Appendix B

Appendix B-1 

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Appendix B: Vaccines 

United States Vaccines.........................................................................................B-3 

Vaccine Excipient Table ........................................................................................B-7 

Latex in Vaccine Packaging ...................................................................................B-11 

Vaccine-Preventable Disease Terms in Multiple Languages ....................................................B-13 

Resources for Vaccines........................................................................................B-15 

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Appendix B_Web.indd 2 11/1/2021 10:27:00 AM

Appendix B-2 

Appendix B

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Appendix B-3 

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Appendix B_Web.indd 3 11/1/2021 10:27:00 AM United States Vaccine Names United States Vaccines Vaccine Trade Name Abbreviation Manufacturer Route Doses in Routine Series Approved Ages 

Adenovirus Adenovirus Type 4 & Type 7 N/A Teva Pharmaceutical Industries Ltd. Oral (2 Tablets) 1 17-50 years L

pf

Anthrax BioThrax® AVA Emergent BioSolutions IM 3 18-65 years C

a

Cholera VaxchoraTM† N/A Emergent BioSolutions Oral (Liquid) 1 18-64 years L

DTaP Daptacel® DTaP Sanofi IM 5 6 weeks-6 years I

InfanrixTM DTaP GlaxoSmithKline IM 5 6 weeks-6 years I

DT N/A (Generic) DT Sanofi IM 5 6 weeks-6 years I

wc

Haemophilus influenzae type b (Hib) ActHIB® Hib (PRP-T) Sanofi IM 4 2 months-5 years I

c

HiberixTM Hib (PRP-T) GlaxoSmithKline IM 4 6 weeks- 4 years I

c

PedvaxHIB® Hib (PRP-OMP) Merck IM 3 2-71 months I

(

Hepatitis A HavrixTM HepA GlaxoSmithKline IM 2 Pediatric: 12 months-18 years; Adult: ≥19 years I

Vaqta® HepA Merck IM 2 Pediatric: 12 months-18 years; Adult: ≥19 years I

Hepatitis B Engerix-BTM HepB GlaxoSmithKline IM 3 Pediatric: Birth-19 years Adult: ≥20 years R

Recombivax HB® HepB Merck IM 3 Pediatric: Birth-19 years Adult: ≥20 years R

Heplisav-B® HepB Dynavax Technologies IM 2 ≥18 years R

Herpes Zoster (Shingles) ShingrixTM RZV GlaxoSmithKline IM 2 ≥50 years R

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Appendix B-4 

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Appendix B_Web.indd 4 11/1/2021 10:27:00 AM Vaccine Trade Name Abbreviation Manufacturer Route Doses in Routine Series Approved Ages 

Human Papillomavirus (HPV) Gardasil® 9 9vHPV Merck IM 2 or 3 9-45 years Influenza* Afluria Quadrivalent® IIV4 Seqirus IM 1 or 2 ≥6 months 

Fluad® Quadrivalent aIIV4 Seqirus IM 1 ≥65 years 

FluarixTM Quadrivalent IIV4 GlaxoSmithKline IM 1 or 2 ≥6 months 

Flublok® Quadrivalent RIV4 Sanofi IM 1 ≥18 years 

Flucelvax® Quadrivalent ccIIV4 Seqirus IM 1 or 2 ≥2 years 

FluLavalTM Quadrivalent IIV4 GlaxoSmithKline IM 1 or 2 ≥6 months 

FluMist® Quadrivalent LAIV4 AstraZeneca Intranasal 1 or 2 2-49 years 

Fluzone® Quadrivalent IIV4 Sanofi IM 1 or 2 ≥6 months 

Fluzone® High-Dose Quadrivalent HD-IIV4 Sanofi IM 1 ≥65 years 

Japanese encephalitis Ixiaro® JE Valneva IM 2 ≥2 months Measles, Mumps, Rubella M-M-R® II MMR Merck SC 2 ≥12 months Meningococcal (serogroups A, C, W, and Y) Menactra® MenACWY-D Sanofi IM 2 9 months-55 years 

MenquadfiTM MenACWY-TT Sanofi IM 2 ≥2 years 

MenveoTM MenACWY-CRM GlaxoSmithKline IM 2 2 months-55 years 

Meningococcal (serogroup B) Trumenba® MenB-FHbp Pfizer IM 2 or 3 10-25 years 

BexseroTM MenB-4C GlaxoSmithKline IM 2 10-25 years 

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Appendix B-5 

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Appendix B_Web.indd 5 11/1/2021 10:27:00 AM Appendix B_Web.indd 5 11/1/2021 10:27:00 AM Vaccine Trade Name Abbreviation Manufacturer Route Doses in Routine Series Approved Ages 

Pneumococcal Pneumovax® 23 PPSV23 Merck IM or SC 1 ≥2 years I

Prevnar 13® PCV13 Pfizer IM 4 (pediatric) 1 (adult) Pediatric: ≥6 weeks Adult: >65 years I

c

Polio Ipol® IPV Sanofi IM or SC 4 ≥6 weeks IRabies Imovax® N/A Sanofi IM 2-3 (pre-exposure) 4 (post-exposure) All ages I

