EX-10.6



 Exhibit 10.6 

SANTA MARIA BIOTHERAPEUTICS, INC. 

2012 EQUITY INCENTIVE PLAN 

EFFECTIVE AS OF NOVEMBER 26, 2012 







 SANTA MARIA BIOTHERAPEUTICS, INC. 

2012 EQUITY INCENTIVE PLAN 

EFFECTIVE AS OF NOVEMBER 26, 2012 

SECTION 1. INTRODUCTION. 
 The
Company’s Board of Directors adopted the Santa Maria Biotherapeutics, Inc. 2012 Equity Incentive Plan effective as of the Adoption Date subject to obtaining Company stockholder approval as provided in Section 15 below. Awards granted under
the Plan prior to the Stockholder Approval Date may not be exercised or Shares released to any Participant until such stockholder approval is obtained. 

The purpose of the Plan is to promote the long-term success of the Company and the creation of stockholder value by offering Key Employees an
opportunity to acquire a proprietary interest in the success of the Company, or to increase such interest, and to encourage such Key Employees to continue to provide services to the Company and to attract new individuals with outstanding
qualifications. 
 The Plan seeks to achieve this purpose by providing for Awards in the form of Options (which may constitute Incentive
Stock Options or Nonstatutory Stock Options), Stock Appreciation Rights, Restricted Stock Grants and/or Stock Units. 
 Capitalized terms
shall have the meaning provided in Section 2 unless otherwise provided in this Plan or any related Stock Option Agreement, SAR Agreement, Restricted Stock Grant Agreement or Stock Unit Agreement. 

SECTION 2. DEFINITIONS. If a Participant’s employment agreement or Award Agreement (or other written agreement executed by and between Participant
and the Company) expressly includes defined terms that expressly are different from and/or conflict with the defined terms contained in this Plan then the defined terms contained in the employment agreement or Award Agreement (or other written
agreement executed by and between Participant and the Company) shall govern and shall supersede the definitions provided in this Plan. 
 (a)
“Adoption Date” means November 26, 2012. 
 (b) “Affiliate” means any entity other than a Subsidiary,
if the Company and/or one or more Subsidiaries own not less than 50% of such entity. 
 (c) “Award” means any award of an
Option, SAR, Restricted Stock Grant or Stock Unit under the Plan. 
 (d) “Board” means the Board of Directors of the
Company, as constituted from time to time. 

  
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 (e) “California Participant” means a Participant whose Award was issued in
reliance on Section 25102(o) of the California Corporations Code. 
 (f) “Call Equivalent Position” means the term
“call equivalent position” as defined under Rule 16a-1(b) of the Exchange Act. 
 (g) “Cashless Exercise” means,
to the extent that a Stock Option Agreement so provides and as permitted by applicable law and in accordance with any procedures established by the Committee, an arrangement whereby payment of some or all of the aggregate Exercise Price may be made
all or in part by delivery of an irrevocable direction to a securities broker to sell Shares and to deliver all or part of the sale proceeds to the Company. Cashless Exercise may also be utilized to satisfy an Option’s tax withholding
obligations as provided in Section 14(b). 
 (h) “Cause” means, with respect to a Participant, the occurrence of any of
the following: (i) a conviction of a Participant for a felony crime or the failure of a Participant to contest prosecution for a felony crime, or (ii) a Participant’s misconduct, fraud, disloyalty or dishonesty (as such terms may be
defined by the Committee in its sole discretion), or (iii) any unauthorized use or disclosure of confidential information or trade secrets by a Participant, or (iv) a Participant’s negligence, malfeasance, breach of fiduciary duties,
neglect of duties, or (v) any material violation by a Participant of a written Company or Subsidiary or Affiliate policy or any material breach by a Participant of a written agreement with the Company or Subsidiary or Affiliate, or
(vi) any other act or omission by a Participant that, in the opinion of the Committee, could reasonably be expected to adversely affect the Company’s or a Subsidiary’s or an Affiliate’s business, financial condition, prospects
and/or reputation. In each of the foregoing subclauses (i) through (vi), whether or not a “Cause” event has occurred will be determined by the Committee in its sole discretion or, in the case of Participants who are directors or
Officers or Section 16 Persons, the Board, each of whose determination shall be final, conclusive and binding. A Participant’s Service shall be deemed to have terminated for Cause if, after the Participant’s Service has terminated,
facts and circumstances are discovered that would have justified a termination for Cause, including, without limitation, violation of material Company policies or breach of noncompetition, confidentiality or other restrictive covenants that may
apply to the Participant. 
 (i) “Change in Control” means the occurrence of any of the following: 

(i) the merger, consolidation, recapitalization, or reorganization of Company, other than a merger, consolidation,
recapitalization or reorganization which would result in the voting securities of Company outstanding immediately prior thereto continuing to represent (either by remaining outstanding or by being converted into voting securities of the surviving
entity) more than fifty percent (50%) of the total voting power represented by the voting securities of Company or such surviving entity outstanding immediately after such merger, consolidation, recapitalization or reorganization; 

  
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 (ii) the sale or disposition by Company’s stockholders of more than fifty
percent (50%) of the total voting securities of Company; 
 (iii) a complete liquidation or dissolution of the Company;

 (iv) the sale or disposition by Company of all or substantially all of its assets; or 

(v) the exclusive licensing to a third party of all or substantially all of Company’s intellectual property. 

Notwithstanding the foregoing, the following transactions shall not constitute a Change in Control: (i) a transaction the
sole purpose of which is to change the state of the Company’s incorporation or to create a holding company that will be owned in substantially the same proportions by the persons who held the Company’s securities immediately before such
transaction; (ii) a transaction or series of related transactions involving the sale of securities by the Company primarily for financing purposes; (iii) a merger or consolidation involving only the Company and one or more companies under
common management control with the Company; or (iv) an IPO. If the timing of payments provided under an Award agreement is based on or triggered by a Change in Control then, to extent necessary to avoid violating Code Section 409A, a
Change in Control must also constitute a “change in control event” (as defined under Code Section 409A regulations and applicable guidance). 

(j) “Code” means the Internal Revenue Code of 1986, as amended, and the regulations and interpretations promulgated
thereunder. 
 (k) “Committee” means a committee consisting of members of the Board that is appointed by the Board (as
described in Section 3) to administer the Plan. If no Committee has been appointed, the full Board shall constitute the Committee. 

(l) “Common Stock” means the Company’s common stock, par value $0.0001 per Share, and any other securities into which
such shares are changed, for which such shares are exchanged or which may be issued in respect thereof. 
 (m) “Company”
means Santa Maria Biotherapeutics, Inc., a Delaware corporation. 
 (n) “Consultant” means an individual (or entity) which
performs bona fide services to the Company, a Parent, a Subsidiary or an Affiliate other than as an Employee or Non-Employee Director. 
 (o)
“Disability” means that the Participant is classified as disabled under a long-term disability policy of the Company or, if no such policy applies, the Participant is unable to engage in any substantial gainful activity by reason of
any medically determinable physical or mental impairment which can be expected to result in death or which has lasted or can be expected to last for a continuous period of not less than 12 months. The Disability of a Key Employee shall be determined
solely by the Committee on the basis of such medical evidence as the Committee deems warranted under the circumstances. 

