2 Huntsman Corporation on behalf of the Join t Inerts Task Force, Cluster Support Team 8 (JITF CST 8) submitted a petition (2E8087) re questing to amend two exemptions from the requirement of a tolerance for di methylaminopropylamine, isopropylamine, ethanolamine, and trietha nolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid (without limitation) and diethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid (not to exceed 7% in pesticidal formulations) under 40 CFR 180.920 and 180.930. This request is to amend the existing tolerance exemptions to include additional CAS Reg. Nos. (See Table 1 and Table 2). A Notice of Filing for this petition was published in the Federal Register on June 5, 2013 (78 FR 33785). There were no comments received in response to this notice.

The purpose of this document is to assess, as required under the Federal Food Drug and Cosmetic Act (FFDCA), the risk of the us e of the additional CAS Reg. Nos. as inert ingredients in pesticide products and is ba sed on a previous assessment for the subject chemicals along with a rationale provided by the petitioner as to why the additional CAS Reg. Nos. can be considered safe under the existing tolerance exemption descriptors for dimethylaminopropylamine, isopropylamine, etha nolamine, and triethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid and diethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid; under 40 CFR 180.920 & 180.930.

A previous assessment was completed on July 23, 2009 and a final rule establishing exemptions from the requirement of a tolerance for residues of dimethylaminopropylamine, isopropylamine, etha nolamine, and triethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid and diethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid under 40 CF R 180.920 and 180.930 was published on August 5, 2009 (74 FR 38924).

These exemptions were established based on information submitted by the JITF CST 8. Specific information on the studies received from the JITF CST 8 to support the request to establish exemptions from the requirement a tolerance and the nature of the adverse effects caused by dimethylaminopropylamin e, isopropylamine, ethanolamine, and triethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid and di ethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid as well as the no- observed-adverse-effect-level (NOAEL) and the lowest-observed-adverse-e ffect-level (LOAEL) from the toxicity studies can be found at http:// www.regulations.gov in documents “Dimethylaminopropylamine, Isopropylamine, Ethanolamine, and Triethanolamine Salts of Alkyl (C 8 -C 24 ) Benzenesulfonic acid (JITF CST 8 In ert Ingredients). Human Health Risk Assessment to Support Proposed Exemp tion from the Requirement of a Tolerance When Used as Inert Ingredient in Pesticide Formulations.” and “Die thanolamine Salts of Alkyl (C 8 -C 24 ) Benzenesulfonic Acid (DEA – JITF CST 8 Inert Ingredient). Human Health Risk Assessment to Support Proposed Exemption from the Requirement of a Tolerance When Used as Inert Ingredient in Pesticide Formulat ions.” in docket ID number EPA-HQ-OPP-2008-0889.3 The Agency has reviewed the JITF CST 8’s cl aim that the addition of the requested CAS Reg. Nos. is acceptable under the current tolerance exemption descriptors for dimethylaminopropylamine, isopropylamine, etha nolamine, and triethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid and diethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid. IIAB has confirme d that the requested CAS Reg. Nos. are appropriately added to the currently approved descriptors and that no further review is required. The requested CAS Registry Number s all describe compounds that are either dimethylaminopropylamine, isopropylamine, etha nolamine, and triethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid or diet hanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid and, as such, fall within the existing tolerance exemption descriptors in 40 CFR 180.920 and 40 CFR 180.930.

The Agency has determined that the proposed addition of the requested CAS Reg. Nos. is adequately supported by the existing data and assessment and that no additional data or review is required. Inclusi on of the additional chemicals described above in the risk assessments for the dimethylaminopropylamine, isopropylamine, ethanolamine, and triethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid and diethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid would in no way alter the prior risk assessment given the generic findings on toxicity and the worst case exposure assumptions used in the risk assessment. Accordingly, based on the findings in that earlier rule, EPA has determined that there is a reasonable certainty that no harm to a ny population subg roup, including infants and children, will result from aggr egate exposure to dimethylaminopropylamine, isopropylamine, ethanolamine, and triethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid and diet hanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid by including the additional chemicals descri bed in Tables 1 and 2, under reasonably foreseeable circumstances.

Therefore, the amendment of an exemp tion from tolerance under 40 CFR 180.920 and 180.930 for residues of dimethylaminopropylamin e, isopropylamine, ethanolamine, and triethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid and diethanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid (not to exceed 7% of pesticidal formulations) to include the requested CAS Reg. Nos. (See Ta ble 1 and Table 2) when used as inert ingredients (surfactants) in pesticide form ulations applied to growing crops and to animals can be considered safe under section 408 of the FFDCA.

Table 1. Request to Amend Dimethyl aminopropylamine, isopropylamine, ethanolamine, and triethan olamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid under 40 CFR 180.920 and 40 CFR 180.930 to incl ude the following CAS Reg. Nos.

