EPA Registration 264‐377  

Vol.2
1

Material to be added to an e-Jacket/Jacket 

Reg. No. )Q,vt - 3;u?-

Descri ption: __ ---"Db-""----_lf.i.." '1-,-,'1-,----,1-",'6...1..1 ___________ _ 

1. 0 Placement within the e-Jacket/jacket: 

w Default: (chronological, top = newest) 

o File location: (PDF page number, i.e., "before page 

45") 

2. 0 Send to Data Extraction contractors this material: 

o Newly stamped accepted label 

a- Notification 

o NewCSF 

o Other: ____________ _ 

3. Attach this coversheet to the top ofthe material or jacket. It 

must be well organized and clipped together, NOT STAPLED. 

Then give the material with this coversheet to staff in the 

Information Services Center (Room S-4900). 

Revi ewer's N arne: _-"=''----_S.L;.c"'''~\t'_''\)__''_k=-_____ _ 

Phone: 3 Lf r MC () Division: ~O , 

I F8 

Date: 

Created August 19, 2008 
2

( 

UNITED STATES ENVIRONMENTAL PROTEC liON AGENCY 

WASHINGTON, DC 20460 

Bayer CropScience 

Laura Phelps 

2 T.W. Alexander Drive 

RTP, NC 27709 

Subject: ETHREL brand Ethephon Plant Growth Regulator 

Registration No.; 264-257 

Date Submitted: 3/14/11 

Decision No.: 447178 

PREP brand Ethephon Plant Regulator for Cotton 

Registration No.; 264-380 

Date Submitted; 3/14111 

Decision No.: 447179 

PREP brand Ethephon for Cotton and Tobacco 

Registration No.: 264-418 

Date Submitted; 3/14111 

Decision No.: 447180 

CERONE brand Ethephon Plant Regulator 

Registration No.: 264-377 

Date Submitted: 3/14111 

Decision No.: 447181 

Dear Ms. Phelps: 

OFFICE OF 

CHEMICAL SAFETY AND 

POLLUTION PREVENTION 

W:.' 1 1 ?Oll 

The Agency is in receipt of your Applications for PestiCide NotifIcation under Pesticide Registration 

Notice (PRN) 98-10. The Registration Division (RD1 has: conducted a review of this request for its 

applicability under PRN 98-10 and finds that the actio-ns requested fall within the scope ofPRN 98-

10. 

The Agency acknowledges the removal of the patent number from the label. 

The label submitted with the application has been stamped "Notification" and will be placed in our 

records. If you have questions concerning this letter, please contact Dominic Schuler at 703-347-0260 or 

via email at schuler.dominic@epa.gov. 

Product ager 22 

Fungicide Branch 

Registration Division (7504P) 
3

PI .... ,..d '".rrut:t/tI". 1m ,...""... b, fOlO COl " ,~ 

Print Form 

Fonn AI) roved .lR No. 2070'()()80 

Unitod Steto. ~ Registration OPf' Id entitlar Numb er 

&EPA Environmental Protection Agency Amendment 

Washington, OC 20460 X Other 

Application for Pesticide - Section I 

1. CornpenylProduct Numb., 2. EPA Product Meneger 3. Propoood Oe .. ificetion 

264-377 Mr. Tony Kish 

DNona o Restricted 4. CompenyIProduc1 (Namo) PM' 

Cerone brand Ethephon plant Regulator 22 

5. Nomo and Addra., of Applicant Ilnclude ZIP Codo' 6. Expedited Review. In accordance with FIFRA Section 31cj{3J 

Bayer CropScience LP (bHiI. my product is similar or identical In composition and labeling 

P. O. Box 12014; 2T. W. Alexander Dr. to: 

Research Trianqle Park, NC 27709 " EPA Reg. No. 

D Check if this is. now _ddr6$$ Product Name 

Section - II 

D Amendmont - Explain beltlw. D Final printed labol, in rasponn ttl 

Agoncy lettar dotod 

D RDSubml .. ion In ,.oponao to Agency lattor datad D "Ma Too" Application. 

