) for concentrate groundand aerial sprays. For aerial applications, apply ISOFETAMID 400SC ina minimum of 5 gallons of water per acre. For application throughsprinkler irrigation systems see application and calibration instructionsbelow.TANK MIX COMPATIBILITYISOFETAMID 400SC is physically compatible (no nozzle or screenblockage) with many products labeled for control of diseases and insectson crops and other additives. Read and follow all manufacturer's labelprecautions and restrictions for the tank mix companion product. It is theapplicator’s responsibility to ensure that the companion product is EPAapproved for use on the intended crop. ISOFETAMID 400SC is generallyPage 4compatible with other insecticides, fungicides, adjuvants, fertilizers andmicronutrient products provided sufficient free water is available fordispersion of all the tank mix products. Under some conditions, the use ofadjuvants and surfactants at the rate of 0.025% to 0.1% of the spray tankvolume may improve the performance of ISOFETAMID 400SC.However, not all crop varieties have been tested with all possible tank mixcombinations. Thus the combination should be tested for crop safety on asmall portion of the crop to ensure that a phytotoxic response will notoccur. In addition, the physical compatibility of ISOFETMAID 400SCwith tank mix partners must be evaluated before use. Conduct a jar testwith intended tank-mix pesticides prior to preparation of large volumes.Use the following procedure: 1) Pour the recommended proportions of theproducts into a suitable container of water, 2) Mix thoroughly and 3)Allow to stand for 5 minutes. If the combination remains mixed or can bere-mixed readily, it is considered physically compatible. Any physicalincompatibility in the jar test indicates that ISOFETAMID 400SC shouldnot be used in the tank-mix.ROTATIONAL CROP RESTRICTIONSCrops on this label may be planted immediately after the last treatment.Do not plant other crops not registered for this product within 30 daysafter the last application.INTEGRATED PEST MANAGEMENTISOFETAMID 400SC is an excellent disease control agent when usedaccording to label directions for control of labeled fungi. ISOFETAMID400SC is recommended for use as part of an Integrated Pest Management(IPM) program, which may include the use of disease-resistant cropvarieties, cultural practices, crop rotation, biological disease controlagents, pest scouting and disease forecasting systems aimed at preventingeconomic pest damage. Practices known to reduce disease developmentshould be followed. Consult your state cooperative extension service orlocal agricultural authorities for additional IPM strategies established inyour area. ISOFETAMID 400SC maybe used in State AgriculturalExtension advisory (disease forecasting) programs that recommendapplication timing based upon environmental factors that favor diseasedevelopment.RESISTANCE MANAGEMENTSome plant pathogens are known to develop resistance to products usedrepeatedly for disease control. ISOFETAMID 400SC’s mode/target siteof action is complex II; succinate-dehydrogenase, FRAC Group 7. Adisease management program that includes alternation or tank mixesbetween ISOFETAMID 400SC and other labeled fungicides that have adifferent mode of action and/or control pathogens not controlled withISOFETAMID 400SC is essential to prevent disease resistant pathogenspopulations from developing.ISOFETAMID 400SC should not beutilized continuously nor tank mixed with fungicides that have shown tohave developed fungal resistance to the target disease.Since pathogens differ in their potential to develop resistance tofungicides, follow the directions outlined in the “Directions For Use”section of this label for specific resistance management strategies foreach crop. Consult with your Federal or State Cooperative ExtensionService representatives for guidance on the proper use of ISOFETAMID400SC in programs that seek to minimize the occurrence of diseaseresistance. ISOFETAMID 400SC is not cross-resistant with otherclasses of fungicides that have different modes of action.APPLICATION AND CALIBRATION TECHNIQUES FORSPRINKLER IRRIGATIONApply this product only through center pivot, motorized lateral move,traveling gun, solid set or portable (wheel move, side roll, end tow, orhand move) irrigation system(s). DO NOT apply this product through anyother type of