RabAvert® N/A Bavarian Nordic IM 2-3 (pre-exposure) 4 (post-exposure) All ages I

Rotavirus RotaTeq® RV5 Merck Oral (Liquid) 3 6-32 weeks L

RotarixTM RV1 GlaxoSmithKline Oral (Liquid) 2 6-24 weeks L

Tetanus, (reduced) Diphtheria Tenivac® Td Sanofi IM 1 (Every 10 years) ≥7 years I

TdVaxTM Td Massachusetts Biological Labs IM 1 (Every 10 years) ≥7 years I

Tetanus, (reduced) Diphtheria, (reduced) Pertussis BoostrixTM Tdap GlaxoSmithKline IM 1 ≥10 years I

Adacel® Tdap Sanofi IM 1 10-64 years I

Typhoid Typhim Vi® N/A Sanofi IM 1 ≥2 years I

Vivotif® N/A Emergent BioSolutions Oral (Capsules) 4 ≥6 years L

Varicella Varivax® VAR Merck SC 2 ≥12 months L

Smallpox (Vaccinia) ACAM2000® — Emergent BioSolutions Percutaneous 1 All ages LSmallpox and Monkeypox JYNNEOS® — Bavarian Nordic SC 2 ≥18 years LYellow Fever YF-Vax® YF Sanofi SC 1 ≥9 months L

The abbreviations on this table (Column 3) were standardized jointly by staf of the Centers for Disease Control and Prevention, Advisory Committee on Immunization Practices (

of the Morbidity and Mortality Weekly Report (MMWR), the editor of Epidemiology and Prevention of Vaccine-Preventable Diseases (the Pink Book), ACIP members, and liaison These abbreviations are intended to provide a uniform approach to vaccine references used in ACIP Recommendations and Policy Notes published in the MMWR, the Pink BookPediatrics Red Book, and in the U.S. immunization schedules for children, adolescents, and adults. In descriptions of combination vaccines, a hyphen (-) indicates products in whsupplied in their fnal (combined) form by the manufacturer; a slash ( / ) indicates products in which active components must be mixed by the user. “Doses in a Routine Series” (Column 6) refects doses administered to a healthy patient at the recommended ages. It does not necessarily refect schedules for patients with healtfactors, alternative schedules, catch-up schedules, or booster doses not part of an initial series. For some combination vaccines, this column represents the routine number of dnecessarily the total number of doses in a complete series for the components. (For example, Kinrix or Quadracel may be used for only 1 dose of multi-dose DTaP and IPV series

“Adj.” in the “Comments” column indicates that the vaccine contains an adjuvant. A hyphen in an age range means “through” (i.e., “6 weeks-6 years” means 6 weeks through 6 years [to the 7th birthday]). *All infuenza vaccines in this table are 2021-2022 northern hemisphere formulations. For the most current recommendations on infuenza, see: https://www.cdc.gov/vaccines/hcp/acip-recs/vacc-specifc/fu.html †May be limited in supply as manufacturer has temporarily stopped production 
Appendix B-6 

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Appendix B_Web.indd 6 11/1/2021 10:27:00 AM Appendix B_Web.indd 6 11/1/2021 10:27:00 AM United States Combination Vaccines Vaccine Trade Name Abbreviation Manufacturer Route Doses in Routine Series Approved Ages 

DTaP, Polio KinrixTM DTaP-IPV GlaxoSmithKline IM 1 4-6 years Ina

5th 

Quadracel® DTaP-IPV Sanofi IM 1 4-6 years Ina

5th 

DTaP, hepatitis B, Polio PediarixTM DTaP-HepB-IPV GlaxoSmithKline IM 3 6 weeks-6 years Ina

2, 4

DTaP, Polio, Haemophilus influenzae type b Pentacel® DTaP-IPV/Hib Sanofi IM 4 6 weeks-4 years 4 In

for 

DTaP, Polio, Haemophilus influenzae type b, hepatitis B VaxelisTM DTaP-IPV-Hib-HepB Sanofi IM 3 6 weeks-4 years Ina

2, 4

Hepatitis A, Hepatitis B TwinrixTM HepA-HepB GlaxoSmithKline IM 3 ≥18 years Ina

Ped

Measles, Mumps, Rubella, Varicella ProQuad® MMRV Merck SC 2 12 months- 12 years Liv

The abbreviations on this table (Column 3) were standardized jointly by staf of the Centers for Disease Control and Prevention, Advisory Committee on Immunization Practices (

of the Morbidity and Mortality Weekly Report (MMWR), the editor of Epidemiology and Prevention of Vaccine-Preventable Diseases (the Pink Book), ACIP members, and liaison These abbreviations are intended to provide a uniform approach to vaccine references used in ACIP Recommendations and Policy Notes published in the MMWR, the Pink BookPediatrics Red Book, and in the U.S. immunization schedules for children, adolescents, and adults. In descriptions of combination vaccines, a hyphen (-) indicates products in whsupplied in their fnal (combined) form by the manufacturer; a slash ( / ) indicates products in which active components must be mixed by the user. “Doses in a Routine Series” (Column 6) refects doses administered to a healthy patient at the recommended ages. It does not necessarily refect schedules for patients with healtfactors, alternative schedules, catch-up schedules, or booster doses not part of an initial series. For some combination vaccines, this column represents the routine number of dnecessarily the total number of doses in a complete series for the components. (For example, Kinrix or Quadracel may be used for only 1 dose of multi-dose DTaP and IPV series

“Adj.” in the “Comments” column indicates that the vaccine contains an adjuvant. A hyphen in an age range means “through” (i.e., “6 weeks-6 years” means 6 weeks through 6 years [to the 7th birthday]). November 2021 
Appendix B

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Vaccine Excipient Summary 

Excipients Included in U.S. Vaccines, by Vaccine 

In addition to weakened or killed disease antigens (such as weakened, killed, or parts of viruses or bacteria), 

vaccines contain very small amounts of other ingredients – excipients. 