~ Notification· Explain below. D Otn.,· Explain below. 

Explanation: U'a additional pagolsllf nlceoaary. (For section I and Section II.) 

Bayer CropScience is submitting a notification for Cerone brand Ethephon plant Regulator to remove the patent number from the label. 

Section - III 

1. Metarial Thie Product Will a. Padr:e;ed In: 

Child'Reeiatent packaging Unit Packeglng Wot., Solublo Packoging 2. Typa of Container By"- By" B y" No No §f't. Plaotic No Gla •• 

, Csrtification must II ·Ye.- No. par If ·Yls· No. per Pep., 

Unit Packaging w"t. containar Package wgt. containor Otner (Specify) be submitttJd , 

3. Location of Nit Contonto Informotien 4. Sizels) Reto~ Containlr 5. Locetion 01 Label Direction. 

0 o Container 

B Onlebol 

Lobel On labe~n" accompanyin" prodUCt 

6. Manner in Which Label ie Affix.d to Product 

~ Utnogreph DOth., 

Peper p'IUod Stenci od 

Section· IV (- (' < , c ,.,-"'" 

1. Contact Point (Ccmpl.,. irfml$ ditecrly b.Jow fot id.ntmclltion tlf individuef to b, lXIntacr.d. if noc.uary. to prtlclI$$ thitt IIppfiCBtiond ,-,;-,-

N~. Titla J ~alepnone No. ,("croiio ARIa Codo) 

Laura Phelps Reg. Affairs Specialist . ( , , ~, , .: ,,, , 

Certification ' " , " , ; < , c" ~ 8. DOla Application , , Rt~':v.,d I cortify that tho statomonts I neve made on this form .nd ell attachments \hareto ere tfUO, occurate and complll'~. c , lacknowlldgo rnet .ny knowingly fol'e or misloading etatemant may ba punisnabla by fine or imprisorvnanfclJch , " ( fStamped) 

both uoo., appllc.blelaw. , , , c <'_ , , 

2. $',ootu,. cJ ~j7..hep5 3. Titlo , 

, " " " 

Regulatol)' Affairs Specialist . (., . 

4. TYPod Nama 5. Dota 

laura Phelps March'4, 2011 

.. EPA Form 8570·1 IRev. 8-94) PrOlllOU' aditiono are eb$ollte. 'NhfW, • EPA file Copy loriglnal) y,lIow • Appllcllnl Cepy 
4

( 

Bayer Crop Science 

March 14,2011 

Document Processing Desk (NOTIF) 

Registration Division (7505P) 

Office of Pesticide Programs 

U.S. Enviromnental Protection Agency 

One Potomac Yard (South Building) 

2777 S. Crystal Drive 

Arlington, VA 22202 

ATTN: Mr. Tony Kish, RD Team 22 

I 

Subject: Cerone brand Ethephon Plant Regulator, EPA Registration. 

No. 264-377; Removal of Patent Number 

Dear Mr. Kish: 

Bayer CropScience is submitting a notification for Cerone brand Ethephon 

Plant Regulator to remove the patent number from the label. 

This notification is consistent with the provisions ofPR Notice 98-10. No 

other changes have been made to the labeling or the Confidential Statement of 

Formula for this product. I understand that it is a violation of 18 U.S.C. 

Section 1001 to willfully make any false statement,to EPA. I further 

understand that if the amended label is not consistent with the requirements of 

40 CFR §§156.l0, 156.140, 156.144, 156.146 and'156.156, this product may 

be in violation ofFIFRA and 1 may be subjected to, enforcement action and 

penalties tmder Section 12 and 14 ofFIFRA". 

Enclosed are an EPA Form 8570-1 and one copy of the revised Cerone brand 

Ethephon Plant Regulator label for review. 

Please contact me if you should have further questions. 

