Employment Agreement between Patheon and Paul M. Garofolo dated May 12, 2008




 Exhibit 10.33 
 [PATHEON] 
 Date: January 15, 2009 

PRIVATE AND CONFIDENTIAL 
 Paul M.
Garofolo 
 1436 Mariners Drive 

Newport Beach, California 92660 
 Dear Paul:

 RE: Employment Agreement: 
 I am pleased to confirm the terms of your employment (“Employment Agreement”), dated May 12, 2008. This Employment Agreement represents your contractual arrangements with Patheon
Pharmaceutical Services Inc. (the “Corporation”) and supersedes any arrangements, understandings and verbal commitments to you during our discussions. 
  

	
	Sincerely,
	
	/s/ Wesley P. Wheeler
	
	Wesley P. Wheeler
	Chief Executive Officer









 EMPLOYMENT AGREEMENT 

THIS AGREEMENT is made as of the 12th day of May, 2008 between Patheon Pharmaceutical Services Inc. (the
“Corporation”) and Paul M. Garofolo, an Executive residing in the City of Newport Beach, in the State of California (the “Executive”). 
 WHEREAS, the Corporation and the Executive wish to enter into this Agreement to set forth the rights and obligations of each of them with respect to the employment of the Executive. 

WHEREAS, the Corporation agrees to employ the Executive on the terms and subject to the conditions set forth in this Agreement to render
exclusive and full-time services to the Affiliated Group (as defined below). 
 NOW, THEREFORE, THIS AGREEMENT WITNESSES that in
consideration of the premises and mutual covenants and agreements hereinafter contained and other good and valuable consideration (the receipt and sufficiency of which is hereby acknowledged), the parties agree with each other as follows:

 ARTICLE 1 
 INTERPRETATION 
  

	1.1	Governing Law. This Agreement shall be construed and interpreted in accordance with the laws of the State of New York. Each of the parties hereby
irrevocably consents to the jurisdiction of the courts in the State of New York with respect to any matters arising out of this Agreement. 

  

	1.2	Definitions. In this Agreement, including Schedule A and B hereto, unless, the context otherwise requires, the following terms shall have the following
meanings, respectively: 

  

	 	(a)	“Affiliated Group” means the Corporation and any entity controlled by, controlling, or under common control with the Corporation.


  

	 	(b)	“Agreement” means this Employment Agreement as it may be amended or supplemented from time to time. 


 

	 	(c)	“Annual Base Salary” has the meaning given such term in Section 3.1. 


 

	 	(d)	“Board of Directors” means the Board of Directors of Patheon. 


 

	 	(e)	 “Cause” means the determination, in good faith, by the Board of Directors, after notice to the Executive and, if curable, a reasonable
opportunity to cure, that one or more of the following events has occurred: (i) the Executive has failed to perform his material duties, and such failure has not been cured after a period of












	 	 
30 days notice from the Corporation; (ii) any reckless or grossly negligent act by the Executive having the effect of injuring the interests, business or reputation of any member of the
Affiliated Group in any material respect; (iii) the Executive’s commission of any felony (including entry of a nolo contendere plea); (iv) any misappropriation or embezzlement of the property of any member of the
Affiliated Group; or (v) a breach of any material provision of this Agreement by the Executive. 


  

	 	(f)	“Change in Control” means any of the following events: 

  

	 	(i)	Any “Person” (within the meaning of Section 13(d)(3) or 14(d)(2) of the Securities Exchange Act of 1934, as amended (the “Exchange
Act”)), other than JLL Partners or its affiliates, becomes a Beneficial Owner (within the meaning of Exchange Act Rule 13d-3) of more than fifty percent (50%) of the voting power of the then outstanding voting securities of Patheon
entitled to vote generally in the election of directors; 

  

	 	(ii)	There is consummated a merger or consolidation of Patheon or any direct or indirect subsidiary of Patheon with any other company, other than a merger or consolidation
that would result in the voting securities of Patheon outstanding immediately prior to such merger or consolidation continuing to represent (either by remaining outstanding or by being converted into voting securities of the surviving entity or any
parent thereof) at least fifty percent (50%) of the combined voting power of the securities of Patheon or such surviving entity or any parent thereof outstanding immediately after such merger or consolidation; or 


 

	 	(iii)	The stockholders of Patheon approve a plan of complete liquidation or dissolution of the company or there is consummated an agreement for the sale or disposition by
Patheon of all or substantially all of its assets. 

  

	 	(g)	“Code” means the Internal Revenue Code of 1986, as amended. 


 

	 	(h)	“Competitor” has the meaning given such term in Section 6.4. 


 

	 	(i)	“Date of Termination” has the meaning given such term in Section 4.5. 


 

	 	(j)	“Effective Date” has the meaning given such term in Section 2.1. 


