UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON O

. C

. , 20460



## JUL 15 2015 OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION



### MEMORANDUM
SUBJECT : FROM:

THRU:

TO :

# ~:::::~:::**P:fi:.~::: ::~:::::•tion**  

# Revie: rb :**'.~~ ;:**  £? Biological Analysis Branch

## ~!J'ff**~**



# -**R~fael** A. Prieto, _Environmental.Protection

### Specialis**~L/** 

# A.**f~** Science lnfonnation and Analysis Branch 

### fl · 

# 7 ·- - l · 

### Andrew Lee , Economist

# ~**(~** Economic Analysis Branch

- - · Biological and Economic Analysis Division (7503 P) ArnetJones , Chief
.

## tf..-/'/'/?~**~Av~~** Biological Analysis Brancy.....- / cV"t< 

### ..5 Diann Sims, Chief

# 41-"~

# f J)_ .)._,'frv'v Science lnfonnation and ka1y f. s Brancl1 Timothy Kiely, Chief 

# 2**\j\A_~** Economic Analysis Branch Biological and Economic Analy s Division (7 Khue Nguyen , Chemical Review Manager Risk Management and Implementation Branch 1 Pesticide Re-evaluation Division (7508P)


### Peer Review Panel date: July 8, 2015

### SUMMARY Ferbam was first regi stered 

### in 1948
. Ferbam is a dithiocarbamates fungicide (FRAC Code M3). It has multi

- site contact activity against fungi. Ferbam is mainly used on grapefruits and oranges in Florida to control scab disease. Based on private market usage data (2009

- 2012), approximately 22,000 lbs a. i. (92% of the total fungicides use) of ferbam was applied to g rapefruits and oranges in Florida It is a lso used on mangoes 

### in Florida as special local need to control anthracnose di sease. 

### INTRO D UCTION The Biological and Economic Analysis Divi s ion (BEAD) Chemical Profile (BCP) provides an overview of the pest management roles and quantitative usage information for ferbam. The BCP includes summaries of previous BEAD products and availab le public and/or private use and usage data for ferbam to describe the ro le ofthi s chemical 

### in pest management. Additional information on u se i s avai lable in the Label Data Reports for ferbam. Information provided in this BEAD Chemical Profile (BCP) may be used by stakeholders (e.g. , users and registrants), OPP risk assessors , and OPP risk managers , and the general public during the Registration Review process of this pesticide. 

### USE SITES Registered agricultural use sites for ferbam are: app les, citrus (grapefruit, limes , lemons , oranges, tangerines, and tang e los) , cranberries, pears, peaches , nectarines , and mangoes (sp ecial local nee d)
. The re are no known regi stered non-agricultural use si te s for ferbam. 

### FORMULATIONS AND APPLI CATION METHODS Ferbam is formu lated as a water dispersib le granules and applied as a ground boom spray or as a spot treatment. 

### HISTORY OF FERBAM BEAD PRO DUCTS A search of the BEAD database for previou s BEAD products for ferbam indicates that there are no records of prior BEAD benefits assessments or Section 18 Emergency Exemption Requests for ferbam
. Recent Section 18 Emergency Exemption Requests might suggest that a chemical is important for the use s granted in the request ; however, a lack of Section 1 8 Emergency Exemption Requests is not an indication of the relative importance of the chemical. 

### USAGE Agricultural For years 2004-2008, ferbam annual usage averaged 57 , 000 pounds of active ingre dient (A. I.) treating an annual average of 14 , 000 acres, with an overall average app lication rate of4.1 pound s A. I. per acre. For the 2009-2012 timeframe , fe rbam annua l usage averaged 24,000 pounds of A. I.
2treating an annual ave rage o f 3 , 500 acre s , and w ith an overall average appli c ation rate of 6.9 pound s A
. 

