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EXHIBIT 4.4




SUPPLEMENTAL INDENTURE




     FIRST SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of February 25, 2010,
among Abrazo Medical Group Urgent Care, LLC, a Delaware limited liability company (“AMC”), Central
Texas Corridor Hospital Company, LLC, a Delaware limited liability company (“CTCH”; AMC and CTCH,
collectively, referred to herein as the “New Guarantors”), each of the New Guarantors being a
subsidiary of Vanguard Health Holding Company II, LLC, a Delaware limited liability company (“VHS
Holdco II”), Vanguard Holding Company II, Inc., a Delaware corporation and a wholly owned
subsidiary of VHS Holdco II (together with VHS Holdco II, the “Issuers”), Vanguard Health Holding
Company I, LLC, Vanguard Health Systems, Inc. and U.S. Bank National Association, as trustee under
the Indenture referred to below (the “Trustee”).



WITNESSETH




     WHEREAS, the Issuers and the existing Guarantors have heretofore executed and delivered to the
Trustee an indenture (as amended, supplemented or otherwise modified, the “Indenture”), dated as of
January 29. 2010 providing for the issuance of 8% Senior Notes due 2018 (the “Notes”);



     WHEREAS, Section 4.13 of the Indenture provides that under certain circumstances the New
Guarantors shall execute and deliver to the Trustee a supplemental indenture pursuant to which the
New Guarantors shall unconditionally guarantee all of the Issuers’ Obligations under the Notes and
the Indenture on the terms and conditions set forth herein (the “Guarantee”); and



     WHEREAS, pursuant to Section 9.01 of the Indenture, the Trustee and the Issuers are authorized
to execute and deliver this Supplemental Indenture.



     NOW, THEREFORE, in consideration of the foregoing and for other good and valuable
consideration, the receipt of which is hereby acknowledged, the New Guarantors, the Issuers and the
Trustee mutually covenant and agree for the equal and ratable benefit of the Holders of the Notes
as follows:



     1. Defined Terms. Defined terms used herein without definition shall have the
meanings assigned to them in the Indenture.



     2. Agreement to Guarantee. The New Guarantors hereby agree, jointly and severally with all
existing Guarantors (if any), to provide an unconditional Guarantee on the terms and subject to the
conditions set forth in Article X of the Indenture and to be



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bound by all other applicable provisions of the Indenture and the Notes and to perform all of the
obligations and agreements of a Guarantor under the Indenture.




     3. No Recourse Against Others. No past, present or future director, manager, officer,
employee, incorporator, stockholder or member of the Issuers, any parent entity of the Issuers or
any Subsidiary, as such, shall have any liability for any obligations of the Issuers or the
Guarantors under the Notes, this Indenture, the Guarantees or for any claim based on, in respect
of, or by reason of, such obligations or their creation. Each Holder of Notes by accepting a Note
waives and releases all such liability. The waiver and release are part of the consideration for
issuance of the Notes. The waiver may not be effective to waive liabilities under the federal
securities laws.



     4. Notices. All notices or other communications to the New Guarantors shall be given
as provided in Section 12.02 of the Indenture.



     5. Ratification of Indenture; Supplemental Indentures Part of Indenture. Except as
expressly amended hereby, the Indenture is in all respects ratified and confirmed and all the
terms, conditions and provisions thereof shall remain in full force and effect. This Supplemental
Indenture shall form a part of the Indenture for all purposes, and every Holder of Notes heretofore
or hereafter authenticated and delivered shall be bound hereby.



     6. GOVERNING LAW. THIS INDENTURE, THE NOTES AND THE GUARANTEES SHALL BE GOVERNED BY,
AND CONSTRUED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW YORK.



     7. Counterparts. The parties may sign any number of copies of this Supplemental
Indenture. Each signed copy shall be an original, but all of them together represent the same
agreement.



     8. Effect of Headings. The section headings herein are for convenience only and shall
not affect the construction hereof.



     9. Trustee Makes No Representation. The Trustee makes no representation as to the
validity or sufficiency of this Supplemental Indenture.



     [The rest of this page is intentionally blank]



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     IN WITNESS WHEREOF, the parties hereto have caused this Supplemental Indenture to be duly
executed and attested, all as of the date first above written.



	 	 	 	 	 
	Dated: February 25, 2010
	 	 	 	 
	 
	 	 	 	 
	 

	 	ABRAZO MEDICAL GROUP URGENT CARE, LLC
	 
	 	 	 	 
	 

	 	By:
	 	/s/ James H. Spalding
	 

	 	 	 	 
	 

	 	 	 	Name: James H. Spalding

Title: Senior Vice President
	 
	 	 	 	 
	 

	 	CENTRAL TEXAS CORRIDOR HOSPITAL COMPANY, LLC
	 
	 	 	 	 
	 

	 	By:
	 	/s/ James H. Spalding
	 

	 	 	 	 
	 

	 	 	 	Name: James H. Spalding

Title: Senior Vice President
	 
	 	 	 	 
	 

	 	VANGUARD HEALTH HOLDING COMPANY II, LLC
	 
	 	 	 	 
	 

	 	By:
	 	/s/ James H. Spalding
	 

	 	 	 	 
	 

	 	 	 	Name: James H. Spalding

Title: Senior Vice President
	 
	 	 	 	 
	 

	 	VANGUARD HOLDING COMPANY II, INC.
	 
	 	 	 	 
	 

	 	By:
	 	/s/ James H. Spalding
	 

	 	 	 	 
	 

	 	 	 	Name: James H. Spalding

Title: Senior Vice President






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	 	VANGUARD HEALTH HOLDING COMPANY I, LLC
	 
	 	 	 	 
	 

	 	By:
	 	/s/ James H. Spalding
	 

	 	 	 	 
	 

	 	 	 	Name: James H. Spalding

Title: Senior Vice President
	 
	 	 	 	 
	 

	 	VANGUARD HEALTH SYSTEMS, INC.
	 
	 	 	 	 
	 

	 	By:
	 	/s/ James H. Spalding
	 

	 	 	 	 
	 

	 	 	 	Name: James H. Spalding

Title: Senior Vice President
	 
	 	 	 	 
	 

	 	U.S. BANK NATIONAL
ASSOCIATION,
as Trustee
	 
	 	 	 	 
	 

	 	By:
	 	/s/ Richard Prokosch
	 

	 	 	 	 
	 

	 	 	 	Authorized Signatory







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