 

	 	(k)	 “Good Reason” means the occurrence of any of the following events without the consent of the Executive: (i) a material reduction
by the Corporation of the Executive’s duties or responsibilities or the assignment to the Executive of duties or responsibilities materially inconsistent with the Executive’s position; or (ii) a material breach by the Corporation of
this Agreement. A termination of the Executive’s employment by Executive shall not be deemed to be for Good Reason unless (i) the Executive gives notice to the Corporation of the existence of the event or condition constituting Good Reason
within 30 days after such event or condition initially occurs or exists, (ii) the Corporation fails to cure such event or condition within 30 days after receiving such notice, and (iii) the












	 	 
Executive’s “separation from service” within the meaning of Section 409A of the Code occurs not later than 90 days after such event or condition initially occurs or
exists.1 



 

	 	(l)	“Patheon” means Patheon Inc. 

  

	 	(m)	“Target Bonus” has the meaning given such term in Section 3.2. 


ARTICLE 2 

EFFECTIVE DATE; TERMS OF EMPLOYMENT 
  

	2.1	Term 

 The
Corporation hereby agrees to employ the Executive, and the Executive hereby agrees to be employed by the Corporation on the terms and subject to the conditions of this Agreement (including, without limitation, Article 6), commencing on May 12,
2008, (the “Effective Date”). 
  

	2.2	Position and Duties 


The Executive shall serve as the Chief Information Officer of Patheon, with such authority, duties and responsibilities as are
commensurate with such position, reporting to the Chief Technical Officer for all global IT matters and to the Chief Executive Officer for operational excellence and other matters. In addition, the Executive will be a member of the Patheon Technical
Management Committee. 
 The Executive shall also be responsible for the functions and responsibilities set out in the Position
Description for the Chief Information Officer, attached as Schedule A. 
  

	2.3	Time Commitments 


During the Executive’s employment, the Executive shall devote substantially all of his business time energies and talents to serving
as the Chief Information Officer of Patheon, perform his duties conscientiously and faithfully subject to the reasonable and lawful directions of the Chief Technical Officer or the Chief Executive Officer, as appropriate, and in accordance with each
of the corporate governance and ethics guidelines, conflict of interests policies and code of conduct applicable to all employees or senior executives generally of the Affiliated Group. During the Executive’s employment, it shall not be a
violation of this Agreement for the Executive, subject to the requirements of Article 6, to (a) serve on corporate, civic or charitable boards or committees, (b) deliver lectures or fulfill speaking engagements and (c) manage personal
investments, so long as such activities do not materially interfere with the performance of the Executive’s duties or responsibilities under this Agreement. 

 

	1	 In order to comply with Section 409A, this definition is slightly different from the definition in the term sheet. 











	2.4	Location 

  

	 	(a)	Initially, it is understood that the Executive’s principal office will be a home office located in the Executive’s residence in the city of Newport Beach,
California. 

  

	 	(b)	While the Executive’s principal office is located in the Executive’s residence, the Corporation shall reimburse the Executive for reasonable automobile
expenses and travel expenses associated with him commuting from his personal residence in California to Patheon’s current corporate headquarters during this period. The Corporation shall also reimburse the Executive for reasonable expenses
incurred to set up a home office, including to obtain necessary office equipment, supplies and set-up services, in accordance with the Corporation’s policy and procurement practices. Reimbursements under this Section 2.4(b) shall be paid
to the Executive in the calendar month after the month in which they are incurred, subject to such reasonable documentation requirements as may be requested from time to time by the Corporation. 


 

	 	(c)	When the new U.S. headquarters location in North Carolina is available for occupancy, the Corporation will require the Executive to be based within this facility. Under
the terms of Patheon’s Tier 1 relocation program, the Executive shall be reimbursed for all reasonable transaction costs and expenses (including any real estate brokerage fees, commissions and closing costs, but excluding any loss on the sale
of the Executive’s personal residence) and moving expenses incurred by the Executive, in connection with relocating the Executive’s spouse, dependents and personal property and goods from the Executive’s current residence.
Reimbursements under this Section 2.4(c) shall be paid to the Executive in the calendar month after the month that they are incurred, subject to such reasonable documentation requirements as may be requested from time to time by the
Corporation. 

 ARTICLE 3 
 COMPENSATION AND BENEFITS 
  

	3.1	Base Salary 

 The
Corporation shall pay the Executive an annualized base salary (“Annual Base Salary”) at a rate of not less than $290,000 US, payable in regular installments in accordance with the Corporation’s normal payroll practices. The Annual
Base Salary shall be reviewed by the Chief Executive Officer, for increase only, at such time as the salaries of other senior executives of Patheon are reviewed generally. If so increased, the Annual Base Salary shall be increased for all purposes
of this Agreement. 
  

	3.2	Executive Performance Bonus  

 For each fiscal year, the Executive shall be eligible to participate in an annual incentive plan under terms and conditions no less favorable than other senior executives of Patheon; provided that the
Executive’s Target Bonus shall not be less than 40% of his Annual Base Salary. The Executive’s payment under the annual incentive plan shall be based on meeting predetermined personal objectives and Patheon’s financial performance.
Both the personal objectives and financial performance measures will be 








 
recommended by the Executive and subject to final approval by the Chief Executive Officer. For fiscal 2008, the performance bonus will be prorated from the Effective Date. The annual performance
bonus, if earned, will be paid to the Executive by the Corporation in the same manner and payment period generally applicable under the annual incentive plan, but in no event later than two and a half months after the later of (i) the end of
the applicable performance period, or (ii) the end of the calendar year in which the performance period ends. Nothing contained in this Section 3.2 will guarantee the Executive any specific amount of incentive compensation, or prevent the
Chief Executive Officer from establishing performance goals and compensation targets applicable only to the Executive. 
  

