EX-10.10



 Exhibit 10.10 

ATARA BIOTHERAPEUTICS, INC. 

EMPLOYMENT AGREEMENT 

This Employment Agreement (the “Agreement”) is made and entered into as of March 31, 2014, by and between Atara
Biotherapeutics. Inc., a Delaware corporation (the “Company”) and Isaac Ciechanover, M.D. (“Executive”). From and following the date hereof, this Agreement shall replace and supersede that certain letter agreement
between the. Company and Executive dated September 6, 2012, as amended on October 22, 2012, and as further amended on December 5, 2012 (the “Prior Agreement”). 

RECITALS 

WHEREAS, the Company and Executive are currently parties to the Prior Agreement and wish to enter into
this Agreement as set forth herein in connection with a share exchange, pursuant to which each of Nina Biotherapeutics, Inc., Pinta Biotherapeutics, Inc. and Santa Maria Biotherapeutics, Inc. (each a “Project Entity”) shall become
wholly-owned subsidiaries of the Company (the “Share Exchange”); 
 NOW
THEREFORE, in consideration of the mutual promises and covenants contained herein and certain other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged. the parties agree as
follows: 
 AGREEMENT 

1. Duties and Scope of Employment. Executive will remain employed as the Company’s Chief Executive Officer,
reporting to the Company’s Board of Directors. This is a full-time position. While Executive renders services to the Company, Executive will not engage in any other employment, consulting or other business activity (whether full-time or
part-time) that would create a conflict of interest with the Company. By signing this Agreement, Executive reaffirms to the Company that Executive has no contractual commitments or other legal obligations that would prohibit Executive from
performing his duties for the Company. Subject to the approval of the Company’s Board of Directors (the “Board”) (which approval shall not be unreasonably withheld), Executive may elect to serve as a member of the board of
directors of other entities during Executive’s employment with the Company, provided, that such service does not interfere with the performance of Executive’s duties for the Company or create a conflict of interest with the Company.

 2. Cash Compensation. The Company will pay Executive a base salary at a rate of $381,100 per year (the
“Base Salary”), payable in accordance with the Company’s standard payroll schedule. This salary will be subject to upward adjustment pursuant to the. Company’s employee compensation policies in effect from time to time
Executive will also be entitled to a payment at the beginning of each month in an amount equal to $4,800 (the “Monthly Bonus”), which amount may be adjusted (as Executive and the Company may agree) as additional information is
obtained and can be used by Executive to cover certain additional expenses. in addition, Executive will be eligible to be considered for an incentive bonus for each fiscal year of the Company. Executive’s target bonus will be equal to 35% of
the Base Salary, and the applicable annual milestones for each fiscal year will be established mutually by Executive and the Company’s Board of Directors within 45 days following the start of the fiscal year Any bonus earned for a fiscal year
will be paid within 2 1/2 months after the close of that fiscal year. The determinations of the Company’s Board of Directors with respect to Executive’s bonus will be final and binding. 

  
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 3. Employee Benefits. The Company’s payroll and other human resource
management services will continue to be provided through TriNet Employer Group, Inc. (“TriNet”), a professional employer organization. As a result of the Company’s arrangement with TriNet, TriNet will be considered
Executive’s “employer of record” for these purposes. In addition, Executive will be entitled to paid time off in accordance with the Company’s paid time off policy, as in effect from time to time. 

