Final - June 20, 2023

8:00 Welcome & Introductions Dr. Grace Lee (ACIP Chair)

Dr. Melinda Wharton (ACIP Executive Secretary, CDC)

8:30 Respiratory Syncytial Virus Vaccines - Adult

Introduction

Manufacturer presentation: Pfizer season 2 safety & efficacy; 

coadministration with influenza vaccine

Manufacturer presentation: GSK season 2 safety & efficacy; 

coadministration with influenza vaccine

Updated cost-effectiveness of the Pfizer and GSK vaccines 

(main CDC model)

Comparison of cost effectiveness results of the main CDC 

model and each manufacturer model (Pfizer & GSK)

Updated EtR (incl. GRADE) and clinical considerations for 2 

vaccines (Pfizer & GSK)

Dr. Camille Kotton (ACIP, WG Chair)

Dr. Alejandra Gurtman (Pfizer)

Dr. Leonard Friedland (GSK)

Dr. David Hutton (University of Michigan)

Dr. Ismael Ortega Sanchez (CDC/NCIRD)

Dr. Michael Melgar (CDC/NCIRD)

11:45 Break

12:45 Polio Vaccine

Introduction

Recommendations for Adult Polio Vaccination

Dr. Oliver Brooks (ACIP, WG Chair)

Dr. Sarah Kidd (CDC/NCIRD)

2:15 Break

2:30 Influenza Vaccines

Introduction

WG considerations and proposed recommendations

Dr. H. Keipp Talbot (ACIP, WG Chair)

Dr. Lisa Grohskopf (CDC/NCIRD)

4:00 Break

4:15 Public Comment

4:35 VOTES 

RSV Adult Vaccines

Polio Vaccine

Influenza Vaccines

VFC VOTE

Influenza Vaccines

Dr. Michael Melgar (CDC/NCIRD)

Dr. Sarah Kidd (CDC/NCIRD)

Dr. Lisa Grohskopf (CDC/NCIRD)

Dr. Jeanne Santoli (CDC/NCIRD)

5:30 Adjourn

MEETING OF THE ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES (ACIP)

Centers for Disease Control and Prevention

Atlanta, Georgia 30329 

June 21-23, 2023

Wednesday, June 21, 2023
Final - June 20, 2023

8:00 Welcome & Introductions Dr. Grace Lee (ACIP Chair)

Dr. Melinda Wharton (ACIP Executive Secretary, CDC)

8:35 Agency Updates

CDC, CMS, FDA, HRSA, IHS, OIDP, NIH

8:55 Pneumococcal Vaccines

Introduction

Economic analysis and public health impact of PCV20 use in 

children

Comparison of cost-effectiveness analyses on PCV20 use in 

children

Summary of WG interpretation on EtR and policy options

Dr. Kathy Poehling (ACIP, WG Chair)

Dr. Charles Stoecker (Tulane University)

Dr. Ayabina Diepreye (CDC/NCIRD)

Dr. Miwako Kobayashi (CDC/NCIRD)

10:25 Break

10:40 Dengue Vaccines

Introduction

Introduction of policy questions for TAK-003

Cost effectiveness analysis and health impacts of routine 

vaccination with TAK-003 dengue vaccine in Puerto Rico

Summary of two economic models for dengue vaccine TAK003 use in Puerto Rico

Partial EtR framework for TAK-003

Dr. Wilbur Chen (ACIP, WG Chair)

Dr. Alfonso Hernandez (CDC/NCEZID)

Dr. Guido Espana (University of Notre Dame)

Dr. RajReni Kaul (CDC/NCIRD)

Dr. Joshua Wong (CDC/NCEZID)

11:40 Break

12:25 Chikungunya Vaccine

Introduction

Value of chikungunya vaccine to U.S. travelers and providers

Chikungunya virus infection among laboratory workers 

Update on large chikungunya outbreak in Paraguay

Workgroup plans and timelines 

Dr. Beth Bell (ACIP, WG Chair)

Ms. Nicole Lindsey (CDC/NCEZID)

Dr. Susan Hills (CDC/NCEZID)

Dr. Susan Hills (CDC/NCEZID)