Some excipients are added to a vaccine for a specific purpose. These include: 

y	Preservatives, to prevent contamination. For example, thimerosal. 

y	Adjuvants, to help stimulate a stronger immune response. For example, aluminum salts. 

y	Stabilizers, to keep the vaccine potent during transportation and storage. For example, sugars or gelatin. 

Others are residual trace amounts of materials that were used during the manufacturing process and removed. 

These can include: 

y	Cell culture materials, used to grow the vaccine antigens. For example, egg protein, various culture media. 

y	Inactivating ingredients, used to kill viruses or inactivate toxins. For example, formaldehyde. 

y	Antibiotics, used to prevent contamination by bacteria. For example, neomycin. 

The following table lists substances, other than active ingredients (i.e., antigens), shown in the manufacturers’ 

package insert (PI) as being contained in the final formulation of each vaccine. Substances used in the 

manufacture of a vaccine but not listed as contained in the final product (e.g., culture media) can be found 

in each PI, but are not shown on this table. Each PI, which can be found on the FDA’s website (see below) 

contains a description of that vaccine’s manufacturing process, including the amount and purpose of each 

substance. In most PIs, this information is found in Section 11: “Description.” Please refer to the PI for a complete 

list of ingredients or excipients. A table listing vaccine excipients and media by excipient is published by the 

Institute for Vaccine Safety at Johns Hopkins University, and can be found at http://www.vaccinesafety.edu/ 

components-Excipients.htm. 

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Appendix B-8 

Appendix B

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Vaccine Excipient Table 

Vaccine (Trade Name) Package 

Insert Date Contains(a) 

Adenovirus 10/2019 monosodium glutamate, sucrose, D-mannose, D-fructose, dextrose, human serum 

albumin, potassium phosphate, plasdone C, anhydrous lactose, microcrystalline 

cellulose, polacrilin potassium, magnesium stearate, cellulose acetate phthalate, 

alcohol, acetone, castor oil, FD&C Yellow #6 aluminum lake dye 

Anthrax (Biothrax) 11/2015 aluminum hydroxide, sodium chloride, benzethonium chloride, formaldehyde 

BCG (Tice) 02/2009 glycerin, asparagine, citric acid, potassium phosphate, magnesium sulfate, iron 

ammonium citrate, lactose 

Cholera (Vaxchora) 06/2016 ascorbic acid, hydrolyzed casein, sodium chloride, sucrose, dried lactose, sodium 

bicarbonate, sodium carbonate 

Dengue (Dengvaxia) 06/2019 sodium chloride, essential amino acids (including L-phenylalanine), non-essential 

amino acids, L-arginine hydrochloride, sucrose, D-trehalose dihydrate, D-sorbitol, 

trometamol, urea 

DT (Sanofi) 06/2018 aluminum phosphate, isotonic sodium chloride, formaldehyde 

DTaP (Daptacel) 01/2021(b) aluminum phosphate, formaldehyde, glutaraldehyde, 2-phenoxyethanol 

DTaP (Infanrix) 01/2021(b) formaldehyde, aluminum hydroxide, sodium chloride, polysorbate 80 (Tween 80) 

DTaP-IPV (Kinrix) 01/2021(b) formaldehyde, aluminum hydroxide, sodium chloride, polysorbate 80 (Tween 

80), neomycin sulfate, polymyxin B 

DTaP-IPV (Quadracel) 02/2021 formaldehyde, aluminum phosphate, 2-phenoxyethanol, polysorbate 80, 

glutaraldehyde, neomycin, polymyxin B sulfate, bovine serum albumin 

DTaP-HepB-IPV (Pediarix) 01/2021(b) formaldehyde, aluminum hydroxide, aluminum phosphate, sodium chloride, 

polysorbate 80 (Tween 80), neomycin sulfate, polymyxin B, yeast protein 

DTaP-IPV/Hib (Pentacel) 12/2019 aluminum phosphate, polysorbate 80, sucrose, formaldehyde, glutaraldehyde, 

bovine serum albumin, 2-phenoxyethanol, neomycin, polymyxin B sulfate 

DTaP-IPV-Hib-HepB (Vaxelis) 10/2020 polysorbate 80, formaldehyde, glutaraldehyde, bovine serum albumin, 

neomycin, streptomycin sulfate, polymyxin B sulfate, ammonium thiocyanate, 

yeast protein, aluminum 

Ebola Zaire (ERVEBO) 01/2021(b) Tromethamine, rice-derived recombinant human serum albumin, host cell DNA, 

benzonase, rice protein 

Hib (ActHIB) 05/2019 sodium chloride, formaldehyde, sucrose 

Hib (Hiberix) 04/2018 formaldehyde, sodium chloride, lactose 

Hib (PedvaxHIB) 01/2021(b) amorphous aluminum hydroxyphosphate sulfate, sodium chloride 

