FINAL– 

– OCTOBER23,2007
 

 

 

 

 

8:30 Influenza Vaccines 

•	 Overview of session and influenza vaccine update 

•	 Use of live attenuated influenza vaccine (LAIV) in 24-

59 month old children 

 

 

•	 

 

MEETING OF THE ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES (ACIP) 

Centers for Disease Control and Prevention 

1600 Clifton Road, NE, Tom Harkin Global Communications Center (Building 19), Atlanta, Georgia 

October 24-25, 2007
 

AGENDA ITEM	 PURPOSE PRESIDER/PRESENTER(s) 

Wednesday October 24 

8:00	 Welcome & Introductions Dr. Julie Gerberding (Director, CDC) 

Dr. Dale Morse (Chair, ACIP) 

Dr. Larry Pickering (Executive 

Secretary, ACIP; CDC) 

Information

Information

Discussion 

Vote 

VFC Vote 

Dr. Anthony Fiore (CDC/NCIRD/ID) 

Dr. Greg Wallace, CDC/NCIRD/ISD) 

• Summary of CDC-CSTE consultants meeting: Influenza 

vaccine recommendations for 5-18 year olds 

•	 Summary of ACIP Influenza Working Group discussions 

Information 

Information 

Discussion 

Dr. Anthony Fiore (CDC/NCIRD/ID) 

Dr. Kathleen Neuzil (ACIP, WG

Chair) 

Dr. Anthony Fiore (CDC/NCIRD/ID) 

Cost-effectiveness of Influenza Vaccination: Updated 

Estimates for Children Aged 2-4 Years 

Federal Interagency Working Group: Draft Guidance 

on Pandemic Vaccine Prioritization 

Information 

Discussion 

Information 

Discussion 

Dr. Lisa Prosser (Harvard Medical 

School) 

• Dr. Benjamin Schwartz (CDC/NVPO) 

11:00 Break 

11:30 Pediatric Use of Pneumococcal Vaccines 

• Use of pneumococcal conjugate vaccine (PCV7) in 24-

59 month old children who are incompletely 

vaccinated 

Information 

Discussion 

Vote

Dr. Julie Morita (ACIP, WG Chair) 

Dr. Pekka Nuorti (CDC/NCIRD/DBD)

12:30 Lunch 

1:30 Meningococcal Conjugate Vaccine (MCV4) 

Introduction 

Update: meningococcal vaccine safety 

Immunogenicity and safety of Menactra® (MCV4) in 2-

10 year old children 

Proposed recommendations for use of MCV4 in 2-10 

year old children at increased risk of meningococcal 

disease 

•	 Introduction 

Information 

Information 

Information 

Discussion 

Vote 

Dr. Carol Baker (ACIP, WG Chair) 

Dr. Thomas Clark (CDC/NCIRD/DBD) 

Dr. Greg Gilmet (sanofi pasteur) 

Dr. Amanda Cohn (CDC/NCIRD/DBD) 

•	 

•	 

•	 

VFC Vote 

Information

Discussion 

Information 

Discussion 

Vote 

Dr. Greg Wallace (CDC/NCIRD/ISD) 

Considerations for routine use of MCV4 in 2-10 year Dr. Amanda Cohn (CDC/NCIRD/DBD) 

old children 

3:15 Childhood and Adolescent Immunization Schedule Dr. Angela Calugar 

(CDC/NCIRD/ISD) 

3:45	 Break 

4:00 Combination Vaccines 

•	 Update: Combination Vaccines Working Group 

•	 Impact of combination vaccines 

•	 Immunogenicity and safety of KinrixTM (combination 

DTaP-IPV vaccine) in children 4-6 years of age 

Information 

Information 

Information 

Ms. Patsy Stinchfield (ACIP, WG 

Chair) 

Dr. Greg Wallace (CDC/NCIRD/ISD) 

Dr. Wayde M. Weston (GSK) 

Page 1 of 3 
FINAL– 

– OCTOBER23,2007
 

 

 

 

Thursday October 25 

8:00 Unfinished Business 

8:30 Human Papillomavirus (HPV) Vaccines 

• Introduction 

• Overview of HPV vaccine trial data 

• Quadrivalent HPV vaccine cross-protection 

• Bivalent HPV baccine ASO4 adjuvant system 

• Bivalent HPV vaccine clinical overview and safety 

review 

• Outcomes related to HPV 6/11: recurrent respiratory 

papillomatosis and genital warts 

• Issues for ACIP consideration 

 

