FINAL – October 26, 2010

1 

MEETING OF THE ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES (ACIP)

Centers for Disease Control and Prevention

1600 Clifton Road, NE, Tom Harkin Global Communications Center (Building 19), Atlanta, Georgia

October 27-28, 2010

AGENDA ITEM PURPOSE PRESIDER/PRESENTER(s)

Wednesday, October 27, 2010

8:00

 

Welcome & Introductions

 

Dr. Carol Baker (Chair, ACIP)

Dr. Larry Pickering 

 (Executive Secretary, ACIP; CDC) 

8:30 Meningococcal Vaccine

 Introduction

 Considerations for people at high risk for 

meningococcal disease to receive 2-dose 1° series

 Cost-effectiveness of adolescent meningococcal 

vaccination

 Provider attitudes & practices regarding adolescent 

meningococcal vaccination

 Considerations regarding adolescent meningococcal 

vaccination

Information

Discussion

Vote

Information

& 

Discussion

Vote

VFC vote

Dr. Cody Meissner (ACIP, WG Chair)

Dr. Amanda Cohn (CDC/NCIRD)

Dr. Ismael Ortega-Sanchez 

(CDC/NCIRD)

Dr. Allison Kempe (University of 

Colorado)

Dr. Amanda Cohn (CDC/NCIRD)

Dr. Lance Rodewald (CDC/NCIRD)

10:00 Break

10:30 Hepatitis B Vaccine

 HepB vaccine coverage in high risk adults

 Work Group introduction

 Infection control initiatives

 Review of hepatitis B in adults with diabetes 

 Policy considerations – HepB vaccination for adults 

with diabetes

Information

& 

Discussion

Dr. Kathy Byrd (CDC/NCHHSTP)

Dr. Mark Sawyer (ACIP, WG Chair)

Dr. Joseph Perz (CDC/NCEZID) 

Dr. Trudy Murphy (CDC/NCHHSTP)

Dr. Trudy Murphy (CDC/NCHHSTP)

12:30 Lunch

1:30 Pertussis Vaccines

 Update on Pertussis Vaccines Work Group activities

 Update on pertussis outbreak – California, 2010 

 Proposed recommendation for use of Tdap regardless 

of Td interval

 Safety and immunogenicity of Tdap in people ≥65 

years of age

 Proposed recommendation for use of Tdap in people

≥65 years of age

 Proposed recommendation for use of Tdap in 

undervaccinated children 7-10 years of age

Information

& 

Discussion

Vote

Information

& 

Discussion

Vote

Vote

VFC votes

Dr. Mark Sawyer (ACIP, WG Chair)

Dr. Kathleen Harriman (CA Dept of 

Public Health)

Dr. Jennifer Liang (CDC/NCIRD)

Dr. Michael Decker – sanofi pasteur

Dr. Wayde Weston - GSK

Dr. Jennifer Liang (CDC/NCIRD)

Dr. Jennifer Liang (CDC/NCIRD)

Dr. Lance Rodewald (CDC/NCIRD)

3:45 Break

4:00 Evidence Based Recommendations

 Introduction

 Evidence-based format for ACIP recommendations: 

based on GRADE (Grades of Recommendation 

Assessment, Development, and Evaluation)

Information

&

Discussion

Vote

Dr. Jon Temte (ACIP, WG Chair)

Dr. Faruque Ahmed (CDC/NCIRD)

5:15 Public Comment 

5:30 Adjourn 
FINAL – October 26, 2010

2 

Thursday, October 28, 2010

8:00 Unfinished Business

 Update: Herpes Zoster (Shingles) Work Group Information

Dr. Carol Baker (Chair, ACIP)

Dr. Paul Cieslak (ACIP, WG Chair)

8:15 Agency Updates (CDC, CMS, DOD, DVA, FDA, HRSA, IHS, 

NIH, NVAC, NVPO)

Information ACIP Ex Officio Members

8:30 Human Papillomavirus (HPV) Vaccines

 Introduction

 HPV vaccine safety – Vaccine Safety Datalink

 HPV vaccine uptake in females and program issues

 HPV4 in males: clinical trial data

 Provider attitudes and practices regarding HPV vaccine 

use in males

 Review of cost effectiveness of male HPV vaccination

 Considerations for HPV vaccination recommendations 

in males

Information

& 

Discussion

Dr. Janet Englund (ACIP Member)

Ms. Julianne Gee (CDC/NCEZID)

Ms. Shannon Stokley (CDC/NCIRD)

Dr. Richard Haupt (Merck)

Dr. Mandy Allison (University of 

Colorado)

Dr. Harrell Chesson (CDC/NCHHSTP)

Dr. Lauri Markowitz 

(CDC/NCHHSTP)

10:20 Vaccine Supply Information Dr. Lance Rodewald (CDC/NCIRD)

10:30 Break

11:00 2011 Immunization Schedule – 0-18 years of age Information

Vote

Dr. Cody Meissner (ACIP, WG Chair)

Dr. William Atkinson (CDC/NCIRD)

11:30 2011 Immunization Schedule – 19 years of age and 

older

Information

Vote

Ms. Kris Ehresmann (ACIP, WG 

Chair)

Dr. Abigail Shefer (CDC/NCIRD)

12:00 Lunch

1:00 Rotavirus Vaccines

 Introduction

 Intussusception following administration of rotavirus 

vaccine (RV): GSK study, Mexico

 Intussusception following administration of RV: PAHO 

study, Brazil and Mexico

 US data on intussusception following administration of 

rotavirus vaccine (RV)

 Update: intussusception data; porcine circovirus

 Australian data on intussusception following 

administration of RV

 US analysis: benefits and risks of RV 

Information

& 

Discussion

Dr. Lance Chilton (ACIP, WG Chair)

Dr. Romulo Colindres, Director, GSK 

Biologicals

Dr. Manish Patel (CDC/NCIRD)

Dr. James Baggs (CDC/NCEZID) 

Dr. Christopher Mast, Dr. Colette 

Ranucci (Merck) 

Dr. Julie Bines (University of 

Melbourne, Australia)

Dr. Margaret Cortese (CDC/NCIRD)

3:00 Influenza

 Introduction

 Influenza activity worldwide

 Influenza vaccine availability

 Influenza vaccine safety

 

Information

& 

Discussion

Dr. Wendy Keitel (ACIP, WG Chair)

Dr. Tim Uyeki (CDC/NCIRD)

Dr. Lance Rodewald (CDC/NCIRD)

Dr. Tom Shimabukuro (CDC/NCEZID) 

3:30 Public Comment

3:45 Adjourn

Acronyms

CMS Centers for Medicare and Medicaid Services NCHHSTP National Center for HIV, Hepatitis, STD and TB Prevention

DOD Department of Defense NCIRD National Center for Immunization & Respiratory Diseases

DVA Department of Veterans Affairs NIH National Institutes of Health

FDA Food and Drug Administration NVAC National Vaccine Advisory Committee

HRSA Health Resources and Services Administration NVPO National Vaccine Program Office

IHS Indian Health Service WG Work Group

NCEZID National Center for Emerging and Zoonotic Infectious 

Diseases

This document can be found on the CDC website at: http://www.cdc.gov/vaccines/recs/acip/downloads/agenda-oct10.pdf