irrigation system.Crop injury, lack of effectiveness, or illegal pesticide residues in the cropcan result from non-uniform distribution of treated water.If you have questions about calibration, you should contact StateExtension Service specialists, equipment manufacturers or other experts.DO NOT apply ISOFETAMID 400SC through irrigation systemsconnected to a public water system. “Public water system” means asystem for the provision to the public of piped water for humanconsumption if such system has at least 15 service connections orregularly serves an average of at least 25 individuals daily at least 60 daysper year.Controls for both irrigation water and pesticide injection systems must befunctionally interlocked, so as to automatically terminate pesticideinjection when the irrigation water pump motor stops. A personknowledgeable of the irrigation system and responsible for its operationshall be present so as to discontinue pesticide injection and makenecessary adjustments, should the need arise.Page 5The irrigation water pipeline must be fitted with a functional, automatic,quick-closing check valve to prevent the flow of treated irrigation waterback toward the water source. The pipeline must also be fitted with avacuum relief valve and low-pressure drain, located between the irrigationwater pump and the check valve, to prevent back-siphoning of treatedirrigation water into the water source.Always inject ISOFETAMID 400SC into irrigation water after itdischarges from the irrigation pump and after it passes throughthecheck valve. Never inject pesticides into the intake line on thesuction side of the pump.Pesticide injection equipment must be fitted with a functional, normallyclosed, solenoid-operated valve located on the intake side of the injectionpump. Interlock this valve to the power system, so as to prevent fluidfrom being withdrawn from the chemical supply tank when the irrigationsystem is either automatically or manually turned off.The pesticide injection pipeline must contain a functional, automatic,quick-closing check valve to prevent the flow of fluid back toward theinjection pump. The irrigation line or water pump must include afunctional pressure switch that will stop the water pump motor when thewater pressure decreases to the point where pesticide distribution isadversely affected.Spray mixture in the chemical supply tank must be agitated at all times,otherwise settling and uneven application may occur. DO NOT applywhen wind speed favors drift beyond the area intended for treatment.ISOFETAMID 400SC may be used through two basic types of sprinklerirrigation systems as outlined in Sections A and B below. Determinewhich type of system is in place, then refer to the appropriate directionsprovided for each type.A. Center Pivot, Motorized Lateral Move and Traveling GunIrrigation EquipmentFor injection of pesticides, these continuously moving systems must use apositive displacement injection pump of either diaphragm or piston type,constructed of materials that are compatible with pesticides and capableof being fitted with a system interlock and capable of injection atpressures approximately 2-3 times those encountered within the irrigationwater line. Venturi applicator units cannot be used on these systems.Thoroughly mix labeled amount of this product for acreage to be coveredinto the same amount of water used during calibration and inject intosystem continuously for one revolution or run. Mixture in the chemicalsupply tank must be continuously agitated during the injection run. Shutoff injection equipment after one revolution or run, but continue tooperate irrigation system until this product has been cleared from the lastsprinkler head.B. Solid Set and Portable (Wheel Move, Side Roll, End Tow, orHand Move) Irrigation EquipmentWith stationary systems, an effectively designed in-line venturi applicatorunit is preferred which is constructed of materials that are compatible withpesticides; however, a positive-displacement pump can also be used.Determine acreage covered by sprinkler. Fill tank of injection equipmentwith water and adjust flow to use contents over a 30 to 45 minute period.Mix desired amount of ISOFETAMID 400SC for acreage to be coveredwith water so that the total mixture of this product plus water in theinjection tank is equal to the quantity of water used during calibration.Agitation