4. Equity Compensation. 

(a) Prior Awards. Executive currently holds 1,386,000 shares of the Company’s common stock (post Share Exchange), which
were issued pursuant to the terms of certain Stock Purchase Agreements originally entered into between Executive and each Project Entity (each, a “Share Award”). Executive currently holds restricted stock units
(“RSUs,” and collectively with the Share Awards, the “Prior Awards”) covering 122,881 shares of the Company’s common stock (post Share Exchange). These equity awards will continue to be governed by the terms of
the applicable equity plans and award agreements. 
 (b) Single Trigger Acceleration. If the Company is subject to a Change in
Control before Executive’s service to the Company terminates, there will be 100% acceleration of all then-unvested equity awards Executive holds. In addition, the Prior Awards will continue to be eligible to receive the Project Entity-specific
accelerated vesting provided for in the original award agreement evidencing the Prior Award in connection with a Project Entity Change in Control. For example, if the Company elects to sell Nina Biotherapeutics, Inc. in a transaction that qualifies
as a Project Entity Change in Control, the Prior Awards which had originally been issued to Executive by Nina Biotherapeutics, Inc. shall be entitled to 100% acceleration in connection such transaction. 

(c) Bonus. The Company or the Project Entity which issued the applicable Share Award will pay to Executive or on
Executive’s behalf a bonus equal, on an after-tax basis, to the aggregate amount of withholding Executive incurs with respect to U.S, federal and state income and payroll taxes, as determined by the Company or such Project Entity in its sole
discretion, and will pay Executive an additional bonus amount to partially offset the tax liability Executive will incur from the payment to Executive or payment of such taxes on Executive’s behalf. 

5. Severance Benefits. 

(a) General. If Executive is subject to a Termination Without Cause, then Executive will be entitled to the benefits described
in this Section 5. However, this Section 5 will not apply unless Executive (i) has returned all Company property in Executive’s possession, (ii) has resigned as a member of the Boards of Directors of the Company and all of
its subsidiaries, to the extent applicable, (iii) has executed a general release of all claims that Executive may have against the Company or persons affiliated with the Company and (iv) if so requested, has executed a general release of
claims that Executive may have against the 

  
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Company. The releases must be in the form prescribed by the Company, without alterations. Executive must execute and return the releases on or before the dates specified in each prescribed form
(the “Release Deadline”). The Release Deadline will in no event be later than 50 days after Executive’s Separation. If Executive fails to return the releases on or before the Release Deadline, or if Executive revokes the
releases, then Executive will not be entitled to the benefits described in this Section 5. 
 (b) Cash Severance on Termination
Without Cause. If Executive is subject to a Termination Without Cause, then the Company will pay Executive a lump-sum severance payment equal to (i) six months’ Base Salary, at Executive’s final Base Salary rate; plus
(ii) an amount equal to six times the Monthly Bonus; plus (iii) if the Company makes bonus payments to other Company employees for (or during) the calendar/fiscal year in which Executive is subject to a Termination Without Cause, then and
only in this situation, the Company will pay Executive an amount equal to Executive’s full target bonus for the calendar/fiscal year in which Executive’s Separation occurs, which amount shall be prorated based upon the portion of that year
that Executive is employed by the Company. Such amount will be paid to Executive in accordance with the Company’s standard payroll procedures within 60 days after Executive’s Separation. However, if the 60-day period described in the
preceding sentence spans two calendar years, then the payment will in any event be made in the second calendar year. 
 (c) Additional
Payment in Lieu of Health Benefit. If Executive is subject to a Termination Without Cause, the Company will pay Executive an additional lump-sum amount equal to the product of (x) the monthly amount the Company was paying on behalf of
Executive and Executive’s eligible dependents with respect to the Company’s health insurance plans in which Executive and Executive’s eligible dependents were participants as of the day of Executive’s Separation multiplied by
(y) six. Such payment will be made in accordance with the Company’s standard payroll procedures and subject to the Company’s having first received effective releases pursuant to Section 5(a) above, will be paid within 60 days
after Executive’s Separation. However, if the 60-day period described in the preceding sentence spans two calendar years, then the payment will in any event be made in the second calendar year. 

(d) Accelerated Vesting. if Executive is subject to a Termination Without Cause, then the vested percentage of the Time-Based
Shares subject to each equity award will be determined by adding six months to the actual period of service that Executive has completed with the Company. 

