UNITED
STATES SECURITIES AND EXCHANGE COMMISSION



Washington, D.C. 20549

Form 10-K

|S | ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIESEXCHANGE ACT OF 1934
|- | ------------------------------------------------------------------------------------



For the Fiscal year ended December 31,
2011

or



|£ | TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
|- | ----------------------------------------------------------------------------------------



For the transition period from ______ to
_________



Commission File Number 1-16695

Radient Pharmaceuticals Corporation

(Exact name of registrant as specified
in its charter)



|Delaware                                                                                                             |  | 33-0413161                                                                         
|-------------------------------------------------------------------------------------------------------------------- |  | -----------------------------------------------------------------------------------
|(State or other jurisdiction of
        incorporation or organization)                                               |  | (IRS Employer
        Identification No.)                                          
|                                                                                                                     |  |                                                                                    
|2492 Walnut Avenue, Suite 100
        Tustin, California 92780-7039
        (Address of principal executive offices) |  | (714) 505-4460
        (Registrant’s telephone number,
        including area code)



Securities registered pursuant to Section
12(b) of the Act:



|Title of each class            |  | Name of each exchange on which registered
|------------------------------ |  | -----------------------------------------
|Common Stock, $0.001 par value |  | OTCQB                                    



Securities registered pursuant to Section
12(g) of the Act:



Common Stock, $0.001 par value

(Title of class)



Indicate
by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act YesoNox



Indicate
by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act. YesoNox



Indicate
by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange
Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports),
and (2) has been subject to such filing requirements for the past 90 days. YesxNoo



Indicate
by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive
Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the
preceding 12 months (or for such shorter period that the registrant was required to submit and post such files). YesoNoo



Indicate
by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein, and will not be
contained, to the best of registrant’s knowledge, in definitive proxy or information statements incorporated by reference
in Part III of this Form 10-K or any amendment to this Form 10-K.o



Indicate by check mark
whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company.
See the definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company”
in Rule 12b-2 of the Exchange Act. (Check one):



|Large accelerated filero                      | Accelerated filero        
|--------------------------------------------- | --------------------------
|                                              |                           
|Non-accelerated filero                        | Smaller reporting companyx
|(Do not check if a smaller reporting company) |                           



Indicate
by check mark whether the registrant is a shell company (as defined in Exchange Act Rule 12b-2). YesoNox



The aggregate market
value of common stock held by non-affiliates of the Registrant on June 30, 2011 based on the closing price on that date of $4.88
on the OTC Market was approximately $21.1 million. For the purposes of calculating this amount only, all directors and executive
officers of the Registrant have been treated as affiliates. There were 1,347,936,151 shares of the Registrant’s common stock
outstanding as of June 15, 2012.



Documents Incorporated by Reference



None.











TABLE OF CONTENTS



|         |            |                                                                                                              |  | Page |    
|-------- | ---------- | ------------------------------------------------------------------------------------------------------------ |  | ---- | ---
|Part I   |            |                                                                                                              |  |      |    
|         | Item 1.    | Business                                                                                                     |  |      | 4  
|         | Item 1A.   | Risk Factors                                                                                                 |  |      | 12 
|         | Item 1B.   | Unresolved Staff Comments                                                                                    |  |      | 20 
|         | Item 2.    | Properties                                                                                                   |  |      | 21 
|         | Item 3.    | Legal Proceedings                                                                                            |  |      | 21 
|         | Item 4.    | Mine Safety Disclosure                                                                                       |  |      | 25 
|Part II  |            |                                                                                                              |  |      |    
|         | Item 5.    | Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities |  |      | 26 
|         | Item 6.    | Selected Financial Data                                                                                      |  |      | 35 
|         | Item 7.    | Management’s Discussion and Analysis of Financial Condition and Results of Operations                        |  |      | 35 
|         | Item 7A.   | Quantitative and Qualitative Disclosures About Market Risk                                                   |  |      | 48 
|         | Item 8.    | Financial Statements                                                                                         |  |      | 48 
|         | Item 9.    | Changes in and Disagreements with Accountants on Accounting and Financial Disclosure                         |  |      | 112
|         | Item 9A.   | Controls and Procedures                                                                                      |  |      | 112
|         | Item 9B.   | Other Information                                                                                            |  |      | 115
|Part III |            |                                                                                                              |  |      |    
|         | Item 10.   | Directors, Executive Officers, and Corporate Governance                                                      |  |      | 115
|         | Item 11.   | Executive Compensation                                                                                       |  |      | 118
|         | Item 12.   | Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters               |  |      | 121
|         | Item 13.   | Certain Relationships and Related Transactions, and Director Independence                                    |  |      | 123
|         | Item 14.   | Principal Accountant Fees and Services                                                                       |  |      | 124
|Part IV  |            |                                                                                                              |  |      |    
|         | Item 15.   | Exhibits, Financial Statement Schedules                                                                      |  |      | 126
|         | SIGNATURES |                                                                                                              |  | 132  |    



Page 2 of 132







Cautionary Statement under the Private
Securities Litigation Reform Act of 1995:



This Annual Report on Form 10-K and
the documents incorporated by reference herein contain forward-looking statements within the meaning of Section 21E of the Securities
Exchange Act of 1934, which include information relating to future events, future financial performance, strategies, expectations,
competitive environment, regulation and availability of resources. From time to time, we also provide forward-looking statements
in other materials we release to the public as well as verbal forward-looking statements. These forward-looking statements include,
without limitation, statements regarding: regulatory approval for our products; market demand for our products and competition;
our dependence on licensees, distributors and management; impact of technological changes on our products; results of operations
or liquidity; statements concerning projections, predictions, expectations, estimates or forecasts as to our business, financial
and operational results and future economic performance; and statements of management’s goals and objectives and other similar
expressions. Such statements give our current expectations or forecasts of future events; they do not relate strictly to historical
or current facts. Given these uncertainties, readers are cautioned not to place undue reliance on such forward-looking statements.
Words such as “may,” “will,” “should,” “could,” “would,” “predicts,”
“potential,” “continue,” “expects,” “anticipates,” “future,” “intends,”
“plans,” “believes,” “estimates,” and similar expressions, as well as statements in future
tense, identify forward-looking statements.



We cannot guarantee that any forward-looking
statement will be realized, although we believe we have been prudent in our plans and assumptions. Achievement of future results
is subject to risks, uncertainties and potentially inaccurate assumptions. Many events beyond our control may determine whether
results we anticipate will be achieved. Should known or unknown risks or uncertainties materialize, or should underlying assumptions
prove inaccurate, actual results could differ materially from past results and those anticipated, estimated or projected. You should
bear this in mind as you consider forward-looking statements.



We undertake no obligation to publicly
update or revise forward-looking statements, whether as a result of new information, future events or otherwise. You are advised,
however, to consult any further disclosures we make on related subjects in our Form 10-Q and 8-K reports to the SEC. Also note
that we provide the following cautionary discussion of risks, uncertainties and possibly inaccurate assumptions relevant to our
business. These factors individually or in the aggregate, we think could cause our actual results to differ materially from expected
and historical results. You should understand that it is not possible to predict or identify all such factors. Our actual results
may differ materially from those currently anticipated and expressed in such forward-looking statements as a result of a number
of factors, including those we discuss under “Risk Factors” and elsewhere in this Annual Report on Form 10-K.



Page 3 of 132







PART I



Item 1.Business



Recently, we have been experiencing severe
working capital shortages. Additionally, substantially all of the holders of approximately $14.0 million of our notes and redeemable
preferred shares had previously declared defaults and demanded repayment of these obligations, which we were unable to pay.



On May 15, 2012, we completed an agreement
with the 2011 Noteholders, severally and not jointly, for the exercise of an aggregate of $150,000 worth of our Series A Common
Stock Purchase Warrants at an exercise price of $0.02619 per share (the “May Agreement”). The proceeds received from
such Warrant exercise, shall be used solely and exclusively to enable us to keep our Registration Statement on Form S-1 filed under
the Securities Act of 1933, as amended, which the Securities and Exchange Commission declared effective on February 14, 2012, current
and maintain compliance with our reporting requirements under the Securities Exchange Act of 1934, as amended.



As a condition to the exercise of the Warrants,
we agreed that following the date of the May Agreement and through and including 5:00 p.m. (EDT) on August 31, 2012, we will not
file in any U.S. Bankruptcy Court a voluntary petition for reorganization under Chapter 11 of Title 11 of the United States Code
or seek to liquidate under Chapter 7 of such Code. Additionally, each of the 2011 Noteholders, severally and not jointly, agreed
to forebear from exercising any of their rights and remedies, whether at law or in equity, against us and our current and former
directors and officers for a period that shall not exceed the earlier to occur of (i) August 31, 2012, or (ii) a breach by us of
any of our other covenants and agreements contained in the prior agreements with the 2011 Noteholders or in the current Agreement,
including, without limitation, our commitment to file with the SEC our 2011 Form 10-K by June 30, 2012 and our March 31, 2012 Form
10-Q by July 15, 2012. The 2011 Noteholders further agreed that in the absence of a further breach of the terms of the May Agreement
or any of the other agreements between us and the 2011 Noteholders, that each of the previously issued default notices shall be
deemed to be withdrawn ab initio.



Accordingly, we are filing this Report
by such deadline and are vigorously working towards filing the 10-Q for the quarter ended March 31, 2012 timely as well. If we
breach this, or any other covenant, or breach any terms of our agreements with the 2011 Noteholders, we risk them re-establishing
their previous claims and defaults, which may cause us to cease operations, declare bankruptcy or take other actions that would
be terminate our business.



As of the date of this Report, we have
not entered into any formal arrangements, but continue to look for business transactions that will help us achieve revenue and
maintain our operations. However, without completing such a transaction or receiving any additional financing, we cannot guarantee
that we will be able to maintain operations.



As a result of our working capital
deficiencies, we have recently laid off a substantial portion of our work force and are currently operating on a minimal
basis with only two  employees and three former employee consultants. The current focus of our operations is to ensure that
our existing Onko-Sure® customers and any future customers are able to place orders and receive kits on a timely basis.
We have an Onko-Sure® production continuity arrangement in place with one vendor. At the current time, the Company
believes that it does not require any additional staff to perform this limited manufacturing, quality control and selling
process.



The Company appointed a committee of
three independent directors to assess available options open to the Company to enable us to continue operations. Due to the
shortage of working capital, we were unable to pay premiums associated with our Directors and Officers insurance. As
a consequence, on June 25, 2012, we were informed by two members of our Board of Directors of their resignation. As a result,
we have only one independent Director serving on our Board at this time. Although our remaining sales team continues to work
towards completing pending and future sales of our Onko-Sure ® test kit, if these sales are not completed and we do
not otherwise raise additional funds in the immediate future, it is likely that we will be forced to cease all operations
and might seek protection from our creditors under the United States bankruptcy laws.



We manufacture our proprietary Onko-Sure®
cancer test kits at our licensed manufacturing facility located at 2492 Walnut Avenue, Suite 100, in Tustin, California. We are
an FDA approved Good Manufacturing Practices manufacturing facility. We maintain a current Device Manufacturing License issued
by the State of California, Department of Health Services, Food and Drug Branch.



We are engaged in the research, development,
manufacturing, sale and marketing of our Onko-Sure ® test kit, which is a proprietary in-vitro diagnostic (or IVD) cancer test.
We market our Onko-Sure®test kits in the United States, Canada, Chile, Europe, India, Korea, Japan, Taiwan, Vietnam
and other markets throughout the world. Our product is sold either directly to Clinical Laboratory Improvement Amendments (“CLIA”)
certified reference laboratories or to third party distributors, who then resell to CLIA certified reference laboratories in the
United States as well as clinical reference labs, hospital laboratories and physician operated laboratories in the international
market.



Page 4 of 132







Our Onko-Sure®IVD test enables
physicians and their patients to detect and/or monitor the treatment/recurrence of solid tumors by measuring the accumulation of
specific breakdown products in the blood called Fibrin and Fibrinogen Degradation Products (FDP). Onko-Sure® is a simple, non-invasive
blood test designed to be used for the detection and/or monitoring of 19 different types of cancer including: lung, breast, tongue,
stomach, liver, colon, rectal, bladder, brain, hematological, prostate, ovarian, esophageal, cervical, uterine, liver, trophoblastic,
thyroid, malignant lymphoma, and pancreatic cancers. We believe that Onko-Sure® can be a valuable diagnostic tool in the worldwide
battle against cancer. Because the Onko-Sure® test kit is a non-invasive blood test, there are no side effects of the administration
of the test. As with other cancer diagnostic products, false positive and false negative test results could pose a small risk to
patient health if the physician is not vigilant in following up on the Onko-Sure® test kit results with other clinically relevant
diagnostic modalities. While the Onko-Sure®, like other blood biomarker tests, could be helpful in cancer detection, the attending
physician is required to use other testing methods to confirm the type of cancer.



Onko-Sure® is sold as a blood test
for cancer in Europe (CE Mark certified), India, Japan, Taiwan, Korea, Vietnam, and in Chile (research use). In the United States,
it is cleared by the Food and Drug Administration (FDA) for the monitoring of colorectal cancer treatment and recurrence, and is
approved in Canada (by Health Canada) for lung cancer detection and treatment/recurrence monitoring. We believe that Onko-Sure®
has the potential to be used as a general cancer screening test. We are involved with research conducted with CLIA laboratories
to expand on the clinical utility of Onko-Sure®.



We manufacture and distribute our cancer
test kits at our licensed manufacturing facility located at 2492 Walnut Avenue, Suite 100, in Tustin, California. We are a United
States Food and Drug Administration (“FDA”), “good manufacturing practices” compliant facility. We maintain
a current Device Manufacturing License issued by the State of California, Department of Health Services, Food and Drug Branch.



On September 25, 2009, we changed our corporate
name from “AMDL, Inc.” to Radient Pharmaceuticals Corporation.



On November 4, 2011, the Company filed
a Certificate of Amendment of its Amended and Restated Certificate of Incorporation to increase its authorized common stock shares
to 5 billion and preferred stock shares to 25 million. In addition, the Company affected a reverse stock split of the Company’s
issued and outstanding shares of common stock at a ratio of 1:25 (the “Reverse Split”).  The Reverse Split
provides that each twenty-five (25) outstanding shares of the Corporation’s common stock, par value $0.001 per share, will
be exchanged and combined, automatically, without further action, into one (1) share of common stock. The Reverse Split was
declared effective on February 10, 2012 by FINRA and has been retroactively reflected in the Company’s December 31, 2011
Annual Report on Form 10-K.



IVD DIAGNOSTICS DIVISION



IVD Industry and Market



During fiscal 2011 and 2010, we had three
and four customers which represented approximately 64% and 94% of our net revenues, respectively. For the year ended December 31,
2011 and 2010, two customers were based in the U.S. and represented approximately 42% and 59% of our net revenues and one and three
customers were based outside the US and represented approximately 22% and 35% of our net revenues, respectively.



Below is a table showing our major customers and percentage
of sales for each:







|              |  |          |    | % of Net Revenues |   
|------------- |  | -------- | -- | ----------------- | --
|Customer      |  | Location |    | 2011              |   
|A             |  | US       |    |                   | 19
|B             |  | US       |    |                   | 23
|Total US      |  |          |    |                   | 42
|              |  |          |    |                   |   
|C             |  | Vietnam  |    |                   | * 
|D             |  | Taiwan   |    |                   | * 
|E             |  | Korea    |    |                   | 22
|              |  |          |    |                   |   
|Total Foreign |  |          | 22 | %                 |   










|* | less than 10% of net revenues
|- | -----------------------------





Page 5 of 132







On July 3, 2008 we received a determination
letter from the USFDA approving our application to market Onko-Sure® test kit as an immunology and microbiology device to monitor
colorectal cancer under the category “Tumor Associated Antigens Immunological Test System” as a Class II IVD device.
The receipt of United States Food and Drug Administration (“USFDA”) clearance for marketing our proprietary Onko-Sure®
cancer test kit in July 2008 has given us significant visibility in the in-vitro diagnostics (“IVD”) industry. The
growth of the IVD marketplace has been driven by an increase in the incidence of cancer, other chronic and infectious diseases,
emerging technologies and increasing patient awareness. Cancer testing is one of the most important growth opportunities for the
next three to five years in the diagnostics segment. The National Cancer Institute estimates that about ten million Americans have
or have had some form of cancer. Overall costs of the disease are $126 billion annually. (Cancer Diagnostic Testing World Markets,
July 2011,www.reportlinker.com/p089470-summary/Cancer-Diagnostic-Testing-World-Markets.html).



Onko-Sure®



In clinical trials, the Onko-Sure®
test kit has demonstrated its ability to detect the presence of certain cancers in humans with a high sensitivity between 50% -
100% and specificity between 57% - 100%. Onko-Sure® is a simple, non-invasive blood test used for the detection and/or monitoring
of the presence of certain cancers, including: colon, rectal, lung, stomach, tongue, ovarian, uterine, liver, pancreatic, bladder,
brain, esophageal, hematological, breast, prostate, cervical, thyroid, lymphoma and trophoblast cancers. A positive Onko-Sure®
value is followed with other diagnostic tests to determine the specific type of cancer. Onko-Sure® can be a valuable diagnostic
tool in the worldwide battle against cancer, the second leading cause of death worldwide.



The Onko-Sure® test kit is a tumor-marker,
which is a biochemical substance indicative of neoplasia, potentially specific, sensitive, and proportional to tumor load, used
to screen, diagnose, assess prognosis, follow response to treatment, and monitor for recurrence. As Onko-Sure® test kit is
a non-invasive blood test, there are no side effects of the administration of the test. As with other cancer diagnostic products,
false positive and false negative test results could pose a small risk to patient health if their physician is not vigilant in
following up on the Onko-Sure® test kit results with other clinically relevant diagnostic modalities. While the Onko-Sure®
test kit is helpful in diagnosing whether a patient has cancer, the attending physician needs to use other testing methods to determine
and confirm the type and kind of cancer involved.



The Onko-Sure® test kit can be added
easily and inexpensively to the pre-existing line of ELISA-based diagnostics performed routinely by clinical laboratories throughout
the world. Furthermore, the Onko-Sure® test kit can be used in place of more costly and time consuming diagnostic tests. In
clinical trials in U.S., China, Germany, Taiwan and Turkey, Onko-Sure® has been used as a screen for multiple cancers while
only needing a single blood sample.



Our Onko-Sure® test kits are currently
sold in the form of a 96 well test plate, which, after standards are applied, 41 individual tests can be run in duplicate. These
tests are typically run in a reference laboratory with test results determined by using a micro-titer reading analyzer. Results
are sent to the attending physician who then relays those results to the patient. Typically, a patient can receive results within
3-5 days from the blood draw date.



Onko-Sure® Test Kit Sales and Distribution Strategy



On July 8, 2009, we changed the brand name
of ourin-vitro diagnostic cancer test fromDR-70TMto our trademarked brand name “Onko-Sure®,”
which we believe is more consumer friendly and communicates it as a high quality, innovative consumer cancer test. We also installed
a new tag line — “The Power of Knowing” — which communicates to cancer patients and their physicians that
the test is effective in assessing whether a patient’s cancer is progressing during treatment or is in remission.



We market our Onko-Sure® cancer test
kits through third party distributors, who then resell directly to CLIA certified reference laboratories in the United States,
as well as to clinical reference labs, hospital laboratories and physician operated laboratories in international markets. We are
seeking to engage additional distributors who will sell to reference and clinical laboratories in the U.S., and other countries
to make the Onko-Sure® test kit available to physicians and patients. Our objectives regarding the development, marketing and
distribution of our Onko-Sure® test kit are to:



Page 6 of 132









| | · | obtain international approvals;
| | - | -------------------------------



| | · | develop new distribution channels in new
market;
| | - | ------------------------------------------------



| | · | distribute greater quantities of kits
in approved markets;
| | - | ----------------------------------------------------------



| | · | fully utilize our GMP manufacturing facilities
in the U.S. to foster worldwide sales;
| | - | -------------------------------------------------------------------------------------



| | · | automate the Onko-Sure® test kit;
and
| | - | -------------------------------------



| | · | eventually create a “rapid test”
format of Onko-Sure® test kit to extend sales into rural areas and Physician Owned Labs (“POL”) .
| | - | ----------------------------------------------------------------------------------------------------------------------------------





As of December 31, 2011, we had entered into the following distribution
agreements:



| | 1. | An exclusive five-year distribution agreement with Grifols USA, LLC (“Grifols”). This
distribution agreement allows Grifols USA, LLC to market and sell Onko-Sure® for the monitoring of colorectal cancer to hospitals,
clinical laboratories, clinics and other health care organizations in the U.S. and Puerto Rico.
| | -- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | 2. | Four distinct exclusive five-year distribution agreements, one three-year distribution agreement,
and one two-year distribution agreement, with GenWay Biotech, Inc. (“GenWay”). These six distribution agreements allows
Genway to market and sell Onko-Sure® for uses other than colorectal cancer to CLIA-certified laboratories in the U.S. as a
lung cancer screen to laboratories in Canada, and the marketing and sales of Onko-Sure® in the United Kingdom, European Union,
the Middle East, Russia and Greece.
| | -- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | 3. | An exclusive five-year distribution agreement with Pharmaline Saglik Hzmetleri Tic (“Pharmaline”).
This distribution agreement allows Phamaline to market and sell Onko-Sure® in Turkey.
| | -- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | 4. | An exclusive five-year distribution agreement with Jaiva Guar Diagno (“Jaiva GD”).
This distribution agreement allows Jaiva GD to market and sell Onko-Sure® in India.
| | -- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | 5. | An exclusive five-year distribution agreement with AMDL Australia PTY Ltd. (“AMDL Australia”).
This distribution agreement allows AMDL Australia to market and sell Onko-Sure® in Australia and New Zealand.
| | -- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | 6. | An exclusive five-year distribution agreement with Phu Gia Trading Co. Ltd. (“Phu Gia”).
This distribution agreement allows Phu Gia to market and sell Onko-Sure® in Vietnam, Laos, and Cambodia.
| | -- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | 7. | An exclusive five-year distribution agreement with Bio-Asia Diagnostics Co. Ltd. (“Bio-Asia”).
This distribution agreement allows Bio-Asia to market and sell Onko-Sure® exclusively in Hong Kong and non-exclusively for
research use only in China.
| | -- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | 8. | An exclusive five-year distribution agreement with Uni-Pharma Taiwan (“Uni-Pharma”).
This distribution agreement allows Uni-Pharma to market and sell Onko-Sure® in Taiwan, Singapore, and Hong Kong/Macau.
| | -- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | 9. | An exclusive five-year distribution agreement with TS Pharm Inc. (“TS Pharm”). This
distribution agreement allows TS Pharm to market and sell Onko-Sure® in Caribbean Region.
| | -- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------





Page 7 of 132









| | 10. | A non-exclusive five-year distribution agreement with Omnimed Inc. (“Omnimed”). This
distribution agreement allows Omnimed to market and sell Onko-Sure® in South Korea.
| | --- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | 11. | A non-exclusive five-year distribution agreement with Naroo Ditech Inc. (“Naroo”).
This distribution agreement allows Naroo to market and sell Onko-Sure® in Korea.
| | --- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------



In all of our exclusive distribution agreements,
the distributor is required to purchase a minimum number of Onko-Sure® test kits during each quarter of the agreement to maintain
their exclusivity rights in their assigned territories.



If minimum purchase requirements are not
met, we maintain the right to convert the exclusive agreement into a non-exclusive agreement. The distributor is not legally bound
to meet the minimums and in most cases, failure to meet the minimum does not constitute a breach of contract.



During the year ended December 31, 2011, our exclusive distributors
did not meet the minimum purchase requirements.



There may be factors that prevent us from
further developing and marketing the Onko-Sure® test kit. We cannot guarantee the Onko-Sure® test kit will be commercially
successful in either the U.S. or internationally. Clinical trials results are frequently susceptible to varying interpretations
by scientists, medical personnel, regulatory personnel, statisticians and others, which may delay, limit or prevent further clinical
development or regulatory approvals of a product candidate. Also, the length of time that it would take for us to complete clinical
trials and obtain regulatory approval for product marketing may vary by product and by the intended use of a product. We cannot
predict the length of time it would take to complete necessary clinical trials and obtain regulatory approval in any other country.



Competition



We have only had limited sales of Onko-Sure®
test kit to our distributors both inside and outside the United States. We are dependent on our distributors’ financial ability
to advertise and market the Onko-Sure® test kit. A number of domestic and international companies are in indirect competition
with us in all of these markets. Most of these companies are larger, more firmly established, have significant marketing and development
budgets and have greater capital resources than us or our distributors. Therefore, there can be no assurance that we will be able
to achieve and maintain a competitive position in the diagnostic test industry.



Many major medical device manufacturers,
including Abbott Diagnostics, Baxter Healthcare Corp., Beckman Diagnostics, Boehringer Mannheim, Centocor, Diagnostic Products
Corporation, Bio-Rad Laboratories, Roche Diagnostic Systems, Sigma Diagnostics and others, are manufacturers or marketers of other
diagnostic products. We are not aware of any efforts currently being devoted to development of products such as our Onko-Sure®
test kit; however, there can be no assurance that such efforts are not being undertaken without our knowledge. We believe that
most of the diagnostic products currently manufactured by other companies are complementary to our Onko-Sure® test kit. Moreover,
such companies could develop products similar to our products and they may be more successful in marketing and manufacturing their
products. In addition, there are a number of new technologies in various stages of development at the National Institute of Health,
university research centers and at other companies for the detection of various types of cancers, e.g., identification of proteomic
patterns in blood serum that distinguishes benign from cancerous conditions, which may compete with our product.



Manufacturing



We manufacture our Onko-Sure® test
kit at our licensed manufacturing facility located at 2492 Walnut Avenue, Suite 100, in Tustin, California.



In December 2003, our product Onko-Sure®
(also known as AMDL-ELISA DR-70(FDP)) obtained the CE marking approval (the “CE Certificate”) allowing it to be marketed
in the European Economic Area (“EEA”). We were issued an “EN ISO 13485:2003 + AC:2007” certificate on September
12, 2008.



In November 2004, the USFDA inspected our
facilities with six observations listed on the issued FDA-483 Warning Letter. On July 2, 2008, we were audited by TUV Rheinland
for ISO 13485 compliance and one observation was reported on the audit report. On May 20, 2008, we were audited by California Department
of Public Health (“CDPH”) which is an independent entity from FDA. We are in compliance with both the USFDA and CDPH
as of the date of this Report.



Page 8 of 132







Regulatory Approval and Clinical Trials



The Onko-Sure® test kit is subject
to specific USFDA rules applicable to IVD products. Prior to marketing Onko-Sure® test kit in the U.S., we were required to
make a pre-market application to prove the safety and efficacy of the products and to comply with specified labeling requirements
for IVD products for human use. We received a determination letter on July 3, 2008 from the USFDA approving our application to
market Onko-Sure® test kit as an immunology and microbiology device to monitor colorectal cancer under the category “Tumor
Associated Antigens Immunological Test System” as a Class II IVD device. USFDA clearance to market was based upon data showing
that the Onko-Sure® test kit has the ability to monitor the progression of colorectal cancer post-surgery in patients who are
biopsy confirmed with this disease. This announcement marks the first clearance to market a colorectal monitoring product that
the USFDA has granted since January 14, 1982 when Carcinoembryonic Antigen (CEA) was approved. Until now, the CEA test has been
the only accepted method cleared in the U.S. Thus, Onko-Sure® test kit offers a new test that can monitor colorectal tumors
post-surgery.



We must abide by the listing rules of the
USFDA. We have established our Quality System Regulation in accordance with applicable regulations and were most recently inspected
in July 2008. Our Quality System Regulation program contains applicable complaint provisions that we believe meet the USFDA’s
requirements for Medical Device Reporting, and we have experienced no incidents or complaints to date. We also implemented procedures
for preventive and corrective action and changed our packing and shipping method once in 2002 to improve the protection of our
product.



We have a limited supply of the horseradish
peroxidase (“HRP”)-conjugated anti-fibrin and fibrinogen degradation (“FDP”) antibody component currently
used for the approved Onko-Sure® test kit. Because of the limited supply of the current antibody, we have determined it is
in our best interest to change to a HRP-conjugated anti-FDP antibody.



We were screening six commercially available
conjugated antibodies to substitute into the current Onko-Sure® test kit and one we produced and conjugated ourselves. The
anti-FDP antibody we produced ourselves has performed well in pilot studies and will likely be used in our next generation Onko-Sure®
test kit. If the antibody substitution significantly improves Onko-Sure® test kit performance, we will be required to change
the reported sensitivity and specificity of the Onko-Sure® test kit. Because of these changes and modifications, we will likely
have to submit a new 510(k) premarket notification application, but can continue to sell the existing kit until our current antibody
supply is exhausted. If the new antibody does not significantly affect the clinical performance of the test, we can likely substitute
it into the currently approved kit without filing a new 510k.



In March 2011, the Company hired a post-Doctoral
Fellow and M.D. who formerly worked at the City of Hope Hospital to work on a project to purify the raw antibody serum the Company
had stored in order for it to be usable in its test kits.The Company has been able to optimize the antibody purification technique
to make an additional 12,000 test kits. When the raw antibody serum the Company has on-hand is purified it will make approximately
94,000 test kits. In addition, our test kits require anti-fibrinogen HRP of which we have a limited quantity. Due to the lack of
funds, we suspended the project of investigating alternatives or outsourcing of the anti-fibrinogen HRP to be used in our test
kits. Currently, we have two lots remaining which are estimated to produce approximately 21,000 kits. In order to utilize in kits,
we will need to purify and quality control the lots. We currently have enough purified and quality checked anti-fibrinogen-HRP
to manufacture 200 kits. When funds are available, we will begin the quality control and purification process which will enable
us to increase our raw material inventory. Based on our current and anticipated orders, this supply is not adequate to fill all
such orders.



In addition to the USFDA regulation and
approval process, each foreign jurisdiction may have separate and different approval requirements and processes. Our distribution
agreements require our distributors to obtain the requisite approval and clearance in each jurisdiction in which they sell products.
In our experience, once a foreign approval is obtained, it is generally renewed on a periodic basis, annually or otherwise. In
certain territories, distributors can sell under limited circumstances prior to approval and in other territories no formal approval
is required. On December 20, 2000, the Medical Devices Agency of United Kingdom Department of Health issued a letter of no objection
to the exportation of our Onko-Sure® test kit from the U.S. to the United Kingdom, allowing our Onko-Sure® test kit to
be sold in the United Kingdom. We have also received regulatory approval to market the Onko-Sure® test kit in South Korea and
import and market the Onko-Sure® test kit in Australia. In Canada, our Onko-Sure® test kit is approved as a screening device
for lung cancer only. Our Onko-Sure® test kit also has the CE mark from the European Union for sale in Europe as a general
cancer screen.



Page 9 of 132







Obtaining regulatory approval in the U.S.
for our Onko-Sure® test kit was costly, and it remains costly to maintain. The USFDA and foreign regulatory agencies have substantial
discretion to terminate clinical trials, require additional testing, delay or withhold registration and marketing approval and
mandate product withdrawals. In addition, later discovery of unknown problems with our products or manufacturing processes could
result in restrictions on such products and manufacturing processes, including potential withdrawal of the products from the market.
If regulatory authorities determine that we have violated regulations or if they restrict, suspend or revoke our prior approvals,
they could prohibit us from manufacturing or selling our products until we comply, or indefinitely.



In the U.S., we were required to make a
pre-market application to prove the safety and efficacy of the products and to comply with specified labeling requirements for
IVD products for human use. We received a determination letter on July 3, 2008 from the USFDA approving our application to market
Onko-Sure® test kit as an immunology and microbiology device to monitor colorectal cancer under the category “Tumor Associated
Antigens Immunological Test System” as a Class II IVD device. USFDA clearance to market was based upon data showing that
the Onko-Sure® test kit has the ability to monitor the progression of colorectal cancer post-surgery in patients who are biopsy
confirmed with this disease. This announcement marks the first clearance to market a colorectal monitoring product that the USFDA
has granted since January 14, 1982 when Carcinoembryonic Antigen (CEA) was approved. Until now, the CEA test has been the only
accepted method cleared in the U.S. Thus, Onko-Sure® test kit offers a new test that can monitor colorectal tumors post-surgery.



Onko-Sure® Test Kit Research and Development



During the years ended December 31, 2011
and 2010, we incurred expenses of $115,476 and $673,918, respectively, in research and development costs related to the clinical
testing and study of our Onko-Sure® test kit.



Reimbursability of Our IVD Products



We recognize health care cost reimbursement
under private and government medical insurance programs is critical to gaining market share in any of the markets where we intend
to sell our IVD products. Due to the lack of funds, we suspended our program for reimbursement until additional funds are received.



CANCER THERAPEUTICS



Combination Immunogene Therapy



In 2001, we acquired the CIT technology,
which forms the basis for a proprietary cancer vaccine. Our CIT technology is a U.S. patented technology (patent issued May 25,
2004). The Cancer Therapeutics division is engaged in commercializing the CIT technology. To date, we have not generated any revenues
and incurred expenses mostly related to patent protection and license fees, for this technology. As of December 31, 2010, we fully
impaired the value of our intangible asset related to this technology.



On February 22, 2002, AcuVector Group,
Inc. (“AcuVector”) filed a Statement of Claim in the Court of Queen’s Bench of Alberta, Judicial District of
Edmonton, Canada relating to our CIT technology acquired from Dr. Chang in August 2001. AcuVector, a former licensee of Dr. Chang,
claims that the license agreement between the parties is still in effect. AcuVector is seeking substantial damages and injunctive
relief against Dr. Chang for the effectiveness of the agreement and CDN$20,000,000 in damages against us for alleged interference
with the relationship between Dr. Chang and AcuVector. We performed sufficient due diligence at the time we acquired the technology
to permit us to conclude that AcuVector had no interest in the technology when we acquired it. We believe that the agreement between
AcuVector and Dr. Chang terminated, that AcuVector’s claims are without merit and that we will receive a favorable judgment.



We are also defending a companion case
filed in the same court by the Governors of the University of Alberta against us and Dr. Chang. The University of Alberta claims,
among other things, that Dr. Chang failed to remit the payment of the University’s portion of the monies we paid to Dr. Chang
for the CIT technology we purchased from Dr. Chang in 2001. In addition to other claims against Dr. Chang relating to other technologies
developed by him while at the University, the University also claims that we conspired with Dr. Chang and interfered with the University’s
contractual relations under certain agreements with Dr. Chang, thereby damaging the University in an amount which is unknown to
the University at this time. The University has not claimed that we are not the owner of the CIT technology, just that the University
has an equitable interest therein or the revenues there from.



Page 10 of 132







After being filed, the court approved an
order to dismiss the case. However, opposing counsel, who approved the form of order, filed an appeal on December 23, 2011 (see
Item 3. Legal Proceedings).



In February 2009, we submitted a Response
to Final Office Action in support of USPTO Application number 10/785,577 entitled “Combination Immunogene Therapy”
that was filed February 23, 2004. We have not received any further indication, or comments, from the USPTO as to the outcome of
our application, but remain optimistic about the likelihood of patent approval.



On April 1, 2010 we entered into an exclusive
5-year collaboration agreement with Jaiva Technologies, Inc. (“JTI”). JTI’s CEO is Dr. Umesh Bhatia. Under the
terms of the agreement, JTI will collaborate with clinical laboratories, hospitals and physicians in India to conduct clinical
trials for our CIT technology. Additionally, Jaiva will support us in securing Indian government approval for the use of the CIT
technology as a cancer therapy and vaccine throughout the country.



In December 2010, we formed NuVax Therapeutics,
Inc. (“NuVax”) with Javia’s CEO Dr. Umesh Bhatia by creating a platform to expand the planned collaboration to
include significantly expanded clinical trials in multiple international locations and in the U.S., and the in-licensing of other
novel cancer fighting technologies. All rights to our CIT technology will be transferred to NuVax, currently our 100% wholly-owned
subsidiary. All further development and commercialization of CIT and other to-be licensed novel cancer fighting technologies will
be made at NuVax.



Due to the following conditions at December 31, 2010, we decided
to impair the remaining balance of our CIT asset:



| | · | Lack of any potential future revenue;    
| | - | -----------------------------------------
| | · | Lack of future cash flows;               
| | · | High cost of future clinical studies; and
| | · | Limited time remaining on the patent.    



The amount of the impairment was $1,058,333
for the year ended December 31, 2010.



In January 2011, NuVax signed four exclusive
license agreements with the University of Florida Research Foundation, Inc. (“UFRF”), for the development and marketing
of a cancer therapeutic product developed by the UFRF. In July 2011, the UFRF terminated the agreements due to lack of funding.



On August 29, 2011, due to lack of funding
and activity, Umesh Batia resigned as CEO and Director of NuVax. As of the date of this report, we have not generated any revenues
and incurred license termination fees expenses for NuVax. Until we can complete funding for NuVax, we will continue to have minimal
activity in NuVax.



OUR ONKO-SURE® PATENTS



Success in development of our Onko-Sure®
patents depends, in part, on our ability to obtain U.S. and foreign patent protection for our products, preserve our trade secrets,
and operate without infringing upon the proprietary rights of third parties.



The U.S. Patent and Trademark Office (“USPTO”)
has issued to us two patents which describe methods for measuring ring-shaped particles in extra-cellular fluid as a means for
detecting cancer. Our patent for a method of detecting the tumors using ring shaped particles as a tumor marker was issued on October
17, 1995 and expires on October 17, 2012.



Our patent for a method for detecting the
presence of ring shaped particles as tumor markers was issued on June 3, 1997 and expires on June 3, 2014.



We have three additional patent applications
pending in the U.S. with respect to our methodology for the Onko-Sure® tumor-markers as reliable indicators of the presence
of cancer. In addition, we have one patent based on our methodology for the Onko-Sure® tumor marker pending in Europe.



Page 11 of 132







There can be no assurance however, that
any additional patents will be issued to us, or that, if issued, the breadth or degree of protection of these patents will be adequate
to protect our interests. In addition, there can be no assurance that others will not independently develop substantially equivalent
proprietary information or obtain access to our know-how. Further, there can be no assurance that others will not be issued patents
which may prevent the sale of our test kits or require licensing and the payment of significant fees or royalties by us in order
for us to be able to carry on our business. Finally, there can be no guarantee that any patents issued to or licensed by us will
not be infringed by the products of others. Defense and prosecution of patent claims can be expensive and time consuming, even
in those instances in which the outcome is favorable to us. If the outcome is adverse, it could subject us to significant liabilities
to third parties, require us to obtain licenses from third parties or require us to cease research and development activities or
sales.



EMPLOYEES



As of December 31, 2011, we had 11 full-time
employees in the U.S. We supplement our permanent staff with temporary personnel. Our employees are neither represented by a union
nor subject to a collective bargaining agreement, and we consider our relations with our employees to be favorable. We have entered
into certain agreements with our employees regarding their services. We utilize the services of consultants for safety testing,
regulatory and legal compliance, and other services. As of the date of this Report, due to the lack of funding, all but two employees
have been laid-off while the remaining staff has been retained on a “as needed” consulting basis. Such consultants
get paid an hourly rate for hours worked.



EXECUTIVE OFFICES



Our executive offices are located at 2492
Walnut Avenue, Suite 100, Tustin, California 92780, telephone number (714) 505-4460.



Available Information



We are subject to the informational requirements
of the Securities Exchange Act of 1934 and, in accordance therewith, file reports and other information with the SEC. Our reports
and other information filed pursuant to the Securities Exchange Act of 1934 may be inspected and copied at the public reference
facilities maintained by the SEC at 100 F Street, N.E., Washington, D.C. 20549. Copies of such material can also be obtained from
the Public Reference Room of the SEC at 100 F Street, N.E., Washington, D.C. 20549, at prescribed rates. The public may obtain
information on the operation of the Public Reference Room by calling the SEC at 1-800-SEC-0330. In addition, the SEC maintains
a website that contains reports and other information regarding registrants that file electronically with the SEC. The address
of the SEC’s Web site is http://www.sec.gov.



Although we maintain a website, www.radient-pharma.com,
we do not post our annual report on Form 10-K or other periodic reports there. However, we provide a link to our SEC filings on
our website and you can request copies of such reports from our investor relations team and they will submit them to you free of
charge. You can contact our investor relations team at ir@radient-pharma.com or by telephone at 714-505-4460.



Information located on, or accessible through,
our website is not incorporated into this filing unless this filing specifically indicates otherwise.



Item 1A. Risk Factors



Our business involves significant risks which are described
below.



Risks Related to our Financial Condition



Our independent registered public
accounting firm has included a going concern and “emphasis of a matter” paragraph in their report on our financial
statements.



Our independent registered public accounting
firm expressed an opinion on our consolidated financial statements which includes an explanatory paragraph indicating that there
is substantial doubt about our ability to continue as a going concern due to our significant operating loss in 2011, our negative
cash flows from operations through December 31, 2011 and our accumulated deficit at December 31, 2011. Our ability to continue
as an operating entity currently depends, in large measure, upon our ability to generate additional capital resources. The opinion
also includes an “emphasis of a matter” paragraph which refers to our default on debt described in Note 16 to the consolidated
financial statements. While we seek ways to continue to operate by securing additional financing resources or alliances or other
partnership agreements, we do not at this time have any commitments or agreements that provide for additional capital resources.
Our financial condition and the going concern emphasis paragraph may also make it more difficult for us to maintain existing customer
relationships and to initiate and secure new customer relationships.



Page 12 of 132







We have incurred significant losses
and may never generate profits.



We incurred net losses of $86,187,269 and
$85,711,853 for the fiscal years ended December 31, 2011 and 2010, respectively, had an accumulated stockholder deficit of $224,337,675
at December 31, 2011. In addition to operational expenses, we incurred significant charges related to interest expense, losses
from the extinguishment of debt, loss on legal settlement and loss on guarantee, offset by net gain on change in fair value of
derivative liabilities contributed to the increase in our accumulated losses and stockholders’ deficit during the year ended
December 31, 2011. There can be no assurance that we will ever be able to achieve our sales goals or earn a profit.



We require significant additional
working capital to conduct our business and maintain our operations.



The current level of our revenues is not
sufficient to finance our operations on a long-term basis. The $150,000 of net proceeds we received in May pursuant to the letter
agreement with the 2011 Noteholders shall only be used to keep our Registration Statement on Form S-1 filed under the Securities
Act of 1933, as amended, which the Securities and Exchange Commission declared effective on February 14, 2012, current and maintain
compliance with our reporting requirements under the Securities Exchange Act of 1934, as amended At June 15, 2012, we had cash
on hand of approximately $3,000.



Due to the lack of funding, the Company
suspended most research and development, marketing as well as incurred a reduction in work force. As a result, the Company currently
requires approximately $40,000 per month for operating expenses to fund the costs associated with our SEC reporting; general and
administrative expenses; regulatory compliance, and distribution activities related to our Onko-Sure® test kit and the operation
of a USFDA approved pharmaceutical manufacturing facility. Based on our current cash position and without additional financing
we have been unable to pay all our obligations.



The monthly cash requirement for operating
expenses does not include payments for legal, consulting, certain general and administrative expenses and accounting as well as
any extraordinary items or expenditures, payments for research on clinical trials for our Onko-Sure® test kit, and research
conducted through CLIA Laboratories.



Accordingly, if we do not receive additional
financing, we will be unable to increase or maintain our current sales of our Onko-Sure® IVD test kits or otherwise support
our operating cash needs. We have suspended most activities except those that are required to preserve the Corporate entity. However,
if additional funding is not obtained or we have an increase in sales, we may no longer be able to pay our continuing obligations
when due or to continue to operate our business.



As a result, we might be required to cease
operations or seek protection under the U.S. bankruptcy laws.



We are relying upon investors exercising
our Series A Warrants for cash to obtain needed additional financing.



We registered 16,000,000 Series A Warrant
Shares, or only 5.1% of the 313,500,000 shares of common stock initially issuable under the Series A Warrant, under the registration
statement that was made effective on February 14, 2012. We may also register for resale in future registration statements additional
Series A Warrant Shares, to the maximum extent permitted by the SEC under Rule 415. We require significant additional working capital
to continue our business operations, and are relying largely upon the cash exercise of the Series A Warrants to provide such additional
working capital. There can be no assurance that we will be able to register sufficient Series A Warrant Shares for resale or that,
even if registered, that the holders of the Series A Warrants will elect to exercise all or any portion thereof for cash. . Pursuant
to the May 2012 agreement with these warrant holders, $150,000 worth of such warrants were exercised. Even if all remaining 10,272,624
Series A Warrant Shares are exercised for cash, at the adjusted exercise price of $0.05 per share, we will only receive approximately
$800,000 in proceeds. As of the date of this report, 5,727,346 Series A Warrants were exercised at the adjusted exercise price
of $0.02619. Proceeds were used to pay a portion of legal, accounting and consulting fees necessary to complete our SEC filings.



Page 13 of 132







We have a significant amount of indebtedness
that is in default and we are currently unable to satisfy our obligations to pay interest and principal thereon.



As of June 15, 2012, we had the following
approximate amounts of outstanding short term indebtedness:



| | · | Accrued interest of approximately $1,054,088;
| | - | ---------------------------------------------



| | · | Approximately $46,000 in unsecured convertible
notes bearing interest at 10% per annum increased to 18% per annum due to failure to pay the Notes by September 29, 2010;
| | - | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | Approximately
$25,000 in senior unsecured convertible promissory notes bearing interest at 18% interest, payable quarterly in cash, which became
due between December 2010 and May 2011;
| | - | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | Approximately
$8.0 million in legal settlement promissory notes, bearing interest at 8% per annum. We are obligated to retire the Notes in monthly
installments, commencing January 31, 2012, by payment in cash or (at our sole option) by delivery of shares of our common stock
in an amount equal to 6.25% of the initial principal amount of each Note, plus accrued interest;
| | - | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | Approximately $4.8 million in outstanding
November Notes and $3.4 million in Series B and $500,000 Series C convertible preferred stock which, unless converted into our
common stock, matures or is subject to mandatory redemption on November 29, 2012; and
| | - | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------





| | · | Approximately $300,000 in unsecured
                                                                                                          convertible notes bearing interest at 4% per annum that matures on April 30, 2015.
| | - | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Absent full conversion of these debts or
the receipt of new financing or series of financings, our current operations do not generate sufficient cash to pay these obligations,
when due. Accordingly, there can be no assurance that we will be able to pay these or other obligations which we may incur in the
future.



In the event we are unable to convert into
equity the balance of the outstanding November Notes, RDO Notes and the outstanding redeemable Series B and Series C Preferred
Stock, the holders may obtain judgments against us and seek to enforce such judgments against our assets, in which event we will
be required to cease our business activities and the equity of our stockholders will be effectively wiped out.



There are pending lawsuits against
us, which if decided in plaintiffs’ favor may result in the payment of cash damages, additional warrants, and liability for
certain of our executive officers.



On March 11, 2011, a class action suit
was filed against us, alleging we violated federal securities laws by misrepresenting the relationship between us and third parties
involved in our clinical studies of Onko-Sure® test. As of the date of this filing, we hired outside defense counsel, but have
not submitted our response to the complaint. We vehemently deny the allegations in the complaint and are proceeding to vigorously
defend the suit. Due to the uncertain nature of litigation and the early stage of this lawsuit, we cannot calculate the potential
damages – nor does the complaint seek any specific monetary amount of damages.



We have been engaged in
litigation with AcuVector and with the Governors of the University of Alberta over our CIT technology. Formal orders to
dismiss were filed and approved by the Court. However, opposing counsel, who approved the form of order, filed an appeal on
December 23, 2011. Although we believe both actions are without merit and that the dismissal order should be upheld, it is
possible the appeal will be granted and then, if either AcuVector or the University is successful in their claims, we may be
liable for substantial damages, our right to the technology will be adversely affected and our future prospects for
exploiting or licensing the CIT technology will be significantly impaired. As of the date of this report, due to our
financial situation, we were unable to maintain the retainer with counsel representing us in these matters and they therefore
withdrew as counsel. According, we are not represented by legal counsel at this time and cannot guarantee we will be able to
retain new counsel. This will have a negative impact on our ability to defend the appeal.



On December 8, 2010, Ironridge Global IV,
Ltd. (“Ironridge”) filed a complaint against us in the Superior Court of California, Los Angeles County. Ironridge
claims that we breached a contract with them by allegedly discussing and then entering into transactions to settle certain of our
outstanding liabilities with our creditors during a 30-day exclusivity period, during which Ironridge claims they had the exclusive
right to do so. Ironridge is seeking damages in excess of $30.0 million. We believe that the Ironridge claims are totally without
merit and intend to defend our position vigorously.



On May 16 and May 21, 2012, two former
employees filed a Notice of Claim and Conference with the Labor Commissioner of the State of California against us for unpaid wages
accrued from February 2012 to March 2012 and accrued vacation pay.



Page 14 of 132







If the material weaknesses or other
deficiencies in our internal accounting procedures are not remediated, we will not comply with the rules under the Sarbanes-Oxley
Act related to accounting controls and procedures or our stock price could decline significantly.



Section 404 of the Sarbanes-Oxley Act required
annual management assessments of the effectiveness of our internal controls over financial reporting commencing December 31, 2007.



Our management concluded the consolidated
financial statements included in our Annual Report on Form 10-K for the two-years ended December 31, 2011 and 2010, fairly present
in all material respects our consolidated financial condition, results of operations and cash flows in conformity with accounting
principles generally accepted in the U.S.



Our management evaluated the effectiveness
of our internal control over financial reporting as of December 31, 2011 and 2010 based on the control criteria established in
a report entitled Internal Control — Integrated Framework, issued by the Committee of Sponsoring Organizations of the Treadway
Commission. Based on this evaluation, our management concluded our internal control over financial reporting was not effective
as of December 31, 2011 and 2010. During its evaluation, as of December 31, 2011 our management identified material weaknesses
in our internal control over financial reporting and other deficiencies as described elsewhere in this Report . As a result, our
investors could lose confidence in us, which could result in a decline in our stock price.



We are taking steps to remediate our material
weaknesses. However, if we fail to achieve and maintain the adequacy of our internal controls, we may not be able to ensure that
we can conclude in the future that we have effective internal controls over financial reporting in accordance with Section 404
of the Sarbanes-Oxley Act. Moreover, effective internal controls, particularly those related to revenue recognition, are necessary
for us to produce reliable financial reports and are important to helping prevent financial fraud. If we cannot provide reliable
financial reports or prevent fraud, our business and operating results could be harmed, investors could lose confidence in our
reported financial information, and the trading price of our stock could decline significantly. In addition, we cannot be certain
that additional material weaknesses or other significant deficiencies in our internal controls will not be discovered in the future.



Risks Related to our Products and
Development of our Business

Limited product development activities;
our product development efforts may not result in commercial products.



We are limited in the number of additional
products we can develop at this time. Successful cancer detection and treatment product development is highly uncertain, and very
few research and development projects produce a commercial product. Products like Onko-Sure® appear promising in the early
phases of development may fail to reach the market for a number of reasons, such as:



| | · | the product candidate did not demonstrate
acceptable clinical trial results even though it demonstrated positive preclinical trial results;
| | - | -------------------------------------------------------------------------------------------------------------------------------------------



| | · | the product candidate was not effective
in treating a specified condition or illness;
| | - | -------------------------------------------------------------------------------------



| | · | the product candidate had harmful side
effects on humans;
| | - | ---------------------------------------------------------



| | · | the necessary regulatory bodies did not
approve our product candidate for an intended use;
| | - | ------------------------------------------------------------------------------------------



| | · | the product candidate was not economical
for us to manufacture and commercialize; and
| | - | -------------------------------------------------------------------------------------



| | · | the product candidate is not cost effective
in light of existing therapeutics.
| | - | ------------------------------------------------------------------------------



Of course, there may be other factors that
prevent us from marketing a product including, but not limited to, our limited cash resources. We cannot guarantee we will be able
to produce commercially successful products. Further, clinical trial results are frequently susceptible to varying interpretations
by scientists, medical personnel, regulatory personnel, statisticians and others, which may delay, limit or prevent further clinical
development or regulatory approvals of a product candidate. Also, the length of time that it takes for us to complete clinical
trials and obtain regulatory approval in multiple jurisdictions for a product varies by jurisdiction and by product. We cannot
predict the length of time to complete necessary clinical trials and obtain regulatory approval.



Page 15 of 132







We have limited sales of the Onko-Sure®
test kit and are reliant on our distributors for sales of our products.



Virtually all of our
operating revenues come from the sale of Onko-Sure® to distributors and research users. Historically, we have not
received any substantial orders from any of our customers or distributors of Onko-Sure® test kits. Through December 31,
2011, total sales of Onko-Sure® test kits were $313,559 as compared to $231,662 in total sales of such product in fiscal
2010. Due to the lack of funds, we are unable to continue the sales and marketing of our kits which impacts our efforts to
increase or maintain our distribution network. In addition, the amount of Onko-Sure® test kits purchased by our
distributors can be adversely affected by a number of factors, including market challenges of commercializing a recently
approved biotech product, budget cycles and the amount of resources available for marketing programs, demand creation
activities, and outreach to appropriate healthcare professionals and targeted markets. At this time, until we receive
additional financing, it is likely that our sales efforts will cease.



Our current products cannot be sold
in certain countries if we do not obtain and maintain regulatory approval.



We manufacture, distribute and market our
products for their approved indications. These activities are subject to extensive regulation by numerous state and federal governmental
authorities in the U.S., such as the USFDA and the Centers for Medicare and Medicaid Services (formerly Health Care Financing Administration)
and certain foreign countries, including some in the European Union;. Currently, we (or our distributors) are required in the U.S.
and in foreign countries to obtain approval from those countries’ regulatory authorities before we can market and sell our
products in those countries. Obtaining regulatory approval is costly and may take many years, and after it is obtained, it remains
costly to maintain. The USFDA and foreign regulatory agencies have substantial discretion to terminate any clinical trials, require
additional testing, delay or withhold registration and marketing approval and mandate product withdrawals. In addition, later discovery
of unknown problems with our products or manufacturing processes could result in restrictions on such products and manufacturing
processes, including potential withdrawal of the products from the market. If regulatory authorities determine that we have violated
regulations or if they restrict, suspend or revoke our prior approvals, they could prohibit us from manufacturing or selling our
products until we comply, or indefinitely.



We have do not have any
product liability insurance.



We currently produce products
for clinical studies and for investigational purposes. We are producing our products in commercial sale quantities, which
will increase as we receive various regulatory approvals in the future. There can be no assurance, however, that users will
not claim that effects other than those intended may result from our products, including, but not limited to claims alleged
to be related to incorrect diagnoses leading to improper or lack of treatment in reliance on test results. In the event
that liability claims arise out of allegations of defects in the design or manufacture of our products, one or more claims
for damages may require the expenditure of funds in defense of such claims or one or more substantial awards of damages
against us, and may have a material adverse effect on us by reason of our inability to defend against or pay such claims. Our
severe working capital shortages has prevented us from being able to pay the premiums associated with our products liability
insurance. As a result, products liability insurance was cancelled June 1, 2012.



If our intellectual property positions
are challenged, invalidated or circumvented, or if we fail to prevail in future intellectual property litigation, our business
could be adversely affected.



The patent positions of pharmaceutical
and biotechnology companies can be highly uncertain and often involve complex legal, scientific and factual questions. To date,
there has emerged no consistent policy regarding breadth of claims allowed in such companies’ patents. Third parties may
challenge, invalidate or circumvent our patents and patent applications relating to our products, product candidates and technologies.
In addition, our patent positions might not protect us against competitors with similar products or technologies because competing
products or technologies may not infringe on our patents.



We face substantial competition,
and others may discover, develop, acquire or commercialize products before or more successfully than we do.



We operate in a highly competitive environment.
Our products compete with other products or treatments for diseases for which our products may be indicated. Additionally, some
of our competitors market products or are actively engaged in research and development in areas where we are developing product
candidates. Large pharmaceutical corporations have greater clinical, research, regulatory and marketing resources than we do. In
addition, some of our competitors may have technical or competitive advantages over us for the development of technologies and
processes. These resources may make it difficult for us to compete with them to successfully discover, develop and market new products.



Page 16 of 132







We have a limited supply of one of
the key components of the Onko-Sure®



Although the Company has obtained approval
from the USFDA to market the then current formulation of the Onko-Sure® test kit, it has been determined that one of the key
components of the Onko-Sure® test kit, the anti-fibrinogen-HRP is limited in supply and additional quantities cannot be purchased.
Currently, we have two lots remaining which are estimated to produce approximately 21,000 kits. In order to utilize in kits, we
will need to purify and quality control the lots. We currently have enough purified and quality checked anti-fibrinogen-HRP to
manufacture 200 kits. We will need to purify and quality check additional lots to fill expected orders. We have been investigating
alternatives and engaging in research and development to produce this component in house so that we can be in a position to have
an unlimited supply of Onko-Sure® in the future. Due to the lack of funding, we suspended research and development including
the initial validation studies which were scheduled to be completed by the end of the third quarter of fiscal 2012. Without such
replacement, we will not be able to produce any additional kits once our current supply is used.



We are subject to risks associated
with our foreign distributors.



Our business strategy includes the continued
dependence on foreign distributors for our Onko-Sure® test kits. To date, we have not been successful in generating a significant
increase in sales for Onko-Sure® test kits through foreign distribution channels in existing markets or in developing foreign
distribution channels in new markets. We are also subject to the risks associated with our foreign distributor’s operations,
including: (i) fluctuations in currency exchange rates; (ii) compliance with local laws and other regulatory requirements; (iii)
restrictions on the repatriation of funds; (iv) inflationary conditions; (v) political and economic instability; (vi) war or other
hostilities; (vii) overlap of tax structures; and (viii) expropriation or nationalization of assets. The inability to manage these
and other risks effectively could adversely affect our business.



Our Business depends on retaining
and maintaining good relations with our employees.



We are dependent upon the ability and experience
of our executive officers, managers, employees and other personnel and there can be no assurance we will be able to retain all
of such employees. As of April 17, 2013 all employees except for two were laid off.



Temporary or extended lay-offs due to financial
constraints may result in vacancies or the need to hire less skilled or efficient employees. The loss of these persons or our inability
to attract and retain highly skilled employees could have an adverse effect on our business and future operations. As of the date
of this report, two former employees have filed a Notice of Claim and Conference with the Labor Commissioner, State of California
for payment of accrued wages.





Due to our current and recent financial condition, we
have been unable to pay the premiums on our Officer and Director liability insurance.



Our severe working capital shortage has prevented us from being
able to pay the premiums associated with our Director and Officer Insurance.  As a direct result of the loss of such insurance,
two of our directors decided to resign.  Although our remaining officers and directors are currently continuing in their roles,
there can be no guarantee that they too will not have to resign if we are unable to reacquire such insurance.  Additionally,
if we are unable to reacquire and maintain such insurance, it will probably be more difficult for us to attract and retain qualified
individuals to serve on our board of directors or as executive officers.





Risks Relating to Our Securities



There have been material decreases
in the market prices of our common stock.



As of June 15, 2012 the closing bid price
of our common stock was $0.0001 per share. From January 2011 through June 15, 2012, our common stock has had a trading range with
a low price of $0.0001 per share and a high price of $41.75 per share. In contrast, during the two years ending December 31, 2011
and 2010, our common stock has had a trading range with a low price of $0.055 per share and a high price of $41.75 per share. There
can be no assurance that the market prices of our common stock will not materially decrease again, especially as holders of our
convertible notes and convertible preferred stock and warrants sell the underlying shares issuable upon conversion or exercise
of such securities, whether in accordance with the sale limits agreed upon or otherwise. From January 2011 through June 15, 2012,
our common stock traded an average of approximately 5,640,365 shares per day.



Page 17 of 132









The interests of our current stockholders
in the equity of our company are subject to substantial dilution.



We have a significant number of warrants
and options outstanding and a large amount of convertible notes and convertible preferred stock which “over hang” the
market for our common stock. At June 15, 2012, we had:



| | · | Approximately 313,000,000 of outstanding warrants at a weighted average exercise price of $0.07
per share (subject to adjustment), including approximately 307,754,000 Series A warrants at a weighted average exercise price of
$0.055825 per share (subject to adjustment);
| | - | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
| |   |                                                                                                                                                                                                                                                                              

| | · | Approximately 12.9 million options outstanding and vested within sixty days at a weighted average
exercise price of $0.38 per share;
| | - | ------------------------------------------------------------------------------------------------------------------------------------
| |   |                                                                                                                                     

| | · | Approximately $13.1 million in convertible notes;
| | - | -------------------------------------------------
| |   |                                                  

| | · | Approximately $3.4 million in outstanding Series B Convertible Preferred Stock;
| | - | -------------------------------------------------------------------------------
| |   |                                                                                

| | · | Approximately $500,000 in outstanding Series C Convertible Preferred Stock.
| | - | ---------------------------------------------------------------------------



Due to the current price of our stock and
the conversion price set forth in each instrument (See Note 8), we would be unable to issue all shares that are potentially issuable
due to the limitation of the number of authorized shares of common stock of 5 billion. In the event a portion of warrants, options,
convertible notes and preferred stock is exercised or converted, there would be a substantial dilution in the interest of other
stockholders as a result of the additional common stock that would be issued.