	3.3	Sign-on Bonus 

 The
Corporation will pay the Executive in a lump sum, within 30 business days of the Effective Date, a sign-on bonus of $50,000 US. If Executive voluntarily terminates employment with the Corporation other than for Good Reason within one year after the
Effective Date, Executive shall reimburse the Corporation this $50,000 payment within 30 days of termination. If Executive fails to make this reimbursement payment within 30 days of termination, the Corporation shall withhold the unpaid amount from
any amounts otherwise owed to the Executive (but only to the extent those amounts are not considered deferred compensation under Section 409A). 
  

	3.4	Equity Compensation  

  

	 	(a)	Subject to the approval of the Board of Directors, the Executive shall be granted a stock option to purchase 75,000 shares of common stock of Patheon at an exercise
price per share equal to the market value of the common stock on the date of the grant (the “Option”). Except as otherwise provided in the Amended and Restated Incentive Stock Option Plan (the “ISOP”) or stock option award
agreement (together with the ISOP, the “Stock Related Documents”), the Option will (i) vest as to 1/3 of the shares subject to the Option on each of the first three anniversaries of the date of grant, subject to the Executive’s
continued employment with the Affiliated Group until the relevant vesting dates, and (ii) have a seven year term. The Option will be subject to the terms, definitions and provisions of the applicable Stock Related Documents.


  

	 	(b)	During the Executive’s employment, at the discretion of the Board of Directors or its delegate, the Executive also shall be eligible to receive additional stock
options and other long-term incentives under the ISOP or any similar plan adopted by Patheon from time to time. 

  

	 	(c)	Upon the occurrence of a Change in Control, any stock options to purchase shares of the common stock of Patheon then held by the Executive shall, to the extent not
otherwise provided in the applicable Stock Related Documents, become immediately vested and exercisable and shall remain exercisable for the remaining term of such stock option (which remaining term shall be determined without regard to the
Executive’s termination of employment). 










	 	(d)	The Executive will be required to comply with the terms of any share ownership guidelines applicable to senior executives of Patheon generally, as amended from time to
time. 

  

	3.5	Retirement Benefits  

 Executive will be entitled to participate in the 401(k) retirement plan and any other qualified or nonqualified deferred compensation and retirement plans maintained by the Corporation applicable to
senior executives of the Corporation generally, in each case as amended from time to time. 
  

	3.6	Other Benefit Plans  

 During the Executive’s employment, the Executive also shall be entitled to participate in all welfare, perquisites, fringe benefit, and other benefit plans, practices, policies and programs, as may
be in effect from time to time, for U.S. resident-based senior executives of Patheon generally. 
 The Corporation shall also pay
the Executive, in regular semi-monthly installments, an allowance of $1,200 US per month for car related expenses. 
 In
addition, beginning with calendar year 2009, the Corporation shall pay for an annual club membership of the Executive’s choice up to $2,000 US per annum. This club membership payment shall be made in cash to the Executive in January of each
year once documentation of the expenditure or invoice has been provided to Patheon. 
  

	3.7	Expenses 

 The
Executive shall be reimbursed for all reasonable travel and other out-of-pocket expenses actually and properly incurred by the Executive during the Executive’s employment in connection with carrying out his duties hereunder in accordance with
the Corporation’s policies, as may be in effect from time to time, for its senior executives generally. 
  

	3.8	Vacation  

 During
the Executive’s employment, the Executive shall be entitled to four (4) weeks paid vacation in addition to four (4) floating holidays annually in accordance with the Corporation’s policies, as may be in effect from time to time,
for its senior executives generally. 
 ARTICLE 4 
 TERMINATION OF EMPLOYMENT 
  

	4.1	Death or Disability 


The Executive’s employment shall terminate automatically upon the Executive’s death. If the Corporation determines in good faith
that the Disability (as defined below) of the 








 
Executive has occurred during the Executive’s employment, it may give to the Executive written notice in accordance with Section 7.4 of this Agreement of its intention to terminate the
Executive’s employment; provided that such notice is provided no later than 150 days following the Executive’s first day of Disability. In such event, the Executive’s employment shall terminate effective on the 30th day after receipt
of such notice by the Executive (the “Disability Effective Date”), provided that, within the 30 days after such receipt, the Executive shall not have returned to full-time performance of the Executive’s duties. For purposes of this
Agreement, “Disability” shall mean the failure of the Executive to perform his duties under this Agreement for at least 90 consecutive business days as a result of any medically determinable physical or mental impairment. The determination
of Disability shall be made by a physician selected by the Corporation or its insurers and reasonably acceptable to the Executive or the Executive’s legal representative. 

 

	4.2	Cause 

 The
Executive’s employment with the Corporation may be terminated with or without Cause. 
  

	4.3	Good Reason 

 The
Executive’s employment with the Corporation may be terminated by the Executive with or without Good Reason. 
  

