Skip directly to site content Skip directly to search


Español  Other Languages


Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People
 Search
		×
			Vaccines site
			Vaccines site
				All CDC
				Submit
			For a full list of topics:A-Z Index
			Advanced Search
		Advanced Search


Immunization Information Systems (IIS)


Facebook
        Twitter
        LinkedIn
        Syndicate





Immunization Gateway Overview										Related Pages
										The Immunization Gateway (IZ Gateway) is a portfolio of components that share a common IT infrastructure. These components support the exchange of immunization data between immunization information systems (IISs), provider organizations, and consumer applications. The IZ Gateway can streamline time- and resource-intensive data exchange onboarding. It also replaces multiple one-to-one connections with centralized routing. This page includes an overview of each component, including the requirements and benefits of participating in each one.
Acronyms Related to the IZ GatewayAIRA – American Immunization Registry Association
ASTHO – Association of State and Territorial Health Officials
APHL – Association of Public Health Laboratories
AWS – Amazon Web Services
BAA – Business Associate Agreement
CDC – Centers for Disease Control and Prevention
DUA – Data Use Agreement
FISMA – Federal Information Security Modernization Act
HIPAA – Health Insurance Portability and Accountability Act
HL7 – Health Level Seven International
IIS – Immunization Information System
MOU – Memorandum of Understanding
WSDL – Web Services Description LanguageLegal Agreements
Each component of the IZ Gateway has different legal requirements for participation. Regulatory and legal changes might be necessary in some jurisdictions to use the IZ Gateway. Participating jurisdictions should begin reviewing their current agreements and these requirements now to determine what may need to be added.
Data Use Agreement – Jurisdiction IIS and APHLAllows data to flow through the IZ Gateway, which is hosted by APHL
Addresses security, responsibilities, parties’ relationship, amendment, and incident response
No renewal required
APHL holds the signed DUAsInterjurisdictional MOU – Jurisdiction IIS and Jurisdiction IISPublic Health Interjurisdictional MOU (updated August 2019)
Signed among public health jurisdictions
Allows data exchange to occur through the IZ Gateway or an alternative mechanism with any state or jurisdiction that has signed the MOU
Not a federal agreement, only between signatories
No renewal required
AIRA holds the signed MOUsBusiness Associate Agreement – Provider Organization and APHLRecognizes that the IZ Gateway sends and receives data on behalf of the provider organization
Addresses disclosure and use of protected health information, security, privacy, incident response, and other clauses
No renewal required
Required by HIPAA
APHL holds the signed BAAsJurisdiction-Specific Policy Agreement(s) (e.g., provider site agreements, confidentiality agreements, etc.) – Jurisdiction IIS and Provider OrganizationSpecific to each jurisdiction
Signed by provider organizationCDC is determining if an additional legal agreement will be needed to allow U.S. government authorized users to access deidentified data.IZ Gateway Information SheetIZ Gateway Awardee Forum: Deep Dive Q&As
							
					
						Page last reviewed:  August 22, 2021					Content source: 	National Center for Immunization and Respiratory Diseases homeIIS Home
About IIS
Functional Standardsplus icon
Version 4.1
Core Data Elementsplus icon
Core Data Elements For IIS Functional Standards v4.0
Historical Core Data Elements
Data Code Setsplus icon
CVX
CVX Mapped to Vaccine Groups
CVX Mapped to VIS
MVX
Product Name Mapped to CVX/MVX
NDC Crosswalk Tables
VIS Barcode Lookup Table
VIS URL Table
CPT Mapped to CVX
Fall Season Respiratory Vaccine Codes
IIS Technical Guidanceplus icon
HL7
Transport (SOAP)
Deduplication
Clinical Decision Support for Immunization (CDSi)plus icon
CDSi Training Material
IZ Gatewayplus icon
Overview
Information Sheet
Awardee Forum Q&As
Meaningful Use
Vaccine 2D Barcodesplus icon
Vaccine 2D Barcoding for Manufacturers
Vaccines Shipping with 2D Barcodes
Vaccine 2D Barcode Scanning for Vendors
Vaccine 2D Barcode Scanning Initiatives
Vaccine 2D Barcode Scanning Implementation Toolkit
CDC IIS Activitiesplus icon
MIROW
NIS-IIS Collaboration
Sentinel Sites
IIS Strategic Planplus icon
2018-2020
2014-2017
Contacts for IIS Immunization Records
IIS Policy and Legislation
IIS Annual Report (IISAR)plus icon
Overview
Participation Rates and Maps
MMWR Articles on Annual Report Data
IISAR Survey Data
IIS Training
Resources & Reference Materialsplus icon
Acronyms
Conferences & Events
Frequently Asked Questions
Functional Standards Resource Guide
Partner Organizations
Publications
Sustainability Resources National Center for Immunization and Respiratory Diseases
Centers for Disease Control and Prevention
1600 Clifton Road NE, Building 24
Mailstop A-19
Atlanta, GA 30333
iisinfo@cdc.gov
 Vaccines & ImmunizationsCDC Meaningful UseVaccine Tracking System (VTrckS)Vaccines for Children Program (VFC)Vaccine Management Business Improvement Project (VMBIP)Comprehensive Clinic Assessment Software Application (CoCASA)


About CDC
					Contact Us
					800-232-4636
 Facebook Twitter Instagram LinkedIn Youtube Pinterest Snapchat
 CONTACT CDC
				Contact Us
							Call 800-232-4636
							Email Us
			ABOUT CDC
				About CDC
							Jobs
							Funding
			POLICIES
				Accessibility
							External Links
							Privacy
							Policies
							No Fear Act
							FOIA
							OIG
							Nondiscrimination
							Vulnerability Disclosure Policy
			CONNECT WITH US
				Facebook
								Twitter
								Instagram
								LinkedIn
							Youtube
								Pinterest
								Snapchat
								Email
			LANGUAGES
				Español
							繁體中文
							Tiếng Việt
							한국어
							Tagalog
							Русский
							العربية
							Kreyòl Ayisyen
							Français
							Polski
							Português
							Italiano
							Deutsch
							日本語
							فارسی
							English


U.S. Department of Health & Human Services
			Accessibility
			External Links
			Privacy
			Policies
			No Fear Act
			FOIA
			Nondiscrimination
			OIG
			Vulnerability Disclosure Policy
			USA.gov


Exit Notification / Disclaimer Policy Close
 Links with this icon  indicate that you are leaving the CDC website. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website.
				Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website.
				You will be subject to the destination website's privacy policy when you follow the link.
				CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Website Disclaimers
 Cancel Continue