Our stock price and ability to finance may be adversely
affected by our outstanding convertible securities and warrants.



Sales of the shares of our common stock
issuable upon exercise of the warrants and upon conversion of our convertible securities, would likely have a depressive effect
on the market price of our common stock. Further, the existence of, and/or potential exercise or conversion of all or a portion
of these securities, create a negative and potentially depressive effect on our stock price because investors recognize that they
“over hang” the market at this time. As a result, the terms on which we may obtain additional financing during the
period any of these warrants or convertible securities remain outstanding may be adversely affected by the existence of such warrants
and convertible securities.



Insiders have substantial control
over us, and they could delay or prevent a change in our corporate control even if our other stockholders wanted it to occur.



Our executive officers, directors, and
principal stockholders beneficially own, in the aggregate, approximately less than 1% of our outstanding common stock at June
15, 2012. These stockholders are able to control all matters requiring stockholder approval, including the election of directors
and approval of significant corporate transactions. This could delay or prevent an outside party from acquiring or merging with
us even if our other stockholders wanted it to occur.





On a fully diluted basis, the percentage of our executive officers
and directors will be approximately 0.00%. The percentage of beneficial ownership is based on 5 billion shares outstanding as of
June 15, 2012. This is based on 1,347,936,151 shares outstanding as of June 15, 2012 and assuming (i) the conversion of all outstanding
notes, (ii) conversion of all outstanding preferred stock and accrued dividends, (iii) exercise of warrants and options, up to
the maximum authorized shares of 5 billion common shares.



Page 18 of 132







Our common stock is a “penny stock” and may
be difficult to sell.



The SEC has adopted regulations which generally
define a “penny stock” to be an equity security that has a market price of less than $5.00 per share or an exercise
price of less than $5.00 per share, subject to specific exemptions. The market price of our common stock is less than $5.00 per
share and, therefore, it may be designated as a “penny stock” according to SEC rules. This designation requires any
broker or dealer selling these securities to disclose certain information concerning the transaction, obtain a written agreement
from the purchaser and determine that the purchaser is reasonably suitable to purchase the securities. These rules may restrict
the ability of brokers or dealers to sell our common stock and may affect the ability of investors to sell their shares.



The market for penny stocks has experienced
numerous frauds and abuses which could adversely impact investors in our stock.



Penny stocks are frequent targets of fraud
or market manipulation. Patterns of fraud and abuse include:



| | · | Control of the market for the security
by one or a few broker-dealers that are often related to the promoter or issuer;
| | - | -----------------------------------------------------------------------------------------------------------------------



| | · | Manipulation of prices through prearranged
matching of purchases and sales and false and misleading press releases;
| | - | -------------------------------------------------------------------------------------------------------------------



| | · | “Boiler room” practices involving
high pressure sales tactics and unrealistic price projections by inexperienced sales persons;
| | - | -------------------------------------------------------------------------------------------------------------------------------



| | · | Excessive and undisclosed bid-ask differentials
and markups by selling broker-dealers; and
| | - | ------------------------------------------------------------------------------------------



| | · | Wholesale dumping of the same securities
by promoters and broker-dealers after prices have been manipulated to a desired level, along with the inevitable collapse of those
prices with consequent investor losses.
| | - | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Our management is aware of the abuses that
have occurred historically in the penny stock market.



Our stock price is volatile, which
could adversely affect your investment.



Our stock price, like that of other international
bio-pharma and/or cancer diagnostic companies, is highly volatile.



Our stock price may
be affected by such factors as:



| | · | clinical trial results;
| | - | -----------------------



| | · | product development announcements by us or our competitors;
| | - | -----------------------------------------------------------



| | · | regulatory matters;
| | - | -------------------



| | · | announcements in the scientific and research community;
| | - | -------------------------------------------------------



| | · | intellectual property and legal matters; and
| | - | --------------------------------------------



| | · | broader industry and market trends unrelated to our performance.
| | - | ----------------------------------------------------------------





In addition, if our revenues or operating
results in any period fail to meet the investment community’s expectations, there could be an immediate adverse impact on
our stock price.



Our publicly filed reports are subject
to review by the SEC, and any significant changes or amendments required as a result of any such review may result in material
liability to us and may have a material adverse impact on the trading price of the Company’s common stock.



The reports of publicly traded companies
are subject to review by the SEC from time to time for the purpose of assisting companies in complying with applicable disclosure
requirements, and the SEC is required to undertake a comprehensive review of a company’s reports at least once every three
years under the Sarbanes-Oxley Act of 2002. SEC reviews may be initiated at any time. We could be required to modify, amend or
reformulate information contained in prior filings as a result of an SEC review. Any modification, amendment or reformulation of
information contained in such reports could be significant and result in material liability to us and have a material adverse impact
on the trading price of the Company’s common stock.



Page 19 of 132







The delisting of our common stock from the OTCQX to OTCQB
constitutes an event of default under certain of our outstanding notes which may result in acceleration of the payment of the entire
outstanding balance of their notes



We received a notice from the Pink OTC
Markets Inc., dated August 23, 2011 notifying us that we were out of compliance with OTCQX Rules for U.S. Companies section 3.2.b,
which states, in essence, that our common stock must have a minimum closing bid price of $0.10 per share at least once in every
thirty consecutive trading days. If our common stock does not meet that requirement, we have 180 days to regain compliance therewith
by maintaining a $0.10 closing bid price for ten consecutive trading days during such grace period. The grace period ended on February
20, 2012 and because our common stock did not meet the closing bid price requirement, our common stock will move down from the
OTCQX tier of the OTC Markets to the OTCQB tier of the OTC Markets, as of February 22, 2012. The main difference between the OTCQB
and OTCQX is that stocks listed on the OTCQX undergo additional quality review and have different listing standards than those
on the OTCQB, although both are tiers of the OTC Markets. Our trading symbol shall remain the same.



The delisting of our common stock from
the OTCQX constitutes an event of default under certain of our outstanding notes, including the “2011 Noteholders”
(as that term is defined in our Form 8-K dated November 29, 2011). As of June 15, 2012, such notes have a total outstanding balance
of approximately $13.0 million. Under the default provisions of such notes, the holders maintain the right to accelerate the payment
of the entire outstanding balance of their notes. In addition, the 2011 Noteholders have the right to demand redemption of all
of their outstanding Series B Preferred Stock. As of the date of this filing, an aggregate of 338,078 shares of Series B Preferred
Stock and 50,000 shares of Series C Preferred Stock is outstanding.



As disclosed in Form 8-K filed on February
23, 2012, our common stock was delisted from the OTCQX tier of the OTC Markets and moved to the OTCQB tier of the OTC Markets.
We also disclosed our inability to pay our accounts payable and other obligations in the ordinary course of business. As further
disclosed, each such event constitutes an event of default under certain of our outstanding notes, including the “2011 Noteholders”
(as that term is defined in our Form 8-K dated November 29, 2011); it also constitutes a triggering event under the terms of our
Series B and Series C preferred stock, which can result in redemption of such stock.



Between March 26, 2012 and April 3, 2012,
we received an Event of Default Redemption Notice and a Notice of Redemption from four note holders. Pursuant to the Event of Default
Redemption Notice, each note holder elected to redeem their respective note in full, thereby requiring immediate payment of the
entire outstanding balance of their note. Failure to pay the balance by April 2, 2012, will activate the late charges of 24% per
annum until the redemption price is paid in full. Pursuant to the Notice of Redemption, each note holder elected to redeem all
of their respective shares of Series B Preferred Stock and Series C Preferred Stock at the current redemption price, which must
be paid by April 2, 2012. Failure to pay by April 2, 2012 triggers interest payments at the rate of 2% per month for each unredeemed
share until the redemption price is paid in full



These same three note holders also asserted
claims against the Company's officers and directors for breaches of fiduciary duties of care, loyalty, good faith and disclosure,
self-dealing and waste and spoliation of corporate assets. Pursuant thereto, the note holders asserted damages in amounts equal
to at least $4.25 million or $2.25 million, respectively.



Due to the absence of any working capital,
we are unable to pay the redemption prices at this time. However, as previously stated, pursuant to the May Agreement, these note
holders agreed to certain forbearances regarding these, and other defaults pending we satisfy specific conditions by the contractual
deadlines set forth in such agreement. If we do not satisfy these conditions, the note holders may re-establish their previous
claims and defaults, which may cause us to cease operations, declare bankruptcy or take other actions that would cause us to terminate
our business



Item 1B. Unresolved Staff Comments



None.



Page 20 of 132







Item 2.Properties



Our office in the U.S. consists of a research
laboratory and manufacturing facility which occupies 4,395 square feet and is located at 2492 Walnut Avenue, Suite 100, Tustin,
California. We leased this facility at a monthly rate of $6,900 per month, including property taxes, insurance and maintenance
through December 1, 2010. The lease was extended through August 31, 2011. After August 31, 2011, we leased the facility based on
month-to-month lease agreement



Item 3.Legal Proceedings



On February 22, 2002, AcuVector
Group, Inc. (“AcuVector”) filed a statement of claim in the Court of Queen’s Bench of Alberta, Judicial
District of Edmonton relating to the Company’s CIT technology acquired from Dr. Chang in August 2001. The claim alleged
damages of $CDN 20 million and sought injunctive relief against Dr. Chang for, among other things, breach of contract and
breach of fiduciary duty, and against the Company for interference with the alleged relationship between Dr. Chang and
AcuVector. The Company filed a motion to dismiss all claims and the motion was granted in favor of the Company dismissing the
action on September 30, 2011. The Company also defended a companion case filed in the same court the Governors of the
University of Alberta filed against the Company and Dr. Chang in August 2003. The Court approved an order to dismiss the
cases. However, opposing counsel, who approved the form of order, filed an appeal on December 23, 2011. Although we believe
both actions are without merit and that the dismissal order should be upheld, it is possible the order will be overturned and
then if either AcuVector or the University is successful in their claims, we may be liable for substantial damages, our
rights to the technology will be adversely affected and our future prospects for exploiting or licensing the CIT technology
will be significantly impaired. As of the date of this report, we are not represented by counsel in these matters. Due to our
financial situation, we were unable to maintain the retainer with counsel representing us in these matters and therefore they
withdrew as counsel. We will try to defend the appeal, but without legal representation, it may prove difficult to do so.



On June 11, 2010, Hudson Bay Fund, LP.
(“Hudson Bay”) filed a statement of claim in the Court of Cook County, County Department, Law Division, State of Illinois
relating to their participation in the Second Closing of the Note Financings. The claim alleges that a Trigger Event occurred,
because the respective registration statement was not declared effective on or before June 1, 2010. As a result of the Trigger
Event, the balance was immediately increased to 125% of the outstanding balance; we noted this Trigger Event and recorded same
in our accompanied financial statements. Moreover, the claim alleged that an additional Trigger Event occurred because we did not
cure the first Trigger Event within five trading days. As a result of this alleged Second Trigger Event, Hudson Bay alleges that
the outstanding balance of the Note should be immediately increased by an additional 125%. On January 21, 2011 Hudson agreed to
exchange the notes for an aggregate of 1,140,357 shares of the Company's common stock pursuant to Section 3(a)(9) of the Securities
Act of 1933, as amended. As a result of the exchange, such notes are no longer outstanding and the Company and Hudson accordingly
agreed to execute and file an order dismissing the June 11, 2010 compliant, with prejudice. The dismissal order was filed on January
21, 2011.



On March 11, 2011, a putative shareholder
class action was filed against the Company and two of its officers alleging that they violated federal securities laws by misrepresenting
the relationship between the Company and third parties involved in the Company’s clinical studies of the Onko-Sure® test
kit. The trial court granted in part, and denied in part, the defendants’ motions to dismiss the complaint, and the case
is now proceeding to discovery. The Company and defendant officers vehemently deny the allegations in the complaint and are vigorously
defending the action. Due to the uncertain nature of litigation and the early stage of the lawsuit, we cannot calculate the potential
damages – nor does the complaint seek any specific monetary amount of damages.



On December 8, 2011, Ironridge Global IV,
Ltd. (“Ironridge”) filed a complaint against us in the Superior Court of California, Los Angeles County. Ironridge
claims that we breached a contract with them by allegedly discussing and then entering into transactions to settle certain of our
outstanding liabilities with holders of our convertible securities during a 30-day exclusivity period, during which Ironridge claims
it had the exclusive right to do so. Ironridge is seeking damages in excess of $30.0 million. We believe that the Ironridge claims
are totally without merit, that Ironridge met with substantially all of the holders of such convertible notes and related securities
and, in fact, did business with certain of such creditors who elected to deal with Ironridge. As such, we believe that we performed
all of our obligations under such contract and intend to defend our position vigorously.



On December 10, 2010, Alpha Capital Anstalt
(“Alpha Capital”) and Whalehaven Capital Fund Ltd. (“Whalehaven Capital and with Alpha Capital, the “Plaintiffs”)
filed a complaint against us regarding the number of warrants they received in the Registered Direct Offering (“RDO”)
that we completed in November 2009 and the shareholder vote obtained at our December 3, 2010 annual shareholder meeting. The Plaintiffs
alleged that the effective price of the notes we issued pursuant to the private financing we completed in March and April 2010,
and of the shares we later issued to two such note holders in settlement of a lawsuit with same, is lower than what we claim it
to be and that such alleged effective price requires a greater reset to the exercise price of the warrants they received in the
RDO. Additionally, they allege that we solicited votes against one of the proposals related to the RDO that was proposed at the
December 3, 2010 annual shareholder meeting. The Plaintiffs sought relief from the court involving additional shares issuable pursuant
to the exercise of the warrants they received in the RDO and cash damages.



Page 21 of 132







As reported in the Company’s Form
8-K dated May 17, 2011, on May 10, 2011, we entered into a Settlement Agreement with the Plaintiffs pursuant to which we agreed
to issue that number of shares of our common stock equal in value to $10,912,055 at the time of issuance (the “Settlement
Amount”). On May 24, 2011 we received court approval to issue such shares pursuant to the provisions of Section 3(a)(10)
of the Securities Act of 1933, as amended. Under the terms of the court approved settlement, the parties filed a Stipulation of
Discontinuance of the lawsuit with the relevant court. As part of the Settlement Agreement, Alpha Capital and Whalehaven Capital
retained all of the warrants the Plaintiffs received in the RDO and in the private financing we closed in March and April 2010.
We are obligated to issue to Alpha Capital and Whalehaven Capital as many shares of our common stock as possible to reach the Settlement
Amount that the NYSE Amex had previously approved for issuance to the Plaintiffs. On May 25, 2011, we issued an aggregate of 20,000
shares of our common stock in accordance with the Settlement Agreement; 11,320 shares to Alpha Capital and 8,680 shares to Whalehaven.
Throughout the term of the note, if we no longer need NYSE Amex or shareholder approval, all shares issuable pursuant to the Settlement
Agreement shall be issued. On June 23, 2011, the Company was no longer listed on NYSE Amex; and therefore, on June 29, 2011, we
issued an aggregate of 820,000 of our common shares; 464,120 shares to Alpha Capital and 355,880 shares to Whalehaven Capital.
In addition, and in order to account for the time it may take to receive shareholder approval to authorize sufficient additional
shares that are issuable to them, the Plaintiffs agreed to accept a promissory note for the monetary value of that number of additional
shares that would be required to be issued to achieve the Settlement Amount upon Court Approval based on a pre-determined formula
set forth in the Notes. The notes bear 8% interest and mature four months after issuance. We maintain the right to pay the note
back in cash or shares of common stock based upon a pre-determined formula set forth in the notes. Upon the occurrence of an event
of default, the note will become immediately due and payable. Under the Settlement Agreement, Plaintiffs are entitled to entry
of judgment in the amount of principal outstanding, if any, on the maturity date. The Settlement Agreement also contemplates the
issuance of additional shares to Plaintiffs or the return of shares to us based upon variances in the market price of our common
stock between the date we receive Court Approval and sixty days following the maturity date of the notes.



On June 23, 2011, we advised Plaintiffs
that due to the fact that each of the convertible notes held by Whalehaven and Alpha Capital are, by their stated terms, immediately
convertible at the option of the holders into more than ten percent (10%) of the issued and outstanding shares of common stock
of the Company, each of the Plaintiffs is an affiliate of the Company as defined in Rule 144(a) of the Securities Act. As such,
any additional Settlement Shares issued to the Plaintiffs under the Settlement Agreement would have to comply with the applicable
provisions of the Securities Act and specifically Rule 144 promulgated thereunder with regard to any resale. Accordingly we advised
plaintiffs that the additional 20.5 million shares issued to them pursuant to Section 3(a)(10) may only be resold by Plaintiffs
in compliance with Rule 144. These shares are not “restricted securities” within the meaning of Rule 144(a), they are
not subject to the holding period limitations of Rule 144(d). However, they are subject to the other relevant provisions of Rule
144, including (i) the limitation of the amount of securities that may be sold by an affiliate pursuant to Rule 144(e)(1) and the
manner of sale pursuant to Rule 144(f).



On July 19, 2011 Plaintiffs wrote a letter
to the Court disputing our position that they are affiliates and seeking judgment in default of the Settlement Agreement. We strongly
believe that a default has not occurred; we maintain that we are in compliance with the terms of the Settlement Agreement and we
are vigorously defending our position.



On August 19,
2011, the Company entered into a Memorandum of Understanding with Alpha Capital and Whalehaven. On August 25, 2011, a Final Settlement
Agreement was reached to settle the July 19, 2011 Letter. On August 26, 2011, the Final Settlement Agreement was recorded and approved
in the Court. We have since modified certain terms of the Final Settlement to impose a trading limitation on the Plaintiffs sale
of our common stock and a lower ownership cap.The Plaintiffs also waived the installment payments owed to them under their
notes, although we remain liable for any principal and interest outstanding on the maturity date.



As reported in the Company’s Form
8-K dated May 11, 2011, we were in default to each of Iroquois Master Fund Ltd., Cranshire Capital, L.P., Freestone Advantage Partners,
L.P., Bristol Investment Fund, Ltd. and Kingsbrook Opportunities Master Fund LP, (collectively, the “2011 Note holders”),
the holders of our convertible notes due December 1, 2011 (the “2011 Notes”) in the original principal amount of $8,437,500.
As a result of such defaults, our total liabilities (including accrued interest, penalties and default redemption payments) to
the 2011 Note holders aggregated $22,301,761. We entered into an exchange agreement on June 29, 2011, with each of the 2011 Note
holders (the “Exchange Agreement”) in order to settle our obligations to each of the 2011 Note holders. This transaction
was legally consummated and recorded for financial reporting purposes on July 1, 2011.



Page 22 of 132







Following a fairness hearing held on September
30, 2011, in the Supreme Court of the State of New York (the “Court”), the Court entered an order approving (i) the
fairness of the terms and conditions of the proposed exchange and the transactions contemplated by the Exchange Agreement, (ii)
the terms and conditions of the proposed exchange and the transactions contemplated by the Exchange Agreement and (iii) the issuance
of the Notes, the shares of Preferred Stock and the Warrants pursuant to the exemption from registration under Section 3(a)(10)
of the Securities Act of 1933, as amended (the “3(a)(10) Order”).



As reported in the Company’s Form
8-K dated November 28, 2011, on November 28, 2011, we entered into separate exchange agreements with each of the 2011 Noteholders
(the “November Exchange Agreements”), the form of which is attached hereto as Exhibit 10.3, pursuant to which each
2011 Noteholder agreed to exchange all of its respective Initial Settlement Securities for the securities described below. Due
to the occurrence of various events of defaults under the 4% Notes and triggering events under the Preferred Stock, the Company
determined it was in its best interest to enter into the November Exchange Agreement. The following securities of the Company will
be issued in exchange for the Initial Settlement Securities:



| | (a) | 402,411 shares of the Company’s preferred stock designated as “Series B Convertible
Preferred Stock” (the “Series B Preferred Stock”), which Series B Preferred Stock shall, in accordance with its
terms, (i) rank senior to all of the Company’s other equity securities, (ii) be initially convertible into approximately
72.1 million shares of the Company’s common stock, $0.001 par value per share, (iii) have a par value of $0.001 per share,
(iv) have a stated value of $10.00 per share, (v) accrue dividends at the rate of 4% per annum which shall be payable in shares
of common stock, in arrears upon each conversion of such stock and (vi) contain such other rights, preferences and limitations
as are set forth in the Certificate of Designations of Series B Convertible Preferred Stock, which is attached as Exhibit 10.4
attached hereto (the “Series B Certificate of Designations”);
| | --- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (b) | convertible notes, in the form attached hereto as Exhibit 10.5, in the original principal amount
of $4,950,000, which notes shall be initially convertible into approximately 88.7 million shares of Common Stock, in accordance
with the terms thereof (the “November Notes”) and mature on November 28, 2012;
| | --- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (c) | warrants to acquire up to approximately 313.5 million shares of Common Stock, in the form attached
hereto as Exhibit 10.6 (the “Series A Warrants”), in accordance with the terms of the Series A Warrants; and
| | --- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (d) | warrants, in the form attached hereto as Exhibit 10.7 (the “Series B Warrants,” together
with the Series A Warrants, the “November Warrants”), to acquire 50,000 shares of the Company’s preferred stock
designated as Series C Convertible Preferred Stock (the “Series C Preferred Stock,” together with the Series B Preferred
Stock, the “November Preferred Stock”), which Series C Preferred Stock shall, in accordance with its terms, (i) rank
junior to the Series B Preferred Stock and senior to all of the Company’s other equity securities, (ii) accrue dividends
at the rate of 4% per annum, which shall be payable in shares of common stock, in arrears upon each conversion of such stock, (iii)
are convertible into shares of Common Stock, (iv) have a par value of $0.001 per share, (v) have a stated value of $10.00 per share
and (vi) contain such other rights, preferences and limitations as are set forth in the Certificate of Designations of Series C
Convertible Preferred Stock attached hereto as Exhibit 10.8 (the “Series C Certificate of Designations”).
| | --- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Page 23 of 132







Each of the November Notes, shares of Series
B Preferred Stock and shares of Series C Preferred Stock are initially convertible into shares of our common stock at a conversion
price equal to the lowest of (i) $0.055825, (the “Fixed Conversion Price”), (ii) the price which is equal to the product
of (1) 80% multiplied by (2) the quotient of (A) the sum of each of the three (3) lowest daily weighted average prices of our common
stock during the twenty (20) consecutive trading day period immediately preceding the date of the conversion or other applicable
date of determination (as applicable) divided by (B) three (3) (as adjusted for any stock split, stock dividend, stock combination
or other similar transaction during any such twenty (20) trading day period) and (iii) the price which is equal to 80% of the closing
bid price of our common stock on the trading day immediately preceding the date of conversion or other applicable date of determination
(as applicable) (as adjusted for any stock split, stock dividend, stock combination or other similar transaction occurring on the
applicable date of conversion or other applicable date of determination (as applicable)). However, if we make certain dilutive
issuances (with limited exceptions), the conversion price of the November Notes and the shares of November Preferred Stock will
be lowered to the per share price for the dilutive issuances. The Series A Warrants are initially exercisable for shares of our
common stock at an exercise price of $0.055825 per share; provided however, if we make certain dilutive issuances (with limited
exceptions), the exercise price of the Series A Warrants will be lowered to the per share price for the dilutive issuances. The
Series A Warrants may also be exercised on a “cashless basis” under various circumstances. The Series B Warrants are
exercisable for shares of our Series C Preferred Stock at an exercise price of $10.00 per share. The conversion prices of the Notes,
the shares of the November Preferred Stock and the exercise price of the Series A Warrants are also subject to adjustment in the
case of stock splits, stock dividends, combinations of shares and similar recapitalization transactions; the exercise price of
the Series B Warrants are only subject to adjustment in the case of stock splits, stock dividends or combinations of the Series
C Preferred Shares. The convertibility of the November Notes, November Preferred Stock and the exercisability of the Series A Warrants
may be limited if, upon conversion or exercise thereof, the holder thereof or any of its affiliates would beneficially own more
than 1% of our common stock.



Pursuant to the terms of the Series B Warrants,
the Company has the right upon satisfaction of certain conditions (the filing by the Company of this Current Report on Form 8-K
with the SEC and the filing by the Company of the Series C Certificate of Designations with the Delaware Secretary of State) to
require each of the holders of the Series B Warrants to exercise, on no less than one (1) trading day’s notice, all of their
respective Series B Warrant for shares of Series C Preferred Stock. If the Company requires one holder of a Series B Warrant to
so exercise its Series B Warrant, the Company is required to take the same action under all of the other Series B Warrants. If
any shares of Series C Preferred Stock are issued upon exercise of any Series B Warrants, the Company will use all the proceeds
therefrom solely to (a) pay accrued and unpaid legal fees to our legal counsel (not to exceed $65,000 in the aggregate) and (b)
provide ongoing working capital for the Company for a period of not less than ninety (90) days following the first date of issuance
of any shares of Series C Preferred Stock.



The November Notes accrue interest at the
rate of 4% per annum and shall be paid in arrears, in shares of our common stock upon each conversion of the November Note. Upon
the occurrence of an event of default and until it is cured, the November Notes shall accrue interest at the rate of 18%. If an
event of default occurs or change in control transaction occurs we must redeem in cash any Notes submitted to us for redemption
upon the terms set forth in the Notes.



Although the November Notes rank senior
to all of the Company’s outstanding and future debt, with a few exceptions, they rank pari passu with the notes held by the
Plaintiffs. However, neither of the notes issued to the Plaintiffs may be amended, waived, extended or otherwise modified in any
manner or respect without the prior written consent of the holders of the November Notes.



Upon the occurrence of a Triggering Event
or Fundamental Transaction, as such terms are defined in the Series B Certificate of Designations and the Series C Certificate
of Designations, each holder of shares of the November Preferred Stock has a right to force us to redeem any or all of their shares
November Preferred Stock then held by such holder. The transactions contemplated by the November Exchange Agreements were consummated
on November 28, 2011.



On May 15, 2012, we completed an Agreement
with the 2011 Noteholders, severally and not jointly, for the exercise of an aggregate of $150,000 worth of our Series A Common
Stock Purchase Warrants at an exercise price of $0.02619 per share. The proceeds received from such Warrant exercise, shall be
used solely and exclusively to enable us to keep our Registration Statement on Form S-1 filed under the Securities Act of 1933,
as amended, which the Securities and Exchange Commission declared effective on February 14, 2012, current and maintain compliance
with our reporting requirements under the Securities Exchange Act of 1934, as amended.



As
a condition to the exercise of the Warrants, we agreed that following the date of the Agreement and through and including 5:00
p.m. (EDT) on August 31, 2012, we will not file in any U.S. Bankruptcy Court a voluntary petition for reorganization under Chapter
11 of Title 11 of the United States Code or seek to liquidate under Chapter 7 of such Code. Additionally, each of the 2011 Noteholders,
severally and not jointly, agreed to forebear from exercising any of their rights and remedies, whether at law or in equity, against
us and our current and former directors and officers for a period that shall not exceed the earlier to occur of (i) August 31,
2012, or (ii) a breach by us of any of our other covenants and agreements contained in the prior agreements with the 2011 Noteholders
or in the current Agreement, including, without limitation, our commitment to file with the SEC our 2011 Form 10-K by June 30,
2012 and our March 31, 2012 Form 10-Q by July 15, 2012. The 2011 Noteholders further agreed that in the absence of a further breach
of the terms of the Agreement or any of the other agreements between us and the 2011 Noteholders, that each of the previously issued
default notices shall be deemed to be withdrawn ab initio upon execution of the Agreement.



Page 24 of 132







Additionally, as part of the Agreement
and in order to provide for payment of past due legal fees, we agreed to issue to our legal counsel, Hunter Taubman Weiss LLP,
a $300,000 unsecured convertible 4% Company note payable on April 30, 2015, which shall (i) accrue interest at the annual rate
of 4% per annum, (ii) be convertible into our Common Stock at a fixed conversion price of $0.01 per share, (iii) be subject to
prepayment at the option of the Company, (iv) contain full ratchet and other customary anti-dilution protection, and (v) not be
subject to any mandatory installment or other mandatory prepayment provisions prior to the April 30, 2015 maturity date.



On May 16 and May 21, 2012, two former
employees filed a Notice of Claim and Conference with the Labor Commissioner; State of California against us for unpaid wages accrued
from February 2012 to March 2012 and accrued vacation pay. The special committee of the Board of Directors is reviewing a plan
out forth by management to resolve outstanding salaries and accrued vacation.



Other than the above mentioned litigation
matters, neither we nor any of our direct or indirect subsidiaries is a party to, nor is any of our property the subject of, any
legal proceedings other than ordinary routine litigation incidental to their respective businesses. There are no proceedings pending
in which any of our officers, directors or 5% shareholders are adverse to us or any of our subsidiaries or in which they are taking
a position or have a material interest that is adverse to us or any of our subsidiaries.



From time to time, we may be involved in
litigation relating to claims arising out of our operations in the normal course of business.



Item 4.Mine Safety Disclosure



Not applicable.



Page 25 of 132









PART II



Item 5.Market for Registrant’s Common Equity, Related
Stockholder Matters and Issuer Purchases of Equity Securities



Our common stock is listed on the OTC Market, OTCQB under the
symbol “RXPC.”



Our stock price, like that of some other
cancer diagnostic and pharmaceutical companies, is highly volatile. Our stock price may be affected by a number of factors, and
especially significant sales of shares by 2011 Noteholders and holders of our RDO Notes.



In addition, if our revenues or earnings
in any period fail to meet the investment community’s expectations, there could be an immediate adverse impact on our stock
price.



Market Information — Our common
shares are currently listed on the OTC Market under the symbol “RXPC”. On June 15, 2012, the closing price of our common
shares on OTC Market was $0.0002.



Set forth in the following table are the
high and low closing prices for the years ended December 31, 2010 and 2011 and for the three months ended March 31, 2012 for our
common stock.



|              |  | High |       |  | Low |  
|------------- |  | ---- | ----- |  | --- | -
|Quarter Ended |  |      |       |  |     |  
|31-Mar-10     |  | $    | 9.50  |  |     | $
|30-Jun-10     |  | $    | 54.75 |  |     | $
|30-Sep-10     |  | $    | 25.75 |  |     | $
|31-Dec-10     |  | $    | 25.50 |  |     | $
|Quarter Ended |  |      |       |  |     |  
|31-Mar-11     |  | $    | 41.75 |  |     | $
|30-Jun-11     |  | $    | 12.81 |  |     | $
|30-Sep-11     |  | $    | 3.88  |  |     | $
|31-Dec-11     |  | $    | 0.30  |  |     | $
|31-Mar-12     |  | $    | 0.08  |  |     | $



Record Holders. As of June 15, 2012,
there were approximately 1,172 record holders of our common stock.



Dividend Policy. We have not paid
any cash dividends since our inception and do not contemplate paying dividends in the foreseeable future. We anticipate that earnings,
if any, will be retained for the operation of our business.



Securities Authorized for Issuance Under
Equity Compensation Plans.



This information is included under Item
12. Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters.



Page 26 of 132







Purchases of Securities by the Company



None.



Recent Sales of Unregistered Securities



During the past three years, we effected
the following transactions in reliance upon exemptions from registration under the Securities Act as amended. Unless stated otherwise;
(i) that each of the persons who received these unregistered securities had knowledge and experience in financial and business
matters which allowed them to evaluate the merits and risk of the receipt of these securities, and that they were knowledgeable
about our operations and financial condition; (ii) no underwriter participated in, nor did we pay any commissions or fees to any
underwriter in connection with the transactions; (iii) the transactions did not involve a public offerings; and (iv) each certificate
issued for these unregistered securities contained a legend stating that the securities have not been registered under the Act
and setting forth the restrictions on the transferability and the sale of the securities.



12%
Convertible Note Financing March and April 2010



On March 22, 2010, we entered into a Note
and Warrant Purchase Agreement with one accredited investor. Pursuant to the agreement, we issued the lender a 12% Convertible
Promissory Note (“Note”) in the principal amount of $925,000 and a five year warrant (“Warrant”) to purchase
up to 44,000 shares of our common stock with an exercise price of $7.00 per share. The Warrant is initially exercisable at the
higher of: (i) 105% of the average VWAP for the five trading days immediately preceding the date we issued the Warrant; and (ii)
the Floor Price (the same as in the Note) in effect on the date the Warrant is exercised. The Note carries a 20% original issue
discount. In addition, we agreed to pay $200,000 to the lender to cover their transaction costs incurred in connection with this
transaction; such amount was withheld from the loan at the closing of the transaction. As a result, the total net proceeds we received
were $540,000. We relied on the exemption from registration provided by Section 4(2) of the Securities Act of 1933, as amended
(the “Securities Act”), and Rule 506 promulgated thereunder. We believe that all of the purchasers are “accredited
investors,” as such term is defined in Rule 501(a) promulgated under the Securities Act. The conversion price of the Convertible
Promissory Note is equal to 80% of the volume-weighted average price for the 5 trading days ending on the business day immediately
preceding the applicable date the conversion is sought but will be at least $7.00 per share, subject to adjustment upon the occurrence
of certain events.



The transaction with the lender was the
“First Closing” of a series of similar transactions in April 2010, which together are hereinafter referred to as “2010
Convertible Note Financing.” On April 8, 2010, the Board of Directors authorized the Company to enter into additional Purchase
Agreements to issue up to an additional $7,500,000 of 12% Convertible notes and to issue warrants to issue up to an additional
600,000 shares of the Company’s common stock pursuant to the 2010 Convertible Note Financing.



On April 8, 2010, we entered into Note
and Warrant Purchase Agreements (the “Agreements”) with 24 accredited investors (“Lenders”) in the “Second
Closing” of the sale of 12% Convertible Notes (“Second Closing Notes”) and Warrants. Pursuant to the Agreements,
we issued to the Lenders Convertible Promissory Notes in the aggregate principal amount of $5,490,165 and warrants to purchase
up to 261,129 shares of our common stock (“Warrants”) with an exercise price of 9.50 per share. The Second Closing
Notes mature on April 7, 2011 (“Maturity Date”). The Second Closing Notes contain original issue discounts and fees
payable by us aggregating $2,285,165. As a result, the total net proceeds we received were $3,205,000. The Agreements, Notes and
Warrants, as well as the terms of this transaction, are substantially the same as those we issued to the investor in the First
Closing on March 22, 2010, as disclosed in the Current Report on Form 8-K that we filed with the Securities and Exchange Commission
on March 26, 2010.



As of the Second Closing, we had 1,074,043
shares of common stock issued and outstanding. The Agreements include an addendum that prohibits us from issuing more than 23,781
shares to the Lenders, unless we receive stockholder approval and NYSE Amex approval to list and issue all shares issuable: (i)
upon exercise of all of the Warrants at $9.50 per share, (ii) all of the Notes are converted at that same price (which is the lowest
price possible, although the initial conversion price is 80% of the five day volume weighted average closing price of our common
stock preceding the date of conversion) and (iii) no shares are issued in payment of interest. We are required under the terms
of the Notes to obtain stockholder approval, on or before July 15, 2010, of the issuance of all shares of our common stock issuable
pursuant to the Notes and Warrants. If we fail to obtain such approval, an Event of Default under the Notes shall occur. We are
also obligated to receive listing approval from NYSE Amex for the shares of common stock issuable upon conversion of the Note and
exercise of the Warrant as soon as practicable after closing, but in no event later than May 1, 2010.



Page 27 of 132







On April 13, 2010, we entered into Additional
Note and Warrant Purchase Agreements (“Additional Agreements”) with eleven accredited investors (“Lenders”)
in a “Third Closing” of the 2010 Convertible Note Financing. Pursuant to the Additional Agreements, we issued to the
Lenders additional Convertible Promissory Notes in the aggregate principal amount of $3,957,030 (“Third Closing Notes”)
and warrants to purchase up to 188,226 shares of our common stock (“Warrants”). The Third Closing Notes mature on April
12, 2011 (“Maturity Date”). The conversion price of the Third Closing Notes is the highest of (i) 80% of the five day
volume weighted average closing price of our common stock preceding the date of conversion, or (ii) $7.00 per share. We agreed
to pay to the Lenders one-sixth of the principal amount of the Notes each month commencing on the six month anniversary of the
Notes and the balance of the unpaid principal of the Notes on the one year anniversary date of the Notes. The Notes contain original
issue discounts and fees payable by us aggregating $1,647,030. As a result, the total net proceeds we received in the Third Closing
were $2,310,000. The exercise price of the Warrants issued in the third closing is $9.50 per share.



On April 26, 2010, in the “Fourth
Closing,” other accredited investors purchased an aggregate of $685,170 of principal amount of 12% Convertible Notes (“Fourth
Closing Notes”) and the Company issued additional warrants to purchase an aggregate of 32,592 shares of the Company’s
common stock on terms substantially the same as the First Closing, Second Closing and Third Closing. As part of the Fourth Closing,
investors in the 2009 Registered Direct Offering exercised their Right of Participation” and purchased $599,525 of Notes
and the Company issued to them warrants to purchase 28,518 shares of the Company’s common stock exercisable at $7.00 per
share. The warrants sold to the new investors in the Fourth Closing are exercisable at $22.25 per share. The net proceeds from
the Fourth Closing were approximately $400,000.



The Agreements, Notes and Warrants, as
well as the terms of this transaction (other than the exercise price of the warrants) in the Second Closing, Third Closing and
Fourth Closing, are substantially the same as those we issued to the investor in the First Closing pursuant to the Note and Warrant
Purchase Agreements we entered into on March 22, 2010.



We are required under the terms of the
Notes to obtain stockholder approval, on or before August 31, 2010, of the issuance of all shares of our common stock issuable
pursuant to the Notes and Warrants in this financing. If we fail to obtain such approval, an Event of Default under the Notes shall
occur. We are also obligated to receive listing approval from NYSE Amex for the shares of common stock issuable upon conversion
of the Note and exercise of the Warrant as soon as practicable after Closing, but in no event later than May 1, 2010. A listing
application will be prepared and filed with the NYSE Amex.



Any shares of common stock issuable in
any of the Closings in excess of NYSE Amex Rule 713 so-called “19.99% Cap” required stockholder approval. After various
defaults on the 2010 Notes and related forebearance agreements and settlement discussions, as of December 31, 2011, the entire
outstanding principal amount of the notes issued pursuant to the 2010 Convertible Note Financing was converted into common stock.



January 2011 Financing



On January 30, 2011 we entered into a securities
purchase agreement with 5 accredited investors (the “2011 Noteholders”) for a private financing (the “January
2011 Financing”). We closed the financing contemplated by the securities purchase agreement on January 31, 2011 and received
approximately $7,500,000 in gross proceeds pursuant to the sale of convertible notes pursuant to the securities purchase agreement.
Net proceeds from the financing were approximately $6,820,000. In connection with the closing of the transactions, we issued Convertible
Promissory Notes in the aggregate principal amount of $8,437,500 (the “Notes”), at a purchase price of $888.88 for
each $1,000 of principal amount of Notes, which are initially convertible into an aggregate of 562,500 shares of our common stock
(“Note Shares”) to the Investors, and the Investors also received: (i) Series A Warrants (“Series A Warrants”)
to purchase an aggregate of 562,500 shares of our common stock (“Series A Warrant Shares”) at an initial exercise price
of $16.75 per share and (ii) Series B Warrants (“Series B Warrants,” together with the Series A Warrant, the Warrants’)
to purchase an aggregate of 281,250 shares of our common stock (the “Series B Warrant Shares,” together with the Series
A Warrant Shares, the “Warrant Shares”) at an initial exercise price of $20.44 per share for their investment. Each
of the Warrants has a term of five (5) years from the date the Warrants are initially exercisable. For further information about
the Notes and the Warrants, we direct your attention to the Current Report on Form 8-K that we filed with the SEC on January 31,
2011.



Page 28 of 132







Reedland Capital Partners, an Institutional
Division of Financial West Group, member FINRA/SIPC, served as the placement agent and financial advisor in connection with this
financing. In connection with this financing, we paid cash compensation to Reedland in the amount of $500,000 and issued them warrants
to purchase up to an aggregate of 33,852 shares of our common stock warrants at an exercise price of $16.75 per share. Each of
Reedland’s warrants is exercisable for a period of 5 years.



On August 1, 2011, first determination
date, the exercise price for 33,852 Placement Agent warrants issued in connection with January 2011 financing was reduced to $0.05
per share. The adjustment is effective August 15, 2011 and was made pursuant to the original contractual agreement and is calculated
on the first day the securities may be resold without restriction or limitation pursuant to Rule 144. If the arithmetic average
of the Weighted Average Prices for each of the ten (10) Trading Days immediately following the First Determination Date (the "First
Adjustment Price") is less than the then existing Exercise Price, then on the tenth (10th) Trading Day following the First
Determination Date, the Exercise Price then in effect shall be reduced (but in no event increased) to the First Adjustment Price.
The warrants are accounted for as derivatives and the modification of the exercise price was captured though the binomial valuation
process and recorded as a change in fair value of derivative liabilities.



On November 30, 2011, the exercise price
for the 33,852 warrants outstanding in connection with placement agent was further adjusted to approximately $0.06, and the number
of the warrants increased to 751,950. The adjustment was made pursuant to the down round provisions of the original contractual
agreement and was triggered by consideration received for November 30, 2011 exercise of the Series B warrants issued in connection
with November 2011 exchange. The warrants are accounted for as derivatives and the modification of the exercise price and number
of the warrants was captured though the binomial valuation process, with the effect recorded in change in fair value for the period.



The January 2011 Financing was made pursuant
to the exemption from the registration provisions of the Securities Act of 1933, as amended, provided by Section 4(2) of the Securities
Act and Rule 506 of Regulation D promulgated hereunder. The securities issued have not been registered under the Securities Act
and may not be offered or sold in the United States absent registration or an applicable exemption from registration requirements.



We were required to pay a certain portion
of the Notes (“Installment Amount”) back on the first day of each month during the term of the Note, beginning on March
1, 2011, in cash or shares of our common stock. As of May 1, 2011, the outstanding principal of the Notes was $6,750,000. The total
Installment Amount due on May 1, 2011 was $843,750. We are also required under the terms of the Notes to maintain a cash balance
at all times of no less than $2,250,000 in unrestricted cash (the “Cash Reserve”). The May 1 Installment Amount would
have caused our cash balance to go below the Cash Reserve; accordingly we did not make the Installment Amount that was due on May
1, 2011, which is an event of default under the Notes.



Upon the occurrence of an event of default
under the Note, the Note holder has the right to force us to redeem all or any portion of such holder’s Note in cash. As
of May 10, 2011, we received redemption notices from all of the investors of the financing demanding to redeem the entire amount
outstanding on the Notes as of May 1, 2011. Accordingly, we were required to pay $8,618,311 pursuant to the redemption notices
and such payment is due within 5 business days of receipt of such notices. Based on when we received the redemption notices, we
were required to pay one investor on May 9, 2011 and the remaining 4 investors on or before May 12, 2011.



The amount listed above includes the required
late charge equal to interest on the May Installment Amount at the rate of 24% per annum from May 1, 2011 through May 10, 2011;
however, such interest will accrue until the date we pay the amount due. Additionally, we were required to pay a registration delay
payment of 1.5% of the aggregate purchase price each month until the registration statement registering the shares of common stock
underlying the notes and warrants issued pursuant to the financing is declared effective.



In furtherance of our efforts to reserve
cash for our operations rather than the repayment of debt, we sought an amicable solution with the 2011 Noteholders regarding the
default and payment owed. To that end, we entered into an exchange agreement on June 29, 2011, with each of the 2011 Noteholders
(the “Exchange Agreement”) in order to settle our obligations to each of them.



Page 29 of 132







Pursuant to the terms of the Exchange Agreement,
each 2011 Noteholder agreed to exchange its claims against the Company, its subsidiaries and certain of their respective current
and former officers, directors and representatives for (i) the Company’s 4% convertible notes ($4,950,000 original principal
amount in the aggregate (the “4% Notes”), (ii) shares of 4% Series A Convertible Preferred Stock of the Company (with
an aggregate stated value of $6,701,000 (the “Preferred Stock”)) under a Certificate of Designations of Series A Convertible
Preferred Stock (the “Certificate of Designations”), and (iii) a warrant, expiring 5 years from the date of the receipt
of Stockholder Approval (as defined in the Exchange Agreement), to purchase additional shares of our common stock (3,778,725 shares
of common stock in the aggregate under all the warrants (the “Warrants”) together with the 4% Notes and Preferred Stock,
the “Initial Settlement Securities”). Under the Exchange Agreement, each of the 2011 Noteholders and their affiliated
and related persons and entities also received a mutual full release from the Company. Following a fairness hearing held on June
30, 2011, in the Supreme Court of the State of New York (the “Court”), the Court entered an order approving (i) the
fairness of the terms and conditions of the proposed exchange and the transactions contemplated by the Exchange Agreement, (ii)
the terms and conditions of the proposed exchange and the transactions contemplated by the Exchange Agreement and (iii) the issuance
of the Notes, the shares of Preferred Stock and the Warrants pursuant to the exemption from registration under Section 3(a)(10)
of the Securities Act of 1933, as amended (the “3(a)(10) Order”).



On August 1, 2011, the 4% Notes were amended
and waivers were given with respect to the Preferred Stock as disclosed in the Current Report on Form 8-K filed with the Securities
and Exchange Commission on August 2, 2011. On August 26, 2011, we further amended the 4% Notes to change the installment payment
dates under the 4% Notes to August 22, 2011, October 4, 2011, and November 4, 2011, and additional waivers were given with respect
to the automatic conversion dates under the Preferred Stock so that the automatic conversions were permitted to also occur on August
22, 2011, October 4, 2011, and November 4, 2011. Additionally, the Maturity Date of the Note was changed to December 8, 2011, and
waivers were given with respect to the Preferred Stock so that the final automatic conversion occurred on December 8, 2011. All
of the foregoing amendments made, and waivers given, on August 26, 2011 were disclosed in a Current Report on Form 8-K filed with
the SEC on August 29, 2011.



Due to the occurrence of various events
of defaults under the 4% Notes and triggering events under the Preferred Stock, the Company determined it was in its best interest
to enter into another exchange agreement with the 2011 Noteholders. Accordingly, on November 28, 2011, we entered into the November
Exchange Agreements with each 2011 Noteholders, as more fully explained under Item 3. Legal Proceedings above.



The transactions contemplated by the November
Exchange Agreements were consummated on November 28, 2011 and the securities issued pursuant thereto are exempt from the registration
requirements of the 1933 Act pursuant to Section 3(a)(9) thereof because such securities are being exchanged by the Company with
existing security holders exclusively where no commission or other remuneration is paid or given directly or indirectly for soliciting
such exchange.



On May 15, 2012, we completed an agreement
with the 2011 Noteholders, severally and not jointly, for the exercise of an aggregate of $150,000 worth of our Series A Common
Stock Purchase Warrants at an exercise price of $0.02619 per share, pursuant to which we issued an aggregate of 5,727,376 shares
of our common stock. The proceeds received from such Warrant exercise, shall be used solely and exclusively to enable us to keep
our Registration Statement on Form S-1 filed under the Securities Act of 1933, as amended, which the Securities and Exchange Commission
declared effective on February 14, 2012, current and maintain compliance with our reporting requirements under the Securities Exchange
Act of 1934, as amended.



Non-Cash Activities



None of the below transactions involved
a public offering, and unless otherwise noted below, we believe that each transaction was exempt from the registration requirements
of the Securities Act by virtue of Section 4(2) of the Securities Act or Rule 506 of Regulation D as promulgated by the SEC.



On January 22, 2009, the Company granted
B&D Consulting 16,000 shares of the Company’s common stock in exchange for services, vesting over a period of 24 months.
A total of 667 and 8,000 of common stock shares were vested during the years ended December 31, 2011 and 2010, respectively. In
accordance with relevant accounting guidance, the shares are valued as they are earned monthly, as such, the Company recorded general
and administrative expense of $10,167 and $137,638, for the years ended December 31, 2011 and 2010, respectively related to this
agreement.



Page 30 of 132







On September 10, 2009, the Company entered
into a consulting agreement (the “Consulting Agreement”) with Cantone Asset Management, LLC (“Cantone Asset”)
whereby Cantone Asset provided guidance and advice related to negotiating the terms of the Company’s outstanding Series 1
and Series 2 Senior Notes and continued services to assist the Company to coordinate with the holders of the Series 1 and Series
2 Senior Notes (see Note 8). We agreed to increase the cash fee owed to Cantone Asset by 25% to a total owed of $180,000, and instead
of paying the amount owed in cash we agreed to issue them 25,714 shares of the Company’s common stock as full payment of
the amount owed, subject to NYSE Amex approval. NYSE Amex approved the shares on January 3, 2011 and the shares were issued in
January 2011. The expense of $180,000 for the consulting agreement was recorded to general and administrative expense in the accompanying
condensed consolidated statement of operations for the year ended December 31, 2011.



On September 22, 2009, the Company entered
into an agreement with Lyons Consulting for investor relations services through September 2010. The Company granted Lyons Consulting
8,000 restricted shares of the Company’s common stock in exchange for services. In accordance with FASB ASC 505-50, the shares
issued are periodically valued through the vesting period. The shares were approved by the NYSE Amex US on December 10, 2009. During
the year ended December 31, 2010 4,000 shares were earned. The Company recorded $74,500 related to the vested shares during the
year ended December 31, 2010.



On November 11, 2009, the Company entered
into an agreement with First International Capital Group, Ltd., to provide investor relations services. In connection with the
agreement, the Company issued a total of 36,000 shares of the Company’s common stock. The service term was six months (commencing
November 24, 2009 and ending May 25, 2010). The value of the common shares using the stock price on date of commencement was $6.00
per share. The total value of $360,000 was recorded as prepaid consulting expense and was amortized over the service period of
six months. During the year ended December 31, 2010, the Company amortized $300,000, as general administrative expenses related
to this agreement.



On January 7, 2010, the Company entered
into an agreement for the issuance of 4,000 shares of common stock to Boston Financial Partners for financial advisory services
to be provided for the period January 1, 2010 through July 1, 2010. The shares vest ratably over the seven month period. The issuance
of the shares was contingent upon NYSE Amex Approval. NYSE Amex Approval was received in April 8, 2010. Therefore, the shares for
compensation were measured and recorded on the date the Company received NYSE Amex approval and the Company recorded prepaid consulting
of $71,000 related to the agreement. The shares were amortized to expense over the service period during the year ended December
31, 2010.



On January 13, 2010, the Company entered
into an agreement with B&D Consulting for investor relations services through June 13, 2010. The Company granted B&D Consulting
8,000 shares of the Company’s common stock in exchange for services. In accordance with FASB ASC 505-50, the shares issued
are periodically valued, as earned, through the vesting period. The shares were earned during the year ended December 31, 2010,
and the Company recorded general and administrative expense of $108,000 related to the agreement.



On January 13, 2010, the Company entered
into an agreement with Catawaba LTD (“Catawaba”) for investor relations services through September 13, 2010. The Company
granted Catawaba 36,000 shares of the Company’s common stock in exchange for services which were valued at $288,000 and was
recorded as prepaid consulting expense. The prepaid consulting expense was amortized to consulting expense ratably over the service
period. During the year ended December 31, 2010, the Company amortized $288,000 related to the consulting agreement, as general
and administrative expenses related to the agreement.



On February 5, 2010, the Company entered
into an agreement for the issuance of 19,200 shares of common stock to Garden State Securities pursuant to a consulting agreement
for consulting services to be provided from February 5, 2010 through February 5, 2011. The issuance of the shares was contingent
upon NYSE Amex Approval. NYSE Amex approval was received on April 8, 2010. In accordance with FASB ASC 505-50, the shares issued
are periodically valued, as earned, through the vesting period. The Company recorded $85,200 as prepaid consulting expenses for
the initial 4,800 shares that were to be vested over three months and the remaining shares were expensed when earned. During the
years ended December 31, 2010, and 2011, 18,827 and 373, respectively, shares were earned. The Company recorded general and administrative
expense of $352,440 and $7,466 during the years ended December 31, 2010, and 2011, respectively, related to the agreement.



On February 9, 2010, the Company entered
into an agreement for the issuance of 36,000 shares of common stock to LWP1 pursuant to a consulting agreement for financial advisory
services to be provided from February 9, 2010 through November 9, 2010. The shares vested over a ten month period as follows: 18,000
on February 9, 2010 and 2,000 each month thereafter, through the vesting term. The issuance of the shares was contingent upon NYSE
Amex approval. NYSE Amex Approval was received on April 8, 2010. In accordance with FASB ASC 505-50, the shares issued are periodically
valued, as earned, through the vesting period. The Company recorded $319,500 as prepaid consulting expenses for the initial 18,000
shares that were to be vested over three months and the remaining shares were expensed when earned. During the year ended December
31, 2010, all 36,000 shares were earned. The Company recorded general and administrative expense of $670,333 during the year ended
December 31, 2010 related to the agreement.



Page 31 of 132







On February 22, 2010, the Company agreed
to issue 6,429 shares of common stock to settle an unpaid invoice in the amount of $45,000 of accounts payable through the date
of the agreement, subject to NYSE Amex Approval. NYSE Amex approval was received on April 8, 2010 and the Company recorded the
common stock issuance of $45,000 based on stock price on such date.



On March 1, 2010, the Company entered into
an agreement for the issuance of 28,800 shares of common stock to JFS Investments pursuant to a consulting agreement for financial
advisory services to be provided through February 28, 2011. The issuance of the shares was contingent upon NYSE Amex approval.
NYSE Amex approval was received on April 8, 2010. In accordance with FASB ASC 505-50, the shares issued are periodically valued,
as earned, through the vesting period. The Company recorded $127,800 as prepaid consulting expenses for the initial 7,200 shares
that were to be vested over three months and the remaining shares were expensed when earned. During the years ended December 31,
2010 and 2011, 25,840 and 2,960, respectively, shares were earned. The Company recorded general and administrative expense of $472,260
and 47,600 during the year ended December 31, 2010 and 2011, respectively, related to the agreement.



On April 13, 2010, the Company entered
into an agreement with Lyons Consulting for investor relation services through October 2010. The Company granted Lyons Consulting
8,000 shares of the Company’s common stock in exchange for services. The shares were approved by the NYSE Amex US on October
15, 2010, at which time the Company valued the shares at $16.5 per share. The Company recorded general and administrative expense
of $132,000 during the year ended December 31, 2010 related to the agreement.



On May 10, 2010, the Company entered into
an agreement with Uptick Marketing for marketing services through August 2010. The Company granted Uptick Marketing 10,000 shares
of the Company’s common stock in exchange for services. The shares were approved by the NYSE Amex US on October 15, 2010,
at which time the Company valued the shares at $16.5 per share. The Company recorded general and administrative expense of $165,000
during the year ended December 31, 2010 related to the agreement.



On August 1, 2010, the Company entered
into an agreement with Catawaba Global LTD (“Catawaba”) for investor relations services through May 1, 2011. The Company
granted Catawaba 8,000 shares of its common stock in exchange for services. The shares were approved by the NYSE Amex US on December
3, 2010. The shares and were valued at $78,000 and recorded as prepaid consulting expense. The prepaid consulting expense was amortized
to consulting expense ratably over the service period. During the year ended December 31, 2010 and 2011 the Company amortized $43,333
and $34,667, respectively, related to the consulting agreement.



On August 1, 2010, the Company entered
into an agreement with First International Capital Group, LTD (“First International”) for investor relations services
through Feb 1, 2011. The Company granted First International 8,000 shares of its common stock in exchange for services. The shares
were approved by the NYSE Amex US on December 3, 2010. The shares were valued at $78,000 and recorded as prepaid consulting expense.
The prepaid consulting expense was amortized to consulting expense ratably over the service period. During the years ended December
31, 2010 and 2011, the Company amortized $65,000 and $13,000, respectively, related to the consulting agreement.



On August 1, 2010, the Company entered
into an agreement for the issuance of 19,200 shares of common stock to Garden State Securities pursuant to a consulting agreement
for consulting services to be provided from August 1, 2010 through August 1, 2011. NYSE Amex approval was received on December
3, 2010. During the years ended December 31, 2010 and 2011, 8,000 and 11,200, respectively, shares were earned. The Company recorded
general and administrative expense of $78,000 and $153,287 during the year ended December 31, 2010 and 2011, respectively, related
to the agreement.



On August 1, 2010, the Company entered
into an agreement for the issuance of 28,800 shares of common stock to JFS Investments pursuant to a consulting agreement for consulting
services to be provided from August 1, 2010 through August 1, 2011. NYSE Amex approval was received on December 3, 2010. During
the year ended December 31, 2010 and 2011, 12,000 and 16,800, respectively, shares were earned. The Company recorded general and
administrative expense of $90,000 and $188,620, during the year ended December 31, 2010 and 2011, respectively, related to the
agreement.



Page 32 of 132







On January 1, 2011, we entered into an
agreement for the issuance of 10,000 shares of common stock to Cantone Asset Management pursuant to a consulting agreement for
consulting services to be provided from January 1, 2011 through December 31, 2011. The issuance of the shares was subject to NYSE
Amex approval, and as such approval had not been received, the shares were not issued. On June 23, 2011, we became listed on the
OTCQX exchange, and therefore, no longer required NYSE Amex approval. Due to the unavailability of authorized shares, the 10,000
shares were issued on January 6, 2012 (see Note 16). The shares were valued at $3.75 per share, the closing bid price for shares
of our common stock on the date the Company’s common stock began trading on the OTCQX. The Company recorded general and administrative
expense of $37,500 during the year ended December 31, 2011 related to the agreement.



On April 27, 2011, we entered into an agreement
with Catawaba Global LTD (“Catawaba”) for investor relations services through December 31, 2011. We granted Catawaba
30,000 shares of our common stock in exchange for services. On November 21, 2011, we entered into an amendment agreement with Catawaba
Global LTD (“Catawaba”) for investor relations services through October 31, 2012, pursuant to which we would issue
them an aggregate of 1,400,000 shares in exchange for their services. As of December 31, 2011, a total of 788,333 shares of common
stock were earned under the terms of the contract and the Company has recorded an aggregate of $463,458 as consulting expense in
selling, general and administrative expenses. In accordance with the agreement and relevant accounting guidance, the remaining
of 641,667 shares shall be expensed in monthly installments, when the shares are vested and earned in the subsequent periods. Due
to the unavailability of authorized shares, the 1,430,000 shares were issued on January 6, 2012 (See Note 16 Subsequent Events).



On May 1, 2011, we entered into an agreement
with First International Capital Group, LTD (“First International”) for investor relations services through December
31, 2011. We granted First International 30,000 shares of our common stock in exchange for services. On November 21, 2011, we entered
into an amendment agreement with First International Capital Group, LTD (“First International”) for investor relations
services through October 31, 2012, pursuant to which we would issue them an aggregate of 1,400,000 shares in exchange for their
services. As of December 31, 2011, a total of 788,333 shares of common stock were earned under the terms of the contract and the
Company has recorded an aggregate of $463,458 as consulting expense in selling, general and administrative expenses. In accordance
with the agreement and relevant accounting guidance, the remaining of 641,667 shares shall be expensed in monthly installments,
when the shares are vested and earned in the subsequent periods. Due to the unavailability of authorized shares, the 1,430,000
shares were issued on January 6, 2012 (See Note 16 Subsequent Events).



On June 1, 2011, we entered into an agreement
for the issuance of 32,000 shares of our common stock to Garden State Securities pursuant to a consulting agreement for consulting
services to be provided through December 31, 2011. On November 21, 2011, we entered into an amendment agreement with Garden State
Securities for investor relations services through October 31, 2012, pursuant to which we would issue them an aggregate of 3,000,000
shares in exchange for their services. As of December 31, 2011, a total of 1,657,000 shares of common stock were earned under the
terms of the contract and the Company has recorded an aggregate of $438,125 as consulting expense in selling, general and administrative
expenses. In accordance with the agreement and relevant accounting guidance, the remaining of 1,375,000 shares shall be expensed
in monthly installments, when the shares are vested and earned in the subsequent periods. Due to the unavailability of authorized
shares, the 3,032,000 shares were issued on January 4, 2012 (See Note 16 Subsequent Events).



On June 1, 2011, as later amended on August
7, 2011, we entered into an agreement for the issuance of 72,000 shares of common stock to JFS Investments pursuant to a consulting
agreement for consulting services to be provided through May 31, 2012. On November 21, 2011, we entered into an amendment agreement
with JFS Investments for investor relations services through October 31, 2012, pursuant to which we would issue them an aggregate
of 4,000,000 shares in exchange for their services. As of December 31, 2011, a total of 2,208,667 shares of common stock were earned
under the terms of the contract and the Company has recorded an aggregate of $440,967 as consulting expense in selling, general
and administrative expenses. In accordance with the agreement and relevant accounting guidance, the remaining of 1,863,333 shares
shall be expensed in monthly installments, when the shares are vested and earned in the subsequent periods. On December 15, 2011,
we issued an aggregate of 1,400,000 shares of common stock to consultant. Due to the unavailability of authorized shares, we issued
the balance of 2,672,000 shares on January 6, 2012 (See Note 16 Subsequent Events).