is recommended. ISOFETAMID 400SC can be injected at thebeginning or end of the irrigation cycle or as a separate application. Stopinjection equipment after treatment is completed and continue to operateirrigation system until this product has been cleared from last sprinklerhead.Page 6DIRECTIONS FOR USECrop DiseasesUse RateFl. Oz. ProductPer AcreInstructionsAlmondBrown rot blossomblight (Moniliniaspp.)Anthracnose(Colletotrichum sp.)Gray mold (Botrytiscinerea)Shot hole(Wilsonomycescarpophilus)13.5 to17 fl oz(0.351 to 0.442lb. a.i. /A)Application Instructions:Initiate applications for brown rot blossom blight when conditions are favorable for disease developmentand continue on a 7-14 day interval. Typically applications are started preventatively at pink bud andcontinued through petal fall.Initiate application for control of anthracnose, gray mold, and shot hole preventatively and continue asneeded on a 7-14 day interval. If disease pressure is severe use the higher rate and shortest interval.Apply ISOFETAMID 400SC in sufficient water to obtain adequate coverage of the foliage. Sprayvolume will usually be 50 to 100 gallons per acre for dilute sprays and 5 to 10 gallons per acre for aerialsprays. For aerial applications, apply ISOFETAMID 400SC in a minimum of 5 gallons of water peracre. For dilute sprays, if higher spray volumes are desired for improved coverage, do not exceed themaximum rate of 17 fl oz of product per acre.Resistance Management:Do not make more than 2 sequential applications of ISOFETAMID 400SCor otherGroup 7containingfungicide before rotating to a fungicide with a different mode of action. Do not apply a third applicationof ISOFETAMID 400SC within 14 days of the second application.Restrictions:Do Not apply more than 68 fl oz/A/year (1.77 lb. a.i./A/year)Do Not apply after first cover.LettuceHead and LeafSclerotinia drop(Sclerotinia minor,Sclerotiniasclerotiorum)12.3 fl oz(0.320 lb a.i. /A)Application Instructions:On direct seeded lettuce make the first application after emergence, thinning or prior to onset of diseasedevelopmentOn transplanted lettuce make the first application immediately after transplanting or prior to the onset ofdisease development.Make a second application if conditions continue to favor disease development 14 days later.Apply ISOFETAMID 400SC in sufficient water to obtain adequate coverage of the foliage. Sprayvolume will usually be 50 gallons per acre for dilute sprays and 5 to 10 gallons per acre foraerial sprays.For aerial applications, apply ISOFETAMID 400SC in a minimum of 5 gallons of water per acre.Resistance Management:Do not make more than 2 sequential applications of ISOFETAMID 400SCor other Group 7 containingfungicides before rotating to a fungicide with a different mode of action.Restrictions:Do Not apply more than 24.6fl oz/A/year (0.64 lb. a.i./A/year)The Pre-Harvest Interval (PHI) for this crop is 14 days.Page 7Crop DiseasesUse RateFl. Oz. ProductPer AcreInstructionsGrapes,Crop Subgroup13-07FBotrytis bunch rot(Botrytis cinerea)Powdery mildew(Erysiphe necator)Anthracnose(Colletotrichum sp.)20 to 22 fl oz(0.520 to 0.572lb. a.i. /A)Application Instructions:For use on all types of grapes (wine, table, raisin, and juice).For bunch rot make applications at critical timings for Botrytis control. Applications are typically madeat early bloom, bunch closure, veraison and pre-harvest (at least 14 days apart). Apply with sufficientwater to allow for penetration into the foliage to obtain complete coverage using 50 to 100 gallons ofspray volume per acre.For powdery mildew and anthracnose begin fungicide applications preventatively and continue as neededon a 7 to 14-day interval. When disease pressure is severe use the higher rate and shorter interval.Resistance Management:Do not make more than 2 sequential applications of ISOFETAMID 400SCor otherGroup 7containingfungicides before rotating to a fungicide with a different mode of action. Do not apply a third applicationof ISOFETAMID 400SC within 28 days of the second application.Restrictions:Do Not apply more than 66 fl oz/A/year (1.72 lb. a.i./A/year)The Pre-Harvest Interval (PHI) for this crop is 14 days.Includes all members of the Fruit, Small Vine Climbing Crop Subgroup 13-07F, except fuzzykiwifruit: Amur river grape; gooseberry;grape; kiwifruit,hardy; maypop; schisandra berry; and cultivars, varieties, and/or