	4.4	Notice of Termination 

 Any termination by the Corporation for Cause, or by the Executive for Good Reason, shall be communicated by Notice of Termination to the other party in accordance with Section 7.4. For purposes of
this Agreement, a “Notice of Termination” means a written notice which (a) indicates the specific termination provision in this Agreement relied upon, (b) to the extent applicable, sets forth in reasonable detail the facts and
circumstances claimed to provide a basis for termination of the Executive’s employment under the provision so indicated and (c) if the Date of Termination (as defined below) is other than the date of receipt of such notice, specifies the
termination date (which date shall be not more than 30 days after the giving of such notice). The failure by the Corporation or the Executive to set forth in the Notice of Termination any fact or circumstance which contributes to a showing of Cause
or Good Reason shall not waive any right of the Corporation or the Executive, respectively, hereunder or preclude the Corporation or the Executive, respectively, from asserting such fact or circumstance in enforcing the Corporation’s or the
Executive’s rights hereunder. 
  

	4.5	Date of Termination  

 “Date of Termination” means (a) if the Executive’s employment is terminated by the Corporation for Cause, or by the Executive for Good Reason, the date of receipt of the Notice of
Termination or any later date specified therein, as the case may be (b) if the Executive’s employment is terminated by the Corporation other than for Cause or Disability, the Date of Termination shall be the date on which the Corporation
notifies the Executive of such termination and (c) if the Executive’s employment is terminated by 








 
reason of death or Disability, the Date of Termination shall be the date of death of the Executive or the Disability Effective Date, as the case may be. The Corporation and the Executive shall
take all steps necessary (including with regard to any post-termination services by the Executive) to ensure that any termination described in this Section 4.5 constitutes a “separation from service within the meaning of Section 409A
of the Code, and the date on which such separation from service takes place shall be the “Date of Termination.” 
  

	4.6	Resignation from All Positions  

 Notwithstanding any other provision of this Agreement, upon the termination of the Executive’s employment for any reason, unless otherwise requested by the Board of Directors, the Executive shall
immediately resign as of the Date of Termination from all positions that he holds or has ever held with the Affiliated Group (and with any other entities with respect to which the Affiliated Group has requested the Executive to perform services),
The Executive hereby agrees to execute any and all documentation to effectuate such resignations upon request by the Corporation, but he shall be treated for all purposes as having so resigned upon termination of his employment, regardless of when
or whether he executes any such documentation. 
 ARTICLE 5 

OBLIGATIONS OF CORPORATION UPON TERMINATION 
  


	5.1	Good Reason; Other than for Cause 

 If the Corporation shall terminate the Executive’s employment other than for Cause, or if the Executive shall terminate the Executive’s employment for Good Reason: 

 

	 	(a)	The Corporation shall pay, or cause to be paid, to the Executive in a lump sum in cash the sum of: (i) the Executive’s Annual Base Salary through the Date of
Termination, and (ii) any accrued vacation pay, in each case to the extent not theretofore paid (the sum of the amounts described in clauses (i) and (ii) shall be hereinafter referred to as the “Accrued Obligations”). The
Accrued Obligations shall be paid within 30 days after the Date of Termination. 

  

	 	(b)	The Corporation shall pay, or cause to be paid, to the Executive in a lump sum in cash an amount equal to the Executive’s Annual Base Salary. Such lump sum payment
shall be made within 60 days after the Date of Termination or such later date set forth in Section 7.8. 

  

	 	(c)	To the extent not theretofore paid or provided, the Affiliated Group shall pay or provide, or cause to be paid or provided, to the Executive any other amounts or
benefits required to be paid or provided or which the Executive is eligible to receive under any plan, program, policy or practice or contract or agreement of the Affiliated Group (such other amounts and benefits shall be hereinafter referred to as
the “Other Benefits”), in accordance with the terms and normal procedures of each such plan, program, policy or practice or contract or agreement, based on accrued and vested benefits through the Date of Termination.











	 	(d)	The Corporation shall pay, or cause to be paid, to the Executive in a lump sum in cash an amount equal to the Executive’s “average annual bonus”
(described below). Such payment shall be made within 60 days after the Date of Termination, or such later date set forth in Section 7.8, and shall be in lieu of any annual incentive for the year of termination. For this purpose, average annual
bonus means an amount equal to the average of the bonuses earned by the Executive under the Corporation’s annual incentive plan for the last two fiscal years prior to the Date of Termination. For purposes of clarity, (i) if the Executive
earns a prorated bonus for one or more of the applicable years, the average annual bonus will be calculated using the prorated amount for such year(s), and (ii) if the Executive does not receive a bonus for one or more of the applicable years,
the average annual bonus will be calculated using a zero dollar amount for such year(s). 

  

	 	(e)	If the Date of Termination occurs within twelve months after the occurrence of a Change in Control, then, in lieu of the amounts described in Sections 5.1(b) and
(d) above, the Corporation shall pay, or cause to be paid, to the Executive in a lump sum in cash the sum of: (i) the Executive’s Annual Base Salary and (ii) the Executive’s Target Bonus. Such lump sum payment shall be made
within 60 days after the Date of Termination or such later date set forth in Section 7.8. 