  
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 (p) “Employee” means any individual who is a common-law employee of the Company,
or of a Parent, or of a Subsidiary or of an Affiliate. 
 (q) “Exchange Act” means the Securities Exchange Act of 1934, as
amended. 
 (r) “Exercise Price” means, in the case of an Option, the amount for which a Share may be purchased upon
exercise of such Option, as specified in the applicable Stock Option Agreement. “Exercise Price,” in the case of a SAR, means an amount, as specified in the applicable SAR Agreement, which is subtracted from the Fair Market Value in
determining the amount payable to a Participant upon exercise of such SAR. 
 (s) “Fair Market Value” means the market price
of a Share, determined by the Committee as follows: 
 (i) If the Shares were traded on a stock exchange (such as the New
York Stock Exchange, NYSE Amex, the NASDAQ Global Market or NASDAQ Capital Market) at the time of determination, then the Fair Market Value shall be equal to the regular session closing price for such stock as reported by such exchange (or the
exchange or market with the greatest volume of trading in the Shares) on the date of determination, or if there were no sales on such date, on the last date preceding such date on which a closing price was reported; 

(ii) If the Shares were traded on the OTC Bulletin Board at the time of determination, then the Fair Market Value shall be
equal to the last-sale price reported by the OTC Bulletin Board for such date, or if there were no sales on such date, on the last date preceding such date on which a sale was reported; and 

(iii) If neither of the foregoing provisions is applicable, then the Fair Market Value shall be determined by the Committee in
good faith using a reasonable application of a reasonable valuation method as the Committee deems appropriate. 
 Whenever possible, the
determination of Fair Market Value by the Committee shall be based on the prices reported by the applicable exchange or the OTC Bulletin Board, as applicable, or a nationally recognized publisher of stock prices or quotations (including an
electronic on-line publication). Such determination shall be conclusive and binding on all persons. 
 (t) “Incentive Stock
Option” or “ISO” means an incentive stock option described in Code section 422. 
 (u) “IPO” means
an initial public offering by the Company of its equity securities pursuant to an effective registration statement filed with the SEC. 
 (v)
“Key Employee” means an Employee, Non-Employee Director or Consultant who has been selected by the Committee to receive an Award under the Plan. 

  
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 (w) “Net Exercise” means, to the extent that a Stock Option Agreement so
provides and as permitted by applicable law, an arrangement pursuant to which the number of Shares issued to the Optionee in connection with the Optionee’s exercise of the Option will be reduced by the Company’s retention of a portion of
such Shares. Upon such a net exercise of an Option, the Optionee will receive a net number of Shares that is equal to (i) the number of Shares as to which the Option is being exercised minus (ii) the quotient (rounded down to the nearest
whole number) of the aggregate Exercise Price of the Shares being exercised divided by the Fair Market Value of a Share on the Option exercise date. The number of Shares covered by clause (ii) will be retained by the Company and not delivered
to the Optionee. No fractional Shares will be created as a result of a Net Exercise and the Optionee must contemporaneously pay for any portion of the aggregate Exercise Price that is not covered by the Shares retained by the Company under clause
(ii). The number of Shares delivered to the Optionee may be further reduced if Net Exercise is utilized under Section 14(b) to satisfy applicable tax withholding obligations. 

(x) “Non-Employee Director” means a member of the Board who is not an Employee. 

(y) “Nonstatutory Stock Option” or “NSO” means a stock option that is not an ISO. 

(z) “Officer” means an individual who is an officer of the Company within the meaning of Rule 16a-1(f) of the Exchange Act.

 (aa) “Option” means an ISO or NSO granted under the Plan entitling the Optionee to purchase Shares under the Plan as
provided in Section 6. 
 (bb) “Optionee” means an individual, estate or other entity that holds an Option. 

(cc) “Parent” means any corporation (other than the Company) in an unbroken chain of corporations ending with the Company, if
each of the corporations other than the Company owns stock possessing fifty percent (50%) or more of the total combined voting power of all classes of stock in one of the other corporations in such chain. A corporation that attains the status
of a Parent on a date after the Adoption Date shall be considered a Parent commencing as of such date. 
 (dd) “Participant”
means an individual or estate or other entity that holds an Award. 
 (ee) “Plan” means this Santa Maria Biotherapeutics,
Inc. 2012 Equity Incentive Plan as it may be amended from time to time. 
 (ff) “Put Equivalent Position” means the term
“put equivalent position” as defined under Rule 16a-1(h) of the Exchange Act. 
 (gg) “Re-Price” means that the
Company has lowered or reduced the Exercise Price of outstanding Options and/or outstanding SARs for any Participant(s) in a manner described by SEC Regulation S-K Item 402(d)(2)(viii) (or as described in any successor provision(s) or
definition(s)). 

  
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 (hh) “Restricted Stock Grant” means Shares awarded under the Plan as provided in
Section 9. 
 (ii) “Restricted Stock Grant Agreement” means the agreement described in Section 9 evidencing each
Award of a Restricted Stock Grant. 
 (jj) “SAR Agreement” means the agreement described in Section 8 evidencing each
Award of a Stock Appreciation Right. 
 (kk) “SEC” means the Securities and Exchange Commission. 

(ll) “Section 16 Persons” means those Officers or directors or Non-Employee Directors or other persons who are subject to
Section 16 of the Exchange Act. 
 (mm) “Section 280G Approval” means the separate approval by stockholders owning more
than 75% of the voting power of all outstanding stock of the Company entitled to vote immediately before a Change in Control which approval shall be obtained in compliance with the requirements of Code Section 280G(b)(5)(B), as amended,
including any successor thereof, and the regulations promulgated thereunder, as determined by the Committee in its sole discretion. 
 (nn)
“Securities Act” means the Securities Act of 1933, as amended. 
 (oo) “Separation From Service” means a
Participant’s separation from service with the Company within the meaning of Code Section 409A. 
 (pp) “Service”
means service as an Employee, Non-Employee Director or Consultant. Service will be deemed terminated as soon as the entity to which Service is being provided is no longer either (i) the Company, (ii) a Parent, (iii) a Subsidiary or
(iv) an Affiliate. The Committee determines when Service commences and when Service terminates. The Committee may determine whether any Company transaction, such as a sale or spin-off of a division or subsidiary that employs a Participant,
shall be deemed to result in termination of Service for purposes of any affected Awards, and the Committee’s decision shall be final, conclusive and binding. 

(qq) “Share” means one share of Common Stock. 

(rr) “Stock Appreciation Right or SAR” means a stock appreciation right awarded under the Plan as provided in Section 8.

 (ss) “Stock Option Agreement” means the agreement described in Section 6 evidencing each Award of an Option. 

