| x | ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
|---|------------------------------------------------------------------------------------------------|

|  ̈ | TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
|--------|----------------------------------------------------------------------------------------------------|

|                                                                     |                                |
|--------------------------------------------------------------------------|-------------------------------------|
| Delaware                                                                 | 26-3996918                          |
| (State or other jurisdiction ofincorporation or organization)            | (I.R.S. EmployerIdentification No.) |
|                                                                     |                                |
| c/o Xstelos Holdings, Inc.630 Fifth Avenue, Suite 2260New York, New York | 10020                               |
| (Address of principal executive offices)                                 | (Zip Code)                          |

|                |                                      |
|---------------------|-------------------------------------------|
| Title of each class | Name of each exchange on which registered |
| None.               | None.                                     |

| Common Stock, $0.01 Par Value Per SharePreferred Share Purchase Rights(Title of class)__________________________ |
|------------------------------------------------------------------------------------------------------------------|

|                              |                                                            |                                |   |
|-----------------------------------|-----------------------------------------------------------------|-------------------------------------|--------|
| Large accelerated filer |  ̈                                                          | Accelerated filer              | x      |
|                              |                                                            |                                |   |
| Non-accelerated filer             |  ̈  (Do not check if a smaller reporting company) | Smaller reporting company |  ̈ |

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TABLE 

|                  |                                                                                           | Page   |
|-----------------------|------------------------------------------------------------------------------------------------|--------|
| Explanatory Note |                                                                                           |
|                  | PART III                                                                                       |   |
| Item 10.         | DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE                                         |   |
| Item 11.              | EXECUTIVE COMPENSATION                                                                         |   |
| Item 12.              | SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS |   |
| Item 13.              | CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR INDEPENDENCE                      |   |
| Item 14.              | PRINCIPAL ACCOUNTANT FEES AND SERVICES                                                         |   |
|                  |                                                                                           |   |
|                  | PART IV                                                                                        |   |
| Item 15.              | EXHIBITS AND FINANCIAL STATEMENT SCHEDULES                                                     |   |
|                  |                                                                                           |   |
| Signatures            |                                                                                           |   |

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PART 

| Item  10. | DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE |
|----------------|--------------------------------------------------------|

| Name                 |   | Age |   | Position with the Company                                                             |
|----------------------|--------|-----|--------|---------------------------------------------------------------------------------------|
| Jonathan M. Couchman |   | 44  |   | Chairman of the Board, President, Chief Executive Officer and Chief Financial Officer |
| Michael C. Pearce    |   | 51  |   | Director                                                                              |
| Steven D. Scheiwe    |   | 52  |   | Director                                                                              |

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| Audit Committee:                               | Michael C. Pearce and Steven D. Scheiwe (Chair) |
|------------------------------------------------|-------------------------------------------------|
|                                           |                                            |
| Compensation Committee:                        | Michael C. Pearce (Chair) and Steven D. Scheiwe |
|                                           |                                            |
| Nominating and Corporate Governance Committee: | Michael C. Pearce (Chair) and Steven D. Scheiwe |

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| Name                 |   | Age |   | Position                                                                              |
|----------------------|--------|-----|--------|---------------------------------------------------------------------------------------|
| Jonathan M. Couchman |   | 44  |   | Chairman of the Board, President, Chief Executive Officer and Chief Financial Officer |

| Item 11. | EXECUTIVE COMPENSATION |
|---------------|------------------------|

|   | • | Jonathan M. Couchman, our President, Chief Executive Officer (January 22, 2013 – present) and Chief Financial Officer (March 1, 2013 – present). |
|--------|---------|--------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | • | David W. Gryska, our former Acting President and Chief Executive Officer (August 15, 2012 – December 24, 2012) and Chief Operating Officer (May 11, 2012 – August 15, 2012). |
|--------|---------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | • | Richard B. Brewer, our former President and Chief Executive Officer (May 11, 2012 – August 15, 2012). |
|--------|---------|------------------------------------------------------------------------------------------------------------------|

|   | • | Andrea Kendell, our former Chief Financial Officer (September 6, 2011 – February 28, 2013). |
|--------|---------|---------------------------------------------------------------------------------------------------|

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|   | • | attract and retain the best possible executive talent, |
|--------|---------|--------------------------------------------------------|

|   | • | motivate our executive officers, |
|--------|---------|----------------------------------|

|   | • | reward executive officers for their contribution to achieving our objectives through the recognition of individual leadership, initiatives, achievements and other contributions, and |
|--------|---------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | • | increase long-term shareholder value. |
|--------|---------|---------------------------------------|

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|   | • | Base Salary: Effective July 2, 2012, Ms. Kendell’s annual base salary was increased from $255,000 to $280,000. |
|--------|---------|--------------------------------------------------------------------------------------------------------------------------------|

