Final Meeting Agenda (02/17/2006) 

ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES 

Centers for Disease Control and Prevention 

1600 Clifton Road, NE, Building 19, Room 232 

Atlanta, Georgia 

February 21-22, 2006 

8:30 Human Papillomavirus Vaccine (HPV Vaccine)

Introduction 

 

Overview - HPV 

HPV epidemiology in the US 

Brief review of cervical cancer in US 

GSK HPV vaccine clinical trial data 

Merck HPV vaccine clinical trial data 

Cost-effectiveness of HPV vaccine 

Mathematical modeling – HPV vaccine 

Behavioral issues related to use of HPV vaccine

Recommendation options

AGENDA ITEM 

Tuesday February 21 

8:00 Welcome

PURPOSE/ACTION 

Information/discussion 

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PRESIDER/PRESENTER(s) 

Dr. J. Abramson (Chair, ACIP)

Dr. L. Pickering (CDC, OD

Dr. Janet Gilsdorf (Chair, HPV 

 Vaccine Working Grp) 

Dr. Doug Lowy (NCI) 

Dr. Eileen Dunne (CDC/DSTD) 

Dr. Herschel Lawson (CDC/DCPC) 

Dr. Gary Dubin (GSK) 

Dr. Eliav Barr (Merck) 

Dr. Harrell Chesson (CDC/DSTD) 

Dr. Geoff Garnett (Imperial College) 

Dr. Nicole Liddon (CDC/DSTD) 

Dr. Lauri Markowitz (CDC/DSTD)

10:30 BREAK

11:00 HPV Vaccine, continued from topics above Information/discussion continued from speakers, above 

1:00 LUNCH

2:00 Rotavirus Vaccine (RV)

 Introduction 

 

Brief review of data from REST Trial 

Brief review of cost-effectiveness data 

Data from physician & provider surveys on 

use of rotavirus vaccine 

Post-licensure surveillance plans (esp intussusception) 

 

 Recommendations 

Dr. John Treanor (Chair, RV

 Working Grp)

Dr. P. Heaton (Merck) 

Dr. M. Widdowson (CDC/NCID) 

Dr. Allison Kempe 

Dr. P. Haber (CDC/OCSO) 

Dr. C. Mast (Merck) 

Dr. U. Parashar (CDC/NCID)

Dr. G. Wallace (CDC/NIP)

 

Information/discussion 

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Vote 

Possible VFC V ot

4:00 BREAK

4:30	 General Recommendations on Immunization Information, discussion & vote Dr. E. Marcuse (ACIP) 

Dr. A. Kroger (CDC/N IP) 

 

 

6:00 Public Comment 

6:15 ADJOURN 

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Information/discussion

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Information, discussion 

& vote 

VFC Vote

Information/discussion 

 

 

 

 

 

 

Final Meeting Agenda (02/17/2006) 

AGENDA ITEM 

Wednesday February 22 

PURPOSE/ACTION PRESIDER/PRESENTER(s) 

8:00 Unfinished Business Dr. J. Abramson (Chair, ACIP)

8:20 VZIG Update: availability of a new product Information Dr. M. Marin (CDC/NIP) 

8:30 Influenza 

Influenza overview 

Review of the Jan 2006 Influenza Vaccine 

 Summit Meeting 

Update on virologic surveillance, U.S. 

Update on antiviral drug resistance

Influenza disease burden in children 0-5 yrs

Changes to the 2006 ACIP influenza 

 vaccine recommendations 

Update on pandemic influenza preparedness 

 

Dr. B. Allos (ACIP) 

Dr. L.J. Tan (AMA) 

Dr. A. Klimov (CDC/NCID) 

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Dr. K. Poehling (Vanderbilt)

Dr. N. Smith (CDC/NCID) 

 

Dr. G Wallace (CDC/NIP)

Dr. B. Gellin (NVPO) 

Dr. G. Curlin (NIH)

10:30 BREAK

11:00 Tetanus Toxoid, Diphtheria Toxoid and Acellular Pertussis (Tdap) Vaccines 

Report from the Pertussis Working Group 

Tdap for health care workers 

Cost-benefit analysis of Tdap vaccination 

 of HCW 

Standard of care, program, proposed Tdap 

 recommendation for HCW

Tdap for adults 65+ years of age 

Information 

Information 

Information 

Information, discussion, vote 

 

Information, discussion, vote 

Dr. D. Morse (ACIP) 

Dr. T. Tiwari (CDC/NIP) 

Dr. I. Ortega-Sanchez (CDC/NIP)

Dr. T. Murphy (CDC/NIP) 

 

Dr. K. Kretsinger (CDC/NIP) 

12:30 LUNCH

1:30 Herpes Zoster Vaccine

Zoster vaccine shipping, storage 

Physician survey on H Zoster vaccine 

Shingles prevention trial

Information/discussion 

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Dr. R. Harpaz & team (CDC/NIP)

Dr. G. Wallace (CDC/NIP) 

Dr. A. Kempe (U. Colorado) 

Dr. P. Annunziato (Merck) 

3:00 Classification of the Evidence Base 

 for Recommendations of the U.S. ACIP

Information/discussion Dr. D. Fishbein (CDC/NIP) & 

Dr. S. Manning (CDC/NIP)

Ms. M. Lindley (CDC/N

3:30 Public Comment 

3:45 Adjourn

2 
Final Meeting Agenda (02/17/2006) 

3 This document can be found on the CDC website at: 

http://www.cdc.gov/vaccines/recs/acip/downloads/agenda-feb06.pdf