(tt) “Stock Unit” means a bookkeeping entry representing the equivalent of one Share awarded under the Plan as provided in
Section 10. 
 (uu) “Stock Unit Agreement” means the agreement described in Section 10 evidencing each Award of
Stock Units. 

  
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 (vv) “Stockholder Approval Date” means the date that the Company’s
stockholders approve this Plan. 
 (ww) “Stockholders Agreement” means any applicable agreement between the Company’s
stockholders and/or investors that provides certain rights and obligations for stockholders. 
 (xx) “Subsidiary” means any
corporation (other than the Company) in an unbroken chain of corporations beginning with the Company, if each of the corporations other than the last corporation in the unbroken chain owns stock possessing fifty percent (50%) or more of the
total combined voting power of all classes of stock in one of the other corporations in such chain. A corporation that attains the status of a Subsidiary on a date after the Adoption Date shall be considered a Subsidiary commencing as of such date.

 (yy) “Termination Date” means the date on which a Participant’s Service terminates as determined by the Committee.

 (zz) “10-Percent Shareholder” means an individual who owns more than ten percent (10%) of the total combined voting
power of all classes of outstanding stock of the Company, its Parent or any of its Subsidiaries. In determining stock ownership, the attribution rules of section 424(d) of the Code shall be applied. 

SECTION 3. ADMINISTRATION. 
 (a)
Committee Composition. A Committee appointed by the Board shall administer the Plan. The Board shall designate one of the members of the Committee as chairperson. Members of the Committee shall serve for such period of time as the Board may
determine and shall be subject to removal by the Board at any time. The Board may also at any time terminate the functions of the Committee and reassume all powers and authority previously delegated to the Committee. 

Effective with the Shares being publicly traded or the Company being subject to the reporting requirements of the Exchange Act, with respect to
Awards to Section 16 Persons, the Committee shall consist either (i) solely of two or more individuals who satisfy the requirements of Rule 16b-3 (or its successor) under the Exchange Act or (ii) of the full Board. The Board may also
appoint one or more separate committees of the Board, each composed of directors of the Company who need not qualify under Rule 16b-3, who may administer the Plan with respect to Key Employees who are not Section 16 Persons, may grant Awards
under the Plan to such Key Employees and may determine all terms of such Awards. To the extent permitted by applicable law, the Board may also appoint a committee, composed of one or more officers of the Company, that may authorize Awards to
Employees (who are not Section 16 Persons) within parameters specified by the Board and consistent with any limitations imposed by applicable law. 

  
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 (b) Authority of the Committee. Subject to the provisions of the Plan, the Committee shall
have full authority and discretion to take any actions it deems necessary or advisable for the administration of the Plan. Such actions shall include without limitation: 

(i) selecting Key Employees who are to receive Awards under the Plan; 

(ii) determining the type, number, vesting requirements, performance conditions (if any) and their degree of satisfaction, and other features
and conditions of such Awards and amending such Awards; 
 (iii) correcting any defect, supplying any omission, or reconciling or clarifying
any inconsistency in the Plan or any Award agreement; 
 (iv) accelerating the vesting, or extending the post-termination exercise term, or
waiving restrictions, of Awards at any time and under such terms and conditions as it deems appropriate; 
 (v) Re-Pricing outstanding
Options or SARs, without the approval of Company stockholders; 
 (vi) interpreting the Plan and any Award agreements; 

(vii) making all other decisions relating to the operation of the Plan; and 

(viii) granting Awards to Key Employees who are foreign nationals on such terms and conditions different from those specified in the Plan,
which may be necessary or desirable to foster and promote achievement of the purposes of the Plan, and adopting such modifications, procedures, and/or subplans (with any such subplans attached as appendices to the Plan) and the like as may be
necessary or desirable to comply with provisions of the laws or regulations of other countries or jurisdictions to ensure the viability of the benefits from Awards granted to Participants employed in such countries or jurisdictions, or to meet the
requirements that permit the Plan to operate in a qualified or tax efficient manner, and/or comply with applicable foreign laws or regulations. 

The Committee may adopt such rules or guidelines, as it deems appropriate to implement the Plan. The Committee’s determinations under the
Plan shall be final, conclusive and binding on all persons. The Committee’s decisions and determinations need not be uniform and may be made selectively among Participants in the Committee’s sole discretion. The Committee’s decisions
and determinations will be afforded the maximum deference provided by applicable law. 
 (c) Indemnification. To the maximum extent
permitted by applicable law, each member of the Committee, or of the Board, or any persons (including without limitation Employees and Officers) who are delegated by the Board or Committee to perform administrative functions in connection with the
Plan, shall be indemnified and held harmless by the Company against and from (i) any loss, cost, liability, or expense that 

  
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may be imposed upon or reasonably incurred by him or her in connection with or resulting from any claim, action, suit, or proceeding to which he or she may be a party or in which he or she may be
involved by reason of any action taken or failure to act under the Plan or any Award agreement, and (ii) from any and all amounts paid by him or her in settlement thereof, with the Company’s approval, or paid by him or her in satisfaction
of any judgment in any such claim, action, suit, or proceeding against him or her, provided he or she shall give the Company an opportunity, at its own expense, to handle and defend the same before he or she undertakes to handle and defend it on his
or her own behalf. The foregoing right of indemnification shall not be exclusive of any other rights of indemnification to which such persons may be entitled under the Company’s Certificate of Incorporation or Bylaws, by contract, as a matter
of law, or otherwise, or under any power that the Company may have to indemnify them or hold them harmless. 
 SECTION 4. GENERAL. 

(a) Eligibility. Only Employees, Non-Employee Directors and Consultants shall be eligible for designation as Key Employees by the
Committee. 
 (b) Incentive Stock Options. Only Key Employees who are common-law employees of the Company, a Parent or a Subsidiary
shall be eligible for the grant of ISOs. In addition, a Key Employee who is a 10-Percent Shareholder shall not be eligible for the grant of an ISO unless the requirements set forth in section 422(c)(5) of the Code are satisfied. If and to the extent
that any Shares are issued under a portion of any Option that exceeds the $100,000 limitation of Section 422 of the Code, such Shares shall not be treated as issued under an ISO notwithstanding any designation otherwise. Certain decisions,
amendments, interpretations and actions by the Committee and certain actions by a Participant may cause an Option to cease to qualify as an ISO pursuant to the Code and by accepting an Option the Participant agrees in advance to such disqualifying
action taken by either the Participant, the Committee or the Company. 
 (c) Restrictions on Shares. Any Shares issued pursuant to an
Award shall be subject to such Company policies, rights of repurchase, rights of first refusal and other transfer restrictions as the Committee may determine. Such restrictions shall apply in addition to any restrictions that may apply to holders of
Shares generally and shall also comply to the extent necessary with applicable law. In no event shall the Company be required to issue fractional Shares under this Plan. 

(d) Beneficiaries. A Participant may designate one or more beneficiaries with respect to an Award by timely filing the prescribed form
with the Company. A beneficiary designation may be changed by filing the prescribed form with the Company at any time before the Participant’s death. If no beneficiary was designated or if no designated beneficiary survives the Participant,
then after a Participant’s death any vested Award(s) shall be transferred or distributed to the Participant’s estate. 
 (e)
Performance Conditions. The Committee may, in its discretion, include performance conditions in any Award. 