CAS Numbers Chemical Names

12068-12-1 Benzenesulfonic acid, dod ecyl-, compd. with N,N-dimethyl-1,3- propanediamine (1:1) 121617-08-1 Benzenesulfonic acid, 4-C10- 13-sec-alkyl derivs., compds. with triethanolamine 193562-36-6 Benzenesulfonic acid, C 16-24-alkyl derivs., compds. with4 ethanolamine (1:1) (TSCA 26836-07-7 Benzenesulfonic acid, dodecyl- , compd. with 2-am inoethanol (1:1) (TSCA, DSL 3088-30-0 p-dodecylbenzenesulphoni c acid, compound with 2,2',2''- nitrilotriethanol (1:1) 58089-99-9 Benzenesulfonic acid, 4-dod ecyl-, compd. with 2-aminoethanol (1:1) (TSCA, DSL 61886-59-7 Benzenesulfonic acid, tridecyl-, compd. with 2,2',2''- nitrilotris[ethanol] (1:1) 61931-76-8 Benzenesulfonic acid, undecyl-, compd. with 2,2',2''- nitrilotris[ethanol] (1:1) 67924-05-4 Benzenesulfonic acid, 4-dodecyl-, compd. with 2,2',2''- nitrilotris[ethanol] homopolymer (TSCA, NDSL) 68110-32-7 Benzenesulfonic acid, 3-dod ecyl-, compd. with 2-aminoethanol (1:1) (TSCA, NDSL 68259-35-8 Benzenesulfonic acid, undecyl- , compd. with 2-propanamine (1:1) 68442-72-8 Benzenesulfonic acid, d odecyl-, reaction products with ethanolamine (TSCA, NDSL 68567-69-1 Benzenesulfonic acid, 4-s ec-dodecyl-, compd. with 2,2',2''- nitrilotris[ethanol] (1:1) 68815-30-5 Benzenesulfonic acid, de cyl-, branched, compds. with triethanolamine 68815-35-0 Benzenesulfonic acid, tetradecyl-, branched, compds. with triethanolamine 68953-98-0 Benzenesulfonic acid, dodecyl-, branched, compds. with ethanolamine (TSCA 70528-84-6 Benzenesulfonic acid, dodecyl-, branched, compds. with triethanolamine 72391-21-0 Benzenesulfonic acid, 4-[2,4,4-trimethyl-1-(2- methylpropyl)pentyl]-, compd. with 2-aminoethanol (1:1) (TSCA 84961-74-0 Benzenesulfonic acid, 4-C10-13- sec-alkyl derivs., compds. with 2- propanamine 85480-55-3 Benzenesulfonic acid, mono- C10-13-alkyl derivs., compds. with ethanolamine (REACH 85480-56-4 Benzenesulfonic acid, mono- C10-13-alkyl derivs., compds. with triethanolamine 85995-82-0 Benzenesulfonic acid, 4-C 10-14-alkyl derivs., compds. with ethanolamine (DSL 90194-54-0 Benzenesulfonic acid, m ono-C10-13-branched alkyl derivs., compds. with 2-propanamine 90194-55-1 Benzenesulfonic acid, m ono-C10-13-branched alkyl derivs., compds. with triethanolamine 90218-09-0 Benzenesulfonic acid, mono- C8-24-branched and linear alkyl derivs., compds. with ethanolamine (REACH 90218-11-4 Benzenesulfonic acid, mono- C16-24-branched and linear alkyl derivs., compds. with 2-propanamine5 96687-54-6 tetrapropylenebenzenesul phonic acid, compound with 2,2',2''- nitrilotriethanol (1:1) 99924-49-9 Benzenesulfonic acid, mono-C 10-14-alkyl derivs., compds. with ethanolamine (TSCA

Table 2. Request to Amend Diet hanolamine salts of alkyl (C 8 -C 24 ) benzenesulfonic acid under 40 CFR 180.920 and 40 CFR 180.930 to include the following CAS Reg.
Nos. CAS Numbers Chemical Names
67815-95-6 Benzenesulfonic aci d, 4-dodecyl-, compd. with 2,2'- iminobis[ethanol] (1:1) (TSCA, NDSL, REACH
67889-94-5 Benzenesulfonic aci d, isoundecyl-, compd. with 2,2'- iminobis[ethanol] (1:1) 67889-95-6 Benzenesulfonic acid, isodecy l-, compd. with 2,2'-iminobis[ethanol] (1:1) 68259-34-7 Benzenesulfonic acid, undecy l-, compd. with 2,2'-iminobis[ethanol] (1:1) 68478-47-7 Benzenesulfonic acid, d odecyl-, reaction products with diethanolamine (TSCA, NDSL, REACH 68567-68-0 Benzenesulfonic acid, 4-sec-dodecyl-, compd. with 2,2'- iminobis[ethanol] (1:1) (TSCA, NDSL, REACH 68815-34-9 Benzenesulfonic acid, tetradecyl-, branched, compds. with diethanolamine 68815-37-2 Benzenesulfonic acid, tridecyl-, branched, compds. with diethanolamine 68891-02-1 Benzenesulfonic acid, mono- C10-16-alkyl derivs., compds. with diethanolamine (TSCA, NDSL, REACH 84989-15-1 Benzenesulfonic acid, 4-C10- 13-sec-alkyl derivs., compds. with diethanolamine 85338-09-6 Benzenesulfonic acid, 4-C 10-14-alkyl derivs., compds. with diethanolamine 90194-39-1 Benzenesulfonic acid, mono- C10-13-alkyl derivs., compds. with diethanolamine 90194-40-4 Benzenesulfonic acid, mono- C10-14-alkyl derivs., compds. with diethanolamine 90218-08-9 Benzenesulfonic acid, mono- C8-24-branched and linear alkyl derivs., compds. with diethanolamine