|   | • | Annual Target Bonus: For fiscal year 2013 performance, Ms. Kendell’s annual target bonus percentage was increased from 35% to 40% of her base salary. |
|--------|---------|------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | • | Equity Grants: On July 2, 2012, Ms. Kendell was granted (i) a stock option to purchase up to 60,000 shares of common stock under our Equity Incentive Plan at an exercise price of $2.65 per share, which was equal to the closing price of the common stock on the date of grant, which vests with respect to 10,000 of the shares on the last day of each calendar quarter beginning on September 30, 2012 through November 1, 2013, and with respect to the final 10,000 shares on November 1, 2013, and (ii) 20,000 restricted stock units representing contingent rights to receive shares of our common stock, which vests in full on November 1, 2013, provided Ms. Kendell is employed by the Company on such date. |
|--------|---------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | • | Retention Bonus: A $100,000 retention bonus payable in a lump sum on the earlier of (i) November 10, 2013, provided Ms. Kendell is employed by the Company on such date, and (ii) the date Ms. Kendell’s employment is terminated by the Company without Cause or Ms. Kendell resigns for Good Reason (as such capitalized terms are defined in Ms. Kendell’s Executive Severance and Change in Control Agreement). |
|--------|---------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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|   | · | 20,000 RSUs granted on July 2, 2012 scheduled to vest on November 1, 2013; and |
|--------|--------|--------------------------------------------------------------------------------|

|   | · | 4,310 RSUs granted on September 24, 2010 scheduled to vest as to 2,155 shares on each of September 25, 2013 and September 25, 2014. |
|--------|--------|-------------------------------------------------------------------------------------------------------------------------------------|

|   | · | 60,000 options with an exercise price of $2.65 per share granted on July 2, 2012 which vest quarterly as to 10,000 shares through November 1, 2013; and |
|--------|--------|---------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | · | 80,000 of the 160,000 options granted on September 22, 2011 with an exercise price of $2.75 per share, 40,000 of which are vested and 40,000 of which vest on September 22, 2013. |
|--------|--------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | · | Ms. Kendell contined as the Company’s Chief Financial Officer on a full time basis compensated at an annual base salary of $280,000 through February 28, 2013 (the “Employment Term”). |
|--------|--------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | · | Ms. Kendell’s employment with the Company terminated as of the end of the Employment Term and she received the following, conditioned upon her execution of a release of claims: |
|--------|--------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | o | The payments and benefits currently due to her under her Executive Severance and Change in Control Agreement, dated September 22, 2011, in connection with a termination without “Cause” (as defined therein); and |
|--------|---|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | o | The retention bonus payable to her under her Retention Bonus Agreement, entered into effective July 2, 2012. |
|--------|---|--------------------------------------------------------------------------------------------------------------|

|   | · | From March 1, 2013 through June 30, 2013, Ms. Kendell was engaged as a consultant to the Company on a regular basis at a rate of $14,000 per month. |
|--------|--------|-----------------------------------------------------------------------------------------------------------------------------------------------------|

|   | · | Beginning July 1, 2013, Ms. Kendell may be engaged as a consultant to the Company on an as-needed hourly basis at a rate of $175 per hour. |
|--------|--------|--------------------------------------------------------------------------------------------------------------------------------------------|

|   |                                             |
|--------|--------------------------------------------------|
|   | MEMBERS OF THE MYREXIS, INC. BOARD OF DIRECTORS: |
|   |                                             |
|   | Michael C. Pearce (Chair)                        |
|   | Steven D. Scheiwe                                |

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| Name and Principal Position                                                                               | FiscalYear |   | Salary($) |    | Bonus($) |   | StockAwards($)(2) |    | OptionAwards($)(2) |   | AllOtherCompensation($) |   | Total($) |
|-----------------------------------------------------------------------------------------------------------|------------|--------|-----------|---------|----------|--------|-------------------|---------|--------------------|--------|-------------------------|--------|----------|
| Jonathan M. Couchman(1)                                                                                   |       |   |      |    |     |   |              |    |               |   |                    |   |     |   |   |   |   |   |   |
| President, Chief Executive Officer     and Chief Financial Officer                         | 2013       |   |      | 1       |     |   |              | 0       |               |   |                    | 0      |     |   |   | 0 |   |   |   | 0 |   |   |   | 1 |   |
| David W. Gryska(3)                                                                                        |       |   |      |    |     |   |              |    |               |   |                    |   |     |   |   |   |   |   |   |   |   |   |   |   |   |
| Former Acting President and Chief Executive     Officer and former Chief Operating Officer | 2013       |   |      | 209,230 | (4)      |   |              | 0       |               |   |                    | 0      |     |   |   | 0 |   |   |   | 16,899 | (5) |   |   | 226,129 |   |
| Richard B. Brewer(6)                                                                                      |       |   |      |    |     |   |              |    |               |   |                    |   |     |   |   |   |   |   |   |   |   |   |   |   |   |
| Former President and Chief Executive                                                                      | 2013       |   |      | 95,833  | (7)      |   |              | 0       |               |   |                    | 0      |     |   |   | 0 |   |   |   | 92 | (9) |   |   | 95,925 |   |
|         Officer                                                        | 2012       |   |      | 54,597  |     |   |              | 0       |               |   |                    | (8     | )        |   |   | 0 |   |   |   | 0 |   |   |   | 54,597 |   |
| Andrea Kendell(10)                                                                                        |       |   |      |    |     |   |              |    |               |   |                    |   |     |   |   |   |   |   |   |   |   |   |   |   |   |
| Former Chief Financial                                                                                    | 2013       |   |      | 197,292 | (11)     |   |              | 212,000 | (12)               |   |                    | 94,132 | (13)     |   |   | 0 |   |   |   | 390,697 | (14) |   |   | 894,121 |   |
|        Officer                                                              | 2012       |   |      | 244,999 | (15)     |   |              | 75,540  | (16)               |   |                    | 0      |     |   |   | 293,680 |   |   |   | 9,623 | (17) |   |   | 623,842 |   |