  
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 (f) Stockholder Rights. A Participant, or a transferee of a Participant, shall have no
rights as a stockholder (including without limitation voting rights or dividend or distribution rights) with respect to any Common Stock covered by an Award until such person becomes entitled to receive such Common Stock, has satisfied any
applicable withholding or tax obligations relating to the Award and the Common Stock has been issued to the Participant. No adjustment shall be made for cash or stock dividends or other rights for which the record date is prior to the date when such
Common Stock is issued, except as expressly provided in Section 11. The issuance of an Award may be subject to and conditioned upon the Participant’s agreement to become a party to a Stockholders Agreement and be bound by its terms. 

(g) Buyout of Awards. The Committee may at any time offer to buy out, for a payment in cash or cash equivalents (including without
limitation Shares issued at Fair Market Value that may or may not be issued under this Plan), an Award previously granted based upon such terms and conditions as the Committee shall establish. 

(h) Termination of Service. Unless the applicable Award agreement or employment agreement provides otherwise (and in such case, the
Award or employment agreement shall govern as to the consequences of a termination of Service for such Awards subject to Section 4(i)), the following rules shall govern the vesting, exercisability and term of outstanding Awards held by a
Participant in the event of termination of such Participant’s Service (in all cases subject to the term of the Option or SAR as applicable): 

(i) if the Service of a Participant is terminated for Cause, then all Options, SARs, unvested portions of Stock Units and unvested portions of
Restricted Stock Grants shall terminate and be forfeited immediately without consideration as of the Termination Date (except for repayment of any amounts the Participant had paid to the Company to acquire unvested Shares underlying the forfeited
Awards); 
 (ii) if the Service of Participant is terminated due to the Participant’s death or Disability, then the vested portion of
his/her then-outstanding Options/SARs may be exercised by such Participant or his or her personal representative within six months after the Termination Date and all unvested portions of any outstanding Awards shall be forfeited without
consideration as of the Termination Date (except for repayment of any amounts the Participant had paid to the Company to acquire unvested Shares underlying the forfeited Awards); and 

(iii) if the Service of Participant is terminated for any reason other than for Cause or other than due to death or Disability, then the vested
portion of his/her then-outstanding Options/SARs may be exercised by such Participant within three months after the Termination Date and all unvested portions of any outstanding Awards shall be forfeited without consideration as of the Termination
Date (except for repayment of any amounts the Participant had paid to the Company to acquire unvested Shares underlying the forfeited Awards). 

  
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 (i) California Participants. Awards to California Participants shall also be subject to
the following terms regarding the time period to exercise vested Options or SARs after termination of Service. These additional terms shall apply until such time that the Shares are publicly traded and/or the Company is subject to the reporting
requirements of the Exchange Act: In the event of termination of a Participant’s Service, (i) if such termination was for reasons other than death or Disability or Cause, the Participant shall have at least 30 days after the date of such
termination to exercise any of his/her vested outstanding Options or SARs (but in no event later than the expiration of the term of such Options or SARs established by the Committee as of the Award date) or (ii) if such termination was due to
death or Disability, the Participant shall have at least six months after the date of such termination to exercise any of his/her vested outstanding Options or SARs (but in no event later than the expiration of the term of such Options or SARs
established by the Committee as of the Award date). 
 (j) Suspension or Termination of Awards. If at any time (including after a
notice of exercise has been delivered) the Committee (or the Board), reasonably believes that a Participant has committed an act of Cause (which includes a failure to act), the Committee (or Board) may suspend the Participant’s right to
exercise any Option or SAR (or vesting of Restricted Stock Grants or Stock Units) pending a determination of whether there was in fact an act of Cause. If the Committee (or the Board) determines a Participant has committed an act of Cause, neither
the Participant nor his or her estate shall be entitled to exercise any outstanding Option or SAR whatsoever and all of Participant’s outstanding Awards shall then terminate without consideration. Any determination by the Committee (or the
Board) with respect to the foregoing shall be final, conclusive and binding on all interested parties. 
 (k) Code Section 409A.
Notwithstanding anything in the Plan to the contrary, the Plan and Awards granted hereunder are intended to comply with the requirements of Code Section 409A and shall be interpreted in a manner consistent with such intention. In the event that
any provision of the Plan or an Award agreement is determined by the Committee to not comply with the applicable requirements of Code Section 409A or the Treasury Regulations or other guidance issued thereunder, the Committee shall have the
authority to take such actions and to make such changes to the Plan or an Award Agreement as the Committee deems necessary to comply with such requirements (including without limitation, after the grant date of an Award, increasing the Exercise
Price to equal what was the Fair Market Value on the grant date of Award). Each payment to a Participant made pursuant to this Plan shall be considered a separate payment and not one of a series of payments for purposes of Code Section 409A.
Notwithstanding the foregoing or anything elsewhere in the Plan or an Award Agreement to the contrary, if upon a Participant’s Separation From Service he/she is then a “specified employee” (as defined in Code Section 409A), then
solely to the extent necessary to comply with Code Section 409A and avoid the imposition of taxes under Code Section 409A, the Company shall defer payment of “nonqualified deferred compensation” subject to Code Section 409A
payable as a result of and within six (6) months following such Separation From Service under this Plan until the earlier of (i) the first business day of the seventh month following the Participant’s Separation From Service, or
(ii) ten (10) days after the Company receives written confirmation of the 

  
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Participant’s death. Any such delayed payments shall be made without interest. In no event whatsoever shall the Company be liable for any additional tax, interest or penalties that may be
imposed on a Participant by Code Section 409A or any damages for failing to comply with Code Section 409A. 
 (l) Electronic
Communications. Subject to compliance with applicable law and/or regulations, an Award agreement or other documentation or notices relating to the Plan and/or Awards may be communicated to Participants by electronic media. 

(m) Unfunded Plan. Insofar as it provides for Awards, the Plan shall be unfunded. Although bookkeeping accounts may be established with
respect to Participants who are granted Awards under this Plan, any such accounts will be used merely as a bookkeeping convenience. The Company shall not be required to segregate any assets which may at any time be represented by Awards, nor shall
this Plan be construed as providing for such segregation, nor shall the Company or the Committee be deemed to be a trustee of stock or cash to be awarded under the Plan. 