 If the Executive
receives payments and benefits pursuant to this Section 5.1, then the Executive shall not be entitled to any other severance pay or benefits under any severance plan, program or policy of any member of the Affiliated Group, unless otherwise
specifically provided therein in a specific reference to this Agreement. 
  

	5.2	Death or Disability; Cause; Other than for Good Reason  

 If the Executive’s employment is terminated due to death or Disability or for Cause, or if the Executive voluntarily terminates his employment without Good Reason, this Agreement shall terminate
without further obligations to the Executive other than the obligation to pay to the Executive his Accrued Obligations through the Date of Termination and the Other Benefits, in each case to the extent not theretofore paid or provided. Subject to
any withholding required by Section 3.3, all Accrued Obligations shall be paid to the Executive in accordance with Section 5.1(a) and the Other benefits shall be paid to the Executive in accordance with Section 5.1(c). 

 

	5.3	Release 


Notwithstanding anything contained herein to the contrary, the Corporation shall only be obligated to make the payments under Sections
5.1(b), 5.1(d) and 5.1(e) if: (a) within the 50-day period after the Date of Termination, the Executive executes a general release, in a form provided by the Corporation, of all current or future claims, known or unknown, against the Affiliated
Group, its officers, directors, shareholders, employees and agents arising on or before the date of the release, including but not limited to all claims arising out of the Executive’s employment with the Affiliated Group or the termination of
such employment, and (b) the Executive does not revoke the release during the seven-day revocation period prescribed by the Age Discrimination in 








 
Employment Act of 1967, as amended, or any similar revocation period, if applicable. The Corporation shall be obligated to provide such release to the Executive promptly following the Date of
Termination. 
 ARTICLE 6 
 RESTRICTIVE COVENANTS 
  

	6.1	In General  

 The
Executive acknowledges that in the course of his employment he will become familiar with trade secrets and customer lists of and other confidential information concerning the Affiliated Group and that his services have been of special, unique and
extraordinary value to the Affiliated Group. 
  

	6.2	Confidentiality Undertaking 

 The Executive confirms that he is bound by the provisions of the Confidentiality Undertaking covenant set out in Schedule B hereto. 

 

	6.3	Non-Solicitation 

  

	 	(a)	During the 12-month period immediately following the Date of Termination, the Executive shall not in any manner, directly or indirectly, solicit, induce or attempt to
solicit or induce any employee of any member of the Affiliated Group to quit or abandon his or her employ or to become an officer, agent, employee, partner, director, consultant or independent contractor of the Executive, his affiliates or any other
individual or entity. 

  

	 	(b)	During the 12-month period immediately following the Date of Termination, the Executive shall not in, any manner, directly or indirectly, solicit, induce or attempt to
solicit or induce, any customer, supplier or licensor of any member of the Affiliated Group to cease doing business with any member of the Affiliated Group, or in any way interfere with the relationships between any customer, supplier or licensor of
the Affiliated Group. 

  

	6.4	Non-Competition  


During the 12-month period immediately following the Date of Termination, the Executive shall not in any manner, directly or indirectly,
compete with the business of any member of the Affiliated Group by (a) becoming an officer, agent, employee, partner, director, consultant, independent contractor of a Competitor, or (b) acquiring an ownership interest in a Competitor,
provided that the Executive may, for investment purposes, own not more than 1% of the outstanding stock of any class of a Competitor that is listed on a recognized stock exchange or traded in the over-the-counter market in Canada or the United
States. For purposes of this Agreement, the term “Competitor” means any person or entity that engages in the pharmaceutical development and manufacturing outsourcing business in Canada, the United States (including the Commonwealth of
Puerto Rico), India or Europe. Notwithstanding the foregoing, this Section 6.4 shall not apply if, the Executive is terminated by the Corporation other than for Cause. 









	6.5	Reasonableness and Revision 

 The Executive agrees and acknowledges that due to the uniqueness of his services and the confidential nature of the information he will possess, the covenants set forth in this Article 6 and Schedule B
are reasonable and necessary for the protection of the business interests and goodwill of the Affiliated Group. Moreover, the geographic restriction on competitive activities by the Executive is reasonable, given the global nature of the Affiliated
Group’s business and the Executive’s role in that business. If, at the time of enforcement of this Article and/or Schedule B, a court or other tribunal holds that the restrictions herein are in whole or in part unreasonable under
circumstances then existing, the parties agree that the maximum period or scope reasonable under such circumstances will be substituted for the stated period or scope and that the court or other tribunal shall be authorized and directed by the
parties to revise the restrictions contained herein to cover the maximum period or scope permitted by law. 
  

	6.6	Acknowledgements  


The Executive agrees and acknowledges that the promises and obligations made by the Corporation in this Agreement (specifically including,
but not limited to, the payments and benefits provided for under Section 5.1(b) and (d) hereof) constitute sufficient consideration for the covenants contained in this Article 6. The Executive further acknowledges that it is not the
Affiliated Group’s intention to interfere in any way with his employment opportunities, except in such situations where the same conflict with the legitimate business interests of the Affiliated Group. The Executive agrees that he will notify
the Corporation in writing if he has, or reasonably should have, any questions regarding the applicability of this Article 6. 
  

