Re: Laboratory method for NMP 

Christopher Lambesis to: Terri Zick 03/03/2010 10:08 AM 

Cc: Kathy Wilson, Todd Ramaly 

From: Christopher Lambesis/R5/USEPA/US 

To: Terri Zick <tzick@cticompanies.com> 

Cc: Kathy Wilson <kathywilson@owossographic.com>, Todd Ramaly/R5/USEPA/US@EPA 

Terri, 

We agree to your proposed sampling and analysis methods for NMP as suggested below. I also suggest 

you separately send for analysis a sample of the raw NMP product (about 10m1 in a VOA vial). It is 

important that the laboratory is notified that this sample is pure product and should be diluted accordingly. 

Analysis of the diluted NMP product should help identify chromatographic retention time and possible 

breakdown constituents without derivatization. 

Christopher Lambesis 

Environmental Scientist 

U.S EPA Region 5 

Land and Chemicals Division 

(312) 886-3583 

We have confirmed with Trimatrix Laboratories .„ 03/02/20 0 12:35:17 PM 

Terri Zick <tzk@cticompanies.com> 

Todd Ramaly/R5/USEPA/US@EPA, Christopher Lambesis/R5/USEPA/US@EPA 

Kathy Wilson <kathywilson@owossographic.com> 

03/02/2010 12:35 PM 

Laboratory method for NMP 

Terri Zick 

From: 

To: 

Cc: 

Date: 

Subject: 

We have confirmed with Trimatrix Laboratories that Method 8270 will be the appropriate method 

under which to look for NMP as a TIC (Please see the pertinent excerpt from their e-mail response 

below) 

We propose collecting 3 composite samples from the roll-off box which is currently full & scheduled for 

shipment on March 11, 2010. The filter cake in the box represents 6 press cleanings within the past 75 

days. We propose collecting a series of 3 samples, each composited from 2 locations within the 

container. Two samples would be collected from the north third, 2 from the central portion of the box 

and 2 from the south end of the box. Each set of 2 samples would be composited to constitute a single 

sample and analyzed using method 8270 without a method 1311 extraction. The chromatograms from 

the analysis will be used to identify NMP, if present, as a TIC. 

While TIC's are, by definition, not validated results in the same way that a sample is validated against a 

standard, the method blank, surrogate and internal standard recovery, and the DFTPP tune summary will 

demonstrate that the sample was run on an analytical system that was in control and valid for the method 

by which the sample was analyzed. If the laboratory detects hits of this compound in these samples, the 

raw data will include the library search report along with the supporting data we used to make the tentative 

identification so a 3rdparty reviewer could confirm those results using information from the data package. 

Based on production, Owosso Graphic Arts is shipping every 90 or fewer days so the window of 

opportunity for sample collection is small. We would like to come to concurrence on the number of 
samples that you would deem acceptable and confirmation that you find the analytical approach using 

method 8270 appropriate for your purposes. 

Thank you in advance for your review & response. 

Terri Zick 

313-300-7401 

Hi Terri, 

I had our Lab Manager review this. Method 8270 would be our best bet. We have no standard for it, so it 

would have to be done as a TIC. 

Gary Wood 

Senior Project Chemist 

Corporate / Laboratory 

5560 Corporate Exchange Court SE 

Grand Rapids, Michigan 49512 

woodgl@trimatrixlabs.com 

Main: 616.975.4500 

Direct: 616.940.4206 

Fax: 616.942.7463 

www.trimatrixlabs.com 

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