Sincerely, 

Bayer CropScience 

P. O. Box 12014 

2, T, W. Alexander Drive 

Research Triangle Park, NC 27709 

,(, , 

, , , 

, " ( " 

" , " ' 

(" , , " , ,', , 

'" ' 

Laura Phelps , " " 

Regulatory Affairs, Herbicides & PGRs 
5

Bayer Crop Science 

Bayer CropScience 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919-549-2302 

mobil:919-352-8075 

email: Iaura.phelps@bayer.com 

," , "( ( 

, , , 

'( (, 

, 
6

NC • ,FICATION 

MAY 1 1 2011 

CERONE® brandETHEPHON Plant Regnlator 

For Reducing Lodging in Barley, Wheat and Grasses Grown for Seed 

For Agricultural or Commercial Use Only, Not For Residential Use. 

ACTIVE INGREDIENT: Ethephon (2~chloroethyl) phosphonic acW ........................................................................ 39.9% 

INERT INGREDIENTS: ............................................................................................................................................... 60.1 % 

"Contains 4 pounds ethephOn per gallon 

EPA Reg. No. 264-377 EPA EST NO. 264·MO·002 

KEEP OUT OF REACH OF CHILDREN 

DANGER PELIGRO 

Si usted no entiende la eliquela, busque a alguien para que se la explique a usted en detalie. 

(If you do not understand the label, find someone to explain it to you in detail.) 

For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1-800434-7577 

For PRODUCT USE Information Call1-866-99BAYER (1-866-992-2937) 

FIRST AID 

IF ON SKIN OR • Take off contaminated clothing. 

CLOTHING: • Rinse skin immediately with plenty of water for 15-20 minutes. 

• Call a Doison control center or doctor for treatment advice. 

IFIN EYES: • Hold eye open and rinse slowly and gently with water for 15-20 minutes. 

• Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. 

• Call a poison control center or doctor for treatment advice. 

IF SWALLOWED: • Immediately call a poison control center or doctor for treatment advice. 

• Do not induce vomiting unless told to do so by a poison control center or doctor. 

• Have person Sip a glass of water if able to swallow. 

• Do not give anything by mouth to an uncOnscious person. 

For MEDICAL Emergencies Call 24·liours A Day 1-800_334-75n. 

Have the product container or label with you when calling a poison control center or doctor or going for treatment. 

NOTE TO PHYSICIAN: Treat symptomatically. Consideration should be given to the possibility that overexposure to materials 

other than this product may have occurred. No specific antidote is available. Probable mucosal damage may contraindicate the use 

of Qastric lavag·e. 

PRECAUTIONARY STATEMENTS 

DANGER 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

Corrosive. Causes irreversible eye damage and skin irritation. Harmful if swallowed or absorbed thrOl,l;]ll 5:(;1'1. Do not g~t in eyes, on 

skin or on clothing. 

PERSONAL PROTECTIVE EQUIPMENT (PPE) 

Applicators and other handlers must wear long-sleeved shirt and long pants, chemical resistant gloves IT'<'Cl? ('f any wat3:proot material 

(such as Nitrile, Butyl, Neoprene and/or Barrier Laminate), shoes plus socks and protective eyewear. 

Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this products .:;C)nr.~ntrate. Do 

not reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washabllos, use detergent 

and hot water. Keep and wash PPE separately from other laundry. 

1 
7

i 

When handlers use closed systems, enclosed cabs, or aircraft in a manner thai meets the requirements listed in the Worker Protection 

Standard (WPS) for agricultural pesticides [40 CFR 170.240 (d) (4-6)], the handler PPE requirements may be reduced or modified as 

specified in the WPS. 

User Safety Recommendations 

Users should wash hands before eating, drinking, chewing gum, using tobacco or using the toile!. 

Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and put on clean clothing. 

Users should remove PPE immediately aller handling this product. As soon as possible, wash thoroughly and change into clean 

clolhina. Wash the outside of gloves before removinQ. 

ENVIRONMENTAL HAZARDS 

Do not apply directly to water, ar to. areas where surface water is present ar to. intertidal areas belaw the mean high water mark. Do nat 

cantaminate water when dispasing of equipment washwaters. Do. nat cantaminate water used far irrigatian ar damestic purposes. 

