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Lassa Fever


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Diagnosis					French																				Related Pages
												liver tissue specimenLassa fever is most often diagnosed by using enzyme-linked immunosorbent serologic assays (ELISA), which detect IgM and IgG antibodies as well as Lassa antigen. Reverse transcription-polymerase chain reaction (RT-PCR) can be used in the early stage of disease. The virus itself may be cultured in 7 to 10 days, but this procedure should only be done in a high containment laboratory with good laboratory practices. Immunohistochemistry, performed on formalin-fixed tissue specimens, can be used to make a post-mortem diagnosis.

			
							
								Page last reviewed:  March 25, 2014						Content source:  	Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of High-Consequence Pathogens and Pathology (DHCPP), Viral Special Pathogens Branch (VSPB) homeLassa Fever
Transmission
Signs & Symptoms
Risk of Exposure
Diagnosis
Treatment
Prevention
Outbreak Distribution Map
Resourcesplus icon
Training: The Epidemiology and Clinical Presentation of Lassa Fever: Information for Medical Providers
Training: Diagnosing and Treating Lassa Fever: Information for Medical Providers
Travelers: U.S. Cases About VSPB (Viral Special Pathogens Branch)


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