| (1) | Mr. Couchman was appointed to the Board and as its Chairman and as President and Chief Executive Officer of the Company on January 22, 2013 and as Chief Financial Officer of the Company on March 1, 2013. |
|-----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (2) | Represents the aggregate grant date fair value of stock awards and option awards, respectively, granted in each year presented calculated in accordance with FASB ASC Topic 718. Information regarding the assumptions used in the valuation of these awards can be found in the footnote to our financial statements entitled “Share-Based Compensation” in this Form 10-K. See also our discussion of stock-based compensation under “Management’s Discussion and Analysis of Financial Condition and Results of Operations—Critical Accounting Policies and Use of Estimates” in this Form 10-K. |
|-----|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (3) | Mr. Gryska was appointed Chief Operating Officer, effective May 11, 2012, and Acting President and Chief Executive Officer, effective August 15, 2012, and he resigned from the Company, effective December 24, 2012.  Compensation data is disclosed for Mr. Gryska only for those years for which he was a named executive officer. |
|-----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (4) | Represents salary earned at an annual base rate of $400,000 from July 1, 2012 – December 24, 2012. |
|-----|----------------------------------------------------------------------------------------------------------|

| (5) | Represents (i) a PTO payout of $8,847, (ii) $ 7,776 for matching contributions made under the Company’s 401(k) plan on behalf of Mr. Gryska and (iii) an aggregate of $276 for premiums paid by the Company with respect to term life insurance for the benefit of the executive officer. |
|-----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (6) | Mr. Brewer served as our President and Chief Executive Officer from May 11, 2012 to August 15, 2012.  Compensation data is disclosed for Mr. Brewer only for those years for which he was a named executive officer. |
|-----|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (7) | Represents salary earned at an annual base rate of $575,000 from July 1, 2012 – August 15, 2012. |
|-----|--------------------------------------------------------------------------------------------------------|

| (8) | As discussed in the Compensation Discussion and Analysis, Mr. Brewer was awarded a grant of restricted stock units on May 11, 2012 that would vest only upon the achievement of certain performance criteria, as described in the Compensation Discussion and Analysis. On the date of grant, the performance criteria were not probable of being achieved; therefore, no stock-based compensation expense has been recorded for this grant. Assuming achievement of all of the performance criteria, the grant date fair value of the award is $2,941,441. Upon Mr. Brewer’s death on August 15, 2012, the restricted stock units were terminated and no shares were issued. |
|-----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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| (9) | Represent premiums paid by the Company with respect to term life insurance for the benefit of the executive officer. |
|-----|----------------------------------------------------------------------------------------------------------------------|

| (10) | Ms. Kendell was appointed Chief Financial Officer on September 6, 2011 and resigned as Chief Financial Officer effective February 28, 2013. Compensation data is disclosed for Ms. Kendell only for those years for which she was a named executive officer. |
|------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (11) | Represents salary earned at an annual base rate of $280,000 from July 15, 2012 – February 28, 2013, and at an annual base rate of $255,000 from July 1, 2012 – July 14, 2012. |
|------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (12) | Represents a $112,000 bonus equal to 100% of her target bonus based on the payments and benefits due to her under her Executive Severance and Change in Control Agreement, dated September 22, 2011.  Additionally, Ms. Kendell received a retention bonus of $100,000 in connection with the termination of her employment with the Company at the end of the Employment Term as described in the Compensation Discussion and Analysis. |
|------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (13) | Includes 60,000 options with an exercise price of $2.65 per share granted to Ms. Kendell on July 2, 2012 that were to vest quarterly as to 10,000 shares through November 1, 2013, and 80,000 of the 160,000 options granted on September 22, 2011 with an exercise price of $2.75 per share, 40,000 of which are vested and 40,000 of which were to vest on September 22, 2013, that were converted into RSUs on February 1, 2013, into such number of RSUs that equaled the quotient of (A) the aggregate intrinsic value of such options divided by (B) the Fair Market Value (as defined in the 2009 Employee, Director and Consultant Stock Plan, as amended) of the common stock on the date of issuance of the RSUs.  For each option the intrinsic value per share was calculated by subtracting the exercise price of such option from the estimated special cash dividend per share (provided that if the exercise price of such option was greater than such amount, then the intrinsic value of such option was $0). |
|------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (14) | Represents (i) a severance payment of $280,000, (ii) PTO payout of $50,264, (iii) $3,389 for matching contributions made under the Company’s 401(k) plan on behalf of Ms. Kendell, (iv) $676 for the 2009 Employee Stock Purchase Plan and (v) an aggregate of $368 for premiums paid by the Company with respect to term life insurance for the benefit of the executive officer. |
|------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (15) | Represents salary earned at an annual base rate of $220,000 from July 1, 2011 – September 21, 2011, and at an annual base rate of $255,000 from September 22, 2011 – June 30, 2012. |
|------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (16) | Represents a $75,000 cash bonus for performance in fiscal year 2012, which was paid in the following fiscal year, as well as a holiday cash bonus of $540. |
|------|------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (17) | Represents (i) $6.28 per month for July 2011 through December 2011 and $5.53 per month for January 2012 through June 2012 of premiums paid by the Company with respect to term life insurance for the benefit of Ms. Kendell and (ii) $9,552 for matching contributions made under the Company’s 401(k) plan on behalf of Ms. Kendell. |
|------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| Name                                                                                                  | GrantDate | ApprovalDate | Estimated Future Payouts UnderEquity Incentive Plan Awards | All Other StockAwards:  Numberof Shares of Stock or Units (#) | All Other OptionAwards:  Numberof SecuritiesUnderlyingOptions (#) | Exercise orBase Price  ofOptionAwards($/Share) | Grant DateFair Value ofStock andOption Awards($)(1) |
|-------------------------------------------------------------------------------------------------------|-----------|--------------|------------------------------------------------------------|-------------------------------------------------------------------------|-----------------------------------------------------------------------------|----------------------------------------------------------|-----------------------------------------------------|
|                                                                                                  |      |         | Threshold(#)                                               | Target(#)                                                               | Maximum(#)                                                                  |                                                     |                                                |   |   |
| Jonathan M. CouchmanPresident, Chief Executive Officer and Chief Financial Officer                    | —   | —      | —                                                    | —                                                                 | —                                                                     | —                                                  | —                                             | — | — |
| David W. GryskaFormer Acting President and Chief Executive Officer and former Chief Operating Officer | —   | —      | —                                                    | —                                                                 | —                                                                     | —                                                  | —                                             | — | — |
| Richard B. BrewerFormer President and Chief Executive Officer                                         | —   | —      | —                                                    | —                                                                 | —                                                                     | —                                                  | —                                             | — | — |
| Andrea KendellFormer Chief                                                                            | 7/02/12   | 7/02/12      | —                                                    | —                                                                 | —                                                                     | 20,000(2)                                                | —                                             | — | 53,000 |
| Financial Officer                                                                                     | 7/02/12   | 7/02/12      | —                                                    | —                                                                 | —                                                                     |                                                     | 60,000                                              | 2.65 | 98,190 |