Avaid spray drift to. nearby crops as this product will cause madificatians in plant growth. Plant injury ar reduced yields may result. 

IMPORTANT: Do. nat use this praduct far purpases ather than thase listed an the label. 

SPRAY DRIFT 

Avaid spray drift. Do. nat apply when weather canditians may cause drift. Do. nat allaw this product to drift an to non-target areas. Drift 

may result in illegal residues ar injury to. adjacent crops and vegetation, in the farm af leaf yellawing and defaliatian. To. avoid spray 

drift, DO NOT apply aerially when wind speed is greater than 10 mph ar during periads af temperature inversians. Use of larger droplet 

size will also. reduce spray drift. 

AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. 

The interactian af many equipment-and-weather-related factors determine the potential far spray drift. The applicatar is respansible far 

cansidering all these factars when making decisians. 

The fallawing drift management requirements must be fallowed to. avaid aff-target movementtrom aerial applications to. agricultural field 

crops. These requirements do. nat apply to. farestry applicatians, public health uses or to. applicatians using dry formulatians. 

1. The distance 0.1 the auter mast nazzles an the baam must not exceed 3f4the length af the wingspan ar rotar. 

2. Nozzles must always point backward parallel with the air stream and never be painted dawnwards more than 45 degrees. 

Where states have mare stringent regulatians, they shauld be observed. 

The applicatar shauld be familiar with and take into accauntthe infarmatian covered in the Aerial Drift Reductian Advisary below: 

AERIAL DRIFT REDUCTION ADVISORY 

[This sectian is advisary in nature and daes not supersede the mandatory label requirements). 

INFORMATION ON DROPLET SIZE 

The mast effective way to reduce drift patential is to. apply large draPlets. The best drift management strategy is to. apply the largest 

draplets that provide sufficient coverage and co.ntrol. Applying larger droplets reduces drift patential, but will nat prevent drift if 

applicatians are made improperly, or under unfavarable environmental canditians (See Wind, Temperature and Humidity, and 

Temperature Inversians). 

CONTROLLING DROpLET SJZE 

Volume - Use high flow rate nazzles to. apply the highest practical spray volume. Nazzles with higher rated flaws praduce larger 

droplets. 

Pressure - Do nat exceed the nozzle manufacturer's recammended pressures. Far many nazzle types lawer pressure rr')r1uces larger 

draplets. When higher flaw rates are needed, use higher flaw rate nazzles instead af increasing pressure. 

Number af nazzles - Use the minimum number af nazzles that provide unifarm caverage. 

Nazzle Orientatian - Orienting nazzles so that the spray is released parallel to the airstream produces larger droplets than ather 

arientatians and is the recammended practice. Significant deflect ian fram harizantal will reduce draplet &, .. 6 <t! '0 increase orift patentiaL 

Nozzle Type - Use a nozzle type that is deSigned far the intended applicatian. With mast nazzle types, narrawer sprat <..r,;;:E..S produce 

larger draplets. Consider using laW-drift nazzles. Salid stream nazzles ariented straight back produce 'he 'argest droplets and the 

lowest drift. 

BOOM LENGTH 

Far same use patterns, reducing the effective baam length to. less than 3f4 af the wingspan ar ratar length may ft::iher ~educe drift 

withaut reducing swath width. 

APPLICATION HEIGHT 

Applicatians shauld nat be made at a height greater than 10 feet abave the tap of the target plants unless a greater height is required 

for aircraft safety. Making applicatians at the lawest height that is safe reduces expasure af droplets to. evaporatian and wind. 

2 
8

( 

SWATH ADJUSTMENT 

When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges of the 

field, the applicator should compensate for this displacement by adjusting the path of the aircraft upwind. Swath adjustment distance 

should increase, with increasing drill potential (higher wind, smaller drops, etc.). 