(e) Section 409A. For purposes of Section 409A of the Code, each payment under Section 5 is hereby designated as
a separate payment. If the Company determines that Executive is a “specified employee” under Section 409A(a)(2)(B)(i) of the Code at the time of Executive’s Separation, then the payments under Section 5, to the extent that
they are subject to Section 409A of the Code, will be made on the first business day following (A) expiration of the six-month period measured from Executive’s Separation or (B) the date of Executive’s death. 

6. Proprietary Information and Inventions Agreement. Executive previously signed standard Proprietary Information and
Inventions Agreements with the Company and each Entity dated as of November 13, 2012 (collectively the “PHA”), which remain in full force and effect pursuant to its terms. 

  
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 7. Employment Relationship. Employment with the Company is for no specific
period of time. Executive’s employment with the Company is “at will,” meaning that either Executive or the Company may terminate Executive’s employment at any time and for any reason, with or without cause. Any contrary
representations that may have been made to Executive is superseded by this Employment Agreement. This is the full and complete agreement between Executive and the Company on this term. Although Executive’s job duties, title, compensation and
benefits, as well as the Company’s personnel policies and procedures, may change from time to time, the “at will” nature of Executive’s employment may only be changed in an express written agreement signed by Executive and a duly
authorized officer of the Company (other than Executive). 
 8. Miscellaneous. All forms of compensation
referred to in this Employment Agreement are subject to reduction to reflect applicable withholding and payroll taxes and other deductions required by law. Executive is encouraged to obtain Executive’s own tax advice regarding Executive’s
compensation from the Company. Executive agrees that the Company does not have a duty to design its compensation policies in a manner that minimizes Executive’s tax liabilities, and Executive will not make any claim against the Company or its
Board of Directors related to tax liabilities arising from Executive’s compensation. 
 9. Interpretation,
Amendment and Enforcement. This Agreement, and any equity agreements referred to herein, supersede and replace the Prior Agreement and any other prior agreements, representations or understandings (whether written, oral, implied or
otherwise) between Executive and the Company and, together with the PHA, constitutes the complete agreement between Executive and the Company regarding the subject matter set forth herein. This Agreement may not be amended or modified, except by an
express written agreement signed by both Executive and a duly authorized officer of the Company. The terms of this Agreement and the resolution of any disputes as to the meaning, effect, performance or validity of this Agreement arising out of,
related to, or in any way connected with this Agreement, Executive’s employment with the Company or any other relationship between Executive and the Company (the “Disputes”) will be governed by California law, excluding laws
relating to conflicts or choice of law. Executive and the Company submit to the exclusive personal jurisdiction of the federal and state courts located in California in connection with any Dispute or any claim related to any Dispute. 

10. Definitions. The following terms have the meaning set forth below wherever they are used in this Agreement: 

“Cause” means (a) Executive’s unauthorized use or disclosure of the Company’s confidential information or
trade secrets, which use or disclosure causes material harm to the Company, (b) Executive’s material breach of any agreement between Executive and the Company, (c) Executive’s material failure to comply with the Company’s
written policies or rules, (d) Executive’s conviction of, or Executive’s plea of “guilty” or “no contest” to, a felony under the laws of the United States or any State, (e) Executive’s gross negligence or
willful misconduct in connection with the performance of Executive’s duties for the Company, which negligence or misconduct results in material harm to the Company, (f) Executive’s continuing failure to perform lawful and reasonable
assigned duties after receiving written notification of the failure from the Company and a reasonable opportunity to correct such failure following Executive’s receipt of that notice, or (g) Executive’s failure to cooperate in good
faith with a governmental or internal investigation of the Company or its directors, officers or employees, if the 

  
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Company has requested Executive’s cooperation. For purposes of clarity, Executive’s refusal to relocate to another location (including, without limitation, to Thousand Oaks, California)
at the Company’s request shall not constitute “Cause.” 
 “Change in Control” means, 