(n) Liability of Company Plan. The Company (or members of the Board or Committee) shall not be liable to a Participant or other persons
as to: (i) the non-issuance or sale of Shares as to which the Company has been unable to obtain from any regulatory body having jurisdiction the authority deemed by the Company’s counsel to be necessary to the lawful issuance and sale of
any Shares hereunder; and (ii) any unexpected or adverse tax consequence or any tax consequence expected, but not realized, by any Participant or other person due to the grant, receipt, exercise or settlement of any Award granted under this
Plan. 
 (o) Reformation. In the event any provision of this Plan shall be held illegal or invalid for any reason, such provisions
will be reformed by the Board if possible and to the extent needed in order to be held legal and valid. If it is not possible to reform the illegal or invalid provisions then the illegality or invalidity shall not affect the remaining parts of this
Plan, and this Plan shall be construed and enforced as if the illegal or invalid provision had not been included. 
 (p) Successor
Provision. Any reference to a statute, rule or regulation, or to a section of a statute, rule or regulation, is a reference to that statute, rule, regulation, or section as amended from time to time, both before and after the Adoption Date and
including any successor provisions. 
 (q) Governing Law. This Plan, and (unless otherwise provided in the Award Agreement) all
Awards, shall be construed in accordance with and governed by the laws of the State of Delaware, but without regard to its conflict of law provisions. The Committee may provide that any dispute as to any Award shall be presented and determined in
such forum as the Committee may specify, including through binding arbitration. Unless otherwise provided in the Award Agreement, recipients of an Award under the Plan are deemed to submit to the exclusive jurisdiction and venue of the federal or
state courts of California to resolve any and all issues that may arise out of or relate to the Plan or any related Award Agreement. 

  
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 SECTION 5. SHARES SUBJECT TO PLAN AND SHARE LIMITS. 

(a) Basic Limitations. The Common Stock issuable under the Plan shall be authorized but unissued Shares or treasury Shares. Subject to
adjustment as provided in Section 11, the maximum aggregate number of Shares that may be issued: 
 (i) under the Plan shall not exceed
5,441,999 Shares (the “Share Limit”); and 
 (ii) pursuant to the exercise of ISOs granted under this Plan shall not exceed
5,441,999 Shares (the “ISO Limit”). 
 (b) Share Utilization. If Awards are forfeited or are terminated for any reason
(including the Company’s repurchase of unvested Shares from either an Option that was early exercised or from a Restricted Stock Grant), then the forfeited/terminated/repurchased Shares underlying such Awards shall not be counted toward the
Share Limit. If exercised SARs or Stock Units are settled in Shares, then only the number of Shares (if any) actually issued in settlement of such SARs or Stock Units shall be counted against the Share Limit. If a Participant pays the Exercise Price
by Net Exercise or by surrendering previously owned Shares (or by stock attestation) and/or, as permitted by the Committee, pays any withholding tax obligation with respect to an Award by Net Exercise or by electing to have Shares withheld or
surrendering previously owned Shares (or by stock attestation), the surrendered Shares and the Shares withheld to pay taxes shall not be counted toward the Share Limit. Any Shares that are delivered and any Awards that are granted by, or become
obligations of, the Company, as a result of the assumption by the Company of, or in substitution for, outstanding awards previously granted by another entity (as provided in Sections 6(e), 8(f), 9(e) or 10(e)) shall not be counted toward the Share
Limit or ISO Limit. 
 (c) Dividend Equivalents. Any dividend equivalents distributed under the Plan shall not be counted against the
Share Limit. 
 SECTION 6. TERMS AND CONDITIONS OF OPTIONS. 

(a) Stock Option Agreement. Each Award of an Option under the Plan shall be evidenced by a Stock Option Agreement between the Optionee
and the Company. Such Option shall be subject to all applicable terms and conditions of the Plan and may be subject to any other terms and conditions that are not inconsistent with the Plan (including without limitation any performance conditions).
The provisions of the various Stock Option Agreements entered into under the Plan need not be identical. The Stock Option Agreement shall also specify whether the Option is an ISO and if not specified then the Option shall be an NSO. 

(b) Number of Shares. Each Stock Option Agreement shall specify the number of Shares that are subject to the Option and shall provide
for the adjustment of such number in accordance with Section 11. 

  
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 (c) Exercise Price. An Option’s Exercise Price shall be established by the Committee
and set forth in a Stock Option Agreement. Except with respect to outstanding stock options being assumed or Options being granted in exchange for cancellation of options granted by another issuer as provided under Section 6(e), the Exercise
Price of an Option shall not be less than 100% of the Fair Market Value (110% for 10-Percent Shareholders in the case of ISOs) of a Share on the date of Award. 

(d) Exercisability and Term. Each Stock Option Agreement shall specify the date when all or any installment of the Option is to become
vested and/or exercisable. The Stock Option Agreement shall also specify the term of the Option; provided, however that the term of an Option shall in no event exceed ten (10) years from the date of Award. An ISO that is granted to a 10-Percent
Shareholder shall have a maximum term of five (5) years. No Option can be exercised after the expiration date specified in the applicable Stock Option Agreement. A Stock Option Agreement may provide for accelerated exercisability in the event
of the Optionee’s death, Disability or retirement or other events. A Stock Option Agreement may permit an Optionee to exercise an Option before it is vested (an “early exercise”), subject to the Company’s right of repurchase at
the original Exercise Price of any Shares acquired under the unvested portion of the Option which right of repurchase shall lapse at the same rate the Option would have vested had there been no early exercise. In no event shall the Company be
required to issue fractional Shares upon the exercise of an Option and the Committee may specify a minimum number of Shares that must be purchased in any one Option exercise. 

(e) Modifications or Assumption of Options. Within the limitations of the Plan, the Committee may modify, extend or assume outstanding
Options or may accept the cancellation of outstanding stock options (whether granted by the Company or by another issuer) in return for the grant of new Options for the same or a different number of Shares and at the same or a different Exercise
Price. For the avoidance of doubt, the Committee may in its discretion Re-Price outstanding Options provided, however, that the new Exercise Price of a Re-Priced Option shall not be less than the Fair Market Value on the date of the Re-Pricing. No
modification of an Option shall, without the consent of the Optionee, impair his or her rights or increase his or her obligations under such Option. 

(f) Assignment or Transfer of Options. Except as otherwise provided in the applicable Stock Option Agreement and then only to the extent
permitted by applicable law, no Option shall be transferable by the Optionee other than by will or by the laws of descent and distribution. Except as otherwise provided in the applicable Stock Option Agreement, an Option may be exercised during the
lifetime of the Optionee only by Optionee or by the guardian or legal representative of the Optionee. Except as otherwise provided in the applicable Stock Option Agreement, no Option or interest therein may be subject to a short position or a Call
Equivalent Position or Put Equivalent Position, nor may any Option or interest therein be gifted, transferred, assigned, alienated, pledged, hypothecated, attached, sold, or encumbered by the Optionee during his/her lifetime, whether by operation of
law or otherwise, or be made subject to execution, attachment or similar process. 

  
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 (g) Additional Disclosure. Solely to the extent that the Company is relying on the
exemption from registration under Section 12(g) of the Exchange Act, as provided by Rule 12h-1(f) of the Exchange Act, the Company shall provide (or make available to) Optionees with the additional disclosures required by Rule 12h-1(f)(1)(vi)
of the Exchange Act. As a condition to receiving these additional disclosures, an Optionee shall agree in writing to keep the information provided in these additional disclosures confidential. If an Optionee does not agree in writing to keep this
information confidential, then the Company shall not be required to provide such Optionee with the additional disclosures required by this Section 6(g). 

