FINAL – FEBRUARY 25, 2008

Page 1 of 3 

MEETING OF THE ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES (ACIP) 

Centers for Disease Control and Prevention 

1600 Clifton Road, NE, Tom Harkin Global Communications Center (Building 19), Atlanta, Georgia 

February 27-28, 2008 

AGENDA ITEM PURPOSE PRESIDER/PRESENTER(s)

Wednesday February 27

8:00 Welcome & Introductions

 

 Dr. Dale Morse (Chair, ACIP) 

Dr. Larry Pickering (Executive 

Secretary, ACIP; CDC) 

8:30 Influenza Vaccines

• Surveillance update 

• Vaccine strain selection and antiviral resistance 

• Vaccine effectiveness among 6-23 month old children 

• 2008 vaccination recommendations 

Information 

Information 

Discussion 

Information 

Discussion 

Information 

Discussion 

Vote 

VFC Vote 

Dr. Anthony Fiore (CDC/NCIRD/ID) 

Dr. Alexander Klimov 

(CDC/NCIRD/ID) 

Dr. David Shay (CDC/NCIRD/ID) 

Dr. Anthony Fiore (CDC/NCIRD/ID) 

Dr. Kathleen Neuzil (ACIP, WG 

Chair) 

Dr. Gregory Wallace 

(CDC/NCIRD/ISD) 

10:00 Break 

10:30 Meningococcal Conjugate Vaccine (MCV4) 

• Overview of session and Working Group update 

• Burden of meningococcal disease among infants and 

children 

• Recommendations for use of MCV4 among 2-10 year 

old children 

Information 

Information 

Discussion 

Vote 

Dr. Carol Baker (ACIP, WG Chair) 

Dr. Amanda Cohn (CDC/NCIRD/DBD) 

Dr. Ismael Ortega-Sanchez 

(CDC/NCIRD/DVD) 

Dr. Amanda Cohn (CDC/NCIRD/DBD) 

12:00 Lunch 

1:00 Use of Vaccines during Pregnancy & Breastfeeding

• Update on the activities of the ACIP Working Group on 

Vaccination during Pregnancy and Breastfeeding 

• Draft guiding principles for standardization of ACIP 

recommendations regarding vaccination during 

pregnancy and breastfeeding 

Information 

Information 

Discussion 

Dr. Carol Baker (ACIP, WG Chair) 

Dr. Stephanie Schrag 

(CDC/NCIRD/DBD) 

Dr. Carol Baker (ACIP, WG Chair) 

1:30 Human Papillomavirus (HPV) Vaccines

• Overview of session and Working Group update 

• Update on bivalent HPV vaccine 

• Quadrivalent HPV vaccine: end-of-study results and 

adult women 

• Epidemiology of HPV infection in older women 

• Cost effectiveness studies 

• Considerations for vaccination recommendations 

among women >26 years of age 

Information 

Information 

Information 

Information 

Information 

Information 

Discussion 

Dr. Janet Englund (ACIP, WG Chair) 

Dr. Gary Dubin (GSK) 

Dr. Richard Haupt (Merck) 

Dr. Eileen Dunne 

(CDC/NCHHSTP/DSTDP) 

Dr. Harrell Chesson 

(CDC/NCHHSTP/DSTDP) 

Dr. Lauri Markowitz 

(CDC/NCHHSTP/DSTDP) 

3:00 Break 
FINAL – FEBRUARY 25, 2008

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February 27 - continued 

3:30 Vaccine Safety Updates

• Introduction 

• Overview of VSD rapid cycle analysis (RCA) 

• RCA results for Measles Mumps Rubella Varicella 

(MMRV) Vaccine (ProQuad®) 

• Phase IV results for MMRV Vaccine 

• Summary and vote 

Information 

Information 

Information 

Information 

Discussion 

Information 

Vote 

Dr. John Iskander (CDC/OD/ISO) 

Dr. Tracy Lieu (ACIP, Harvard 

Pilgrim Health Care) 

Dr. Nicola Klein (Northern California 

Kaiser Permanente) 

Dr. Patricia Saddier (Epidemiology 

Group, Merck) 

Dr. Mona Marin (CDC/NCIRD/DVD) 

4:45 Vaccine Supply Information 

Discussion 

Dr. Greg Wallace (CDC/NCIRD/ISD) 

 

 

 

 

5:15 Public Comment 

5:30 Adjourn 

Thursday February 28

8:00 Unfinished Business Dr. Dale Morse (Chair, ACIP) 

8:20 Measles Outbreak – San Diego, CA, Jan-Feb 2008 Information 

Discussion 

Dr. Jane Seward (CDC/NCIRD/DVD) 