WIND 

Drift potential is lowest between wind speeds of 2 • 10 mph. However, many factors, including droplet size and equipment type 

determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high 

inversion potential. NOTE: local terrain can influence wind pattems. Every applicator should be tamiliar with local wind patlems and 

how they affect spray drift. 

TEMPERATURE AND HUMIDITY 

When making applications in low relative humidity, set up equipment to produce larger droplets to compensate for evaporation, Droplet 

evaporation is most severe when conditions are both hot and dry. 

TEMPERATURE INVERSIONS 

Applications should not occur during a temperature inversion because drift potential is high. Temperature inversions restrict vertical air 

mixing, which causes small suspended droplets to remain in a concentrated cloud. This doud can move in unpredictable directions due 

to the light variable winds common during inversions. Temperature inversions are characterized by increasing temperatures with 

altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue 

into the moming. Their presence can be indicated by ground fog; however, if fog is not present, inversions can also be identified by the 

movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated 

cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical 

air mixing. 

SENStTtVE AREAS 

The pesticide should only be applied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies of water, 

known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive 

areas). 

GENERAL INFORMATION 

CERONE® brand Ethephon Plant Regulator is intended for use as a lOdging reduction agent in barley and wheat crops and in grasses 

grown for seed production. Use CERONE@only on vigorously growing crops that are likely to lodge. Do not use CERONE® In nonlodging situations or where lodging causes only minimal yield loss. 

lodged crops increase harvest costs and decrease harvest efficiency and recoverable yields. lodging can cause uneven maturity, 

higher moisture content and loss of grain quality. In grasses grown for seed lodging at anthesis can reduce seed set and yield. 

CERONE® brand Ethephon Plant Regulator decomposes in the plant to release ethylene, a naturally occurring plant hormone. 

CERONe® increases stem strength thereby increasing the plant'S resistance to lOdging. CERONe® may shorten the plant depending 

on variety, environmental conditions and the rate used. CERONE®·also reduces 'necking" in barley and yield decreases due to 

shattering and head loss. 

DIRECTIONS FOR USE 

It is a violation of Federal Law to use this product in a manner inconsistent with its labelIng. 

Do not apply this product in a way that wIll contact workers or other persons, either directly or through drift. Only protected 

handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the agency 

responsible for pesticide regulations. 

Read entire label before using this product. 

3 
9

AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains 

requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural 

pesticides. It contains requirements for training, deconlaminallon, notification, and emergency assistance. Jt also contains specific 

instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notification to workers 

and restricted-entry intervals. The requirements in this box only apply to uses of this product thai are covered by the Worker Protection 

Standard. 

Do not enter or allow worker enl ry into treated areas during the restricted-entry interval (REJ) of 48 hours. The REI is 72 hours in areas 

where average rainfall is less than 25 Inches per year. 

PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with 

anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, chemical resistant 

gloves made of any waterproof materials such as nitrile, butyl, neoprene, or barrier laminte, chemical resistant footwear plus socks, and 

protective eyewear. For overhead exposure, chemical-resistant headgear is also required, 

Notify workers of the application by warning them orally and posting warning signs at entrances to treated areas. 

STORAGE AND DISPOSAL 

STORAGE 

Do not contaminate water, food, or feed by storage or disposal. 

If container is broken or contents have spilled, follow all precautions indicated above and clean up immediately. Before cleaning up, put 

on full-length trousers, long-sleeved shirt, protective gloves and goggles or face-shield. Soak up spill with absorbent media such as 

sand, earth or other suitable material and dispose of waste at an approved waste disposal facility, 

PESTICIDE DISPOSAL 

Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of Federal law. If 

these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Waste representative at the nearest EPA Regional Office for guidance. 

CONTAINER DISPOSAL 

Do not reuse empty container. Triple rinse or equivalem, Then offer for recycling or reconditioning or puncture and dispose of in a 

sanitarv landfill, or bv incineration, or if allowed bv state and local authorities, bv bumina. If burned, stav out of smoke. 

USE LIMITATIONS 

Do not apply through any type of irrigation system. 