Hep A (Havrix) 01/2021(b) MRC-5 cellular proteins, formalin, aluminum hydroxide, amino acid supplement, 

phosphate-buffered saline solution, polysorbate 20, neomycin sulfate, 

aminoglycoside antibiotic 

Hep A (Vaqta) 01/2021(b) amorphous aluminum hydroxyphosphate sulfate, non-viral protein, DNA, bovine 

albumin, formaldehyde, neomycin, sodium borate, sodium chloride, other 

process chemical residuals 

Hep B (Engerix-B) 01/2021(b) aluminum hydroxide, yeast protein, sodium chloride, disodium phosphate 

dihydrate, sodium dihydrogen phosphate dihydrate 

Hep B (Recombivax) 12/2018 formaldehyde, potassium aluminum sulfate, amorphous aluminum 

hydroxyphosphate sulfate, yeast protein 

Hep B (Heplisav-B) 05/2020 yeast protein, yeast DNA, deoxycholate, phosphorothioate linked 

oligodeoxynucleotide, sodium phosphate, dibasic dodecahydrate, sodium 

chloride, monobasic dehydrate, polysorbate 80 

Hep A/Hep B (Twinrix) 01/2021(b) MRC-5 cellular proteins, formalin, aluminum phosphate, aluminum hydroxide, 

amino acids, sodium chloride, phosphate buffer, polysorbate 20, neomycin 

sulfate, yeast protein

 HPV (Gardasil 9) 08/2020 amorphous aluminum hydroxyphosphate sulfate, sodium chloride, 

L-histidine, polysorbate 80, sodium borate, yeast protein 

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Appendix B-9 

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Vaccine (Trade Name) Package 

Insert Date Contains(a) 

Influenza (Afluria) 

Quadrivalent(c) 

03/2021 sodium chloride, monobasic sodium phosphate, dibasic sodium phosphate, 

monobasic potassium phosphate, potassium chloride, calcium chloride, sodium 

taurodeoxycholate, ovalbumin, sucrose, neomycin sulfate, polymyxin B, betapropiolactone, hydrocortisone, thimerosal (multi-dose vials) 

Influenza (Fluad) 

Quadrivalent(c) 

03/2021 squalene, polysorbate 80, sorbitan trioleate, sodium citrate dihydrate, citric acid 

monohydrate, neomycin, kanamycin, hydrocortisone, egg protein, formaldehyde 

Influenza (Fluarix) 

Quadrivalent(c) 

2021 octoxynol-10 (TRITON X-100), α-tocopheryl hydrogen succinate, polysorbate 

80 (Tween 80), hydrocortisone, gentamicin sulfate, ovalbumin, formaldehyde, 

sodium deoxycholate, sodium phosphate-buffered isotonic sodium chloride 

Influenza (Flublok) 

Quadrivalent(c) 

03/2021 sodium chloride, monobasic sodium phosphate, dibasic sodium phosphate, 

polysorbate 20 (Tween 20), baculovirus and Spodoptera frugiperda cell proteins, 

baculovirus and cellular DNA, Triton X-100 

Influenza (Flucelvax) 

Quadrivalent(c) 

10/2021(b) Madin Darby Canine Kidney (MDCK) cell protein, phosphate buffered saline, 

protein other than HA, MDCK cell DNA, polysorbate 80, cetyltrimethlyammonium 

bromide, and β-propiolactone, thimerosal (multi-dose vials) 

Influenza (Flulaval) 

Quadrivalent(c) 

2021 ovalbumin, formaldehyde, sodium deoxycholate, α-tocopheryl hydrogen 

succinate, polysorbate 80, phosphate-buffered saline solution 

Influenza (Fluzone) 

Quadrivalent(c) 

2021 formaldehyde, egg protein, octylphenol ethoxylate (Triton X-100), sodium 

phosphate-buffered isotonic sodium chloride solution, thimerosal (multi-dose 

vials) 

Influenza (Fluzone) 

High Dose(c) 

07/2021 egg protein, octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered 

isotonic sodium chloride solution, formaldehyde 

Influenza (FluMist) 

Quadrivalent(c) 

08/2021 monosodium glutamate, hydrolyzed porcine gelatin, arginine, sucrose, dibasic 

potassium phosphate, monobasic potassium phosphate, ovalbumin, gentamicin 

sulfate, ethylenediaminetetraacetic acid (EDTA) 

IPV (Ipol) 01/2021(b) calf bovine serum albumin, 2-phenoxyethanol, formaldehyde, neomycin, 

streptomycin, polymyxin B, M-199 medium 

Japanese Encephalitis (Ixiaro) 09/2018 aluminum hydroxide, protamine sulfate, formaldehyde, bovine serum albumin, 

host cell DNA, sodium metabisulphite, host cell protein 

MenACWY (Menactra) 04/2018 sodium phosphate buffered isotonic sodium chloride solution, formaldehyde, 

diphtheria toxoid protein carrier 

MenACWY (MenQuadfi) 01/2021(b) sodium chloride, sodium acetate, formaldehyde 

MenACWY (Menveo) 07/2020 formaldehyde, CRM protein 197

MenB (Bexsero) 01/2021(b) aluminum hydroxide, sodium chloride, histidine, sucrose, kanamycin 