SECTION 7. PAYMENT FOR OPTION SHARES. 

(a) General Rule. The entire Exercise Price of Shares issued upon exercise of Options shall be payable in cash (or check) at the time
when such Shares are purchased by the Optionee, except as follows and if so provided for in an applicable Stock Option Agreement: 

(i) In the case of an ISO granted under the Plan, payment shall be made only pursuant to the express provisions of the
applicable Stock Option Agreement. The Stock Option Agreement may specify that payment may be made in any form(s) described in this Section 7. 

(ii) In the case of an NSO granted under the Plan, the Committee may in its discretion, at any time accept payment in any
form(s) described in this Section 7. 
 (b) Surrender of Stock. To the extent that the Committee makes this Section 7(b)
applicable to an Option in a Stock Option Agreement, payment for all or any part of the Exercise Price may be made with Shares which have already been owned by the Optionee for such duration as shall be specified by the Committee. Such Shares shall
be valued at their Fair Market Value on the date when the new Shares are purchased under the Plan. 
 (c) Cashless Exercise. To the
extent that the Committee makes this Section 7(c) applicable to an Option in a Stock Option Agreement, payment for all or a part of the Exercise Price may be made through Cashless Exercise. 

(d) Net Exercise. To the extent that the Committee makes this Section 7(d) applicable to an Option in a Stock Option Agreement,
payment for all or a part of the Exercise Price may be made through Net Exercise. 
 (e) Other Forms of Payment. To the extent that
the Committee makes this Section 7(e) applicable to an Option in a Stock Option Agreement, payment may be made in any other form that is consistent with applicable laws, regulations and rules and approved by the Committee. 

  
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 SECTION 8. TERMS AND CONDITIONS OF STOCK APPRECIATION RIGHTS. 

(a) SAR Agreement. Each Award of a SAR under the Plan shall be evidenced by a SAR Agreement between the Participant and the Company.
Such SAR shall be subject to all applicable terms of the Plan and may be subject to any other terms that are not inconsistent with the Plan (including without limitation any performance conditions). A SAR Agreement may provide for a maximum limit on
the amount of any payout notwithstanding the Fair Market Value on the date of exercise of the SAR. The provisions of the various SAR Agreements entered into under the Plan need not be identical. SARs may be granted in consideration of a reduction in
the Participant’s other compensation. 
 (b) Number of Shares. Each SAR Agreement shall specify the number of Shares to which the
SAR pertains and is subject to adjustment of such number in accordance with Section 11. 
 (c) Exercise Price. Each SAR Agreement
shall specify the Exercise Price. A SAR Agreement may specify an Exercise Price that varies in accordance with a predetermined formula while the SAR is outstanding. Except with respect to outstanding stock appreciation rights being assumed or SARs
being granted in exchange for cancellation of stock appreciation rights granted by another issuer as provided under Section 8(f), the Exercise Price of a SAR shall not be less than 100% of the Fair Market Value on the date of Award. 

(d) Exercisability and Term. Each SAR Agreement shall specify the date when all or any installment of the SAR is to become exercisable.
The SAR Agreement shall also specify the term of the SAR which shall not exceed ten years from the date of Award. No SAR can be exercised after the expiration date specified in the applicable SAR Agreement. A SAR Agreement may provide for
accelerated exercisability in the event of the Participant’s death, or Disability or other events. SARs may be awarded in combination with Options or other Awards, and such an Award may provide that the SARs will not be exercisable unless the
related Options or other Awards are forfeited. A SAR may be included in an ISO only at the time of Award but may be included in an NSO at the time of Award or at any subsequent time, but not later than six months before the expiration of such NSO. A
SAR granted under the Plan may provide that it will be exercisable only in the event of a Change in Control. 
 (e) Exercise of SARs.
If, on the date when a SAR expires, the Exercise Price under such SAR is less than the Fair Market Value on such date but any portion of such SAR has not been exercised or surrendered, then such SAR may automatically be deemed to be exercised as of
such date with respect to such portion to the extent so provided in the applicable SAR agreement. Upon exercise of a SAR, the Participant (or any person having the right to exercise the SAR after Participant’s death) shall receive from the
Company (i) Shares, (ii) cash or (iii) any combination of Shares and cash, as the Committee shall determine. The amount of cash and/or the Fair Market Value of Shares received upon exercise of SARs shall, in the aggregate, be equal to
the amount by which the Fair Market Value (on the date of surrender) of the Shares subject to the SARs exceeds the Exercise Price of the Shares. 

  
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 (f) Modification or Assumption of SARs. Within the limitations of the Plan, the Committee
may modify, extend or assume outstanding SARs or may accept the cancellation of outstanding SARs (including stock appreciation rights granted by another issuer) in return for the grant of new SARs for the same or a different number of Shares and at
the same or a different Exercise Price. For the avoidance of doubt, the Committee may in its discretion Re-Price outstanding SARs provided, however, that the new Exercise Price of a Re-Priced SAR shall not be less than the Fair Market Value on the
date of the Re-Pricing. No modification of a SAR shall, without the consent of the Participant, impair his or her rights or increase his or her obligations under such SAR. 

(g) Assignment or Transfer of SARs. Except as otherwise provided in the applicable SAR Agreement and then only to the extent permitted
by applicable law, no SAR shall be transferable by the Participant other than by will or by the laws of descent and distribution. Except as otherwise provided in the applicable SAR Agreement, a SAR may be exercised during the lifetime of the
Participant only by the Participant or by the guardian or legal representative of the Participant. No SAR or interest therein may be transferred, assigned, alienated, pledged, hypothecated, attached, sold, or encumbered by the Participant during his
or her lifetime, whether by operation of law or otherwise, or be made subject to execution, attachment or similar process. 
 SECTION 9. TERMS AND
CONDITIONS FOR RESTRICTED STOCK GRANTS. 
 (a) Restricted Stock Grant Agreement. Each Restricted Stock Grant awarded under the
Plan shall be evidenced by a Restricted Stock Grant Agreement between the Participant and the Company. Each Restricted Stock Grant shall be subject to all applicable terms and conditions of the Plan and may be subject to any other terms and
conditions that are not inconsistent with the Plan (including without limitation any performance conditions). The provisions of the Restricted Stock Grant Agreements entered into under the Plan need not be identical. 

(b) Number of Shares and Payment. Each Restricted Stock Grant Agreement shall specify the number of Shares to which the Restricted Stock
Grant pertains and is subject to adjustment of such number in accordance with Section 11. Restricted Stock Grants may be issued with or without cash consideration under the Plan. 

(c) Vesting Conditions. Each Restricted Stock Grant may or may not be subject to vesting. Vesting shall occur, in full or in
installments, upon satisfaction of the conditions specified in the Restricted Stock Grant Agreement. A Restricted Stock Grant Agreement may provide for accelerated vesting in the event of the Participant’s death, or Disability or other events.