Dr. Susan Hills (CDC/NCEZID)

1:25 Break

1:40 Respiratory Syncytial Virus Vaccines - Pediatric/Maternal

Introduction

Economic analysis of RSVpreF in pediatric populations

EtR Pfizer maternal RSV vaccine

Economic analysis of combined use of nirsevimab and 

maternal RSVpreF vaccine

Clinical considerations for RSV maternal vaccine and 

nirsevimab

Dr. Sarah Long (ACIP, WG Chair)

Dr. David Hutton (University of Michigan)

Dr. Katherine Fleming-Dutra (CDC/NCIRD)

Dr. David Hutton (University of Michigan) 

Dr. Jefferson Jones (CDC, NCIRD)

4:40 Break

4:50 Public Comment

5:10 VOTES 

Pneumococcal vaccines

VFC VOTE

Pneumococcal Vaccines

Dr. Jeanne Santoli (CDC/NCIRD)

Dr. Jeanne Santoli (CDC/NCIRD)

5:30 Adjorn

Thursday, June 22, 2023
Final - June 20, 2023

8:00 Welcome & Introductions Dr. Grace Lee (ACIP Chair)

8:10 Mpox Vaccine

Introduction

Updates From the 2022/2023 U.S. Mpox Outbreak: 

Epidemiology, Vaccine Safety, and Vaccine Effectiveness

Use of JYNNEOS During Mpox Outbreaks: Clinical guidance 

Dr. Pablo Sanchez (ACIP, WG Chair)

Dr. Faisal Minhaj (CDC/NCEZID)

Dr. Agam Rao (CDC/NCEZID)

Considerations for Long-term Protection Against Mpox Dr. Agam Rao (CDC/NCEZID)

10:10 Break

10:20 Meningococcal Vaccines

Introduction

Cost effectiveness analysis

GRADE/EtR

Summary and workgroup considerations

Dr. Kathy Poehling (ACIP, WG Chair)

Dr. Ismael Ortega-Sanchez (CDC/NCIRD)

Dr. Sam Crowe (CDC/NCIRD)

Dr. Sam Crowe (CDC/NCIRD)

11:35 Break

11:45 Vaccine Safety

The childhood immunization schedule and safety: Studies in 

the Vaccine Safety Datalink

Preliminary evaluation of aluminum content in childhood 

vaccines and risk of asthma in a Danish nationwide cohort

Dr. Tom Shimabukuro (CDC/NCEZID)

Dr. Matthew Daley (Kaiser Permanente Colorado)

Dr. Anders Hviid (Statens Serum Institut, Copenhagen, 

Denmark)

12:30 Break

12:40 COVID-19 Vaccines 

Introduction

Updates to COVID-19 epidemiology and vaccine effectiveness

Infection-induced and hybrid immunity

Summary and work group considerations

Dr. Matthew Daley (ACIP WG Chair)

Dr. Fiona Havers (CDC/NCIRD), Dr. Romeo Galang 

(CDC/NCCDPHP), Dr. Ruth Link-Gelles (CDC/NCIRD)

Dr. Jefferson Jones (CDC/NCIRD)

Dr. Megan Wallace (CDC/NCIRD)

2:40 Adjorn

Acronyms

CDC

CMS Centers for Medicare and Medicaid Services 

COVID-19 Coronavirus disease 2019

EtR Evidence to Recommendations Framework

FDA Food and Drug Administration

GRADE

HRSA Health Resources and Services Administration

IHS Indian Health Service

NCHHSTP

NCIRD

NCEZID

NIAID

OIDP Office of Infectious Disease and HIV/AIDS Policy

SARS-CoV-2 Severe Acute Respiratory Syndrome Coronavirus 2

WG Work Group

WHO World Health Organization

VE Vaccine Effectiveness

Friday, June 23, 2023

National Institute of Allergy and Infectious Diseases

Centers for Disease Control and Prevention

Grading of Recommendations Assessment, Development and Evaluation

National Center for HIV, Hepatitis, STD and TB Prevention [of CDC/OID] 

National Center for Immunization & Respiratory Diseases [of CDC/OID] 

National Center for Emerging and Zoonotic Diseases [of CDC/OID]