FINAL – June 18, 2010

1 

MEETING OF THE ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES (ACIP)

Centers for Disease Control and Prevention

1600 Clifton Road, NE, Tom Harkin Global Communications Center (Building 19), Atlanta, Georgia 

June 23-24, 2010

AGENDA ITEM PURPOSE PRESIDER/PRESENTER(s)

Wednesday, June 23, 2010

8:00

 

Welcome & Introductions

 

Dr. Carol Baker (Chair, ACIP)

Dr. Larry Pickering 

 (Executive Secretary, ACIP; CDC) 

8:30 Evidence Based Recommendations 

 Introduction: ACIP implementation of an explicit 

evidence-based recommendation format

 Professional organization perspectives on 

development and endorsement of recommendations

 GRADE (Grading of Recommendations, Assessment,

 Development and Evaluation)

 WHO’s Strategic Advisory Group of Experts (SAGE): 

approach to evidence-based recommendations

 Pilot of explicit evidence-based framework based on

 GRADE

Information

& 

Discussion

Information

& 

Discussion

Dr. Jonathan Temte 

 (ACIP, WG Chair)

AAFP: Dr. Doug Campos-Outcalt

AAP: Dr. Joseph Bocchini

ACP: Dr. Gregory Poland

Dr. Holger Schünemann

 (McMaster University, Canada)

Dr. Arthur Reingold (UC Berkeley 

SPH, SAGE Member)

Dr. Faruque Ahmed (CDC/NCIRD)

10 :45 Break

11:15 Meningococcal Vaccine

 Introduction

 Guillain-Barré Syndrome (GBS) after receipt of 

Menactra

 Update on monitoring of GBS after receipt of

 meningococcal conjugate vaccines

 Meningococcal conjugate vaccines and GBS

 Update on meningococcal vaccination program

Information

& 

Discussion

Vote

Dr. Cody Meissner (ACIP, WG Chair)

Dr. Priscilla Velentgas 

 (Harvard Pilgrim)

Mr. Eric Weintraub (CDC/NCEZID)

Dr. Amanda Cohn (CDC/NCIRD)

Dr. Amanda Cohn (CDC/NCIRD)

12:30 Lunch

1:30 Human Papillomavirus (HPV) Vaccines

 HPV vaccine update Information

& 

Discussion

Dr. Lauri Markowitz 

(CDC/NCHHSTP)

1:45 Hepatitis Vaccines

 Update on Hepatitis Vaccines Work Group

 Trends in acute hepatitis B virus (HBV) disease

 Hepatitis B risk among persons with and without 

diabetes mellitus

 Hepatitis B vaccine safety and seroprotection rates 

among persons with diabetes mellitus

 Preview of proposed recommendations; request for 

additional information

Information

& 

Discussion

Dr. Mark Sawyer (ACIP, WG Chair)

Dr. Ruth Jiles (CDC/NCHHSTP)

Dr. Dale Hu (CDC/NCHHSTP)

Dr. Philip Spradling (CDC/NCHHSTP)

Dr. Trudy Murphy (CDC/NCHHSTP)

3:30 Break
FINAL – June 18, 2010

2 

3:45 Pertussis Vaccines

 Update on Pertussis Vaccines Work Group activities

 Update on the Pertussis Vaccine Program

Information

& 

Discussion

Dr. Mark Sawyer (ACIP, WG Chair)

Dr. Jennifer Liang (CDC/NCIRD)

4:30 13-Valent Pneumococcal Conjugate Vaccine (PCV13)

 PCV13 VFC correction VFC vote Dr. Lance Rodewald (CDC/ NCIRD)

4:45 Vaccine Supply

 Update on vaccine supply Information

Discussion

Dr. Lance Rodewald (CDC/ NCIRD) 

5:00 Public Comment

5:15 Adjourn

Thursday, June 24, 2010

8:00 Agency Updates (CDC, CMS, DOD, DVA, FDA, HRSA, IHS, 

NIH, NVAC, NVPO)

Information ACIP Ex Officio Members

8:15 Influenza Vaccines 

 Introduction

Influenza season update and summary

 Influenza vaccine effectiveness

 Influenza Vaccine Work Group update

 Vote on number of doses of seasonal vaccine 

required for children age <9 years who received 

no prior 2009 H1N1 monovalent vaccine

 VFC vote

 2009 pandemic H1N1 monovalent vaccine safety 

studies

Information

& 

Discussion

Information

Discussion

Vote

VFC Vote

Information

& 

Discussion

Dr. Kathy Neuzil (ACIP, WG Chair)

Dr. Tony Fiore (CDC/NCIRD)

Dr. David Shay (CDC/NCIRD)

Dr. Anthony Fiore (CDC/NCIRD)

Dr. Lance Rodewald (CDC/NCIRD)

Dr. Frank DeStefano (ISO/NCEZID)

Dr. Tracy Lieu (Harvard Pilgrim)

Dr. Hector Izurieta (CBER/FDA)

10:45 Break

11:00 Respiratory Syncytial Virus (RSV) Immunoprophylaxis 

 Introduction

 Epidemiology of RSV infections

 History of RSV immunoprophylaxis

 Summary

Information

Information

& 

Discussion

Dr. Lance Chilton (ACIP, WG Chair)

Dr. Gayle Fischer Langley 

(CDC/NCIRD)

Dr. Cody Meissner (ACIP Member)

Dr. Lance Chilton (ACIP, WG Chair)

12:15 Lunch

1:15 Health Care Reform and its Implications for National 

Immunization Policy and Practice

Information Attorney Sara Rosenbaum 

(ACIP Member)

1:45 Rotavirus Vaccines

 Update on porcine circovirus in rotavirus vaccines Information

Discussion

Dr. Umesh Parashar (CDC/NCIRD)

Dr. Margaret Cortese (CDC/NCIRD)

Dr. Wellington Sun (FDA)

Dr. Len Friedland (GSK)

Ms. Kim Dezura (Merck)

3:15 Public Comment

3:30 Adjourn
FINAL – June 18, 2010

3 

Acronyms

ACIP Advisory Committee on Immunization Practices

CDC Centers for Disease Control & Prevention

CMS Centers for Medicare and Medicaid Services 

DBD Division of Bacterial Diseases [of NCIRD]

DOD Department of Defense

DGMQ Division of Global Migration and Quarantine

DHQP Division of Healthcare Quality Promotion

DSTDP Division of Sexually Transmitted Diseases Prevention [of NCHHSTP]

DVA Department of Veterans Affairs

DVBID Division of Vector-Borne Infectious Diseases

DVD Division of Viral Diseases [of NCIRD]

DVH Division of Viral Hepatitis [of NCHHSTP]

DVRD Division of Viral and Rickettsial Diseases

FDA Food and Drug Administration

GID Global Immunization Division

HHS Health & Human Services

HRSA Health Resources and Services Administration

ID Influenza Division [of NCIRD]

IHS Indian Health Service

ISD Immunization Services Division [of NCIRD]

ISO Immunization Safety Office (of CDC/OD/Office of the Chief Science Officer)

NCHHSTP National Center for HIV, Hepatitis, STD and TB Prevention [of CDC/CCID] 

NCIRD CDC National Center for Immunization & Respiratory Diseases [of CDC/CCID] 

NIH National Institutes of Health

NVAC National Vaccine Advisory Committee

NVPO National Vaccine Program Office

OCSO Office of the Chief Science Officer

OD Office of the Director [of CDC]

OS Office of the Secretary

TBD To be determined

WG Work Group

This document can be found on the CDC website at: http://www.cdc.gov/vaccines/recs/acip/downloads/agenda-jun10.pdf