 (d) Voting and Dividend Rights. The holder of a Restricted Stock Grant (irrespective of whether the Shares subject to the
Restricted Stock Grant are vested or unvested) awarded under the Plan shall have the same voting, dividend and other rights 

  
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as the Company’s other stockholders. However, any dividends received on Shares that are unvested (whether such dividends are in the form of cash or Shares) may be subject to the same vesting
conditions and restrictions as the Restricted Stock Grant with respect to which the dividends were paid. Such additional Shares issued as dividends that are subject to the Restricted Stock Grant shall not reduce the number of Shares available for
issuance under Section 5. 
 (e) Modification or Assumption of Restricted Stock Grants. Within the limitations of the Plan, the
Committee may modify or assume outstanding Restricted Stock Grants or may accept the cancellation of outstanding Restricted Stock Grants (including stock granted by another issuer) in return for the grant of new Restricted Stock Grants for the same
or a different number of Shares. No modification of a Restricted Stock Grant shall, without the consent of the Participant, impair his or her rights or increase his or her obligations under such Restricted Stock Grant. 

(f) Assignment or Transfer of Restricted Stock Grants. Except as provided in Section 14, or in a Restricted Stock Grant Agreement, or as
required by applicable law, a Restricted Stock Grant awarded under the Plan shall not be assigned, attached, garnished, optioned, transferred or made subject to any creditor’s process, whether voluntarily, involuntarily or by operation of law.
Any act in violation of this Section 9(f) shall be void. However, this Section 9(f) shall not preclude a Participant from designating a beneficiary pursuant to Section 4(d) nor shall it preclude a transfer of Restricted Stock Grant
Awards by will or pursuant to Section 4(d). 
 SECTION 10. TERMS AND CONDITIONS FOR STOCK UNITS. 

(a) Stock Unit Agreement. Each grant of Stock Units under the Plan shall be evidenced by a Stock Unit Agreement between the Participant
and the Company. Such Stock Units shall be subject to all applicable terms of the Plan and may be subject to any other terms that are not inconsistent with the Plan (including without limitation any performance conditions). The provisions of the
various Stock Unit Agreements entered into under the Plan need not be identical. Stock Units may be granted in consideration of a reduction in the Participant’s other compensation. 

(b) Number of Shares and Payment. Each Stock Unit Agreement shall specify the number of Shares to which the Stock Unit Award pertains
and is subject to adjustment of such number in accordance with Section 11. To the extent that an Award is granted in the form of Stock Units, no cash consideration shall be required of the Award recipients. 

(c) Vesting Conditions. Each Award of Stock Units may or may not be subject to vesting. Vesting shall occur, in full or in installments,
upon satisfaction of the conditions specified in the Stock Unit Agreement. A Stock Unit Agreement may provide for accelerated vesting in the event of the Participant’s death, or Disability or other events. 

(d) Voting and Dividend Rights. The holders of Stock Units shall have no voting rights. Prior to settlement or forfeiture, any Stock
Unit awarded under the Plan may, at the Committee’s discretion, carry with it a right to dividend equivalents. Such right 

  
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entitles the holder to be credited with an amount equal to all cash or Common Stock dividends paid on one Share while the Stock Unit is outstanding. Dividend equivalents may be converted into
additional Stock Units. Settlement of dividend equivalents may be made in the form of cash, in the form of Shares, or in a combination of both. Prior to vesting of the Stock Units, any dividend equivalents accrued on such unvested Stock Units may be
subject to the same vesting conditions and restrictions as the Stock Units to which they attach. 
 (e) Modification or Assumption of
Stock Units. Within the limitations of the Plan, the Committee may modify or assume outstanding Stock Units or may accept the cancellation of outstanding Stock Units (including stock units granted by another issuer) in return for the grant of
new Stock Units for the same or a different number of Shares. No modification of a Stock Unit shall, without the consent of the Participant, impair his or her rights or increase his or her obligations under such Stock Unit. 

(f) Assignment or Transfer of Stock Units. Except as provided in Section 14, or in a Stock Unit Agreement, or as required by
applicable law, Stock Units shall not be assigned, attached, garnished, optioned, transferred or made subject to any creditor’s process, whether voluntarily, involuntarily or by operation of law. Any act in violation of this Section 10(f)
shall be void. However, this Section 10(f) shall not preclude a Participant from designating a beneficiary pursuant to Section 4(d) nor shall it preclude a transfer of Stock Units pursuant to Section 4(d). 

(g) Form and Time of Settlement of Stock Units. Settlement of vested Stock Units may be made in the form of (a) cash,
(b) Shares or (c) any combination of both, as determined by the Committee. The actual number of Stock Units eligible for settlement may be larger or smaller than the number included in the original Award. Methods of converting Stock Units
into cash may include (without limitation) a method based on the average Fair Market Value of Shares over a series of trading days. Except as otherwise provided in a Stock Unit Agreement or a timely completed deferral election, vested Stock Units
shall be settled within thirty days after vesting. The distribution may occur or commence when all vesting conditions applicable to the Stock Units have been satisfied or have lapsed, or it may be deferred, in accordance with applicable law, to a
later specified date. The amount of a deferred distribution may be increased by an interest factor or by dividend equivalents. Until an Award of Stock Units is settled, the number of such Stock Units shall be subject to adjustment pursuant to
Section 11. 
 (h) Creditors’ Rights. A holder of Stock Units shall have no rights other than those of a general creditor of
the Company. Stock Units represent an unfunded and unsecured obligation of the Company, subject to the terms and conditions of the applicable Stock Unit Agreement. 

(i) Additional Disclosure. Solely to the extent that the Company is relying on the exemption from registration under Section 12(g)
of the Exchange Act, as provided by Rule 12h-1(f) of the Exchange Act, the Company shall provide (or make available to) Participants holding Stock Units with the additional disclosures required by Rule 12h-1(f)(1)(vi) of the Exchange Act. As a
condition to receiving these additional disclosures, 

  
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any such Participant shall agree in writing to keep the information provided in these additional disclosures confidential. If any such Participant does not agree in writing to keep this
information confidential, then the Company shall not be required to provide such Participant with the additional disclosures required by this Section 10(i). 

SECTION 11. ADJUSTMENTS. 
 (a)
Adjustments. In the event of a subdivision of the outstanding Shares, a declaration of a dividend payable in Shares, a declaration of a dividend payable in a form other than Shares in an amount that has a material effect on the price of
Shares, a combination or consolidation of the outstanding Shares (by reclassification or otherwise) into a lesser number of Shares, a stock split, a reverse stock split, a reclassification or other distribution of the Shares without the receipt of
consideration by the Company, of or on the Common Stock, a recapitalization, a combination, a spin-off or a similar occurrence, the Committee shall make equitable and proportionate adjustments to: 

(i) the Share Limit and ISO Limit specified in Section 5(a); 

(ii) the number and kind of securities available for Awards (and which can be issued as ISOs) under Section 5; 

(iii) the number and kind of securities covered by each outstanding Award; 

(iv) the Exercise Price under each outstanding Option and SAR; and 

(v) the number and kind of outstanding securities issued under the Plan. 