Yield or quality decreases may occur if CERON~ brand Ethephon Plant Regulator is not properly used. 

Allow 7 days after application for lodging reduction activity to begin. "-' CERON~ brand Ethephon Plant Regulator is not effective on 

crops already lodged. 

Disease infestations (rust, septoria, mildew, etc.) may be affected by CERON~ brand Ethephon Plan! Regulator use. Use a tungicide 

control program where needed. 

Temperature, moisture or disease stress at application or after CERONE® brand Ethephon Plant Regulator use can result in yield loss. 

CERONE® brand Ethephon Plant Regulator use in non-lodging situations may result in yield loss. 

Observe temperature limitations on this label at application. 

CERONE® brand Ethephon Plant Regulator may delay heading 1 to 2 days and harvest maturity 1 to 4 d.:!~. Extreme temperatures 

(below 35°F or above 85°F in non-irrigated or 90°F in irrigated crops) within 5 days after application may cause further mr:t:.d:y delay. 

Do not use on late seeded crops in short season growing areas because possible maturity delay may caUStl ha, vest difficIJlti~s. 

CERONE® brand Ethephon Plant Regulator treatment may increase secondary tillers in some spring br:r~EY:> especialJ}" und&r moisture 

or temperature stress. 

Do not use CERONEil brand Ethephon Plant Regulator on AzUre barley or Tyler wheat. 

Do not apply CERONE® brand Ethephon Plant Regulator if rain is expected w'dhin 6 hours. 

DO NOT GRAZE OR FORAGE TREATED CROP OR CUT FOR HAY OR SILAGE. Mature straw at normal harvest rr,ay be consumed 

by animals. 

4 
10

Do not plant another crop within 30 days after treatment. 

TREATMENT DECISION GUIDE 

Important- Inspect fields just prior to application to determine the probability of lodging. Use CERONE® brand Ethephon Plant 

Regulator only under the following conditions: 

1. The crop is expected to lodge and significant loss 01 recoverable yield, grain quality, and/or harvest efliciency is expected. 

2. The crop is free of stress lrom disease or insect damage. 

3. Soil moisture or irrigation is adequate to prevent crop stress after application. 

4. Temperature fluctuations (below 35° F or above 85° F non-irrigated and 900 F irrigated) are not expected lor 5 days after 

application. 

5. Application can be made at the correct stage. Feekes 8 to 10 - see growth stage chart. 

SPRAY PREPARATION 

Add 1/2 to 3/4 of the required amount of water to the spray tank and begin agitation. Add the required amount of CERONE® brand 

Ethephon Plant Regulator followed by the remaining amount of water. Prepare only as much spray solution as can be used on the day 

of mixing. Use of previous day's spray mix may result in reduced activity. 

Do not spill the concentrated product on spray eqUipment, or any airplane parts. Any spilfs should be rinsed Immediately with 

plenty of water as CERONE® brand Ethephon Plant Regulator is corrosive. Use of a nurse tank is recommended to avoid possible 

spills of concentrated formulation on spray equipment or airplane parts. 

EQUIPMENT CLEANING 

Because 01 the acidic nature of this product, prolonged exposure to spray deposits will damage acrylic plastics, certain paints, and 

metals. Rinse thoroughly with a detergent and water all exposed acrylic plastic-type materials (e.g., aircraft windshields), and painted 

surfaces within an hour after exposure to spray deposits. At the end of each day, rinse thoroughly with a detergent and water the 

spray system and all the metal parts 01 the aircraft exposed to the spray depOSits. 

WHEAT AND BARLEY 

COMPATIBILITY 

CERONe1D brand Ethephon Plant Regulator can be tank-mixed with approved cereal insecticides and fungicides. Treatment is 

intended as a preventive measure. Insecticide and fungicide treatment programs should be based on timely scouting and economic 

threshold assessments. This may not coincide with CERONE® application timing. Do not use CERONE® as a tank mixture with 

insecticides or fungicides on crops stressed by adverse weather conditions, referenced above, or by insect or disease damage. 