	6.7	Enforcement 


Because the Executive’s services are unique and because the Executive has access to Confidential Information and work product, the
parties agree that the Affiliated Group will be damaged irreparably in the event any of the provisions of Section 6.2, 6.3 and 6.4 are not performed in accordance with their specific terms or are otherwise breached and that money damages will
be an inadequate remedy for any such non-performance or breach. Therefore, any one or more of the members of the Affiliated Group, or their respective successors and assigns, will be entitled, in addition to other rights and remedies existing in
their favor, to an injunction or injunctions to prevent any breach or threatened breach of any of such provisions and to enforce such provisions specifically (without posting a bond or other security). The Executive agrees and acknowledges that he
will not assert in any such enforcement action that there is an adequate remedy in damages and that such rights and remedies will be in addition to and not in lieu of any other rights or remedies available to the Affiliated Group at law or in
equity. 
  

	6.8	Survival 

 Subject
to any limits on applicability contained therein, this Article 6 shall survive and continue in full force in accordance with its terms notwithstanding any expiration or termination of this Agreement. 








 ARTICLE 7 
 GENERAL PROVISIONS 
  

	7.1	Entire Agreement 


This Agreement together with Schedules A and B attached hereto when executed by both parties shall constitute the entire agreement
pertaining to the Executive’s employment and supersedes all prior agreements, understandings, negotiations and discussions, whether written or oral, pertaining to the Executive’s employment, and there are no representations, undertakings
or agreements of any, kind between the parties respecting the subject matter hereof except those contained herein. 
  

	7.2	Severability 

 If
any provision of this Agreement is declared void or unenforceable, such provision shall be deemed severed from this Agreement to the extent of the particular circumstances giving rise to such declaration and such provision as it applies to other
persons and circumstances and the remaining terms and conditions of this Agreement shall remain in full force and effect. 
  

	7.3	Representations 


The Executive represents and warrants that (a) he is not a party to any contract, understanding, agreement or policy, whether or not
written, with his current employer (or any previous employer) or otherwise, that would be breached by the Executive’s entering into, or performing services under, this Agreement and (b) will not knowingly use any trade secret, confidential
information, or other intellectual property right of any other party in the performance of his duties hereunder. The Executive will indemnify, defend, and hold each member of the Affiliated Group harmless, from any and all suits and claims arising
out of any breach of such restrictive contracts, understandings, agreements or policies. 
  

	7.4	Notices 

 All
notices and other communications hereunder shall be in writing and shall be given by hand delivery to the other party or by registered or certified mail, return receipt requested, postage, prepaid, addressed as follows: 

If to the Executive: 
 Paul M. Garofolo 
 1436 Mariners Drive 

Newport Beach, California 92660 








 If to the Corporation: 

Attention: 
 Roy
Wieschkowski 
 Patheon Pharmaceutical Services Inc. 
 P.O. Box 110145 
 Research Triangle Park, North Carolina 27709-9998 

or to such other address as either party shall have furnished to the other in writing in accordance herewith. Notice and communications
shall be effective when actually received by the addressee. 
  

	7.5	Withholding 

 The
Corporation may withhold from any amounts payable under this Agreement such Federal, state, local, foreign or other taxes as shall be required to be withheld pursuant to any applicable law or regulation. 

 

	7.6	Waiver 

 The
Executive’s or the Corporation’s failure to insist upon strict compliance with any provision of this Agreement or the failure to assert any right the Executive or the Corporation may have hereunder, including, without limitation, the right
of the Executive to terminate employment for Good Reason, shall not be deemed to be a waiver of such provision or right or any other provision or right of this Agreement. 

 

	7.7	Successors  

  

	 	(a)	This Agreement is personal to the Executive is not assignable by the Executive. This Agreement shall inure to the benefit of and be enforceable by the Executive’s
legal representatives. This Agreement shall inure to the benefit of and be binding upon the Corporation, the other members of the Affiliated Group, and their respective successors and assigns. 


 

	 	(b)	The Corporation will require any successor (whether direct or indirect, by purchase, merger, consolidation or otherwise) to all or substantially all of the business
and/or assets of Patheon or the Corporation to assume expressly and agree to perform this Agreement in the same manner and to the same extent that the Corporation would be required to perform if no such succession had taken place.


  

	7.8	Compliance with Section 409A of the Code 

  

	 	(a)	 It is the Corporation’s intent that the payments and benefits provided under this Agreement shall be exempt from the application of, or otherwise
comply with, the requirements of Section 409A of the Code (“Section 409A). Specifically, any taxable benefits or payments provided under this Agreement are intended to be separate payments that qualify for the “short-term
deferral” exception to Section 409A to the maximum extent possible, and to the extent they do not so qualify, 











	 	 
are intended to qualify for the involuntary separation pay exceptions to Section 409A to the maximum extent possible. This Agreement shall be construed, administered, and governed in a
manner that effects such intent, and the Corporation shall not take any action that would be inconsistent with such intent. Without limiting the foregoing, the payments and benefits provided under this Agreement may not be deferred, accelerated,
extended, paid out or modified in a manner that would result in the imposition of an additional tax under Section 409A upon the Executive. 


