2023 Recommended Immunizations for Children from Birth Through 6 Years Old 

VACCINE 

HepB

Hepatitis B 

RV* 

Rotavirus 

DTaP Diphtheria, 

Pertussis, & Tetanus 

Hib* Haemophilus 

influenzae type b 

PCV13, PCV15 

Pneumococcal disease 

IPV 

Polio 

COVID-19** 

Coronavirus disease 2019 

Flu†

Influenza

MMR Measles, 

Mumps, & Rubella 

Varicella 

Chickenpox 

HepA‡

Hepatitis A 

FOOTNOTES 

Number 

of doses 

Two doses given at 

least 4 weeks apart 

Two doses of Hep A vaccine 

are needed for lasting 

Administering a third dose recommended depends on are recommended for children protection. The 2 doses should be given 

at age 6 months depends your child’s age and type age 6 months through 8 years of between age 12 and 23 months. Both 

on the brand of Hib or of COVID-19 vaccine used. age who are getting an influenza doses should be separated by at least 

rotavirus vaccine used for (flu) vaccine for the first time 6 months. Children 2 years and older 

previous dose. and for some other children in who have not received 2 doses of Hep A 

this age group. should complete the series. 

RV* Hib* COVID-19** Flu† HepA‡

MONTH MONTHS MONTHS MONTHS MONTHS MONTHS MONTHS MONTHS YEARS YEARS 

Birth 1 2 4 6 12 15 18

RV RV RV* 

MMR MMR 

Flu (One or Two Doses Yearly)†

HepB HepB HepB 

DTaP DTaP DTaP DTaP DTaP 

Hib Hib Hib* Hib 

PCV PCV PCV PCV 

IPV IPV IPV IPV 

HepA‡ HepA‡

Varicella Varicella 

COVID-19** 

ADDITIONAL INFORMATION 

1. If your child misses 2. If your child has any medical Talk with your 

a shot recommended conditions that put them at child’s doctor if 

for their age, talk to risk for infection (e.g., sickle cell, you have questions 

your child’s doctor as HIV infection, cochlear implants) about any shot 

soon as possible to or is traveling outside the United recommended for 

see when the missed States, talk to your child’s doctor your child. 

shot can be given. about additional vaccines that 

they may need. 

FOR MORE INFORMATION 

Call toll-free: 1-800-CDC-INFO (1-800-232-4636) 

Or visit: cdc.gov/vaccines/parents 

19–23 2–3 4–6
Diseases and the Vaccines that Prevent Them BIRTH–6 YEARS OLD

DISEASE VACCINE DISEASE SPREAD BY DISEASE SYMPTOMS DISEASE COMPLICATIONS 

May be no symptoms, fever, headache, Contact with blood weakness, vomiting, jaundice (yellowing Chronic liver infection, liver failure, liver cancer, death or body fluids of skin and eyes), joint pain 

HepB vaccine protects against hepatitis B. 

Rotavirus RV vaccine protects against rotavirus. 

Hepatitis B 

 

Diphtheria DTaP* vaccine protects against diphtheria. Air, direct contact Sore throat, mild fever, weakness, swollen 

glands in neck 

Swelling of the heart muscle, heart failure, coma, paralysis, 

death 

Pertussis 

(whooping cough) DTaP* vaccine protects against pertussis 

(whooping cough). Air, direct contact Severe cough, runny nose, apnea (a pause in breathing in infants) Pneumonia (infection in the lungs), death 

Tetanus DTaP* vaccine protects against tetanus. Exposure through 

cuts in skin 

Stiffness in neck and abdominal muscles, 

difficulty swallowing, muscle spasms, fever Broken bones, breathing difficulty, death 

Haemophilus 

influenzae 

type b (Hib) 

Hib vaccine protects against 

Haemophilus influenzae type b. 

Pneumococcal 

disease 

(PCV13, PCV15) 

PCV vaccine protects against 

pneumococcal disease. 

Polio IPV vaccine protects against polio. 

Coronavirus 

disease 2019 

(COVID-19) 

COVID-19

vaccine protects against severe 

complications from coronavirus 

disease 2019. 

Influenza (Flu) Flu vaccine protects against influenza. 

Measles MMR** vaccine protects against measles. Air, direct contact Rash, fever, cough, runny nose, pink eye Encephalitis (brain swelling), pneumonia (infection in the 

lungs), death 

Mumps MMR** vaccine protects against mumps. Air, direct contact Swollen salivary glands (under the jaw), 

fever, headache, tiredness, muscle pain 

Meningitis (infection of the covering around the brain and 

spinal cord), encephalitis (brain swelling), inflammation of 

testicles or ovaries, deafness, death 

Rubella MMR** vaccine protects against rubella. Air, direct contact Sometimes rash, fever, swollen lymph nodes Very serious in pregnant women—can lead to miscarriage, 

stillbirth, premature delivery, birth defects 

Through the mouth Diarrhea, fever, vomiting Severe diarrhea, dehydration, death 

Air, direct contact May be no symptoms unless bacteria 

enter the blood 

Meningitis (infection of the covering around the brain and 

spinal cord), intellectual disability, epiglottitis (life-threatening 

infection that can block the windpipe and lead to serious 

breathing problems), pneumonia (infection in the lungs), death 

Air, direct contact May be no symptoms, pneumonia (infection 

in the lungs) 

Bacteremia (blood infection), meningitis (infection of the 

covering around the brain and spinal cord), death 

Air, direct contact, 

through the mouth 

May be no symptoms, sore throat, fever, 

nausea, headache Paralysis, death 

Air, direct contact 

May be no symptoms, fever, muscle aches, 

sore throat, cough, runny nose, diarrhea, 

vomiting, new loss of taste or smell 

Pneumonia (infection in the lungs), respiratory failure, blood 

clots, bleeding disorder, injury to liver, heart or kidney, multisystem inflammatory syndrome, post-COVID syndrome, death 

Air, direct contact Fever, muscle pain, sore throat, cough, 

extreme fatigue 

Pneumonia (infection in the lungs), bronchitis, sinus infections, 

ear infections, death 

Chickenpox Varicella vaccine protects against chickenpox. 

Hepatitis A HepA vaccine protects against hepatitis A. 

DTaP* DTaP combines protection against diphtheria, tetanus, and pertussis. MMR** MMR combines protection against measles, mumps, and rubella. Last updated December 2022 • CS322257-A 

Infected blisters, bleeding disorders, encephalitis (brain Air, direct contact Rash, tiredness, headache, fever swelling), pneumonia (infection in the lungs), death 

Direct contact, May be no symptoms, fever, stomach pain, Liver failure, arthralgia (joint pain), kidney, pancreatic and contaminated food loss of appetite, fatigue, vomiting, jaundice blood disorders, death or water (yellowing of skin and eyes), dark urine