MenB (Trumenba) 2018 polysorbate 80, aluminum phosphate, histidine buffered saline 

MMR (MMR-II) 12/2020 sorbitol, sucrose, hydrolyzed gelatin, recombinant human albumin, neomycin, 

fetal bovine serum, WI-38 human diploid lung fibroblasts 

MMRV (ProQuad) 

(Frozen: Recombinant 

Albumin) 

01/2021(b) MRC-5 cells including DNA and protein, sucrose, hydrolyzed gelatin, sodium 

chloride, sorbitol, monosodium L-glutamate, sodium phosphate dibasic, 

recombinant human albumin, sodium bicarbonate, potassium phosphate 

monobasic, potassium chloride, potassium phosphate dibasic, neomycin, bovine 

calf serum, other buffer and media ingredients 

PCV13 (Prevnar 13) 08/2017 CRM carrier protein, polysorbate 80, succinate buffer, aluminum phosphate 197

PPSV-23 (Pneumovax) 09/2020 isotonic saline solution, phenol 

Rabies (Imovax) 10/2019 human albumin, neomycin sulfate, phenol red, beta-propiolactone 

Rabies (RabAvert) 2018 chicken protein, polygeline (processed bovine gelatin), human serum albumin, 

potassium glutamate, sodium EDTA, ovalbumin, neomycin, chlortetracycline, 

amphotericin B 

Rotavirus (RotaTeq) 01/2021(b) sucrose, sodium citrate, sodium phosphate monobasic monohydrate, sodium 

hydroxide, polysorbate 80, cell culture media, fetal bovine serum 

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Appendix B-10 

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Vaccine (Trade Name) Package 

Insert Date Contains(a) 

Rotavirus (Rotarix) 01/2021(b) dextran, Dulbecco’s Modified Eagle Medium (sodium chloride, potassium 

chloride, magnesium sulfate, ferric (III) nitrate, sodium phosphate, sodium 

pyruvate, D-glucose, concentrated vitamin solution, L-cystine, L-tyrosine, 

amino acids, L-glutamine, calcium chloride, sodium hydrogenocarbonate, and 

phenol red), sorbitol, sucrose, calcium carbonate, sterile water, xanthan 

[Porcine circovirus type 1 (PCV1) is present in Rotarix. PCV-1 is not known to 

cause disease in humans.] 

Smallpox 

(Vaccinia) (ACAM2000) 

03/2018 HEPES, 2% human serum albumin, 0.5 - 0.7% sodium chloride USP, 5% Mannitol 

USP, neomycin, polymyxin B, 50% Glycerin USP, 0.25% phenol USP 

Td (Tenivac) 11/2019 aluminum phosphate, formaldehyde, sodium chloride 

Td (TDVAX) 09/2018 aluminum phosphate, formaldehyde, thimerosal 

Tdap (Adacel) 12/2020 aluminum phosphate, formaldehyde, 2-phenoxyethanol, glutaraldehyde 

Tdap (Boostrix) 09/2020 formaldehyde, aluminum hydroxide, sodium chloride, polysorbate 80 

Typhoid (Typhim Vi) 03/2020 formaldehyde, phenol, polydimethylsiloxane, disodium phosphate, monosodium 

phosphate, sodium chloride 

Typhoid (Vivotif Ty21a) 9/2013 sucrose, ascorbic acid, amino acids, lactose, magnesium stearate, gelatin 

Varicella (Varivax) Frozen 01/2021(b) sucrose, hydrolyzed gelatin, sodium chloride, monosodium L-glutamate, sodium 

phosphate dibasic, potassium phosphate monobasic, potassium chloride, MRC-5 

human diploid cells including DNA & protein, sodium phosphate monobasic, 

EDTA, neomycin, fetal bovine serum 

Yellow Fever (YF-Vax) 2/2019 sorbitol, gelatin, sodium chloride 

Zoster (Shingles) (Shingrix) 01/2021(b) sucrose, sodium chloride, dioleoyl phosphatidylcholine (DOPC), 3-O-desacl4’monophosphoryl lipid A (MPL), QS-21 (a saponin purified from plant extract 

Quillaja saponaria Molina), potassium dihydrogen phosphate, cholesterol, 

sodium dihydrogen phosphate dihydrate, disodium phosphate anhydrous, 

dipotassium phosphate, polysorbate 80, host cell protein and DNA 

Abbreviations: DT = diphtheria and tetanus toxoids; DTaP = diphtheria and tetanus toxoids and acellular pertussis; Hep A = Hepatitis A; Hep B = Hepatitis B; Hib = 

Haemophilus infuenzae type b; HPV = human papillomavirus; IPV = inactivated poliovirus; LAIV = live, attenuated infuenza vaccine; MenACWY = quadrivalent 

meningococcal conjugate vaccine; MenB = serogroup B meningococcal vaccine; MMR = measles, mumps, and rubella; MMRV = measles, mumps, rubella, varicella; PCV13 

= pneumococcal conjugate vaccine; PPSV23= pneumococcal polysaccharide vaccine; Td = tetanus and diphtheria toxoids; Tdap = tetanus toxoid, reduced diphtheria 

toxoid, and acellular pertussis.