Page 33 of 132







On August 1, 2011, we entered into an agreement
for the issuance of 12,000 shares of common stock to Galileo Asset Management (“Galileo”) pursuant to a consulting
agreement for consulting services to be provided through December 31, 2011. On November 21, 2011, we entered into an amendment
agreement with Galileo for investor relations services through October 31, 2012, pursuant to which we would issue them an aggregate
of 400,000 shares in exchange for their services. As of December 31, 2011, a total of 228,667 shares of common stock were earned
under the terms of the contract and the Company has recorded an aggregate of $47,523 as consulting expense in selling, general
and administrative expenses. In accordance with the agreement and relevant accounting guidance, the remaining of 183,333 shares
shall be expensed in monthly installments, when the shares are vested and earned in the subsequent periods. Due to the unavailability
of authorized shares, the 412,000 shares were issued in January 2012 (See Note 16 Subsequent Events).



On August 20, 2011, we entered into an
agreement for the issuance of 48,000 shares of common stock to Brighton Capital (“Brighton”) pursuant to a consulting
agreement for consulting services to be provided through July 15, 2011. On November 21, 2011, we entered into an amendment agreement
with Brighton for investor relations services through October 31, 2012, pursuant to which we would issue them an aggregate of 4,000,000
shares in exchange for their services. As of December 31, 2011, a total of 2,214,667 shares of common stock were earned under the
terms of the contract and the Company has recorded an aggregate of $520,167 as consulting expense in selling, general and administrative
expenses. In accordance with the agreement and relevant accounting guidance, the remaining of 1,833,333 shares shall be expensed
in monthly installments, when the shares are vested and earned in the subsequent periods. On December 15, 2011, we issued an aggregate
of 1,448,000 shares of common stock to consultant. Due to the unavailability of authorized shares, we issued the balance of 2,600,000
shares on January 6, 2012 (See Note 16 Subsequent Events).



On October 1, 2011, the Company entered
into an agreement for marketing services through December 31, 2012 with OTT Enterprises LLC (“OTT”). On November 1,
2011, the Company granted to OTT three years 4,000,000 warrants, with $.175 exercise price, with a cashless provision effective
after 1 year if no Registration Statement is filed to register the underlying shares. The consultant has a beneficial ownership
limit of 9.99%. Also, has resale volume restrictions (as % of aggregate trading volume of the Company common stock) as follow:
for Trading Day preceding sale and a stock price between $0-$1.25 than 12.5%, $1.25-$2.5 than 25%, $2.5-$3.75 than 37.5%. The warrant
was valued using Black Scholes Options Pricing Model to $728,907 and the value is amortized over the life of the agreement. As
of December 31, 2011, the Company has recorded an aggregate of $145,781 as consulting expense in selling, general and administrative
expenses. (See Note 16 Subsequent Events).



As previously disclosed, Alpha Capital
Anstalt (“Alpha Capital”) and Whalehaven Capital Fund Ltd (‘Whalehaven”, and together with Alpha Capital,
collectively the "Plaintiffs") filed a complaint against us regarding the number of warrants Plaintiffs received in a
registered direct offering we completed in November 2009 and the shareholder vote we obtained at our December 3, 2010 annual shareholder
meeting. As later reported, on May 10, 2011, we entered into a Settlement Agreement with the Plaintiffs pursuant to which we agreed
to issue that number of shares of our common stock equal in value to $10,912,055 at the time of issuance, which shares were evidenced
in part by convertible promissory notes issued to the Plaintiffs. Such Settlement Agreement, as amended on May 23, 2011 (the “Original
Settlement Agreement”), was approved by the United States District Court for the Southern District of New York (the “Court”)
which issued an order providing that the common stock issuable under the notes were exempt securities under Section 3(a)(10) of
the Securities Act of 1933, as amended. As further reported, on July 19, 2011 the Plaintiffs wrote a letter to the Court that we
failed to perform our obligations under the Original Settlement Agreement, which allegations we have been disputed. Pursuant thereto,
to avoid litigation, on August 25, 2011, we entered into new settlement agreement with Plaintiffs that amended and restated the
Original Settlement Agreement (the “Final Settlement Agreement”), which was approved by the Court on August 26, 2011.
Under the terms of the Final Settlement Agreement, we issued our 8% convertible promissory notes in the principal amount of $4,559,842.41
to Alpha Capital and $3,496,415.91 to Whalehaven (the “Notes”). (For a complete discussion of the Final Settlement
Agreement and Notes, please see the Current Report on Form 8-K that we filed on August 29, 2011.) Additionally, we agreed to issue
Plaintiffs additional Non-Restricted Shares (the “True Up Shares”) to adjust, based on the recent reductions in the
closing prices of our publicly trades shares, the number of shares we previously issued to the Plaintiffs in connection with prior
conversions of the notes we issued under the Original Settlement Agreement. We agreed to reserve an aggregate of 7 million shares
of authorized and previously unissued Common Stock for potential issuance to the Plaintiffs for issuance upon their conversion
of the Notes. We further agreed to keep a sufficient number of shares of Common Stock for purposes of enabling issuing all of the
Settlement Shares pursuant to the Final Settlement Agreement and the Notes. As of December 31, 2011, we have issued a total of
3,720,000 True-Up Shares to Alpha Capital and 2,196,000 True-Up Shares to Whalehaven. As of December 31, 2011, an aggregate of
44,400,232 shares are issuable to Plaintiffs, as follow: 24,758,988 True-Up Shares to Alpha Capital and 19,641,945 True-Up Shares
to Whalehaven (See Note 16 Subsequent Events).



Page 34 of 132







On or around December 23, 2011, we issued
an aggregate of 4,346,333 shares of our common stock to the holders of JPI convertible debentures as per the automatic exchange
provision contained therein for conversion of the $1 million guarantee and associated interest of $86,583. Following such issuance,
the JPI debentures are fully converted.



Item 6.Selected Financial Data



Not applicable.



Item 7. Management’s Discussion and Analysis of
Financial Condition and Results of Operations



Forward Looking Information



This report contains forward-looking statements
regarding our plans, expectations, estimates and beliefs. Actual results could differ materially from those discussed in, or implied
by, these forward-looking statements. Forward-looking statements are identified by words such as “believe,” “anticipate,”
“expect,” “intend,” “plan,” “will,” “may,” and other similar expressions.
In addition, any statements that refer to expectations, projections or other characterizations of future events or circumstances
are forward-looking statements. We have based these forward-looking statements largely on our expectations.



Forward-looking statements are subject
to risks and uncertainties, certain of which are beyond our control. Actual results could differ materially from those anticipated
as a result of the factors described in the “Risk Factors” and detailed in our other Securities and Exchange Commission
filings.



Because of these risks and uncertainties,
the forward-looking events and circumstances discussed in this report or incorporated by reference might not transpire. Factors
that cause actual results or conditions to differ from those anticipated by these and other forward-looking statements include
those more fully described in the “Risk Factors” section and elsewhere in this report.



The following discussion contains forward-looking
statements and involves numerous risks and uncertainties, including, but not limited to, those described in the "Risk Factors"
section of this report. Actual results may differ materially from those contained in any forward-looking statements.



The following discussion and analysis of
financial condition and results of operations relates to the operations and financial condition reported in the consolidated financial
statements of the Company for the years ended December 31, 2011 and 2010, and should be read in conjunction with such consolidated
financial statements and related notes included in this report.



The Company



Since November 2011, we have been experiencing
severe working capital shortages. To maintain current in our reporting requirements, we entered into an agreement with our 2011
Noteholders and RDO Noteholders to exercise outstanding warrants equal in amount to $150,000. However, such funds may only be used
for such reporting requirement maintenance. If we are unable to raise additional financing, increase sales of our product or complete
a business transaction that would improve our financial situation, we will be forced to cease operations and potentially declare
bankruptcy.



We are engaged in the research, development,
manufacture, sale and marketing of Onko-Sure®, a proprietary in-vitro diagnostic (IVD) cancer test kit. Onko-Sure® is sold
as a blood test for cancer in the Europe (CE Mark certified), India, Japan, Taiwan, Korea, Vietnam and in Chile (research use).
In the United States, it is cleared by the FDA only for the monitoring of colorectal cancer and is approved in Canada (by Health
Canada) for lung cancer detection and lung cancer treatment monitoring.



For fiscal year 2011 and 2010, the Company
generated approximately $314,000 and $232,000, respectively, in the sales of the Company’s Onko-Sure® IVD cancer diagnostic
test kits.



Subject to receipt of adequate
working capital financing, we hoped that revenues from Onko-Sure® would increase in 2012 as a result of initiatives
including outreach to healthcare professionals and the negotiation of additional distribution agreements anticipated to
expand the IVD cancer diagnostic test into key international markets. Due to the lack of funding, our plans on increasing our
distribution have been suspended until we receive adequate working capital financing,  we will not be able to implement our
distribution strategy at the rate we anticipate, which will have a materially adverse effect on anticipated
2012 revenues.



Page 35 of 132







As a result of our working capital
deficiencies, we have recently laid off a substantial portion of our work force and are currently operating on a minimal
basis with only  two employees and three former employee consultants. The current focus of our operations is to ensure that
our existing Onko-Sure® customers and any future customers are able to place orders and receive kits on a timely basis.
We have an Onko-Sure® production continuity arrangement in place with one vendor. At the current time, the Company
believes that it does not require any additional staff to perform this limited manufacturing, quality control and selling
process.



The Company appointed a committee of
three independent directors to assess available options open to the Company to enable us to continue operations, or find
a suitable merger candidate or buyer of our technology. Although our remaining sales team continues to work towards
completing pending and future sales of our Onko-Sure ® test kit, if these sales are not completed and we do not
otherwise raise additional funds in the immediate future, it is likely that we will be forced to cease all operations and
might seek protection from our creditors under the United States bankruptcy laws. To date, neither the Company, it’s
management or the committee has been able to resolve the default with our noteholder and/or establish a definitive plan to
revitalize the Company.



We manufacture our proprietary Onko-Sure®
cancer test kits at our licensed manufacturing facility located at 2492 Walnut Avenue, Suite 100, in Tustin, California. We are
an FDA approved Good Manufacturing Practices manufacturing facility. We maintain a current Device Manufacturing License issued
by the State of California, Department of Health Services, Food and Drug Branch.



We refocused our business on the development,
manufacture and marketing of advanced medical diagnostic products, including our Onko-Sure®, a proprietary in-vitro diagnostic
cancer test kit. During the second half of fiscal year 2009, we repositioned various business assets that we believed would enable
us to monetize the value of such assets either through new partnerships, separate potential IPO’s, or possible sales. These
assets include: (i) our 97.4% ownership in China-based pharmaceuticals business, Jade Pharmaceuticals Inc. (“JPI”);
and (ii) our 100% ownership of a proprietary cancer vaccine therapy technology: Combined Immunogene Therapy (“CIT”).
In connection with the deconsolidation of JPI, effective September 29, 2009, we reclassified JPI as a business investment, rather
than as a condensed consolidated operating subsidiary. As of December 31, 2010, we wrote off and have fully impaired our investment
in JPI. See accompanying financial statements for the year ended December 31, 2010.



On September 25, 2009, we changed our name
from “AMDL, Inc.” to “Radient Pharmaceuticals Corporation.” We believe Radient Pharmaceuticals as a brand
name has considerable market appeal and reflects our new corporate direction and branding statements.



Onko-Sure® Cancer Test Kit



On July 8, 2009, we changed the brand name
of ourin-vitro diagnostic cancer test fromDR-70 to the more consumer friendly, trademarked brand name “Onko-Sure®,”
which we believe communicates it as a high quality, innovative consumer cancer test. We are also installed a new tag line —
“The Power of Knowing” — which communicates to cancer patients and their physicians that the test is effective
in assessing whether a patient’s cancer is progressing during treatment or is in remission.



Our Onko-Sure® product is manufactured
at our Tustin, California based facility and is sold to third party distributors, who then sell directly to CLIA certified reference
laboratories in the United States (“US”) as well as clinical reference labs, hospital laboratories and physician operated
laboratories in the international markets.



Our Onko-Sure®in- vitro diagnostic
test enables physicians and their patients to effectively detect and/or monitor the treatment and recurrence of solid tumors by
measuring the accumulation of specific breakdown products in the blood called Fibrin and Fibrinogen Degradation Products (FDP).
Onko-Sure® is a simple, non-invasive blood test used for the detection and/or monitoring of 19 different types of cancer including:
colon, rectal, lung, stomach, tongue, ovarian, uterine, liver, pancreatic, bladder, brain, esophageal, hematological, breast, prostate,
cervical, thyroid, lymphoma and trophoblast cancers. We believe that Onko-Sure® can be a valuable diagnostic tool in the worldwide
battle against cancer, the second leading cause of death worldwide. Because the Onko-Sure® test kit is a non-invasive blood
test, we believe that there are no side effects of the administration of the test. As with other cancer diagnostic products, false
positive and false negative test results could pose a small risk to patient health if the physician is not vigilant in following
up on the Onko-Sure® test kit results with other clinically relevant diagnostic modalities. While the Onko-Sure®, like
other blood biomarker tests, could be helpful in cancer detection, the attending physician is required to use other testing methods
to confirm the type of cancer.



Page 36 of 132







We believe that Onko-Sure® has the
potential to be used as a general cancer screening test. We are involved with research conducted with CLIA Laboratories to expand
on the Clinical utility of Onko-Sure®.



In-Vitro Cancer Research and Development



During the year ended December 31, 2011,
we incurred expenses of $115,476 in research and development related to the Onko-Sure®, as compared to $673,918 for the same
period in 2010. These expenditures were incurred as part of our efforts to produce Onko-Sure® components which will increase
our manufacturing capacity, improve the existing Onko-Sure®.



During the year ended December 31, 2010,
the majority of expenses incurred were to fund:



| | · | Validation study to determine if Onko-Sure® can be utilized as
a general cancer screen for 10 to 20 different cancers in a CLIA laboratory developed test environment; and
| | - | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | Evaluate Onko-Sure® as an additional marker in an existing test
to determine if the addition will enhance and improve analytical performance.
| | - | ---------------------------------------------------------------------------------------------------------------------------------------------



Due to the lack of funding and in an
effort to conserve cash, we have as of the date of this report suspended all research and development. If we are successful
in obtaining additional financing in 2012, we will restart research and development focusing on additional research in
different cancer types, support research to continually improve our Onko-Sure® test kit.



In addition, if additional funding is received,
we will continue to research the validity of our next generation version of our current Onko-Sure® test kit. We anticipate
additional costs will be incurred to fund research, to expand on the clinical utility of Onko-Sure® and development costs associated
with entry into new markets.



Cancer Therapeutics



In 2001, we acquired the CIT technology,
which forms the basis for a proprietary cancer vaccine. Our CIT technology is a U.S. patented technology (patent issued May 25,
2004). The Cancer Therapeutics division is engaged in commercializing the CIT technology. To date, we have not generated any revenues
and incurred minimal expenses, mostly related to patent protection, for this technology. As of December 31, 2010, we fully impaired
the value of our intangible asset related to this technology.



In December 2010, we formed NuVax Therapeutics,
Inc. (“NuVax”) with Javia’s CEO Dr. Umesh Bhatia by creating a platform to expand the planned collaboration to
include significantly expanded clinical trials in multiple international locations and in the U.S., and the in-licensing of other
novel cancer fighting technologies. All rights to our CIT technology will be transferred to NuVax, currently our 100% wholly-owned
subsidiary. All further development and commercialization of CIT and other to-be licensed novel cancer fighting technologies will
be made at NuVax.



In January 2011, NuVax signed four exclusive
license agreements with the University of Florida Research Foundation, Inc. (“UFRF”), for the development and marketing
of a cancer therapeutic product developed by the UFRF. In July 2011, the UFRF terminated the agreements due to lack of funding.



On August 29, 2011, due to lack of funding
and activity, Umesh Batia resigned as CEO and Director of Nuvax. As of the date of this report, we have not generated any revenues
and incurred license termination fee expenses for NuVax. Until we can complete funding for NuVax, we will continue to have minimal
activity in NuVax.



Page 37 of 132







Critical Accounting Policies



Our consolidated financial statements have
been prepared in accordance with accounting principles generally accepted in the United States of America. The preparation of these
consolidated financial statements requires us to make estimates and judgments that affect the reported amounts of assets, liabilities,
revenues and expenses, and related disclosure of contingent assets and liabilities. We base our estimates on historical experience
and on various other assumptions that are believed to be reasonable under the circumstances, the results of which form the basis
of making judgments about the carrying values of assets and liabilities that are not readily apparent from other sources. Actual
results may differ from these estimates under different assumptions or conditions and the differences could be material.



We believe the following critical accounting
policies, among others, affect our more significant judgments and estimates used in the preparation of our consolidated financial
statements:



Inventories. Major components of
inventories are raw materials, packaging materials, direct labor and production overhead. Our inventories consist primarily of
raw materials and related materials, and are stated at the lower of cost or market with cost determined on a first-in, first-out
(“FIFO”) basis. We regularly monitor inventories for excess or obsolete items and make any valuation corrections when
such adjustments are needed. Once established, write-downs are considered permanent adjustments to the cost basis of the obsolete
or excess inventories. We write down inventories for estimated obsolescence or unmarketable inventory equal to the difference between
the cost of inventories and the estimated market value based upon assumptions about future demand, future pricing and market conditions.
If actual future demands, future pricing, or market conditions are less favorable than those projected by management, additional
write-downs may be required and the differences could be material. Such differences might significantly impact cash flows from
operating activities.



Sales Allowances. A portion of our
business is to sell products to distributors who resell the products to end customers. In certain instances, these distributors
obtain discounts based on the contractual terms of these arrangements. Sales discounts are usually based upon the volume of purchases
or by reference to a specific price in the related distribution agreement. We recognize the amount of these discounts at the time
the sale is recognized. Additionally, sales returns allowances are estimated based on historical return data, and recorded at the
time of sale. If the quality or efficacy of our products deteriorates or market conditions otherwise change, actual discounts and
returns could be significantly higher than estimated, resulting in potentially material differences in cash flows from operating
activities.



Allowance for Doubtful Accounts.
We maintain allowances for doubtful accounts for estimated losses resulting from the inability of our customers to make required
payments. The allowance for doubtful accounts is based on specific identification of customer accounts and our best estimate of
the likelihood of potential loss, taking into account such factors as the financial condition and payment history of major customers.
We evaluate the collectibility of our receivables at least quarterly. If the financial condition of our customers were to deteriorate,
resulting in an impairment of their ability to make payments, additional allowances may be required. The differences could be material
and could significantly impact cash flows from operating activities.



Valuation of Intangible Assets.
We evaluate the carrying value of our long-lived assets for impairment whenever events or changes in circumstances indicate that
such carrying values may not be recoverable. We use our best judgment based on the current facts and circumstances relating to
our business when determining whether any significant impairment factors exist. We consider the following factors or conditions,
among others, that could indicate the need for an impairment review:



| | · | significant under performance relative to expected historical or projected
future operating results;
| | - | ----------------------------------------------------------------------------------------------------



| | · | market projections for cancer research technology;
| | - | --------------------------------------------------



| | · | our ability to obtain patents, including continuation patents, on
technology;
| | - | -----------------------------------------------------------------------------



| | · | significant changes in our strategic business objectives and utilization
of the assets;
| | - | ---------------------------------------------------------------------------------------



| | · | significant negative industry or economic trends, including legal
factors; and
| | - | ------------------------------------------------------------------------------



| | · | potential for strategic partnerships for the development of our patented
technology.
| | - | ------------------------------------------------------------------------------------



Page 38 of 132







If we determine that the carrying values
of long-lived assets may not be recoverable based upon the existence of one or more of the above indicators of impairment, our
management performs an undiscounted cash flow analysis to determine if impairment exists. If impairment exists, we measure the
impairment based on the difference between the asset’s carrying amount and its fair value, and the impairment is charged
to operations in the period in which the long-lived asset impairment is determined by management. Based on our analysis, we determined
the intangible asset of the CIT technology was impaired and recorded an impairment charge for the remaining carrying value of this
long-lived asset as of December 31, 2010.



The carrying value of our investment in
JPI represented our 97.4 % ownership interest in JPI, accounted for under the cost method. The ownership interest is not adjusted
to fair value on a recurring basis. Each reporting period we assessed the fair value of our ownership interest in JPI in accordance
with FASB ASC 325-20-35 paragraphs 1A and 2. At least annually, we conduct an impairment analysis in accordance with the provisions
within FASB ASC 320-10-35 paragraphs 25 through 32.



Revenue Recognition. Revenues from
the sales of our products are recognized when persuasive evidence of an arrangement exists, title and risk of loss have passed
to the buyer, the price is fixed or readily determinable and collection is reasonably assured.



During 2010 and 2011, we entered into several
distribution agreements for various geographic locations with third parties. Under the terms of some of the agreements, we sell
products to the distributor at a base price that is the greater of a fixed amount (as defined in each agreement) or 50% of the
distributor’s invoiced Net Sales price (as defined) to its customers. The distributor is required to provide us quarterly
reconciliations of the distributor’s actual invoiced prices at which time the price becomes fixed and determinable by us.
Until the price is fixed and determinable, we defer the recognition of revenues under these arrangements.



Deferred Taxes. We record a valuation
allowance to reduce the deferred tax assets to the amount that is more likely than not to be realized. We have considered estimated
future taxable income and ongoing tax planning strategies in assessing the amount needed for the valuation allowance. Based on
these estimates, all of our deferred tax assets have been reserved.



Litigation. We account for litigation
losses in accordance with accounting principles generally accepted in the United States, (“GAAP”), loss contingency
provisions are recorded for probable losses at management’s best estimate of a loss, or when a best estimate cannot be made,
a minimum loss contingency amount is recorded. These estimates are often initially developed substantially earlier than when the
ultimate loss is known, and the estimates are refined each accounting period, as additional information is known. Accordingly,
we often are initially unable to develop a best estimate of loss; therefore, the minimum amount, which could be zero, is recorded.
As information becomes known, either the minimum loss amount is increased or a best estimate can be made, resulting in additional
loss provisions. Occasionally, a best estimate amount is changed to a lower amount when events result in an expectation of a more
favorable outcome than previously expected. Due to the nature of current litigation matters, the factors that could lead to changes
in loss reserves might change quickly and the range of actual losses could be significant, which could materially impact our consolidated
results of operations and cash flows from operating activities.



Share-Based Compensation Expense.
All issuances of our common stock for non-cash consideration have been assigned a per share amount equaling either the market value
of the shares issued or the value of consideration received, whichever is more readily determinable. The majority of non-cash consideration
received pertains to services rendered by consultants and others and has been valued at the market value of the shares on the measurement
date.



We account for equity instruments issued
to consultants and vendors in exchange for goods and services in accordance with ASC 505. The measurement date for the fair value
of the equity instruments issued is determined at the earlier of (i) the date at which a commitment for performance by the consultant
or vendor is reached or (ii) the date at which the consultant or vendor’s performance is complete. In the case of equity
instruments issued to consultants, the fair value of the equity instrument is recognized over the term of the consulting agreement.



We account for equity awards issued to
employees following ASC 718 which requires a public entity to measure the cost of employee services received in exchange for an
award of equity instruments, including stock options, based on the grant-date fair value of the award and to recognize the portion
expected to vest as compensation expense over the period the employee is required to provide service in exchange for the award,
usually the vesting period.



Page 39 of 132







Beneficial Conversion Feature. In
certain instances, we enter into convertible notes that provide for an effective or actual rate of conversion that is below market
value, and the embedded conversion feature does not qualify for derivative treatment (a “BCF”). In these instances,
we account for the value of the BCF as a debt discount, which is then amortized to expense over the life of the related debt using
the straight-line method which approximates the effective interest rate method.



Derivative Financial Instruments.
We apply the provisions of FASB ASC 815-10,Derivatives and Hedging (“ASC 815-10”). Derivatives within the scope
of ASC 815-10 must be recorded on the balance sheet at fair value. During the year ended December 31, 2010, we issued convertible
debt with warrants and recorded derivative liabilities related to a reset provision associated with the embedded conversion feature
of the convertible debt and a reset provision associated with the exercise price of the warrants. We compute the fair value of
these derivative liabilities on the grant date and various measurement dates using the Binomial Lattice option pricing model. Due
to the reset provisions within the embedded conversion feature and a reset provision associated with the exercise price of the
warrants, we have determined that the Binomial Lattice Model was most appropriate for valuing these instruments. During the year
2011, all the new convertible debt and preferred stock with warrants issued has same provision, and we used the Binomial Lattice
Model for valuing these instruments.



Accounting for Debt Modifications and
Extinguishments.If a debt modification is deemed to have been accomplished with debt instruments that are substantially different,
the modification is accounted for as a debt extinguishment in accordance with FASB ASC 470-50, whereby the new debt instrument
is initially recorded at fair value, and that amount is used to determine the debt extinguishment gain or loss to be recognized
and the effective rate of the new instrument. If the present value of the cash flows under the terms of the new debt instrument
is at least ten percent different from the present value of the remaining cash flows under the terms of the original instrument,
the modification is deemed to have been accomplished with debt instruments that are substantially different. If it is determined
that the present values of the original and new debt instruments are not substantially different, then a new effective interest
rate is determined based on the carrying amount of the original debt instrument and the revised cash flows.



Results of Operations



Year Ended December 31, 2011 Compared to Year Ended December
31, 2010



|                                                       |  | Year Ended December 31, |             |   | Difference |  
|------------------------------------------------------ |  | ----------------------- | ----------- | - | ---------- | -
|                                                       |  | 2011                    |             |   | 2010       |  
|                                                       |  |                         |             |   |            |  
|Net revenues                                           |  | $                       | 313,559     |   |            | $
|Cost of sales                                          |  | $                       | 51,776      |   |            |  
|Gross profit                                           |  |                         | 261,783     |   |            |  
|                                                       |  |                         |             |   |            |  
|Operating expenses:                                    |  |                         |             |   |            |  
|Research and development                               |  |                         | 115,476     |   |            |  
|Selling, general and administrative                    |  |                         | 10,116,691  |   |            |  
|Impairment of receivable from JPI                      |  |                         | -           |   |            |  
|Impairment of intangible assets                        |  |                         | -           |   |            |  
|Total operating expenses                               |  |                         | 10,232,166  |   |            |  
|                                                       |  |                         |             |   |            |  
|Loss from operations                                   |  |                         | (9,970,383  | ) |            |  
|                                                       |  |                         |             |   |            |  
|Other income (expense):                                |  |                         |             |   |            |  
|Interest expense                                       |  |                         | (56,562,089 | ) |            |  
|Other expense, net                                     |  |                         | (319        | ) |            |  
|Change in fair value of derivative liabilities         |  |                         | 37,204,639  |   |            |  
|Impairment on investment in JPI                        |  |                         | -           |   |            |  
|Loss on extinguishment of debt                         |  |                         | (45,031,825 | ) |            |  
|Loss on legal settlement                               |  |                         | (10,987,055 | ) |            |  
|Loss on guarantee                                      |  |                         | (840,237    | ) |            |  
|Total other expense, net                               |  |                         | (76,216,886 | ) |            |  
|Loss from operations before provision for income taxes |  |                         | (86,187,269 | ) |            |  
|Provision for income taxes                             |  |                         | -           |   |            |  
|Net loss                                               |  | $                       | (86,187,269 | ) |            | $



|
|




| | * | Percentage difference is over 100%
| | - | ----------------------------------



Page 40 of 132







Net Revenues



Net revenues for the year ended December
31, 2011 was $313,559 compared to $231,662 for the same period in 2010. This increase of 35% is due to increased orders for the
Onko-Sure® test kits. During fiscal 2011 and 2010, we had three and four customers, respectively which represented approximately
64% and 94%, respectively of our net revenues. For the year ended December 31, 2011 and 2010, two customers were based in the U.S.
and represented approximately 42% and 59%, respectively of our net revenues and one and two customers were based outside the U.S.
and represented approximately 22% and 35%, respectively of our net revenues. Revenues were primarily earned from the sale of Onko-Sure®
test kits. Due to the lack of funding, we suspended our marketing program which may have a negative impact on U.S. Sales. If additional
funding is received, our goal is to enter into additional exclusive or non-exclusive distribution agreements for various regions..



Our expectations concerning
future sales represent forward-looking statements that are subject to certain risks and uncertainties which could result in
sales below those achieved in previous periods. Sales of Onko-Sure® test kits in 2012 will be impacted by the suspension
of our marketing program due to the lack of funding. In addition, 2012 sales could be negatively impacted by potential
competing products, lack of adequate supply and overall market acceptance of our products. Also, given our severe working
capital deficiencies and the recent lay off of a substantial portion of our workforce, it is extremely likely that we will
not be able to continue to grow sales and will likely have difficulties meeting the requirements of existing customers.



We have a limited supply of one
of the key components of the Onko-Sure® test kit. The anti-fibrinogen-HRP is limited in supply and additional
quantities cannot be purchased. Currently, we have two lots remaining which are estimated to produce approximately 21,000
kits. In order to utilize in kits, we will need to purify and quality control the lots. We currently have enough purified and
quality checked anti-fibrinogen-HRP to manufacture 200 kits. We currently do not have funds necessary to perform this action.
If we are unable to locate additional funds, our ability to meet the requirements of existing customers and develop any new
customers will be greatly impacted and our 2012 sales will be materially affected.



Due to the lack of funding, we suspended
until additional funding can be obtained, research and development of alternatives or investigation of outsourcing alternatives
for the anti-fibrinogen-HRP. Even if additional funding is obtained and research and development is re-started, we cannot assure
that this anti-fibrinogen-HRP replacement will be completed.



Gross Profit



Gross profit increased approximately 41%
to $261,783 for the year ended December 31, 2011 from $185,337 for the year ended December 31, 2010 due to increased sales volume
of the Onko-Sure® test kit.



The major components of cost of sales include
raw materials, wages and salary and production overhead. Production overhead is comprised of depreciation of manufacturing equipment,
utilities and repairs and maintenance.



Research and Development



All research and development costs are
comprised of expanding our research and development of the Onko-Sure® test kit. During the year ended December 31, 2011, we
incurred $115,476 on research and development expenses related to the Onko-Sure® test kit, compared to $673,918 for the same
period in 2010. This is a decrease of approximately 83%. Our research and development expenses decrease due to the shortage of
cash flow in 2011.



Page 41 of 132







Prior to our extreme funding difficulties, we
expected research and development expenditures to increase during 2012 due to:



| | · | Search for and retain staff and consultants needed to re-start the
research and development process ;
| | - | -----------------------------------------------------------------------------------------------------



| | · | Additional costs involved with consultants and the research conducted
with CLIA Laboratories to expand on the clinical utility of Onko-Sure®;
| | - | ---------------------------------------------------------------------------------------------------------------------------------------------



| | · | Costs necessary to conduct additional clinical studies;
| | - | -------------------------------------------------------



| | · | Additional collaboration costs to cover validation of this product
for other types of cancers worldwide.
| | - | --------------------------------------------------------------------------------------------------------



However, given our working capital deficiencies
and inability to maintain our previous operations, it is extremely likely that we will not be able to launch these initiatives
in 2012. If additional funding is located, we will evaluate these programs on a case-by-case basis to determine the best use
of any new operational funding. Furthermore, our inability to continue our research and development activities will
negatively impact sales going forward.



Selling, General and Administrative



Selling, general and administrative expenses
were $10,116,690 for the year ended December 31, 2011 as compared to $9,882,737 in 2010.



Selling, general and administrative expenses
consist primarily of consulting (including financial consulting) and legal expenses, director and commitment fees, regulatory compliance,
patent protection, payroll, payroll taxes, investor and public relations, professional fees, and stock exchange and shareholder
services expenses.



Included in selling,
general and administrative expenses were non-cash expenses incurred during the years ended December 31, 2011 and 2010, respectively,
of $3,625,248 and $3,222,589 for common stock, options and warrants issued to consultants for services and $1,102,190 and $2,018,458
for options issued to employees and directors. The increase in selling, general and administrative expenses is primarily due to
increase of cash and noncash expenses of marketing, investor relations and secondarily due to increased accounting and other professional
fees. The increases in these categories are related to 2011 debt financing and the extensive work on SEC correspondence and Registration
Statements during fiscal year 2011. This increase is offset by the decrease in non-cash salary and wages expenses due valuations
of stock options granted in the current year.



As of the date of this report, except for
two, all employees have been laid off due to the lack of funding. In addition, all services and activities contained in the selling,
general and administrative expense category, except for expenses and services related to preserving the Corporate entity have been
suspended pending obtaining additional financing.



The table below details the major components
of selling, general and administrative expenses incurred:



|                                                                     |  | Year Ended December 31, |            |  | Difference |  
|-------------------------------------------------------------------- |  | ----------------------- | ---------- |  | ---------- | -
|                                                                     |  | 2011                    |            |  | 2010       |  
|                                                                     |  |                         |            |  |            |  
|Investor relations (including value of warrants/common stock shares) |  |                         | 3,586,170  |  |            |  
|Salary and wages (including value of options)                        |  |                         | 2,573,703  |  |            |  
|Accounting and other professional fees                               |  |                         | 2,579,308  |  |            |  
|Directors fees (including value of options)                          |  |                         | 366,139    |  |            |  
|Rent and office expenses                                             |  |                         | 197,339    |  |            |  
|Employee benefits                                                    |  |                         | 134,391    |  |            |  
|Travel and entertainment                                             |  |                         | 216,334    |  |            |  
|Insurance                                                            |  |                         | 84,990     |  |            |  
|Taxes and licenses                                                   |  |                         | 62,187     |  |            |  
|Patent expenses                                                      |  |                         | 112,462    |  |            |  
|Other                                                                |  |                         | 203,667    |  |            |  
|Total                                                                |  | $                       | 10,116,690 |  |            | $





Page 42 of 132







| | * | Percentage difference is over 100%
| | - | ----------------------------------



Impairments



Until September 2009, the Company was focused
on the production and distribution of pharmaceutical products through Jade Pharmaceuticals Inc. (“JPI”) our deconsolidated
subsidiary located in the People’s Republic of China.



In 2009, the Company refocused its business
on the development, manufacture and marketing of advanced, pioneering medical diagnostic products, including Onko-Sure®, a
proprietary In-Vitro Diagnostic (“IVD”) Cancer Test.



Due to several factors including deterioration
in its relationship with local management of JPI, the Company relinquished control over JPI and converted its interest in JPI to
that of an investment to be accounted for under the cost method, effective September 29, 2009. Accordingly, since September 29,
2009, the accounts and operations of JPI have been deconsolidated from our condensed consolidated financial statements. In connection
with the deconsolidation of JPI, effective September 29, 2009, we reclassified JPI as a business investment, rather than as a consolidated
operating subsidiary. Based on an evaluation performed by a third party valuation firm using Radient’s management’s
assessment of the current and projected operations of JPI as of December 31, 2010, we determined that our investment in JPI was
impaired. In consideration of the significant problems that management has had in obtaining the cooperation of JPI on a variety
of matters, the Company deemed that there was substantial uncertainty as to whether any amounts from their investment in JPI would
be realized. Accordingly, the Company decided to impair its investment to zero, as of December 31, 2010.



Other Income (Expense)



The increase of approximately $4.6
million in total other expenses, net is primarily due to approximately $41.8 million increase in loss on extinguishment of
debt as a result of the November 2011 exchange transaction that included the valuation of derivative liabilities and
accelerated amortization of debt discounts, $18.1 million increase in interest expense due to the interest penalties,
triggering events, issuance of debt instruments and warrants with derivative liabilities and amortization of the related debt
discounts and debt issuance costs, approximately $11 million loss on legal settlement, loss of approximately $840,000 in
guarantee, offset by the approximately $46.6 million net gain on change in fair value of derivative liabilities for the year
ended December 31, 2011.



Interest Expense



Interest expense for the years ended December
31, 2011 and 2010 was $56,562,089 and $38,485,599, respectively.



Interest expense increased due to the issuance
of convertible debt instruments with warrants treated as derivative liabilities, penalties related to trigger events and defaults
on convertible debt, and the amortization of the related debt discounts and debt issuance costs during the year ended December
31, 2011.



Interest expense is primarily comprised
of (i) $13,864,498 in excess fair value of the debt discount, recorded at origination, for the January 2011 Financing, July and
November Exchanged Notes for the derivatives associated with the conversion feature and warrants, (ii) $740,206 in accrued interest
and penalties added to derivatives, (iii) $24,151,821 of amortization of debt discounts and debt issuance costs on convertible
debt balances, (iv) $485,246 in incremental costs of re-pricing warrants in connection with the exchange of the Senior Notes into
convertible debt, (v) $15,551,761 in registration and default penalties and late fees added to the principal for the January 2011
Financing, (vi) $923,674 of interest expense on the outstanding principal balance and (vii) $718,320 cost of True Up shares issued
for Alpha and Whalehaven. (see the following table).



Page 43 of 132







|                                                  |  |  |     |  | Fair Value of Derivatives in Excess of Debt Discounts |   |            | Penalties Added To Principal |  |   | Interest and Penalties Added to Derivatives |  |  | Amortization of Debt Issuance Cost |         |  | Amortization of Debt Discount |   |           | Other |  |   | Total      | 
|------------------------------------------------- |  |  | --- |  | ----------------------------------------------------- | - | ---------- | ---------------------------- |  | - | ------------------------------------------- |  |  | ---------------------------------- | ------- |  | ----------------------------- | - | --------- | ----- |  | - | ---------- | 
|                                                  |  |  |     |  | [1]                                                   |   |            | [6]                          |  |   | [7]                                         |  |  | [8]                                |         |  | [8]                           |   |           |       |  |   |            | 
|Convertible Debt:                                 |  |  |     |  |                                                       |   |            |                              |  |   |                                             |  |  |                                    |         |  |                               |   |           |       |  |   |            | 
|1st Closing                                       |  |  |     |  |                                                       | $ | -          |                              |  | $ | -                                           |  |  | $                                  | 1,090   |  |                               | $ | -         |       |  | $ | -          | 
|2nd Closing                                       |  |  |     |  |                                                       |   |            |                              |  |   | 32,934                                      |  |  |                                    | 42,165  |  |                               |   | 112,613   |       |  |   | 1,466,391  | 
|3rd Closing                                       |  |  |     |  |                                                       |   | -          |                              |  |   | 219,446                                     |  |  |                                    | 41,485  |  |                               |   | 42,006    |       |  |   | 749,429    | 
|4th Closing                                       |  |  |     |  |                                                       |   | -          |                              |  |   | -                                           |  |  |                                    | 4,214   |  |                               |   | 16,207    |       |  |   | 199,830    | 
|2011 Notes & Exchanges                            |  |  |     |  |                                                       |   | 13,864,498 |                              |  |   | -                                           |  |  |                                    | 26,118  |  |                               |   | 1,066,195 |       |  |   | 20,499,150 | 
|2011 PS & Exchanges                               |  |  |     |  |                                                       |   | -          |                              |  |   | -                                           |  |  |                                    | 24,868  |  |                               |   | -         |       |  |   | -          | 
|Promissory Notes (A&W)                            |  |  |     |  |                                                       |   | -          |                              |  |   | 234,553                                     |  |  |                                    | 113,333 |  |                               |   | -         |       |  |   | -          | 
|Incremental cost of re-pricing of warrants        |  |  | [2] |  |                                                       |   | -          |                              |  |   | -                                           |  |  |                                    | -       |  |                               |   | -         |       |  |   | -          | 
|Registration, default, and late payment penalties |  |  | [3] |  |                                                       |   | -          |                              |  |   | 15,551,761                                  |  |  |                                    | -       |  |                               |   | -         |       |  |   | -          | 
|Registration penalties paid in cash               |  |  | [3] |  |                                                       |   | -          |                              |  |   |                                             |  |  |                                    | -       |  |                               |   | -         |       |  |   | -          | 
|Interest on debt                                  |  |  | [4] |  |                                                       |   | -          |                              |  |   | -                                           |  |  |                                    | -       |  |                               |   | -         |       |  |   | -          | 
|A&W True Up shares                                |  |  | [5] |  |                                                       |   | -          |                              |  |   | -                                           |  |  |                                    | -       |  |                               |   | -         |       |  |   | -          | 
|Total Interest expense                            |  |  |     |  |                                                       | $ | 13,864,498 |                              |  | $ | 16,038,694                                  |  |  | $                                  | 253,273 |  |                               | $ | 1,237,021 |       |  | $ | 22,914,800 | 



[1] This amount represents the excess fair value of the derivative
liability associated with the embedded conversion feature and warrants beyond the full debt discount taken (see Note 8 of the accompanying
consolidated financial statements).



[2] This amount represents the incremental costs associated
with the re-pricing of warrants issued in connection with the Senior Notes exchanged for convertible debt in January 2011.



[3] This amount represents registration penalties of $253,125
due to the registration of the shares underlying the January 2011 Notes not being declared effective as of March 31, 2011, late
payment penalties of $326,425, and default penalties of $15,098,774 for the January 2011 Financing (see Note 8 of the accompanying
consolidated financial statements).



[4] This amount represents the interest portion of the debt
based on the respective interest rates as noted, during the year ended December 31, 2011 (see Note 8 of the accompanying consolidated
financial statements).



[5] This amount represents the cost of shares issued for True
Up to Alpha and Whalehaven (see Note 8 of the accompanying consolidated financial statements).



[6] This represents penalties added to certain note holders
in regards to their forbearance agreement (see Note 8 of the accompanying consolidated financial statements).



[7] This represents the fair value of the derivative liability
associated with the interest and penalties added to the notes (see Note 8 of the accompanying consolidated financial statements).



[8] Total amortization of debt discount and debt issuance costs
for the year ended December 31, 2011 was $24,151,821.



Page 44 of 132









2010 Interest Expense:





|                                                        |     | [1]                                                                |            | [2],[4]                               |   | [3]                                                 |  |                                              |           |                                    |           |           
|------------------------------------------------------- | --- | ------------------------------------------------------------------ | ---------- | ------------------------------------- | - | --------------------------------------------------- |  | -------------------------------------------- | --------- | ---------------------------------- | --------- | ----------
|                                                        |     | Fair Value of
    Derivatives in 
    Excess of Debt
    Discounts |            | Penalties 
    Added To
    Principal |   | Interest and
    Penalties added
    to Derivatives |  | Amortization of 
    Debt Issuance 
    Cost |           | Amortization of 
    Debt Discount |           | Total     
|                                                        |     | [7]                                                                |            |                                       |   | [7]                                                 |  | [8]                                          |           | [8]                                |           |           
|Senior Notes:                                           |     |                                                                    |            |                                       |   |                                                     |  |                                              |           |                                    |           |           
|December 2008                                           |     | $                                                                  | -          |                                       | $ | -                                                   |  | $                                            | -         |                                    | $         | 169,947   
|January 2009                                            |     | -                                                                  |            | -                                     |   | -                                                   |  | 119,279                                      |           | 327,808                            |           | 447,087   
|May 2009                                                |     | -                                                                  |            | -                                     |   | -                                                   |  | 348,276                                      |           | 782,043                            |           | 1,130,319 
|June 2009                                               |     | -                                                                  |            | -                                     |   | -                                                   |  | 128,386                                      |           | 273,366                            |           | 401,752   
|Other                                                   |     | -                                                                  |            | 187                                   |   | -                                                   |  | 77,568                                       |           | 140,361                            |           | 218,116   
|                                                        |     |                                                                    |            |                                       |   |                                                     |  |                                              |           |                                    |           |           
|Convertible Debt:                                       |     |                                                                    |            |                                       |   |                                                     |  |                                              |           |                                    |           |           
|September 2008                                          |     | -                                                                  |            | 113,269                               |   | -                                                   |  | 410,454                                      |           | 1,741,910                          |           | 2,265,633 
|St. George                                              |     | -                                                                  |            | 50,000                                |   | 12,597                                              |  | 35,000                                       |           | 393,681                            |           | 491,278   
|1st Closing                                             |     | -                                                                  |            | 861,817                               |   | 325,727                                             |  | 112,000                                      |           | 651,165                            |           | 1,950,709 
|2nd Closing                                             |     | 3,968,028                                                          |            | 3,953,316                             |   | 1,240,359                                           |  | 315,221                                      |           | 3,811,792                          |           | 13,288,716
|3rd Closing                                             |     | 7,414,307                                                          |            | 2,748,333                             |   | 962,113                                             |  | 227,189                                      |           | 2,571,654                          |           | 13,923,596
|4th Closing                                             |     | 522,909                                                            |            | 480,108                               |   | 141,780                                             |  | 39,331                                       |           | 485,341                            |           | 1,669,469 
|                                                        |     |                                                                    |            |                                       |   |                                                     |  |                                              |           |                                    |           |           
|Incremental Cost of Shares and Warrants                 | [5] |                                                                    |            |                                       |   |                                                     |  |                                              |           |                                    | 81,780   
|Interest on Debt (excluding amounts added to principal) | [6] |                                                                    |            |                                       |   |                                                     |  |                                              |           |                                    | 2,129,019
|Total Interest expense                                  |     | $                                                                  | 11,905,244 |                                       | $ | 8,207,030                                           |  | $                                            | 2,682,576 |                                    | $         | 1,982,651 



|[1] |  | This amount represents the excess fair value of the debt discount related to the derivative liability
    associated with the embedded conversion feature and warrants (see Note 8 of the accompanying consolidated financial statements).                                                                
|--- |  | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|    |  |                                                                                                                                                                                                                                                                                                           
|[2] |  | This amount represents additional penalty interest and/or accrued interest added directly to the outstanding prinicipal
    of the convertible debt for trigger events and penalties added related to the forbearance agreement (see Note 8 of the accompanying
    consolidated financial statements).   
|    |  |                                                                                                                                                                                                                                                                                                           
|[3] |  | This amount represents additional interest recognized for the increase in principal balance associated with the embedded
    conversion feature of the First, Second, Third, and Fourth Closings as a result of the Trigger Events (see Note 8 of the accompanying
    consolidated financial statements).
|    |  |                                                                                                                                                                                                                                                                                                           
|[4] |  | This amount includes $410,000 of additional penalty recognized for the default related to the registration rights agreements
    as a result of not being declared effective related to the First, Second, Third, and Fourth Closings in 2010.                                                            
|    |  |                                                                                                                                                                                                                                                                                                           
|[5] |  | This amount represents the incremental costs associated with the additional shares and warrants issued in connection with
    the 2008 convertible debt that occurred during Q2 of 2010.                                                                                                                  
|    |  |                                                                                                                                                                                                                                                                                                           
|[6] |  | This amount represents the interest portion of the debt based on the respective interest rates as noted in Note 8, during
    the year ended December 31, 2010.                                                                                                                                           



|Sum of [7] |  | 14,587,820 |  | Total interest expense related to fair value of derivative instruments granted.
|---------- |  | ---------- |  | -------------------------------------------------------------------------------
|           |  |            |  |                                                                                
|Sum of [8] |  | 13,479,950 |  | Total amortization of debt discount and debt issuance costs.                   



Page 45 of 132







Loss from operations



For the year ended December 31, 2011 the
Company’s loss from operations was $86,187,269 or ($6.83) per share compared to the year ended December 31, 2010 when the
Company’s loss from operations was $85,711,853 or ($72.08) per share.



Liquidity and Capital Resources



For the year ended December 31, 2011,
the Company’s cash increased by $143,276 to $196,657, compared to a net increase in cash of $41,236 to $53,381 for the same
period in 2010.



Historically, our operations have not
been a source of liquidity. At December 31, 2011, we had a significant amount of relatively short term indebtedness that was in
default or past due and we may be unable to satisfy our obligations to pay interest and principal thereon. As of December 31,
2011, we had the following approximate amounts of outstanding short term indebtedness:



| | (i) | Accrued interest of approximately $606,224;
| | --- | -------------------------------------------



| | (ii) | Approximately $46,000 in unsecured convertible notes bearing default interest
    at 10% per annum increased to 18% per annum due to failure to pay the Notes by September 29, 2011. (See Note 8 of the accompanying
    consolidated financial statements.)
| | ---- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (iii) | Approximately $8.1 million in legal settlement promissory notes, bearing interest
    at 8% per annum.  We are obligated to retire the Notes in  monthly installments, commencing January 31, 2012, by
    payment in cash or (at our sole option) by delivery of shares of our common stock in an amount equal to 6.25% of the initial
    principal amount of each Note, plus accrued interest.
| | ----- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (iv) | Approximately $4.5 million in Series B and C convertible Preferred Stock, accruing
    dividends at 4% per annum
| | ---- | ----------------------------------------------------------------------------------------------------------------



| | (iv) | Approximately $4.9 million in senior unsecured promissory notes bearing interest
    at 18% interest, payable quarterly in cash, which are due between December 2011 and May 2011.
| | ---- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Operating activities



Net cash in used in operating activities
in the year ended December 31, 2011, was $5,654,228 compared with cash used in operating activities of continuing operations of
$7,112,307 for the same period in 2010.



The primary use of cash in operations
during the year ended December 31, 2011 and 2010 was the net loss of approximately $86.2 million and $85.7 million, respectively.
The effect of the net loss during the year ended December 31, 2011 was partially offset by significant non-cash activity such
as:



| | (i)  | approximately $24.2 million for the amortization of
        debt issuance costs and debt discounts,             
| | ---- | ----------------------------------------------------------------------------------------------------------------
| | (ii) | approximately $1.1 million for the fair value of options
        granted to employees and directors for service,

| | (iii) | approximately $3.6 million representing the fair market
        value of common stock, warrants and options expensed for services,
| | ----- | ----------------------------------------------------------------------------------------------------------------------------------
| | (iv)  | approximately $16.0 million related to additional principal
        added for triggering events, and forbearance agreements,      

| | (v) | approximately $11.0 million representing additional
        principal added for settlement ,
| | --- | --------------------------------------------------------------------------------------------

| | (vi) | approximately $45 million representing loss on extinguishment
        of debt, and
| | ---- | ----------------------------------------------------------------------------------

| | (vii)  | approximately $14.1 million representing interest expense
        related to fair value of derivative instruments granted, and
| | ------ | ------------------------------------------------------------------------------------------------------------------------------
| | (viii) | approximately $37.2 million representing the change in fair value of the derivative liabilities.                              



Page 46 of 132







Due to the lack of funds, we suspended most operating activities
except for those critical to preserving the Corporate entity.



Investing activities



We used $30,459 in investing activities
from operations in the year ended December 31, 2011 compared with $27,990 for the same period in 2010.



Financing activities



Net cash provided by financing activities
from operations was $5,827,963 for the year ended December 31, 2011, primarily consisting of the net proceeds of $6,820,000 from
the issuance of convertible debt, net proceeds of $433,780 from exercise of Series B warrants for Series C Preferred Stock, net
proceeds of $159,763 from JPI guarantee and net proceeds of $101,920 from the exercise of warrants into common stock. Such increase
was offset by $1,687,500 of principal payments related to the 2011 financing. Net cash provided by financing activities was $7,181,533
for the year ended December 31, 2010, primarily consisting of the net proceeds of $6,308,000 from the issuance of convertible
debt, and net proceeds of $873,533 from the exercise of warrants into common stock.



Future Capital Needs



If funding is obtained, we expect to incur
additional capital expenditures in 2012 in the form of re-starting operations by retaining qualified individuals for manufacturing,
accounting and support staff. Depending on the extent of funding, we intend to re-start the project to further develop the Onko-Sure®
test kit and upgrading manufacturing lines in Tustin.



Going Concern



The consolidated financial statements
have been prepared assuming we will continue as a going concern, which contemplates, the realization of assets and satisfaction
of liabilities in the normal course of business. We incurred losses from continuing operations of $86,187,269 and $85,711,853
for the years ended December 31, 2011 and 2010, respectively, and had an accumulated deficit of $224,337,675 at December 31, 2011.
In addition, we used cash in operating activities of continuing operations of $5,654,228 and had a working capital deficit of
approximately $49.8 million. These factors raise substantial doubt about our ability to continue as a going concern.



Due to the lack of funding, as of April
17, 2012, all employees, except for two have been laid off. Former employees are retained on a consulting basis as needed. In
addition, except for activities and expenses related to preserving the Corporate entity, all activity has been suspended pending
obtaining additional funding. As a result, the Company’s monthly cash requirement has decreased to approximately$40,000
per month. This monthly cash requirement does not include any extraordinary items or expenditures, including cash payments for
debt penalties or recurring principal and interest payments, payments for clinical trials for our Onko-Sure® test kit, research
conducted through CLIA Laboratories or expenditures related to further development of the CIT technology, as no significant expenditures
are anticipated other than recurring legal fees related to outstanding legal proceedings. Based on our current cash position,
without additional financing we are notable to pay our all of our past obligations.



Management’s plans
include seeking financing, conversion of certain existing notes payable and related warrant obligations to preferred and
common stock, alliances or other partnership agreements with entities interested in our technologies, or other business
transactions that would generate sufficient resources to assure continuation of our operations and research and development
programs. To date, management has been unable to establish a definitive plan to locate funding and/or any partnership or
alliance to allow us to address our significant capital deficiencies.



There are significant risks and uncertainties
which could negatively affect our operations. These are principally related to (i) the ability to retain skilled workers to manufacture
kit and conduct research and development, (ii) ability to re-start operations, (iii) the absence of substantive distribution network
for our Onko-Sure® kits, (iv) the absence of any significant commitments or firm orders from our distributors, (v) existing
defaults and potential defaults in existing indebtedness, and (vi) failure to meet operational covenants in existing financing
agreements which would trigger additional defaults or penalties. Our limited sales to date for the Onko-Sure ® test kit and
the lack of distributors meeting their quarterly minimum purchase requirements make it impossible to identify any trends in our
business prospects.



Page 47 of 132







Our only sources of additional funds to
meet continuing operating expenses, fund additional research and development and fund additional working capital are through the
sale of securities, and/or debt instruments. We are actively seeking additional debt or equity financing, but no assurances can
be given that such financing will be obtained or what the terms thereof will be.



Item 7A. Quantitative and Qualitative Disclosures About
Market Risk



Not applicable.



Item 8. Financial Statements



Page 48 of 132







REPORT OF INDEPENDENT REGISTERED PUBLIC
ACCOUNTING FIRM



Board of Directors and Stockholders

Radient Pharmaceuticals Corporation



We have audited the accompanying consolidated
balance sheets of Radient Pharmaceuticals Corporation and subsidiaries (the “Company”) as of December 31, 2011 and
2010, and the related consolidated statements of operations, stockholders’ deficit, and cash flows for the years then ended.
These consolidated financial statements are the responsibility of the Company’s management. Our responsibility is to express
an opinion on these consolidated financial statements based on our audits.



We conducted our audits in accordance
with the standards of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and
perform the audits to obtain reasonable assurance about whether the consolidated financial statements are free of material misstatement.
The Company has determined that it is not required to have, nor were we engaged to perform, an audit of its internal control over
financial reporting. Our audits included consideration of internal control over financial reporting as a basis for designing audit
procedures that are appropriate in the circumstances, but not for the purpose of expressing an opinion on the effectiveness of
the Company’s internal control over financial reporting. Accordingly, we express no such opinion. An audit also includes
examining, on a test basis, evidence supporting the amounts and disclosures in the consolidated financial statements. An audit
also includes assessing the accounting principles used and significant estimates made by management, as well as evaluating the
overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion.



In our opinion, the consolidated financial
statements referred to above present fairly, in all material respects, the consolidated financial position of Radient Pharmaceuticals
Corporation and subsidiaries as of December 31, 2011 and 2010, and the results of their operations and their cash flows for the
years then ended in conformity with accounting principles generally accepted in the United States of America.



As described in Note 16 to the consolidated
financial statements, on February 22, 2012, the Company was delisted from the Pink OTC Markets, which constituted an event of default
under certain of the Company’s outstanding notes.



The accompanying consolidated financial
statements have been prepared assuming the Company will continue as a going concern. As more fully described in Note 1 to the
consolidated financial statements, the Company has incurred significant operating losses, had negative cash flows from operations
in 2011 and 2010, and has a working capital deficit of approximately $49.8 million at December 31, 2011. These items raise substantial
doubt about the Company’s ability to continue as a going concern. Management’s plans in regard to these matters are
also described in Note 1. The consolidated financial statements do not include any adjustments relating to the recoverability
and classification of asset carrying amounts or the amount and classification of liabilities that might result should the Company
be unable to continue as a going concern.



|/s/ KMJ Corbin & Company LLP | 
|---------------------------- | 
|KMJ Corbin & Company LLP     | 
|Costa Mesa, California       | 
|June 29, 2012                | 



Page 49 of 132







RADIENT PHARMACUETICALS CORPORATION

CONSOLIDATED BALANCE SHEETS

|                                                                                                                           |  | December 31, |              |   | December 31, |  
|-------------------------------------------------------------------------------------------------------------------------- |  | ------------ | ------------ | - | ------------ | -
|                                                                                                                           |  | 2011         |              |   | 2010         |  
|                                                                                                                           |  |              |              |   |              |  
|ASSETS                                                                                                                     |  |              |              |   |              |  
|Current assets:                                                                                                            |  |              |              |   |              |  
|Cash                                                                                                                       |  | $            | 196,657      |   |              | $
|Accounts receivable                                                                                                        |  |              | 6,835        |   |              |  
|Inventories                                                                                                                |  |              | 89,787       |   |              |  
|Prepaid expenses and other current assets                                                                                  |  |              | 141,888      |   |              |  
|Prepaid consulting                                                                                                         |  |              | 675,288      |   |              |  
|Debt issuance cost                                                                                                         |  |              | -            |   |              |  
|Total current assets                                                                                                       |  |              | 1,110,455    |   |              |  
|Property and equipment, net                                                                                                |  |              | 65,685       |   |              |  
|Other assets                                                                                                               |  |              | -            |   |              |  
|Total assets                                                                                                               |  | $            | 1,176,140    |   |              | $
|LIABILITIES AND STOCKHOLDERS’ DEFICIT                                                                                      |  |              |              |   |              |  
|Current liabilities:                                                                                                       |  |              |              |   |              |  
|Accounts payable and accrued expenses                                                                                      |  | $            | 895,920      |   |              | $
|Accrued salaries and wages                                                                                                 |  |              | 231,991      |   |              |  
|Accrued share-based compensation                                                                                           |  |              | 1,816,965    |   |              |  
|Accrued interest expense                                                                                                   |  |              | 606,224      |   |              |  
|Derivative liabilities                                                                                                     |  |              | 38,366,767   |   |              |  
|Deferred revenue                                                                                                           |  |              | -            |   |              |  
|Convertible notes and preferred stock, net of discounts of $8,544,200 and $2,415,647, respectively                         |  |              | 8,948,131    |   |              |  
|Notes payable                                                                                                              |  |              | -            |   |              |  
|Total current liabilities                                                                                                  |  |              | 50,865,998   |   |              |  
|Commitments and contingencies                                                                                              |  |              | -            |   |              |  
|Stockholders’ deficit:                                                                                                     |  |              |              |   |              |  
|Preferred stock, $0.001 par value; 25,000,000 shares authorized;                                                           |  |              |              |   |              |  
|Series A: 670,100 issued and  0 outstanding at December 31, 2011 and 2010, respectively                                    |  |              | -            |   |              |  
|Series B: 402,441 issued and 395,602 and 0 outstanding at December 31, 2011 and 2010, respectively                         |  |              | -            |   |              |  
|Series C: 50,000 and 0 issued and outstanding at December 31, 2011 and 2010, respectively                                  |  |              | -            |   |              |  
|Common stock, $0.001 par value; 5,000,000,000 and 8,000,000 shares authorized at December 31, 2011 and 2010, respectively; |  |              |              |   |              |  
|42,178,095 and 1,536,087 shares issued at December 31, 2011 and  2010, respectively;                                       |  |              |              |   |              |  
|42,178,095 and 1,500,087 shares outstanding at December 31, 2011 and 2010, respectively                                    |  |              | 42,178       |   |              |  
|Additional paid-in capital                                                                                                 |  |              | 174,605,639  |   |              |  
|Accumulated deficit                                                                                                        |  |              | (224,337,675 | ) |              |  
|Total stockholders’ deficit                                                                                                |  |              | (49,689,858  | ) |              |  
|Total liabilities and stockholders’ deficit                                                                                |  | $            | 1,176,140    |   |              | $



See accompanying notes to consolidated
financial statements.



Page 50 of 132







RADIENT PHARMACUETICALS CORPORATION

CONSOLIDATED STATEMENTS OF OPERATIONS



|                                                                 |  | Year Ended December 31, |            
|---------------------------------------------------------------- |  | ----------------------- | -----------
|                                                                 |  | 2011                    |            
|Net revenues                                                     |  | $                       | 313,559    
|Cost of sales                                                    |  |                         | 51,776     
|Gross profit                                                     |  |                         | 261,783    
|Operating expenses:                                              |  |                         |            
|Research and development                                         |  |                         | 115,476    
|Selling, general and administrative                              |  |                         | 10,116,690 
|Impairment of receivable from JPI                                |  |                         | -          
|Impairment of intangible assets                                  |  |                         | -          
|Total operating expenses                                         |  |                         | 10,232,166 
|Loss from operations                                             |  |                         | (9,970,383 
|Other income (expense):                                          |  |                         |            
|Interest expense                                                 |  |                         | (56,562,089
|Other expense, net                                               |  |                         | (319       
|Change in fair value of derivative liabilities                   |  |                         | 37,204,639 
|Impairment on investment in JPI                                  |  |                         | -          
|Loss on extinguishment of debt                                   |  |                         | (45,031,825
|Loss on legal settlement                                         |  |                         | (10,987,055
|Loss on guarantee                                                |  |                         | (840,237   
|Total other expense, net                                         |  |                         | (76,216,886
|Loss before provision for income taxes                           |  |                         | (86,187,269
|Provision for income taxes                                       |  |                         | -          
|Net loss                                                         |  | $                       | (86,187,269
|Basic and diluted loss per common share:                         |  |                         |            
|Net loss                                                         |  | $                       | (6.83      
|Weighted average common shares outstanding basic and
    diluted |  |                         | 12,612,759 



See accompanying notes to consolidated
financial statements.