(b) Participant Rights. Except as provided in this Section 11, a Participant shall have no rights by reason of any issue by the
Company of stock of any class or securities convertible into stock of any class, any subdivision or consolidation of shares of stock of any class, the payment of any stock dividend or any other increase or decrease in the number of shares of stock
of any class. If by reason of an adjustment pursuant to this Section 11, a Participant’s Award covers additional or different shares of stock or securities, then such additional or different shares and the Award in respect thereof shall be
subject to all of the terms, conditions and restrictions which were applicable to the Award and the Shares subject to the Award prior to such adjustment. 

(c) Fractional Shares. Any adjustment of Shares pursuant to this Section 11 shall be rounded down to the nearest whole number of
Shares. Under no circumstances shall the Company be required to authorize or issue fractional shares. To the extent permitted by applicable law, no consideration shall be provided as a result of any fractional shares not being issued or authorized.


  
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 SECTION 12. EFFECT OF A CHANGE IN CONTROL. 

(a) Merger or Reorganization. In the event that there is a Change in Control and/or the Company is a party to a merger or acquisition or
reorganization or similar transaction, outstanding Awards shall be subject to the merger agreement or other applicable transaction agreement. Such agreement may provide, without limitation, that subject to the consummation of the applicable
transaction, for the assumption (or substitution) of outstanding Awards by the surviving corporation or its parent, for their continuation by the Company (if the Company is a surviving corporation), for accelerated vesting or for their cancellation
with or without consideration, in all cases without the consent of the Participant. 
 (b) Acceleration of Vesting. In the event that
a Change in Control occurs and there is no assumption, substitution or continuation of Awards pursuant to Section 12(a), the Committee in its discretion may provide that all Awards shall vest and become exercisable as of immediately before such
Change in Control. For avoidance of doubt, “substitution” includes, without limitation, an Award being replaced by a cash award that provides an equivalent intrinsic value (wherein intrinsic value equals the difference between the market
value of a share and any exercise price). The Committee may also in its discretion include in an Award agreement a requirement that unless Section 280G Approval has been obtained, no acceleration of vesting shall occur with respect to an Award
to the extent that such acceleration would, after taking into account any other payments in the nature of compensation to which the Participant would have a right to receive from the Company and any other person contingent upon the occurrence of
such Change in Control, result in a “parachute payment” as defined under Code Section 280G. 
 SECTION 13. LIMITATIONS ON RIGHTS. 

(a) Retention Rights. Neither the Plan nor any Award granted under the Plan shall be deemed to give any individual a right to remain in
Service as an Employee, Consultant, or Non-Employee Director of the Company, a Parent, a Subsidiary or an Affiliate or to receive any future Awards under the Plan. The Company and its Parents and Subsidiaries and Affiliates reserve the right to
terminate the Service of any person at any time, and for any reason, subject to applicable laws, the Company’s Certificate of Incorporation and Bylaws and a written employment agreement (if any). 

(b) Regulatory Requirements. Any other provision of the Plan notwithstanding, the obligation of the Company to issue Shares or other
securities under the Plan shall be subject to all applicable laws, rules and regulations and such approval by any regulatory body as may be required. The Company reserves the right to restrict, in whole or in part, the delivery of Shares or other
securities pursuant to any Award prior to the satisfaction of all legal requirements relating to the issuance of such Shares or other securities, to their registration, qualification or listing or to an exemption from registration, qualification or
listing. 

  
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 (c) Dissolution. To the extent not previously exercised or settled, all Options, SARs,
Stock Units and unvested Restricted Stock Grants shall terminate immediately prior to the dissolution or liquidation of the Company and shall be forfeited to the Company without consideration (except for repayment of any amounts a Participant had
paid to the Company to acquire unvested Shares underlying the forfeited Awards). 
 SECTION 14. WITHHOLDING TAXES. 

(a) General. A Participant shall make arrangements satisfactory to the Company for the satisfaction of any withholding tax obligations
that arise in connection with his or her Award. The Company shall not be required to issue any Shares or make any cash payment under the Plan until such obligations are satisfied and the Company shall, to the extent permitted by law, have the right
to deduct any such taxes from any payment of any kind otherwise due to the Participant. 
 (b) Share Withholding. The Committee in its
discretion may permit or require a Participant to satisfy all or part of his or her withholding tax obligations by having the Company withhold all or a portion of any Shares that otherwise would be issued to him or her or by surrendering all or a
portion of any Shares that he or she previously acquired (or by stock attestation). Such Shares shall be valued based on the value of the actual trade or, if there is none, the Fair Market Value as of the previous day. Any payment of taxes by
assigning Shares to the Company may be subject to restrictions, including, but not limited to, any restrictions required by rules of the SEC. The Committee may also, in its discretion, permit or require a Participant to satisfy withholding tax
obligations related to an Award through a sale of Shares underlying the Award or, in the case of Options, through Net Exercise or Cashless Exercise. The number of Shares that are withheld from an Award pursuant to this section may also be limited by
the Committee, to the extent necessary, to avoid liability-classification of the Award (or other adverse accounting treatment) under applicable financial accounting rules including without limitation by requiring that no amount may be withheld which
is in excess of minimum statutory withholding rates. The Committee, in its discretion, may permit other forms of payment of applicable tax withholding. 

SECTION 15. DURATION AND AMENDMENTS. 
 (a)
Term of the Plan. The Plan, as set forth herein, is effective on the Adoption Date provided, however, that the Plan is subject to the approval of the Company’s stockholders within one year of the Adoption Date. If the Stockholder
Approval Date does not occur before the first anniversary of the Adoption Date, then the Plan shall terminate as of the first anniversary of the Adoption Date and any Awards granted under the Plan shall also immediately terminate without
consideration to any Award holder. If the stockholders timely approve the Plan, then the Plan shall terminate on the day before the tenth anniversary of the Adoption Date and may be terminated on any earlier date pursuant to this Section 15.
This Plan will not in any way affect outstanding awards that were issued under any other Company equity compensation plans. 

  
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 (b) Right to Amend or Terminate the Plan. The Board may amend or terminate the Plan at any
time and for any reason. No Awards shall be granted under the Plan after the Plan’s termination. An amendment of the Plan shall be subject to the approval of the Company’s stockholders only to the extent required by applicable laws,
regulations or rules. In addition, no such amendment or termination (or amendment of an executed Award Agreement) shall be made which would materially impair the rights of any Participant, without such Participant’s written consent, under any
then-outstanding Award. In the event of any conflict in terms between the Plan and any Award agreement, the terms of the Plan shall prevail and govern. 

SECTION 16. EXECUTION. 
 To record the
adoption of the Plan by the Board, the Company has caused its duly authorized Officer to execute this Plan on behalf of the Company. 
  

			
	SANTA MARIA BIOTHERAPEUTICS, INC.
		
	By:	 	 /s/ Isaac Ciechanover

		
	Name:	 	 Isaac Ciechanover

		
	Title:	 	 President and CEO




  
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