## Re: Laboratory method for NMP Christopher Lambesis to: Terri Zick 03/03/2010 10:08 AM Cc: Kathy Wilson, Todd Ramaly
From: Christopher Lambesis/R5/USEPA/US To: Terri Zick <tzick@cticompanies.com > Cc: Kathy Wilson <kathywilson@owossographic.com >, Todd Ramaly/R5/USEPA/US@EPA


### Terri, We agree to your proposed sampling and analysis methods for NMP as suggested below. I also suggest you separately send for analysis a sample of the raw NMP product (about 10m1 in a VOA vial). It is important that the laboratory is notified that this sample is pure product and should be diluted accordingly. Analysis of the diluted NMP product should help identify chromatographic retention time and possible breakdown constituents without derivatization. Christopher Lambesis Environmental Scientist U.S EPA Region 5 Land and Chemicals Division (312) 886-3583
We have confirmed with Trimatrix Laboratories .„ 03/02/20 0 12:35:17 PM

Terri Zick <tzk@cticompanies.com > Todd Ramaly/R5/USEPA/US@EPA, Christopher Lambesis/R5/USEPA/US@EPA Kathy Wilson <kathywilson@owossographic.com > 03/02/2010 12:35 PM Laboratory method for NMP 

### Terri Zick

From: To: Cc: Date: Subject:



### We have confirmed with Trimatrix Laboratories that Method 8270 will be the appropriate method under which to look for NMP as a TIC (Please see the pertinent excerpt from their e-mail response below)
We propose collecting 3 composite samples from the roll-off box which is currently full & scheduled for shipment on March 11, 2010. The filter cake in the box represents 6 press cleanings within the past 75 days. We propose collecting a series of 3 samples, each composited from 2 locations within the container. Two samples would be collected from the north third, 2 from the central portion of the box and 2 from the south end of the box. Each set of 2 samples would be composited to constitute a single sample and analyzed using method 8270 without a method 1311 extraction. The chromatograms from the analysis will be used to identify NMP, if present, as a TIC. While TIC's are, by definition, not validated results in the same way that a sample is validated against a standard, the method blank, surrogate and internal standard recovery, and the DFTPP tune summary will 

### demonstrate that the sample was run on an analytical system that was in control and valid for the method by which the sample was analyzed. If the laboratory detects hits of this compound in these samples, the raw data will include the library search report along with the supporting data we used to make the tentative identification so a 3 rd party reviewer could confirm those results using information from the data package.
Based on production, Owosso Graphic Arts is shipping every 90 or fewer days so the window of opportunity for sample collection is small. We would like to come to concurrence on the number of

### samples that you would deem acceptable and confirmation that you find the analytical approach using

method 8270 appropriate for your purposes.
Thank you in advance for your review & response.

Terri Zick 313-300-7401



### Hi Terri, I had our Lab Manager review this. Method 8270 would be our best bet. We have no standard for it, so it would have to be done as a TIC.

Gary Wood Senior Project Chemist

Corporate / Laboratory 5560 Corporate Exchange Court SE Grand Rapids, Michigan 49512 woodgl@trimatrixlabs.com Main: 616.975.4500 Direct: 616.940.4206 Fax: 616.942.7463 www.trimatrixlabs.com

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