Page 51 of 132







RADIENT PHARMACUETICALS CORPORATION

CONSOLIDATED STATEMENTS OF STOCKHOLDERS’
DEFICIT

For The Years Ended December 31, 2011
and 2010



|                                                                                                                                      |  | Common 
    Stock |            |  | Preferred
    Stock |   |        | Additional
    Paid-in |  |  | Accumulated |  |  | Total
    Stockholders’ |  
|------------------------------------------------------------------------------------------------------------------------------------- |  | ----------------- | ---------- |  | ------------------- | - | ------ | ---------------------- |  |  | ----------- |  |  | ----------------------- | -
|                                                                                                                                      |  | Shares            |            |  | Amount              |   |        | Shares                 |  |  | Amount      |  |  | Capital                 |  
|                                                                                                                                      |  |                   |            |  |                     |   |        |                        |  |  |             |  |  |                         |  
|Balance, January 1, 2010                                                                                                              |  |                   | 890,618    |  |                     | $ | 891    |                        |  |  | -           |  |  | $                       | -
|                                                                                                                                      |  |                   | -          |  |                     |   |        |                        |  |  |             |  |  |                         |  
|Common stock issued for consulting services                                                                                           |  |                   | 195,714    |  |                     |   | 196    |                        |  |  | -           |  |  |                         | -
|Share-based employee and director compensation                                                                                        |  |                   | -          |  |                     |   | -      |                        |  |  | -           |  |  |                         | -
|Common stock issued for settlement of accounts
    payable                                                                            |  |                   | 6,428      |  |                     |   | 6      |                        |  |  | -           |  |  |                         | -
|Estimated fair value of warrants and options
    issued to third parties for services                                                 |  |                   | -          |  |                     |   | -      |                        |  |  | -           |  |  |                         | -
|Common stock issued for the voluntary conversion
    of debt and accrued  interest                                                    |  |                   | 309,173    |  |                     |   | 309    |                        |  |  | -           |  |  |                         | -
|Common stock issued for the exercise of warrants                                                                                      |  |                   | 98,154     |  |                     |   | 98     |                        |  |  | -           |  |  |                         | -
|Reclassification of derivative liability due
    to conversion of debt and exercise of warrants                                       |  |                   | -          |  |                     |   | -      |                        |  |  | -           |  |  |                         | -
|Beneficial conversion feature of debt                                                                                                 |  |                   | -          |  |                     |   | -      |                        |  |  | -           |  |  |                         | -
|Net loss                                                                                                                              |  |                   | -          |  |                     |   | -      |                        |  |  | -           |  |  |                         | -
|Balance, December 31, 2010                                                                                                            |  |                   | 1,500,087  |  |                     | $ | 1,500  |                        |  |  | -           |  |  | $                       | -
|                                                                                                                                      |  |                   |            |  |                     |   |        |                        |  |  |             |  |  |                         |  
|                                                                                                                                      |  |                   |            |  |                     |   |        |                        |  |  |             |  |  |                         |  
|Common stock issued for consulting services                                                                                           |  |                   | 2,905,714  |  |                     |   | 2,906  |                        |  |  | -           |  |  |                         | -
|Share-based compensation-  employees, directors
    and legal counsel                                                                 |  |                   | -          |  |                     |   | -      |                        |  |  | -           |  |  |                         | -
|Common stock issued to directors for services                                                                                         |  |                   | 4,800      |  |                     |   | 5      |                        |  |  | -           |  |  |                         | -
|Common stock issued for legal settlement                                                                                              |  |                   | 20,000     |  |                     |   | 20     |                        |  |  | -           |  |  |                         | -
|Common stock issued for conversion of debt,
    preferred stock and accrued interest                                                  |  |                   | 26,503,634 |  |                     |   | 26,504 |                        |  |  | -           |  |  |                         | -
|Common stock issued for the exercise of warrants,
    net of commission of $10,080                                                    |  |                   | 16,000     |  |                     |   | 16     |                        |  |  | -           |  |  |                         | -
|Common stock issued for the cashless exercise
    of warrants                                                                         |  |                   | 965,527    |  |                     |   | 965    |                        |  |  | -           |  |  |                         | -
|Fair value of true-up shares issued to Alpha
    & Whalehaven                                                                         |  |                   | 5,916,000  |  |                     |   | 5,916  |                        |  |  | -           |  |  |                         | -
|Legal fees related to Series B warrants exercised
    for Series C Preferred stock                                                    |  |                   | -          |  |                     |   | -      |                        |  |  | -           |  |  |                         | -
|Common stock issued for JPI guarantee                                                                                                 |  |                   | 4,346,333  |  |                     |   | 4,346  |                        |  |  | -           |  |  |                         | -
|Reclassification of derivative liabilities
    due to conversion of preferred stock, debt, accrued interest, and exercise of warrants |  |                   |            |  |                     |   | -      |                        |  |  | -           |  |  |                         | -
|Beneficial conversion feature                                                                                                         |  |                   | -          |  |                     |   | -      |                        |  |  | -           |  |  |                         | -
|Repricing of warrants                                                                                                                 |  |                   | -          |  |                     |   | -      |                        |  |  | -           |  |  |                         | -
|Reclassification of warrants and beneficial
    conversion feature not previously classified as derivatives                           |  |                   | -          |  |                     |   | -      |                        |  |  | -           |  |  |                         | -
|Net loss                                                                                                                              |  |                   |            |  |                     |   | -      |                        |  |  | -           |  |  |                         | -
|Balance, December 31, 2011                                                                                                            |  |                   | 42,178,095 |  |                     | $ | 42,178 |                        |  |  | -           |  |  | $                       | -



See accompanying notes to consolidated
financial statements.



Page 52 of 132







RADIENT PHARMACEUTICALS CORPORATION

CONSOLIDATED STATEMENTS OF CASH FLOWS



|                                                                                                         |  | Year Ended December 31, |            
|-------------------------------------------------------------------------------------------------------- |  | ----------------------- | -----------
|                                                                                                         |  | 2011                    |            
|Cash flows from operating activities:                                                                    |  |                         |            
|Net loss                                                                                                 |  | $                       | (86,187,269
|                                                                                                         |  |                         |            
|Adjustments to reconcile net loss to net cash used in operating activities:                              |  |                         |            
|Depreciation and amortization                                                                            |  |                         | 40,736     
|Amortization of debt discount and accretion of debt issuance costs                                       |  |                         | 24,151,821 
|Impairment of receivable from JPI                                                                        |  |                         | -          
|Impairment of intangible assets                                                                          |  |                         | -          
|Impairment on investment in JPI                                                                          |  |                         | -          
|Interest expense related to fair value of derivative instruments granted                                 |  |                         | 14,117,771 
|Interest expense related to additional principal added for penalties and triggering events               |  |                         | 16,038,694 
|Interest expense related to incremental value of shares and warrants issued to note holders              |  |                         | 485,246    
|Interest expense related to true up shares for A&W                                                       |  |                         | 718,320    
|Loss on JPI guarantee                                                                                    |  |                         | 840,237    
|Loss on debt extinguishment                                                                              |  |                         | 45,031,825 
|Additional principal added for Legal settlement                                                          |  |                         | 10,987,055 
|Fair value of common stock shares issued to directors services                                           |  |                         | 31,180     
|Share-based compensation related to options granted to employees, directors and consultants for services |  |                         | 1,102,190  
|Share-based compensation related to common stock and warrants expensed for services                      |  |                         | 3,625,248  
|Change in fair value of derivative liabilities                                                           |  |                         | (37,204,639
|Changes in operating assets and liabilities:                                                             |  |                         |            
|Accounts receivable                                                                                      |  |                         | (4,232     
|Inventories                                                                                              |  |                         | (6,883     
|Prepaid expenses and other assets                                                                        |  |                         | (1,602     
|Accounts payable, accrued expenses, accrued salaries and wages                                           |  |                         | 604,824    
|Deferred revenue                                                                                         |  |                         | (24,750    
|Net cash used in operating activities                                                                    |  |                         | (5,654,228 
|                                                                                                         |  |                         |            
|Cash flows from investing activities:                                                                    |  |                         |            
|Purchase of property and equipment                                                                       |  |                         | (30,459    
|Net cash used in investing activities                                                                    |  |                         | (30,459    
|                                                                                                         |  |                         |            
|Cash flows from financing activities:                                                                    |  |                         |            
|Payments on convertible debt, 2011 financing                                                             |  |                         | (1,687,500 
|Proceeds from issuance of convertible debt, net of cash offering costs                                   |  |                         | 6,820,000  
|Proceeds from JPI guarantee                                                                              |  |                         | 159,763    
|Proceeds from exercise of Series B warrants for Series C Preferred stock                                 |  |                         | 433,780    
|Proceeds from the exercise of warrants and options, net of commission and expenses                       |  |                         | 101,920    
|Net cash provided by financing activities                                                                |  |                         | 5,827,963  
|                                                                                                         |  |                         |            
|Net change in cash                                                                                       |  |                         | 143,276    
|Cash, beginning of year                                                                                  |  |                         | 53,381     
|                                                                                                         |  |                         |            
|Cash, end of year                                                                                        |  | $                       | 196,657    



See Note 1 to consolidated financial statements
for supplemental cash flow information and non-cash investing and financing activities.

See accompanying notes to consolidated
financial statements



Page 53 of 132







NOTE 1 — ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING
POLICIES



Nature of Business



Since inception, Radient Pharmaceuticals
Corporation (the “Company”, “Radient”, “we”, “our”, or “us”), a Delaware
Corporation has been engaged in the research, development, manufacturing, sale and marketing of our Onko-Sure ® test kit,
which is a proprietary in-vitro diagnostic (or IVD) cancer test. We market our Onko-Sure®test kits in the United States,
Canada, Chile, Europe, India, Korea, Japan, Taiwan, Vietnam and other markets throughout the world. Our product is sold either
directly to Clinical Laboratory Improvement Amendments (“CLIA”) certified reference laboratories or to third party
distributors, who then resell to CLIA certified reference laboratories in the United States as well as clinical reference labs,
hospital laboratories and physician operated laboratories in the international market.



Our Onko-Sure®IVD test enables
physicians and their patients to detect and/or monitor the treatment/recurrence of solid tumors by measuring the accumulation
of specific breakdown products in the blood called Fibrin and Fibrinogen Degradation Products (FDP). Onko-Sure® is a simple,
non-invasive blood test designed to be used for the detection and/or monitoring of 19 different types of cancer including: lung,
breast, tongue, stomach, liver, colon, rectal, bladder, brain, hematological, prostate, ovarian, esophageal, cervical, uterine,
liver, trophoblastic, thyroid, malignant lymphoma, and pancreatic cancers. We believe that Onko-Sure® can be a valuable diagnostic
tool in the worldwide battle against cancer. Because the Onko-Sure® test kit is a non-invasive blood test, there are no side
effects of the administration of the test. As with other cancer diagnostic products, false positive and false negative test results
could pose a small risk to patient health if the physician is not vigilant in following up on the Onko-Sure® test kit results
with other clinically relevant diagnostic modalities. While the Onko-Sure®, like other blood biomarker tests, could be helpful
in cancer detection, the attending physician is required to use other testing methods to confirm the type of cancer.



Onko-Sure® is sold as a blood test
for cancer in Europe (CE Mark certified), India, Japan, Taiwan, Korea, Vietnam, and in Chile (research use). In the United States,
it is cleared by the Food and Drug Administration (FDA) for the monitoring of colorectal cancer treatment and recurrence, and
is approved in Canada (by Health Canada) for lung cancer detection and treatment/recurrence monitoring. We believe that Onko-Sure®
has the potential to be used as a general cancer screening test. We are involved with research conducted with CLIA laboratories
to expand on the clinical utility of Onko-Sure®.



We manufacture and distribute our cancer
test kits at our licensed manufacturing facility located at 2492 Walnut Avenue, Suite 100, in Tustin, California. We are a United
States Food and Drug Administration (“FDA”), “good manufacturing practices” compliant facility. We maintain
a current Device Manufacturing License issued by the State of California, Department of Health Services, Food and Drug Branch.



On September 25, 2009, we changed our
corporate name from “AMDL, Inc.” to Radient Pharmaceuticals Corporation.



Until September 2009, the Company was
focused on the production and distribution of pharmaceutical products through Jade Pharmaceuticals Inc. (“JPI”) our
subsidiary located in the People’s Republic of China. The Company recently refocused its business on the development, manufacture
and marketing of advanced, pioneering medical diagnostic products, including Onko-Sure®, a proprietary In-Vitro Diagnostic
(“IVD”) Cancer Test.



Due to several factors including deterioration
in its relationship with local management of JPI, the Company relinquished control over JPI and converted its interest in JPI
to that of an investment accounted for under the cost method, effective September 29, 2009. Accordingly, since September 29, 2009,
the accounts and operations of JPI have been deconsolidated from our consolidated financial statements.



In connection with the deconsolidation
of JPI, effective September 29, 2009, we reclassified JPI as a business investment, rather than as a consolidated operating subsidiary.
Based on an evaluation performed by a third party valuation firm using Radient’s management’s assessment of the current
and projected operations of JPI as of December 31, 2010, we determined that our investment in JPI was impaired. In consideration
of the significant problems that management has had in obtaining the cooperation of JPI on a variety of matters, the Company deemed
that there was substantial uncertainty as to whether any amounts from their investment in JPI would be realized.



Page 54 of 132







Accordingly, the Company decided to impair
its investment to zero, as of December 31, 2010. The Company will, however, pursue an action plan to recover a portion or all
of its investment.



During the third and fourth quarter of
2009, we repositioned certain business assets that we believe will enable us to monetize such assets through new partnerships,
separate potential reverse mergers or possible sales. These special assets include: (i) our 97.4% ownership in China-based pharmaceuticals
business, JPI; and (ii) our 100% ownership of a proprietary cancer vaccine therapy technology: Combined Immunogene Therapy (“CIT”).



In December 2010, we formed NuVax Therapeutics,
Inc. (“NuVax”), a wholly-owned subsidiary, to expand clinical trials in multiple international locations and in the
U.S., and the in-licensing of other novel cancer fighting technologies. All rights to our CIT technology will be transferred to
NuVax, currently our 100% wholly-owned subsidiary. All further development and commercialization of CIT and other to-be licensed
novel cancer fighting technologies will be made at NuVax.



We continue to have 100% ownership of
the Elleuxe brand of advanced skin care products with proprietary formulations; however, we currently intend to license or sell
off our Elleuxe brand of cosmetic products because our focus is on the development and marketing of our Onko-Sure® test kit
product.



The Company is actively engaged in the
research, development, manufacturing, sale and marketing of Onko-Sure®, a proprietary IVD Cancer Test in the United States,
Canada, China, Chile, Europe, India, Korea, Taiwan, Vietnam, Japan and other markets throughout the world. The Company manufactures
and distributes Onko-Sure® at the Company’s licensed manufacturing facility located at 2492 Walnut Avenue, Suite 100,
in Tustin, California. The Company is a United States Food and Drug Administration (“USFDA”) Good Manufacturing Practices
(“GMP”) approved manufacturing facility. The Company maintains a current Device Manufacturing License issued by the
State of California, Department of Health Services, Food and Drug Branch.



On November 4, 2011, the Company filed
a Certificate of Amendment of its Amended and Restated Certificate of Incorporation to increase its authorized common stock shares
to 5 billion and preferred stock shares to 25 million. In addition, the Company affected a reverse stock split of the Company’s
issued and outstanding shares of common stock at a ratio of 1:25 (the “Reverse Split”).  The Reverse Split
provides that each twenty-five (25) outstanding shares of the Corporation’s common stock, par value $0.001 per share, will
be exchanged and combined, automatically, without further action, into one (1) share of common stock. The Reverse Split was
declared effective on February 10, 2012 by FINRA and has been retroactively reflected in the Company’s December 31, 2011
Annual Report on Form 10-K.



As a result of our working capital
deficiencies, as of April 17, 2012, the Company laid off a substantial portion of our work force and are currently operating
on a minimal basis with only  two employees and three former employee consultants. The current focus of our operations is to
ensure that our existing Onko-Sure® customers and any future customers are able to place orders and receive kits on a
timely basis. We have an Onko-Sure® production continuity arrangement in place with one vendor. At the current time, the
Company believes that it does not require any additional staff to perform this limited manufacturing, quality control and
selling process.



The Company appointed a committee of three
independent directors to assess available options open to the Company to enable us to continue operations. Due to the
shortage of working capital, we were unable to pay premiums associated with our Directors and Officers insurance. As
a consequence, on June 25, 2012, we were informed by two members of our Board of Directors of their resignation. As a result,
we have only one independent Director serving on our Board at this time. Although our remaining
sales team continues to work towards completing pending and future sales of our Onko-Sure ® test kit, if these sales
are not completed and we do not otherwise raise additional funds in the immediate future, it is likely that we will be forced
to cease all operations and might seek protection from our creditors under the United States bankruptcy laws.



Impairment of Investment in and Receivable from JPI



Investment in JPI



Based on a valuation performed by a third-party
valuation firm using Radient’s management’s assessment of the current and projected operations of JPI as of December 31,
2010, and on other factors, we determined that our investment in JPI was impaired due to:



| | · | Reduced projected sales growth;
| | - | -------------------------------



| | · | Negative debt-free net cash flows from operations in 2009 and 2010, and reduced positive amounts projected
    for 2011 to 2015;
| | - | --------------------------------------------------------------------------------------------------------------------------------



Page 55 of 132







| | · | Negative earnings before interest, taxes, depreciation, and amortization (“EBITA”) in 2009
    and 2010, and reduced positive amounts projected for 2011 to 2015; and
| | - | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | Lack of products in manufacturing pipeline.
| | - | -------------------------------------------



The third-party valuation estimated the
value of the Company’s investment to be approximately $2,079,000 before further consideration on the likelihood of being
able to realize any amounts from the investment. In consideration of the significant problems that management has had in obtaining
the cooperation of JPI on a variety of matters, the Company deemed that there was substantial uncertainty as to whether any amounts
from their investment in JPI would be realized. Some of the significant problems that the Company has had concerning the cooperation
with JPI management included the following:



| | · | Continued inability to receive financial information from JPI in a timely manner;
| | - | ---------------------------------------------------------------------------------



| | · | Continued difficulty in preparing GAAP based financial statements;
| | - | ------------------------------------------------------------------



| | · | A merger partner has been identified; however, JPI was unable to complete the
    transaction prior to the expiration of the letter of intent. A bridge loan was secured for $1,000,000 to fund valuation, legal
    and accounting related to the merger; however, JPI management has not authorized these actions.
| | - | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Accordingly, the Company decided to impair
its investment to zero, and thereby recognized an impairment charge of $20,500,000 on the investment in the accompanying consolidated
statement of operations for the year ended December 31, 2010. The Company will, however, pursue an action plan to recover a portion
or all of its investment. For financial reporting purposes, the impairment is permanent, and the investment balance in JPI will
not be increased in the future if the circumstances change. However, if ultimately the Company realizes all or a portion of its
investment in JPI, the Company will recognize a gain when realized.



Going Concern



The consolidated financial statements
have been prepared assuming we will continue as a going concern, which contemplates, the realization of assets and satisfaction
of liabilities in the normal course of business. We incurred losses from continuing operations of $86,187,269 and $85,711,853
for the years ended December 31, 2011 and 2010, respectively, and had an accumulated deficit of $224,337,675 at December 31, 2011.
In addition, we used cash in operating activities of $5,654,228 and had a working capital deficit of approximately $49.8 million.
These factors raise substantial doubt about our ability to continue as a going concern.





Management’s plans include seeking
financing, conversion of certain existing notes payable and related warrant obligations to preferred and common stock, alliances
or other partnership agreements with entities interested in our technologies, or other business transactions that would generate
sufficient resources to assure continuation of our operations and research and development programs.



The committee of our three independent
directors continues to assess whether the Company has any other options to remain in business. Due to the
shortage of working capital, we were unable to pay premiums associated with our Directors and Officers insurance. As
a consequence, on June 25, 2012, we were informed by two members of our Board of Directors of their resignation. As a result,
we have only one independent Director serving on our Board at this time. Although our remaining sales team
continues to work towards completing pending and future sales of our Onko-Sure ® test kit, if these sales are not completed
and we do not otherwise raise additional funds in the immediate future, it is likely that we will be forced to cease all operations
and might seek protection from our creditors under the United States bankruptcy laws.



Page 56 of 132







There are significant risks and uncertainties
which could negatively affect our operations. These are principally related to (i) the absence of substantive distribution network
for our Onko-Sure® test kits, (ii) the absence of any significant commitments or firm orders from our distributors, (iii)
existing defaults and potential defaults in existing indebtedness, and (iv) failure to meet operational covenants in existing
financing agreements which would trigger additional defaults or penalties. Our limited sales to date for the Onko-Sure ® test
kit and the lack of distributors meeting their quarterly minimum purchase requirements make it impossible to identify any trends
in our business prospects.



Our only sources of additional funds to
meet continuing operating expenses, fund additional research and development and fund additional working capital is through a
merger or a business combination. . Due to the lack of funding, we suspended all activities except for activities necessary to
continue the corporate entity and process Onko-Sure® test kits as orders are received.



Principles of Consolidation



The accompanying consolidated financial
statements include the accounts of Radient and Nuvax. All intercompany accounts and transactions have been eliminated. NuVax had
no operations for the year ended December 31, 2011.



Use of Estimates



The preparation of financial statements
in conformity with Generally Accepted Accounting Principles in the United States of America (“GAAP”) requires management
to make certain estimates and assumptions that affect the reported amounts of assets and liabilities at the date of the financial
statements and the reported amounts of revenues and expenses during the reporting period. Significant estimates made by management
are, realizability of accounts receivable and inventories, recoverability of long-lived assets,  valuation of derivative liabilities, and valuation of  stock options, warrants and deferred tax assets.
Actual results could differ from those estimates.



Revenue Recognition



Revenues from the sales of our products
are recognized when persuasive evidence of an arrangement exists, title and risk of loss have passed to the buyer, the price is
fixed or readily determinable and collection is reasonably assured.



During 2011 and 2010, we entered into
several distribution agreements for various geographic locations with third parties. Under the terms of some of the agreements,
we sell products to the distributor at a base price that is the greater of a fixed amount (as defined in each agreement) or 50%
of the distributor’s invoiced Net Sales price (as defined) to its customers. The distributor is required to provide us quarterly
reconciliations of the distributor’s actual invoiced prices at which time the price becomes fixed and determinable by us.
Until the price is fixed and determinable, we defer the recognition of revenues under these arrangements.



As of December 31, 2011 and 2010, the
Company had $0 and $24,750, respectively, of deferred revenue related to these arrangements recorded in the accompanying consolidated
balance sheets.



Any provision for sales promotion discounts
and estimated returns are estimated and accounted for in the period the related sales are recorded. Buyers generally have limited
rights of return, and the Company provides for estimated returns at the time of sale based on historical experience. Returns from
customers historically have not been material. Actual returns and claims in any future period may differ from the Company’s
estimates.



Accounting for Shipping and Handling Revenue, Fees and Costs



The Company classifies amounts billed
for shipping and handling as revenue in accordance with Financial Accounting Standards Board (“FASB”)  Accounting
Standards Codification (“ASC”) 605-45-50-2, Shipping and Handling Fees and Costs(“ASC 605-45-50-2”).
Shipping and handling fees and costs are included in cost of sales.



Page 57 of 132







Product Research and Development



Internal product research and development
costs are expensed as incurred. Non-refundable third party product research and development costs are expensed when the contracted
work has been performed. Product research and development costs were $115,476 and $673,918 for the years ended December 31, 2011
and 2010, respectively.



Allowance for Doubtful Accounts



The Company evaluates the collectability
of accounts receivable based on a combination of factors. In cases where the Company is aware of circumstances that may impair
a specific customer’s ability to meet its financial obligations subsequent to the original sale, the Company will record
an allowance against amounts due, and thereby reduce the net recognized receivable to the amount the Company reasonably believes
will be collected. For all other customers, the Company records allowances for doubtful accounts based primarily on the length
of time the receivables are past due based on the terms of the originating transaction, the current business environment, and
its historical experience. Uncollectible accounts are charged against the allowance for doubtful accounts when all cost effective
commercial means of collection have been exhausted.



Inventories



Inventories are valued at the lower of
cost or net realizable value. Cost is determined on an average cost basis which approximates actual cost on a first-in, first-out
basis and includes raw materials, labor and manufacturing overhead. At each balance sheet date, the Company evaluates its ending
inventories for excess quantities and obsolescence. The Company considers historical demand and forecast in relation to the inventory
on hand, market conditions and product life cycles when determining obsolescence and net realizable value. Provisions are made
to reduce excess or obsolete inventories to their estimated net realizable values. Once established, write-downs are considered
permanent adjustments to the cost basis of the excess or obsolete inventories.



Property and Equipment



Property and equipment is stated at cost. Depreciation is computed
using the straight-line method over estimated useful lives as follows:



|Machinery and equipment, including lab equipment | 5 to 15 years
|------------------------------------------------ | -------------
|Office equipment                                 | 3 to 10 years



Maintenance and repairs are charged to
expense as incurred. Renewals and improvements of a major nature are capitalized. At the time of retirement or other disposition
of property and equipment, the cost and accumulated depreciation are removed from the accounts and any resulting gains or losses
are reflected in the consolidated statement of operations.



Intangible Assets



The Company owns intellectual property
rights and an assignment of a US patent application for its CIT technology. The technology was purchased from Dr. Lung-Ji Chang,
who developed it while at the University of Alberta, Edmonton, Canada. The purchase price was being amortized over the expected
useful life of the technology, which the Company determined to be 20 years, based upon an estimate of three years to perfect the
patent plus 17 years of patent life. The CIT Technology was fully impaired as of December 31, 2010 due to the lack of any potential
future revenue and future cash flows, the high cost of future clinical studies, and limited time remaining on the patent.



Impairment of Long-Lived Assets



In accordance with FASB ASC 360-10-5,
Accounting for the Impairment or Disposal of Long-Lived Assets, the Company evaluates the carrying value of its
long-lived assets for impairment whenever events or changes in circumstances indicate that such carrying values may not be recoverable.
The Company uses its best judgment based on the current facts and circumstances relating to its business when determining whether
any significant impairment factors exist. The Company considers the following factors or conditions, among others, that could
indicate the need for an impairment review:



Page 58 of 132







| | • | significant under performance relative to expected historical or projected future operating results;
| | - | ----------------------------------------------------------------------------------------------------
| | • | market projections for cancer research technology;                                                  

| | • | its ability to obtain patents, including continuation patents, on technology;          
| | - | ---------------------------------------------------------------------------------------
| | • | significant changes in its strategic business objectives and utilization of the assets;

| | • | significant negative industry or economic trends, including legal factors;              
| | - | ----------------------------------------------------------------------------------------
| | • | potential for strategic partnerships for the development of its patented technology; and

| | • | ability to maintain Good Manufacturing Process (“GMP”) certifications.
| | - | ----------------------------------------------------------------------



If the Company determines that the carrying
values of long-lived assets may not be recoverable based upon the existence of one or more of the above indicators of impairment,
the Company’s management performs an undiscounted cash flow analysis to determine if impairment exists. If impairment exists,
the Company measures the impairment based on the difference between the asset’s carrying amount and its fair value, and
the impairment is charged to operations in the period in which the long-lived asset impairment is determined by management.



Based on its analysis, the Company impaired
the carrying value of its long-lived assets as of December 31, 2010. There can be no assurance, however, that market conditions
will not change or demand for the Company’s products will continue or allow the Company to realize the value of its long-lived
assets and prevent future impairment.



The carrying value of the Company’s
investment in JPI represents its ownership interest in JPI, accounted for under the cost method. The ownership interest is not
adjusted to fair value on a recurring basis. Each reporting period the Company assesses the fair value of the Company’s
ownership interest in JPI in accordance with FASB ASC 325-20-35. Each year the Company conducts an impairment analysis in accordance
with the provisions within FASB ASC 320-10-35 paragraphs 25 through 32. As of December 31, 2010, the Company fully impaired the
balance of its investment in JPI (see above).



Risks and Uncertainties



The Company’s proprietary test kit
is deemed a medical device or biologic, and as such is governed by the Federal Food and Drug and Cosmetics Act and by the regulations
of state agencies and various foreign government agencies.



On July 3, 2008, the Company received
a letter of determination from the USFDA that the Onko-Sure® test kit was “substantially equivalent” to the existing
predicate device being marketed. The letter grants the Company the right to market the Onko-Sure® test kit as a device to
monitor patients who have been previously diagnosed with colorectal cancer. The Company has received regulatory approval from
various foreign governments to sell its products and is in the process of obtaining regulatory approval in other foreign markets.
There can be no assurance that the Company will maintain the regulatory approvals required to market its Onko-Sure® test kit
or that they will not be withdrawn.



Although the Company has obtained approval
from the USFDA to market the then current formulation of the Onko-Sure® test kit, it has been determined that one of the key
components of the Onko-Sure® test kit, the anti-fibrinogen-HRP is limited in supply and additional quantities cannot be purchased.
Currently, we have two lots remaining which are estimated to produce approximately 21,000 kits. In order to utilize in kits, we
will need to purify and quality control the lots. We currently have enough purified and quality checked anti-fibrinogen-HRP to
manufacture 200 kits. Based on our current and anticipated orders, this supply is adequate to fill all orders in hand. Although
we are investigating alternatives or outsourcing this component so that we are in a position to have an unlimited supply of Onko-Sure®
in the future, we cannot assure that this anti-fibrinogen-HRP replacement will be completed.



The Company is subject to the risk of
failure in maintaining its existing regulatory approvals, in obtaining other regulatory approval, as well as the delays until
receipt of such approval, if obtained. Therefore, the Company is subject to substantial business risks and uncertainties inherent
in such an entity, including the potential of business failure.



Page 59 of 132







Share-Based Compensation



The Company accounts for equity instruments
issued to consultants and vendors in exchange for goods and services in accordance with the provisions of FASB ASC 505-50-30,
Equity-Based Payments to Non-Employees,(“ASC 505-50-30”) the measurement date for the fair value of the equity
instruments issued is determined at the earlier of (i) the date at which a commitment for performance by the consultant or vendor
is reached or (ii) the date at which the consultant or vendor’s performance is complete. In the case of equity instruments
issued to consultants, the fair value of the equity instrument is recognized over the term of the consulting agreement.



The Company has employee compensation
plans under which various types of share-based instruments are granted. The Company accounts for its share-based payments to employees
and directors in accordance with FASB ASC 718-10, “Stock Compensation” (“ASC 718-10”). ASC 718-10
requires all share-based payments to employees, including grants of employee stock options, to be measured based upon their grant
date fair value, and be recognized in the statements of operations as compensation expense (based on their estimated fair values)
generally over the vesting period of the awards.





As of December 31, 2011, the Company did
not have sufficient authorized shares of common stock for issuance to certain consultants for services; as a result, the Company
recorded the value of the remaining common stock issuable as accrued share-based compensation of $1,816,965 (see Note 16).





Basic and Diluted Loss Per Share



Basic net loss per common share from operations
is computed based on the weighted-average number of shares outstanding for the period. Diluted net loss per share from operations
is computed by dividing net loss by the weighted-average shares outstanding assuming all dilutive potential common shares were
issued. In periods of losses from operations, basic and diluted loss per share are the same as the effect of shares issuable upon
the conversion of debt and issuable upon the exercise of stock options and warrants is anti-dilutive. The following table sets
forth the computation of basic and diluted net loss per share, including the reconciliation of the numerator and denominator used
in the calculation of basic and diluted net loss per share:





|                                                              |  | For the year ended
 December 31, |            
|------------------------------------------------------------- |  | -------------------------------- | -----------
|                                                              |  | 2011                             |            
|Basic and diluted net loss per share:                         |  |                                  |            
|Numerator:                                                    |  |                                  |            
|                                                              |  |                                  |            
|                                                              |  |                                  |            
|Net loss                                                      |  | $                                | (86,187,269
|                                                              |  |                                  |            
|Denominator:                                                  |  |                                  |            
|Weighted-average common shares outstanding, basic and diluted |  |                                  | 12,612,759 
|                                                              |  |                                  |            
|Basic and diluted net loss per share:                         |  |                                  |            
|                                                              |  |                                  |            
|                                                              |  |                                  |            
|Net loss                                                      |  | $                                | (6.83      



The following table sets
forth potentially dilutive common share equivalents, consisting of shares issuable upon the exercise or vesting of
outstanding stock options and restricted stock awards, respectively, and the exercise of warrants, computed using the
treasury stock method, as well as the conversion of debt, accrued interest and preferred stock. These potential common shares have
been excluded from the diluted net loss per share calculations above as their effect would be anti-dilutive for the years
then ended:



|                         |  | For the year ended
 December 31, |            
|------------------------ |  | -------------------------------- | -----------
|                         |  | 2011                             |            
|Common share equivalents |  |                                  | 646,894,783



The above common share equivalents would have been included
in the calculation of diluted earnings per share had the Company reported net income for the years ended December 31, 2011 and
2010.



Page 60 of 132







Income Taxes



The Company accounts for income taxes
under FASB ASC 740-10, Income Taxes (“ASC 740-10”). Under ASC 740-10, deferred tax assets
and liabilities are recognized for the future tax consequences attributable to differences between the financial statement carrying
amounts of existing assets and liabilities and their respective tax bases. Deferred tax assets and liabilities are measured using
enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered
or settled. A valuation allowance is provided for significant deferred tax assets when it is more likely than not that such assets
will not be recovered.



When tax returns are filed, it is highly
certain that some positions taken would be sustained upon examination by the taxing authorities, while others are subject to uncertainty
about the merits of the position taken or the amount of the position that would be ultimately sustained. The benefit of a tax
position is recognized in the financial statements in the period during which, based on all available evidence, management believes
it is more likely than not that the position will be sustained upon examination, including the resolution of appeals or litigation
processes, if any. Tax positions taken are not offset or aggregated with other positions. Tax positions that meet the more-likely-than-not
recognition threshold are measured as the largest amount of tax benefit that is more than 50 percent likely of being realized
upon settlement with the applicable taxing authority. The portion of the benefits associated with tax positions taken that exceeds
the amount measured as described above is reflected as a liability for unrecognized tax benefits in the accompanying consolidated
balance sheets along with any associated interest and penalties that would be payable to the taxing authorities upon examination.
The Company recognizes interest and penalties as a component of income tax expense.



At December 31, 2011 and 2010, the Company has accrued zero
for the payment of tax related interest and there was no tax interest or penalties recognized in the consolidated statements of
operations.



Fair Value of Financial Instruments



The carrying amounts of the Company’s
cash, accounts receivable, accounts payable and accrued expenses approximate their estimated fair values due to the short-term
maturities of those financial instruments. The Company believes the carrying amount of its notes payable and convertible debt
approximates its fair value based on rates and other terms currently available to the Company for similar debt instruments.



Beneficial Conversion Feature



In certain instances, the Company enters
into convertible notes that provide for an effective or actual rate of conversion that is below market value, and the embedded
conversion feature does not qualify for derivative treatment (a “BCF”). In these instances, the Company accounts for
the value of the BCF as a debt discount, which is then amortized to interest expense over the life of the related debt using the
straight-line method which approximates the effective interest method.



Derivative Financial Instruments



We apply the provisions of FASB ASC 815-10,
Derivatives and Hedging (“ASC 815-10”). Derivatives within the scope of ASC 815-10 must be recorded on the
balance sheet at fair value. During the year ended December 31, 2011 and 2010, we issued convertible debt and preferred stock
with warrants and recorded derivative liabilities related to a reset provision associated with the embedded conversion feature
of the convertible debt and preferred stock and a reset provision associated with the exercise price of the warrants. We compute
the fair value of these derivative liabilities on the grant date and various measurement dates using the Binomial Lattice option
pricing model. Due to the reset provisions within the embedded conversion feature and a reset provision associated with the exercise
price of the warrants, we have determined that the Binomial Lattice Model was most appropriate for valuing these instruments.



On May 24, 2011, it was determined that
the Company had insufficient authorized shares which resulted in the Company having to reclassify the conversion features of the
remaining convertible debt, non-employee options, and warrants as derivative liabilities. As these instruments carried fixed conversion
features and exercise prices, the Company determined it was appropriate to use the Black-Scholes valuation model to value these
options, warrants and conversion features.



In applying the Binomial Lattice model, the Company used the
following assumptions to value its derivative liabilities during the year ended December 31, 2011:



Page 61 of 132







|                        |  | For the year                    |  |  |  | For the year                   
|----------------------- |  | ------------------------------- |  |  |  | -------------------------------
|                        |  | ended December 31,
        2011 |  |  |  | ended December 31,
        2010
|Annual dividend yield   |  | —                               |  |  |  | —                              
|Expected life (years)   |  | 0.02 – 5.86                     |  |  |  | 0.22 – 6.17                    
|Risk-free interest rate |  | 0.01% — 2.5%                    |  |  |  | 0.11% — 2.9%                   
|Expected volatility     |  | 104.4% — 310.1%                 |  |  |  | 87.3% — 298.6%                 



In applying the Black-Scholes valuation model, the Company
used the following assumptions during  the year ended December 31, 2011:



|                        |  | For the year                    | 
|----------------------- |  | ------------------------------- | 
|                        |  | ended December 31,
        2011 | 
|Annual dividend yield   |  | -                               | 
|Expected life (years)   |  | 3.00 – 5.00                     | 
|Risk-free interest rate |  | 0.38% — 0.88%                   | 
|Expected volatility     |  | 156.5.% — 192.4%                | 





For the warrants that include optional
cashless exercise provisions, the Company applied a 90%/10% and 0%/100% (the most profitable exercise provision to the holder)
probability that the holder will exercise under either the cashless exercise or the cash exercise scenario, for the warrants related
to the 2011 and 2010 financing instruments, respectively. The cashless exercise provision expires once the underlying warrant
shares are registered. As of December 31, 2011, no warrants were registered (See Note 16 Subsequent Events).



If the inputs used to measure fair value
fall in different levels of the fair value hierarchy, a financial security’s hierarchy level is based upon the lowest level
of input that is significant to the fair value measurement.



The Company determines the fair value
of its derivative instruments using a three-level hierarchy for fair value measurements which these assets and liabilities must
be grouped, based on significant levels of observable or unobservable inputs. Observable inputs reflect market data obtained from
independent sources, while unobservable inputs reflect the Company’s market assumptions. This hierarchy requires the use
of observable market data when available. These two types of inputs have created the following fair-value hierarchy:



Level 1—
Valuation based on unadjusted quoted market prices in active markets for identical securities. Currently, the Company does not
have any items as Level 1.



Level 2—
Valuations based on observable inputs (other than Level 1 prices), such as quoted prices for similar assets at the measurement
date; quoted prices in markets that are not active; or other inputs that are observable, either directly or indirectly. Currently,
the Company does not have any items classified as Level 2.



Level 3—
Valuations based on inputs that are unobservable and significant to the overall fair value measurement, and involve management
judgment. The Company used Binominal Lattice and Black-Scholes option pricing models to determine the fair value of the instruments.



The following table presents the Company’s
non-employee options, warrants, and embedded conversion features of its convertible debt and preferred stock measured at fair
value on a recurring basis as of December 31, 2011:



|                                               |  | Level 3           |           
|---------------------------------------------- |  | ----------------- | ----------
|                                               |  | Carrying Value at |           
|                                               |  | December 31,      |           
|                                               |  | 2011              |           
|                                               |  |                   |           
|Derivative liabilities:                        |  |                   |           
|Embedded conversion features - notes           |  | $                 | 8,744,067 
|Embedded conversion features – preferred stock |  |                   | 5,829,594 
|Warrants and non-employee options              |  |                   | 23,793,106
|Total derivative liabilities                   |  | $                 | 38,366,767



Page 62 of 132









|                                                             |  | For the year ended |           
|------------------------------------------------------------ |  | ------------------ | ----------
|                                                             |  | December 31,       |           
|                                                             |  | 2011               |           
|Change in fair value included in other income (expense), net |  | $                  | 37,204,639



The following table provides a reconciliation
of the beginning and ending balances for the Company’s derivative liabilities measured at fair value using Level 3 inputs:



|                                                                                                        |  | For the year ended |            
|------------------------------------------------------------------------------------------------------- |  | ------------------ | -----------
|                                                                                                        |  | December 31,       |            
|                                                                                                        |  | 2011               |            
|                                                                                                        |  |                    |            
|Embedded Conversion Features - Notes:                                                                   |  |                    |            
|Balance at beginning of year                                                                            |  | $                  | 7,912,388  
|Derivative liabilities added                                                                            |  |                    | 22,290,800 
|Reclassification to equity in connection with conversion of underlying debt to equity                   |  |                    | (17,414,270
|Net change in fair value included in net loss                                                           |  |                    | (4,044,851 
|Ending balance                                                                                          |  | $                  | 8,744,067  
|                                                                                                        |  |                    |            
|Embedded Conversion Features - Preferred Stock:                                                         |  |                    |            
|Balance at beginning of year                                                                            |  | $                  | -          
|Derivative liabilities added                                                                            |  |                    | 13,169,834 
|Reclassification to equity in connection with conversion or exchanged of underlying preferred
    stock |  |                    | (9,334,375 
|Net change in fair value included in net loss                                                           |  |                    | 1,994,135  
|Ending balance                                                                                          |  | $                  | 5,829,594  
|Warrants and non-employee options:                                                                      |  |                    |            
|Balance at beginning of year                                                                            |  | $                  | 21,153,476 
|Derivative liabilities added                                                                            |  |                    | 59,732,184 
|Reclassification to equity in connection with exercise of underlying stock warrants                     |  |                    | (21,938,631
|Net change in fair value included in net loss                                                           |  |                    | (35,153,923
|Ending balance                                                                                          |  | $                  | 23,793,106 
|                                                                                                        |  |                    |            
|Total ending balance                                                                                    |  | $                  | 38,366,767 



Page 63 of 132







During the years ended December 31, 2011
and 2010, several holders of the Company’s convertible debt and preferred stock converted portions of their notes and accrued
interest into shares of the Company’s common stock. This resulted in a reclassification of the derivative liability of $26,748,645
and $566,159, respectively, to additional paid-in capital, representing the fair value of the embedded conversion features of
the converted debt and preferred stock. In addition, during the years ended December 31, 2011 and 2010, holders of the Company`s
convertible debt exercised or forfeited through exchange transactions warrants. This resulted in a reclassification of the derivative
liability of $21,938,631 and $754,870, respectively, representing the fair value of the warrants immediately prior to the exercise.



During the year ended December 31, 2010,
the Company recorded additional derivative liabilities of $20,665,620 as a result of embedded conversion features of the convertible
debt and warrants with down-round protection features, accrued interest, trigger events, and penalties related to the 2010 Closings
(see Note 8).



During the year ended December 31, 2011,
the Company recorded additional derivative liabilities of $95,192,818 as a result of embedded conversion features of the convertible
debt, preferred stock and warrants with down-round protection features, accrued interest, trigger events, and penalties related
to legal settlements, 2010 Closings and 2011 Financings (see Note 8).



The Company re-measures the fair values
of all of its derivative liabilities as of each period end and records the net aggregate loss due to the change in the fair value
of the derivative liabilities as a component of other expense, net in the accompanying consolidated statement of operations. During
the years ended December 31, 2011 and 2010, the Company recorded a net (increases) decrease to the fair value of derivative liabilities
balance of $37,204,639 and $(9,366,515), respectively and is included in selling, general and administrative expenses.



Advertising Costs



Advertising costs are expensed as
incurred. Advertising costs were approximately $127,000 and $32,000 for the years ended December 31, 2011 and 2010,
respectively and is included in selling, general and administrative expenses.



Concentrations of Credit Risk



Cash



From time to time, the Company maintains
cash balances at certain institutions in excess of the FDIC limit. As of December 31, 2011, the Company had no cash balances in
excess of this limit.



Customers



The Company’s ability to collect
receivables is affected by economic fluctuations in the geographic areas and the industry served by the Company. A reserve for
uncollectible amounts and estimated sales returns is provided based on historical experience and a specific analysis of the accounts.
Accounts receivable is $6,835 and $2,603 at December 31, 2011 and 2010. The Company determined that an allowance for doubtful
accounts was not necessary at December 31, 2011 or December 31, 2010.



Page 64 of 132







Supplemental Cash Flow Information



|                                                                                                       |  | For the Year
    Ended |            |  | For the Year
    Ended |  
|------------------------------------------------------------------------------------------------------ |  | ---------------------- | ---------- |  | ---------------------- | -
|                                                                                                       |  | December
    31, 2011  |            |  | December
    31, 2010  |  
|                                                                                                       |  |                        |            |  |                        |  
|Supplemental disclosure of cash flow information:                                                      |  |                        |            |  |                        |  
|Cash
    paid during the year for interest                                                             |  | $                      | 127,955    |  |                        | $
|Cash
    paid during the year for taxes                                                                |  | $                      | -          |  |                        | $
|                                                                                                       |  |                        |            |  |                        |  
|Supplemental disclosure of non-cash investing
    and financing activities:                            |  |                        |            |  |                        |  
|                                                                                                       |  |                        |            |  |                        |  
|Voluntary
    conversion of preferred stock, convertible debt and accrued interest                     |  | $                      | 32,855,984 |  |                        | $
|Fair
    value of common stock and warrants issued recorded as prepaid consulting                      |  | $                      | 106,000    |  |                        | $
|Fair
    value of warrants recorded as prepaid consulting accounted for as derivatives                 |  | $                      | 728,907    |  |                        | $
|Fair
    value of stock issued in connection with JPI guarantee                                        |  | $                      | 1,086,583  |  |                        | $
|Fair
    value of stock issued in connection with settlement                                           |  | $                      | 140,400    |  |                        | $
|Issuance
    of previously accrued fair value of stock to consultants                                  |  | $                      | 745,432    |  |                        | $
|Reclassification
    of derivative liabilities to equity                                               |  | $                      | 48,687,276 |  |                        | $
|Reclassification
    to derivative liabilities from equity due to insufficient shares                  |  | $                      | 1,524,631  |  |                        | $
|Conversion
    of warrants to common stock (cashless)                                                  |  | $                      | 24,138     |  |                        | $
|Debt
    discounts and issuance costs related to derivative liabilities                                |  | $                      | 29,011,604 |  |                        | $
|Debt
    issuance costs and OID related to 2011 Financing                                              |  | $                      | 1,617,500  |  |                        | $
|2011
    Financing Debt Exchange                                                                       |  | $                      | 30,494,200 |  |                        | $
|Beneficial
    conversion feature of Series 1 and 2 Convertible Notes                                  |  | $                      | 4,441,563  |  |                        | $
|Amounts
    paid directly from proceeds in connection with convertible debt unrelated to the financing |  | $                      | -          |  |                        | $
|Conversion
    of accounts payable to stock                                                            |  | $                      | -          |  |                        | $
|Beneficial
    conversion feature recorded as debt discount                                            |  | $                      | -          |  |                        | $
|Additional
    derivative liability for interest and penalties on debt                                 |  | $                      | -          |  |                        | $





Recent Accounting Pronouncements



New pronouncements issued but not effective until after December
31, 2011, are not expected to have a significant effect on our consolidated financial statements.





NOTE 2 — INVENTORIES



Inventories consist of the following:



|                |  | December 31, |       
|--------------- |  | ------------ | ------
|                |  | 2011         |       
|Raw materials   |  | $            | 66,091
|Work-in-process |  |              | 23,545
|Finished goods  |  |              | 151   
|                |  | $            | 89,787





Page 65 of 132







NOTE 3 — NOTE RECEIVABLE



On August 27, 2010, the Company advanced
$95,000 to Provista Diagnostic, Inc. (“Provista”), as a note receivable. In addition, the note included $5,000 in
origination fees. In connection with the note receivable agreement, Provista agreed to deliver two separate research reports to
the Company by September 30, 2010 as full satisfaction of the balance owed. If the reports were not delivered to the Company by
September 30, 2010, the agreement called for a 25% increase in the principal balance. Due to Provista’s failure to deliver
such reports by September 30, 2010, the Company recorded interest income of $26,327, which represents the 25% increase from the
principal balance of the note plus accrued interest of $1,062. If the research reports were not delivered to the Company by September
30, 2010, then the note required five equal payments of $20,000 (totaling $100,000) on the 1st day of each month commencing on
the initial interest payment date (as defined in the note) and continuing thereafter until maturity (August 27, 2011). Interest
accrued on the unpaid principal balance at a rate of 12% per annum until September 30, 2010. After this date, if the reports were
not delivered interest began to accrue at the rate of 18% per annum.



On October 8, 2010, the required research
reports were provided to the Company as satisfaction on the principal of the note. The accrued penalty and interest of $33,046
remains unpaid as of December 31, 2010. In the light of the overall economic crisis, our intended long-term relationship going
forward with Provista, and the fact that as of the date of this report the balance was not collected, the Company considered the
balance uncollectible and reversed the remaining balance against interest income as of December 31, 2010.



NOTE 4 — PROPERTY AND EQUIPMENT



Property and equipment consists of the following:



|                               |  | December 31, |         
|------------------------------ |  | ------------ | --------
|                               |  | 2011         |         
|Office equipment               |  | $            | 151,867 
|Lab equipment                  |  |              | 98,191  
|                               |  |              | 250,058 
|Less: accumulated depreciation |  |              | (184,373
|                               |  | $            | 65,685  



Depreciation expense was $40,736 and $35,575 for the years
ended December 31, 2011 and 2010, respectively.



NOTE 5 — INTANGIBLE ASSETS



Intangible assets consist of the following:



|                           |  | December 31 |           
|-------------------------- |  | ----------- | ----------
|                           |  | 2010        |           
|Intellectual Property      |  | $           | 2,000,000 
|Additions                  |  |             | -         
|Impairment                 |  |             | (1,058,333
|Accumulated Amortization   |  |             | (941,667  
|Net balance at end of year |  | $           | -         



In August 2001, the Company acquired intellectual
property rights and an assignment of a US patent application for combination immunogene therapy (“CIT”) technology
for $2,000,000. The technology was purchased from Dr. Lung-Ji Chang, who developed it while at the University of Alberta, Edmonton,
Canada. During 2003, two lawsuits were filed challenging the Company’s ownership of this intellectual property. In October
2011, these lawsuits were dismissed. However, the dismissals are being appealed and the Company does not have funds necessary
to retain Canadian attorneys to dispute this appeal.



Page 66 of 132







As part of the acquisition of the CIT
technology, the Company agreed to pay Dr. Chang a 5% royalty on net sales of combination gene therapy products. The Company has
not paid any royalties to Dr. Chang to date as there have been no sales of combination gene therapy products.



Based on a valuation analysis, and due
to the lack of any potential future revenue and future cash flows, the high cost of future clinical studies, and limited time
remaining on the patent, the Company determined that the carrying value of the intangible asset had been impaired and accordingly
recorded an impairment of the intangible asset of $1,058,333 as of December 31, 2010 in the accompanying consolidated statement
of operations.



During the year ended December 31, 2010,
amortization expense totaled $100,000. The intellectual property was being amortized over the life of the patent of 20 years.



NOTE 6 — PREPAID EXPENSES, OTHER CURRENT ASSETS, AND
OTHER ASSETS



Prepaid expenses and other current assets consist of the following:



|                       |  | December 31, |        
|---------------------- |  | ------------ | -------
|                       |  | 2011         |        
|Prepaid insurance      |  | $            | 89,090 
|Legal retainers        |  |              | 7,436  
|Other                  |  |              | 45,362 
|Total prepaid expenses |  | $            | 141,888



Other assets for the year ended December
31, 2010 consist of the refundable deposit of $5,370.



NOTE 7 — INCOME TAXES



The Company and its subsidiaries are included
in a consolidated Federal income tax return. For the year ended December 31, 2011, the Company’s international subsidiaries
filed various income tax returns in their tax jurisdictions. As previously stated, the Company deconsolidated its China subsidiary,
JPI, effective September 29, 2009. The provision for income taxes is as follows:



|                                 |  | 2011 |   |  | 2010 |  
|-------------------------------- |  | ---- | - |  | ---- | -
|Current:                         |  |      |   |  |      |  
|Federal                          |  | $    | - |  |      | $
|State                            |  |      | - |  |      |  
|Total current                    |  |      | - |  |      |  
|                                 |  |      |   |  |      |  
|Deferred                         |  |      | - |  |      |  
|Total provision for income taxes |  | $    | - |  |      | $



The Company’s loss before income tax provision was subject
to taxes in the following jurisdictions for the following periods:



|              |  | 2011 |             |   | 2010 |  
|------------- |  | ---- | ----------- | - | ---- | -
|Pretax loss:  |  |      |             |   |      |  
|United States |  | $    | (86,187,269 | ) |      | $
|Foreign       |  |      | -           |   |      |  
|              |  | $    | (86,187,269 | ) |      | $



The provision (benefit) for income taxes
differs from the amount computed by applying the U.S. Federal income tax rate of 34% to loss before income taxes as a result of
the following for the years ended December 31:



|                                                 |  | 2011 |             |   | 2010 |  
|------------------------------------------------ |  | ---- | ----------- | - | ---- | -
|Computed tax benefit at federal statutory rate   |  | $    | (29,304,000 | ) |      | $
|State income tax benefit, net of federal benefit |  |      | 1,000       |   |      |  
|Nondeductible interest expense                   |  |      | 19,171,000  |   |      |  
|Fair value adjustments to derivatives            |  |      | (12,650,000 | ) |      |  
|Loss on extinguishment of debt                   |  |      | 15,597,000  |   |      |  
|NQSO Expirations                                 |  |      | 1,108,000   |   |      |  
|Tax credits                                      |  |      | (7,000      | ) |      |  
|Expired net operating losses                     |  |      | 552,000     |   |      |  
|Change in valuation allowance                    |  |      | 5,524,000   |   |      |  
|Other                                            |  |      | 8,000       |   |      |  
|                                                 |  | $    | -           |   |      | $



Page 67 of 132







The components of the Company’s
deferred tax assets and liabilities are as follows:



|                                                         |  | December 31, |            
|-------------------------------------------------------- |  | ------------ | -----------
|                                                         |  | 2011         |            
|Deferred tax asset:                                      |  |              |            
|Net operating loss carryforwards                         |  | $            | 25,114,000 
|Expenses recognized for granting of options and warrants |  |              | 1,806,000  
|Tax credit carryforwards                                 |  |              | 346,000    
|Depreciation                                             |  |              | 418,000    
|Deferred gain on JPI                                     |  |              | 2,551,000  
|Book write-off of JPI note                               |  |              | 1,146,000  
|Other temporary differences                              |  |              | 5,557,000  
|Total gross deferred tax asset                           |  |              | 36,938,000 
|Valuation allowance                                      |  |              | (33,278,000
|Net deferred tax asset                                   |  |              | 3,660,000  
|                                                         |  |              |            
|Deferred tax liabiltities:                               |  |              |            
|Unamortized debt discount                                |  |              | (3,660,000 
|Total deferred tax liabilities                           |  |              | (3,660,000 
|Net deferred tax asset                                   |  | $            | -          



The Company records a valuation allowance
to reduce the carrying value of the net deferred tax assets to an amount that is more likely than not to be realized. The valuation
allowance increased by approximately $7,107,000 during the year ended December 31, 2011.



The federal and state net operating loss
carry forward expire on various dates through 2025, unless previously utilized. The Company does not have any net operating losses
that are attributable to excess stock option deductions which would be recorded as an increase in additional paid in-capital when
realized. The Company has research and development tax credit carry forwards of approximately $172,000 and $174,000 to reduce
federal and state income tax, respectively. The federal research and development tax credits will begin to expire in 2022, unless
previously utilized. The Company’s California research and development tax credit carry forwards do not expire and will
carry forward indefinitely until utilized. Any net operating loss or credit carry forwards that will expire prior to utilization
will be removed from deferred tax assets with a corresponding reduction of the valuation allowance.



Page 68 of 132







Utilization of the net operating loss
and research and development credit carry forwards may be subject to a substantial annual limitation due to ownership change limitations
that have occurred previously or that could occur in the future as provided by Sections 382 and 383 of the Internal Revenue Code
of 1986, as well as similar state and foreign provisions. These ownership changes may limit the amount of net operating loss and
research and development credit carry forwards than can be utilized annually to offset future taxable income and tax, respectively.
In general, an ownership change, as defined by Section 382, results from transactions increasing the ownership of certain shareholders
or public groups in the stock of a corporation by more than 50 percentage points over a three-year period. Since the Company’s
formation, the Company has raised capital through the issuance of capital stock on several occasions which, combined with dispositions
of shares, may have resulted in a change of control, or could result in a change of control when combined with future transactions.
The Company has not currently completed a study to assess whether a change or changes in control have occurred due to the significant
complexity and cost associated with such a study. Any limitation may result in expiration of a portion of the net operating loss
or research and development credit carry forwards before utilization.



On January 1, 2007 the Company adopted
the provisions of ASC 740-10-05-6. As a result of applying the provisions of ASC 740-10-05-6, the Company increased
its liability for unrecognized tax benefits by approximately $123,000, offsetting the valuation allowance on net deferred tax
assets. Interest or penalties have not been accrued at December 31, 2011 or 2010. If tax benefits are ultimately recognized, there
will be no impact to the Company’s effective tax rate as a result of the Company’s valuation allowance. The Company
does not anticipate any significant increases or decreases to its liability for unrecognized tax benefits within the next 12 month
period.



A reconciliation of the beginning and
ending amount of unrecognized tax benefits (which are not recorded as a liability because they are offset by net operating loss
carry forwards) follows:



|                                                                     |  | 2011 |        |  | 2010 |  
|-------------------------------------------------------------------- |  | ---- | ------ |  | ---- | -
|Unrecognized Tax Benefits:                                           |  |      |        |  |      |  
|Balance at beginning of year                                         |  | $    | 54,000 |  |      | $
|Increase/(decrease) for tax provisions
    taken in prior years, net |  |      | -      |  |      |  
|Balance at end of year                                               |  | $    | 54,000 |  |      | $



The Company is no longer subject to U.S.
federal and state income tax examinations for years before 2007 and 2006, respectively. However, to the extent allowed by law,
the tax authorities may have the right to examine prior periods where net operating losses or tax credits were generated and carried
forward, and make adjustments up to the amount of the net operating loss or credit carry forward amount the Company has in fiscal
years 2008, 2009, and 2010 open for federal and 2007, 2008, 2009, and 2010 for state income tax examinations, respectively. The
Company is not currently under Internal Revenue Service or state tax examinations.



Page 69 of 132









NOTE 8 — DEBT



Debt consists of the following:



|                                                                                                                                                                                                                                                               |  | December 31, |           |  | December 31, |  
|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |  | ------------ | --------- |  | ------------ | -
|                                                                                                                                                                                                                                                               |  | 2011         |           |  | 2010         |  
|                                                                                                                                                                                                                                                               |  |              |           |  |              |  
|Debt:                                                                                                                                                                                                                                                          |  |              |           |  |              |  
|                                                                                                                                                                                                                                                               |  |              |           |  |              |  
|Convertible Notes issued September 2008                                                                                                                                                                                                                        |  | $            | 46,442    |  |              | $
|                                                                                                                                                                                                                                                               |  |              |           |  |              |  
|First Closing of 2010 Convertible Note, issued March 22, 2010, including additional $1,410,422
    principal and interest for trigger events, forbearance penalty, and debt extinguishment                                                                     |  |              | -         |  |              |  
|                                                                                                                                                                                                                                                               |  |              |           |  |              |  
|Second Closing of 2010 Convertible Note, issued April 8, 2010, including additional $4,181,576
    principal and interest for trigger events, forbearance penalty, and debt extinguishment; net of unamortized discount of $1,466,389
    at December 31, 2010 |  |              | -         |  |              |  
|                                                                                                                                                                                                                                                               |  |              |           |  |              |  
|Third Closing of 2010 Convertible Note, issued April 13, 2010, including additional $3,546,386
    principal and interest for trigger events, forbearance penalty, and debt extinguishment; net of unamortized discount $749,428
    at  December 31, 2010     |  |              | -         |  |              |  
|                                                                                                                                                                                                                                                               |  |              |           |  |              |  
|Fourth Closing of 2010 Convertible Note, issued April 26, 2010, including additional $480,108
    principal and interest for trigger events; net of unamortized discount of $199,828 at December 31, 2010                                                      |  |              | -         |  |              |  
|                                                                                                                                                                                                                                                               |  |              |           |  |              |  
|Senior Notes (1)                                                                                                                                                                                                                                               |  |              | 25,000    |  |              |  
|                                                                                                                                                                                                                                                               |  |              |           |  |              |  
|Bridge note, including additional $104,138 principal and interest for penalties                                                                                                                                                                                |  |              | -         |  |              |  
|                                                                                                                                                                                                                                                               |  |              |           |  |              |  
|Legal Settlement Promissory Notes, issued May 24, 2011, including additional $234,554 principal
    for settlement                                                                                                                                             |  |              | 8,056,258 |  |              |  
|                                                                                                                                                                                                                                                               |  |              |           |  |              |  
|November 2011 Convertible Notes, issued November 28, 2011 in connection with the Exchange Agreement, 
    net of unamortized discount of $4,484,293 at December 31, 2011                                                                                       |  |              | 424,317   |  |              |  
|                                                                                                                                                                                                                                                               |  |              |           |  |              |  
|November 2011 Series B Convertible Preferred Stock, issued November 28, 2011 in connection with
    the Exchange Agreement,  net of unamortized discount of $3,604,351 at December 31, 2011                                                                    |  |              | 351,670   |  |              |  
|                                                                                                                                                                                                                                                               |  |              |           |  |              |  
|November 2011 Series C Convertible Preferred Stock, issued November 30,
    2011 after exercise of Series B warrants,  net of unamortized discount of $455,556 at December 31, 2011                                                                            |  |              | 44,444    |  |              |  
|                                                                                                                                                                                                                                                               |  |              |           |  |              |  
|Total debt, net of unamortized discount, all current                                                                                                                                                                                                           |  | $            | 8,948,131 |  |              | $



| | (1) | Due to the exchange agreement with the note payable holders, on
                                                           January 3, 2010, when NYSE Amex approval was received, these notes
                                                           became convertible notes payable.
| | --- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



During the year ended December 31, 2011,
convertible note holders converted an aggregate of $30,206,087 of principal and $2,649,897 of accrued interest into a total of
26,503,634 shares of the Company’s common stock.