8:30 Agency Updates (CDC/CCID/NCIRD, CMS, DOD, DVA, 

FDA, HRSA, IHS, NIH, NVPO) 

Information 

8:45 Rotavirus Vaccines

• Update from Rotavirus Vaccines Working Group 

• Working Group considerations and draft of proposed 

recommendations 

• Adoption of rotavirus vaccine by pediatric and family 

medicine physicians 

Information 

Information

Discussion 

Information 

Dr. Lance Chilton (ACIP, WG Chair) 

Dr. Margaret Cortese 

(CDC/NCIRD/DVD) 

Ms. Shannan Stokley 

(CDC/NCIRD/ISD) 

9:45 Update: Implementation of Approach to Economic 

Analyses

Information Dr. Tracy Lieu (ACIP Member, 

member of ACIP Ad Hoc Working 

Group on Economic Analyses) 

9:50 Rabies Vaccines and Biologicals

• Update on supply of rabies vaccines and biologicals 

Information 

Discussion 

Dr. Charles Rupprecht 

(CDC/NCZVED/DVRD) 

10:10 Update: General Recommendations Information 

Discussion 

Dr. Ciro Sumaya (ACIP, WG Chair) 

Dr. Andrew Kroger (CDC/NCIRD/ 

ISD) 

10:30 Break

10:45 Japanese Encephalitis Vaccines

• Update from Japanese Encephalitis (JE) Vaccines 

Working Group 

• JE vaccine for U.S. travelers 

• JE vaccine availability in the U.S. 

• A new inactivated cell culture-derived JE vaccine for 

adult travelers 

• Questions and discussion 

Information 

Information 

Information 

Information 

Discussion 

Dr. Patsy Stinchfield (ACIP, WG 

Chair) 

Dr. Marc Fischer 

(CDC/NCZVED/DVBID) 

Mr. Phil Hosbach (sanofi pasteur) 

Dr. Erich Tauber (Intercell) 
FINAL – FEBRUARY 25, 2008

Page 3 of 3 

February 28 - continued 

11:45 Anthrax Vaccines

• Introduction 

• Background information on anthrax vaccine 

• Anthrax Vaccine Adsorbed: Overview of Safety Studies 

• Presentation of data on anthrax vaccine from the 

Anthrax Vaccine Research Program’s ongoing clinical 

trial 

Information 

Information 

Information 

Information 

Discussion 

Dr. Dale Morse (ACIP, WG Chair) 

Dr. Jennifer Wright 

(CDC/NCIRD/DBD) 

COL. Ted Cieslak (Department of 

Defense 

Dr. Jennifer Wright and Dr. Conrad 

Quinn (CDC/NCIRD/DBD) 

1:10 Public Comment 

1:30 Adjourn 

Acronyms 

ACIP Advisory Committee on Immunization Practices 

CCID Coordinating Center for Infectious Diseases 

CDC Centers for Disease Control & Prevention 

CMS Centers for Medicare and Medicaid Services 

DBD Division of Bacterial Diseases [of NCIRD] 

DOD Department of Defense 

DSTDP Division of Sexually Transmitted Diseases Prevention [of NCHHSTP] 

DVA Department of Veterans Affairs 

DVBID Division of Vector-Borne Infectious Diseases 

DVD Division of Viral Diseases [of NCIRD] 

DVH Division of Viral Hepatitis [of NCHHSTP] 

DVRD Division of Viral and Rickettsial Diseases 

FDA Food and Drug Administration 

HRSA Health Resources and Services Administration 

ID Influenza Division [of NCIRD] 

IHS Indian Health Service 

ISD Immunization Services Division [of NCIRD] 

ISO Immunization Safety Office (of CDC/OD/Office of the Chief Science Officer) 

NCHHSTP National Center for HIV, Hepatitis, STD and TB Prevention [of CDC/CCID] 

NCIRD CDC National Center for Immunization & Respiratory Diseases [of CDC/CCID] 

NCPDCID National Center for Preparedness, Detection, and Control of Infectious Diseases 

NCZVED National Center for Zoonotic, Vector-Borne, and Enteric Diseases [of CDC/CCID] 

NIH National Institutes of Health 

NVAC National Vaccine Advisory Committee 

NVPO National Vaccine Program Office 

OD Office of the Director [of CDC] 

TBD to be determined 

VSD Vaccine Safety Datalink 

WG Working Group
This document can be found on the CDC website at: 

http://www.cdc.gov/vaccines/recs/acip/downloads/agenda-feb08.pdf