hybrids of these.Low GrowingBerry, CropSubgroup 13-07GGray mold (Botrytiscinerea)Powdery mildew(Podosphaera aphanis)Anthracnose(Colletotrichumfragariae)13.5 to 15.5 floz(0.351 to 0.40lb. a.i. /A)Application Instructions:Initiate applications prior to disease development and continue on a 14-day interval. When diseasepressure is high use the high rate.Apply ISOFETAMID 400SC in sufficient water to obtain adequate coverage of the foliage. Sprayvolume will usually be 50 to 100 gallons per acre for dilute sprays and 5 to 10 gallons per acre for aerialsprays. For aerial applications, apply ISOFETAMID 400SC in a minimum of 5 gallons of water peracre.Resistance Management:Do not make more than 2 sequential applicationsof ISOFETAMID 400SCor other Group 7 containingfungicides before rotating to a fungicide with a different mode of action. Do not apply a third applicationof ISOFETAMID 400SC within 28 days of the second application.Restrictions:Do Not apply more than 54 fl oz/A/year (1.40 lb. a.i./A/year)The Pre-Harvest Interval (PHI) for this crop is 0 days.Includes all members of the Low Growing Berry Crop Subgroup 13-07G: Bearberry; bilberry; blueberry, lowbush; cloudberry; cranberry; lingonberry;muntries; partridgeberry; strawberry; and cultivars, varieties, and/or hybrids of these.Page 8Crop DiseasesUse RateFl. Oz. ProductPer AcreInstructionsRapeseed,(Canola) CropSubgroup 20ASclerotinia stem rot(Sclerotiniasclerotiorum)10.25 to 12 fl oz(0.267 to 0.312lb. a.i. /A)Application Instructions:Initiate applications at 20 to 40% flowering (BBCH 62-64) or prior to disease development. Use thehigher rates for extended disease control. A second application may be made if conditions continue to befavorable for disease development near the end of flowering (BBCH 67-69), at least 14 days later.Apply ISOFETAMID 400SC in sufficient water to obtain adequate coverage of the foliage. Spray volumewill usually be 50 to 100 gallons per acre for dilute sprays and 5 to 10 gallons per acre for aerial sprays.For aerial applications, apply ISOFETAMID 400SC in a minimum of 5 gallons of water per acre.Resistance Management:Do not make more than 2 sequential applications of ISOFETAMID 400SCor otherGroup 7containingfungicides before rotating to a fungicide with a different mode of action.Restrictions:Do Not apply more than 24 fl oz/A/year (0.63 lb. a.i./A/year)Includes all members of the Oilseed Crop Subgroup 20A: Borage; crambe; cuphea; echium; flax seed; gold of pleasure; hare’s earmustard; lesquerella;lunaria; meadowfoam; milkweed; mustard seed; oil radish; poppy seed; rapeseed (Brassica napus, B. campestris, and Crambe abyssinica(oilseed-producingvarieties only which include canola and crambe)); sesame; sweet rocket; and cultivars, varieties, and/or hybrids of these.WARRANTY AND LIMITATION OF DAMAGESSeller warrants to those persons lawfully acquiring title to this productthat at the time of first sale of this product by Seller that this productconformed to its chemical description and was reasonably fit for thepurposes stated on the label when used in accordance with Seller’sdirections under normal conditions of use. To the extent consistent withapplicable law, Buyers and users of this product assume the risk of anyuse contrary to such directions.EXCEPT AS PROVIDEDELSEWHERE IN WRITING CONTAINING AN EXPRESSREFERENCE TO THIS WARRANTY AND LIMITATION OFDAMAGES, SELLER MAKES NO OTHER EXPRESS ORIMPLIED WARRANTY OR GUARANTY, INCLUDING ANYISK Biosciences Corporation7470 Auburn Road, Suite AConcord, Ohio 44077 U.S.A.OTHER EXPRESS OR IMPLIED WARRANTY OF FITNESS OROF MERCHANTABILITY, AND NO AGENT OF SELLER ISAUTHORIZED TO DO SO.In no event shall Seller’s liability for anybreach of warranty or guaranty exceed the purchase price of the productas to which a claim is made. To the extent consistent with applicable law,Buyers and users of this product are responsible for all loss or damagefrom use or handling of this product which results from conditions beyondthe control of Seller, including, but not limited to, incompatibility withother products unless otherwise expressly provided in Directions for Useof this product, weather conditions, cultural practices, moisture conditionsor other environmental conditions outside of the ranges that are generallyrecognized as being conducive to good agricultural and/or horticulturalpractices.ISOFETAMID - 03162015