The following table summarizes the conversion
of the notes and accrued interest.



Page 70 of 132







|Debt                                                   |  | Gross
    Principal Balance @ 12/31/10 |            |  | Principal
    Additions |   |            | Interest
    Accrued to Conversion or YTD |  |   | Principal
    Payment Amount |  |  | Principal
    Conversion Amount |            |   | Principal
    Exchanged Amount |   |             | Interest
    Conversion Amount |  |   | Gross
    Principal Balance @ 12/31/11 |   |  | Accrued
    Interest Balance @ 12/31/11 |            |   | Principal
    % Converted |   |            | Number
    of Shares Issued | 
|------------------------------------------------------ |  | -------------------------------------- | ---------- |  | ----------------------- | - | ---------- | ----------------------------------------- |  | - | ---------------------------- |  |  | ------------------------------- | ---------- | - | ------------------------------ | - | ----------- | ------------------------------ |  | - | -------------------------------------- | - |  | --------------------------------------- | ---------- | - | ------------------------- | - | ---------- | --------------------------- | 
|2008 Convertible 10% Debt                              |  | $                                      | 363,942    |  |                         | $ | -          |                                           |  | $ | 69,636                       |  |  | $                               | -          |   |                                | $ | (317,500    | )                              |  | $ | -                                      |   |  | $                                       | (53,555    | ) |                           | $ | 46,442     |                             | 
|                                                       |  |                                        |            |  |                         |   |            |                                           |  |   |                              |  |  |                                 |            |   |                                |   |             |                                |  |   |                                        |   |  |                                         |            |   |                           |   |            |                             | 
|2010 Financings:                                       |  |                                        |            |  |                         |   |            |                                           |  |   |                              |  |  |                                 |            |   |                                |   |             |                                |  |   |                                        |   |  |                                         |            |   |                           |   |            |                             | 
|1st Close                                              |  |                                        | 472,937    |  |                         |   | -          |                                           |  |   | 41,722                       |  |  |                                 | -          |   |                                |   | (472,937    | )                              |  |   | -                                      |   |  |                                         | (41,722    | ) |                           |   | -          |                             | 
|2nd Close                                              |  |                                        | 9,638,807  |  |                         |   | 32,934     |                                           |  |   | 727,626                      |  |  |                                 | -          |   |                                |   | (9,671,741  | )                              |  |   | -                                      |   |  |                                         | (697,842   | ) |                           |   | -          |                             | 
|3rd Close                                              |  |                                        | 7,283,971  |  |                         |   | 219,446    |                                           |  |   | 865,665                      |  |  |                                 | -          |   |                                |   | (7,503,417  | )                              |  |   | -                                      |   |  |                                         | (579,170   | ) |                           |   | -          |                             | 
|4th Close                                              |  |                                        | 1,165,278  |  |                         |   | -          |                                           |  |   | 85,721                       |  |  |                                 | -          |   |                                |   | (1,165,278  | )                              |  |   | -                                      |   |  |                                         | (80,042    | ) |                           |   | -          |                             | 
|                                                       |  |                                        | 18,560,993 |  |                         |   | 252,380    |                                           |  |   | 1,720,734                    |  |  |                                 | -          |   |                                |   | (18,813,373 | )                              |  |   | -                                      |   |  |                                         | (1,398,776 | ) |                           |   | -          |                             | 
|                                                       |  |                                        |            |  |                         |   |            |                                           |  |   |                              |  |  |                                 |            |   |                                |   |             |                                |  |   |                                        |   |  |                                         |            |   |                           |   |            |                             | 
|Senior Note Series 1                                   |  |                                        | 2,196,875  |  |                         |   | -          |                                           |  |   | 552,328                      |  |  |                                 | -          |   |                                |   | (2,196,875  | )                              |  |   | -                                      |   |  |                                         | (552,328   | ) |                           |   | -          |                             | 
|Senior Note Series 2                                   |  |                                        | 2,244,688  |  |                         |   | -          |                                           |  |   | 612,706                      |  |  |                                 | -          |   |                                |   | (2,219,688  | )                              |  |   | -                                      |   |  |                                         | (603,108   | ) |                           |   | 25,000     |                             | 
|                                                       |  |                                        | 4,441,563  |  |                         |   | -          |                                           |  |   | 1,165,034                    |  |  |                                 | -          |   |                                |   | (4,416,563  | )                              |  |   | -                                      |   |  |                                         | (1,155,436 | ) |                           |   | 25,000     |                             | 
|                                                       |  |                                        |            |  |                         |   |            |                                           |  |   |                              |  |  |                                 |            |   |                                |   |             |                                |  |   |                                        |   |  |                                         |            |   |                           |   |            |                             | 
|Bridge Note                                            |  |                                        | 140,360    |  |                         |   | -          |                                           |  |   | 25,474                       |  |  |                                 | -          |   |                                |   | (140,360    | )                              |  |   | -                                      |   |  |                                         | (25,474    | ) |                           |   | -          |                             | 
|                                                       |  |                                        |            |  |                         |   |            |                                           |  |   |                              |  |  |                                 |            |   |                                |   |             |                                |  |   |                                        |   |  |                                         |            |   |                           |   |            |                             | 
|A&W Legal Settlement Promissory Notes
    “RDO Notes”  |  |                                        | -          |  |                         |   | 11,006,208 |                                           |  |   | 224,251                      |  |  |                                 | -          |   |                                |   | (2,949,950  | )                              |  |   | -                                      |   |  |                                         | -          |   |                           |   | 8,056,258  |                             | 
|                                                       |  |                                        |            |  |                         |   |            |                                           |  |   |                              |  |  |                                 |            |   |                                |   |             |                                |  |   |                                        |   |  |                                         |            |   |                           |   |            |                             | 
|January 2011 Convertible Notes                         |  |                                        | -          |  |                         |   | 23,989,261 |                                           |  |   | -                            |  |  |                                 | (1,687,500 | ) |                                |   | -           |                                |  |   | (22,301,761                            | ) |  |                                         | -          |   |                           |   | -          |                             | 
|                                                       |  |                                        |            |  |                         |   |            |                                           |  |   |                              |  |  |                                 |            |   |                                |   |             |                                |  |   |                                        |   |  |                                         |            |   |                           |   |            |                             | 
|July 2011 Convertible Notes                            |  |                                        | -          |  |                         |   | 4,950,000  |                                           |  |   | 7,013                        |  |  |                                 | -          |   |                                |   | (1,469,392  | )                              |  |   | (3,480,608                             | ) |  |                                         | (7,013     | ) |                           |   | -          |                             | 
|                                                       |  |                                        |            |  |                         |   |            |                                           |  |   |                              |  |  |                                 |            |   |                                |   |             |                                |  |   |                                        |   |  |                                         |            |   |                           |   |            |                             | 
|July 2011 Series A Convertible Preferred Stock         |  |                                        | -          |  |                         |   | 6,701,000  |                                           |  |   | 9,493                        |  |  |                                 | -          |   |                                |   | (1,989,170  | )                              |  |   | (4,711,830                             | ) |  |                                         | (9,493     | ) |                           |   | -          |                             | 
|                                                       |  |                                        |            |  |                         |   |            |                                           |  |   |                              |  |  |                                 |            |   |                                |   |             |                                |  |   |                                        |   |  |                                         |            |   |                           |   |            |                             | 
|November 2011 Convertible Notes                        |  |                                        | -          |  |                         |   | 4,950,000  |                                           |  |   | 18,069                       |  |  |                                 | -          |   |                                |   | (41,390     | )                              |  |   | -                                      |   |  |                                         | (71        | ) |                           |   | 4,908,610  |                             | 
|                                                       |  |                                        |            |  |                         |   |            |                                           |  |   |                              |  |  |                                 |            |   |                                |   |             |                                |  |   |                                        |   |  |                                         |            |   |                           |   |            |                             | 
|November 2011 Series B Convertible Preferred
    Stock |  |                                        | -          |  |                         |   | 4,024,410  |                                           |  |   | 14,584                       |  |  |                                 | -          |   |                                |   | (68,389     | )                              |  |   | -                                      |   |  |                                         | (79        | ) |                           |   | 3,956,021  |                             | 
|                                                       |  |                                        |            |  |                         |   |            |                                           |  |   |                              |  |  |                                 |            |   |                                |   |             |                                |  |   |                                        |   |  |                                         |            |   |                           |   |            |                             | 
|November 2011 Series C Convertible Preferred
    Stock |  |                                        | -          |  |                         |   | 500,000    |                                           |  |   | 1,833                        |  |  |                                 | -          |   |                                |   | -           |                                |  |   | -                                      |   |  |                                         | -          |   |                           |   | 500,000    |                             | 
|                                                       |  |                                        |            |  |                         |   |            |                                           |  |   |                              |  |  |                                 |            |   |                                |   |             |                                |  |   |                                        |   |  |                                         |            |   |                           |   |            |                             | 
|Total Convertible Debt                                 |  | $                                      | 23,506,858 |  |                         | $ | 56,373,259 |                                           |  | $ | 3,256,121                    |  |  | $                               | (1,687,500 | ) |                                | $ | (30,206,087 | )                              |  | $ | (30,494,199                            | ) |  | $                                       | (2,649,897 | ) |                           | $ | 17,492,331 |                             | 







Activity in connection with the Company’s
convertible debt and preferred stock for the year ended December 31, 2011 is as follows:





Page 71 of 132











|                                                                                  |  | 10% Notes           |          |   | 2010 Notes     |   |             | Senior Notes                |  |   |             |   |  | Legal Settlement         |          |   | Jan’11 |   |            |          | 
|--------------------------------------------------------------------------------- |  | ------------------- | -------- | - | -------------- | - | ----------- | --------------------------- |  | - | ----------- | - |  | ------------------------ | -------- | - | ------ | - | ---------- | -------- | 
|                                                                                  |  | Issued Sept
    '08 |          |   | (all closings) |   |             | (Series 1 and
    Series 2) |  |   | Bridge Note |   |  | A&W Promissory
    Notes |          |   | Notes  |   |            | Subtotal | 
|Carrying Value Before Discount at December 31, 2010                               |  | $                   | 363,942  |   |                | $ | 18,560,993  |                             |  | $ | 4,441,563   |   |  | $                        | 140,360  |   |        | $ | -          |          | 
|Face value of debt issued in 2011                                                 |  |                     | -        |   |                |   | -           |                             |  |   | -           |   |  |                          | -        |   |        |   | 10,771,655 |          | 
|Penalties added to principal                                                      |  |                     | -        |   |                |   | 252,380     |                             |  |   | -           |   |  |                          | -        |   |        |   | 234,553    |          | 
|Payments on debt                                                                  |  |                     | -        |   |                |   | -           |                             |  |   | -           |   |  |                          | -        |   |        |   |            |          | 
|Portion of note converted to equity                                               |  |                     | (317,500 | ) |                |   | (18,813,373 | )                           |  |   | (4,416,563  | ) |  |                          | (140,360 | ) |        |   | (2,949,950 | )        | 
|Exchanged with July 11, 2011 Notes and Series Convertible Preferred
    Stock     |  |                     | -        |   |                |   | -           |                             |  |   | -           |   |  |                          | -        |   |        |   |            |          | 
|Exchanged with November 29, 2011 Notes and
    Series Convertible Preferred Stock |  |                     | -        |   |                |   | -           |                             |  |   | -           |   |  |                          | -        |   |        |   |            |          | 
|Carrying Value Before Discount at December
    31, 2011                           |  |                     | 46,442   |   |                |   | -           |                             |  |   | 25,000      |   |  |                          | -        |   |        |   | 8,056,258  |          | 
|                                                                                  |  |                     |          |   |                |   |             |                             |  |   |             |   |  |                          |          |   |        |   |            |          | 
|Discount, net of accumulated amortization at
    December 31, 2010                |  |                     | -        |   |                |   |             |                             |  |   |             |   |  |                          |          |   |        |   |            |          | 
|Discounts added in 2011                                                           |  |                     | -        |   |                |   | (2,415,650  | )                           |  |   | -           |   |  |                          | -        |   |        |   | -          |          | 
|Amortization expense                                                              |  |                     | -        |   |                |   | 2,415,650   |                             |  |   | -           |   |  |                          | -        |   |        |   | -          |          | 
|Discount, net of accumulated amortization at
    December 31, 2011                |  |                     | -        |   |                |   | -           |                             |  |   | -           |   |  |                          | -        |   |        |   | -          |          | 
|                                                                                  |  |                     |          |   |                |   |             |                             |  |   |             |   |  |                          |          |   |        |   |            |          | 
|Net Carrying Value at December 31, 2011                                           |  | $                   | 46,442   |   |                | $ | -           |                             |  | $ | 25,000      |   |  | $                        | -        |   |        | $ | 8,056,258  |          | 



|                                                                                  |  | Jul’11 |            |     | Jul’11                                   |   |            | Nov’11 |  |   | Nov’11                                       |   |  | Nov’11                                       |            |   |       |  
|--------------------------------------------------------------------------------- |  | ------ | ---------- | --- | ---------------------------------------- | - | ---------- | ------ |  | - | -------------------------------------------- | - |  | -------------------------------------------- | ---------- | - | ----- | -
|                                                                                  |  | Notes  |            |     | Series A Convertible
    Preferred Stock |   |            | Notes  |  |   | Series B
    Convertible
    Preferred Stock |   |  | Series C
    Convertible
    Preferred Stock |            |   | Total |  
|Carrying Value Before Discount at December 31, 2010                               |  | $      | -          |     |                                          | $ | -          |        |  | $ | -                                            |   |  | $                                            | -          |   |       | $
|Face value of debt issued in 2011                                                 |  |        | 4,950,000  |     |                                          |   | 6,701,000  |        |  |   | 4,950,000                                    |   |  |                                              | 4,024,410  |   |       |  
|Penalties added to principal                                                      |  |        | -          |     |                                          |   | -          |        |  |   | -                                            |   |  |                                              | -          |   |       |  
|Payments on debt                                                                  |  |        | -          |     |                                          |   | -          |        |  |   | -                                            |   |  |                                              | -          |   |       |  
|Portion of note converted to equity                                               |  |        | (1,469,392 | )   |                                          |   | (1,989,170 | )      |  |   | (41,390                                      | ) |  |                                              | (68,389    | ) |       |  
|Exchanged with July 11, 2011 Notes and Series Convertible Preferred
    Stock     |  |        | -          |     |                                          |   | -          |        |  |   | -                                            |   |  |                                              | -          |   |       |  
|Exchanged with November 29, 2011 Notes and
    Series Convertible Preferred Stock |  |        | (3,480,608 | )   |                                          |   | (4,711,830 | )      |  |   | -                                            |   |  |                                              | -          |   |       |  
|Carrying Value Before Discount at December
    31, 2011                           |  |        | -          |     |                                          |   | -          |        |  |   | 4,908,610                                    |   |  |                                              | 3,956,021  |   |       |  
|                                                                                  |  |        |            |     |                                          |   |            |        |  |   |                                              |   |  |                                              |            |   |       |  
|Discount, net of accumulated amortization at
    December 31, 2010                |  |        |            |     |                                          |   |            |        |  |   |                                              |   |  |                                              |            |   |       |  
|Discounts added in 2011                                                           |  |        | (4,950,000 | )   |                                          |   | (6,701,000 | )      |  |   | (4,950,000                                   | ) |  |                                              | (4,024,410 | ) |       |  
|Amortization expense                                                              |  |        | 4,950,000  | (1) |                                          |   | 6,701,000  | (2)    |  |   | 465,707                                      |   |  |                                              | 420,059    |   |       |  
|Discount, net of accumulated amortization at
    December 31, 2011                |  |        | -          |     |                                          |   | -          |        |  |   | (4,484,293                                   | ) |  |                                              | (3,604,351 | ) |       |  
|                                                                                  |  |        |            |     |                                          |   |            |        |  |   |                                              |   |  |                                              |            |   |       |  
|Net Carrying Value at December 31, 2011                                           |  | $      | -          |     |                                          | $ | -          |        |  | $ | 424,317                                      |   |  | $                                            | 351,670    |   |       | $









| | (1) | Includes $220,737 recorded as loss on extinguishment in connection
                                                                 with the November 2011 Exchange Transaction.
| | --- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (2) | Includes $298,820 recorded as loss on extinguishment in connection
                                                                 with the November 2011 Exchange Transaction.
| | --- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------





Page 72 of 132







Activity in connection with the Company’s convertible
debt for the year ended December 31, 2010, is as follows:



|                                                                                            |  | 10% Notes   |            |   | St. George
    Debt |   |          | 2010 Notes |  |   |            |  
|------------------------------------------------------------------------------------------- |  | ----------- | ---------- | - | ------------------- | - | -------- | ---------- |  | - | ---------- | -
|                                                                                            |  | Issued Sept |            |   | Issued Sept         |   |          | Issued     |  |   | Issued     |  
|                                                                                            |  | '08         |            |   | '09                 |   |          | 3/22/10    |  |   | 4/8/10     |  
|Carrying Value Before Discount at December 31, 2009                                         |  | $           | 1,624,886  |   |                     | $ | 616,390  |            |  | $ | -          |  
|Face value of debt issued in 2010                                                           |  |             | -          |   |                     |   | -        |            |  |   | 925,000    |  
|                                                                                            |  |             |            |   |                     |   |          |            |  |   |            |  
|Additional penalities for trigger events and forbearance fees added
    to the note balance |  |             | 169,904    |   |                     |   | 50,000   |            |  |   | 1,410,422  |  
|                                                                                            |  |             |            |   |                     |   |          |            |  |   |            |  
|Portion of note converted to equity                                                         |  |             | (1,430,848 | ) |                     |   | (666,390 | )          |  |   | (1,862,485 | )
|Carrying Value Before Discount at December 31, 2010                                         |  |             | 363,942    |   |                     |   | -        |            |  |   | 472,937    |  
|                                                                                            |  |             |            |   |                     |   |          |            |  |   |            |  
|Discount, net of accumulated amortization at
    December 31, 2009                          |  |             | (1,607,111 | ) |                     |   | (393,681 | )          |  |   | -          |  
|Acceleration of amortization in connection with conversion and debt
    extinguishment      |  |             | 1,519,220  |   |                     |   | 393,681  |            |  |   | 261,685    |  
|                                                                                            |  |             |            |   |                     |   |          |            |  |   |            |  
|Discount attributable to 2010 notes                                                         |  |             | -          |   |                     |   | -        |            |  |   | (651,165   | )
|                                                                                            |  |             |            |   |                     |   |          |            |  |   |            |  
|Amortization expense                                                                        |  |             | 87,891     |   |                     |   | -        |            |  |   | 389,480    |  
|Discount, net of accumulated amortization at
    December 31, 2010                          |  |             | -          |   |                     |   | -        |            |  |   | -          |  
|                                                                                            |  |             |            |   |                     |   |          |            |  |   |            |  
|Net Carrying Value at December 31, 2010                                                     |  | $           | 363,942    |   |                     | $ | -        |            |  | $ | 472,937    |  



Page 73 of 132







Activity in connection with the Company’s Senior Debt
during the year ended December 31, 2010, is as follows:



|                                                                |  | Series 1 |           |   | Series 2 |   |          |        | 
|--------------------------------------------------------------- |  | -------- | --------- | - | -------- | - | -------- | ------ | 
|                                                                |  | Dec-08   |           |   | Jan-09   |   |          | May-09 | 
|Carrying Value Before Discount at December 31, 2009             |  | $        | 1,077,500 |   |          | $ | 680,000  |        | 
|Note increase for debt extinguishment                           |  |          | 269,372   |   |          |   | 170,000  |        | 
|Carrying Value Before Discount at December 31, 2010             |  |          | 1,346,872 |   |          |   | 850,000  |        | 
|                                                                |  |          |           |   |          |   |          |        | 
|Discount, net of accumulated amortization, at December 31, 2009 |  |          | (318,178  | ) |          |   | (327,809 | )      | 
|Amortization expense for year ended December 31, 2010           |  |          | 318,178   |   |          |   | 327,809  |        | 
|Discount, net of accumulated amortization, at December 31, 2010 |  |          | -         |   |          |   | -        |        | 
|                                                                |  |          |           |   |          |   |          |        | 
|Net Carrying Value at December 31, 2010                         |  | $        | 1,346,872 |   |          | $ | 850,000  |        | 



Convertible Debt



September - 2008 Convertible Notes



In September 2008, the Company issued
$2,510,000 of Convertible Debt securities (the “2008 Convertible Debt”). The 2008 Convertible Debt originally bore
an interest rate of 10%, and was due in September 2010 or upon a change in control of the Company or certain other events of default,
as defined. However, if the 2008 Convertible Debt had not been converted to common stock at the maturity date, the holder would
be entitled to receive bonus interest equal to 50% of the face value of the note, in addition to the coupon rate of interest.
The 2008 Convertible Debt is unsecured.



Pursuant to a Letter Agreement dated September
24, 2010, the Company sought the remaining 2008 Convertible Debt holders’ agreement to waive the current default and allow
the Company until November 15, 2010 to issue them the shares underlying the 2008 Convertible Debt. In consideration for waiving
the default and extending the maturity date to November 15, 2010, we increased the principal balance of the 2008 Convertible Debt
outstanding as of September 14, 2010 by $56,635 or 25% of the outstanding balance on September 14, 2010 (the “25% Increase”)
and increased the interest rate to 18%, which rate applies to the interest due from September 15, 2010 until the Debt is converted
pursuant to the 2008 Letter Agreement. The 2008 Convertible Debt holders were entitled to the Bonus Interest, which was calculated
as a one-time fee of $113,269 or 50% of the outstanding principal balance on September 14, 2010. The amount of the 25% Increase
and Bonus Interest was combined and directly applied to the principal amount of the Debts outstanding on September 14, 2010. The
outstanding balance of the 2008 Convertible Debt immediately before the 2008 Letter Agreement was $226,538. Finally, we agreed
to adjust the Conversion Price of the 2008 Convertible Debt to equal 80% of the VWAP for the 5 trading days immediately preceding
the date we receive NYSE Amex approval of the additional shares to be issued pursuant to the adjusted price (the “Adjusted
Shares”); provided however, that in no event shall the Conversion Price be less than $7.00 per share.



Since we did not issue the shares on November
15, 2010, because the SEC comment period prevented us from holding a shareholder meeting to obtain the related approval for such
issuance on November 15, 2010, the outstanding 2008 Convertible Debt are susceptible to default. As of the filing date, we have
not received any default notices.



During the year ended December 31, 2011,
note holders converted $317,500 of principal and $53,555 of interest, representing 87% of the outstanding balance of the note
balance as of December 31, 2010. The Company issued 19,068 shares of its common stock upon the conversion of the notes.



As of December 31, 2011, the principal
amount of $46,442 was outstanding on the 2008 Convertible Debt, with a combined accrued interest of $16,081, all of which is convertible
into shares of our common stock pursuant to the Letter Agreement described above.



Page 74 of 132







2010 Note and Warrant Purchase Agreements



During year ended December 31, 2010, the
Company completed four closings of convertible note and warrant purchase agreements (“Purchase Agreements”), aggregating
to approximately $11 million. The convertible notes issued in the four 2010 Closings, (collectively “2010 Notes”)
matured one year from the date of their respective issuance and carried al 20% original issuance discount. The Purchase Agreement
for the First closing included a five-year warrant to purchase 44,000 shares of the Company’s common stock at an exercise
price equal to the higher of: (i) 105% of the VWAP for the five trading days immediately preceding the date the Company issued
the Warrants; or (ii) the Floor Price (as defined in the First Closing Note). The Purchase Agreements for the Second, Third, and
Fourth closings included a five-year warrant to purchase up to 481,947 shares of the Company’s common stock at initial exercise
prices ranging from $7.00 to $22.25 per share. The 2010 Notes were convertible, in whole or in part, into shares of the Company’s
common stock. The Conversion Price was equal to the greater of the Floor Price (as defined in the Notes) or 80% of the VWAP for
the five (5) Trading Days ending on the business day immediately preceding the applicable date of conversion.



The embedded conversion feature of the
2010 Notes and related warrants were recorded as derivative liabilities in accordance with relevant accounting guidance due to
the down-round protection of the conversion price of the 2010 Notes and the exercise price of the Warrants. The Company originally
recorded a debt discount of $10,783,530, representing the value of the embedded conversion feature and warrants. The debt discount
was being amortized on a straight-line method over the terms of the debt, which approximated the effective-interest method. During
the year ended December 31, 2011, the Company recorded $2,415,650 of amortization of the debt discount, which included $242,090
in accelerated amortization due to the conversions. The balance of the debt discount at December 31, 2011 was $0.



The Company also incurred debt issuance
costs totaling $821,300 in association with the 2010 Notes. Those costs are included in other assets in the condensed consolidated
balance sheet at December 31, 2010, and are being amortized over the life of the debt using the effective interest method. During
year ended December 31, 2011, the Company recorded $170,826 of amortization of the debt issuance costs. The balance of the debt
issuance costs at December 31, 2011 was $0.



Interest on the unpaid principal balance
of the 2010 Notes originally accrued at the rate of 12% per annum, which would increase to 18% upon the occurrence of a trigger
event, as that term is defined in the 2010 Notes. Pursuant to the terms of the First, Second, and Third Closings, a trigger event
occurred when the Registration Statement the Company filed on May 3, 2010 was not declared effective by June 1, 2010 and therefore
the interest on the notes issued in those three closings increased to 18% per annum. The terms of the Fourth closing required
the Company to have the registration statement declared effective by August 31, 2010 and therefore a Trigger Event occurred when
the Registration Statement the Company filed on May 3, 2010 was not declared effective by August 31, 2010 with respect to the
notes issued in the Fourth Closing.



As a result of the Trigger Events, the
principal amount of the 2010 Notes was increased from $11,057,365 to $14,081,712. In addition, pursuant to the terms of the Registration
Rights Agreement, the Company recorded an additional $410,000 as interest expense which represents the maximum amount of $10,000
payable to each convertible note holder in the four closings due to failure to obtain effectiveness of registration statement.



Additionally, we were required under the
terms of the 2010 Notes to obtain stockholder approval, on or before July 15, 2010 for the First Closing and on or before August
31, 2010, for the Second, Third, and Fourth Closings. Due to the SEC review of our proxy statement and periodic reports that we
are required to submit to our shareholders with the Proxy Statement, we were unable to file and mail our definitive proxy statement
so as to give our shareholders proper notice of an August 31, 2010 meeting and therefore were not able to have a meeting or obtain
shareholder approval on such date. This failure constituted an Event of Default under the 2010 Notes, pursuant to which the note
holders were entitled to declare the entire principal and interest due on the notes then immediately payable. In light of the
default, to maintain good relationships with the investors of the 2010 Notes, we requested the 2010 Notes’ investors to
waive the July 15, 2010 and August 31, 2010 shareholder meeting date requirement and instead allow us to hold the meeting on or
before November 15, 2010, as well as waive any defaults related thereto, in exchange for which we increased the balance of the
notes by 25% (the “Extension”). As a result of the 25% increase from the Extension, the principal amount of such notes
was increased to $18,872,264.



Page 75 of 132







On October 14, 2010, the Company entered
into a forbearance agreement (“Forbearance Agreement”) with two investors (ISP Holdings, LLC and St. George Investments,
LLC) of the 2010 Notes. These investors negotiated the terms of the Forbearance Agreement in lieu of entering into the Extension
the other 2010 Notes investors signed. Pursuant to the Forbearance Agreement, the two investors refrained and temporarily forbore
from exercising and enforcing their remedies against the Company due to the Event of Default and in return the Company agreed
as a compensation for damages to the two investors to increase the outstanding balance of the 2010 Notes to ISP Holdings, LLC
by 68% and increase the outstanding balance of the 2010 Notes to St. George Investments, LLC by 25%. In addition, the Company
agreed to obtain the required Shareholder Approval to issue the shares underlying the 2010 Notes and warrants on or before November
15, 2010. In relation to this agreement, the Company recorded $381,920 in additional principal, and offsetting interest expense,
for the liquidation damages of the warrants and $300,773 as a loss on extinguishment of debt and is reflected in other expenses,
net, in the accompanying condensed consolidated statements of operations. Since we did not hold the meeting by November 15, 2010
(due to the SEC comment period), these two note holders submitted notice to us that the balance of their note shall increase by
another 25% under the terms of the Forbearance Agreement. As of December 31, 2010, we increased the outstanding note balance of
these two note holders by $868,522 for the 25% that was contractually due, but were under negotiations. Since we had not entered
into any settlement, on May 26, 2011, these two note holders submitted default notices to us demanding payment of the note in
full, including principal, interest, penalties and legal fees, accrued up to June 1, 2011 for an aggregate total of $1,306,619.
On June 6, 2011, an agreement was reached with these note holders and an aggregate total of additional penalties in the amount
of $94,297 were added to the principal of their notes.



In April 2011, the Company entered into
a Debt Exchange Agreement whereby the outstanding balance of one of the Convertible Notes, including premiums, was exchanged for
shares of the Company’s common stock. As part of this exchange, the note holder of the 2010 Note converted $479,806 of principal
and $92,967 of accrued interest, premiums of $121,494 and legal fees of $5,000 into 73,993 shares of the Company’s common
stock. The premium was recorded as extinguishment of debt.



On August 3, 2011, the Company received
from one investor (St. George Investments, LLC) of the 2010 closings a Notice of conversion to convert $200,000 into 180,832 shares
of common stock. At that time, the Company had insufficient authorized number of shares available for issuance. On August 19,
2010, the Company increased its number of authorized shares, and on August 25, 2011, issued the shares due under the conversion.



On August 18, 2010, the Company received
a forbearance agreement (“Forbearance Agreement”) from the investor, as a proposal of settling the delay in the issuance
of the shares in accordance with the conversion terms. The Company, its legal advisers and the investor entered in several discussions
which resulted in the investor agreeing to temporarily forbear from exercising and enforcing their remedies against the Company
due to the event of default and, in return, the Company agreed to the following compensation for damages.



On August 22, 2011, the Company did not
execute the Forbearance Agreement, but acknowledged by e-mail the terms stipulated in the agreement the conversion mechanisms
of the penalties included in the Forbearance Agreement. This is considered the date of effectiveness of the Forbearance Agreement.



As a result of the penalty, the Company
increased the debt balance by $158,082, and recorded such amount in interest expense in the accompanying consolidated statement
of operations for the year ended December 31, 2011. Also, the Company recorded the fair value of the embedded conversion feature
of the debt as additional interest expense for penalties added with a corresponding increase to derivative liability on August
22, 2011 (the date both parties agreed to the proposed penalties). Since the terms of the debt did not change, there was no debt
discount associated with this transaction.



On September 29, 2011, one note holder
submitted a conversion exercise notice form for $70,000 which was convertible into 1,206,897 shares of common stock. The Company
could not process the conversion, due to insufficient authorized shares of common stock, and issued the shares on December 20,
2011.



During the year ended December 31, 2011,
as detailed in the table above, a total of $18,813,373 of principal and $1,398,776 of accrued interest of this debt was converted
into 5,742,136 shares of the Company’s common stock. As of December 31, 2011, the entire principal of the 2010 Notes was
converted, and $321,958 of accrued interest is outstanding.



Page 76 of 132







Convertible Senior Notes



Series 1



In December 2008, in the first closing
of the 12% Senior Note offering, the Company issued units consisting of $1,077,500 principal amount of 12% Senior Promissory Notes
(“Series 1 Senior Notes”) and five-year warrants to purchase a total of 34,480 shares of the Company’s common
stock at $25.00 per share. On January 30, 2009, the Company conducted the second and final closing of the Series 1 Senior Note
offering whereby the Company sold an additional $680,000 principal amount of Senior Notes and a five-year warrant to purchase
a total of 21,760 shares of common stock at $28.25 per share. Accordingly, a total of $1,757,500 in Senior Notes and Warrants
to purchase 56,240 shares of common stock in the Senior Note Offering were sold in 2008 and 2009. The Senior Notes originally
bore an interest rate of 12% per annum, payable semi-annually on June 1st and December 1st of each year after issuance. The Senior
Notes matured on the earlier of the second anniversary of the closing date or upon the completion of the closing of a credit facility
or loans by the Company or its subsidiaries with a financial institution or bank of not less than $8 million in a transaction
or series of transactions. The Senior Notes are unsecured, and are senior to the other Convertible Debt. The Company was not permitted
to issue additional notes or evidence of indebtedness that are senior in priority to the Senior Notes, however, the Company was
permitted to issue notes up to an aggregate principal amount of $2,500,000 which were of equal priority with the Senior Notes.
In September 2010, as a result of the September 2010 Amendment to the Debt Exchange agreement (discussed below), the Company increased
the principal of these notes by $439,372. The total principal of the Series 1 Senior Notes at December 31, 2010 was $2,196,875
and $526,325 of accrued interest.



On January 3, 2011, the shares underlying
the Exchange Agreement with the Senior Note holders were approved by the NYSE Amex and these notes became convertible into the
Company’s common stock.



During the year ended December 31, 2011,
note holders converted $2,196,875 of principal and $552,328 of interest. The Company issued 237,261 shares of its common stock
upon the conversion of the notes. As of December 31, 2011, the entire principal and interest accrued of the Senior Note was converted.



Series 2



On May 4, 2009, the Company conducted
a first closing of a private offering under Regulation D for the sale to accredited investors of units consisting of $1,327,250
principal amount of Series 2 Senior Notes and five-year warrants to purchase a total of 84,944 shares of the Company’s common
stock at $24.50 per share (the “Warrant Shares”). On June 12, 2009, the Company conducted the second closing of a
private offering under Regulation D for the sale to accredited investors of units consisting of $468,500 principal amount of Series
2 Senior Notes (“Series 2 Senior Notes”) and five-year warrants to purchase a total of 29,984 shares of the Company’s
common stock at $27.75 per share (the “Warrant Shares”). Under the terms of the offering, the exercise price of the
Warrant Shares was 115% of the five (5) day volume weighted average closing price of the Company’s common stock on NYSE
Amex for the five (5) trading days prior to the date of the closing. In September 2010, as a result of the September 2010 Amendment
to the Debt Exchange agreement (discussed below), the Company increased the principal of this note by $448,941. The total principal
of these notes at December 31, 2010 was $2,244,688 and accrued interest was $457,769.



In April 2011, the Company entered into
a series of Debt Exchange Agreements whereby the outstanding balances of several of the Convertible Notes, including premiums,
were exchanged for shares of the Company’s common stock. Holders of the Series 2 Senior Notes converted $600,000 of principal
and $115,368 of accrued interest, premiums of $87,781 and legal fees of $10,000 into 108,344 shares of the Company’s common
stock. The premiums were recorded as an extinguishment of debt.



During the year ended December 31, 2011,
note holders converted $2,219,688 of principal and $603,108 of interest, representing 99% of the outstanding balance of these
notes. The Company issued 314,106 shares of its common stock upon the conversion of the Series 2 Senior Notes. The balance of
the Series 2 Senior Notes as of December 31, 2011 was $25,000 in principal and $9,598 of accrued interest.



Page 77 of 132







Exchange Agreement



The Company did not make the required
interest payments on the Series 1 Senior Notes or the Series 2 Senior Notes (collectively “the Senior Notes”) due
on December 1, 2009 or March 1, 2010. The Company did not have sufficient cash to satisfy these Notes and carry on current operations.
Consequently, under the terms of the Series 1 and 2 Senior Notes, the interest rate increased from 12% to 18% per annum. The failure
to pay interest as scheduled represented an Event of Default under the terms of the Series1 and 2 Senior Notes and all senior
debt was classified as current. However, none of the holders declared default, or declared the outstanding Senior Notes and other
contractual obligations immediately due.



In order to resolve the defaults and to
preserve as much cash as possible for operations, management put together an exchange agreement (the “Debt Exchange”)
to enter into with its the debt holders, subject to shareholder approval (“Shareholder Approval”) of such share issuances,
pursuant to which the debt holders would exchange their outstanding Senior Notes or other debt obligations for shares of the Company’s
common stock. Some of the key provisions of the Debt Exchange agreement were as follows:



First, all of the issuances pursuant to
the proposed Debt Exchanges were subject to Shareholder Approval. The Company obtained the required Stockholder Approval by November
10, 2010. Based on the terms of the various exchange and/or extension/wavier agreements, all of the Senior Notes would fall back
into default, pursuant to which the note holders could declare the full amount owed on the Senior Notes immediately due and payable,
if the Company failed to hold the meeting by the required dates. Once the Company obtained Shareholder Approval to issue the shares
pursuant to a particular Debt Exchange, upon such issuance, the debt related to such exchange agreement would be convertible into
shares of common stock and the holders thereof would waive all current and future defaults under the debt.



Second, the Company agreed to use its
best efforts to register the shares issuable pursuant to the exchange agreements in the next registration statement to be filed
under the Securities Act of 1933, as amended.



Third, the issuance of all of the shares
of common stock to be issued under these Debt Exchanges was subject to NYSE Amex listing approval.



Under the terms of the Debt Exchange agreement,
the Senior Notes would become convertible once all items above were met. The number of shares of common stock issuable to the
note holder upon conversion was an amount equal to the quotient of: the amount of principal sought to be exchanged divided by
seventy percent (70%) of the VWAP for the five (5) trading days immediately preceding the date of the exchange request; provided
however, in no event shall the exchange price be less than $7.00.



In September 2010, the Company amended
the Debt Exchange Agreement (“September 2010 Amendment to Debt Exchange Agreement”) with the Series 1 and 2 Note Holders.
Pursuant to the September 2010 Amendment to Debt Exchange Agreement, the Series 1 and 2 Senior Note Holders agreed to extend the
date of the required shareholder meeting to a date on or before November 15, 2010 instead of September 15, 2010. In return, the
Company agreed to (a) increase the principal balance due on the Senior Notes by 25% effective September 1, 2010 and (b) the Company
in its - sole discretion — maintains the right to pay the interest due on the Senior Notes in shares of its common stock
so long as the market price of the Company’s common stock is equal to or above $0.28 per share on the date such interest
is due. Due to the SEC’s review of the periodic reports that we were required to mail with the proxy statement, seeking
the Stockholder Approval, we were unable to hold the related meeting until December 3, 2010. Our stockholders approved all of
the shares underlying the Debt Exchange Agreement at the December 3, 2010 meeting and the NYSE Amex approved the shares on January
3, 2011. All of the consideration granted to the note holders pursuant to the exchange and/or extension/waiver agreements remained
in effect and no other consideration was owed to the note holders pursuant to this default. The total for the additional penalty
was $888,275 and was included in loss on extinguishment of debt for the year ended December 31, 2010 Any shares of common stock
to be issued pursuant to the Debt Exchange will be issued pursuant to Section 4(2) of the Securities Act for issuances not involving
a public offering and Regulation D promulgated hereunder.



On January 3, 2011 when the NYSE Amex
approved the listing of the shares, all conditions of the exchange were satisfied and the Series 1 and 2 Senior Notes were exchanged
for Senior Convertible Notes (as all of the shares underlying the Debt Exchange Agreement are eligible for resale pursuant to
Rule 144 as promulgated under the Securities Act of 1933, as amended, we requested all of the outstanding Series 1 and Series
2 Note holders to waive the registration requirement). As a result of the Debt Exchange agreement the Senior Notes were considered
extinguished and new Senior Convertible Notes issued. In accordance with relevant accounting guidance, the Company determined
the new Senior Convertible Notes contained a beneficial conversion feature. The Company recorded $4,441,563 as the fair value
of the beneficial conversion feature to additional paid-in capital and loss on extinguishment.



Page 78 of 132







As of December 31, 2011, principal and
interest in the amount of approximately $5,571,999, representing 99% of the Senior Convertible Notes have been converted into
551,367 shares of the Company’s common stock (see above).



Activity in connection with the Company’s
Senior Convertible Notes during the year ended December 31, 2011, is as follows:



|                                    |  | Series 1 |            |   | Series 2 |   |          |        | 
|----------------------------------- |  | -------- | ---------- | - | -------- | - | -------- | ------ | 
|                                    |  | Dec-08   |            |   | Jan-09   |   |          | May-09 | 
|Carrying Value at December 31, 2010 |  | $        | 1,346,875  |   |          | $ | 850,000  |        | 
|Principal converted                 |  |          | (1,346,875 | ) |          |   | (850,000 | )      | 
|Carrying Value at December 31, 2011 |  | $        | -          |   |          | $ | -        |        | 



The Bridge Loan Agreement



On September 10, 2009, the Company entered
into a Bridge Loan Agreement (the “Bridge Loan Agreement”) with Cantone Research, Inc. (the “Lender”)
whereby the Lender agreed to provide a Bridge Loan for $58,000 (the “Bridge Loan”) and the Company agreed that the
proceeds of the Bridge Loan would be used exclusively to pay interest due on currently outstanding “Senior Notes”.
Interest under the Bridge Loan was set at 12% per annum. However, because the Company did not repay the Bridge Loan as scheduled
on or before October 9, 2009, the interest rate was increased to 18% per annum, retroactive to September 10, 2009. Since the Bridge
Loan was not repaid by December 1, 2009, $25,000 was added to the principal value of the Bridge Loan obligation, making the current
principle value of the Bridge Loan $83,000 as of December 31, 2009. Pursuant to the Bridge Loan Agreement, against receipt of
the Bridge Loan, the Company issued to the Lender a two-year warrant to purchase 4,640 shares of the Company’s common stock
exercisable at $15.00 per share (the “Two-Year Warrant”). This warrant was valued at $34,800 using the Black-Scholes
model with a discount rate of 0.93% and a volatility of 0.9308% on the date of the Bridge Loan Agreement. Under the appropriate
accounting guidance, the Company recorded the value of the warrant at its relative fair value as a debt discount which was amortized
to interest expense over the term of the bridge loan. The Company paid cash fees associated with this debt of $15,000, which was
recorded as debt issuance costs. The Company recorded interest expense of approximately $49,800 related to the debt issuance costs
as of December 31, 2010.



In March 2010, the Company entered into
an Exchange Agreement with the Lender. Under the Exchange Agreement, we agreed to the issuance of up to an aggregate of 404,526
shares of our common stock, issuable upon: (i) exchange and cancellation of all principal amount of the Bridge Loan; (ii) cancellation
of all of the interest accrued thereon, accruing at the contractual default rate of 18%, retroactively from September 10, 2009
through August 30, 2010; (iii) cancellation of all other fees due under the Bridge Loan, totaling approximately $12,000 and (iv)
in consideration for such exchange and cancellations, a reduction of the warrant exercise price for the 4,640 warrants originally
issued in connection with the Bridge Loan from $15.00 per share to $7.00 per share.



Pursuant to the Bridge Loan Exchange Agreement,
we were required to obtain shareholder approval by September 15, 2010. Since our failure to obtain shareholder approval by September
15, 2010 would subject us to being in default of the Bridge Loan, on September 13, 2010, we sought the Bridge Loan holder’s
agreement to instead hold the meeting on or before November 15, 2010. In consideration for their agreement to extend the time
in which we were to obtain shareholder approval, and waive any defaults related to our failure to hold the meeting by September
15, 2010, we agreed to increase the principal balance of the Bridge Loan by 25% and pay an additional $5,000 in legal fees related
to the default. In accordance with relevant accounting guidance, the Company recorded the 25% increase of $57,360 to the principal
balance as a loss on extinguishment.



On September 14, 2010, the Company recorded
a beneficial conversion feature of the principal balance of the note, which resulted in the recording of $140,360 as debt discount
and amortization expense of $140,360 through December 31, 2010. As a result of this agreement, we agreed to issue the holder 23,690
shares instead of 16,181, which include interest payments due through December 31, 2010. The issuance of shares pursuant to the
amendment was subject to our receipt of NYSE Amex listing approval and Shareholder Approval. If we did not receive Shareholder
Approval, the exercise price of the warrants would remain at their pre-agreement amounts and the Company will have to pay the
principal and accrued interest in cash. The Shareholder Approval was received on December 3, 2010 and the NYSE Amex listing approval
was received on January 3, 2011.



Page 79 of 132







As of December 31, 2010, the principal
of the Bridge Loan was $140,360 and related accrued interest was $25,474.



During the year ended December 31, 2011,
aggregated principal and interest in the amount of $165,834 was converted into 23,690 shares of the Company’s common stock.



2011 Notes



On January 30, 2011, the Company entered
into a securities purchase agreement with five accredited investors (“Investors”) in a private equity financing of
$8,437,500 and received approximately $7,500,000 in gross proceeds from the sale of convertible notes pursuant to the securities
purchase agreement. Net proceeds from the financing were approximately $6,820,000. In connection with the closing of the transactions,
the Company issued Convertible Promissory Notes in the aggregate principal amount of $8,437,500 (the “January 2011 Notes”),
at a purchase price of $888.88 for each $1,000 of principal amount of notes, which are initially convertible into an aggregate
of 562,500 shares of the Company’s common stock (“2011 Note Shares”) to the Investors. The Investors also received:
(i) Series A Warrants (“Series A Warrants”) to purchase an aggregate of 562,500 shares of our common stock (“Series
A Warrant Shares”) at an initial exercise price of $16.75 per share and (ii) Series B Warrants (“Series B Warrants,”
together with the Series A Warrant, the “Warrants”) to purchase an aggregate of 281,250 shares of our common stock
(the “Series B Warrant Shares,” together with the Series A Warrant Shares, the “Warrant Shares”) at an
initial exercise price of $20.44 per share for their investment. Each of the Warrants has a term of five (5) years from the date
the Warrants are initially exercisable.



Pursuant to the terms of the securities
purchase agreement, the Company was required to have a shareholder meeting no later than April 30, 2011 seeking shareholder approval
for (a) the issuance of all January 2011 Note Shares and Warrant Shares without any restrictions or limitations pursuant to the
NYSE Amex and (b) an increase in the Company’s authorized shares of common stock to 20,000,000 (“Shareholder Approval”).
Prior to obtaining Shareholder Approval the Company is required to reserve that number of shares of its common stock which represents
100% of the January 2011 Shares and the Series A Warrant Shares; after obtaining Shareholder Approval, the Company is required
to reserve that number of shares of its common stock which represents 130% of the shares of common stock issuable upon conversion
of the January 2011 Notes and exercise of the Warrants. Failure to obtain Shareholder Approval by the required dates constitutes
an event of default under the January 2011 Notes. Due to our inability to file our proxy statement we were unable to hold the
required shareholders meeting.



Pursuant to the securities purchase agreement
and January 2011 Notes, for so long as any January 2011 Notes or Warrants remain outstanding, the Company cannot issue or sell
any rights, warrants or options to subscribe for or purchase shares of its common stock or directly or indirectly convertible
into or exchangeable or exercisable for shares of its common stock at a price which varies or may vary with the market price of
its common stock, including by way of one or more reset(s) to any fixed price unless the conversion, exchange or exercise price
of any such security cannot be less than the then applicable conversion price of the January 2011 Notes or the then applicable
exercise price of the Warrants. For so long as any January 2011 Notes or Warrants are outstanding, unless or until the Company
has received Shareholder Approval, the Company shall not take any action if the effect of such action would be to cause the exercise
price of the Warrants or the conversion price of the January 2011 Notes to be reduced or to cause the number of January 2011 Note
Shares or Warrant Shares to be increased. For so long as any January 2011 Notes are outstanding, neither the Company nor our subsidiaries
shall incur any debt, other than trade payables incurred in the ordinary course of business consistent with past practice, certain
unsecured indebtedness incurred by the Company that is made expressly subordinate to the January 2011 Notes, and in connection
with certain scheduled transactions contemplated by our subsidiaries.



The January 2011 Notes mature on December
1, 2011 and are convertible at any time at the Investors’ option; however the January 2011 Notes cannot be converted if
such conversion would result in a Investor beneficially owning more than 4.99% of the Company’s outstanding common stock.
The Company is required to pay a certain portion of the January 2011 Note (“Installment Amount”) back on the first
day of each month during the term of the January 2011 Note, beginning on March 1, 2011, and the Company has the option to pay
the Installment Amount in shares of its common stock, if certain conditions as set forth in the January 2011 Notes are met, in
cash or in any combination of shares of its common stock and cash. The Installment Amount for each January 2011 Notes is equal
to the lesser of (A) the product of (i) $843,750 multiplied by (ii) a Investors’ pro rata portion of all of the January
2011 Notes sold pursuant to the financing and (B) the outstanding principal amount under such Investors’ January 2011 Note
as of such payment date. If the Company elects to pay any portion of the Installment Amount in cash, it has to pay an amount in
cash equal to 100% of the applicable redemption amount; if the Company fails to do so, the Investor has the right to require the
Company to convert all or any portion of such amount owed into shares of common stock at the then current conversion price. If
the Company elects to pay any portion of the Installment Amount in shares of common stock, then the Company is required to issue
such number of shares of its common stock equal to the quotient of the formula set forth in the January 2011 Notes. Upon the occurrence
of an Event of Default under the January 2011 Note, a or a Change of Control – as that term is defined in the January 2011
Notes, the Investor has the right to force the Company to redeem all or any portion of such Investors’ January 2011 Notes
in cash at a price equal to 125% of the greater of (x) the amount of the January 2011 Note sought to be redeemed and (y) the product
of (A) the quotient of the amount sought to be redeemed divided by the then current conversion price and (B) the greatest closing
sale price of our common stock on any trading day during the period beginning on the date immediately preceding (y) in the event
of an event of default, such event of default, or (x) in the event of Change of Control, the earlier to occur of (1) the consummation
of the Change of Control and (2) the public announcement of such Change of Control, and ending on the date the Investor delivers
redemption notice.



Page 80 of 132







The Warrants are initially exercisable
upon the earlier of: (i) the six month anniversary after the closing of the financing, (ii) the date that the Company’s
common stock ceases to be listed or quoted on the NYSE Amex and (ii) the date that the Company obtains Shareholder Approval. At
any time following nine months after the closing, if the Company’s stock price is at or above 200% of the initial exercise
price of a Warrant and certain other conditions are met, the Company can force the Buyers to exercise up to 50% of the then unexercised
portion of that Warrant. The Warrants cannot be exercised if such exercise would result in a Buyer beneficially owning more than
4.99% of the Company’s outstanding common stock.



The conversion price of the January 2011
Notes and exercise price of the Warrants are each subject to adjustment if the Company issues additional shares of its common
stock or securities convertible or exercisable into shares of its common stock at a price below the conversion price or exercise
price, respectively, as well as upon subdivision or combination of its common stock and other events similar to the aforementioned
events. Upon any anti-dilution adjustment of the exercise price of the Warrants, the number of Warrant Shares issuable upon exercise
of such Warrants will be proportionately increased. The exercise price of the Warrants is also subject to further adjustment pursuant
to other specified events in the Warrant. The warrants may be exercised on a cashless basis as long as a registration statement
is not declared effective. The number of net shares issuable upon a cashless exercise is calculated as follows: (A x B) –
(A x C) /D where A) is the number of warrants being exercise, B) is the WAP of the common stock on the day preceding the date
of exercise, C) is the warrant exercise price, and D) is the common stock closing price on the date of exercise.



The January 2011 Notes contain certain
covenants which include a cash reserve covenant whereby the Company shall maintain in its bank accounts no less than $2,250,000
in unrestricted cash at all times. In addition, the January 2011 Notes agreement restricts the use of proceeds to pay any other
debt obligations.



The Company also entered into a Registration
Rights Agreement with the Investors pursuant to which it was required to file the registration statement by February 9, 2011 providing
for the resale of 130% of the shares of common stock issuable upon conversion of the January 2011 Notes and exercise of the Warrants,
although certain exceptions to the amount required to be registered at any one time as a result of certain securities laws are
contained in the registration rights agreement. The Company was also required to have the registration statement declared effective
within 60 days after the closing of this financing (or 90 days if there is a full review by the Securities and Exchange Commission).
We were also required to keep the registration effective at all times until the earlier of (i) the date as of which the Investors
may sell all of the January 2011 Note Shares and Warrant Shares without restriction or limitation pursuant to Rule 144 of the
Securities Act of 1933, as amended and without the requirement to be in compliance with Rule 144(c)(1) (or any successor thereto)
promulgated thereunder or (ii) the date on which the Investors shall have sold all of the January 2011 Note Shares and Warrant
Shares required to be registered under the Registration Rights Agreement. If the Company failed to file the registration statement
by the required date, have it effective by the required date or maintain the effectiveness as required, that the Company shall
be required to pay to the Investors an amount in cash equal to 1.5% of the purchase price for the January 2011 Note Shares and
Warrant Shares included in the applicable registration statement. Such amount shall be due on the date of such failure and every
30 days thereafter for which the failure is not cured and if the payments are not made on time, they shall bear interest at the
rate of 1.5% per month. The registration statement was filed on February 9, 2011. On March 10, 2011, the Company received notice
from the SEC that it did not meet the eligibility requirements for the S-3 filing to register the shares on such form and therefore
must seek to register the shares on Form S-1. As of April 1, 2011, the registration statement was not effective and the Company
paid in cash $126,563 of additional interest for the registration penalty. The Company accrued an additional registration penalty
of $253,125 for May and June 2011.



Page 81 of 132









The embedded conversion feature of the
January 2011 Notes and Warrants was recorded as derivative liabilities in accordance with relevant accounting guidance due to the
down-round protection of the conversion price of the January 2011 Notes and the exercise price of the Warrants. In addition, the
Company issued five-year warrants to purchase 33,582 shares of the Company’s common stock exercisable at $16.75 per share
to placement agents in association with the January 2011 Notes. The fair value on the grant date of the embedded conversion feature
of the convertible debt and warrants amounted to $4,994,441 and $11,144,007 respectively, as computed using the Binomial Lattice
option pricing model.



The Company established a debt discount
of $8,437,500, representing the value of the embedded conversion feature inherent in the convertible debt, as limited to the face
amount of the debt. The debt discount is being amortized over the life of the debt using the straight-line method over the terms
of the debt, which approximates the effective-interest method. Due to the default event in May 2011, the notes became due and payable
at that time and the amortization of the debt discount was accelerated. For the year ended December 31, 2011, the Company recorded
amortization of the debt discount of $8,437,500. The balance of the debt discount was $0 at December 31, 2011.



The Company also incurred debt issuance
costs of $680,000, which were deducted from the net proceeds. In addition, the fair value of the placement agent warrants was recorded
as a debt issuance cost in the amount of $386,194. These costs were being amortized over the life of the debt using the straight-line
method, which approximates the effective interest method. Due to the default event in May 2011, the notes became due and payable
at that time and the amortization of the debt issuance costs was accelerated. During the year ended December 31, 2011, $1,066,195
was amortized as interest expense. The balance of the debt discount was $0 at December 31, 2011.



On March 1, 2011 and April 1, 2011, the
Company made the first two installments due of $843,750 each. On May 3, 2011, the Company failed to make the third installment
on the January 2011 Notes and an event of default occurred. As a result, all of the five investors submitted an Event of Default
Redemption Notice to the Company as of May 6, 2011. The Company also incurred $326,425 in late charges at a rate of 24% per annum
on the unpaid installments. At the time of the default the Company increased the balance owed to the note holders by 125% for default
penalties, bringing the balance of the notes including registration penalties, default penalties, and late fees to $9,053,213.
However, the note holders claimed that there had been a dilutive issuance of stock and the conversion rate in effect at the time
of default was $3.97 per share. Using this conversion rate to calculate the default penalty resulted in an additional penalty of
$13,248,548. The balance of the note, including late charges, interest, and penalties was $22,301,761 as of June 30, 2011.



Effective July 1, 2011, the Company entered
into an Exchange Agreement with each of the January 2011 note holders in order to settle our obligations for these notes. Pursuant
to the terms of the Exchange Agreement, each January 2011 Note holder agreed to exchange its claims against the Company, its subsidiaries
and certain of their respective current and former officers, directors and representatives for (i) the Company’s 4% convertible
notes ($4,950,000 original principal amount in the aggregate (the “July 2011 Notes”)), (ii) shares of 4% Series A Convertible
Preferred Stock of the Company (with an aggregate stated value of $6,701,000 (the “Preferred Stock”)) under a Certificate
of Designations of Series A Convertible Preferred Stock (the “Certificate of Designations”), and (iii) a warrant, expiring
5 years from the date of the receipt of Stockholder Approval (as defined in the Exchange Agreement), to purchase additional shares
of our common stock 3,778,725 shares of common stock in the aggregate under all the warrants (the “Warrants”)). Under
the Exchange Agreement, each of the January 2011 Note holders and their affiliated and related persons and entities also received
a mutual full release from the Company.



Each of the July 2011 Notes and shares
of Preferred Stock are initially convertible into shares of our common stock at a ceiling conversion price of $4.63 per share,
provided that if we make certain dilutive issuances (with limited exceptions), the conversion price of the July 2011 Notes and
the shares of Preferred Stock will be lowered to the per share price for the dilutive issuances. The Warrants are initially exercisable
for shares of our common stock at an exercise price of $4.63 per share, provided that if we make certain dilutive issuances (with
limited exceptions), the exercise price of the Warrants will be lowered to the per share price for the dilutive issuances. The
conversion prices of the July 2011 Notes and the shares of Preferred Stock and the exercise price of the Warrants are also subject
to adjustment in the case of stock splits, stock dividends, combinations of shares and similar recapitalization transactions. The
convertibility of a July 2011 Note and shares of Preferred Stock and the exercisability of the Warrant may be limited if, upon
conversion or exercise thereof, the holder thereof or any of its affiliates would beneficially own more than 9.9% (in the case
of a July 2011 Note and the shares of Preferred Stock held by such holder) or 4.9% (in the case of the Warrant held by such holder)
of our common stock.



Page 82 of 132







Each of the July 2011 Notes automatically
converts into shares of our common stock in four equal installments commencing August 1, 2011 ($1,237,500 in the aggregate under
all the Notes). The automatic conversion price under each of the Notes will be equal to the lower of (i) the conversion then in
effect or (ii) 70% of the arithmetic average of the three lowest closing bid prices of our common stock during the 20 trading day
period prior to the applicable automatic conversion date (the “July 2011 Note Automatic Conversion Price”). We must
make a pre-automatic conversion delivery of shares (the “July 2011 Note Pre-Automatic Conversion Shares”) to each holder
of a Note 20 trading days prior to the applicable automatic conversion date based the lower of (i) the conversion then in effect
or (ii) 70% of the arithmetic average of the three lowest closing bid prices of our common stock during the 20 trading day period
prior to the required delivery date of July 2011 Note Pre-Automatic Conversion Shares. On the automatic conversion date, to the
extent we owe a July 2011 Note holder additional shares in excess of the July 2011 Note Pre-Automatic Conversion Shares delivered
to such holder, we will issue such July 2011 Note holder additional shares of common stock, and to the extent we have issued excess
shares of common stock, such shares of common stock will be applied to future issuances of shares of common stock to such July
2011 Note holder.



The Preferred Stock and Exchange Notes
are different in form, but in substance, they are almost identical, except for minor differences having to do with interest rate
in case of default. Both instruments are mandatorily convertible in Companies shares of common stock based on the same formula
and on the same dates. Both the Preferred Stock and the Exchange Notes should be recorded at their face value of $6,701,000 and
$4,950,000, respectively. Both the Company and the five note holders agreed that the Company is indebted to them for a total sum
of $11,651,000. The preferred stock should only be considered “stock” in name but is in essence debt. The stated value
of $10/share is a mutually agreed upon value that represents the amount RPC owes to the preferred shareholders. The Preferred Stock
is due to be fully converted in four months and is, in essence, very similar to short term debt.



The Preferred Stock is convertible into
a variable number of shares of the Company's common stock. Therefore, in accordance with ASC 480-10-25-14, the Preferred Stock
is classified as a liability.