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|   | (1) | See our discussion in the footnote to our financial statements entitled “Share-Based Compensation” in this Form 10-K for details as to the assumptions used to determine the grant date fair values of these awards. See also our discussion of stock-based compensation under “Management’s Discussion and Analysis of Financial Condition and Results of Operations—Critical Accounting Policies and Use of Estimates” in this Form 10-K. |
|--------|-----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | (2) | Represents a restricted stock unit award. |
|--------|-----|-------------------------------------------|

|                                                                                                  |   | Option Awards                                     |    |   | Stock Awards                              |   |
|-------------------------------------------------------------------------------------------------------|--------|---------------------------------------------------|---------|--------|-------------------------------------------|--------|
| Name                                                                                                  |   | Number of SharesAcquired onExercise (#) |    |   | ValueRealized onExercise ($)(1) |   |   | Number ofSharesAcquiredon Vesting(#) |   |   | ValueRealizedonVesting($)(2) |   |
| Jonathan M. CouchmanPresident, Chief Executive Officer and Chief Financial Officer                    |   |                                              | — |   |                                      |   | — |   |   |   | — |   |   |   | — |   |
| David W. GryskaFormer Acting President and Chief Executive Officer and former Chief Operating Officer |   |                                              | — |   |                                      |   | — |   |   |   | — |   |   |   | — |   |
| Richard B. BrewerFormer President and Chief Executive Officer                                         |   |                                              | — |   |                                      |   | — |   |   |   | — |   |   |   | — |   |
| Andrea KendellChief Financial Officer                                                                 |   |                                              | — |   |                                      |   | — |   |   |   | 31,588 | (2) |   |   | 94,132 |   |

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| (1) | The value realized is calculated by multiplying the number of restricted stock units (“RSUs”) that vested by the closing price of our common stock on the date of vesting. |
|-----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (2) | As discussed in “Compensation Discussion and Analysis—Detailed Discussion and Analysis—Fiscal Year 2013 Compensation of Named Executive Officers,” pursuant to the terms of Ms. Kendell’s Executive Severance and Consulting Agreement 20,000 RSUs granted on July 2, 2012 scheduled to vest on November 1, 2013 and 4,310 RSUs granted on September 24, 2010 scheduled to vest as to 2,155 shares on each of September 25, 2013 and September 25, 2014, vested effective February 1, 2013.  Additionally, 60,000 options with an exercise price of $2.65 per share granted to Ms. Kendell on July 2, 2012 that were to vest quarterly as to 10,000 shares through November 1, 2013, and 80,000 of the 160,000 options granted on September 22, 2011 with an exercise price of $2.75 per share, 40,000 of which are vested and 40,000 of which were to vest on September 22, 2013, were converted into RSUs on February 1, 2013, into such number of RSUs that equals the quotient of (A) the aggregate intrinsic value of such options divided by (B) the Fair Market Value (as defined in the 2009 Employee, Director and Consultant Stock Plan, as amended) of the Common Stock on the date of issuance of the RSUs, which RSUs vested effective on February 1, 2013.  For each option the intrinsic value per share was calculated by subtracting the exercise price of such option from the estimated special cash dividend per share (provided that if the exercise price of such option was greater than such amount, then the intrinsic value of such option was $0). |
|-----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| Name                             |   | Fees Earned orPaid in Cash ($) |   |   | OptionAwards($) |   |   | Total ($) |   |
|----------------------------------|--------|---------------------------------------------------------|--------|--------|-----------------|--------|--------|-----------|--------|
| Gerald P. Belle (1)              |   |                                                    | 53,000 |   |            |   | --     |      |   |   | 53,000 |   |
| Jason M. Aryeh (1)               |   |                                                    | 24,500 |   |            |   | --     |      |   |   | 24,500 |   |
| Robert Forrester (1)             |   |                                                    | 37,000 |   |            |   | --     |      |   |   | 37,000 |   |
| John T. Henderson, M.D. (1)      |   |                                                    | 32,000 |   |            |   | --     |      |   |   | 32,000 |   |
| Dennis H. Langer, M.D., J.D. (1) |   |                                                    | 37,500 |   |            |   | --     |      |   |   | 37,500 |   |
| Timothy R. Franson, M.D. (1)     |   |                                                    | 27,000 |   |            |   | --     |      |   |   | 27,000 |   |
| Steven Scheiwe (2)               |   |                                                    | 3,806  |   |            |   | --     |      |   |   | 3,806 |   |
| Michael Pearce (2)               |   |                                                    | 3,806  |   |            |   | --     |      |   |   | 3,806 |   |