  

	 	(b)	If neither the “short-term deferral” or the involuntary separation pay exceptions to Section 409A described above applies to a benefit, payment or
reimbursement under this Agreement, then notwithstanding any provision in this Plan to the contrary, the remaining provisions of this Section 7.8(b) shall apply. 


 

	 	(i)	If the Executive is a “specified employee,” as determined under the Corporation’s policy for identifying specified employees on the Date of Termination,
then to the extent required in order to comply with Section 409A of the Code, all payments, benefits or reimbursements paid or provided under this Agreement that constitute a “deferral of compensation” within the meaning of
Section 409A of the Code, that are provided as a result of a “separation from service” within the meaning of Section 409A and that would otherwise be paid or provided during the first six months following such Date of Termination
shall be accumulated through and paid or provided (together with interest on the delayed amount at the applicable federal rate under Section 7872(f)(2)(A) of the Code in effect on the Date of Termination) within 30 days after the first business
day following the six month anniversary of such Date of Termination (or, if the Executive dies during such six-month period, within 30 days after the Executive’s death). 


 

	 	(ii)	To the extent required to comply with Section 409A Code, any reimbursement of expenses pursuant to Section 2.4(b), 2.4(c) or 3.7, that will not be excluded
from Executive’s income when received is subject to the following requirements: (i) the amount of expenses eligible for reimbursement during a calendar year may not affect the expenses eligible for reimbursement, or in-kind benefits to be
provided in any other calendar year; (ii) the reimbursement of the eligible expense must be made on or before the last day of the calendar year following the calendar year in which the expense was incurred; and (iii) the right to
reimbursement is not subject to liquidation or exchange for another benefit. 

  

	 	(c)	 Although the Corporation shall use its best efforts to avoid the imposition of taxation, interest and penalties under Section 409A of the Code,
the tax treatment of the benefits provided under this Agreement is not warranted or guaranteed. Neither the Affiliated Group nor its directors, officers, employees or advisers shall be held liable for any taxes, interest, penalties or other monetary
amounts owed by the Executive or other taxpayer as a result of the Agreement. Any reference in this Agreement to Section 409A of the Code will also include 











	 	 
any proposed, temporary or final regulations, or any other guidance, promulgated with respect to such Section 409A by the U.S. Department of Treasury or the Internal Revenue Service.



 NOW THEREFORE, the parties below have entered into this Agreement as of the date first written above.

  

									
	PATHEON PHARMACEUTICAL SERVICES INC.
	
	By: Toni T. Sweeney
	Title: Vice President, Human Resources, North America
					
	SIGNED, SEALED AND DELIVERED	 	)	 		 		 	
	 in the presence of
	 	)	 		 		 	
		 	)	 		 		 	
	 /s/ Gwynne A. Kong
	 	)	 		 	 /s/ Paul M. Garofolo
	 	
	Name of Witness:	 		 		 	PAUL M. GAROFOLO	 	









 SCHEDULE A 
 TO 
 EMPLOYMENT AGREEMENT WITH 

PAUL M. GAROFOLO 
 PATHEON INC. 
 POSITION DESCRIPTION 

Chief Information Officer 
 This position description for the Chief Information Officer of the Corporation was enacted by the Chief Executive Officer on May 12, 2008. 
 The Chief Information Officer of the Corporation will have the following functions and responsibilities: 
  

	A.	PLANNING  

  

	 	1.	Lead the Corporation’s strategy for enterprise-wide IT initiatives & global systems management of all IT functions. 


 

	 	2.	Lead the process of preparing annual global IT plans and subsequent forecasts for the Corporation. 


 

	 	3.	Working with operations management, manage the allocation of capital expenditures against approved plans or projects. 


 

	B.	MANAGEMENT 

  

	 	1.	Provide a strong IT and regulatory stewardship for the Corporation, including budgeting, reporting, planning and general IT control management.


  

	 	2.	Responsible for all functions, services and personnel of the Information Technology and Services organization of the Corporation. 


 

	C.	ETHICS, CULTURE, POLICY & PUBLIC REPRESENTATION  

  

	 	1.	Corporate Culture. Foster a North American corporate culture that promotes the Corporation’s core values as reflected in the Corporation’s Code of
Business Conduct. 

  

	 	2.	Work Climate. Maintain a work climate that is conducive to: 

  

	 	(i)	attracting and retaining a diverse group of top-quality employees at all levels; and 


 

	 	(ii)	motivating these employees to perform their duties with the highest standards of integrity, responsibility and excellence; standards that are essential for the success
of a Corporation that provides pharmaceutical product development and manufacturing services worldwide. 









