Exhibit
      4.11

    


    

    


    Collexis
      Holdings, Inc.

    1201
      Main
      Street

    Suite
      980

    Columbia,
      SC 29201

    United
      States Of America

    


    T
      (803)
      727-1113

    F
      (803)
      727-1118

    www.collexis.com

     

    Attn.
      ________________

    [ADDRESS]

     

    Reference:
      Supplement
      Agreement / Collexis Option Agreement 

     

    DATE:
      _____________

     

     

    Dear
      _________________,

     

    As
      per
      our recent discussions I herewith on behalf of Collexis Holdings,
      Inc.
      confirm
      to you as follows.

     

    The
      Collexis Option Agreement of ____________ (‘Agreement’)
      between you and Collexis B.V. (collectively: ‘Parties’)
      is incorporated herein by reference and is fully applicable to this letter
      agreement (‘Supplement
      Agreement’).

     

    On
      14
      February 2007 (‘Effective
      Date’),
      almost all shares in the share capital of Collexis B.V. were sold and
      transferred via merger to Collexis Holdings, Inc. (‘Parent’),
      which
      has triggered Section 7 (Conversion) of the Agreement as this sale, transfer
      and
      merger is a ‘Reorganization’ as defined in that Section 7.

     

    At
      the Effective Date, the right to acquire a share in
      the
      share capital of Collexis B.V., with
      a
      nominal value on Grant Date of EUR 0,05 (‘Collexis
      B.V. Share’)
      was converted into the right to acquire 10 shares of Parent Common Stock at
      an
      exercise price equal to the exercise price stated in the Agreement adjusted
      pursuant to the terms of the Agreement. reciprocally (i.e., such that the
      aggregate exercise price for all shares subject to Agreement remains
      the same after the Effective Time as before), subject in all respects to all
      other terms and conditions of the Agreement. In
      the
      case of your Agreement and Option grant(s), the related conversion results
      in
      the following numbers: 

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

    

      
        	 	
                [DATE]

              	
                ___________
                  shares

              	
                $_______

              


      

    

     

    Could
      you please confirm acceptance hereof by co-signing this letter - which I have
      sent you in duplicate - and return one copy to me on or before
      _______________.

     

    Thank
      you. Please contact me as soon as convenient if you have any queries concerning
      the content of this letter. 

     

    
      	Best
              regards,	 	 	Read
&
              consented,
	 	 	 	 
	_________________________________________________ 	 	 	_________________________________________________ 
	William
              D.
              Kirkland, CEO*** 	 	 	[NAME
              OF
              OPTIONEE]


    

     

    ***[For
      the Supplement Agreement pertaining to Mr. Kirkland’s option, the Supplement
      Agreement was signed by Mark Germain, Chairman of the Board of
      Directors.]