 (a)All information was extracted from manufacturers’ package inserts. The date shown in the Date column of the table is the edition date of the PI in use in January 2021 by 

month and year. In some cases, only a year was printed on the PI. If in doubt about whether a PI has been updated since this table was prepared, check the FDA’s website 

at: 

http://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm093833.htm 

(b)The PI was not dated and this is the date the PI was reviewed for this table. 

(c)All infuenza vaccine in this table are 2021-22 northern hemisphere formulation. November 2021 

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Latex in Vaccine Packaging 

“Immediate-type allergic reactions due to latex allergy have been described after vaccination, but such reactions 

are rare. If a person reports a severe anaphylactic allergy to latex, vaccines supplied in vials or syringes that 

contain natural rubber latex should be avoided if possible. If not, if the decision is made to vaccinate, providers 

should be prepared to treat immediate allergic reactions due to latex, including anaphylaxis. The most common 

type of latex hypersensitivity is a delayed-type (type 4, cell-mediated) allergic contact dermatitis. For patients with 

a history of contact allergy to latex, vaccines supplied in vials or syringes that contain dry natural rubber or natural 

rubber latex may be administered.” 

(ACIP General Best Practice Guidelines for Immunization) 

Vaccine (Trade Name) Package Insert Date Latex (Yes/No)(a) 

Adenovirus 10/2019 No 

Anthrax (Biothrax) 11/2015 Yes 

BCG (Tice) 02/2009 No 

Cholera (Vaxchora) 06/2016 No 

Dengue (Dengvaxia) 06/2019 No 

DT (Sanofi) 06/2018 No 

DTaP (Daptacel) 01/2021(b) No 

DTaP (Infanrix) 01/2021(b) Yes – Syringe, No – Vial 

DTaP-IPV (Kinrix) 01/2021(b) Yes – Syringe, No – Vial 

DTaP-IPV (Quadracel) 02/2021 No 

DTaP-HepB-IPV (Pediarix) 01/2021(b) Yes 

DTaP-IPV/Hib (Pentacel) 12/2019 No 

DTaP-IPV-Hib-HepB (Vaxelis) 10/2020 No 

Ebola Zaire (ERVEBO) 01/2021(b) No 

Hib (ActHIB) 05/2019 No 

Hib (Hiberix) 04/2018 No 

Hib (PedvaxHIB) 01/2021(b) Yes 

Hep A (Havrix) 01/2021(b) Yes – Syringe , No – Vial 

Hep A (Vaqta) 01/2021(b) Yes – Syringe, Yes – Vial 

Hep B (Engerix-B) 01/2021(b) Yes – Syringe, No – Vial 

Hep B (Recombivax) 12/2018 Yes – Syringe, Yes – Vial 

Hep B (Heplisav-B) 05/2020 No 

Hep A/Hep B (Twinrix) 01/2021(b) Yes 

HPV (Gardasil 9) 08/2020 No 

Influenza (Afluria) Quadrivalent(c) 03/2021 No 

Influenza (Fluad) Quadrivalent(c) 03/2021 No 

Influenza (Fluarix) Quadrivalent(c) 2021 No 

Influenza (Flublok) Quadrivalent(c) 03/2021 No 

Influenza (Flucelvax) Quadrivalent(c) 10/2021(b) No 

Influenza (Flulaval) Quadrivalent(c) 2021 No 

Influenza (Fluzone) Quadrivalent(c) 2021 No 

Influenza (Fluzone) High Dose(c) 2021 No 

Influenza (FluMist) Quadrivalent(c) 08/2021 No 

IPV (Ipol) 01/2021(b) No 

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Vaccine (Trade Name) Package Insert Date Latex (Yes/No)(a) 

Japanese Encephalitis (Ixiaro) 09/2018 No 

MenACWY (Menactra) 04/2018 No 

MenACWY(MenQuadfi) 01/2021(b) No 

MenACWY (Menveo) 07/2020 No 

MenB (Bexsero) 01/2021(b) Yes 

MenB (Trumenba) 2018 No 

MMR (M-M-R II) 12/2020 No 

MMRV (ProQuad) (Frozen: Recombinant Albumin) 01/2021(b) No 

PCV13 (Prevnar 13) 08/2017 No 

PPSV-23 (Pneumovax) 09/2020 No 

Rabies (Imovax) 10/2019 No 

Rabies (RabAvert) 2018 No 

Rotavirus (RotaTeq) 01/2021(b) No 

Rotavirus (Rotarix) 01/2021(b) Yes 

Smallpox (Vaccinia) (ACAM2000) 03/2018 No 

Td (Tenivac) 11/2019 Yes – Syringe, No – Vial 

Td (TDVAX) 09/2018 No 

Tdap (Adacel) 12/2020 Yes(d) – Syringe, No – Vial 

Tdap (Boostrix) 09/2020 Yes – Syringe, No – Vial 

Typhoid (Typhim Vi) 03/2020 No 

Typhoid (Vivotif Ty21a) 09/2013 No 

Varicella (Varivax) Frozen 01/2021(b) No 

Yellow Fever (YF-Vax) 02/2019 No 

Zoster (Shingles) (Shingrix) 01/2021(b) No 

Abbreviations: DT = diphtheria and tetanus toxoids; DTaP = diphtheria and tetanus toxoids and acellular pertussis; Hep A = Hepatitis A; Hep B = Hepatitis B; Hib 

