FINAL – February 26, 2014

Page 1 of 2 

ACIP

MEETING OF THE ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES (ACIP)

Centers for Disease Control and Prevention

1600 Clifton Road, NE, Tom Harkin Global Communications Center (Building 19), Atlanta, Georgia

February 26-27, 2014 

AGENDA ITEM PURPOSE PRESIDER/PRESENTER(s)

Wednesday, February 26th

8:00

 

Welcome & Introductions Dr Jonathan Temte (Chair, ACIP)

Dr Larry Pickering (Executive Secretary, 

ACIP, CDC)

8:30 Influenza

• Brief announcement: novel influenza vaccine work group

• Introduction 

• Influenza activity update

• Interim estimates of 2013-14 seasonal influenza vaccine 

effectiveness

• Effectiveness of LAIV vs. IIV for health children (GRADE)

• Interim influenza vaccine safety update: LAIV and IIV in 

persons <18 years of age

• LAIV vs. IIV comparative safety studies in children

• Safety of LAIV vs. IIV for healthy children (GRADE)

• LAIV update

• Proposed recommendations

Information 

Discussion

Vote 

Dr Douglas Campos-Outcalt (ACIP)

Dr Ruth Karron (ACIP, WG Chair)

Dr Lyn Finelli (CDC/NCIRD)

Dr Brendan Flannery (CDC/NCIRD)

Dr Lisa Grohskopf (CDC/NCIRD)

Dr Maria Cano (CDC/NCEZID)

Dr Emmanuel (Chip) Walter (Duke 

University Medical Center)

Dr Lisa Grohskopf (CDC/NCIRD)

Dr Kathleen Coelingh (MedImmune)

Dr Lisa Grohskopf (CDC/NCIRD)

10:45 Break

11:15 Meningococcal Vaccines

• Introduction 

• Meningococcal disease among men who have sex with men 

(MSM)

• Meningococcal disease and vaccine response in HIVinfected persons

• Use of serogroup B meningococcal vaccine during outbreaks 

on college campuses 

Information 

Discussion

 

Dr Lorry Rubin (ACIP, WG Chair)

Ms Jessica MacNeil (CDC/NCIRD)

Ms Jessica MacNeil (CDC/NCIRD)

Dr Manisha Patel (CDC/NCIRD) 

12:30 Lunch

13:45 Pneumococcal Conjugate Vaccine (PCV) 

• Introduction 

• Update on PCV13 effectiveness and herd effects in the U.S.

• Reduced dose schedules of PCV13 for children: GRADE of 

evidence

• PCV13 reduced dose schedules for children: considerations 

and WG conclusions

Information 

Discussion

Dr Nancy Bennett (ACIP, WG Chair)

Dr Matt Moore (CDC/NCIRD)

Ms Sara Tomczyk (CDC/NCIRD) 

Dr Tamara Pilishvili (CDC/NCIRD)

15:45 Break

16:15 Yellow Fever Vaccine

• Introduction 

• Background: yellow fever disease, yellow fever vaccine, and 

recent vaccine developments

Information 

Discussion

Dr Joseph Bocchini (ACIP, WG Chair)

Dr J. Erin Staples (CDC/NCEZID)

17:30 Vaccine Supply Information Dr Jeanne Santoli (CDC/NCIRD)

17:45 Public Comment

18:00 Adjourn
FINAL – February 26, 2014

Page 2 of 2 

ACIP

AGENDA ITEM PURPOSE PRESIDER/PRESENTER(s)

Thursday, February 27th

8:00 Agency Updates 

CDC, CMS, DoD, DVA FDA, HRSA, IHS, NVPO, NIH

8:15 General Recommendations

• Vaccine storage and handling Information 

Discussion 

Dr Jeff Duchin (ACIP, WG Chair)

Dr Andrew Kroger (CDC/NCIRD)

9:00 Safety of Tetanus, Diphtheria, and Acellular Pertussis (Tdap)

Vaccine 

• Introduction 

• Safety of Tdap vaccine during pregnancy: enhanced 

surveillance in VAERS

• Tdap during pregnancy: safety and coverage data from the 

VSD

Information 

Discussion

Dr Arthur Reingold (ACIP, WG Chair)

Dr Pedro Moro (CDC/NCEZID)

Dr Elyse O Kharbanda (HealthPartners 

Institute for Education and Research)

09:45 Break

10:15 Human Papillomavirus (HPV) Vaccine 

• Introduction 

• HPV type attribution in cervical precancers

• HPV-associated cancers and type attribution

• 9-valent HPV vaccine clinical trial data

• Summary and next steps

Updated ACIP statement-bivalent and quadrivalent vaccines

Information 

Discussion

Vote 

Dr Joseph Bocchini (ACIP, WG Chair)

Dr Susan Hariri (CDC/NCHHSTP)

Dr Mona Saraiya (CDC/NCCDPHP)

Dr Alain Luxembourg (Merck)

Dr Lauri Markowitz (CDC/NCHHSTP)

12:15 Smallpox Vaccine

• Introduction 

• Use of ACAM2000 smallpox vaccine in laboratory personnel

Information 

Discussion

Dr Lee Harrison (ACIP, WG Chair)

Dr Brett Petersen (CDC/NCEZID)

13:00 Public Comment

13:15 Adjourn

Acronyms

CDC Centers for Disease Control & Prevention

CMS Centers for Medicare and Medicaid Services 

DOD Department of Defense

DVA Department of Veterans Affairs

FDA Food and Drug Administration

GRADE Grading of Recommendations Assessment, Development and Evaluation

HRSA Health Resources and Services Administration

HIS

IIV

LAIV

Indian Health Service

Inactivated Influenza Vaccine

Live-Attenuated Influenza Vaccine

NCHHSTP National Center for HIV, Hepatitis, STD and TB Prevention [of CDC/CCID] 

NCIRD CDC National Center for Immunization & Respiratory Diseases [of CDC/CCID] 

NCZVED National Center for Zoonotic, Vector-Borne, and Enteric Diseases [of CDC/CCID]

NIH National Institutes of Health

NVPO National Vaccine Program Office

SMART

VAERS 

VSD

Strategic Multi-Attribute Ranking Tool for vaccines

Vaccine Adverse Event Reporting System

Vaccine Safety Datalink

WG Work Group