Support Documents for 

Significant New Use Rule (SNURs) on 

Premanufacture Notices (PMNs) 

P-10-517 and P-10-518 

EPA Docket EPA-HQ-OPPT-2011-0577 

EPA SANITIZED Page 1 of 47
Index

A-001 Structure Activity Team (SAT) Report for 

PMNs P-10-517 and P-10-518 

A-002 Initial Review Engineering Report for 

PMNs P-10-517 and P-10-518 

A-003 Initial Review Exposure Report for 

PMNs P-10-517 and P-10-518 

EPA SANITIZED Page 2 of 47
A-001 

Structure Activity Team (SAT) Report

 for PMNs P-10-517 and P-10-518

EPA SANITIZED Page 3 of 47
 

EPA SANITIZED Page 4 of 47
 

EPA SANITIZED Page 5 of 47
 

 

 

 

 

 

 

 

 

 

 

EPA SANITIZED Page 6 of 47
 

 

 

 

 

 

 

 

EPA SANITIZED Page 7 of 47
 

 

 

 

 

 

 

 

 

EPA SANITIZED Page 8 of 47
 

 

EPA SANITIZED Page 9 of 47
 

EPA SANITIZED Page 10 of 47
EPA SANITIZED Page 11 of 47
 

 

 

 

EPA SANITIZED Page 12 of 47
 

 

 

 

 

 

EPA SANITIZED Page 13 of 47
 

 

 

 

 

 

EPA SANITIZED Page 14 of 47
 

 

 

 

EPA SANITIZED Page 15 of 47
 

 

 

 

EPA SANITIZED Page 16 of 47
 

 

EPA SANITIZED Page 17 of 47
 

EPA SANITIZED Page 18 of 47
EPA SANITIZED Page 19 of 47
EPA SANITIZED Page 20 of 47
 

 

 

 

 

 

 

 

 

 

EPA SANITIZED Page 21 of 47
 

 

 

 

 

EPA SANITIZED Page 22 of 47
 

 

 

 

EPA SANITIZED Page 23 of 47
 

EPA SANITIZED Page 24 of 47
 

 

 

 

EPA SANITIZED Page 25 of 47
 

EPA SANITIZED Page 26 of 47
A-002 

Initial Review Engineering Report

 for PMNs P-10-517 and P-10-518

EPA SANITIZED Page 27 of 47
EPA SANITIZED Page 28 of 47
EPA SANITIZED Page 29 of 47
EPA SANITIZED Page 30 of 47
 

EPA SANITIZED Page 31 of 47
 

 

EPA SANITIZED Page 32 of 47
 

EPA SANITIZED Page 33 of 47
 

EPA SANITIZED Page 34 of 47
 

EPA SANITIZED Page 35 of 47
EPA SANITIZED Page 36 of 47
A-003 

Initial Review Exposure Report

 for PMNs P-10-517 and P-10-518

EPA SANITIZED Page 37 of 47
10/27/2010 Page 1 of 10 

POST FOCUS EXPOSURE REPORT 

 Chemical ID: P-10-0517 Reviewer: Kwon/BC 

 

Results Table: Dose, Concentration, and Days Exceeded Results Summary 

Exposure 

Scenario1 

 Water Landfill Stack Air Fugitive Air 

Drinking Water Fish Ingestion 

ADR LADD ADR LADD 7Q104 

CC = 

20 

PDM 

Days 

Exceeded

LADD ADR LADD ADR LADD 

Release 

activity(ies)2; 

exposure 

calculation(s)

3 

mg/kg/day mg/kg/day mg/kg/day mg/kg/day μg/l # Days mg/kg/day mg/kg/day mg/kg/day mg/kg/day mg/kg/day 

MFG: max 

acute eco 

USE 1: Max 

ADR 

USE 1: Max 

LADD 

1 Exposure scenario titles consist of release activity followed by exposure calculation abbreviation. 

2 Release activities are from engineering report's Manufacturing (Mfg), Processing (Proc) and Use release activity 

labels. Multiple release activities are combined in one exposure scenario if their releases occur at same location. 

3 Exposure calculations are Acute Dose Rate (ADR), Lifetime Average Daily Dose (LADD), and Probabilistic 

Dilution Model (PDM). There may be one, two, or all three exposure calculations per exposure scenario. 

 CC is the aquatic concentration of concern. 

4 This column displays concentration values for the 7Q10 streamflow, which is defined as the average daily 

streamflow of the seven consecutive days of lowest flow within a ten year period. 

Remarks: 

1 Down-the-Drain Module within NCEM2 model. 

2 Consumer Exposure Module within NCEM2 model. 

EPA SANITIZED Page 38 of 47
10/27/2010 Page 2 of 10 

Fate test recommendations?: (default is NA)

EPA SANITIZED Page 39 of 47
10/27/2010 Page 3 of 10 

 POST FOCUS EXPOSURE REPORT 

Chemical ID: P-10-0517 Assessor: Kwon/BC 

ENVIRONMENTAL RELEASES 

 Scenario#:1 Number of Release Sites: 

 Release Activity: MFG: Max ADR 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 

Per Site Release: 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 

EPA SANITIZED Page 40 of 47
10/27/2010 Page 4 of 10 

POST FOCUS EXPOSURE REPORT 

 Chemical ID: P-10-0517 

EPA SANITIZED Page 41 of 47
10/27/2010 Page 5 of 10 

 POST FOCUS EXPOSURE REPORT 

Chemical ID: P-10-0517 Assessor: Kwon/BC 

ENVIRONMENTAL RELEASES 

 Scenario#:2 Number of Release Sites: 

 Release Activity: USE 1: Max ADR 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 

Per Site Release: 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 

EPA SANITIZED Page 42 of 47
10/27/2010 Page 6 of 10 

POST FOCUS EXPOSURE REPORT 

Chemical ID: P-10-0517 

EPA SANITIZED Page 43 of 47
10/27/2010 Page 7 of 10 

EPA SANITIZED Page 44 of 47
10/27/2010 Page 8 of 10 

 POST FOCUS EXPOSURE REPORT 

Chemical ID: P-10-0517 Assessor: Kwon/BC 

ENVIRONMENTAL RELEASES 

 Scenario#:3 Number of Release Sites: 

 Release Activity: USE 1: Max LADD 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 

Per Site Release: 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 

EPA SANITIZED Page 45 of 47
10/27/2010 Page 9 of 10 

POST FOCUS EXPOSURE REPORT 

Chemical ID: P-10-0517 

EPA SANITIZED Page 46 of 47
10/27/2010 Page 10 of 10 

EPA SANITIZED Page 47 of 47