Commencing August 1, 2011, 167,525 shares
of Preferred Stock automatically convert into shares of our common stock in four equal installments. The automatic conversion price
with respect to each such share of Preferred Stock automatically converted will be equal to the lower of (i) the conversion then
in effect or (ii) 70% of the arithmetic average of the three lowest closing bid prices of our common stock during the 20 trading
day period prior to the applicable automatic conversion date (the “Preferred Automatic Conversion Price”). We must
make a pre-automatic conversion delivery of shares (the “Preferred Pre-Automatic Conversion Shares”) to each holder
of each such shares of Preferred Stock 20 trading days prior to the applicable automatic conversion date based the lower of (i)
the conversion then in effect or (ii) 70% of the arithmetic average of the three lowest closing bid prices of our common stock
during the 20 trading day period prior to the required delivery date of Preferred Pre-Automatic Conversion Shares. On the automatic
conversion date, to the extent we owe a holder of such shares of Preferred Stock additional shares in excess of the Preferred Pre-Automatic
Conversion Shares delivered to such holder, we will issue such holder additional shares of common stock, and to the extent we have
issued excess shares of common stock, such shares of common stock will be applied to future issuances of shares of common stock
to such holder.



Under the Exchange Agreement, we were also
obligated to (i) file an amended preliminary proxy statement with the SEC by July 5, 2011, to seek shareholder approval of an increased
amount of authorized shares to 30,000,000 shares of common stock, (ii) fix a date for the shareholders meeting no later than 20
days after receipt of final SEC comments relating to such proxy statement and (iii) obtain shareholder approval for the above proposal
by no later than August 31, 2011. If we failed to comply with any of the foregoing, it would have constituted an event of default
under the July 2011 Notes and a triggering event with respect to the Preferred Stock. The proxy was duly filed and the date of
the shareholders meeting was held on August 19, 2011.



If an event of default occurs under the
July 2011 Notes or the terms of the Certificate of Designation, we must redeem in cash any July 2011 Notes and shares of Preferred
Stock submitted to us for redemption at 125% of the greater of (i) the amount submitted for redemption unconverted principal amount
and (ii) the greatest equity value of the shares of common stock underlying the July 2011 Note or shares of Preferred Stock submitted
for redemption from the date immediately preceding the default until the date so submitted for redemption.



The July 2011 Notes contain embedded conversion
feature that was recorded as derivative liability in accordance with relevant accounting guidance due to the down-round protection
of the conversion price. The fair value on the grant date of the embedded conversion feature amounted to $3,430,693, as computed
using the Binomial Lattice option pricing model.



The Company determined that the Preferred
Stock should be recorded as a liability in the amount of the stated value of $6,701,000. The Preferred Stock also contains an embedded
conversion feature that was recorded as derivative liability. The fair value on the grant date of the embedded conversion feature
amounts was $4,644,257, as computed using the Binomial Lattice option pricing model.



Page 83 of 132







The Warrants was recorded as derivative
liability due to the down-round protection of the exercise price. The fair value of the Warrants on the grant date was $13,225,536,
computed using the Binomial Lattice option pricing model. The Company recorded a debt discount of $11,651,000, which represents
the fair value of the embedded conversion feature inherent in the July 2011 Notes, Preferred Stock and warrants, limited to the
face amount of the July 2011 Notes and Preferred Stock. During the year ended December 31, 2011, the Company recorded amortization
of debt discount of $3,448,988 and $4,669,023, which includes the accelerated debt discount of $973,988 and $1,318,523 for conversions
for the July 2011 Notes and Preferred Stock, respectively. The remaining unamortized debt discount was $1,501,012 and $2,031,977
for the July 2011 Notes and Preferred Stock, respectively. The debt discount remains to be amortized over the life of the debt
using the straight-line method over the terms of the debt, which approximates the effective-interest method.



The Exchange transaction was accounted
for as an extinguishment of debt and the Company recorded a gain on extinguishment of $1,001,275 in the accompanying consolidated
statement of operations for the year ended December 31, 2011.



On July 1, 2011, in accordance with the
terms of the July 2011 Notes and Preferred Stock, the Company issued in aggregate 1,153,184 shares of common stock constituting
the first July 2011 Notes pre-installment and pre-automatic conversion of Preferred Stock related to 2011 Exchange transaction.



On August 1, 2011, the first automatic
conversions required under the terms of the July 2011 Notes and Preferred Stock became due. To comply with the first automatic
conversions, the Company was required to issue approximately 2.2 million shares of its common stock. The Company did not have sufficient
authorized and unissued shares of common stock to complete the automatic conversions and the Company obtained an extension of the
first installment date from the July 2011 Note holders and Preferred Stock shareholders.



The amended terms of the July 2011 Notes and Preferred Stock
as follows:





| | · | Modified the automatic conversion price
(as defined in the July 2011 Notes and Preferred Stock) to be determined with respect to the First Installment Date by redefining
the Automatic Conversion Measuring Period to start on the issuance date of the July 2011 Notes and Preferred Stock and ending on
the trading day immediately preceding the First Installment Date.
| | - | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | Modified the installment dates for the
automatic conversions required under the terms of the July 2011 Notes and Preferred Stock as: August 22, 2011(First Installment),
October 4, 2011 (Second Installment), November 4, 2011(Third Installment), and December 8, 2011 (Maturity Date).
| | - | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | Modified the pre-installment dates related
to the automatic conversions required under the terms of the July 2011 Notes and Preferred Stock as: the Issuance Date, September
6, 2011, October 7, 2011, and November 9, 2011.
| | - | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | Waived any triggering events that would
occur on the original Automatic and Pre-Automatic Conversion Dates as defined in the Preferred Stock Certificate of Designation.
| | - | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------



On August 22, 2011, the Company calculated the true up shares
issuable for the 1st Installment and Automatic conversion resulting in the issuance in installments, a total of 3,322,379 shares
of common stock.



On September 6, 2011, the Company calculated
that 12,902,547 shares of common stockwhich were issued for the 2nd pre-installment and pre-automatic conversions. Due to the 9.9%
beneficial ownership cap limitation, the Company issued common shares at various dates during the period.



The true up shares issuable for the 2nd
installment and automatic conversion was 55,952,578 shares of common stock and was due on October 4, 2011. The shares issuable
exceeded the shares of available authorized common stock, as such, the Company was unable to satisfy its contractual obligation
and as a result, in accordance with the agreement, entered in default.



Page 84 of 132







As of each of the pre-installment and installment
dates, the Company calculates the amount of the partial prepayment using an allocation percentage based on the number of common
shares issued at the pre-installment versus the total number of common shares ultimately issued on the installment date.



Using same methodology, the Company determined
that for derivative liability valuation purpose, the dates of the pre-installments and installments, along with the end of reporting
period will constitute valuation events which is consistent with the contractual terms of the agreement.



Please see below the summary of share issuances and the related
amounts of liabilities extinguished during the year ended December 31, 2011.



|                              |  |                   |         |  | No of shares issuable for Conversion of |  |           | Liability amount extinguished | 
|----------------------------- |  | ----------------- | ------- |  | --------------------------------------- |  | --------- | ----------------------------- | 
|                              |  | Installm ent Date |         |  | Notes                                   |  |           | Preferred Stock               | 
|                              |  |                   |         |  |                                         |  |           |                               | 
|1st Pre-Installment           |  |                   | 7/1/11  |  |                                         |  | 489,937   |                               | 
|                              |  |                   |         |  |                                         |  |           |                               | 
|1st Installment               |  |                   | 8/22/11 |  |                                         |  | 1,411,533 |                               | 
|                              |  |                   |         |  |                                         |  |           |                               | 
|Subtotal                      |  |                   |         |  |                                         |  | 1,901,470 |                               | 
|                              |  |                   |         |  |                                         |  |           |                               | 
|2nd Pre-Installment           |  |                   | 9/6/11  |  |                                         |  | 5,481,728 |                               | 
|                              |  |                   |         |  |                                         |  |           |                               | 
|Total as of December 31, 2011 |  |                   |         |  |                                         |  | 7,383,198 |                               | 



Due to the occurrence of various events
of defaults under the 4% Notes and triggering events under the Series A Preferred Stock as well as significant decreases in the
market value of our common stock, we sought to restructure the terms of the securities issued to the 2011 Noteholders. Accordingly,
on November 28, 2011, we entered into separate exchange agreements with each of the 2011 Noteholders (the “November 2011
Exchange Agreements”), under which each 2011 Noteholders agreed to exchange all of their securities we issued to them under
the June 29, 2011, exchange agreements for the Radient securities described below.



The following Radient securities were issued
to the 2011 Noteholders in exchange for all of the securities we issued under the June 29, 2011 exchange agreements:



| | (a) | 402,441 shares of our Series B convertible preferred stock (the “Series B Preferred Stock”),
which Series B Preferred Stock, in accordance with its stated terms, (i) ranks senior to all of our other equity securities, (ii)
has a stated value of $10.00 per share, (iii) is initially convertible into approximately 72.1 million shares of our common stock
at an initial conversion price of $0.055825 per share (subject to adjustment as set forth below), (iv) accrues dividends at the
rate of 4% per annum which are payable in shares of common stock, in arrears upon each conversion of such stock and (v) contains
such other rights, preferences and limitations as are set forth in the certificate of designations of Series B Convertible Preferred
Stock;
| | --- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (b) | convertible notes, in the original principal amount of $4,950,000, which notes are initially convertible
into approximately 88.7 million shares of common stock at an initial conversion price of $0.055825 per share (subject to adjustment
as set forth below), and mature on November 28, 2012 (the “November Notes”);
| | --- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (c) | five year warrants to acquire up to approximately 313.5 million shares of common stock at an
                                                                 initial exercise price of approximately $0.055825 per share (subject to adjustment as set forth below) (the “Series A
                                                                 Warrants”), which are determined to have a fair value on November 28, 2011 of $32,131,867; and
| | --- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (d) | five year warrants, (the “Series B Warrants”) to acquire, for $500,000, an aggregate
of 50,000 shares of our preferred stock designated as Series C Convertible Preferred Stock (the “Series C Preferred Stock”),
which Series C Preferred Stock, in accordance with its stated terms, (i) ranks junior to the Series B Preferred Stock and senior
to all of the Company’s other equity securities, (ii) accrues dividends at the rate of 4% per annum, which are payable in
shares of common stock, in arrears upon each conversion of such stock, (iii) has a stated value of $10.00 per shares, (iv) is convertible
into shares of common stock, and (v) contains such other rights, preferences and limitations as are set forth in the certificate
of designations of Series C Preferred Stock.
| | --- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Page 85 of 132







By their terms, the Series B Warrants were
subject, at our election, to mandatory exercise under certain conditions. Having satisfied the conditions to elect a mandatory
exercise, we submitted a mandatory exercise notice to all of the Series B Warrant holders on November 29, 2011 requiring them to
exercise their Series B Warrants in full. The mandatory exercise date was November 30, 2011. All of the Series B Warrant holders
exercised such warrants for an aggregate exercise price of $500,000, which we received on November 30, 2011. The Series C Preferred
Stock is convertible into approximately 9.0 million shares of common stock at an initial conversion price of $0.056 per share.
After paying accrued legal fees of $66,220, we received net proceeds of $433,780 which we are obligated to use for ongoing working
capital for a period of not less than ninety (90) days from November 30, 2011.



At the same time we entered into the separate
November 2011 Exchange Agreements with each of the 2011 Noteholders, we entered into two separate agreements with the holders of
an aggregate of $8,056,258 of our convertible notes that we sold to two accredited investors (unrelated to the 2011 Noteholders)
in a registered direct offering in November 2009 (the “RDO Notes”). The RDO Noteholders waived the mandatory installment
payments, which were reset to the maturity date of April 15, 2013.



Each of the November Notes, the RDO Notes,
the shares of Series B Preferred Stock and shares of Series C Preferred Stock are initially convertible into shares of our common
stock at a conversion price equal to thelowest of:



| | (i) | $0.055825, (the “Fixed Conversion Price”),
| | --- | ------------------------------------------



| | (ii) | the price which is equal to the
product of (1) 80% multiplied by (2) the quotient of (A) the sum of each of the three lowest daily weighted average prices of
our common stock during the 20 consecutive trading day period immediately preceding the date of the conversion (as adjusted for
any stock split, stock dividend, stock combination or other similar transaction during any such 20 trading day period) or other
applicable date of determination, divided by (B) three, and
| | ---- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (iii) | the price which is equal to 80% of the closing bid price of our common stock on the trading day immediately preceding the date of conversion or other applicable date of determination (as adjusted for any stock split, stock dividend, stock combination or other similar transaction occurring on the applicable date of conversion or other applicable date of determination.
| | ----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



With limited exceptions, if we make certain
dilutive issuances, the conversion price of the November Notes and RDO Notes and the shares of November Preferred Stock are subject
to “full rachet” anti-dilution adjustments, and will be lowered to the per share price for the dilutive issuances.



The convertibility of the November Notes,
Series B Preferred Stock, the Series C Preferred Stock and the exercisability of the Series A Warrants may be limited if, upon
conversion or exercise thereof, the holder thereof or any of its affiliates would beneficially own more than 1% of our common stock.
Similarly, the convertibility of the RDO Notes may be limited if, upon conversion thereof, the holders thereof or any of its affiliates
would together beneficially own more than 4.9% of our common stock.



The Series A Warrants are initially exercisable
for shares of our common stock at an exercise price of $0.055825 per share; provided however, if we make certain dilutive issuances
(with limited exceptions), the exercise price of the Series A Warrants are subject to “full ratchet” anti-dilution
adjustments, and will be lowered to the per share price for the dilutive issuances. The Series A Warrants provide that if we fail
to file by December 31, 2011 a registration statement with the SEC covering the resale of any shares of common stock issuable upon
exercise of the Series A Warrants or fail to cause such registration statement to become effective by March 31, 2012, the holders
of the Series A Warrants may exercise such warrants on a “cashless basis.” In the event we comply with these conditions,
any shares of our common stock that are issuable upon exercise of the Series A Warrants (the “Series A Warrant Shares”)
at a time when an effective and current registration statement covering such Series A Warrant Shares is in effect may be exercised
only for cash.



Upon the occurrence of a Triggering Event
or Fundamental Transaction (as defined), each holder of our preferred stock has a right to force us to redeem any or all of their
shares of preferred stock. A Triggering Event is essentially the same as an event of default under the November Notes and a Fundamental
Transaction is essentially a sale of control of our company. See Note 16 below for additional information regarding the securities.



Page 86 of 132







The November 2011 Notes contain embedded
conversion feature that was recorded as derivative liability in accordance with relevant accounting guidance due to the down-round
protection of the conversion price. The fair value on the grant date of the embedded conversion feature amounted to $9,088,670,
as computed using the Binomial Lattice option pricing model.



The Company determined that the
Preferred Stock should be recorded as a liability in the amount of the stated value of $6,701,000 since it is not convertible
into a fixed number of shares. The Preferred Stock also contains an embedded conversion feature that was recorded as
derivative liability. The fair value on the grant date of the embedded conversion feature amounts was $7,389,199, as computed
using the Binomial Lattice option pricing model.



The Warrants was recorded as derivative
liability due to the down-round protection of the exercise price. The fair value of the Warrants on the grant date was $33,075,867,
computed using the Binomial Lattice option pricing model. The Company recorded debt discount in the aggregate of $9,474,410, which
represents the fair value of the embedded conversion feature inherent in the November 2011 Notes, Preferred Stock and warrants,
limited to the face amount of the November 2011 Notes and Preferred Stock. During the year ended December 31, 2011, the Company
recorded amortization of debt discount of an aggregate of $930,210 , which includes the accelerated debt discount of an aggregate
of $88,041 for conversions for the November 2011 Notes and Preferred Stock, respectively. The remaining unamortized debt discount
was $4,484,293 and $4,059,907 for the November 2011 Notes and Preferred Stock, respectively. The debt discount remains to be amortized
over the life of the debt using the straight-line method over the terms of the debt, which approximates the effective-interest
method.



The November 2011 Exchange Agreement transaction
was accounted for as an extinguishment of debt and as a result, the Company recorded a loss on extinguishment of approximately
$41.3 million in the accompanying consolidated statement of operations for the year ended December 31, 2011. The loss on extinguishment
amount represents the sum carrying value of the new convertible notes and preferred stock, net of the discounts, and the fair
value of the derivative liabilities related to the conversion features of the new debt and preferred stock and the down-round
provision of the exercise price of the warrants, which totaled approximately $49 million in excess of the remaining carrying value
of the previous convertible notes and preferred stock, net of the unamortized discounts, which totaled approximately $7.7 million.



We
registered (effective February 3, 2012) 16,000,000 of the Series A Warrant Shares under a registration statement. Such 16,000,000
Series A Warrant Shares represents approximately 5.1% of the approximately 313,500,000 Series A Warrant Shares (subject to adjustment)
that could be exercised under all of the Series A Warrants. We may also register for resale in future registration statements
additional Series A Warrant Shares.



During the year ended December 31, 2011,
Holders of the November Notes converted an aggregate of $41,390 principal and $71 corresponding interest into 742,705 shares of
Company common stock. As of December 31, 2011, the outstanding balance on these notes was of $4,908,610 and $17,998 accrued interest.



During the year ended December 31, 2011,
Holders of the November Notes converted an aggregate of 6,839 shares of Series B Preferred stock and $79 corresponding dividends
into 1,226,558 shares of Company common stock. As of December 31, 2011, the outstanding balance on the Series B Preferred stock
was of 395,602 shares Series B Preferred stock and $14,505 accrued dividends.



On November 30, 2011, the Series B warrants
were converted into 50,000 shares of Series C Preferred stock for $500,000. As of December 31, 2011, the outstanding balance on
the Series C Preferred stock was of 50,000 shares Series C Preferred stock and $1,833 accrued dividends.



On February 23, 2012, our common stock
was delisted from the OTCQX tier of the OTC Markets and moved to the OTCQB tier of the OTC Markets. We also disclosed our inability
to pay our accounts payable and other obligations in the ordinary course of business. As further disclosed, each such event constitutes
an event of default under certain of our outstanding notes, including the “2011 Noteholders” (as that term is defined
in our Form 8-K dated November 29, 2011); it also constitutes a triggering event under the terms of our Series B and Series C preferred
stock, which can result in redemption of such stock.



Between March 26, 2012 and April 3,
2012, we received an Event of Default Redemption Notice and a Notice of Redemption from four note holders. Pursuant to the
Event of Default Redemption Notice, each note holder elected to redeem their respective note in full, thereby requiring
immediate payment of the entire outstanding balance of their note. Failure to pay the balance by April 2, 2012, will activate
the late charges of 24% per annum until the redemption price is paid in full. Pursuant to the Notice of Redemption, each note
holder elected to redeem all of their respective shares of Series B Preferred Stock and Series C Preferred Stock at the
current redemption price, which was required to be paid by April 2, 2012. Our failure to pay by April 2, 2012 has triggered
interest payments at the rate of 2% per month for each unredeemed share until the redemption price is paid in full.



Page 87 of 132







On May 15, 2012, we completed an Agreement
with the 2011 Noteholders, severally and not jointly, for the exercise of an aggregate of $150,000 worth of our Series A Common
Stock Purchase Warrants at an exercise price of $0.02619 per share. The proceeds received from such Warrant exercise, shall be
used solely and exclusively to enable us to keep our Registration Statement on Form S-1 filed under the Securities Act of 1933,
as amended, which the Securities and Exchange Commission declared effective on February 14, 2012, current and maintain compliance
with our reporting requirements under the Securities Exchange Act of 1934, as amended.



As a condition to the exercise of the Warrants,
we agreed that following the date of the Agreement and through and including 5:00 p.m. (EDT) on August 31, 2012, we will not file
in any U.S. Bankruptcy Court a voluntary petition for reorganization under Chapter 11 of Title 11 of the United States Code or
seek to liquidate under Chapter 7 of such Code. Additionally, each of the 2011 Noteholders, severally and not jointly, agreed to
forebear from exercising any of their rights and remedies, whether at law or in equity, against us and our current and former directors
and officers for a period that shall not exceed the earlier to occur of (i) August 31, 2012, or (ii) a breach by us of any of our
other covenants and agreements contained in the prior agreements with the 2011 Noteholders or in the current Agreement, including,
without limitation, our commitment to file with the SEC our 2011 Form 10-K by June 30, 2012 and our March 31, 2012 Form 10-Q by
July 15, 2012. The 2011 Noteholders further agreed that in the absence of a further breach of the terms of the Agreement or any
of the other agreements between us and the 2011 Noteholders, that each of the previously issued default notices shall be deemed
to be withdrawn ab initio upon execution of the Agreement.



Additionally, as part of the Agreement
and in order to provide for payment of past due legal fees, we agreed to issue to our legal counsel, Hunter Taubman Weiss LLP,
a $300,000 unsecured convertible 4% Company note payable on April 30, 2015, which shall (i) accrue interest at the annual rate
of 4% per annum, (ii) be convertible into our Common Stock at a fixed conversion price of $0.01 per share, (iii) be subject to
prepayment at the option of the Company, (iv) contain full ratchet and other customary anti-dilution protection, and (v) not be
subject to any mandatory installment or other mandatory prepayment provisions prior to the April 30, 2015 maturity date.



Settlement Agreement Promissory Notes



On May 10, 2011, we entered into a
Settlement Agreement with Alpha Capital Anstalt and Whalehaven Capital Fund Ltd. (the “Plaintiffs”) (see Note
10), which was amended on May 23, 2011 (See Note 10). Pursuant to the Settlement Agreement we agreed to issue that number
of shares of our common stock equal in value to $10,912,055 at the time of issuance (the “Settlement
Amount”); however, we were not obligated to issue the shares until we received court approval to issue such shares
pursuant to the provisions of Section 3(a)(10) of the Securities Act of 1933(“Court Approval”), pursuant to which
the shares will be free trading, and NYSE Amex or shareholder approval, if required. Under the terms of the Settlement
Agreement, upon Court Approval, we were required to issue Plaintiffs as many shares of our common stock as possible to reach
the Settlement Amount that the NYSE Amex has previously approved for issuance to the Plaintiffs. In addition, to account for
the time it would take to receive Court Approval, as well as NYSE Amex or shareholder approval of the ultimate number of
shares issuable to obtain the Settlement Amount, and therefore their shares, the Plaintiffs agreed to accept a promissory
note (the “Promissory Notes”) for the monetary value of that number of additional shares that would be required
to be issued to achieve the Settlement Amount upon Court Approval based on a pre-determined formula set forth in the notes.
We received Court Approval on May 24, 2011. The notes were delivered upon Court Approval; they bear 8% interest and mature
four months after issuance. The note were required to be paid on or before September 24, 2011 to avoid a judgment for the
remaining principal, if any, at such time.



As amended, Plaintiffs maintain the right
to convert the note into shares of our common stock at a pre-determined formula as set forth in the notes, which is subject to
adjustment although no shares shall be issued until we have NYSE Amex or shareholder approval of same, if required. Throughout
the term of the note, if we no longer need NYSE Amex or shareholder approval, all shares issuable pursuant to the settlement agreement
shall be issued. Upon the occurrence of an Event of Default, the note will become immediately due and payable. Under the Settlement
Agreement, Plaintiffs are entitled to entry of judgment in the amount of principal outstanding, if any, on the maturity date. The
Settlement Agreement also contemplates the issuance of additional shares to Plaintiffs or the return of shares to us based upon
variances in the market price of our common stock between the date we receive Court Approval and sixty days following the maturity
date of the notes. Pursuant to the Settlement Agreement, we agreed to pay Plaintiffs’ attorney fees of $75,000. Once the
initial shares and promissory note are issued, the parties shall file a Stipulation of Discontinuance of the lawsuit with the relevant
court.



Page 88 of 132







On or about June 23, 2011, we advised Plaintiffs
that due to the fact that each of the convertible notes held by Whalehaven and Alpha Capital are, by their stated terms, immediately
convertible at the option of the holders into more than ten percent (10%) of the issued and outstanding shares of common stock
of the Company, each of the Plaintiffs is an affiliate of the Company as defined in Rule 144(a) promulgated under the Securities
Act. As such, any additional Settlement Shares issued to the Plaintiffs under the Settlement Agreement would have to comply with
the applicable provisions of the Securities Act and specifically Rule 144 promulgated thereunder with regard to resales. Accordingly
we advised plaintiffs that the additional 820,000 shares issued to Plaintiffs pursuant to Section 3(a)(10) may only be resold in
compliance with Rule 144. These shares are not “restricted securities” within the meaning of Rule 144(a); they are
not subject to the holding period limitations of Rule 144(d). However, they are subject to the other relevant provisions of Rule
144, including (i) the limitation of the amount of securities that may be sold by an affiliate pursuant to Rule 144(e)(1) and the
manner of sale pursuant to Rule 144(f).



Based on the available amount of shares
the NYSE Amex previously approved for the Plaintiffs, upon Court Approval on May 24, 2011, we issued the Plaintiffs an aggregate
of 20,000 shares of our common stock valued at $140,400 and issued promissory notes for an aggregate amount of $10,771,655. As
a result of this agreement, we recorded legal settlement expense of $10,987,055.



In addition, the promissory note contains
an embedded conversion feature. As such, the conversion feature was valued on the grant date using the Binominal lattice option
pricing model and $2,684,286 was recorded as an addition to the derivative liability.



On June 23, 2011, we were delisted from
the NYSE Amex and no longer required NYSE Amex approval to issue the shares due to the promissory note holders. On June 29, 2011,
we issued to the promissory note holders an aggregate of 820,000 shares of our common stock valued at $2,949,950. The balance of
the promissory note and accrued interest was $7,821,705 and $86,707 as of June 30, 2011, respectively.



As reported in our Current Report Form
8-K filed on July 25, 2011, on July 19, 2011 the Plaintiffs wrote a letter to the U.S. District Court - Southern District of New
York alleging we failed to perform our obligations under the Original Settlement Agreement. The Company disputed this allegation.



On August 25, 2011, we entered into new
settlement agreement with Plaintiffs which amended and restated the Original Settlement Agreement (the “Final Settlement
Agreement”), which was approved by the Court on August 26, 2011. A complete copy of the Final Settlement Agreement and related
documents are included in our 8-K filed on August 29, 2011. The Final Settlement Agreement was separately consented to by Iroquois
Master Fund Ltd., Cranshire Capital, LP, Bristol Investment Fund Ltd., Kingsbrook Opportunities Master Fund LP and Freestone Advantage
Partners LP (collectively, the “2011 Note holders”).



Under the terms of the Final Settlement
Agreement, we issued 8% convertible promissory notes (“Notes”) in the principal amount of $4,559,842.41 to the Plaintiffs.
The balance of the promissory notes after all the stock issuances was in the amount of $7,821,705 in aggregate for Alpha and Whalehaven.
The Final Settlement Agreement required issuance of new notes in the aggregate of $8,056,258. The difference of $234,554 was treated
as a penalty and recorded to the interest expense for year ended December 31, 2011.



We are obligated to retire the Notes in
monthly installments, commencing January 31, 2012, by payment in cash or (at our sole option) by delivery shares of our common
stock in an amount equal to 6.25% of the initial principal amount of each Note, plus accrued interest. In the event we elect to
make installment payments in common stock, we will be obligated to make monthly delivery of shares of common stock that are not
subject to any restrictions on resale under Rule 144 under the Securities Act (“Non-Restricted Shares”) valued at 80%
of the three lowest volume weighted average closing prices of our common stock over the 20 trading days immediately prior to each
installment payment date. It is our present intention to amortize the Notes with our common stock, although we may elect to pay
one or more such installments in cash.



The Notes permit the Plaintiffs to convert
the Notes into our common stock, although the Final Settlement Agreement and the Notes contain “blocker” provisions
designed to prevent the Plaintiffs from becoming “beneficial owners” (as defined in Section 13(d) of the Securities
Exchange Act of 1934, as amended (the “Exchange Act “) of more than 9.99% of our common stock.



In addition, we agreed to issue Plaintiffs
additional Non-Restricted Shares (the “True Up Shares”) to adjust, based on recent reductions in the closing prices
of our publicly trades shares, the number of shares we previously issued to the Plaintiffs in connection with prior conversions
of the notes we issued under the Original Settlement Agreement. The True Up Shares are issuable on one occasion only for each individual
Plaintiff, at the Plaintiff request, any time between November 2, 2011 and January 3, 2012.



Page 89 of 132







We agreed to reserve an aggregate of 7
million shares of authorized and previously unissued common stock for potential issuance to the Plaintiffs for issuance upon their
conversion of the Notes. We further agreed to keep a sufficient number of shares of Common Stock for purposes of enabling issuing
all of the Settlement Shares pursuant to the Final Settlement Agreement and the Notes.



On October 11, 2011, the Company’s
Board of Directors consented to reserve all Common Stock shares available for issuance as of that date of approximately 4.12 million
shares.



Pursuant to the Final Settlement Agreement
we were released from all liability and claims from Plaintiffs arising under the Original Settlement Agreement.



During the year ended December 31, 2011,
note holders converted $2,949,950 of principal and $0 of interest, representing 27% of the outstanding balance of the promissory
notes. The Company issued 820,000 shares of its common stock upon conversion of the notes. The balance as of December 31, 2011
was $8,056,258 in principal and $224,251 of accrued interest.



At the same time we entered into the separate
November 2011 Exchange Agreements with each of the 2011 Noteholders, we entered into two separate agreements with the holders of
an aggregate of $8,056,258 of our convertible notes that we sold to two accredited investors (unrelated to the 2011 Noteholders)
in a registered direct offering in November 2009 (the “RDO Notes”). The RDO Noteholders waived the mandatory installment
payments, which were reset to the maturity date of April 15, 2013.



Each of the November Notes, the RDO Notes,
the shares of Series B Preferred Stock and shares of Series C Preferred Stock are initially convertible into shares of our common
stock at a conversion price equal to thelowest of:



| | (i) | $0.055825, (the “Fixed Conversion Price”),
| | --- | ------------------------------------------



| | (ii) | the price which is equal to the product of (1) 80% multiplied by (2) the quotient of (A) the sum of each of the three lowest daily weighted average prices of our common stock during the 20 consecutive trading day period immediately preceding the date of the conversion (as adjusted for any stock split, stock dividend, stock combination or other similar transaction during any such 20 trading day period) or other applicable date of determination, divided by (B) three, and
| | ---- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (iii) | the price which is equal to 80%
of the closing bid price of our common stock on the trading day immediately preceding the date of conversion or other applicable
date of determination (as adjusted for any stock split, stock dividend, stock combination or other similar transaction occurring
on the applicable date of conversion or other applicable date of determination.
| | ----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



With limited exceptions, if we make certain
dilutive issuances, the conversion price of the November Notes and RDO Notes and the shares of November Preferred Stock are subject
to “full rachet” anti-dilution adjustments, and will be lowered to the per share price for the dilutive issuances.



The convertibility of the November Notes,
Series B Preferred Stock, the Series C Preferred Stock and the exercisability of the Series A Warrants may be limited if, upon
conversion or exercise thereof, the holder thereof or any of its affiliates would beneficially own more than 1% of our common stock.
Similarly, the convertibility of the RDO Notes may be limited if, upon conversion thereof, the holders thereof or any of its affiliates
would together beneficially own more than 4.9% of our common stock. See Note 16 below for additional information regarding the
securities.



On October 27, 2011 Alpha exercised its
right for True Up Shares, 28,478,988 True Up Shares as determined to be issuable. Due to restrictions for Maximum percentage of
9.99% Beneficial Ownership, Alpha requested issuance in installments at their preference, as such, during the year ended December
31, 2011, 3,720,000 shares were issued.



Page 90 of 132







On October 31, 2011 Whalehaven exercised
its right for True Up Shares, 21,837,245 True Up Shares as determined to be issuable. Due to restrictions for Maximum percentage
of 9.99% Beneficial Ownership, Whalehaven requested issuance in installments at their preference, as such, during the year ended
December 31, 2011, 2,196,000 shares were issued.



During the year ended December
31, 2011, the Company recognized $718,320 of interest expense related to the True Up Shares issued to Alpha and Whalehaven pursuant
to the terms noted above. Such shares were valued based on the market price of the Company’s common stock on the date the
shares are issuable.



In addition, during the
year ended December 31, 2011, Alpha and Whalehaven converted an aggregate of $2,949,950 of principal into 820,000 shares of the
Company’s common stock.



Embedded Conversion Features and Warrants



The 2010 Notes, the January 2011 Notes,
the July 2011 Exchanged Notes, the November 2011 Exchanged Notes and the Promissory Notes carry embedded conversion features and
warrants which are accounted for as derivative instruments under the relevant accounting guidance. The Company uses the Binomial
Lattice model to estimate the fair value of the derivative instruments at their grant dates, conversion or exercise dates, principal
payment dates, penalty and triggering dates, and quarter ends.



The warrants related to the 2010 Notes,
the January 2011 Notes, July 2011 Exchanged Notes, and the the November 2011 Exchanged Notes carry a “cashless exercise”
feature. This cashless exercise feature has value to the holder. To evaluate the value of the “cashless exercise” feature,
the Company used the following assumptions. As stated in the warrant agreement, upon an effective registration statement the cashless
exercise feature will no longer be available to the holder. As of December 31, 2011, the Company has not filed a registration statement
which has resulted in the continuance of the cashless exercise feature. The Company also evaluated the likelihood of the warrant
holders exercising their warrants under the cashless exercise feature versus a cash exercise from the original grant date of each
warrant until the estimated date the registration statement is declared effective. For the 2010 Notes, based on the cashless exercise
notices received by the Company through the date of this filing and based on our best estimate of the warrant holders’ intent
going forward, the Company believes a conservative estimate is that there is a 90% likelihood that the investors would exercise
under the cashless exercise provision and 10% likelihood that they would effect a standard exercise via cash. For January 2011
Notes, July 2011 Exchanged Notes and the November 2011 Exchanged Notes, considering $0 intrinsic value of the warrants as of December
31, 2011, and the fact that there was no exercise notices received, the Company considered a 0% likelihood that the investors would
exercise under the cashless exercise provision.



The Company values the warrants (assuming
standard cash exercises,) under the Binomial Lattice option pricing model (“Binomial Model — Normal”). In addition,
the Company values the same warrants under a separate Binomial Lattice option pricing model (“Binomial Model — Cashless”),
assuming that the holder would exercise under the cashless exercise feature prior to the date of the registration statement being
declared effective. Under the Binomial Model — Cashless, the Company uses a much shorter expected term (commensurate with
the assumed date that the Company expect the registration statement to be declared effective), resulting in different volatility
amounts and discount rates. One other factor that is considered for the value estimated under the Binomial Model — Cashless
is that if the holder of the warrant decided to exercise under the cashless exercise feature, the number of warrant shares available
to the holder is then computed under the formula prescribed by the warrant agreement. On some dates, it results in potentially
more shares being issued to the holder than what are stated on the holder’s warrant agreement and on some dates it results
in potentially less shares being issued to the holder than what are stated on the warrant agreement.



The total values computed under each Binomial
Model are then assigned a likelihood or probability that the investor may exercise under either scenario. The Company used 90%/10%
for 2010 Notes and 0%/10% for January 2011 Notes, July 2011 Exchanged Notes and the November 2011 Exchanged Notes for the cashless
exercise /cash exercise proportion, respectively, to arrive at the estimated fair value assigned to warrant as of their grant date
valuation events, and as of December 31, 2011.



See Note 1 for more information on accounting
for derivative liabilities related to embedded conversion features and warrants with down round protection and assumptions used
for valuation of these derivative liabilities.



Page 91 of 132







Other Debt



Consulting Agreement



On September 10, 2009, the Company entered
into a Consulting Agreement (the “Consulting Agreement”) with Cantone Asset Management, LLC (“Cantone Asset”)
whereby Cantone Asset provided guidance and advice related to negotiating the terms of the Company’s outstanding Series 1
and Series 2 Senior Notes and continued services to assist the Company to coordinate with the holders of the Series 1 and Series
2 Senior Notes. In consideration of Cantone Asset’s service, the Company agreed to pay monthly consulting fees of $12,000
per month for a period of twelve (12) months and issue to the Consultant a five-year warrant to purchase 8,000 shares of the Company’s
common stock at an exercise price of $15.00 per share (the “Cantone Warrant”). This warrant was valued at $88,000 using
the Black-Scholes model with a discount rate of 2.38% and a volatility of 97.27%.



In March 2010, in an effort to further
reduce its cash expenditures, the Company also amended the consulting agreement with Cantone Asset. Under the amended consulting
agreement, Cantone Asset agreed to accept shares of the Company’s common stock in lieu of the Cash Consulting Fee and as
consideration therefore, the Company agreed to reduce the warrant exercise price of the Cantone Warrants to $7.00 per share (the
“Amendment”). Pursuant to the Amendment, and subject to stockholder approval, the Company would issue Cantone Asset
an aggregate of 20,571 shares of the Company’s common stock (the “Amendment Shares”), which did not include the
shares of common stock underlying the Cantone Warrants. Pursuant to the Amendment, the Company was required to obtain shareholder
approval by September 15, 2010. As previously stated the Company was unable to hold a meeting by such date due to the SEC’s
review of the periodic reports that were required to be mailed with the corresponding proxy statement. Accordingly, the Company
sought and obtained Cantone Asset’s agreement to instead hold the shareholder meeting by November 15, 2010; in exchange for
which, we agreed to increase the cash fee owed to Cantone Asset by 25% and instead of paying the amount owed in cash we agreed
to issue them 25,714 Amendment Shares (the “Extension”), which would be full and complete payment of all fees owed
to Cantone Asset under the Agreement and the Amendment. Pursuant to the Extension, Cantone Asset also agreed to waive any defaults
related to the Company’s failure to hold the shareholder meeting by September 15, 2010. The shareholders approved all of
the shares underlying the Debt Exchange Agreement at the December 3, 2010 meeting and the NYSE Amex approved the shares on January
3, 2011. The 25,714 amendment shares were issued on January 12, 2011, which represents full and complete payment of all fees owed
to Cantone Asset under the Agreement and the Amendment.



NOTE 9 — EMPLOYMENT CONTRACT TERMINATION LIABILITY



In October 2008, the Company’s former
chief executive officer agreed to retire from his employment with the Company. The Company negotiated a settlement of its employment
contract with the former chief executive officer under which he received $150,000 upon the effective date of the agreement, including
$25,000 for reimbursement of his legal expenses. In addition the Company agreed to pay $540,000 in monthly installments of $18,000,
commencing January 31, 2009, to continue certain insurance coverage, and to extend the term of options previously granted which
would have expired shortly after termination of employment. Pursuant to FASB ASC 420-10, the Company recorded a liability of approximately
$517,000 for the present value of the monthly installments and insurance coverage’s due under the settlement agreement. Approximately
$0 and $85,000 are included in accrued salaries and wages in the accompanying consolidated balance sheets at December 31, 2011
and 2010, respectively.



During the year ended December 31, 2011
and 2010, the Company paid approximately $150,831 and $282,700, respectively, under this arrangement to the Company’s former
CEO.



NOTE 10 — COMMITMENTS AND CONTINGENCIES



Operating Leases



The Company leases its laboratory and manufacturing
space under an operating lease agreement that expired on September 1, 2011. The lease required monthly lease payments of $6,944.
Since September 2011, we are on a month-to-month lease basis.



Rent expense under non-cancelable leases
was approximately $55,000 and $90,000, and $28,000 and $0 under cancelable leases, for the year ended December 31, 2011and 2010,
respectively.



Page 92 of 132







Litigation



AcuVector Group



On February 22, 2002, AcuVector Group,
Inc. (“AcuVector”) filed a statement of claim in the Court of Queen’s Bench of Alberta, Judicial District of
Edmonton relating to the Company’s CIT technology acquired from Dr. Chang in August 2001. The claim alleged damages of $CDN
20 million and sought injunctive relief against Dr. Chang for, among other things, breach of contract and breach of fiduciary duty,
and against the Company for interference with the alleged relationship between Dr. Chang and AcuVector. The Company filed a motion
to dismiss all claims and the motion was granted in favor of the Company dismissing the action on September 30, 2011. The Company
also defended a companion case filed in the same court the Governors of the University of Alberta filed against the Company and
Dr. Chang in August 2003. The Court approved an order to dismiss the cases. However, opposing counsel, who approved the form of
order, filed an appeal on December 23, 2011. Although we intend to defend the dismissal vigorously as we believe both actions are
without merit, it is possible the order will be overturned and then if either AcuVector or the University is successful in their
claims, we may be liable for substantial damages, our rights to the technology will be adversely affected and our future prospects
for exploiting or licensing the CIT technology will be significantly impaired.



Hudson Bay Fund



On June 11, 2010, Hudson Bay Fund, LP.
(“Hudson Bay”) filed a statement of claim in the Court of Cook County, County Department, Law Division, State of Illinois
relating to their participation in the Second Closing of the Note Financings. The claim alleges that a Trigger Event occurred,
because the respective registration statement was not declared effective on or before June 1, 2010. As a result of the Trigger
Event, the balance was immediately increased to 125% of the outstanding balance; we noted this Trigger Event and recorded same
in our accompanied financial statements. Moreover, the claim alleged that an additional Trigger Event occurred because we did not
cure the first Trigger Event within five trading days. As a result of this alleged Second Trigger Event, Hudson Bay alleges that
the outstanding balance of the Note should be immediately increased by an additional 125%. On January 21, 2011 Hudson agreed to
exchange the notes for an aggregate of 1,140,357 shares of the Company's common stock pursuant to Section 3(a)(9) of the Securities
Act of 1933, as amended. As a result of the exchange, such notes are no longer outstanding and the Company and Hudson accordingly
agreed to execute and file an order dismissing the June 11, 2010 compliant, with prejudice. The dismissal order was filed on January
21, 2011.



Class Action



On March 11, 2011, a putative shareholder
class action was filed against the Company and two of its officers alleging that they violated federal securities laws by misrepresenting
the relationship between the Company and third parties involved in the Company’s clinical studies of the Onko-Sure® test
kit. The trial court granted in part, and denied in part, the defendants’ motions to dismiss the complaint, and the case
is now proceeding to discovery. The Company and defendant officers vehemently deny the allegations in the complaint and are vigorously
defending the action. Due to the uncertain nature of litigation and the early stage of the lawsuit, we cannot calculate the potential
damages – nor does the complaint seek any specific monetary amount of damages.



Alpha Capital and Whalehaven



On December 10, 2010, Alpha Capital Anstalt
(“Alpha Capital”) and Whalehaven Capital Fund Ltd. (“Whalehaven Capital and with Alpha Capital, the “Plaintiffs”)
filed a complaint against us regarding the number of warrants they received in the Registered Direct Offering (“RDO”)
that we completed in November 2009 and the shareholder vote obtained at our December 3, 2010 annual shareholder meeting. The Plaintiffs
alleged that the effective price of the notes we issued pursuant to the private financing we completed in March and April 2010,
and of the shares we later issued to two such note holders in settlement of a lawsuit with same, is lower than what we claim it
to be and that such alleged effective price requires a greater reset to the exercise price of the warrants they received in the
RDO. Additionally, they allege that we solicited votes against one of the proposals related to the RDO that was proposed at the
December 3, 2010 annual shareholder meeting. The Plaintiffs sought relief from the court involving additional shares issuable pursuant
to the exercise of the warrants they received in the RDO and cash damages.



Page 93 of 132







As reported in the Company’s Form
8-K dated May 17, 2011, on May 10, 2011, we entered into a Settlement Agreement with the Plaintiffs pursuant to which we agreed
to issue that number of shares of our common stock equal in value to $10,912,055 at the time of issuance (the “Settlement
Amount”). On May 24, 2011 we received court approval to issue such shares pursuant to the provisions of Section 3(a)(10)
of the Securities Act of 1933, as amended. Under the terms of the court approved settlement, the parties filed a Stipulation of
Discontinuance of the lawsuit with the relevant court. As part of the Settlement Agreement, Alpha Capital and Whalehaven Capital
retained all of the warrants the Plaintiffs received in the RDO and in the private financing we closed in March and April 2010.
We are obligated to issue to Alpha Capital and Whalehaven Capital as many shares of our common stock as possible to reach the Settlement
Amount that the NYSE Amex had previously approved for issuance to the Plaintiffs. On May 25, 2011, we issued an aggregate of 20,000
shares of our common stock in accordance with the Settlement Agreement; 11,320 shares to Alpha Capital and 8,680 shares to Whalehaven.
Throughout the term of the note, if we no longer need NYSE Amex or shareholder approval, all shares issuable pursuant to the Settlement
Agreement shall be issued. On June 23, 2011, the Company was no longer listed on NYSE Amex; and therefore, on June 29, 2011, we
issued an aggregate of 820,000 of our common shares; 464,120 shares to Alpha Capital and 355,880 shares to Whalehaven Capital.
In addition, and in order to account for the time it may take to receive shareholder approval to authorize sufficient additional
shares that are issuable to them, the Plaintiffs agreed to accept a promissory note for the monetary value of that number of additional
shares that would be required to be issued to achieve the Settlement Amount upon Court Approval based on a pre-determined formula
set forth in the Notes. The notes bear 8% interest and mature four months after issuance. We maintain the right to pay the note
back in cash or shares of common stock based upon a pre-determined formula set forth in the notes. Upon the occurrence of an event
of default, the note will become immediately due and payable. Under the Settlement Agreement, Plaintiffs are entitled to entry
of judgment in the amount of principal outstanding, if any, on the maturity date. The Settlement Agreement also contemplates the
issuance of additional shares to Plaintiffs or the return of shares to us based upon variances in the market price of our common
stock between the date we receive Court Approval and sixty days following the maturity date of the notes.



On June 23, 2011, we advised Plaintiffs
that due to the fact that each of the convertible notes held by Whalehaven and Alpha Capital are, by their stated terms, immediately
convertible at the option of the holders into more than ten percent (10%) of the issued and outstanding shares of common stock
of the Company, each of the Plaintiffs is an affiliate of the Company as defined in Rule 144(a) of the Securities Act. As such,
any additional Settlement Shares issued to the Plaintiffs under the Settlement Agreement would have to comply with the applicable
provisions of the Securities Act and specifically Rule 144 promulgated thereunder with regard to any resale. Accordingly we advised
plaintiff’s that the additional 20.5 million shares issued to them pursuant to Section 3(a)(10) may only be resold by Plaintiffs
in compliance with Rule 144. These shares are not “restricted securities” within the meaning of Rule 144(a), they are
not subject to the holding period limitations of Rule 144(d). However, they are subject to the other relevant provisions of Rule
144, including (i) the limitation of the amount of securities that may be sold by an affiliate pursuant to Rule 144(e)(1) and the
manner of sale pursuant to Rule 144(f).



On July 19, 2011 Plaintiffs wrote a letter
to the Court disputing our position that they are affiliates and seeking judgment in default of the Settlement Agreement. We strongly
believe that a default has not occurred; we maintain that we are in compliance with the terms of the Settlement Agreement and we
are vigorously defending our position.



On August 19,
2011, the Company entered into a Memorandum of Understanding with Alpha Capital and Whalehaven. On August 25, 2011, a Final Settlement
Agreement was reached to settle the July 19, 2011 Letter. On August 26, 2011, the Final Settlement Agreement was recorded and approved
in the Court. We have since modified certain terms of the Final Settlement to impose a trading limitation on the Plaintiffs sale
of our common stock and a lower ownership cap.The Plaintiffs also waived the installment payments owed to them under their
notes, although we remain liable for any principal and interest outstanding on the maturity date.



January 2011 Noteholders



As reported in the Company’s Form
8-K dated May 11, 2011, we were in default to each of Iroquois Master Fund Ltd., Cranshire Capital, L.P., Freestone Advantage Partners,
L.P., Bristol Investment Fund, Ltd. and Kingsbrook Opportunities Master Fund LP, (collectively, the “2011 Note holders”),
the holders of our convertible notes due December 1, 2011 (the “2011 Notes”) in the original principal amount of $8,437,500.
As a result of such defaults, our total liabilities (including accrued interest, penalties and default redemption payments) to
the 2011 Note holders aggregated $22,301,761. We entered into an exchange agreement on June 29, 2011, with each of the 2011 Note
holders (the “Exchange Agreement”) in order to settle our obligations to each of the 2011 Note holders. This transaction
was legally consummated and recorded for financial reporting purposes on July 1, 2011.



Following a fairness hearing held on September
30, 2011, in the Supreme Court of the State of New York (the “Court”), the Court entered an order approving (i) the
fairness of the terms and conditions of the proposed exchange and the transactions contemplated by the Exchange Agreement, (ii)
the terms and conditions of the proposed exchange and the transactions contemplated by the Exchange Agreement and (iii) the issuance
of the Notes, the shares of Preferred Stock and the Warrants pursuant to the exemption from registration under Section 3(a)(10)
of the Securities Act of 1933, as amended (the “3(a)(10) Order”).



Page 94 of 132







As reported in the Company’s Form
8-K dated November 28, 2011, on November 28, 2011, we entered into separate exchange agreements with each of the 2011 Noteholders
(the “November Exchange Agreements”), pursuant to which each 2011 Noteholder agreed to exchange all of its respective
Initial Settlement Securities for the securities described below. Due to the occurrence of various events of defaults under the
4% Notes and triggering events under the Preferred Stock, the Company determined it was in its best interest to enter into the
November Exchange Agreement (See Note 8).



Each of the 2011 Noteholders agreed separately
with the Company in its respective November Note that from and after the issuance of its respective November Note until the occurrence
of a Termination Event (as defined in its November Note) such 2011 Noteholder will not sell an aggregate number of Covered Shares
(as defined in its November Note) (i.e. shares of Common Stock issued upon exercise of such 2011 Noteholder’s Series A Warrants
and upon conversion of such Noteholder’s November Note, shares of Series B Preferred Stock and Series C Preferred Stock (if
any shares of Series C Preferred Stock are issued to such Noteholder) on any trading day that exceed an agreed upon percentage
of the aggregate daily trading volume of the Common Stock on such trading day (which initially range from 0.24% to 4.39% for each
of the 2011 Noteholders). The initial percentage of the daily trading volume in such Noteholder’s November Note increases
by 100% once the Common Stock trades for greater than or equal to $1.25 per share (adjusted for stock splits, combinations and
other similar transaction), by an additional 50% once the Common Stock trades for greater than or equal to $2.50 per share (adjusted
for stock splits, combinations and other similar transaction) and then no longer applies once the Common Stock trades for greater
than or equal to $3.75 per share (adjusted for stock splits, combinations and other similar transaction) or another Termination
Event occurs.



Although the November Notes rank senior
to all of the Company’s outstanding and future debt, with a few exceptions, they rank pari passu with the notes held by the
Plaintiffs. However, neither of the notes issued to the Plaintiffs may be amended, waived, extended or otherwise modified in any
manner or respect without the prior written consent of the holders of the November Notes.



Upon the occurrence of a Triggering Event
or Fundamental Transaction, as such terms are defined in the Series B Certificate of Designations and the Series C Certificate
of Designations, each holder of shares of the November Preferred Stock has a right to force us to redeem any or all of their shares
of the November Preferred Stock then held by such holder. The transactions contemplated by the November Exchange Agreements were
consummated on November 28, 2011.



Ironridge



On December 8, 2011, Ironridge Global IV,
Ltd. (“Ironridge”) filed a complaint against us in the Superior Court of California, Los Angeles County. Ironridge
claims that we breached a contract with them by allegedly discussing and then entering into transactions to settle certain of our
outstanding liabilities with holders of our convertible securities during a 30-day exclusivity period, during which Ironridge claims
it had the exclusive right to do so. Ironridge is seeking damages in excess of $30.0 million. We believe that the Ironridge claims
are totally without merit, that Ironridge met with substantially all of the holders of such convertible notes and related securities
and, in fact, did business with certain of such creditors who elected to deal with Ironridge. As such, we believe that we performed
all of our obligations under such contract and intend to defend our position vigorously.



Employees



On May 16 and May 21, 2012, two former
employees filed a Notice of Claim and Conference with the Labor Commissioner; State of California against us for unpaid wages accrued
from February 2012 to March 2012 and accrued vacation pay. The special committee of the Board of Directors is reviewing a plan
out forth by management to resolve outstanding salaries and accrued vacation. Due to the
shortage of working capital, we were unable to pay premiums associated with our Directors and Officers insurance. As
a consequence, on June 25, 2012, we were informed by two members of our Board of Directors of their resignation. As a result,
we have only one independent Director serving on our Board at this time.



Other



Other than the above mentioned litigation
matters, neither we nor any of our direct or indirect subsidiaries is a party to, nor is any of our property the subject of, any
legal proceedings other than ordinary routine litigation incidental to their respective businesses. There are no proceedings pending
in which any of our officers, directors or 5% shareholders are adverse to us or any of our subsidiaries or in which they are taking
a position or have a material interest that is adverse to us or any of our subsidiaries.



Page 95 of 132







From time to time, we may be involved in
litigation relating to claims arising out of our operations in the normal course of business.



Indemnities and Guarantees



The Company has executed certain contractual
indemnities and guarantees, under which it may be required to make payments to a guaranteed or indemnified party. The Company has
agreed to indemnify its directors, officers, employees and agents to the maximum extent permitted under the laws of the State of
Delaware. In connection with a certain facility lease, the Company has indemnified its lessor for certain claims arising from the
use of the facilities. Pursuant to various Sale and Purchase Agreements, the Company has indemnified the holders of registrable
securities for any claims or losses resulting from any untrue, allegedly untrue or misleading statement made in a registration
statement, prospectus or similar document. Additionally, the Company has agreed to indemnify the former owners of JPI against losses
up to a maximum of $2,500,000 for damages resulting from breach of representations or warranties in connection with the original
JPI acquisition. The duration of the guarantees and indemnities varies, and in many cases is indefinite. These guarantees and indemnities
do not provide for any limitation of the maximum potential future payments the Company could be obligated to make. Historically,
the Company has not been obligated to make any payments for these obligations and no liabilities have been recorded for these indemnities
and guarantees in the accompanying consolidated balance sheets.



NOTE 11 — SHARE-BASED COMPENSATION



The Company has seven share-based compensation
plans under which it may grant common stock or incentive and non-qualified stock options to officers, employees, directors and
independent contractors. The exercise price per share under the incentive stock option plan shall not be less than 100% of the
fair market value per share on the date of grant. The exercise price per share under the non-qualified stock option plan shall
not be less than 85% - 100% of the fair market value per share on the date of grant. All options granted under the plans through
December 31, 2011 had an exercise price equal to the fair market value at the date of grant. The expiration date of options granted
under any of the plans may not exceed 10 years from the date of grant.



Effective June 30, 1999, the Company adopted
the 1999 Stock Option Plan (the “1999 Plan”). The Company can grant options for the purchase of up to 16,000 shares
of the Company’s common stock under the 1999 Plan. The 1999 Plan terminated on June 30, 2009, after which grants cannot be
made from the 1999 Plan. All options vest upon grant and expire five years from the date of grant. As of December 31, 2011 there
are no options outstanding under the 1999 Plan.



On January 25, 2002, the board of directors
adopted the 2002 Stock Option Plan (the “2002 Plan”). The Company can grant options for the purchase of up to 8,000
shares of the Company’s common stock under the 2002 Plan. All options granted vest upon grant and expire five years from
the date of grant. As of December 31, 2011, there were no options outstanding under the 2002 Plan. The Company had 1,569 options
available for grant under the 2002 Plan at December 31, 2011.



On February 23, 2004, the board of directors
adopted the 2004 Stock Option Plan (the “2004 Plan”). The Company can grant options for the purchase of up to 19,200
shares of the Company’s common stock under the 2004 Plan. The Company had 14,360 options available for grant and there are
no options outstanding under the 2004 Plan.



On March 14, 2006, the board of directors
adopted the 2006 Equity Incentive Plan (the “2006 Plan”). The Company can grant options for the purchase of up to 40,000
shares of the Company’s common stock under the 2006 Plan. Vesting of grants under the 2006 Plan is determined at the discretion
of the Compensation Committee of the board of directors. Options granted under the 2006 Plan have generally vested upon grant.
As of December 31, 2011, 12,880 options at a weighted average exercise price of $62.95 per share were outstanding under the 2006
Plan. The Company had 5,720 options available for grant under the 2006 Plan at December 31, 2011.



On September 7, 2006, the Company’s
shareholders approved the 2007 Equity Incentive Plan (the “2007 Plan”). The Company can grant options for the purchase
of up to 60,000 shares of the Company’s common stock under the 2007 Plan. Vesting of grants under the 2007 Plan is determined
at the discretion of the Compensation Committee of the board of directors. Options granted under the 2007 Plan generally vest ratably
over 24 months. As of December 31, 2011, 30,000 options at a weighted average exercise price of $45.75 per share were outstanding
under the 2007 Plan. The Company had 26,600 options available for grant under the 2007 Plan at December 31, 2011.



Page 96 of 132







On December 3, 2010, the Company’s
shareholders approved the 2010 Equity Incentive Plan (the “2010 Plan”). The 2010 Plan provides for the grant to employees,
including executive officers, of restricted common stock, as well as cash or other share-based awards and other benefits. A maximum
of 240,000 shares of common stock may be issued and awarded under the 2010 Plan; however, as of January 1 of each year, commencing
with the year 2011 and ending with the year 2013, the aggregate number of shares available for granting awards under the 2010 Plan
shall automatically increase by a number of shares equal to the lesser of (x) 5% of the total number of shares of the Company’s
common then outstanding or (y) 40,000. The maximum number of shares of common stock that may be subject to stock awards granted
to any one participant during any single year period is 120,000. Vesting of grants under the 2010 Plan is determined at the discretion
of the Compensation Committee of the board of directors. Options granted under the 2010 Plan generally vest immediately upon grant.
As of December 31, 2011, 219,000 options at a weighted average exercise price of $9.75 per share were outstanding under the 2010
Plan. The Company had 16,400 options available for grant under the 2010 Plan at December 31, 2011.



Our board of directors approved the 2011
Stock Option Plan (the “2011 Plan”) via unanimous written consent on October 3, 2011 and our shareholders approved
it at the November 4, 2011 Special Shareholder Meeting. The Compensation Committee or our board of directors may suspend or terminate
the 2011 Plan at any time.



The 2011 Plan provides for the grant to
employees, including executive officers, consultants and directors of restricted common stock, as well as cash or other stock-based
awards and other benefits. The purpose of the 2011 Plan is to enable us to attract and retain qualified persons as employees, officers
and directors and others, whose services are required by us, and to motivate such persons by providing them with equity participation
in us.



Under the 2011 Plan, an aggregate of up
to 10% of the total fully diluted issued and outstanding shares of common stock may be issued and awarded, up to a maximum of not
more than 20 million shares of common stock.



The 2011 Plan is administered by the Compensation
Committee, which has, subject to specified limitations, the full authority to grant equity awards and establish the terms and conditions
for vesting and exercise thereof. Awards of restricted stock under the 2011 Plan may qualify for the “performance-based compensation”
exception under the Internal Revenue Code of 1986 (the “IRC”) Section 162(m) pursuant to their expected terms. Cash-based
awards and awards of restricted stock, performance units and stock may qualify under Section 162(m) of the IRC if the terms of
the award state, in terms of an objective formula or standard, the method of computing the amount of compensation payable under
the award and preclude discretion to increase the amount of compensation payable under the terms of the award.



For further information about the 2011
Plan, please see the Definitive Information Statement on Schedule 14A that we filed with the SEC on October 14, 2011.



As of December 31, 2011, 13,040,000 options
were granted under the 2011 Plan by the compensation committee on November 4, 2011; 10,600,000 of which were granted to our executive
officers and directors, 1,640,000 of which were granted to key employees, and 800,000 of which were granted to our outside securities
counsel.  All such options were granted at an exercise price equal to $0.11 per share, being the greater of $0.11 or
100% of the closing price of our common stock as at November 4, 2011.



The Company had 6,960,000 options available
for grant under the 2011 Plan at December 31, 2011.



Summary of Assumptions and Activity



The fair value of option awards to employees,
directors and consultants are calculated using the Black-Scholes option pricing model, even though the model was developed to estimate
the fair value of freely tradable, fully transferable options without vesting restrictions, which differ significantly from the
Company’s stock options. The Black-Scholes model also requires subjective assumptions, including future stock price volatility
and expected time to exercise, which greatly affect the calculated values. The expected volatility is based on the historical volatility
of the Company’s stock price. The expected term of options granted is derived from historical data on employee exercises
and post-vesting employment termination behavior. The risk-free rate selected to value any particular grant is based on the U.S.
Treasury rate that corresponds to the expected term on the date of the grant. The Company does not expect to pay dividends in the
foreseeable future, thus the dividend yield is zero. These factors could change in the future, affecting the determination of share-based
compensation expense in future periods.



Page 97 of 132







Under the 2011 Plan, stock
options granted to directors, officers and outside counsel vest immediately upon grant and stock options granted to employees vest
over a term of twelve months. Stock options granted under the 2010 Plan vest immediately upon grant.