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| Item  12. | SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS |
|----------------|------------------------------------------------------------------------------------------------|

|                                                        |   | Shares of Common Stock Beneficially Owned |      |
|-------------------------------------------------------------|--------|-------------------------------------------|-----------|
| Beneficial Owner                                            |   | Number                                    |      |   | Percentage |   |
| Principal Stockholders:                                     |   |                                      |      |   |   |   |
|                                                        |   |                                      |      |   |   |   |
| Xstelos Holdings, Inc. (1)                                  |   |                                      |      |   |   |   |
| 630 Fifth Avenue, Suite 2260                                |   |                                      |      |   |   |   |
| New York, NY 10020                                          |   |                                      | 7,000,000 |   |   |   | 20.3 | % |
|                                                        |   |                                      |      |   |   |   |   |   |
| Bulldog Investors (2)                                       |   |                                      |      |   |   |   |   |   |
| Park 80 West, 250 Pehle Avenue, Suite 708                   |   |                                      |      |   |   |   |   |   |
| Saddle Brook, NJ 07663                                      |   |                                      | 2,634,889 |   |   |   | 7.6 | % |
|                                                        |   |                                      |      |   |   |   |   |   |
| Executive Officers and Directors:                           |   |                                      |      |   |   |   |   |   |
| Jonathan M. Couchman                                        |   |                                      | 0         |   |   |   | -- |   |
| Michael C. Pearce                                           |   |                                      | 0         |   |   |   | -- |   |
| Steven D. Scheiwe                                           |   |                                      | 0         |   |   |   | -- |   |
| Andrea Kendell                                              |   |                                      | 29,628    |   |   |   | * |   |
| David W. Gryska                                             |   |                                      | 0         |   |   |   | -- |   |
| Richard B. Brewer                                           |   |                                      | 0         |   |   |   | -- |   |
| All executive officers and directors as a group (6 persons) |   |                                      | 29,628    |   |   |   | * |   |

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| * | Represents beneficial ownership of less than 1% of the Common Stock outstanding. |
|---|----------------------------------------------------------------------------------|

| (1) | This information is based on a Schedule 13D filed with the SEC on March 11, 2013 by Xstelos Holdings, Inc. and Xstelos Corp.  As of the close of business on March 1, 2013, Xstelos Corp. owned directly 7,000,000 shares of Common Stock.  Xstelos Corp. is a wholly owned subsidiary of Xstelos Holdings, Inc. and, as such, Xstelos Holdings, Inc. may be deemed to beneficially own the shares of Common Stock owned directly by Xstelos Corp. |
|-----|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (2) | This information is based on a Schedule 13G filed with the SEC on February 13, 2013 by Bulldog Investors, Brooklyn Capital Management, Phillip Goldstein and Andrew Dakos, reporting sole power to dispose of all 2,634,889 shares of Common Stock beneficially owned and shared power to vote certain of the shares of Common Stock beneficially owned.  Phillip Goldstein and Andrew Dakos are principals of Bulldog Investors. |
|-----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|                                                            |   | (a)                                                                                                          |    |   | (b)                                                                                      |   |    | (c)                                                                                                                                                                  |   |
|-----------------------------------------------------------------|--------|--------------------------------------------------------------------------------------------------------------|---------|--------|------------------------------------------------------------------------------------------|--------|---------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------|
| Plan category                                                   |   | Number of securities to beissued upon exercise ofoutstanding options,warrants and rights |    |   | Weighted-average exerciseprice of outstanding options,warrants and rights |   |    | Number of securitiesremaining available forfuture issuance underequity compensationplans (excluding securitiesreflected in column (a)) |   |
| Equity compensation plans approved by security holders (1) |   |                                                                                                         | 886,360 | (2)    |                                                                                     | $      | 3.73    | (3)                                                                                                                                                                  |   |   | 886,360 | (4) |
|                                                            |   |                                                                                                         |    |   |                                                                                     |   |    |                                                                                                                                                                 |   |   |   |   |
| Equity compensation plans not approved by security holders      |   |                                                                                                         | — |   |                                                                                     |   | — |                                                                                                                                                                 |   |   | — |   |
|                                                            |   |                                                                                                         |    |   |                                                                                     |   |    |                                                                                                                                                                 |   |   |   |   |
| Total                                                           |   |                                                                                                         | 886,360 | (2)    |                                                                                     | $      | 3.73    | (3)                                                                                                                                                                  |   |   | 886,360 | (4) |

| (1) | These plans consist of our 2009 Employee, Director and Consultant Equity Incentive Plan (the “2009 Equity Incentive Plan”) and our 2009 Employee Stock Purchase Plan (the “2009 ESPP”). |
|-----|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (2) | Includes 886,360 shares of common stock to be issued upon the exercise of outstanding stock options under the 2009 Equity Incentive Plan, and 0 shares of common stock to be issued upon the vesting of restricted stock units granted under the 2009 Equity Incentive Plan as of June 30, 2013. |
|-----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (3) | Weighted-average exercise price relates to outstanding stock options. Restricted stock units are deemed to have an exercise price of zero. |
|-----|--------------------------------------------------------------------------------------------------------------------------------------------|