Crop Injury or yield loss may result with tank mix application under stress conditions. (i.e. moisture, heat, cold, insect, 

dIsease). CERONE® + TIn® tank mix application by air made under stress conditfons may result in flag leaf bum and yIeld 

loss. . 

Do not tank mix with herbicides or nitrogen solutions. 

Do not add adjuvants, surfactants or wefting agents to CERONE®brarid Ethephon Plant Regulator. 

APPLICATION TIMING 

Apply when the flag leaf is just visible to boot stage, but before the awns have emerged or the sheath has split (Feekes-Large Scale 

8-10, Zadok's Code 37-45). Do not allow spray solution to contact exposed heads, as damage and reduced yield may result. Inspect 

fields carefully to determine that application can be made at the proper stage. 

APPLICATION 

For CERONE® brand Ethephon Plant Regulator to be effective temperature after application should be at least GO°F. 

Avoid spray overlap which can result in excess rate and yield loss. 

GROUND: Use a minimum of 7 gallons of water per acre when applied by conventional ground eq'liprren~. Flat Ian nozzles are 

recommended. Use a minimum of 5 gallons of water per acre with controlled droplet application {COA} or air foil typ~ !!q·J·F~ent. To 

prevent uneven application adjust spray boom to plant canopy height and operate at moderate speed. 

AIR: Use a minimum of 3 gallons of water per acre. 

USE RATES 

Lodging pressure and environmental conditions will affect the CERONE® brand Ethephon Plant Regulator rate needed. 

On more responsive varieties use only the 0.5 pint per acre rate. Consult your state extension specialist or Bayer CropScience 

representative for more inlormation. 

Do not apply more than a total of 1.0 pint (0.5 lb. active) of CERON~ brand Ethephon Plant Regulator per acre per year. 

Do not harvest wheat or barley within 40 days of last CERONE® brand Ethephon Plant Regulator application. 

5 
11

CERONE" RATE GUIDE FOR BARLEY AND WHEAT 

EXPECTED LODGING PRESSURE 

(CERONE" PINTS/ACRE) 

SITUATION MODERATE HEAVY SEVERE COMMENTS 

Barley 1/2 tJ2 to 3/4 3/4to1~ Some lall varieties with vigorous growth may require 

SprinQ and winter} 1 pint per acre. 

Winter Wheat 1/2 1/2 to 3/4 314101~ In severe lodging situations, these rates may not be 

adequate to control lodging in some tall straw 

varieties such as "Rouahrider' and 'Aoassiz". 

Most Spring wheals 1/2 1/2 S/4 In severe lodging situations, these rates may not be 

adequate to conlrollodging in some tall durum 

High Temperature~* or 1/2 1/2 1/2 wheats such as 'Vic", 

Sensitive Variety 

NON-IRRIGATED BARLEY AND WHEAT 

CO NOT apply CERONE® brand Ethephon Plant Regulator to non-irrigated barley and wheat in states west of the Mississippi 

River except: 1) in the Sacramento Valley and west of the Coastal Range in California and, 2) west of the Cascade Range in 

Washington and Oregon. 

CERONE® brand Ethephon Plant Regulator is recommended in the non-irrigated areas in states east of the Mississippi River and 1) in 

Sacramento Valley and west of the Coastal Range in Califomia, and 2) west of the Cascade Range in Washington and Oregon. 

IRRIGATED BARLEY AND WHEAT 

Irrigation prior to treatment is recommended to avoid stress and may be resumed 24 hours after treatment If conditions are hot and dry 

continue irrigation through the grain head filling period. 

Moisture and/or heat stress during anthesis and grain fill can cause significant yield loss. With CERONE® brand Ethephon Plant 

Regulator, it is important to avoid plant stress during these growth periods in order to obtain optimum yield and quality. 

RESTRICTIONS AND LIMITA nONS 

~ Limit use of the 1.0 pint rate to situations where lodging is expected to result in a high loss of yield potential: 1) an irrigated crop with 

unusually severe lodging pressure, 2) very tall lodging prone variety, or 3) a cereal type such as durum known to be subject to severe 

lodging. 