= Haemophilus infuenzae type b; HPV = human papillomavirus; IPV = inactivated poliovirus; LAIV = live, attenuated infuenza vaccine; MenACWY = quadrivalent 

meningococcal conjugate vaccine; MenB = serogroup B meningococcal vaccine; MMR = measles, mumps, and rubella; MMRV = measles, mumps, rubella, varicella; 

PCV13 = pneumococcal conjugate vaccine; PI = Package Insert; PPSV23= pneumococcal polysaccharide vaccine; Td = tetanus and diphtheria toxoids; Tdap = tetanus 

toxoid, reduced diphtheria toxoid, and acellular pertussis.

 (a)All information was extracted from manufacturers’ package inserts. The date shown in the Date column of the table is the edition date of the PI is use in 

February 2020. If in doubt about whether a PI has been updated since this table was prepared, check the FDA’s website at: 

http://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm093833.htm 

(b)The PI was not dated and this is the date the PI was reviewed for this table. 

(c) All infuenza vaccine in this table are 2021-2022 northern hemisphere formulation. 

(d)The most current PI (12/2020) indicates no latex in any presentation of Adacel. Previous PIs indicate tip caps of some lots of Adacel preflled syringes contain latex 

while others do not. Check the package insert that came with your vaccine, if necessary. 

November 2021 

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Appendix B-13 

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Appendix B_Web.indd 13 11/1/2021 10:27:02 AM Quick Chart of Vaccine-Preventable Disease Terms in Multiple Languages 

Eastern European Languages English Bosnian Croatian Polish Romanian Russian Serbian Slovak 

DTP (DTaP) Detepe Detepe DTaP Di-Te-Per АКДС Detepe DiTePe Diphtheria Difterija Difterije Błonica Difteriei Дифтерия Дифтерије Diftéria; záškrt 

Haemophilus influenzae type b Hemofilična influenca tipa B Haemophilus influenzae tipa b Haemophilus influenzae typu b Haemophilus influenza tip b boala ΓемофИльноЯ инфекциЯ типа B Хаемопхилус инфлуензае тип Б болести Haemophilus influenza typ b; ochorenia 

Hepatitis A Žutica A, Hepatitis A Žutica A, hepatitisa A Wirusowe zapalenie wątroby typu A Hepatita A Γепатит А Xепатитиса A Hepatitída A 

Hepatitis B Žutica B, Hepatitis B Žutica B, hepatitisa B Wirusowe zapalenie wątroby typu B Hepatita B Γепатит B Xепатитиса B Hepatitída B Human papillomavirus Ljudski papiloma virus Papilomavirusi čovjeka Wirus brodawczaka ludzkiego Papilomavirus uman Вирус папилломы человека људски папилома вирус L’udský papillomavírus 

Influenza Gripa Gripe Grypa Gripa Γрипп грип Chrípka MMR MMR ΜMR Measles Rubeola Ospice Odra Pojarul КоpЬ Μале бοгиње Morbilli; Osýpky Meningococcal ACWY Meningokokal ACWY Meningokoknog ACWY Meningokoki ACWY Meningococice ACWY менингококковая ACWY Mенингококне ACWY Meningokokove ACWY Mumps Zauške ZauŠnjaci Świnka Oreionul, Oreion Cвинка, Паротит Эаушκе Priusnica 

Pertussis Veliki kašalj Kašalj hripavac Krztusiec Tusei convulsive Kоклюша ПеpТycИc Čierny kašeľ 

Poliomyelitis Dječja paraliza Dječje paralize Paraliż dziecięcy Poliomielita Пoлиомиелит ПoлизoМИеЛИТ Detská obrna 

Pneumococcal conjugate Upala pluča Pneumokoka konjugirano Pneumokoki Pneumococic conjugat Конъюгированная ᴨневмококковоя Пнеумоцоццал коњунговане Konjugovaná pneumokoková 

Rotavirus Rotavirus Rotawirus Rotawirus Rotavirus Pотавᴎрус PотавирусНа ИНФeКЦИja Ροтавирус 

Rubella Male boginje Rubeola Różyczka Pojar German Kраснуха Ρубеοла Rubeola 

Shingles (Herpes zoster) Herpes zoster Šindra Półpasiec Herpes zoster (zona zoster) OпоясЬывающий лишай Xерпес зостер (појасни херпес) Pásového oparu; Pásový opar Smallpox Veliki boginje Veliki boginje Ospa Variola, variolei Oспа Veliki boginje Kiahne Tetanus Tetanus Tetanusa Tężec Tetanosului столбняк Тетануса Tetanus 