| (4) | Represents shares of common stock available for future issuance under the 2009 Equity Incentive Plan and the 2009 ESPP as of June 30, 2013. The 2009 Equity Incentive Plan contains an “evergreen provision” which allows for an annual increase in the number of shares available for issuance under the plan on the first day of each of our fiscal years during the period beginning in fiscal year 2011 and ending on the second day of fiscal year 2019. The annual increase in the number of shares shall be equal to the lesser of (i) 2,400,000 shares; (ii) 5% of our outstanding shares on the first day of the fiscal year; and (iii) an amount determined by our Board of Directors.  The Board of Directors determined not to increase the number of shares reserved under the Equity Incentive Plan as of July 1, 2012. The 2009 ESPP also contains an evergreen provision which allows for an increase in the number of shares available for issuance under the plan on the first day of each fiscal year beginning with fiscal year 2011. The increase in the number of shares shall be equal to the lesser of (i) 500,000 shares; (ii) 2% of the shares of our common stock outstanding on the last day of the immediately preceding fiscal year; and (iii) an amount determined by our Board of Directors. The Board of Directors determined not to increase the number of shares reserved under the 2009 ESPP as of July 1, 2012. |
|-----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| Item  13. | CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR INDEPENDENCE |
|----------------|---------------------------------------------------------------------------|

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|   | • | executive officers of the Company; |
|--------|---------|------------------------------------|

|   | • | members of our Board of Directors; |
|--------|---------|------------------------------------|

|   | • | beneficial holders of more than 5% of our securities; |
|--------|---------|-------------------------------------------------------|

|   | • | immediate family members, as defined by Item 404 of Regulation S-K promulgated under the Securities Act, of any of the foregoing persons; |
|--------|---------|------------------------------------------------------------------------------------------------------------------------------------------------|

|   | • | any firm, corporation or other entity in which any of the foregoing persons is employed or is a partner or principal or in a similar position or in which such person has a 5% or greater beneficial ownership interest; and |
|--------|---------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | • | any other persons whom the Board determines may be considered to be related persons as defined by Item 404 of Regulation S-K promulgated under the Securities Act. |
|--------|---------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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| Item  14. | PRINCIPAL ACCOUNTANT FEES AND SERVICES |
|----------------|----------------------------------------|

|                    |   | 2013 ($) |   |
|-------------------------|--------|----------|--------|
| Audit fees: (1)         |   |     | 40,000 |   |
| Audit related fees: (2) |   |     | 0      |   |
| Tax fees:               |   |     | 0      |   |
| All other fees:         |   |     | 0      |   |
| Total                   |   |     | 40,000 |   |

| (1) | Audit fees consisted of audit work performed in the preparation of financial statements, as well as work generally only the independent registered public accounting firm can reasonably be expected to provide, such as statutory audits. |
|-----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (2) | We did not engage EisnerAmper to perform audit related services during fiscal year 2013. |
|-----|------------------------------------------------------------------------------------------|

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|                    |   | 2012   |    |
|-------------------------|--------|--------|---------|
| Audit fees: (1)         |   | $      | 232,096 |   |
| Audit related fees: (2) |   |   | — |   |
| Tax fees: (3)           |   |   | 22,900  |   |
| All other fees: (4)     |   |   | 1,995   |   |
| Total                   |   | $      | 256,991 |   |

| (1) | Audit fees consisted of audit work performed in the preparation of financial statements, as well as work generally only the independent registered public accounting firm can reasonably be expected to provide, such as statutory audits. |
|-----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (2) | We did not engage Ernst & Young LLP to perform audit related services during fiscal year 2012. |
|-----|---------------------------------------------------------------------------------------------------------|

| (3) | Tax fees in fiscal 2012 consisted principally of assistance with matters related to a Section 382 study. |
|-----|---------------------------------------------------------------------------------------------------------------|

| (4) | All other fees in fiscal year 2012 consisted principally of access fees to the Ernst & Young LLP on-line Global Accounting & Auditing Information Tool. |
|-----|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | 1. | Audit services include audit work performed in the preparation of financial statements, as well as work that generally only an independent registered public accounting firm can reasonably be expected to provide, including comfort letters, statutory audits, and attest services and consultation regarding financial accounting and/or reporting standards. |
|--------|----|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | 2. | Audit-Related services are for assurance and related services that are traditionally performed by an independent registered public accounting firm, including due diligence related to mergers and acquisitions, employee benefit plan audits, and special procedures required to meet certain regulatory requirements. |
|--------|----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | 3. | Tax services include all services performed by an independent registered public accounting firm’s tax personnel except those services specifically related to the audit of the financial statements, and includes fees in the areas of tax compliance, tax planning, and tax advice. |
|--------|----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | 4. | Other Fees are those associated with services not captured in the other categories. |
|--------|----|-------------------------------------------------------------------------------------|

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PART 

| Item  15. | EXHIBITS AND FINANCIAL STATEMENT SCHEDULES |
|----------------|--------------------------------------------|

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SIGNATURES

|          |                                                                               |
|---------------|------------------------------------------------------------------------------------|
| MYREXIS, INC. |
|          |                                                                               |
| By:           | /s/ Jonathan M. Couchman                                                           |
|          | Jonathan M. CouchmanPresident, Chief Executive Officer and Chief Financial Officer |