During the years ended December 31, 2011
and 2010, the Company granted an aggregate of 13,040,000 and 223,600, respectively, of stock options to employees, directors, and
outside consultants. The Company used the Black-Scholes option pricing model to value the options. The options were valued at $1,321,817
and $1,844,700 on November 4, 2011 and December 3, 2010, respectively, the date of grant. The Company used the following assumptions
in valuing the options on the grant date:



|                        |  | November 4, 2011 |       |  | December 3, 2010 | 
|----------------------- |  | ---------------- | ----- |  | ---------------- | 
|Annual dividend yield   |  |                  | -     |  |                  | 
|Expected life (years)   |  |                  | 5     |  |                  | 
|Risk-free interest rate |  |                  | 0.88c/o |  |                  | 
|Expected volatility     |  |                  | 156c/o  |  |                  | 



Share-based compensation expense recognized
during the period is based on the value of the portion of share-based payment awards that is ultimately expected to vest during
the period. ASC 718-10 requires estimates of forfeitures of unvested options at the time of grant. Estimated forfeitures are revised
in subsequent periods if actual forfeitures differ from those estimates. The estimated average forfeiture rate for 2011 and 2010
was 0%, as options generally vest upon grant.



During September 2009, the Company modified
various employee stock options to change the exercise price to $18.75. For the fully vested options, this modification resulted
in $129,360 of expense recorded during the year ended December 31, 2009. During the year ended December 31, 2010, the Company recorded
$173,758 as additional expense related to the remaining vested employee and director stock options.



Employee and director share -based compensation
expense for the years ended December 31, 2011 and 2010, including expense related to the modification of options upon the retirement
of our former Chief Executive Officer, as described above, was $1,102,190 and $2,018,458, respectively. Share-based compensation
related to employee and director stock options under ASC 718-10 is included in selling, general and administrative expense. As
of December 31, 2011, there was $138,534 of unrecognized employee stock option expense which will be amortized in subsequent periods
over the vesting term.



The following is a status of all stock options outstanding at
December 31, 2011 and 2010 and the changes during the years then ended:



|                                               |  | 2011    |            |   | 2010     |  
|---------------------------------------------- |  | ------- | ---------- | - | -------- | -
|                                               |  |         |            |   | Weighted |  
|                                               |  |         |            |   | Average  |  
|                                               |  |         |            |   | Exercise |  
|                                               |  | Options |            |   | Price    |  
|                                               |  |         |            |   |          |  
|Outstanding and exercisable, beginning of year |  |         | 294,720    |   |          |  
|                                               |  |         |            |   |          |  
|Granted                                        |  |         | 13,040,000 |   |          |  
|                                               |  |         |            |   |          |  
|Expired/forfeited                              |  |         | (32,840    | ) |          |  
|                                               |  |         |            |   |          |  
|Outstanding and expected to vest, end of year  |  |         | 13,301,880 |   |          | $
|                                               |  |         |            |   |          |  
|Vested and exercisable, end of year            |  |         | 11,935,213 |   |          | $



Page 98 of 132







There were no options exercised in 2011
or 2010. The aggregate intrinsic value of options outstanding at December 31, 2011 and 2010, considering only options with positive
intrinsic values and based on the closing stock price, was $0 and $3,744,237, respectively. The weighted-average remaining
contractual term of outstanding and exercisable options at December 31, 2011 and 2010 was 4.82 and 4.10 years, respectively.



Share-Based Compensation for Services



During the year ended December
31, 2011 and 2010, the Company recorded an aggregate of $490,417 and $427,410, respectively of consulting expense related to the
amortization of prepaid consulting expenses.



During the year ended December
31, 2011 and 2010, the Company recorded an aggregate of $587,140 and $2,795,179 of consulting expense related to the vesting of
common stock shares issued to consultants for services (see Note 13).



During the year ended December
31, 2011, the Company recorded an aggregate of $2,466,398 of consulting expense related to the fair value of common stock issuable
to consultants for services in accordance with terms of the respective agreements. As of December 31, 2011, an aggregate fair value
of $1,816,996 shares of common stock remains issuable when the Company has sufficient authorized shares and is included in accounts
payable and accrued expenses in the accompanying consolidated balance sheet as of December 31, 2011 (see Note 16).



On November 4, 2011, the
Company recorded an aggregate of $81,093 related to the fair value of stock options granted to legal counsel that vest immediately
on date of grant. Such stock options were accounted for as derivative liabilities due to insufficient shares upon the exercise
of such options. The Company used the Black-Scholes option pricing model to compute the fair value of the stock options on date
of grant. See above for details of assumptions used.



NOTE 12 — STOCK WARRANTS



The Company issues warrants pursuant to
debt financings, consulting, and service agreements.



On September 10, 2009, the Company issued
to a consultant, in connection with the Bridge Loan Agreement, a five-year warrant to purchase 8,000 shares of the Company’s
common stock at an exercise price of $15.00 per share. The warrant was valued at $88,000 using the Black-Scholes option pricing
model with a discount rate of 2.38% and a volatility of 97.27% and recorded as a prepaid asset. During the years ended December
31, 2011 and 2010 the Company recorded amortization expense of $0 and $58,667 related to this agreement, respectively. The warrant
was exercised on January 19, 2011, and the Company received gross proceeds in aggregate of $56,000 which excludes commission payments
of $10,080 for net cash proceeds of $45,920. The aggregate intrinsic value of the warrants exercised was $50,345.



On November 30, 2009, in connection with
the closing of the 2009 Registered Direct Offering (“RDO”) of shares of common stock and warrants, the Company issued
warrants to purchase 68,417 shares of its common stock to the purchasers in that offering at an initial exercise price of $31.25
per share, subject to adjustment as provided in the warrant. In December 2010, the Company issued additional warrants pursuant
to the anti-dilution provisions of the RDO warrants. Accordingly, the exercise price of such warrants was reduced to $7.00 and
the number of warrants was increased by 227,901 for an aggregate total of 293,686 shares.



In connection with the First, Second, Third,
and Fourth Closing of the convertible note purchase agreements effective March 22, 2010, April 8, 2010, April 13, 2010 and April
26, 2010, (see Note 8 for further information), the Company issued warrants to purchase up to 525,947 shares of the Company’s
common stock at a minimum exercise price at issuance date ranging between $7.00 and $22.25 per share subject to adjustment as provided
in the warrant.



In May 2010, the Company entered into separate
arrangements with the former 2008 Convertible Debt holders to issue additional warrants to purchase 44,586 additional shares of
the Company’s common stock (see Note 8 for further information) and a modification of the exercise price ranging from $28.25
to $41.00.



On May 27, 2010, the Company granted a
four-year warrant to purchase 16,000 shares of the Company’s common stock at an exercise price of $30.75 per share to be
earned over a 2 year period. The warrants were valued using the Black-Scholes option pricing model using an expected term of 4
years, volatility of 130.01%, risk free interest rate of 2.18% and a zero dividend rate. As a result of the valuation, the Company
recorded $400,000 as prepaid consulting and amortized $200,002 and $116,669, as of December 31, 2011 and 2010, respectively. As
of December 31, 2011, the remaining prepaid balance to be amortized in subsequent periods was in amount of $83,329.



Page 99 of 132







During the year ended December 31, 2010,
St. George, a convertible debt holder, exercised outstanding warrants to purchase an aggregate of 20,000 Shares of the Company’s
common stock. All warrants exercised during the year ended December 31, 2010 by St. George were at $7.00 per share, the adjusted
warrant exercise price pursuant to the terms of the warrants. The total net proceeds from the exercise of warrants by St. George
during such period were $140,000. The aggregate intrinsic value of the warrants exercised was $16,000.



During the year ended December 31, 2010,
note holder of Senior Notes Series 1 and 2, exercised outstanding warrants to purchase an aggregate of 29,920 shares of the Company’s
common stock. The warrants were exercised at the contractual exercise prices between $24.50 and $24.75 per share. The total gross
proceeds from the exercise of warrants by Senior Notes Series 1 and 2 note holders during such period were $740,800 before commission
of $62,312. The aggregate intrinsic value of the warrants exercised was $486,200.



In October 2010, five holders of warrants
issued in connection with the September 2008 convertible notes (see Note 8) exercised warrants to purchase an aggregate of 4,234
shares of the Company’s common stock. As a result of private negotiations during October 2010, we re-priced these warrants
held by 5 of the investors to $13.00 per share. The original price of the warrants that were re-priced was $92.00, $118.50 and
$67.25. The remaining unexercised warrants remain exercisable at their original exercise price as set forth above. The total gross
proceeds from the exercise of warrants by the 2008 convertible note holders were $55,045. The aggregate intrinsic value of the
warrants exercised was $8,468.



In October 2010, the note holder of the
warrants issued in connection with the First Closing of convertible notes (see Note 8) exercised warrants to purchase 44,000 shares
of the Company’s common stock. The warrants were exercised using the cashless-exercise option of the warrants.



In January 2011, two note holder of Senior
Notes Series 1 and 2 exercised outstanding warrants to purchase 8,000 shares of the Company’s common stock for $56,000.



During the year ended December 31, 2011,
holders of warrants issued in connection with the 2010 Convertible Debt closings exercised 735,356 of warrants using the cashless
exercise provision. The Company issued 965,527 shares of its common stock in exchange for the warrants.



In January 2011, as part of the Debt Exchange
agreement with the Series 1 and Series 2 Senior Notes (see Note 8), an aggregate of 157,248 warrants previously issued to the note
holders, the placement agent warrants, and the Bridge Loan warrants were re-priced from the original exercise price ranging from
$24.50 to $28.25 to an exercise price of $7.00. The Company revalued the warrants based on the Black-Scholes option pricing model
for the difference in value of the warrants immediately before the modification and the fair value immediately after the modification.
Accordingly, the Company recorded to interest expense an aggregate of $485,246 during the year ended December 31, 2011.



In January 2011, in relation to the January
2011 Notes, an aggregate of 877,332 warrants were issued to the note holders and placement agents (see Note 8) with an exercise
price ranging from $16.75 to $20.44. The warrants were valued using the Binomial Lattice model. In July 2011, the warrants issued
to note holders were cancelled and exchange with new warrants. The warrants were valued using the Binomial Lattice model and an
aggregate of $2,109,375 was reclassified from derivative liabilities to equity during the year ended December 31, 2011. In November
2011, the July warrants issued to note holders were cancelled and exchanged with new warrants. All these warrants are adjustable
due to contractual down round provisions (See Note 16). The warrants were valued using the Binomial Lattice model and an aggregate
of $273,958 was reclassified from derivative liabilities to equity during the year ended December 31, 2011.



On August 1, 2011, first determination
date, the exercise price for 33,582 Placement Agent warrants issued in connection with January 2011 financing was reduced to $1.25
per share.  The adjustment is effective August 15, 2011 and was made pursuant to the original contractual agreement and
is calculated on the first day the securities may be resold without restriction or limitation pursuant to Rule 144. If the arithmetic
average of the Weighted Average Prices for each of the ten (10) Trading Days immediately following the First Determination Date
(the "First Adjustment Price") is less than the then existing Exercise Price, then on the tenth (10th) Trading Day following
the First Determination Date, the Exercise Price then in effect shall be reduced (but in no event increased) to the First Adjustment
Price. The warrants are accounted for as derivatives and the modification of the exercise price was captured though the binomial
valuation process and recorded as a change in fair value of derivative liabilities.



Page 100 of 132







On November 30, 2011, the Company received
cash consideration for exercise of Series B warrants issued in connection with 2011 November Exchange (See Note 8). This transaction
triggered two adjustments to the 33,582 Placement Agent warrants: the exercise price was reduced to $0.055825, and the number of
the warrants was increase to 751,950.



On September 6, 2011, the exercise price
for the 24,445 warrants outstanding in connection with Second and Fourth of 2010 Closings was adjusted to $0.23.  The
adjustment was made pursuant to the down round provisions of the original contractual agreement and was triggered by September
6, 2011 second Pre-installment for the 2011 Exchange Notes. (See Note 8). The warrants are accounted for as derivatives and the
modification of the exercise price was captured though the binomial valuation process, with the effect recorded in change in fair
value for the period.



During the year ended December 31, 2011,
principal and interest of the 2008 Convertible Debt was converted to equity (see Note 8). As a result of the 50% warrant coverage
feature of the notes, the Company issued 10,367 warrants with an exercise price of $38.75 per share.



The following represents a summary of the
warrants outstanding at December 31, 2011 and 2010 and changes during the years then ended:



|                                               |  | 2011     |             |   | 2010     |  
|---------------------------------------------- |  | -------- | ----------- | - | -------- | -
|                                               |  |          |             |   | Weighted |  
|                                               |  |          |             |   | Average  |  
|                                               |  |          |             |   | Exercise |  
|                                               |  | Warrants |             |   | Price    |  
|                                               |  |          |             |   |          |  
|Outstanding and exercisable, beginning of year |  |          | 1,085,547   |   |          | $
|                                               |  |          |             |   |          |  
|Granted                                        |  |          | 322,866,422 |   |          |  
|                                               |  |          |             |   |          |  
|Expired/forfeited                              |  |          | (4,679,766  | ) |          |  
|                                               |  |          |             |   |          |  
|Exercised                                      |  |          | (751,356    | ) |          |  
|                                               |  |          |             |   |          |  
|Outstanding and exercisable, end of year       |  |          | 318,520,847 |   |          | $



Page 101 of 132









The following table summarizes information about warrants outstanding
at December 31, 2011:



|Exercise Price  |  | Number of Warrant Shares (1) |             |  | Weighted Average Remaining Contractual Life (Years) | 
|--------------- |  | ---------------------------- | ----------- |  | --------------------------------------------------- | 
|                |  |                              |             |  |                                                     | 
|$0.06 - $0.18   |  |                              | 318,258,000 |  |                                                     | 
|$7              |  |                              | 166,223     |  |                                                     | 
|$16.50          |  |                              | 16,145      |  |                                                     | 
|$28.25 - $30.00 |  |                              | 14,174      |  |                                                     | 
|$30.25 - $39.25 |  |                              | 32,324      |  |                                                     | 
|$40.50 - $42.75 |  |                              | 27,087      |  |                                                     | 
|$67.25          |  |                              | 6,894       |  |                                                     | 
|                |  |                              | 318,520,847 |  |                                                     | 



| | (1) | Includes certain warrants which can be exercised for no consideration under the cashless exercise
provisions as defined in the warrant agreements (see Note 8).
| | --- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------



The outstanding warrants at December 31,
2011 and 2010 are held by consultants and other service providers, stockholders, and current and former note-holders and are immediately
exercisable.



NOTE 13 — STOCKHOLDERS’ DEFICIT



Preferred Stock



The Company’s Certificate of
Incorporation authorizes the Company to issue up to 25,000,000 shares of $0.001 par value preferred stock. Shares of
preferred stock may be issued in one or more classes or series at such time and in such quantities as the board of directors
may determine. During the year ended December 31, 2011, the Company issued 670,100 shares of preferred stock Series A which
were exchanged in June 2011 with 402,411 shares of preferred stock Series B and 50,000 shares of preferred stock Series C. In
accordance with relevant accounting guidance, the Series B and Series C Preferred Stock are treated as liabilities since the
amount of shares of common stock convertible into is not fixed (See Note 8). As of December 31, 2011, an aggregate of 395,602
shares of preferred stock Series B and 50,000 shares of preferred stock Series C were outstanding.



On January 30, 2011 we sold our convertible
promissory notes in a private placement to five accredited investors (the “2011 Noteholders”).  We closed
the financing on January 31, 2011, and received approximately $7,500,000 in gross proceeds and net proceeds after transaction expenses
were approximately $6,820,000.  In connection with the closing of the financing, we issued an aggregate principal amount
of $8,437,500 of convertible notes, at a purchase price of $888.88 for each $1,000 of principal amount of notes, which were initially
convertible into an aggregate of 562,500 shares of our common stock at an initial conversion price of $15.00 per share.  In
addition, the investors also received: (i) 5 year Series A Warrants (the “Original Series A Warrants”) to purchase
an aggregate of 562,500 shares of our common stock at an initial exercise price of $16.75 per share and (ii) 5 year Series
B Warrants (the “Original Series B Warrants”) to purchase an aggregate of 281,250 shares of our common stock at an
initial exercise price of $20.44 per share for their investment.



In May 2011 we defaulted in the performance
of certain of our covenants under the January 2011 Notes.  On June 29, 2011, we entered into an exchange agreement with
each of the 2011 Noteholders in order to settle our obligations to such 2011 Noteholders. Pursuant to the exchange agreement, each
2011 Noteholder exchanged their claims for note and covenant violations on July 1, 2011 (effective date), for (i) our 4% $4,950,000
aggregate amount of convertible notes (the “4% Notes”)), (ii) shares of our aggregate stated value  $6,701,000
of 4% Series A Convertible Preferred Stock (the “Series A Preferred Stock”), and (iii) a five year warrant to
purchase additional shares of our common stock.  On August 26, 2011, we further amended the 4% Notes to change the related
installment payment dates under the 4% Notes, and additional waivers were given with respect to the automatic conversion dates
under the Series A Preferred Stock.  Additionally, the maturity date of the 4% Notes was changed to December 8, 2011,
and waivers were given with respect to the Series A Preferred Stock so that the final automatic conversion would occur on December
8, 2011.



Page 102 of 132







Due to the occurrence of various events
of defaults under the 4% Notes and triggering events under the Series A Preferred Stock as well as significant decreases in the
market value of our common stock, we sought to restructure the terms of the securities issued to the 2011 Noteholders.  Accordingly,
on November 28, 2011, we entered into separate exchange agreements with each of the 2011 Noteholders (the “November 2011
Exchange Agreements”), under which each 2011 Noteholders agreed to exchange all of their securities we issued to them under
the June 29, 2011, exchange agreements for the Radient securities as described in Note 8.





The Series B Preferred Stock is convertible
at the holders’ option. RPC may be required to redeem the Series B Preferred upon the occurrence of a trigger event, which
includes RPC being in default on the November Notes. The Series B Preferred shares convert into a variable number of common shares.
Therefore, RPC has concluded that liability classification is more appropriate. The stated value of $10/share is a mutually agreed
upon value that represents the amount RPC owes to the preferred shareholders. Because the Series B Preferred Stock is to be classified
as a liability, RPC has determined that the fair value of the liability related to the Preferred Stock should be equal to its stated
value of $4,024,410 (see Note 8).



The Series C Preferred Stock has the same
terms as the Series B and should be accounted in the same manner with their $500,000 stated value recorded as a liability (see
Note 8).



The conversion features of both the Series
B & C Preferred Stock have met all three criteria that are required for bifurcation in accordance with ASC 815-10, and as such,
are treated as derivative instruments.



Common Stock



The Company’s Certificate of Incorporation authorizes
the Company to issue up to 5,000,000,000 shares of common stock, $0.001 par value.



The Company has funded its operations primarily
through a series of Regulation S and Regulation D companion offerings (the “Offerings”), which consisted of the issuance
of common stock or debt and equity securities that are convertible or exercisable into shares of our common stock.



Common Stock Issued for Services



On January 22, 2009, the Company granted
B&D Consulting 16,000 shares of the Company’s common stock in exchange for services, vesting over a period of 24 months.
A total of 667 and 8,000 of common stock shares were vested during the years ended December 31, 2011 and 2010, respectively. In
accordance with relevant accounting guidance, the shares are valued as they are earned monthly, as such, the Company recorded general
and administrative expense of $10,167 and $137,638, for the years ended December 31, 2011 and 2010, respectively related to this
agreement.



On September 10, 2009, the Company entered
into a consulting agreement (the “Consulting Agreement”) with Cantone Asset Management, LLC (“Cantone Asset”)
whereby Cantone Asset provided guidance and advice related to negotiating the terms of the Company’s outstanding Series 1
and Series 2 Senior Notes and continued services to assist the Company to coordinate with the holders of the Series 1 and Series
2 Senior Notes (see Note 8). We agreed to increase the cash fee owed to Cantone Asset by 25% to a total owed of $180,000, and instead
of paying the amount owed in cash we agreed to issue them 25,714 shares of the Company’s common stock as full payment of
the amount owed, subject to NYSE Amex approval. NYSE Amex approved the shares on January 3, 2011 and the shares were issued in
January 2011. The expense of $180,000 for the consulting agreement was recorded to general and administrative expense in the accompanying
condensed consolidated statement of operations for the year ended December 31, 2011.



On January 7, 2010, the Company entered
into an agreement for the issuance of 4,000 shares of common stock to Boston Financial Partners for financial advisory services
to be provided for the period January 1, 2010 through July 1, 2010. The shares vest ratably over the seven month period. The issuance
of the shares was contingent upon NYSE Amex Approval. NYSE Amex Approval was received in April 8, 2010. Therefore, the shares for
compensation were measured and recorded on the date the Company received NYSE Amex approval and the Company recorded prepaid consulting
of $71,000 related to the agreement. The shares were earned during the year ended December 31, 2010, and the Company recorded general
and administrative expense of $71,000 related to the agreement.



On January 13, 2010, the Company entered
into an agreement with B&D Consulting for investor relations services through June 13, 2010. The Company granted B&D Consulting
8,000 shares of the Company’s common stock in exchange for services. In accordance with FASB ASC 505-50, the shares issued
are periodically valued, as earned, through the vesting period. The shares were earned during the year ended December 31, 2010,
and the Company recorded general and administrative expense of $108,000 related to the agreement.



On January 13, 2010, the Company entered
into an agreement with Catawaba LTD (“Catawaba”) for investor relations services through September 13, 2010. The Company
granted Catawaba 36,000 shares of the Company’s common stock in exchange for services which were valued at $288,000 and was
recorded as prepaid consulting expense. The prepaid consulting expense was amortized to consulting expense ratably over the service
period. During the year ended December 31, 2010, the Company amortized $288,000 related to the consulting agreement, as general
and administrative expenses related to the agreement.



Page 103 of 132







On February 5, 2010, the Company entered
into an agreement for the issuance of 19,200 shares of common stock to Garden State Securities pursuant to a consulting agreement
for consulting services to be provided from February 5, 2010 through February 5, 2011. The issuance of the shares was contingent
upon NYSE Amex Approval. NYSE Amex approval was received on April 8, 2010. In accordance with FASB ASC 505-50, the shares issued
are periodically valued, as earned, through the vesting period. The Company recorded $85,200 as prepaid consulting expenses for
the initial 4,800 shares that were to be vested over three months and the remaining shares were expensed when earned. During the
years ended December 31, 2011, and 2010, 373 and 18,827, respectively, shares were earned. The Company recorded general and administrative
expense of $7,466 and $352,440 during the years ended December 31, 2011, and 2010, respectively, related to the agreement.



On February 9, 2010, the Company entered
into an agreement for the issuance of 36,000 shares of common stock to LWP1 pursuant to a consulting agreement for financial advisory
services to be provided from February 9, 2010 through November 9, 2010. The shares vested over a ten month period as follows: 18,000
on February 9, 2010 and 2,000 each month thereafter, through the vesting term. The issuance of the shares was contingent upon NYSE
Amex approval. NYSE Amex Approval was received on April 8, 2010. In accordance with FASB ASC 505-50, the shares issued are periodically
valued, as earned, through the vesting period. The Company recorded $319,500 as prepaid consulting expenses for the initial 18,000
shares that were to be vested over three months and the remaining shares were expensed when earned. During the year ended December
31, 2010, all 36,000 shares were earned. The Company recorded general and administrative expense of $670,333 during the year ended
December 31, 2010 related to the agreement.



On February 22, 2010, the Company agreed
to issue 6,429 shares of common stock to settle an unpaid invoice in the amount of $45,000 of accounts payable through the date
of the agreement, subject to NYSE Amex Approval. NYSE Amex approval was received on April 8, 2010 and the Company recorded the
common stock issuance of $45,000 based on stock price on such date.



On March 1, 2010, the Company entered into
an agreement for the issuance of 28,800 shares of common stock to JFS Investments pursuant to a consulting agreement for financial
advisory services to be provided through February 28, 2011. The issuance of the shares was contingent upon NYSE Amex approval.
NYSE Amex approval was received on April 8, 2010. In accordance with FASB ASC 505-50, the shares issued are periodically valued,
as earned, through the vesting period. The Company recorded $127,800 as prepaid consulting expenses for the initial 7,200 shares
that were to be vested over three months and the remaining shares were expensed when earned. During the years ended December 31,
2011 and 2010, 2,960 and 25,840 respectively, shares were earned. The Company recorded general and administrative expense of $47,600
and $472,260 during the year ended December 31, 2011 and 2010, respectively, related to the agreement.



On April 13, 2010, the Company entered
into an agreement with Lyons Consulting for investor relation services through October 2010. The Company granted Lyons Consulting
8,000 shares of the Company’s common stock in exchange for services. The shares were approved by the NYSE Amex US on October
15, 2010, at which time the Company valued the shares at $16.50 per share. The Company recorded general and administrative expense
of $132,000 during the year ended December 31, 2010 related to the agreement.



On May 10, 2010, the Company entered into
an agreement with Uptick Marketing for marketing services through August 2010. The Company granted Uptick Marketing 10,000 shares
of the Company’s common stock in exchange for services. The shares were approved by the NYSE Amex US on October 15, 2010,
at which time the Company valued the shares at $16.50 per share. The Company recorded general and administrative expense of $165,000
during the year ended December 31, 2010 related to the agreement.



On August 1, 2010, the Company entered
into an agreement with Catawaba Global LTD (“Catawaba”) for investor relations services through May 1, 2011. The Company
granted Catawaba 8,000 shares of its common stock in exchange for services. The shares were approved by the NYSE Amex US on December
3, 2010. The shares and were valued at $78,000 and recorded as prepaid consulting expense. The prepaid consulting expense was amortized
to consulting expense ratably over the service period. During the year ended December 31, 2011 and 2010 the Company amortized $34,667
and $43,333, respectively, related to the consulting agreement.



On August 1, 2010, the Company entered
into an agreement with First International Capital Group, LTD (“First International”) for investor relations services
through Feb 1, 2011. The Company granted First International 8,000 shares of its common stock in exchange for services. The shares
were approved by the NYSE Amex US on December 3, 2010. The shares were valued at $78,000 and recorded as prepaid consulting expense.
The prepaid consulting expense was amortized to consulting expense ratably over the service period. During the years ended December
31, 2011 and 2010, the Company amortized $13,000 and $65,000, respectively, related to the consulting agreement.



Page 104 of 132







On August 1, 2010, the Company entered
into an agreement for the issuance of 19,200 shares of common stock to Garden State Securities pursuant to a consulting agreement
for consulting services to be provided from August 1, 2010 through August 1, 2011. NYSE Amex approval was received on December
3, 2010. During the years ended December 31, 2011 and 2010, 11,200 and 8,000, respectively, shares were earned. The Company recorded
general and administrative expense of $153,287 and $78,000 during the year ended December 31, 2011 and 2010, respectively, related
to the agreement.



On August 1, 2010, the Company entered
into an agreement for the issuance of 28,800 shares of common stock to JFS Investments pursuant to a consulting agreement for consulting
services to be provided from August 1, 2010 through August 1, 2011. NYSE Amex approval was received on December 3, 2010. During
the year ended December 31, 2011 and 2010, 16,800 and 12,000, respectively, shares were earned. The Company recorded general and
administrative expense of $188,620 and $90,000, during the year ended December 31, 2011 and 2010, respectively, related to the
agreement.



On June 1, 2011, as later amended on August
7, 2011, we entered into an agreement for the issuance of 72,000 shares of common stock to JFS Investments pursuant to a consulting
agreement for consulting services to be provided through May 31, 2012. On November 21, 2011, we entered into an amendment agreement
with JFS Investments for investor relations services through October 31, 2012, pursuant to which we would issue them an aggregate
of 4,000,000 shares in exchange for their services. As of December 31, 2011, a total of 2,208,667 shares of common stock were earned
under the terms of the contract and the Company has recorded an aggregate of $440,967 as consulting expense in selling, general
and administrative expenses. In accordance with the agreement and relevant accounting guidance, the remaining 1,863,333 shares
shall be expensed in monthly installments, when the shares are vested and earned in the subsequent periods. On December 15, 2011,
we issued an aggregate of 1,400,000 shares of common stock to consultant. Due to the unavailability of authorized shares,
we issued the balance of 2,672,000 shares on January 6, 2012 (See Note 16 Subsequent Events).



On August 20, 2011, we entered into an
agreement for the issuance of 48,000 shares of common stock to Brighton Capital (“Brighton”) pursuant to a consulting
agreement for consulting services to be provided through July 15, 2011. On November 21, 2011, we entered into an amendment agreement
with Brighton for investor relations services through October 31, 2012, pursuant to which we would issue them an aggregate of 4,000,000
shares in exchange for their services. As of December 31, 2011, a total of 2,214,667 shares of common stock were earned under the
terms of the contract and the Company has recorded an aggregate of $520,167 as consulting expense in selling, general and administrative
expenses. In accordance with the agreement and relevant accounting guidance, the remaining of 1,833,333 shares shall be expensed
in monthly installments, when the shares are vested and earned in the subsequent periods. On December 15, 2011, we issued an aggregate
of 1,448,000 shares of common stock to consultant. Due to the unavailability of authorized shares, we issued the balance of 2,600,000
shares on January 6, 2012 (See Note 16 Subsequent Events).



During the year ended December 31, 2011,
we issued an aggregate of 4,800 shares of common stock to three of our directors as compensation for services provided. The total
fair value of the common stock issued amounted to $31,180 based on the stock price on the date of issue.



Shares Issued in Connection with Conversion of Debt



During the year ended December 31, 2010,
certain 2008 Convertible Debt holders converted their note balance and accrued interest balances of $1,709,738 into 57,575 shares
of our common stock (see Note 8).



During the year ended December 31, 2010,
St. George converted 100% of its note balance and accrued interest of $666,390 and $52,916, respectively into 102,758 shares of
our common stock (see Note 8).



During the year ended December 31, 2010,
ISP Holdings converted an aggregate of $1,862,485 of their Note balance into 148,840 shares of the Company’s common stock
(see Note 8).



During the year ended December 31, 2011,
certain 2008 Convertible Debt holders converted their note balance and accrued interest balances of $371,055 into 19,068 shares
of our common stock (see Note 8).



Page 105 of 132







During the year ended December 31, 2011,
certain 2010 Convertible Debt holders converted 100% of its note balance and accrued interest of $20,212,149 into 5,742,136 shares
of our common stock (see Note 8).



During the year ended December 31, 2011,
certain Senior Notes holders converted their note balance and accrued interest balances of $5,571,999 into 551,367 shares of our
common stock (see Note 8).



During the year ended December 31, 2011,
aggregated principal and interest in the amount of $165,834 of the Bridge Loan was converted into 23,690 shares of the Company’s
common stock (see Note 8).



Conversion of Securities issued pursuant
to the July 2011 Exchange Agreements



During the year ended December 31, 2011,
pursuant to the July 2011 Exchange Agreement, all of the holders of the Company’s Series A Preferred Stock converted a total
of 670,100 shares of Series A Preferred Stock to Series A warrants. In addition, some of the July 2011 note holders have converted
a total of $9,493 dividends accrued from the Series A Preferred Stock,$1,469,392 principal and $7,013 of accrued interest for an
aggregate of 9,949,912 and 7,383,198 shares of common stock pursuant to such conversions, respectively.



Conversion of Securities issued pursuant
to the November 2011 Exchange Agreements



During the year ended December 31, 2011,
since receiving their respective Series B Preferred Stock and November Notes pursuant to each of their respective November 2011
Exchange Agreements, some of the holders have converted a total of approximately 6,839 shares of Series B Preferred Stock, $79
dividends accrued and $41,390 principal, $71 interest accrued of November Notes for an aggregate total issuance of 1,226,558 and
742,705 shares of common stock pursuant to conversions of the Series B Preferred Stock and Note, respectively An aggregate of 40,142
shares of common stock were considered constructively issued as of December 31, 2011 for two conversions of Series B Preferred
Stock.



JPI Debentures Conversion



On February 2, 2011, JPI closed a $900,000
financing (the “Bridge Financing”). In connection with the closing of the Bridge Financing, JPI issued 10% Convertible
Debentures to six accredited investors’ in the aggregate principal amount of $900,000 (the “JPI Debentures”).
As part of the agreement, we secured the JPI Debentures with shares of our common stock in the event that JPI did not complete
a reverse merger or other event, which results in its stock becoming publicly traded on a U.S. equity market within one year
after the closing of the Bridge Financing (the "Going Public Deadline”).  The JPI Debentures could then be
exchanged for shares of our common stock at a conversion price of $7 per share (the “RPC Conversion Price”) unless
a majority of the holders of the Debentures consent in writing to an extension of the Going Public Deadline; provided, however,
that the Going Public Deadline shall not be extended for more than six months in total.   If we were required to so issue
our shares, the maximum dollar value of the shares to be issued is $1,000,000, plus accrued interest. The RPC Conversion Price
is subject to full ratchet anti-dilution protection.



Following the closing, JPI’s board
of directors determined it would be in the best interest of JPI to increase the offering, in the hopes of receiving additional
funding and allowing themselves and the placement agent additional time to achieve the goals of such financing. Accordingly, the
JPI Debentures were amended to extend the Going Public Deadline to September 30, 2011 and to increase the total offering of the
Bridge Financing to $2,000,000 (from $1,000,000). On March 17, 2011, JPI conducted an additional closing of the Bridge Financing
in the amount of $100,000 increasing the aggregate principal amount of the JPI Debentures to $1,000,000, to be used to underwrite
legal and accounting expenses associated with an anticipated merger transaction and reverse merger process for JPI (“proposed
transaction”).



JPI did not meet the Going Public Deadline
and therefore the JPI Debentures automatically converted into shares of our common stock as of September 1, 2011 at a conversion
rate of $0.25, pursuant to the adjustment terms contained in the JPI Debenture. The adjustment terms of the JPI Debenture require
a full adjustment whenever we issue securities at a price less than $7, which we have since done at a price of $0.25. Due to our
authorized capital limitation, we were unable to issue the shares until December 2011, after we received shareholder approval to
increase our authorized capital. On or around December 23, 2011, we issued an aggregate of 4,346,333 shares of our common stock
to the holders of JPI convertible debentures as per the automatic exchange provision contained therein, for conversion of the $1
million guarantee and associated interest of $86,583. Following such issuance, the JPI Debentures are fully converted.



Page 106 of 132







Shares Issued in Connection with Warrant
Exercises and Financing Arrangements



During the year ended December 31, 2010,
St. George, a convertible debt holder, exercised outstanding warrants to purchase an aggregate of 20,000 shares of the Company’s
common stock. All warrants exercised during the year ended December 31, 2010 by St. George were at $7.00 per share, the adjusted
warrant exercise price pursuant to the terms of the warrants. The total net proceeds from the exercise of warrants by St. George
during such period were $140,000. The aggregate intrinsic value of the warrants exercised was $16,000.



During the year ended December 31, 2010,
note holders of Senior Notes Series 1 and 2, exercised outstanding warrants to purchase an aggregate of 29,920 shares of the Company’s
common stock. The warrants were exercised at the contractual exercise prices between $24.50 and $27.75 per share. The total gross
proceeds from the exercise of warrants by Senior Notes Series 1 and 2 note holders during such period were $740,800 before commission
of approximately $62,312. The aggregate intrinsic value of the warrants exercised was $486,200.



In October 2010, five holders of warrants
issued in connection with the September 2008 convertible notes (see Note 8) exercised warrants to purchase an aggregate of 4,234
shares of the Company’s common stock. The warrants were exercised at the re-priced amount of $13.00 per share . The total
gross proceeds from the exercise of warrants by the 2008 convertible note holders were $55,045. The aggregate intrinsic value of
the warrants exercised was $8,468.



In October 2010, ISP Holdings exercised
44,000 warrants into the same number of our common shares through a cashless exercise. All of these shares were previously approved
by NYSE Amex for issuance. The aggregate intrinsic value of the warrants exercised was $0.



On September 10, 2009, the Company issued
to a consultant, in connection with the Bridge Loan Agreement, a five-year warrant to purchase 8,000 shares of the Company’s
common stock at an exercise price of $15.00 per share. The warrant was exercised on January 19, 2011, and the Company received
gross proceeds in aggregate of $56,000 which excludes commissions paid of $10,080 for net cash proceeds of $45,920. The aggregate
intrinsic value of the warrants exercised was $50,345.



In January 2011, two note holder of Senior
Notes Series 1 and 2 exercised outstanding warrants to purchase 8,000 shares of the Company’s common stock for $56,000.



During the year ended December 31, 2011,
holders of warrants issued in connection with the 2010 Convertible Debt closings exercised 735,356 of warrants using the cashless
exercise provision. The Company issued 965,527 shares of its common stock in exchange for the warrants.



Legal Settlement
and True-Up Shares



As previously disclosed, Alpha Capital
Anstalt (“Alpha Capital”) and Whalehaven Capital Fund Ltd (‘Whalehaven”, and together with Alpha Capital,
collectively the "Plaintiffs") filed a complaint against us regarding the number of warrants Plaintiffs received in a
registered direct offering we completed in November 2009 and the shareholder vote we obtained at our December 3, 2010 annual shareholder
meeting. As later reported, on May 10, 2011, we entered into a Settlement Agreement with the Plaintiffs pursuant to which we agreed
to issue that number of shares of our common stock equal in value to $10,912,055 at the time of issuance, which shares were evidenced
in part by convertible promissory notes issued to the Plaintiffs. Such Settlement Agreement, as amended on May 23, 2011 (the “Original
Settlement Agreement”), was approved by the United States District Court for the Southern District of New York (the “Court”)
which issued an order providing that the common stock issuable under the notes were exempt securities under Section 3(a)(10) of
the Securities Act of 1933, as amended. As further reported, on July 19, 2011 the Plaintiffs wrote a letter to the Court that we
failed to perform our obligations under the Original Settlement Agreement, which allegations we have been disputed. Pursuant thereto,
to avoid litigation, on August 25, 2011, we entered into new settlement agreement with Plaintiffs that amended and restated the
Original Settlement Agreement (the “Final Settlement Agreement”), which was approved by the Court on August 26, 2011.
Under the terms of the Final Settlement Agreement, we issued our 8% convertible promissory notes in the principal amount of $4,559,842.41
to Alpha Capital and $3,496,415.91 to Whalehaven (the “Notes”). (For a complete discussion of the Final Settlement
Agreement and Notes, please see the Current Report on Form 8-K that we filed on August 29, 2011.)



Based on the available amount of shares
the NYSE Amex previously approved for the Plaintiffs, upon Court Approval on May 24, 2011, we issued the Plaintiffs an aggregate
of 20,000 sharesof our common stock valued at $140,400 and issued promissory notes for an aggregate amount of $10,771,655.
As a result of this agreement, we recorded legal settlement expense of $10,987,055.



Page 107 of 132







Pursuant to the settlement and convertible
notes agreements, in June 2011 we issued the Plaintiffs an aggregate of 820,000 shares of our common stock. On or about June 23,
2011, we advised Plaintiffs that due to the fact that each of the convertible notes held by Whalehaven and Alpha Capital are, by
their stated terms, immediately convertible at the option of the holders into more than ten percent (10%) of the issued and outstanding
shares of common stock of the Company, each of the Plaintiffs is an affiliate of the Company as defined in Rule 144(a) promulgated
under the Securities Act. As such, any additional Settlement Shares issued to the Plaintiffs under the Settlement Agreement would
have to comply with the applicable provisions of the Securities Act and specifically Rule 144 promulgated thereunder with regard
to resales. Accordingly we advised plaintiffs that the additional 820,000 shares issued to Plaintiffs pursuant to Section 3(a)(10)
may only be resold in compliance with Rule 144. These shares are not “restricted securities” within the meaning of
Rule 144(a); they are not subject to the holding period limitations of Rule 144(d). However, they are subject to the other relevant
provisions of Rule 144, including (i) the limitation of the amount of securities that may be sold by an affiliate pursuant to Rule
144(e)(1) and the manner of sale pursuant to Rule 144(f).



Additionally, we agreed to issue Plaintiffs
additional Non-Restricted Shares (the “True Up Shares”) to adjust, based on the recent reductions in the closing prices
of our publicly trades shares, the number of shares we previously issued to the Plaintiffs in connection with prior conversions
of the notes we issued under the Original Settlement Agreement. We agreed to reserve an aggregate of 7 million shares of authorized
and previously unissued Common Stock for potential issuance to the Plaintiffs for issuance upon their conversion of the Notes.
We further agreed to keep a sufficient number of shares of Common Stock for purposes of enabling issuing all of the Settlement
Shares pursuant to the Final Settlement Agreement and the Notes. As of December 31, 2011, we have issued a total of 3,720,000 True-Up
Shares to Alpha Capital and 2,196,000 True-Up Shares to Whalehaven. As of December 31, 2011, an aggregate of 44,400,232 shares
are issuable to Plaintiffs, as follow: 24,758,988 True-Up Shares to Alpha Capital and 19,641,945 True-Up Shares to Whalehaven (See
Note 16 Subsequent Events).



Pursuant to the Final Settlement Agreement
we were released from all liability and claims from Plaintiffs arising under the Original Settlement Agreement.



NOTE 14 — SEGMENT REPORTING



After the deconsolidation of JPI on September 29, 2009, the
Company has one reportable segment, Corporate, which is comprised of the In-vitro diagnostics business.



The following table presents net revenues
by geographic region for the Corporate reportable segment for the year ended December 31, 2011 and 2010:



|                                      |  | 2011   |         |  | 2010       | 
|------------------------------------- |  | ------ | ------- |  | ---------- | 
|                                      |  | Amount |         |  | Percentage | 
|Net revenues made in the U.S.         |  | $      | 81,456  |  |            | 
|                                      |  |        |         |  |            | 
|Net revenues made outside of the U.S. |  |        | 232,103 |  |            | 
|                                      |  |        |         |  |            | 
|                                      |  | $      | 313,559 |  |            | 



NOTE 15 — RELATED PARTY TRANSACTIONS



During the year ended December 31, 2010,
Minghui (“Henry”) Jia, a member of our board of directors, paid for certain JPI expenses, totaling approximately $120,000
for which we reimbursed him.



NOTE 16 — SUBSEQUENT EVENTS



Subsequent events have been evaluated through
the date that the consolidated financial statements were issued. Except as disclosed below, there are no reportable subsequent
events.



Page 108 of 132







On April 27, 2011, we entered into an
agreement with Catawaba Global LTD (“Catawaba”) for investor relations services through December 31, 2011. We
granted Catawaba 30,000 shares of our common stock in exchange for services. On November 21, 2011, we entered into an
amendment agreement with Catawaba Global LTD (“Catawaba”) for investor relations services through October 31,
2012, pursuant to which we would issue them an aggregate of 1,400,000 shares in exchange for their services. On January 6,
2012, the Company issued 1,430,000 shares of common stock, of which 1,138,333 shares were vested as of June 15, 2012. In
accordance with the agreement and relevant accounting guidance, the remaining 291,667 shares shall be expensed in monthly
installments, when the shares are vested and earned in the subsequent periods. As of June 15, 2012, the Company has recorded an aggregate of $476,156 as
consulting expense in selling, general and administrative expenses for the vested shares.



On May 1, 2011, we entered into an agreement
with First International Capital Group, LTD (“First International”) for investor relations services through December
31, 2011. We granted First International 30,000 shares of our common stock in exchange for services. On November 21, 2011, we entered
into an amendment agreement with First International Capital Group, LTD (“First International”) for investor relations
services through October 31, 2012, pursuant to which we would issue them an aggregate of 1,400,000 shares in exchange for their
services. On January 6,
2012, the Company issued 1,430,000 shares of common stock, of which 1,138,333 shares were vested as of June 15, 2012. In
accordance with the agreement and relevant accounting guidance, the remaining of 291,667 shares shall be expensed in monthly installments,
when the shares are vested and earned in the subsequent periods. As of June 15, 2012 the Company has recorded an aggregate of $476,156 as consulting expense in selling,
general and administrative expenses for the vested shares.



On June 1, 2011, we entered into
an agreement for the issuance of 32,000 shares of our common stock to Garden State Securities pursuant to a consulting
agreement for consulting services to be provided through December 31, 2011. On November 21, 2011, we entered into an
amendment agreement with Garden State Securities for investor relations services through October 31, 2012, pursuant to which
we would issue them an aggregate of 3,000,000 shares in exchange for their services. On January 4, 2012, the Company issued
3,032,000 of common stock, of which 2,407,000 shares were vested as of June 15, 2012. In accordance with the agreement and
relevant accounting guidance, the remaining of 625,000 shares shall be expensed in monthly installments, when the shares are
vested and earned in the subsequent periods. As of June 15, 2012, the Company has recorded an aggregate of $465,338 as consulting expense in selling,
general and administrative expenses  for the vested shares.



On June 1, 2011, as later amended
on August 7, 2011, we entered into an agreement for the issuance of 72,000 shares of common stock to JFS Investments pursuant
to a consulting agreement for consulting services to be provided through May 31, 2012. On November 21, 2011, we entered into
an amendment agreement with JFS Investments for investor relations services through October 31, 2012, pursuant to which we
would issue them an aggregate of 4,000,000 shares in exchange for their services. As of June 15, 2012, an aggregate of
4,072,000 shares were issued, of which 2,672,000 shares were issued on January 6, 2012, and 3,220,667 shares of common stock
were vested. In accordance with the agreement and relevant accounting guidance, the remaining of 851,333 shares shall be
expensed in monthly installments, when the shares are vested and earned in the subsequent periods. As of June 15, 2012 the
Company has recorded an aggregate of $628,450 as consulting expense in selling, general and administrative expenses for the
vested shares.



Page 109 of 132







On August 1, 2011, we entered into
an agreement for the issuance of 12,000 shares of common stock to Galileo Asset Management (“Galileo”) pursuant
to a consulting agreement for consulting services to be provided through December 31, 2011. On November 21, 2011, we entered
into an amendment agreement with Galileo for investor relations services through October 31, 2012, pursuant to which we
would issue them an aggregate of 400,000 shares in exchange for their services. In January 2012, the Company issued an
aggregate of 412,000 shares of common stock, of which 328,667 shares were vested as of June 15, 2012. In accordance with the
agreement and relevant accounting guidance, the remaining of 83,333 shares shall be expensed in monthly installments, when
the shares are vested and earned in the subsequent periods. As of June 15, 2012, the Company has recorded an aggregate of
$67,428 as consulting expense in selling, general and administrative expenses  for the vested shares.



On August 20, 2011, we entered into
an agreement for the issuance of 48,000 shares of common stock to Brighton Capital (“Brighton”) pursuant to a
consulting agreement for consulting services to be provided through July 15, 2011. On November 21, 2011, we entered into an
amendment agreement with Brighton for investor relations services through October 31, 2012, pursuant to which we would issue
them an aggregate of 4,000,000 shares in exchange for their services. As of June 15, 2012, an aggregate of 4,048,000 have
been issued, of which 2,600,000 shares were issued on January 6, 2012, and 3,214,667 shares of common stock were vested.
In accordance with the agreement and relevant accounting guidance, the remaining of 833,333 shares shall be expensed in
monthly installments, when the shares are vested and earned in the subsequent periods. As of June 15, 2012, a total of
3,214,667 shares of common stock were earned under the terms of the contract and the Company has recorded an aggregate of
$555,200 as consulting expense in selling, general and administrative expenses.



As of the date of this filing, both
Alpha Capital and Whalehaven have been issued an aggregate of 44,400,233 True-up shares owed to them.



In January 2012, the Company issued
948,234 shares of common stock to St. George in connection with the conversion of the 2010 convertible debt.



In January 2012, the Company issued
10,000 shares to Cantone Asset Management for consulting services.



In May 2012, the Company issued an
aggregate of 2,680,412 shares of common stock to Alpha Capital and Whalehaven for the exercise of warrants.



In June 2012, the Company issued an
aggregate of 151,741,750 shares of common stock to Alpha Capital and Whalehaven for the conversion of notes.



From January 1, 2012 through June
15, 2012, the Company issued an aggregate of approximately 1.1 billion shares of common stock to the 2011 Note holders for
the conversion of Notes, Preferred Stock and exercise of warrants.



We filed a Registration Statement on December
30 2011, as amended on January 26, 2012 and February 14, 2012. We seek registration of 16 million warrants issued in connection
with the November 2011 Exchange Transaction (see Note 8). On February 14, 2012, the Registration Statement was declared effective.



We received a notice from the Pink OTC
Markets Inc., dated August 23, 2011 notifying us that we were out of compliance with OTCQX Rules for U.S. Companies section 3.2.b,
which states, in essence, that our common stock must have a minimum closing bid price of $0.10 per share at least once in every
thirty consecutive trading days. If our common stock does not meet that requirement, we have 180 days to regain compliance therewith
by maintaining a $0.10 closing bid price for ten consecutive trading days during such grace period. The grace period ended on February
20, 2012 and because our common stock did not meet the closing bid price requirement, our common stock was moved  from the
OTCQX tier of the OTC Markets to the OTCQB tier of the OTC Markets, as of February 22, 2012. The main difference between the OTCQB
and OTCQX is that stocks listed on the OTCQX undergo additional quality review and have different listing standards than those
on the OTCQB, although both are tiers of the OTC Markets. Our trading symbol shall remain the same.



The delisting of our common stock from
the OTCQX constitutes an event of default under certain of our outstanding notes, including the 2011 Noteholders. As of June 15,
2012, such notes have a total outstanding balance of approximately $12.9 million. Under the default provisions of such notes, the
holders maintain the right to accelerate the payment of the entire outstanding balance of their notes. In addition, the 2011 Noteholders
have the right to demand redemption of all of their outstanding Series B and C Preferred Stock. As of June 15, 2012 , an aggregate
of 338,078 and 50,000 shares of Series B and C Preferred Stock is outstanding, respectively.



We have a severe working capital shortage
and are currently unable to pay our accounts payable and other obligations in the ordinary course of business. As of June 15, 2012,
approximately $1.3 million of our accounts payable is overdue. Although we are actively seeking to obtain additional financing,
there can be no assurance that such financing will be available or, if so, that such financing will be on terms that would be beneficial
to us or our shareholders.



Page 110 of 132







On March 22, 2012, one of our directors,
Mr. Robert L. Rooks informed us that due to changes in his outside work schedule and commitments, he tendered his resignation as
a member of our board of directors and all positions he held on our board committees, effective immediately. Mr. Rooks is not resigning
due to any disagreements with us.



Between March 26, 2012 and April 3, 2012,
we received an Event of Default Redemption Notice and a Notice of Redemption from four note holders. Pursuant to the Event of Default
Redemption Notice, each note holder elected to redeem their respective note in full, thereby requiring immediate payment of the
entire outstanding balance of their note. Failure to pay the balance by April 2, 2012, will activate the late charges of 24% per
annum until the redemption price is paid in full. Pursuant to the Notice of Redemption, each note holder elected to redeem all
of their respective shares of Series B Preferred Stock and Series C Preferred Stock at the current redemption price, which must
be paid by April 2, 2012. Failure to pay by April 2, 2012 triggers interest payments at the rate of 2% per month for each unredeemed
share until the redemption price is paid in full.



These same four note holders also asserted
claims against the Company's officers and directors for breaches of fiduciary duties of care, loyalty, good faith and disclosure,
self dealing and waste and spoliation of corporate assets. Pursuant thereto, the note holders asserted damages in amounts equal
to at least $4.25 million or $2.25 million, respectively.



Due to the absence of any working capital,
we are unable to pay the redemption prices at this time. The Company has appointed a committee of our remaining three independent
directors to assess available options open to the Company to enable us to continue operations at this time.



As previously disclosed in our recent
filings, we have been experiencing severe working capital shortages. In addition, substantially all of the holders have declared
defaults and demanded repayment of these obligations. Unfortunately, our attempts to raise additional funds to resolve our capital
shortages and cure defaults in payment and performance of our obligations have been unsuccessful to date



As a result of our working capital
deficiencies, we have recently laid off a substantial portion of our work force and are currently operating on a minimal
basis with only two  employees and three former employee consultants. The current focus of our operations is to ensure that
our existing Onko-Sure® customers and any future customers are able to place orders and receive kits on a timely basis.
We have an Onko-Sure® production continuity arrangement in place with one vendor. At the current time, the Company
believes that it does not require any additional staff to perform this limited manufacturing, quality control and selling
process.



In addition to our inability to
pay our existing obligations, we were unable to pay  our auditors and therefore had been unable to file our Annual Report
on Form 10K for the year ended December 31, 2011, which was due by April 16, 2012 (extension deadline). We were also unable
to file our Quarterly Report on Form 10Q for the quarter ended March 31, 2012, which was due by May 21, 2012
(extension deadline). As stated elsewhere in this Report, we received funds to file this Report and the Quarterly Report on
Form 10Q for the quarter ended March 31, 2012 and are working diligently to file such report by the contractual deadline to
do same.



The committee of our three independent
directors continues to assess whether the Company has any other options to remain in business. Due to the
shortage of working capital, we were unable to pay premiums associated with our Directors and Officers insurance. As
a consequence, on June 25, 2012, we were informed by two members of our Board of Directors of their resignation. As a result,
we have only one independent Director serving on our Board at this time. Although our remaining sales team
continues to work towards completing pending and future sales of our Onko-Sure ® test kit, if these sales are not completed
and we do not otherwise raise additional funds in the immediate future, it is likely that we will be forced to cease all operations
and might seek protection from our creditors under the United States bankruptcy laws.



Page 111 of 132







On May 17, 2012, we completed an
agreement with the 2011 Noteholders (“May 2012 Agreement”), severally and not jointly, for the exercise of an
aggregate of $150,000 worth of our Series A Common Stock Purchase Warrants at an exercise price of $0.02619 per share. The
proceeds received from such Warrant exercise, shall be used solely and exclusively to enable us to keep our Registration
Statement on Form S-1 filed under the Securities Act of 1933, as amended, which the Securities and Exchange Commission
declared effective on February 14, 2012, current and maintain compliance with our reporting requirements under the Securities
Exchange Act of 1934, as amended.



As a condition to the exercise of the
Warrants, we agreed that following the date of the May 2012 Agreement and through and including 5:00 p.m. (EDT) on August 31,
2012, we will not file in any U.S. Bankruptcy Court a voluntary petition for reorganization under Chapter 11 of Title 11 of
the United States Code or seek to liquidate under Chapter 7 of such Code. Additionally, each of the 2011 Noteholders,
severally and not jointly, agreed to forebear from exercising any of their rights and remedies, whether at law or in equity,
against us and our current and former directors and officers for a period that shall not exceed the earlier to occur of (i)
August 31, 2012, or (ii) a breach by us of any of our other covenants and agreements contained in the prior agreements with
the 2011 Noteholders or in the current May 2012 Agreement, including, without limitation, our commitment to file with the SEC
this 2011 Form 10-K by June 30, 2012 and our March 31, 2012 Form 10-Q by July 15, 2012. The 2011 Noteholders further agreed
that in the absence of a further breach of the terms of the May 2012 Agreement or any of the other agreements between us and
the 2011 Noteholders, that each of the previously issued default notices shall be deemed to be withdrawn ab initio upon
execution of the May 2012 Agreement.



Additionally, as part of the May 2012
Agreement and in order to provide for payment of past due legal fees, we issued to our legal counsel, Hunter Taubman
Weiss LLP, a $300,000 unsecured  4% convertible note that matures on April 30, 2015, which shall (i) accrue
interest at the rate of 4% per annum, (ii) be convertible into our Common Stock at a fixed conversion price of $0.01 per
share, (iii) be subject to prepayment at the option of the Company, (iv) contain full ratchet and other customary
anti-dilution protection, and (v) not be subject to any mandatory installment or other mandatory prepayment provisions prior
to the April 30, 2015 maturity date.



If, in the near future, we are unable to
complete the additional financing and satisfy the investor’s cash payment conditions, or we are unable to obtain alternative
financing, we may have to seek protection from creditors under the Federal Bankruptcy Act. Our inability to pay our debts as they
become due also constitutes an event of default under our senior notes and a mandatory redemption event under our redeemable Series
B Preferred Stock.



Item 9. Changes in and Disagreements With Accountants on
Accounting and Financial Disclosure



None.



Item 9A. Controls and Procedures



Disclosure Controls and Procedures



Our management, with the participation
of our Chief Executive Officer and Chief Financial Officer, has evaluated the effectiveness of our disclosure controls and procedures
as of December 31, 2011 (as such term is defined in Rules 13a-15(e) and 15d-15(e) under the Securities Exchange Act of 1934, as
amended (the “Exchange Act”). Based on this evaluation, our Principal Executive Officer and our Principal Financial
Officer concluded that our disclosure controls and procedures, subject to the limitations as noted below, were not effective during
the period and as of the end of the period covered by this annual report to ensure that information required to be disclosed by
us in reports that we file or submit under the 1934 act is recorded, processed, summarized and reported within the time periods
specified in the SEC rules and forms and that such information is accumulated and communicated to our management as appropriate
to allow timely decisions regarding required disclosures.



Because of inherent limitations, our disclosure
controls and procedures may not prevent or detect misstatements. A control system, no matter how well conceived and operated, can
provide only reasonable, not absolute, assurance that the objectives of the controls system are met. Because of the inherent limitations
in all controls systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud,
if any, have been detected.



Page 112 of 132







Management’s Report on Internal Control Over Financial
Reporting



Our internal controls over financial reporting
are designed by, or under the supervision of our Chief Executive Officer and Chief Financial Officer or persons performing similar
functions, and effected by our board of directors, audit committee, management and other personnel, to provide reasonable assurance
regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance
with generally accepted accounting principles. Our internal control over financial reporting includes those policies and procedures
that:



| | · | Pertain to the maintenance of records
that in reasonable detail accurately and fairly reflect the transactions and dispositions of our assets;
| | - | ----------------------------------------------------------------------------------------------------------------------------------------------



| | · | Provide reasonable assurance that transactions
are recorded as necessary to permit preparation of financial statements in accordance with accounting principles generally accepted
in the United States and that our receipts and expenditures are being made only in accordance with authorizations of our management
and directors; and
| | - | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | Provide reasonable assurance regarding
prevention or timely detection of unauthorized acquisition or disposition of our assets that could have a material effect on the
financial statements.
| | - | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Because of its inherent limitations, the
Company’s internal control over financial reporting may not prevent or detect misstatements. Therefore, even those systems
determined to be effective can provide only reasonable assurance with respect to financial statement preparation and presentation.
Projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because
of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate.



Our management assessed the effectiveness
of our internal control over financial reporting as of December 31, 2011. In making this assessment, management used the criteria
set forth by the Committee of Sponsoring Organizations of the Treadway Commission (COSO) in Internal Control — Integrated
Framework.



A material weakness is a control
deficiency (within the meaning of the Public Company Accounting Oversight Board (“PCAOB”) Auditing Standard No.
5) or combination of control deficiencies, that result in more than a remote likelihood that a material misstatement of the
annual or interim financial statements will not be prevented or detected. Management has identified the following four
material weaknesses which have caused management to conclude that, as of December 31, 2011, our internal control over
financial reporting was not effective at the reasonable assurance level:



| | a) | We do not have sufficient segregation of duties within accounting functions, which is a basic internal
control. Due to our size and nature, segregation of all conflicting duties may not always be possible and may not be economically
feasible. However, to the extent possible, the initiation of transactions, the custody of assets and the recording of transactions
should be performed by separate individuals.
| | -- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------





| | b) | We did not maintain effective controls to ensure there is adequate analysis, documentation, reconciliation,
and review of accounting records and supporting data.
| | -- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------



| | c) | We did not maintain adequate controls in place to identify and approve non-recurring transactions
such that the validity and proper accounting can be determined on a timely basis.
| | -- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------





| | d) | We did not maintain sufficient accounting resources with adequate training in the application of
GAAP commensurate with our financial reporting requirements. The complexity of our operations and transactions, specifically related
to the accounting and reporting of debt and equity transactions, including derivative instruments resulted in significant audit
adjustments during the year ended December 31, 2011.
| | -- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Page 113 of 132







To address these material weaknesses, management
performed additional analyses and other procedures to ensure that the consolidated financial statements included herein fairly
present, in all material respects, our financial position, results of operations and cash flows for the periods presented. We are
attempting to remediate the material weaknesses in our disclosure controls and procedures and internal controls over financial
reporting (“ICFR”) identified above by refining our internal procedures, and adding staff members and / or outside
professionals with appropriate levels of experience and expertise (see below).



Remediation of Material Weakness



As of December 31, 2011, there were control
deficiencies which constitute material weaknesses in our internal control over financial reporting. To the extent reasonably possible
in our current financial condition, we:



| | 1. | Added staff members and outside consultants with appropriate levels of experience and accounting
expertise to the finance department to ensure that there is sufficient depth and experience to implement and monitor the appropriate
level of control procedures.
| | -- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | 2. | Issued policies and procedures regarding the delegation of authority.
| | -- | ---------------------------------------------------------------------



| | 3. | We are in the process of strengthening our internal policies and enhancing our processes for ensuring
consistent treatment of complex derivative valuation and the validation of our conclusions regarding significant accounting policies
and their application to our business transactions are carried out by personnel with an appropriate level of accounting knowledge,
experience, and training.
| | -- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Through these steps, we believe we are
addressing the deficiencies that affected our internal control over financial reporting as of December 31, 2011. Because the remedial
actions require hiring of additional personnel, upgrading certain of our information technology systems, and relying extensively
on manual review and approval, the successful operation of these controls for at least several quarters may be required before
management may be able to conclude that the material weakness has been remediated. We intend to continue to evaluate and strengthen
our ICFR systems. These efforts require significant time and resources including financial resources that we do not currently have;
therefore, we are unable to fully execute these plans at this time.