 

 

1:00 Rotavirus Vaccines 

• Working Group update 

• GSK’s Human Rotavirus Vaccine Rotarix® 

• PRV (RotaTeq®) update 

• Coverage, adherence with age recommendations 

• Safety monitoring update 

Information 

Discussion 

2:30 Update: Hepatitis B 

• Hepatitis B vaccination of adults 

• Identification and public health management of 

persons chronically infected with hepatitis B virus 

Information Dr. Cindy Weinbaum 

(CDC/NCHHSTP/DVH) 

 

 

Wednesday October 24, continued 

5:00 Immunization Schedule for HIV-Infected Adults Information 

Discussion 

Vote 

Dr. Gina Mootrey (CDC/NCIRD/ISD) 

5:30 Vaccine Supply Information Dr. Greg Wallace (CDC/NCIRD/ISD) 

6:00 Public Comment 

6:15 Adjourn 

Dr. Dale Morse (Chair, ACIP) 

Information 

Discussion Dr. Janet Englund (ACIP, WG Chair) 

Dr. Lauri Markowitz 

(CDC/NCHHSTP/ DSTDP) 

Dr. Richard Haupt (Merck) 

Dr. Martine Wettendorff (GSK) 

Dr. Gary Dubin (GSK) 

Dr. Elizabeth Unger (CDC/NCZVED) 

Dr. Eileen Dunne (CDC/NCHHSTP/ 

DSTDP) 

Dr. Lauri Markowitz 

(CDC/NCHHSTP/ DSTDP) 

10:45 Break 

11:00 Immunization Safety 

• Introduction 

• Early Thimerosal Exposure and Neuropsychological 

Outcomes at 7-10 Years 

• Summary of syncope reports to the Vaccine Adverse 

Events Reporting System (VAERS), Jan 2005-July 2007 

• Update: varicella vaccine safety 1995-2005 

Information 

Information 

Information 

Dr. John Iskander (CDC/OD/OCSO) 

Dr. Bill Thompson (CDC/NCIRD/ID) 

Dr. Barbara Slade (CDC/OD/OCSO) 

Dr. Sandra Chaves 

(CDC/NCIRD/DVD) 

12:00 Lunch 

Dr. Lance Chilton (ACIP, WG Chair) 

Dr. Leonard Friedman (GSK) 

Dr. Margaret Cortese 

CDC/NCIRD/DVD) 

Ms. Penina Haber (CDC/ISO/OSCO) 

3:00 Agency Updates (CDC/CCID/NCIRD, CMS, DOD, DVA, 

FDA, HRSA, IHS, NIH, NVPO) 

Information 

3:15 Public Comment 

3:30 Adjourn 

Page 2 of 3 
FINAL– 

– OCTOBER23,2007
 

Acronyms 

ACIP Advisory Committee on Immunization Practices 

CCID Coordinating Center for Infectious Diseases 

CDC Centers for Disease Control & Prevention 

CMS Centers for Medicare and Medicaid Services 

DBD Division of Bacterial Diseases [of NCIRD] 

DOD Department of Defense 

DSTDP Division of Sexually Transmitted Diseases Prevention [of NCHHSTP] 

DVA Department of Veterans Affairs 

DVD Division of Viral Diseases [of NCIRD] 

DVH Division of Viral Hepatitis [of NCHHSTP] 

FDA Food and Drug Administration 

HRSA Health Resources and Services Administration 

ID Influenza Division [of NCIRD] 

IHS Indian Health Service

ISD Immunization Services Division [of NCIRD] 

ISO Immunization Safety Office (of CDC/OD/Office of the Chief Science Officer) 

NCHHSTP National Center for HIV, Hepatitis, STD and TB Prevention [of CDC/CCID] 

NCIRD CDC National Center for Immunization & Respiratory Diseases [of CDC/CCID] 

NCPDCID National Center for Preparedness, Detection, and Control of Infectious Diseases

NCZVED National Center for Zoonotic, Vector-Borne, and Enteric Diseases [of CDC/CCID] 

NIH National Institutes of Health 

NVAC National Vaccine Advisory Committee 

NVPO National Vaccine Program Office 

OCSO Office of the Chief Science Officer [of OD] 

OD Office of the Director [of CDC] 

TBD to be determined 

WG Work Group 

Page 3 of 3 
 

 

This document can be found on the CDC website at: 

http://www.cdc.gov/vaccines/recs/acip/downloads/agenda-oct07.pdf