 SCHEDULE B 
 TO 
 EMPLOYMENT AGREEMENT WITH 

PAUL M. GAROFOLO 
 CONFIDENTIALITY UNDERTAKING 
 In consideration of Paul M. Garofolo (the
“Executive”) accepting, an employment agreement between the Executive and Patheon Pharmaceuticals Services Inc. dated May 12, 2008 (the “Agreement”) to which this Confidentiality Undertaking is attached as Schedule B, the
Executive undertakes and covenants with the Affiliated Group (as defined in the Agreement) as follows: 
  

	1.	CONFIDENTIAL INFORMATION 

  

	1.1	Confidential Information 

 The Executive
acknowledges that all information and facts relating to the business and affairs of the Affiliated Group and its customers, including, without limitation, trade secrets, data, notes, marketing plans, sales patterns, and private corporate and
financial information (the “Confidential Information”) is confidential and proprietary to the Affiliated Group and a valuable trade secret of the Affiliated Group, disclosure of which could severely damage the economic interests of
the Affiliated Group. Confidential Information includes, without limitation, any document, work, instrument or other medium assembled or composed by the Executive which contains Confidential Information. 

 

	1.2	Non-Disclosure of Confidential Information  

 The Executive shall not, either during the term of the Agreement or at any time thereafter, use or disclose, directly or indirectly, any of such Confidential Information to any person outside the
Affiliated Group, except where such disclosure is necessary for the proper and bona fide execution of the Executive’s duties under the Agreement, without the prior written consent of the Affiliated Group. The Executive’s obligation not to
use or disclose Confidential Information without prior written consent shall continue to apply after the Executive has ceased to be an employee of the Affiliated Group until such time as the Confidential Information becomes public knowledge through
no fault of the Executive. The Affiliated Group will have full right, title and authority to deal in and with the proprietary rights and the Confidential Information notwithstanding any other provision of the Agreement or the termination thereof for
any reason whatsoever. The Executive acknowledges and agrees that the restrictions contained in this Article 1 are reasonable in the circumstances in order to protect the business of the Affiliated Group. 









	1.3	Return of Confidential Information 


Confidential Information and the documents, works, instruments or other media containing Confidential Information shall remain the property of the
Affiliated Group and be returned to the Affiliated Group upon request or immediately following termination of the Agreement for any reason whatsoever. 
  

	2.	INVENTIONS  

  

	2.1	Inventions 

 Subject to Section 2.2,
the Executive agrees that all discoveries, improvements, designs, ideas or inventions made or conceived, in whole or in part, by the Executive during the term of the Agreement or within three years following termination of the Agreement for any
reason whatsoever (the “Inventions”) shall be the sole property of the Affiliated Group. The Executive shall: 
  

	 	(a)	promptly disclose and describe all such Inventions in writing to the Affiliated Group; 


 

	 	(b)	assign, and the Executive does hereby assign, to the Affiliated Group, without further compensation, all of the Executive’s rights, title and interest in and to
such Inventions and to all applications for letters of patent, copyrights, industrial design or other forms of protection granted for such Inventions throughout the world; 


 

	 	(c)	deliver promptly to the Affiliated Group, upon request and in the form and manner prescribed by the Affiliated Group (without charge to the Affiliated Group but at the
Affiliated Group’s expense) the written instruments described in paragraph (b) and perform such acts as deemed necessary by the Affiliated Group to obtain and maintain such instruments and to transfer all rights and title thereto to the
Affiliated Group; and 

  

	 	(d)	give all assistance that may be required by the Affiliated Group to enable it to protect or exploit the Inventions in any country of the world.


 The Executive does hereby waive in whole any moral rights that the Executive may have in each of the Inventions and any part or
parts thereof, including, but not limited to, the right to the integrity of the Inventions, the right to be associated with the Inventions as its author by name or under a pseudonym and the right to remain anonymous. 

 

	2.2	Excluded Inventions  

 The provisions of
Section 2.1 shall not apply to Inventions which fulfill all of the following criteria: 
  

	 	(a)	Inventions for which no equipment, supplies, facility or Confidential Information belonging to the Affiliated Group were used; and 










	 	(b)	Inventions that do not relate to the business of the Affiliated Group or to the Affiliated Group’s actual or demonstrably anticipated processes, research or
development which the Executive had access to or knowledge of; and 

  

	 	(c)	Inventions that do not result from any work performed by the Executive for the Affiliated Group. 


 

	3.	GENERAL 

 This Confidentiality Undertaking
shall be governed and construed in accordance with the laws of New York State applicable therein. Nothing herein shall be construed so as to limit any obligations owed by you to the Affiliated Group as a matter of common law. The Executive
acknowledges that the business of the Affiliated Group cannot be properly protected from adverse consequences of the Executive’s actions other than by the restrictions set forth in this Undertaking and the Agreement. The Affiliated Group, in
addition to any other right or relief to which it may be entitled, shall be entitled to an injunction restricting further breaches of this Undertaking or the Agreement. This Confidentiality Undertaking shall survive the termination of the Agreement
and the Executive’s employment thereunder. 
 IN WITNESS WHEREOF this Confidentiality Undertaking has been executed by the undersigned on
this 29th day of January, 2009. 
  

									
	SIGNED, SEALED AND DELIVERED	 	)	 		 		 	
	 in the presence of
	 	)	 		 		 	
		 	)	 		 		 	
	 /s/ Gwynne A. Kong
	 	)	 		 	 /s/ Paul M. Garofolo
	 	
	Name of Witness:	 		 		 	               Paul M. Garofolo