~~ Do not use CERONP'> brand Ethephon Plant Regulator if daytime temperatures for the period 5 days after application are expected 

to exceed 85° F in non-irrigated or 90° F in irrigated wheat or barley crops. 

6 
12

Growth 

Description 

Feeks - 7 

Large Scale 

Zadok's 32 

Code 

CERONE Too 

treatment time Early 

CERONE® APPLICATION STAGE CHART 

8 9 

37 39 

GROWTH STAGE 

CHART 

swoJJen 

to 

45 

10.1 

50 

Too 

Late 

completed 

10.4 

57 

7 
13

GRASS SEED PRODUCTION 

(DO NOT USE IN CALIFORi\'IA) 

In grasses grown for seed, lodging prior to pOllination can reduce yield and halVest efficiency. CEAONE® brand Elhephon Plant 

Regulator increases the plant's resistance to lodging providing the potential for improved seed set al anlhesis. CEAONE® use can also 

improve harvesl efficiency and recoverable yield. Where early lodging is expected, a spUt application may be benelicial. Apply 1 P'lnt at 

growth stage 8, lo!!owed by I pint at growth stage 10 to 10.3. 

CERONE· RATE GUIDE FOR GRASS SEED PRODUCTION' 

LODGING PRESSURE 

(Pints/Acre) 

Moderate Heavy Severe 

1 1.5 2 

• See specifiC directions for split applications. 

COMPATIBILITY 

APPliCATION STAGE COMMENTS 

(Feekes Scale) 

Apply between lale boot and when spike half 

10-10.3 emerged trom sheath. Do not apply after 30% 

of spikes have completed emergence from the 

sheath . 

CERONE® brand Ethephon Plant Regulator may be tank mixed with fungicides approved tor use on grasses. Tank mix applications 

must tollow all label directions tor each product used. 

USE PRECAUTIONS 

Do not graze or forage treated tields. 

Do not use treated seed screenings as animal feed. 

8 
14

IMPORTANT: READ BEFORE USE 

Read the entire Directions for Use, Conditions, Disclaimer of Warranties and limitations of liability before using this product. If lenns 

are not acceptable, return the unopened product container al once. 

By using this product, user or buyer accepts the following Conditions, Disclaimer of Warranl'les and Um·llalions of liabinly. 

CONDITIONS: The directions for use of this product are believed to be adequate and should be followed carefully. However, it is 

impossible to eliminate all risks associated with lhe use of this product. Crop iniury, ineffectiveness or other unintended consequences 

may result because of such lactors as weather conditions, presence 01 other materials, or the manner of use or application, all of which 

are beyond the control of Bayer CropScience. All such risks shall be assumed by the user or buyer. 

DISCLAIMER OF WARRANTIES: BAYER CROPSCIENCE MAKES NO OTHER WARRANTIES, EXPRESS OR IMPLIED, OF 

MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR OTHERWiSE, THAT EXTEND BEYOND THE 

STATEMENTS MADE ON THIS LABEL. No agent of Bayer Cropscience is authorized to make any warranties beyond those contained 

herein or to modify the warranties contained herein. BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR 

SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. 

LIMITATIONS OF LIABILITY: THE EXCLUSIVE REMEDY OF THE USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR 

DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, 

NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT EXCEED THE PURCHASE PRICE PAID, OR AT BAYER 

CROPSCIENCE'S ELECTION, THE REPLACEMENT OF PRODUCT. 

r.:tY Bayer Crop Science 

Bayer CropScience LP 

P.O. Box 12014, 2 T.W. Atexander Drive 

Research Triangle Park, North Carolina 27709 

1-866-99BA YER (1-866-992-2937) 

Tilt is a registered trademark of Ciba-Geigy Corp. 

CERONE® brand Ethephon Plant Regulator (MASTER) Approved 11/18102, Notification 03lt4/2011 

9