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|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
|--------------------------------------------------|--------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------|---------------------------|--------|----------------------------------------------------------------|--------|------------|--------|------------------------------|
| ExhibitNumber                                    |   | Exhibit Description                                                                                                                                                                                            |   | Filedwith thisReport |   | Incorporated byReference  hereinfrom Form orSchedule |   | FilingDate |   | SEC File /RegistrationNumber |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| 2.1                                              |   | Separation and Distribution Agreement, dated June 30, 2009, by and between the Registrant and Myriad Genetics, Inc.                                                                                       |   |                      |   | 8-K(Exhibit 2.1)                                               |   | 7/7/09     |   | 001-34275                    |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| 3.1                                              |   | Amended and Restated Certificate of Incorporation of the Registrant                                                                                                                                            |   |                      |   | 10-K(Exhibit 3.1)                                              |   | 9/13/10    |   | 001-34275                    |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| 3.1.1                                            |   | Certificate of Designation, Preferences and Rights of Series A Junior Participating Preferred Stock                                                                                                            |   |                      |   | 10-K(Exhibit 3.1.1)                                       |   | 9/13/10    |   | 001-34275                    |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| 3.1.2                                            |   | Certificate of Amendment to Restated Certificate of Incorporation of the Registrant                                                                                                                            |   |                      |   | 10-K(Exhibit 3.1.2)                                       |   | 9/13/10    |   | 001-34275                    |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| 3.1.3                                            |   | Amended Certificate of Designation, Rights and Preferences of Series A Junior Participating Preferred Stock                                                                                                    |   |                      |   | 8-K(Exhibit 3.1)                                               |   | 3/30/12    |   | 001-34275                    |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| 3.1.4                                            |   | Certificate of Amendment to Restated Certificate of Incorporation of the Registrant                                                                                                                            |   |                      |   | 8-K(Exhibit 3.1)                                          |   | 9/13/10    |   | 001-34275                    |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| 3.2                                              |   | Amended and Restated Bylaws of the Registrant                                                                                                                                                                  |   |                      |   | 10-K(Exhibit 3.2)                                              |   | 9/13/10    |   | 001-34275                    |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| 4.1                                              |   | Form of Common Stock Certificate of the Registrant                                                                                                                                                             |   |                      |   | 10-K(Exhibit 4.1)                                              |   | 9/13/12    |   | 001-34275                    |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| 4.2                                              |   | Shareholder Rights Agreement between the Registrant and American Stock Transfer & Trust Company, LLC, dated June 30, 2009, which includes as Exhibit B the form of Right Certificate                       |   |                      |   | 8-A(Exhibit 4.1)                                               |   | 6/30/09    |   | 001-34275                    |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| 4.2.1                                            |   | First Amendment, dated March 29, 2012, to Shareholder Rights Agreement by and between the Registrant and American Stock Transfer & Trust Company, LLC, dated June 30, 2009                                 |   |                      |   | 8-K(Exhibit 4.1)                                               |   | 3/30/12    |   | 001-34275                    |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| 4.3                                              |   | Tax Benefits Preservation Rights Agreement by and between the Registrant and American Stock Transfer & Trust Company, LLC, dated March 29, 2012, which includes as Exhibit B the Form of Right Certificate |   |                      |   | 8-K(Exhibit 4.2)                                               |   | 3/30/12    |   | 001-34275                    |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |
| Agreements with Executive Officers and Directors |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| *10.9                                            |   | Separation Agreement by and between the Registrant and Adrian N. Hobden, dated July 21, 2011                                                                                                              |   |                      |   | 8-K(Exhibit 10.1)                                         |   | 7/22/11    |   | 001-34275                    |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| *10.10                                           |   | Offer Letter by and between the Registrant and Robert J. Lollini, dated September 9, 2011                                                                                                                      |   |                      |   | 8-K(Exhibit 10.1)                                         |   | 9/12/11    |   | 001-34275                    |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| *10.11                                           |   | First Amendment, dated September 9, 2011, to Executive Severance and Change in Control Agreement by and between the Registrant and Robert J. Lollini, dated February 1, 2010                                   |   |                      |   | 8-K(Exhibit 10.2)                                         |   | 9/12/11    |   | 001-34275                    |
|                                             |   |                                                                                                                                                                                                           |   |                      |   |                                                           |   |       |   |                         |
| *10.12                                           |   | Offer Letter by and between the Registrant and Andrea Kendell, dated September 22, 2011                                                                                                                        |   |                      |   | 8-K/A(Exhibit 10.1)                                       |   | 9/28/11    |   | 001-34275                    |