### I. per acre. No usage wa s reported in proprietary data for year 2013. The use of ferbam , both in terms of pounds A. I. and in terms oftotal area treate d (TAT) , has been decreasing since 2004 , with minimal usage , both in term s ofpounds and in term s of total area treated , in the la st few years (fig ure 1 )
. ( Proprietary Data, 2009-2012) Us age Trend s 

### FIGURE 1. 

### Ferbam Pounds A. I. 

### Applied and Tota l Area Treated (TAT) in Acres (2004

- 2012) 1 3 0, 0 0 0

-- Lb s

...,._ TAT 35,000
411 QI 

## ... I.I 

### < .E

'

. t='

### ~ ..:

0 <;T 0 0 N L/'I 8 N l.O 8 N ,.._ 0 0 N 00 

### 8 N Yea r 

# 8 N ...... ..... 0 N Source: Proprietary Data , 2004-2012 "O QI 

# ... ra QI 

## ... .... ra QI 

## ... < iii 

# ... 0


## .... 0 N
..... 0 N

A s shown in table s 1 , 2 , and 3 below, for the mo st recent years of data, 2009-2012 , grapefruit and oranges are ferbam ' s top crops , with grapefruit having a 53% of usage in terms of total pounds applied. Florida is the top state for ferbam 's use , with 92% of u s a ge in terms oftotal pounds A. I. appli e d. TAB 

### LE 1. 

### Crops with Highest Use of Ferbam

- Percent of Tota l Lbs. Aoolied (2004-20 12) 2004

- 2008 2009-2012 

### Crop %Lbs Crop %Lbs Grapefruit 5 2 Grapefruit 53

Orange s 34 Oranges 39 Other* 14 Other* 8 *Othe r crops may include cherries, apples, and peaches . 

### Source: Prop r ietary Data, 2004

- 2012

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### TABLE 2. States with 

# u· h t U f F b 1 e: es se o e r am- p 

### t f 

### T t l Lb
. Applied (20 09-2012) ercen o oa s State O/o 

### Florida 92 Michigan 8 Sou r ce: Prop r ietary Data, 2009

- 2012 · 

### Application Rates As seen on table 3 below , the application rates for ferbam ' s top crops (in terms of both pounds and TAT) , do not vary much , from 7.3 1 for grapefruit up to 7.92 for oranges. TABLE3 F b U 

# . er am se on T C 

### op rops: A

### verage A 

### nnua lU 

### "th A I R t 2009 2012 sage w 1 

# . . a e, 

## - Crop Average Ann ua l Average Annual Avg. A. I. 

### Rate Total Pou nds Total Acres T r eated* (lbs A. I./ Acre) Grapefruit 13 , 000 2,000 7.31

Orange 9 , 000 1 ,0 00 7.92 *Total Acres Treated s ums all acres treated for a crop, including those acres that receive multiple treatments. Source: EPA Proprietary Data, 2009-2012 BIOLOGICAL ASPECTS RELEVANT TO FERBAM Ferbam is a dithiocarbamates fungicide (FRAC Code M3) of Fungicide Resistance Action Committee (FRAC , 2015). It 

### has multi-site contact activity against fungi. It 

### has low risk of developing resistance in fungi (FRAC, 2015). Ferbam is used for controlling fungal diseases on registered crops. It is mainly used on grapefruits and oranges to control scab disease. Ferbam can be used as a standalone fungicide or in combination/alternation with fungicides with different mode of action (such as azoxystrob in , pyraclostrobin, copper-based fungicides). Since 2004 , ferbam use has declined and this may be due to the re gistratio n of new fungicides (such as azoxystrobin, pyraclostrobin , trifloxystrobin) that are significantly more effective than ferbam in controlling the disease. ROLE OF FERBAM IN PEST MANAGEMENT Ferbam is predominantl y used on grapefruits and oranges in Florida. Grapefruit and oranges are g rown in California and Texas but they are no t treated with ferbam. Ferbam alone has been reported to be moderate ly effective against sca b di sease on citrus ( Dewdney, 2014) in 

### Florida. It is used in combination with azoxystrobin , pyraclostrobin and trifloxystrobin for sign ificantly better efficacy in controlling the disease and resistance management (Dewdney , 2014). Ferbam is registered for use on mangoes in Florida as special local need to control anthracnose disease.

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### DATA NEEDS Agricultural Use: 1. Propriety data show that ferbam use rate is higher than the labeled rate on citrus crops. Registrant may have information if this is true and what are the possible reasons? 2. Ferbam use and usage information on mangoes and cranberries. 

### REFERENCES Dewdney, MM. 2014. Quick reference guide to foliar fungicides. http : //www.crec.ifas
. ufl.edu/ extension/black spot/PDF /PP27500
.pdf
. Accessed on July l , 2015 FRAC. 2015. http ://www.frac.info/docs/default-source/publications/ frac-code-list/frac-code-list2015-finalC2AD7AA36764.pdf?sfvrsn=4 Accessed on June 20, 2015. Proprietary Data, 2004-2012.

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