Notwithstanding the material weaknesses
discussed above, our management has concluded that the consolidated financial statements included in this Annual Report on Form
10-K fairly present in all material respects our financial condition, results of operations, and cash flows for the years ended
December 31, 2011 and 2010 in conformity with accounting principles generally accepted in the United States of America.



Inherent Limitations Over Internal Controls



Because of its inherent limitations, internal
control over financial reporting may not prevent or detect all errors or misstatements and all fraud. Therefore, even those systems
determined to be effective can provide only reasonable, not absolute, assurance that the objectives of the policies and procedures
are met. Also, projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become
inadequate because of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate.



Our Audit Committee, Board of Directors
and management discussed these weaknesses and we have assigned the highest priority to their correction. In 2011, we plan to continue
to add financial resources and expertise, both through internal hiring and using outside consultants that will provide hands-on
oversight of the monthly financial closing, data analysis, and account reconciliation.



This annual report does not include an
attestation report of our independent registered public accounting firm regarding internal control over financial reporting. Management’s
report was not subject to attestation by our independent registered public accounting firm pursuant to the rules of the SEC that
permit us to provide only management’s report in this annual report.



Page 114 of 132







Changes in Internal Control Over Financial
Reporting



Except as noted above, there have not been
any changes in our internal control over financial reporting (as such term is defined in Rules 13a-15(f) and 15d-15(f) under the
Exchange Act) during the year ended December 31, 2011 that have materially affected, or are reasonably likely to materially affect,
our internal control over financial reporting.



Item 9B. Other Information



We have previously disclosed all information
required to be disclosed on a Form 8-K during the fourth quarter of fiscal 2011 and therefore there is no information to include
here.



PART III



Item 10. Directors, Executive Officers, and CorporateGovernance



The following table and text set forth
the names and ages of all directors and executive officers as of June 29, 2012. The size of our board is currently set at five
and is divided into three classes. Under our Bylaws, at the 2011 annual stockholder meeting, the term of office of the Class I
directors was to expire and the Class I directors were to be elected for a full term of three years; the term of the Class II and
Class III directors are set to expire in 2011 and 2012, respectively. There are no family relationships among our directors and
executive officers. Also provided herein are brief descriptions of the business experience of each director, executive officer
and advisor during the past five years and an indication of directorships held by each director in other companies subject to the
reporting requirements under the Federal securities laws. None of our officers or directors is a party adverse to us or has a material
interest adverse to us.



In May 2010, one of our former Class III
directors, Dr. Arquilla passed away and in June our remaining board of directors approved the appointment of Robert W. Beart, Jr.,
M.D. as one of our directors. Additionally in December 2010, our remaining Class III director, Mr. Thompson resigned from our board
of directors. In February 2011, our remaining board of directors appointed Robert L. Rooks to fill the vacancy.



On August 19, 2011, the Board of Directors
approved appointing Leonard M. J. Reyno, M.D. as a Class I Director, effective on August 22, 2011. Dr. Reyno replaced Minghui Jia,
who resigned from the Company’s Board of Directors effective August 19, 2011.



On March 22, 2012, one of our directors,
Mr. Robert L. Rooks informed us that due to changes in his outside work schedule and commitments, he tendered his resignation as
a member of our board of directors and all positions he held on our board committees, effective immediately. Mr. Rooks is not resigning
due to any disagreements with us.



On June 25, 2012, two of our
directors, Dr. Leonard Reyno and Dr. Robert Beart, informed us of their resignation due to working capital shortages
that prevented us from paying premiums associated with our Directors and Officers Insurance and the consequential
cancellation of same. Neither Dr. Reyno nor Dr. Rooks resigned due to any disagreements with us.



|                     |  |     |  | Year First |  |                                               
|-------------------- |  | --- |  | ---------- |  | ----------------------------------------------
|Name                 |  | Age |  | Elected    |  | Position(s)                                   
|                     |  |     |  |            |  |                                               
|Douglas C. MacLellan |  | 57  |  | 1992       |  | Executive Chairman and Chief Executive Officer
|Akio Ariura          |  | 54  |  | 2006       |  | Chief Financial Officer and Secretary         
|Michael Boswell      |  | 43  |  | 2008       |  | Director                                      



Mr. MacLellan,
in November 2008, was appointed Chairman and CEO. He was originally appointed to the Board in 1992 and became
Chairman of the Audit and Governance committees in 2001. Since November 2009 through the present, Mr. MacLellan has been a
director of China Net Online Holdings, Inc., (NASDAQ:CNET), a leading Chinese media development, advertising, and
communications company. Mr. MacLellan is also serving as the Chairman of Innovare Products, Inc, a privately-held consumer
products company.  Mr. MacLellan is also currently President and CEO of MacLellan Group, Inc., a privately held business
incubator and financial advisory firm since May 1992.  From August 2005 to May 2009, Mr. MacLellan was a member of
the Board of Directors of Edgewater Foods, International, Inc.  Mr. MacLellan was, until September 2005,
formally vice-chairman of the Board of Directors of AXM Pharma, Inc. (AXMP.PK) and its predecessors.  AXM is a
China based bio-pharmaceutical company.  From January 1996 through August 1996, Mr. MacLellan was also the
Vice-Chairman of Asia American Telecommunications (Metromedia China Corporation), a majority owned subsidiary of Metromedia
International Group, Inc.  From November 1996 until March 1998, Mr. MacLellan was co-Chairman and investment
committee member of the Strategic East European Fund.  From November 1995 until March 1998, Mr. MacLellan was
President, Chief Executive Officer and a director of PortaCom Wireless, Inc., a company engaged as a developer and operator
of cellular and wireless telecommunications ventures in selected developing world markets.  Mr. MacLellan is a
former member of the Board of Directors and co-founder of FirstCom Corporation, an international telecommunications company
that operates a competitive access fiber and satellite network in Latin America, which became AT&T Latin America, Inc.
in August 2000.  From 1993 to 1995, Mr. MacLellan was a principal and co-founder of Maroon Bells Capital
Partners, Inc., a U.S. based merchant bank, which specializes in providing corporate finance services to companies in the
international and domestic telecommunications and media industries.  Mr. MacLellan was educated at the University
of Southern California in economics and finance, with advanced training in classical economic theory.



Page 115 of 132







Mr. Ariura
was appointed as our Chief Financial Officer as of August 21, 2006. From September 2004 until joining the Company, Mr. Ariura
was employed by Resources Global Professionals, providing both public and private companies with consulting services on Sarbanes-Oxley
compliance, SEC filings and special project financial and management services in connection with preparation of financial statements,
tax reporting and mergers and acquisitions. From January 2001 to December 2003, Mr. Ariura was Vice President of
Sunvest Industries, LLC in charge of preparation of financial statements, budgets and other financial reports. In light of Mr.
Ariura’s financial and regulatory experience, we determined that he should serve as the company’s Chief Financial Officer.
Mr. Ariura received a B.S. in Business Administration from University of Southern California in 1980. Mr. Ariura has
had no prior affiliation or relationship with the Company.



Mr. Boswell
was elected to the Board in 2008. Mr. Boswell is currently Chairman of the Audit Committee. Mr. Boswell
is President, COO and Chief Compliance Officer for TriPoint Global Equities, LLC, a FINRA member firm that maintains,
specialty practices in institutional private placements, mergers and acquisitions and corporate finance. He provides
high-level financial services to start-up businesses and small-to-mid-sized companies including holding executive and CFO
positions with client companies. Mr. Boswell is also Managing Director of TriPoint Capital Advisors, LLC a merchant bank
and financial advisory affiliate of TriPoint Global. With TriPoint Capital Advisors he has assisted numerous companies
by providing high-level advice regarding corporate finance, corporate structure, corporate governance, mergers and
acquisitions, SOX 404 compliance, implications of various SEC rules and FASB Emerging Issues Task Forces issues as they
relate to private placements, SEC reporting and disclosure requirements, employee option programs, and the overall reverse
merger process. Prior to the founding of TriPoint Global, Mr. Boswell had a number of executive positions focusing
on business development and management consulting. He also spent eight years as a senior analyst and/or senior engineer
for various branches of the United States Government. Mr. Boswell earned a MBA from John Hopkins University and a BS
degree in Mechanical Engineering from University of Maryland; he holds the Series 24, 62, 63, 82 and 99 licenses.



Page 116 of 132







Communications with Directors



Stockholders may communicate with the Chairman
of the Board, the directors as a group, the non-employee directors or an individual director directly by submitting a letter in
a sealed envelope labeled accordingly and with instruction to forward the communication to the appropriate party. Such letter should
be placed in a larger envelope and mailed to the attention of our Secretary at Radient Pharmaceuticals Corporation, 2492 Walnut
Avenue, Suite 100, Tustin, California 92780. Shareholders and other persons may also send communications to members of our Board
who serve on the Audit Committee by utilizing the webpage on our website, http://www.amdl.com, designated for that purpose. Communications
received through the webpage are reviewed by a member of our Audit Committee. Communications that relate to functions of our Board
or its committees, or that either of them believes requires the attention of members of our Board, are provided to the entire Audit
Committee and reported to our Board by a member of the Audit Committee. Directors may review a log of these communications, and
request copies of any of the communications.



Board of Directors Meetings



During the fiscal year ended December 31,
2011, there were twelve meetings of the Board as well as numerous actions taken with the unanimous written consent of the directors.



Section 16(a) Beneficial Ownership Reporting
Compliance



Section 16(a) of the Exchange Act requires
our officers and directors and those persons who beneficially own more than 10% of our outstanding shares of common stock to file
reports of securities ownership and changes in such ownership with the SEC. Officers, directors and greater than 10% beneficial
owners are also required to furnish us with copies of all Section 16(a) forms they file.



Based solely upon a review of the copies
of such forms furnished to us, we believe that during 2011 all Section 16(a) filing requirements applicable to our officers, directors
and persons who own more than 10% of our outstanding shares of common stock were complied with.



Code of Ethics for Financial Professionals



The Company has adopted a Code of Ethics
for Financial Professionals. The Code of Ethics has been posted and may be viewed on our website at: www.radient-pharma.com.



Audit Committee and Financial Expert



We previously had an Audit Committee,
which consisted of Mr. Boswell, Dr. Beart, and Mr. Rooks, each of whom was deemed independent within the meaning of the rules
of the OTC Market and the enhanced independence requirements for audit committee members under Exchange Act Rule 10A-3. The
Audit Committee met six times in 2011. The Audit Committee was established in accordance with Section 3(a)(58)(A) of the
Securities and Exchange Act of 1934. The primary functions of this Committee were to: appoint (subject to
shareholder approval), and be directly responsible for the compensation, retention and oversight of, the firm that will serve
as the Company’s independent accountants to audit our consolidated financial statements and to perform services related
to the audit (including the resolution of disagreements between management and the independent accountants regarding
financial reporting); review the scope and results of the audit with the independent accountants; review with management and
the independent accountants, prior to the filing thereof, the annual and interim financial results (including
Management’s Discussion and Analysis) to be included in Forms 10-K and 10-Q, respectively; consider the adequacy and
effectiveness of our internal accounting controls and auditing procedures; review, approve and thereby establish procedures
for the receipt, retention and treatment of complaints received by Radient regarding accounting, internal accounting controls
or auditing matters and for the confidential, anonymous submission by employees of concerns regarding questionable accounting
or auditing matters; review and approve related person transactions in accordance with the policies and procedures of the
Company; and consider the accountants’ independence and establish policies and procedures for pre-approval of all audit
and non-audit services provided to Radient by the independent accountants who audit its consolidated financial statements.
At each meeting, Committee members may meet privately with representatives of our independent accountants and
with Radient’s Chief Financial Officer.



On March 22, 2012 and June 25, 2012, Mr.
Rooks and Dr. Beart, respectively resigned as members of our Board and from their positions as members of our Audit Committee.
Following Mr. Rooks and Dr. Beart’s resignation, our Audit Committee consists solely of Mr. Boswell.





Page 117 of 132







Mr. Boswell is our Audit
Committee financial expert, as that term is defined in Item 407 of Regulation 5-K. Mr. Boswell’s qualifications as an
Audit Committee financial expert are described in his biography above. As of the date of this Report, Mr. Boswell is not
independent. (See “Director Independence” below)



A current copy of our Audit Committee’s amended and restated
charter is available upon request.



Item 11. Executive Compensation



The following table sets forth all compensation
received during the two years ended December 31, 2011 by our Chief Executive Officer and Chief Financial Officer. Upon Mr. MacLellan’s
appointment in October 2008, we agreed to pay him an annual base salary of $360,000, to be paid in equal monthly installments,
and he is also entitled to certain bonuses subject to our Compensation Committee’s recommendation and approval.



SUMMARY COMPENSATION TABLE



|Name and Principal Position                   |  | Year |      |  | Salary ($) |   |         | Bonus ($) |  |   | Stock Awards ($) |  |  | Option Awards ($)(1) |   |  | Non-Equity Incentive Plan  Compensation Earnings ($) |   |         | Non- qualified Deferred Compensation Earnings ($) |  |   | All Other Compensation ($) |  |  | Total ($) |  
|--------------------------------------------- |  | ---- | ---- |  | ---------- | - | ------- | --------- |  | - | ---------------- |  |  | -------------------- | - |  | ---------------------------------------------------- | - | ------- | ------------------------------------------------- |  | - | -------------------------- |  |  | --------- | -
|Douglas MacLellan, President, CEO, & Chairman |  |      | 2011 |  |            | $ | 345,000 |           |  | $ | -                |  |  | $                    | - |  |                                                      | $ | 506,832 |                                                   |  | $ | -                          |  |  | $         | -
|Douglas MacLellan, President, CEO, & Chairman |  |      | 2010 |  |            | $ | 360,000 |           |  | $ | 238,000          |  |  | $                    | - |  |                                                      | $ | 894,860 |                                                   |  | $ | -                          |  |  | $         | -
|Akio Ariura, CFO                              |  |      | 2011 |  |            | $ | 300,000 |           |  | $ | -                |  |  | $                    | - |  |                                                      | $ | 385,192 |                                                   |  | $ | -                          |  |  | $         | -
|Akio Ariura, CFO                              |  |      | 2010 |  |            | $ | 300,000 |           |  | $ | 144,000          |  |  | $                    | - |  |                                                      | $ | 676,240 |                                                   |  | $ | -                          |  |  | $         | -



| | (1) | Represents the fair value of the options issued during 2010 and 2011.
| | --- | ---------------------------------------------------------------------



Employment Agreements



On November 4, 2008 Douglas C.
MacLellan was appointed as our President and Chief Executive Officer.  Mr. MacLellan does not have an employment
agreement and is compensated at a base salary of $30,000 per month and he participates in the Company’s health
insurance and other benefits available to executive officers.  During the year ended December 31, 2010, Mr.
MacLellan did not earned a bonus.





As a result of severe working capital shortages, during the
period November 2011 through June 30, 2012, Mr. MacLellan did not receive a base salary while remaining as Chief Executive Officer.
Mr. Akio Ariura’s compensation was a base salary of $25,000 per month. Mr. Ariura received $8,000 for the same period while
remaining as the Chief Financial Officer. Due to working capital shortages, health insurance was terminated.



No employment agreement is in effect.



Page 118 of 132







Outstanding Equity Awards at December 31, 2011



|Name              |  | Number of  Securities Underlying Unexercised Options (#) Exercisable |           |  | Number of Securities Underlying Unexercised Options (#)  Unexercisable |  |   | Equity Incentive  Plan Awards: Number of Securities Underlying Unexercised Unearned Options (#) |  |  | Option Exercise  Price ($/Sh) |  |  | Option  Expiration  Date |      
|----------------- |  | -------------------------------------------------------------------- | --------- |  | ---------------------------------------------------------------------- |  | - | ----------------------------------------------------------------------------------------------- |  |  | ----------------------------- |  |  | ------------------------ | -----
|Douglas MacLellan |  |                                                                      | 3,600     |  |                                                                        |  | - |                                                                                                 |  |  | -                             |  |  | $                        | 18.75
|                  |  |                                                                      | 8,000     |  |                                                                        |  | - |                                                                                                 |  |  | -                             |  |  | $                        | 18.75
|                  |  |                                                                      | 100,000   |  |                                                                        |  | - |                                                                                                 |  |  | -                             |  |  | $                        | 9.75 
|                  |  |                                                                      | 5,000,000 |  |                                                                        |  |   |                                                                                                 |  |  |                               |  |  | $                        | 0.11 
|                  |  |                                                                      |           |  |                                                                        |  |   |                                                                                                 |  |  |                               |  |  |                          |      
|Akio Ariura       |  |                                                                      | 2,000     |  |                                                                        |  | - |                                                                                                 |  |  | -                             |  |  | $                        | 18.75
|                  |  |                                                                      | 2,000     |  |                                                                        |  | - |                                                                                                 |  |  | -                             |  |  | $                        | 18.75
|                  |  |                                                                      | 80,000    |  |                                                                        |  | - |                                                                                                 |  |  | -                             |  |  | $                        | 9.75 
|                  |  |                                                                      | 3,800,000 |  |                                                                        |  |   |                                                                                                 |  |  |                               |  |  | $                        | 0.11 



|Name              |  | Number of Shares or Units of Stock That Have Not Vested (#) |   |  | Market Value of Shares or Units of   Stock That Have Not Vested ($) |   |   | Equity Incentive Awards:   Number   of Unearned Shares,   Units, or Other Rights That Have Not Vested (#) |  |  | Equity Incentive Awards:   Market or Payout Value of Unearned Shares,   Units, or Other Rights That Have Not Vested (#) | 
|----------------- |  | ----------------------------------------------------------- | - |  | ------------------------------------------------------------------- | - | - | --------------------------------------------------------------------------------------------------------- |  |  | ----------------------------------------------------------------------------------------------------------------------- | 
|Douglas MacLellan |  |                                                             | - |  |                                                                     | $ | - |                                                                                                           |  |  | -                                                                                                                       | 
|Akio Ariura       |  |                                                             | - |  |                                                                     | $ | - |                                                                                                           |  |  | -                                                                                                                       | 



Page 119 of 132







2010 Performance and Equity Incentive
Plan



On December 3, 2010, our stockholders approved
the 2010 Performance and Equity Incentive Plan (the “2010 Plan”). Under the terms of the 2010 Plan, the Compensation
Committee or our Board of Directors may suspend or terminate the 2010 Plan at any time.



The 2010 Plan provides for the grant to
employees, including executive officers, of restricted common stock, as well as cash or other stock-based awards and other benefits.
The purpose of the 2010 Plan is to enable us to attract and retain qualified persons as employees, officers and directors and others,
whose services are required by us, and to motivate such persons by providing them with equity participation in us.



A maximum of 240,000 shares of common stock
may be issued and awarded under the 2010 Plan; however, as of January 1 of each year, commencing with the year 2011 and ending
with the year 2013, the aggregate number of shares available for granting awards under the 2010 Plan shall automatically increase
by a number of shares equal to the lesser of (x) 5% of the total number of shares of our common then outstanding or (y) 40,000.
The maximum number of shares of common stock that may be subject to stock awards granted to any one participant during any single
year period is 120,000.  As of December 31, 2010, 223,600 options were granted under the 2010 Plan.



The 2010 Plan is administered by the Compensation
Committee, which has, subject to specified limitations, the full authority to grant equity awards and establish the terms and conditions
for vesting and exercise thereof. Awards of restricted stock under the 2010 Plan may qualify for the “performance-based compensation”
exception under the Internal Revenue Code of 1986 (the “IRC”) Section 162(m) pursuant to their expected terms. Cash-based
awards and awards of restricted stock, performance units and stock may qualify under Section 162(m) of the IRC if the terms of
the award state, in terms of an objective formula or standard, the method of computing the amount of compensation payable under
the award and preclude discretion to increase the amount of compensation payable under the terms of the award.



2011 Stock Option Plan



Our Board of Directors unanimously approved
the 2011 Stock Option Plan (the “2011 Plan”) via unanimous written consent on October 3, 2011 and our shareholders
approved it at the November 4, 2011 Special Shareholder Meeting. The Compensation Committee or our Board of Directors may suspend
or terminate the 2011 Plan at any time.



The 2011 Plan provides for the grant to
employees, including executive officers, consultants and directors of restricted common stock, as well as cash or other stock-based
awards and other benefits. The purpose of the 2011 Plan is to enable us to attract and retain qualified persons as employees, officers
and directors and others, whose services are required by us, and to motivate such persons by providing them with equity participation
in us.



Under the 2011 Plan, an aggregate of up
to 10% of the total fully diluted issued and outstanding shares of common stock may be issued and awarded, up to a maximum of not
more than 20 million shares of common stock.



The 2011 Plan is administered by the Compensation
Committee, which has, subject to specified limitations, the full authority to grant equity awards and establish the terms and conditions
for vesting and exercise thereof. Awards of restricted stock under the 2011 Plan may qualify for the “performance-based compensation”
exception under the Internal Revenue Code of 1986 (the “IRC”) Section 162(m) pursuant to their expected terms. Cash-based
awards and awards of restricted stock, performance units and stock may qualify under Section 162(m) of the IRC if the terms of
the award state, in terms of an objective formula or standard, the method of computing the amount of compensation payable under
the award and preclude discretion to increase the amount of compensation payable under the terms of the award.



For further information about the 2011
Plan, please see the Definitive Information Statement on Schedule 14A that we filed with the SEC on October 14, 2011.



As of December 31, 2011, 13,040,000 options
were granted under the 2011 Plan by the compensation committee on November 4, 2011; 10,600,000 of which were granted to our executive
officers and directors, 1,640,000 of which were granted to key employees, and 800,000 of which were granted to our outside securities
counsel.  All such options were granted at an exercise price equal to $0.11 per share, being the greater of $0.11 or
100% of the closing price of our common stock as at November 4, 2011.



Page 120 of 132







Director Compensation



The following table contains information
regarding the compensation of our directors for the fiscal year ended December 31, 2011:



|Name                     |  | Fees Earned or Paid in Cash ($) |         |  | Stock Awards ($) (1) |   |        | Option Awards ($) (2) |  |   | Non-equity Incentive Plan Compensation ($) |  |  | Nonqualified Deferred Compensation Earnings ($) |   |  | All Other Compensation ($) |   |   | Total ($) | 
|------------------------ |  | ------------------------------- | ------- |  | -------------------- | - | ------ | --------------------- |  | - | ------------------------------------------ |  |  | ----------------------------------------------- | - |  | -------------------------- | - | - | --------- | 
|                         |  |                                 |         |  |                      |   |        |                       |  |   |                                            |  |  |                                                 |   |  |                            |   |   |           | 
|Michael Boswell (3)      |  | $                               | 104,000 |  |                      | $ | -      |                       |  | $ | 81,093                                     |  |  | $                                               | - |  |                            | $ | - |           | 
|Robert M. Beart, MD (4)  |  | $                               | 1,750   |  |                      | $ | 15,200 |                       |  | $ | 40,547                                     |  |  | $                                               | - |  |                            | $ | - |           | 
|Dr. Robert Rooks(5)      |  | $                               | 1,393   |  |                      | $ | 15,200 |                       |  | $ | 40,547                                     |  |  | $                                               | - |  |                            | $ | - |           | 
|Dr. Leonard M. Reyno (6) |  | $                               | 12,000  |  |                      | $ | 780    |                       |  | $ | 20,273                                     |  |  | $                                               | - |  |                            | $ | - |           | 



| | (1) | Represents the fair value of the common stock issued in 2011.
| | --- | -------------------------------------------------------------



| | (2) | Represents the fair value of the common stock options granted in 2011.
| | --- | ----------------------------------------------------------------------



| | (3) | Mr.Boswell was elected to the Board in 2008. Currently his compensation is $10,000 monthly.
| | --- | -------------------------------------------------------------------------------------------



| | (4) | When the Board appointed Dr. Beart to serve on our Board, they approved issuing him 1,600 shares
of our common stock and to pay Dr. Beart the same compensation paid to our other independent directors, which is $1,500 for each
in person meeting and $500 for each telephonic meeting he attends. The shares of common stock were issued in May 2011.
| | --- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (5) | When the Board appointed Mr. Rooks to serve on our Board, they approved issuing him 1,600 shares
of our common stock and to pay Mr. Rooks the same compensation paid to our other independent directors, which is $1,500 for each
in person meeting and $500 for each telephonic meeting he attends. The shares of common stock were issued in May 2011. Mr. Rooks
resigned on March 22, 2012.
| | --- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (6) | When the Board appointed Mr. Reyno to serve on our Board, they approved issuing him 1,600 shares
of our common stock and to pay Mr. Reyno $3,000 monthly. The shares of common stock were issued in August 2011.
| | --- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



We indemnify our directors and officers
to the fullest extent permitted by law so that they will be free from undue concern about personal liability in connection with
their service to us. This is permitted by our Certificate of Incorporation and our Bylaws.



Item 12. Security Ownership of Certain Beneficial Owners
and Management and Related Stockholder Matters



Equity Compensation Plan Information



The following provides information concerning compensation plans
under which equity securities of the Company were authorized for issuance as of December 31, 2011:



Page 121 of 132







|Plan Category                                              |  | Number of Securities to be Issued Upon Exercise of Outstanding Options, Warrants and Rights |            |  | Weighted- Average Exercise Price of Outstanding Options, Warrants and Rights |  |      | Number of Securities Remaining Available for Future Issuance Under Equity Compensation Plans (Excluding Securities Reflected in Column (a)) | 
|---------------------------------------------------------- |  | ------------------------------------------------------------------------------------------- | ---------- |  | ---------------------------------------------------------------------------- |  | ---- | ------------------------------------------------------------------------------------------------------------------------------------------- | 
|                                                           |  | (a)                                                                                         |            |  | (b)                                                                          |  |      | (c )                                                                                                                                        | 
|Equity Compensation plans approved by security holders     |  |                                                                                             | 17,317,880 |  |                                                                              |  | 0.40 |                                                                                                                                             | 
|Equity Compensation plans not approved by security holders |  |                                                                                             | -          |  |                                                                              |  | -    |                                                                                                                                             | 
|Total                                                      |  |                                                                                             | 17,317,880 |  |                                                                              |  | 0.40 |                                                                                                                                             | 



SECURITY OWNERSHIP OF CERTAIN BENEFICIAL
OWNERS AND MANAGEMENT



The following table
shows the beneficial ownership of our shares of Common Stock as of June 29, 2012 by (i) each person who is known by us to be the
beneficial owner of more than five percent (5%) of our Common Stock, (ii) each of our directors and executive officers and (iii)
all directors and executive officers as a group. Except as otherwise indicated, the beneficial owners listed in the table have
sole voting and investment powers of their shares.





|Name and Address (1)                              |  | Number of  Shares |           |     | Percentage  Owned (2) | 
|------------------------------------------------- |  | ----------------- | --------- | --- | --------------------- | 
|                                                  |  |                   |           |     |                       | 
|Douglas C. MacLellan                              |  |                   | 5,108,003 | (3) |                       | 
|Akio Ariura                                       |  |                   | 3,882,000 | (4) |                       | 
|Michael Boswell                                   |  |                   |           |     |                       | 
|400 Professional Drive                            |  |                   |           |     |                       | 
|Suite 310                                         |  |                   |           |     |                       | 
|Gaithersburg, MD 20879                            |  |                   | 809,600   | (5) |                       | 
|                                                  |  |                   |           |     |                       | 
|All Directors and Officers as a group (6 persons) |  |                   | 9,779,603 |     |                       | 





|* |  | denotes ownership that does not exceed one percent.
|- |  | ---------------------------------------------------



|(1) | Unless otherwise indicated, address is 2492 Walnut Avenue, Suite 100, Tustin, California, 92780.
|--- | ------------------------------------------------------------------------------------------------



|(2) | In accordance with SEC rules, beneficial ownership includes sole or shared voting or investment power with respect to securities and includes the shares issuable pursuant to convertible securities that are exercisable within 60 days of the determination date, which in the case of the following table is June 15, 2012. Shares issuable pursuant to convertible securities are deemed outstanding for computing the percentage of the person holding such securities but are not outstanding for computing the percentage of any other person. Under these rules, one or more persons may be a deemed beneficial owner of the same securities and a person may be deemed a beneficial owner of securities to which such person has no economic interest. Unless otherwise indicated, the persons or entities identified in this table have sole voting and investment power with respect to all shares shown as beneficially owned by them, subject to applicable community property laws.
|--- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Page 122 of 132







|(3) | Includes, 8,000 shares of common stock issuable upon the exercise of options at $18.75 per share, 100,000 shares of common stock issuable upon the exercise of options at $9.75 per share, and 5,000,000 shares of common stock issuable upon the exercise of options at $0.11 per share.
|--- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



|(4) | Includes 2,000 shares of common stock issuable on exercise of options at $18.75 per share, 80,000 shares of common stock issuable upon the exercise of options at $9.75 per share, and 3,800,000 shares of common stock issuable upon the exercise of options at $0.11 per share.
|--- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



|(5) | Includes 8,000 shares of common stock issuable upon the exercise of options at $9.75 per share, 800,000 shares of common stock issuable upon the exercise of options at $0.11 per share, and 1,600 shares of common stock granted in August 2009.
|--- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



ITEM 13. CertainTransactions With
Related Persons, Promoters And Certain Control Persons



Other than the relationships and transactions
discussed below, we are not a party to, nor are we proposed to be a party, to any transaction during the last fiscal year involving
an amount exceeding $120,000 and in which a related person, as such term is defined by Item 404 of Regulation S-K, had or will
have a direct or indirect material interest.



During the year ended December 31, 2010,
Minghui Jia, a member of our board of directors, paid for certain JPI related expenses, totaling approximately $120,000, for which
we reimbursed him.



Review, Approval and Ratification of Related Party Transactions



In September 2008, our board approved the
Related Party Transaction Policy and Procedures. Pursuant thereto, it is our policy to discourage interested transactions with
related parties unless they are determined to be in our best interests and they have been approved in accordance with the terms
and conditions of the Policy. Accordingly, except as otherwise provided in the Policy, all Interested Transactions with Related
Parties (as those terms are defined in the Policy) require prior approval of (a) our Board of Directors, President and CEO (acting
in each case by a majority of the directors then in office who have no interest in a proposed Interested Transaction) or (b) the
Board of Directors (acting as above) and a committee of not less than two Independent Directors appointed by the Board of Directors
who have no interest in the proposed Interested Transaction being considered, in each case. Under the Policy, the Board of Directors
and either the President and CEO shall review the material facts of all Interested Transactions that require approval in accordance
with the Policy and either approve or disapprove of the entry into the Interested Transaction, subject to certain pre-approved
transactions (i.e. executive officer or director compensation specifically approved by our CEO and/or Compensation Committee, awards
granted pursuant to a shareholder approved stock option plan) that are included in the Policy. In determining whether to approve
an Interested Transaction, the Board of Directors, the President and CEO, as applicable, will take into account, among other factors
each deems appropriate, whether the Interested Transaction is on terms no less favorable than terms generally available to an unaffiliated
third-party under the same or similar circumstances and the extent of the Related Party’s interest in the transaction.



In connection with each regularly scheduled
meeting of the Board of Directors, a summary of each new Interested Transaction deemed pre-approved pursuant to the policy is provided
to the Board of Directors for its review. If an Interested Transaction will be ongoing, the Board of Directors may establish guidelines
for our management to follow in its ongoing dealings with the Related Party. Thereafter, the Board of Directors shall periodically
review and assess ongoing relationships with the Related Party to see that they are in compliance with such guidelines and that
the Interested Transaction remains appropriate.



Promoters and Certain Control Persons



None of our management or other control
persons were “promoters” (within the meaning of Rule 405 under the Securities Act), and none of such persons took the
initiative in the formation of our business or received any of our debt or equity securities or any of the proceeds from the sale
of such securities in exchange for the contribution of property or services, during the last five years.



Page 123 of 132







Director Independence



Under the Company’s
corporate governance principles (the “Corporate Governance Principles”), a majority of the Board will consist
of independent directors. Although we are no longer listed on the NYSE Amex, we still use their definition
of “independent” to determine if a director is independent, along with other applicable independence standards
under SEC guidelines, as determined by the Board. The Corporate Governance and Nominating Committee conducts an annual review
of the independence of the members of the Board and its Committees and reports its findings to the full Board. Based on
the report and recommendation of the Corporate Governance Committee, as of December 31, 2011 the Board has determined that
each of the non-employee directors — Dr. Beart, Dr. Rooks, Mr. Boswell, and Dr. Reyno —
satisfies the independence criteria (including the enhanced criteria with respect to members of the Audit Committee) set
forth  by the NYSE Amex and SEC rules. Each Board Committee consists entirely of independent, non-employee
directors.



For a director to be considered independent,
the Board must determine that the director does not have any direct or indirect material relationships (including vendor, supplier,
consulting, legal, banking, accounting, charitable and family relationships) with Radient, other than as a director and shareholder.



The Board considered all relevant facts
and circumstances in making its determinations, including the following:



| | · | No non-employee director receives any direct compensation from Radient other than under the director compensation program described in this proxy statement.
| | - | ------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | No immediate family member (within the meaning of the Amex listing standards) of any non-employee director is an employee of Radient or otherwise receives direct compensation from Radient.
| | - | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | No non-employee director (or any of their respective immediate family members) is affiliated with or employed in a professional capacity by Radient’s independent accountants.
| | - | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | No non-employee director is a member, partner, or principal of any law firm, accounting firm or investment banking firm that receives any consulting, advisory or other fees from Radient.
| | - | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | No Radient executive officer is on the compensation committee of the board of directors of a company that employs any of our non-employee directors (or any of their respective immediate family members) as an executive officer.
| | - | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | No non-employee director (or any of their respective immediate family members) is indebted to Radient, nor is Radient indebted to any non-employee director (or any of their respective immediate family members).
| | - | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | No non-employee director serves as an executive officer of a charitable or other tax-exempt organization that received contributions from Radient.
| | - | --------------------------------------------------------------------------------------------------------------------------------------------------







Due to our financial situation we are in arrears to Michael
Boswell for director fee and we are currently negotiating a potential advisory agreement with Mr. Boswell. As a result of the foregoing
the board has determined that Mr. Boswell is no longer an “independent” director.





Non-management members of the Board of
Directors conduct at least one regularly-scheduled meeting per year without members of management being present. Mr. Boswell
serves as the presiding director of such meetings. Following an executive session of non-employee directors, the presiding director
may act as a liaison between the non-employee directors and the Chairman, provide the Chairman with input regarding agenda items
for Board and Committee meetings, and coordinate with the Chairman regarding information to be provided to the non-employee directors
in performing their duties



Item 14. Principal Accountant Fees and Services



Aggregate fees for professional services rendered to the Company
by KMJ Corbin & Company LLP for the years ended December 31, 2011 and 2010 were as follows:



|Services Provided  |  | 2011 |         |  | 2010 |  
|------------------ |  | ---- | ------- |  | ---- | -
|Audit Fees         |  | $    | 417,000 |  |      | $
|Audit Related Fees |  |      | -       |  |      |  
|Tax Fees           |  |      | -       |  |      |  
|All Other Fees     |  |      | -       |  |      |  
|Total              |  | $    | 417,000 |  |      | $



Page 124 of 132







Audit Fees. The aggregate fees billed
for the years ended December 31, 2011 and 2010 were for the audits of our consolidated financial statements and reviews of our
interim consolidated financial statements included in our annual and quarterly reports.



Audit Related Fees. There were no
fees billed for the years ended December 31, 2011 and 2010 for the audit or review of our consolidated financial statements that
are not reported under Audit Fees.



Tax Fees. There were no fees billed
for the years ended December 31, 2011 and 2010 for professional services related to tax compliance, tax advice and tax planning.



All Other Fees. The aggregate fees
billed for the years ended December 31, 2011 and 2010 were for services other than the services described above.



Audit Committee Pre-Approval Policies and Procedures



The Audit Committee has implemented pre-approval
policies and procedures related to the provision of audit and non-audit services. Under these procedures, the Audit Committee pre-approves
both the type of services to be provided by KMJ Corbin & Company LLP and the estimated fees related to these services.



Page 125 of 132







PART IV

Item 15. Exhibits, Financial Statement Schedules



(a) Documents filed as part of this Annual Report on Form 10-K:

(1) The financial statements required to be included in this
Annual Report on Form 10-K are included in Item 8 of this Report.

(2) All other schedules have been omitted because they are not
required.(3) Exhibits:



|Exhibit Number |  | Description:                                                                                                                                                                                                                                    
|-------------- |  | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|3.1            |  | Certificate of Incorporation of Registrant. (Incorporated by reference to the Company’s Report on Form 10-KSB for the year ended December 31, 1989.)                                                                                            
|               |  |                                                                                                                                                                                                                                                 
|3.2            |  | Bylaws of the Company. (Incorporated by reference to the Company’s Report on Form 10-KSB for the year ended December 31, 1991.)                                                                                                                 
|3.3            |  | Certificate of Amendment of Certificate of Incorporation. (Incorporated by reference to the Company’s Report on Form 10-QSB for the period ended December 31, 1998.)                                                                            
|               |  |                                                                                                                                                                                                                                                 
|3.4            |  | Certificate of Amendment of Certificate of Incorporation filed with the Delaware Secretary of State on September 8, 2006. (Incorporated by reference to the Company’s definitive Proxy Statement dated July 14, 2006.)                          
|               |  |                                                                                                                                                                                                                                                 
|3.5            |  | Specimen of Common Stock Certificate. (Incorporated by reference to the Company’s Report on Form 10-KSB for the year ended December 31, 1999.)                                                                                                  
|               |  |                                                                                                                                                                                                                                                 
|3.6            |  | Certificate of Designations. (Incorporated by reference to the Company’s Report on Form 10-KSB for the year ended December 31, 1999.)                                                                                                           
|               |  |                                                                                                                                                                                                                                                 
|9.1            |  | Voting Trust Agreement by and between Jeanne Lai and Gary L. Dreher, as Co-Trustees, and Chinese Universal Technologies Co., Ltd. (Incorporated by reference to the Company’s Report on Form 8-K dated December 26, 2000.)                      
|               |  |                                                                                                                                                                                                                                                 
|10.1           |  | Amendments to License Agreement between the Company and Radient Canada, Inc., dated September 20, 1989, June 16, 1990 and July 5, 1990. (Incorporated by reference to the Company’s Report on Form 10-KSB for the year ended December 31, 1990.)
|               |  |                                                                                                                                                                                                                                                 
|10.2           |  | The Company’s 1992 Stock Option Plan. (Incorporated by reference to the Company’s Report on Form 10-KSB for the year ended December 31, 1991.)                                                                                                  
|               |  |                                                                                                                                                                                                                                                 
|10.3           |  | Operating Agreement of ICD, L.L.C. (Incorporated by reference to the Company’s Report on Form 10-KSB for the year ended December 31, 1993.)                                                                                                     
|               |  |                                                                                                                                                                                                                                                 
|10.4           |  | Letter Agreement between the Company and BrianaBio-Tech, Inc. and Radient Canada, Inc., dated February 7, 1995 (Incorporated by reference to the Company’s Report on Form 10-KSB for the year ended December 31, 1993.)                         
|               |  |                                                                                                                                                                                                                                                 
|10.5           |  | The Company’s Stock Bonus Plan (Incorporated by reference to the Company’s Report on Form 10-KSB for the year ended December 31, 1995.)                                                                                                         
|               |  |                                                                                                                                                                                                                                                 
|10.6           |  | Employment Agreement between the Company and Gary L. Dreher dated January 15, 1998 (Incorporated by reference to the Company’s Report on Form 10-KSB for the year ended December 31, 1997.)                                                     
|10.7           |  | Salary Continuation Agreement between the Company and That T. Ngo, Ph.D., dated May 21, 1998 (Incorporated by reference to the Company’s Report on Form 10-QSB for the period ended June 30, 1998.)                                             
|               |  |                                                                                                                                                                                                                                                 
|10.8           |  | Salary Continuation Agreement between the Company and Thomas V. Tilton dated May 21, 1998 (Incorporated by reference to the Company’s Report on Form 10-QSB for the period ended June 30, 1998.)                                                



Page 126 of 132







|10.9  |  | Salary Continuation Agreement between the Company and Harry Berk dated May 21, 1998 (Incorporated by reference to the Company’s Report on Form 10-QSB for the period ended June 30, 1998.)                                                                       
|----- |  | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|      |  |                                                                                                                                                                                                                                                                  
|10.10 |  | Salary Continuation Agreement between the Company and Gary L. Dreher dated May 21, 1998 (Incorporated by reference to the Company’s Report on Form 10-QSB for the period ended June 30, 1998.)                                                                   
|      |  |                                                                                                                                                                                                                                                                  
|10.11 |  | Agreement between the Company and William M. Thompson, M.D., dated May 21, 1998 (Incorporated by reference to the Company’s Report on Form 10-QSB for the period ended June 30, 1998.)                                                                           
|      |  |                                                                                                                                                                                                                                                                  
|10.12 |  | Amendment No. 1 to Employment Agreement with That T. Ngo, Ph.D., dated July 1, 1998 (Incorporated by reference to the Company’s Report on Form 10-QSB for the period ended June 30, 1998.)                                                                       
|      |  |                                                                                                                                                                                                                                                                  
|10.13 |  | Agreement Relating to Salary deferral between the Company and Thomas V. Tilton dated July 1, 1998 (Incorporated by reference to the Company’s Report on Form 10-QSB for the period ended June 30, 1998.)                                                         
|      |  |                                                                                                                                                                                                                                                                  
|10.14 |  | Agreement Relating to Salary deferral between the Company and Harry Berk dated July 1, 1998 (Incorporated by reference to the Company’s Report on Form 10-QSB for the period ended June 30, 1998.)                                                               
|      |  |                                                                                                                                                                                                                                                                  
|10.15 |  | Securities Purchase Agreement between the Company and the Purchasers listed on the Purchaser Signature Pages attached thereto, dated February 17, 1999. (Incorporated by reference to the Company’s Registration Statement on Form 10-SB dated October 15, 1999.)
|      |  |                                                                                                                                                                                                                                                                  
|10.16 |  | The Company’s 1999 Stock Option Plan (Incorporated by reference to the Company’s Registration Statement on Form 10-SB dated October 15, 1999.)                                                                                                                   
|      |  |                                                                                                                                                                                                                                                                  
|10.17 |  | Agreement Regarding Cancellation of Indebtedness between the Company and William M. Thompson, III, M.D., dated July 1, 1999 (Incorporated by reference to the Company’s Registration Statement on Form 10-SB dated October 15, 1999.)                            
|      |  |                                                                                                                                                                                                                                                                  
|10.18 |  | Agreement Regarding Cancellation of Indebtedness between the Company and Harry Berk dated July 1, 1999 (Incorporated by reference to the Company’s Registration Statement on Form 10-SB dated October 15, 1999.)                                                 
|      |  |                                                                                                                                                                                                                                                                  
|10.19 |  | Agreement Regarding Cancellation of Indebtedness between the Company and Edward Arquilla, M.D., dated July 1, 1999 (Incorporated by reference to the Company’s Registration Statement on Form 10-SB dated October 15, 1999.)                                     
|      |  |                                                                                                                                                                                                                                                                  
|10.20 |  | Agreement Regarding Cancellation of Indebtedness between the Company and Thomas V. Tilton dated July 1, 1999 (Incorporated by reference to the Company’s Registration Statement on Form 10-SB dated October 15, 1999.)                                           
|10.21 |  | Agreement Regarding Cancellation of Indebtedness between the Company and Donald Rounds, dated July 1, 1999 (Incorporated by reference to the Company’s Registration Statement on Form 10-SB dated October 15, 1999.)                                             
|10.22 |  | Agreement Regarding Cancellation of Indebtedness between the Company and That T. Ngo, Ph.D., dated July 1, 1999 (Incorporated by reference to the Company’s Registration Statement on Form 10-SB dated October 15, 1999.)                                        
|10.23 |  | Agreement Regarding Cancellation of Indebtedness between the Company and Gary L. Dreher dated July 1, 1999 (Incorporated by reference to the Company’s Registration Statement on Form 10-SB dated October 15, 1999.)                                             
|10.24 |  | Agreement Regarding Cancellation of Indebtedness between the Company and Douglas C. MacLellan dated July 1, 1999 (Incorporated by reference to the Company’s Registration Statement on Form 10-SB dated October 15, 1999.)                                       
|10.25 |  | Employment Agreement of Gary L. Dreher dated November 23, 1999 (Incorporated by reference to the Company’s Report on Form 10-KSB for the year ended December 31, 1999.)                                                                                          



Page 127 of 132







|10.26 |  | Consulting Agreement with That T. Ngo dated October 1, 1999 (Incorporated by reference to the Company’s Report on Form 10-KSB for the year ended December 31, 1999.)                                                                                                          
|----- |  | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|10.27 |  | Securities Purchase Agreement between the Company and the Purchasers listed on the Purchaser Signature Pages attached thereto dated February 9, 2000 (Incorporated by reference to the Company’s Report on Form 10-KSB for the year ended December 31, 1999.)                 
|10.28 |  | Securities Purchase Agreement dated as of December 14, 2000 executed December 19, 2000 (Incorporated by reference to the Company’s Report on Form 8-K dated December 26, 2000.)                                                                                               
|10.29 |  | Secured Promissory Note dated December 14, 2000, effective December 19, 2000 (Incorporated by reference to the Company’s Report on Form 8-K dated December 26, 2000.)                                                                                                         
|10.30 |  | Security and Pledge Agreement dated as of December 14, 2000, executed December 19, 2000 (Incorporated by reference to the Company’s Report on Form 8-K dated December 26, 2000.)                                                                                              
|10.31 |  | Voting Trust Agreement dated as of December 14, 2000, executed December 19, 2000. (Incorporated by reference to the Company’s Report on Form 8-K dated December 26, 2000.)                                                                                                    
|10.32 |  | Exclusive Distribution Agreement dated December 14, 2000, effective December 19, 2000. (Incorporated by reference to the Company’s Report on Form 8-K dated December 26, 2000.)                                                                                               
|10.33 |  | Technology Transfer Agreement effective July 30, 2001 between the Company and Lung-Ji Chang, Ph.D. (Incorporated by reference from the Company’s Report on Form 8-K dated August 31, 2001.)                                                                                   
|10.34 |  | Executive Management Change in Control Severance Plan. (Incorporated by reference from the Company’s Report on Form 10-KSB for the year ended December 31, 2001.)                                                                                                             
|10.35 |  | The Company’s 2002 Stock Option Plan. (Incorporated by reference from the Company’s Report on Form 10-KSB for the year ended December 31, 2002.)                                                                                                                              
|10.36 |  | The Company’s 2004 Stock Option Plan. (Incorporated by reference from the Company’s Report on Form 10-KSB for the year ended December 31, 2004.)                                                                                                                              
|10.37 |  | Employment Agreement of Gary L. Dreher dated January 31, 2005. (Incorporated by reference from the Company’s Form 8-K filed February 1, 2005.)                                                                                                                                
|10.38 |  | Letter of Intent with Jade Capital Group Ltd. dated November 21, 2005. (Incorporated by reference from the Company’s Form 8-K filed November 22, 2005.)                                                                                                                       
|10.39 |  | Stock Purchase and Sale Agreement between the Company and Jade Capital Group Limited dated May 12, 2006 and First Amendment to Purchase and Sale Agreement dated June 30, 2006. (Incorporated by reference from the Company’s definitive Proxy Statement dated July 14, 2006.)
|10.40 |  | 2006 Equity Incentive Plan. (Incorporated by reference from the Company’s definitive Proxy Statement dated July 14, 2006.)                                                                                                                                                    
|10.41 |  | Escrow Agreement between the Company and Jade Capital Group Limited (dated as of the closing on September 28, 2006. (Incorporated by reference from the Company’s definitive Proxy Statement dated July 14, 2006.)                                                            
|10.42 |  | Opinion of Amaroq Capital, LLC dated May 9, 2006. (Incorporated by reference from the Company’s definitive Proxy Statement dated July 14, 2006.)                                                                                                                              
|10.43 |  | Amendment No. 1 to Escrow Agreement dated August 10, 2007. (Incorporated by reference from the Company’s Form 10-K filed                                                                                                                                                      
|10.44 |  | Amendment No 2 to Escrow Agreement dated March 11, 2007                                                                                                                                                                                                                       
|10.45 |  | Employment Agreement of Gary L. Dreher dated March 31, 2008. (Previously filed)                                                                                                                                                                                               
|10.46 |  | Change in Control Severance Pay Plan. (Previously filed)                                                                                                                                                                                                                      
|10.47 |  | Product License, Distribution and Manufacturing Agreement with MGI dated March 28, 2008. (Incorporated by reference from the Company’s Form 8-K filed April 2, 2008.)                                                                                                         
|10.48 |  | 2008-2009 Performance Incentive Plan (Incorporated from the Company’s Form 8-K filed January 9, 2009)                                                                                                                                                                         
|10.49 |  | Amendment No. 3 to Escrow Agreement dated March 24, 2008                                                                                                                                                                                                                      
|10.50 |  | Note and Warrant Purchase Agreement dated March 22, 2010 (Incorporated by reference from the Form 8-K filed March 26, 2010.)                                                                                                                                                  
|10.51 |  | Form of Note (Incorporated by reference from the Form 8-K filed March 26, 2010.)                                                                                                                                                                                              
|10.52 |  | Form of Warrant (Incorporated by reference from the Form 8-K filed March 26, 2010.)                                                                                                                                                                                           
|10.53 |  | Form of Registration Rights Agreement dated March 22, 2010 (Incorporated by reference from the Form 8-K filed March 26, 2010.)                                                                                                                                                
|10.54 |  | Commercial Lease dated August 30, 2008 for the premises at 2492 Walnut Avenue, Suite 100, Tustin, California 92780 (Incorporated by reference from the Form 10-K/A filed May 3, 2010)                                                                                         
|10.55 |  | Collaboration Agreement with Mayo Validation Support Services dated December 12, 2008 (Incorporated by reference from the Form 10-K/A filed May 3, 2010)                                                                                                                      
|10.56 |  | Exclusive Distribution Agreement between the Company and Grifols USA, LLC dated September 20, 2009 (Incorporated by reference from the Form 10-K/A filed May 3, 2010)                                                                                                         



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|10.57 |  | Distribution Agreement between the Company and Tarom Applied Technologies dated September 30, 2009 (Incorporated by reference from the Form 10-K/A filed May 3, 2010)
|----- |  | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------
|10.58 |  | Form of Note and Warrant Purchase Agreement (Incorporated by reference from the Form 8-K filed April 13, 2010.)                                                      
|10.59 |  | Form of Note (Incorporated by reference from the Form 8-K filed April 13, 2010.)                                                                                     
|10.60 |  | Form of Warrant (Incorporated by reference from the Form 8-K filed April 13, 2010.)                                                                                  
|10.61 |  | Form of Addendum to Note and Warrant Purchase Agreement (Incorporated by reference from the Form 8-K filed April 13, 2010.)                                          
|10.62 |  | Form of Exchange Agreement (Incorporated by reference from the Form 8-K filed March 16, 2010.)                                                                       
|10.63 |  | Form of Waiver of Default dated February 16, 2010 (Incorporated by reference from the Form 8-K filed March 16, 2010.)                                                
|10.64 |  | Exclusive 5-Year Collaboration Agreement with Jaiva Technologies, Inc. dated April 1, 2010, (Incorporated by reference from the Form 10-K filed May 25, 2011).       
|      |  |                                                                                                                                                                      
|10.65 |  | Exclusive five-year distribution agreement with Jaiva Guar Diagno New Dehli. (Incorporated by reference from the Form 10-K filed May 25, 2011).                      
|      |  |                                                                                                                                                                      
|10.66 |  | Exclusive two-year distribution agreement with Naroo Ditech Inc. (Incorporated by reference from the Form 10-K filed May 25, 2011).                                  
|      |  |                                                                                                                                                                      
|10.67 |  | Form of Placement Agent Agreement with Jesup & Lamont dated November 30, 2009 (Incorporated by reference to the Form 8-K filed on December 2, 2009.)                 
|      |  |                                                                                                                                                                      
|10.68 |  | Form of Warrant (Incorporated by reference to the Form 8-K/A filed on October 8, 2010).                                                                              
|      |  |                                                                                                                                                                      
|10.69 |  | Form of Letter Agreement (Incorporated by reference to the Form 8-K filed on September 7, 2010.)                                                                     
|      |  |                                                                                                                                                                      
|10.70 |  | Form of Letter Agreement (Incorporated by reference to the Form 8-K filed on October 5, 2010.)                                                                       
|      |  |                                                                                                                                                                      
|10.71 |  | Form of Securities Purchase Agreement (incorporated by reference to Exhibit 10.1 to the 8-K filed on January 31, 2011.)                                              
|      |  |                                                                                                                                                                      
|10.72 |  | Form of Note (incorporated by reference to Exhibit 10.2 to the 8-K filed on January 31, 2011.)                                                                       
|      |  |                                                                                                                                                                      
|10.73 |  | Form of Warrant (incorporated by reference to Exhibit 10.3 to the 8-K filed on January 31, 2011.)                                                                    
|      |  |                                                                                                                                                                      
|10.74 |  | Registration Rights Agreement (incorporated by reference to Exhibit 10.4 to the 8-K filed on January 31, 2011.)                                                      
|      |  |                                                                                                                                                                      
|10.75 |  | Form of Exchange Agreement (incorporated by reference to Exhibit 10.1 to the 8-K filed on July 1, 2011.)                                                             
|      |  |                                                                                                                                                                      
|10.76 |  | Form of Notes (incorporated by reference to Exhibit 10.2 to the 8-K filed on July 1, 2011.)                                                                          
|      |  |                                                                                                                                                                      
|10.77 |  | Form of Warrant (incorporated by reference to Exhibit 10.3 to the 8-K filed on July 1, 2011.)                                                                        
|      |  |                                                                                                                                                                      
|10.78 |  | Exchange Agreement with the 2011 Note holders dated November 28, 2011 (incorporated by reference to Exhibit 10.1 to the 8-K filed on November 29, 2011.)             
|      |  |                                                                                                                                                                      
|10.79 |  | Form of Certificate of Designations of the Series B Convertible Preferred Stock (incorporated by reference to Exhibit 10.2 to the 8-K filed on November 29, 2011.)   
|10.80 |  | Form of Convertible Note (incorporated by reference to Exhibit 10.3 to the 8-K filed on November 29, 2011.)                                                          



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|10.81 |  | Form of Series A Warrant (incorporated by reference to Exhibit 10.4 to the 8-K filed on November 29, 2011.)                                                                                                                                                                                                                      
|----- |  | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.82 |  | Form of Series B Warrant (incorporated by reference to Exhibit 10.5 to the 8-K filed on November 29, 2011.)                                                                                                                                                                                                                      
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.83 |  | Form of Certificate of Designations of the Series C Convertible Preferred Stock (incorporated by reference to Exhibit 10.6 to the 8-K filed on November 29, 2011.)                                                                                                                                                               
|10.84 |  | Form of Convertible Debenture of JPI (incorporated by reference to Exhibit 10.1 to the 8-K filed on February 4, 2011.)                                                                                                                                                                                                           
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.85 |  | Form of Amended Convertible Debenture of JPI (incorporated by reference to Exhibit 10.83 to the S-1/A2 filed on February 14, 2012)                                                                                                                                                                                               
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.86 |  | Form of Consulting Agreement with Catawba Global, Ltd. (incorporated by reference to Exhibit 10.84 to the S-1/A2 filed on February 14, 2012)                                                                                                                                                                                     
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.87 |  | Form of Amendment with Catawba Global, Ltd. (incorporated by reference to Exhibit 10.85 to the S-1/A2 filed on February 14, 2012)                                                                                                                                                                                                
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.88 |  | Form of Consulting Agreement with First International Capital Group, Ltd. (incorporated by reference to Exhibit 10.86 to the S-1/A2 filed on February 14, 2012)                                                                                                                                                                  
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.89 |  | Form of Amendment with First International Capital Group, Ltd. (incorporated by reference to Exhibit 10.87 to the S-1/A2 filed on February 14, 2012)                                                                                                                                                                             
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.90 |  | Form of Consulting Agreement with Garden State Securities Inc. (incorporated by reference to Exhibit 10.88 to the S-1/A2 filed on February 14, 2012)                                                                                                                                                                             
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.91 |  | Form of Amendment with Garden State Securities Inc. (incorporated by reference to Exhibit 10.89 to the S-1/A2 filed on February 14, 2012)                                                                                                                                                                                        
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.92 |  | Form of Consulting Agreement with Galileo Asset Management SA (incorporated by reference to Exhibit 10.90 to the S-1/A2 filed on February 14, 2012)                                                                                                                                                                              
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.93 |  | Form of Amendment with Galileo Asset Management SA (incorporated by reference to Exhibit 10.91 to the S-1/A2 filed on February 14, 2012)                                                                                                                                                                                         
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.94 |  | Form of Consulting Agreement with Brighton Capital Ltd. (incorporated by reference to Exhibit 10.92 to the S-1/A2 filed on February 14, 2012)                                                                                                                                                                                    
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.95 |  | Form of Amendment with Brighton Capital Ltd. (incorporated by reference to Exhibit 10.93 to the S-1/A2 filed on February 14, 2012)                                                                                                                                                                                               
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.96 |  | Form of Consulting Agreement with JFS Investments (incorporated by reference to Exhibit 10.94 to the S-1/A2 filed on February 14, 2012)                                                                                                                                                                                          
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.97 |  | Form of Amendment with JFS Investments (incorporated by reference to Exhibit 10.95 to the S-1/A2 filed on February 14, 2012)                                                                                                                                                                                                     
|      |  |                                                                                                                                                                                                                                                                                                                                  
|10.98 |  | Form of Consulting Agreement with Cantone Asset Management, LLC (incorporated by reference to Exhibit 10.96 to the S-1/A2 filed on February 14, 2012)                                                                                                                                                                            
|10.99 |  | Agreement with the 2011 Note holders dated May 17, 2012 (incorporated by reference to Exhibit 10.1 to the 8-K filed on May 21, 2012.)                                                                                                                                                                                            
|21.1  |  | Subsidiaries of Radient Pharmaceuticals Corporation include Jade Pharmaceutical Inc., a British Virgin Islands corporation, Jiangxi Jiezhong Bio-Chemical Pharmacy Company Limited, a China WFOE, Yangbian Yiqiao Bio-Chemical Pharmacy Company Limited, a China WFOE, and Radient Diagnostics, Inc, a United States corporation.
|24.1  |  | Power of Attorney. (Included on signature page.)                                                                                                                                                                                                                                                                                 
|      |  |                                                                                                                                                                                                                                                                                                                                  



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|31.1 |  | Certification of Chief Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002. (Filed herewith.)                                         
|---- |  | --------------------------------------------------------------------------------------------------------------------------------------------------------------
|31.2 |  | Certification of Chief Financial Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002. (Filed herewith.)                                         
|32.1 |  | Certification of Chief Executive Officer pursuant to 18 U.S.C. § 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002. (Filed herewith.)
|32.2 |  | Certification of Chief Financial Officer pursuant to 18 U.S.C. § 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002. (Filed herewith.)



Page 131 of 132







SIGNATURES



Pursuant to the
requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the Registrant has duly caused this report to
be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Tustin, State of California on June 30, 2012.



|Radient Pharmaceuticals Corporation |                         
|----------------------------------- | ------------------------
|                                    |                         
|By:                                 | /s/ Douglas C. MacLellan
|Douglas C. MacLellan,               |                         
|Chief Executive Officer             |                         



POWER
OF ATTORNEY



ALL MEN BY THESE PRESENTS, that each person
whose signature appears below constitutes and appoints Douglas C. MacLellan and Akio Ariura, or either of them, as his true and
lawful attorneys-in-fact and agents, with full power of substitution and re-substitution, for him and in his name, place and stead,
in any and all capacities, to sign any and all amendments to this Annual Report on Form 10-K and any documents related to
this report and filed pursuant to the Securities Exchange Act of 1934, and to file the same, with all exhibits thereto, and other
documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents,
full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith
as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact
and agents, or their substitute or substitutes may lawfully do or cause to be done by virtue hereof.



Pursuant to the requirements of the Securities
Exchange Act of 1934, this report has been signed below by the following persons on behalf of the Registrant in the capacities
and on the dates indicated.



|Signature                |  | Title                                            |  | Date         
|------------------------ |  | ------------------------------------------------ |  | -------------
|                         |  |                                                  |  |              
|/s/ Douglas C. MacLellan |  | President, Chief Executive Officer, and Director |  | June 29, 2012
|DOUGLAS C. MACLELLAN     |  | (Principal Executive Officer)                    |  |              
|                         |  |                                                  |  |              
|/s/ Akio Ariura          |  | Chief Operating Officer, Chief Financial Officer |  | June 29, 2012
|AKIO ARIURA              |  | and Secretary (Principal Financial Officer and   |  |              
|                         |  | Principal Accounting Officer)                    |  |              
|                         |  |                                                  |  |              
|/s/ Michael Boswell      |  | Director                                         |  | June 29, 2012
|MICHAEL BOSWELL          |  |                                                  |  |              
|                         |  |                                                  |  |              



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