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|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
|---------------------------|--------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------|--------|--------|--------------------------|--------|----------|--------|-----------|
| *10.13                    |   | Executive Severance and Change in Control Agreement by and between the Registrant and Andrea Kendell, dated September 22, 2011                                                                                                                                        |   |   |   | 8-K/A(Exhibit 10.2) |   | 9/28/11  |   | 001-34275 |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
|   10.14         |   | Agreement by and between the Registrant and Jason M. Aryeh, dated October 18, 2011                                                                                                                                                                                    |   |   |   | 8-K(Exhibit 10.2)   |   | 10/21/11 |   | 001-34275 |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
| *10.15                    |   | Separation Agreement by and between the Registrant and Wayne Laslie, dated December 13, 2011                                                                                                                                                                     |   |   |   | 8-K(Exhibit 10.1)   |   | 12/14/11 |   | 001-34275 |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
| *10.16                    |   | Separation and Consulting Agreement by and between the Registrant and Robert J. Lollini, dated May 11, 2012                                                                                                                                                           |   |   |   | 8-K(Exhibit 10.1)   |   | 5/11/12  |   | 001-34275 |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
| *10.17                    |   | Employment Agreement by and between the Registrant and Richard B. Brewer, dated May 9, 2012                                                                                                                                                                           |   |   |   | 8-K(Exhibit 10.2)   |   | 5/11/12  |   | 001-34275 |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
| *10.18                    |   | Employment Agreement by and between the Registrant and David W. Gryska, dated May 9, 2012                                                                                                                                                                             |   |   |   | 8-K(Exhibit 10.3)   |   | 5/11/12  |   | 001-34275 |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |
| Other Material Agreements |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
|   10.21         |   | Agreement by and among the Registrant and MSMB Healthcare LP, MSMB Healthcare Investors LLC, MSMB Healthcare Management LLC, and MSMB Capital Management LLC, dated October 18, 2011                                                                             |   |   |   | 8-K(Exhibit 10.1)   |   | 10/21/11 |   | 001-34275 |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
|   10.22         |   | Letter Agreement by and between the Registrant and Martin Shkreli, dated October 18, 2011                                                                                                                                                                             |   |   |   | 8-K(Exhibit 10.3)   |   | 10/21/11 |   | 001-34275 |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
|   10.23         |   | Letter Agreement by and among the Registrant, Bulldog Investors, and Brooklyn Capital Management LLC, dated August 6, 2012                                                                                                                                            |   |   |   | 8-K(Exhibit 10.1)   |   | 8/10/12  |   | 001-34275 |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
|   10.24         |   | Letter Agreement by and among the Registrant, MSMB Healthcare LP, MSMB Healthcare Investors LLC, MSMB Healthcare Management LLC and MSMB Capital Management LLC, dated August 8, 2012                                                                                 |   |   |   | 8-K(Exhibit 10.2)   |   | 8/10/12  |   | 001-34275 |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
|   10.25         |   | Letter Agreement by and between the Registrant and Martin Shkreli, dated August 8, 2012                                                                                                                                                                          |   |   |   | 8-K(Exhibit 10.3)   |   | 8/10/12  |   | 001-34275 |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
|   10.26         |   | Settlement Agreement, dated December 20, 2012, between and among Alzheimer’s Institute of America, Inc., and the Registrant, Myriad Genetics, Inc., Myriad Therapeutics, Inc., Mayo Clinic Jacksonville and Mayo Foundation for Medical Education and Research. |   |   |   | 10-Q(Exhibit 10.2)  |   | 2/08/13  |   | 001-34275 |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
|   10.27         |   | Stock Purchase Agreement by and between the Registrant and Xstelos Corp., dated February 27, 2013                                                                                                                                                                     |   |   |   | 10-Q(Exhibit 10.1)  |   | 5/10/13  |   | 001-34275 |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
|   31.1          |   | Certification of the Chief Executive Officer under Section 302 of the Sarbanes-Oxley Act of 2002                                                                                                                                                                 |   |   |   | 10-K(Exhibit 31.1)  |   | 7/17/13  |   | 001-34275 |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
|   31.1.1        |   | Certification of the Chief Executive Officer under Section 302 of the Sarbanes-Oxley Act of 2002                                                                                                                                                                 |   | X      |   |                     |   |     |   |      |
|                      |   |                                                                                                                                                                                                                                                                  |   |   |   |                     |   |     |   |      |
|   31.2          |   | Certification of the Chief Financial Officer under Section 302 of the Sarbanes-Oxley Act of 2002                                                                                                                                                                 |   |   |   | 10-K(Exhibit 31.2)  |   | 7/17/13  |   | 001-34275 |

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|               |   |                                                                                                                                                                                                                                                                                                                                                                                   |   |   |   |                    |   |    |   |      |
|--------------------|--------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------|--------|--------|-------------------------|--------|---------|--------|-----------|
|   31.2.1 |   | Certification of the Chief Financial Officer under Section 302 of the Sarbanes-Oxley Act of 2002                                                                                                                                                                                                                                                                                  |   | X      |   |                    |   |    |   |      |
|               |   |                                                                                                                                                                                                                                                                                                                                                                                   |   |   |   |                    |   |    |   |      |
|   32.1   |   | Certification of the Chief Executive Officer and the Chief Financial Officer under Section 906 of the Sarbanes- Oxley Act of 2002                                                                                                                                                                                                                                                 |   |   |   | 10-K(Exhibit 32.1) |   | 7/17/13 |   | 001-34275 |
|               |   |                                                                                                                                                                                                                                                                                                                                                                                   |   |   |   |                    |   |    |   |      |
|   101**  |   | The following materials from Myrexis, Inc.’s Annual Report on Form 10-K for the fiscal year ended June 30, 2013, formatted in XBRL (extensible Business Reporting Language): (i) Balance Sheets, (ii) Statements of Operations, (iii) Statements of Stockholders’ Equity and Comprehensive Loss, (iv) Statements of Cash Flows, and (v) Notes to Financial Statements |   |   |   | 10-K(Exhibit 101)  |   | 7/17/13 |   | 001-34275 |

| * | Management contract, compensatory plan or arrangement. |
|---|--------------------------------------------------------|

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