(i) the merger, consolidation, recapitalization, or reorganization of the Company, other than a merger, consolidation,
recapitalization or reorganization which would result in the voting securities of the Company outstanding immediately prior thereto continuing to represent (either by remaining outstanding or by being converted into voting securities of the
surviving entity) more than fifty percent (50%) of the total voting power represented by the voting securities of the Company or such surviving entity outstanding immediately after such merger, consolidation, recapitalization or reorganization;

 (ii) the sale or disposition by the Company’s stockholders of more than fifty percent (50%) of the total voting
securities of the Company; 
 (iii) a complete liquidation or dissolution of the Company; 

(iv) the sale or disposition by the Company of all or substantially all of its assets; or 

(v) the exclusive licensing to a third party of all or substantially all of the Company’s intellectual property. 

Notwithstanding the foregoing, the following transactions shall not constitute a Change in Control; (i) a transaction the sole purpose of
which is to change the state of the Company’s incorporation or to create a holding company that will be owned in substantially the same proportions by the persons who held the Company’s securities immediately before such transaction;
(ii) a transaction or series of related transactions involving the sale of securities by the Company primarily for financing purposes; (iii) a merger or consolidation involving the Company and one or more companies under common management
control with the Company; or (iv) an IPO. If the timing of payments provided under an RSU Award agreement is based on or triggered by a Change in Control then, to extent necessary to avoid violating Code Section 409A, a Change in Control
must also constitute a “change in control event” (as defined under Code Section 409A regulations and applicable guidance). 

“Code” means the Internal Revenue Code of 1986, as amended. 

“IPO’ means an initial public offering by the applicable Entity or the Company of its equity securities pursuant to an
effective registration statement filed with the SEC. 
 “Project Entity Change in Control” means, with respect to an
Entity: 
 (i) a merger, spin-off or similar transaction involving (directly or indirectly) a Project Entity and, immediately after the
consummation of such merger, spin-off or similar transaction, the stockholders of the Company immediately prior thereto do not own, directly or indirectly, either (A) outstanding voting securities representing more than 50% of the combined
outstanding voting power of the Project Entity in such transaction or (B) more than 50% of the 

  
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combined outstanding voting power of the parent of the Project Entity in such transaction, in each case in substantially the same proportions as their ownership of the outstanding voting
securities of the Company immediately prior to such transaction; 
 (ii) the sale or disposition by the Company of all or substantially all
of the assets of a Project Entity; or 
 (iii) the exclusive licensing to a third party of all or substantially all of the Project
Entity’s intellectual property. 
 Notwithstanding the foregoing, the following transactions shall not constitute a Change in Control:
(i) a transaction the sole purpose of which is to change the state of such Entity’s incorporation or to create a holding company that will be owned in substantially the same proportions by the persons who held the applicable Entity’s
securities immediately before such transaction; (ii) a transaction or series of related transactions involving the sale of securities by such Entity primarily for financing purposes; (iii) a merger or consolidation involving such Entity
and one or more companies under common management control with such Entity; or (iv) an IPO. If the timing of payments provided under an RSU Award agreement is based on or triggered by a Project Entity Change in Control then, to extent necessary
to avoid violating Code Section 409A, a Project Entity Change in Control must also constitute a “change in control event” (as defined under Code Section 409A regulations and applicable guidance). 

“Separation” means a “separation from service,” as defined in the regulations under Section 409A of the Code.

 “Termination Without Cause” means a Separation as a result of a termination of Executive’s employment by the
Company other than for Cause or due to Executive’s death or disability, provided that Executive is willing and able to continue performing services within the meaning of Treasury Regulation 1.409A-1(nX1). 

* * * * * 

  
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 IN WITNESS WHEREOF, the
parties have executed this Employment Agreement as of the date set forth above. 
  

			
	ATARA BIOTHERAPEUTICS,
	
	 /s/ John McGrath

	By:	 	John McGrath
	Title:	 	
	
	ISAAC CIECHANOVER, M.D.
	
	 /s/ Isaac Ciechanover, M.D.




  
 [Signature Page to
Employment Agreement]