Tuberculosis Tuberkuloza Tuberkuloza Gruźlica Tuberculozei Tуберкулёз Tuberkuloza Tuberkulóza 

Varicella (chickenpox) Ospice Vodene kozice Ospa wietrzna Varicelă Ветряная оспа (Ветряная) ВариЦелла (цхицкен богиње) Ovčím kiahňam; Ovčie kiahne 

Immunization action coalition Saint Paul, Minnesota • 651-647-9009 • www.immunize.org • www.vaccineinformation.orgwww.immunize.org/catg.d/p512

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Appendix B_Web.indd 14 11/1/2021 10:27:02 AM Quick Chart of Vaccine-Preventable Disease Terms in Multiple Languages 

Western European Languages English Dutch French German Italian Norwegian Portuguese Spanish 

DTP DKTP DT Coq, DTC Tríplice 

Diphtheria Difterie Diphtérie Diphtherie Difterite Difteri Difteria Difteria Haemophilus influenzae type b Haemophilus influenzae b Haemophilus influenzae de type b Haemophilus influenzae type b Haemophilus influenzae b Haemophilus influenzae tipe b Doenca Haemophilus influenzae tipo b Hemófilo tipo b

Haemophilus influenzae tipo 

Hepatitis A Hepatitis A Hepatite A Hepatitis A Epatite A Hepatitt A Hepatite A hepatitis A Hepatitis B Hepatitis B Hepatite B Hepatitis B Epatite B Hepatitt B Hepatite B hepatitis B 

Human papillomavirus Humaan papillovirus Papillovirus humaines Humanen papillovirus Il papillovirus umano Humant papillomavirus Virus do papiloma humano Virus del papilo

humano 

Influenza (“flu”) Griep Grippe Grippe L’nfluenzae Influensa Gripe Gripe MMR BMR ROR MMR MPR VASPR SRP Measles Mazelen Rougeole Masern Morbillo Meslinger Sarampo Sarampión, Sarampión comMeningococcal ACWY Meningokokken ACWY Antiméningo- coque ACWY Meningokokken ACWY Meningococcico ACWY Meningokokksyk- dom ACWY Meningocóccica ACWY Meningococo ACWY Mumps Bof Oreillons Ziegenpeter Parotite Kusma Caçhumba Paperas, Parotiditis 

Pertussis (Whooping cough) Kinkhoest Coqueluche Keuchhusten Pertosse (tosse asinina) Kikhoste Coqueluche Coqueluche (Tos ferina) 

Poliomyelitis Kinderverlamming Poliomyélite Kinderlähmung Poliomielite Poliomyelitt Poliomielite, paralisia Infantil Poliomielitis 

Pneumococcal conjugate Pneumokokken conjugaat Antipneumococ- cique conjugué Pneumokokken konjugat Pneumococcico coniugato Pneumokokk komjugatvaksine Pneumocócica conjugada Antineumocóc

conjugada 

Rotavirus Rotavirus Rotavirus Rotavirus Rotavirus Rotavirus Rotavírus Rotavirus 

Rubella Rode hond Rubéole Röteln Rosolia Røde hunder Rubéola (sarampo alamão) Rubéola, Sarampión ale

Shingles (Herpes zoster) Gordelroos (herpes zoster) Zona (l’herpès zoster) Gürtelrose (herpes zoster) Fuoco di Sant’Antonion (l’herpes zoster) Helvetesild (herpes zoster) Zona (herpes zoster) Zona de matoj

(herpes) 

Smallpox Pokken Variole Pocken Vaioloso Kopper Varíola Viruela 

Tetanus Stijfkramp Tétanos Wundstarrkrampf Tetano Stivkrampe Tétano, Tetânica Tétanos, Tetán

Tétano 

Tuberculosis Tering Tuberculose Tuberkulose Tubercolosi Tuberkulose Tuberculose Tuberculínica 

Varicella (chickenpox) Varicella (waterpekkea) Varicelle Varizellen (windpocken) Varicella Vannkopper Varicella (catapora) Varicela 

Immunization action coalition Saint Paul, Minnesota • 651-647-9009 • www.immunize.org • www.vaccineinformation.orgwww.immunize.org/catg

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Resources for Vaccines 

Vaccine Excipients 

y	Food and Drug Administration (FDA) Vaccine Package Inserts: https://www.fda.gov/vaccines-blood-biologics/ 

vaccines/vaccines-licensed-use-united-states 

y	Thimerosal and Vaccines (FDA): https://www.fda.gov/vaccines-blood-biologics/safety-availability-biologics/ 

thimerosal-and-vaccines 

y	Thimerosal and Vaccines (CDC): https://www.cdc.gov/vaccinesafety/concerns/thimerosal/index.html 

y	Common Ingredients in U.S. Licensed Vaccines (FDA): https://www.fda.gov/vaccines-blood-biologics/safetyavailability-biologics/common-ingredients-us-licensed-vaccines 

y	Excipients in Vaccines per 0.5 mL dose (Johns Hopkins): https://www.vaccinesafety.edu/components-Excipients.htm 

Interpreting Vaccines from Other Countries 

y	World Health Organization (WHO) Country Profiles: https://apps.who.int/immunization_monitoring/globalsummary 

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Appendix B-16 

Appendix B

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