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Reported Tuberculosis in the United States, 2022						Print
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Table 23. Characteristics of Tuberculosis Cases in wgMLSType Clusters1 by Alert Levels Based on Log-Likelihood Ratio (LLR):2 United States, 2020–2022
See surveillance slides #50, #51, #52, #53, and #54.
Table 23. Characteristics of tuberculosis cases in wgMLSType clusters by alert levels based on log-likelihood ratio.
Characteristics
Unique
Clustered
Alert levels for clustered cases3Non-alerted
Medium
High(LLR <4)
(LLR 4 – <10)
(LLR ≥10)No.
(%)
No.
(%)
No.
(%)
No.
(%)
No.
(%)**Total**
**14,695**
**(83.1)**
**2,999**
**(16.9)**
**1,029**
**(34.3)**
**1,238**
**(41.3)**
**732**
**(24.4)****Origin of birth4**U.S-born
2,836
(62.9)
1,673
(37.1)
455
(27.2)
636
(38.0)
582
(34.8)Non-U.S.–born
11,792
(90.0)
1,312
(10.0)
566
(43.1)
597
(45.5)
149
(11.4)Unknown or missing
67
(82.7)
14
(17.3)
8
(57.1)
5
(35.7)
1
(7.1)**Race and ethnicity5**Hispanic or Latino
4,373
(78.0)
1,232
(22.0)
564
(45.8)
469
(38.1)
199
(16.2)American Indian or Alaska Native
78
(37.9)
128
(62.1)
5
(3.9)
22
(17.2)
101
(78.9)Asian
6,188
(95.1)
316
(4.9)
112
(35.4)
191
(60.4)
13
(4.1)Black or African American
2,173
(72.5)
824
(27.5)
196
(23.8)
342
(41.5)
286
(34.7)Native Hawaiian or Other Pacific Islander
117
(45.2)
142
(54.8)
40
(28.2)
58
(40.8)
44
(31.0)White
1,503
(83.4)
300
(16.6)
96
(32.0)
133
(44.3)
71
(23.7)Multiple race
149
(84.2)
28
(15.8)
6
(21.4)
10
(35.7)
12
(42.9)Unknown or missing
114
(79.7)
29
(20.3)
10
(34.5)
13
(44.8)
6
(20.7)**Age group (years)**0–4
55
(34.2)
106
(65.8)
22
(20.8)
57
(53.8)
27
(25.5)5–14
113
(60.1)
75
(39.9)
20
(26.7)
32
(42.7)
23
(30.7)15–24
1,303
(75.7)
419
(24.3)
141
(33.7)
189
(45.1)
89
(21.2)25–44
4,144
(80.0)
1,038
(20.0)
351
(33.8)
436
(42.0)
251
(24.2)45–64
4,391
(81.6)
989
(18.4)
348
(35.2)
379
(38.3)
262
(26.5)≥65
4,689
(92.6)
372
(7.4)
147
(39.5)
145
(39.0)
80
(21.5)**Disease site**Pulmonary only
10,364
(81.5)
2,351
(18.5)
779
(33.1)
1,017
(43.3)
555
(23.6)Extrapulmonary
2,419
(89.6)
281
(10.4)
113
(40.2)
90
(32.0)
78
(27.8)Both
1,902
(83.9)
364
(16.1)
136
(37.4)
130
(35.7)
98
(26.9)Unknown
10
(76.9)
3
(23.1)
1
(33.3)
1
(33.3)
1
(33.3)**Sputum smear**Positive
7,200
(80.5)
1,741
(19.5)
583
(33.5)
751
(43.1)
407
(23.4)Negative
5,815
(86.0)
947
(14.0)
350
(37.0)
361
(38.1)
236
(24.9)Not done
1,537
(83.9)
295
(16.1)
88
(29.8)
120
(40.7)
87
(29.5)Unknown or missing
143
(89.9)
16
(10.1)
8
(50.0)
6
(37.5)
2
(12.5)**Cavitary disease6**Yes
155
(77.9)
44
(22.1)
17
(38.6)
13
(29.5)
14
(31.8)No
1,318
(84.1)
249
(15.9)
94
(37.8)
90
(36.1)
65
(26.1)Unknown or missing
21
(87.5)
3
(12.5)
1
(33.3)
0
(0.0)
2
(66.7)**Homeless within past year**Yes
523
(62.2)
318
(37.8)
114
(35.8)
113
(35.5)
91
(28.6)No
13,988
(84.1)
2,645
(15.9)
898
(34.0)
1,118
(42.3)
629
(23.8)Unknown or missing
184
(83.6)
36
(16.4)
17
(47.2)
7
(19.4)
12
(33.3)**Excess alcohol use within past year**Yes
1,131
(69.0)
509
(31.0)
141
(27.7)
208
(40.9)
160
(31.4)No
13,292
(84.6)
2,422
(15.4)
860
(35.5)
1,004
(41.5)
558
(23.0)Unknown or missing
272
(80.0)
68
(20.0)
28
(41.2)
26
(38.2)
14
(20.6)**Injecting drug use within past year**Yes
96
(51.3)
91
(48.7)
24
(26.4)
33
(36.3)
34
(37.4)No
14,083
(83.4)
2,795
(16.6)
951
(34.0)
1,169
(41.8)
675
(24.2)Unknown or missing
516
(82.0)
113
(18.0)
54
(47.8)
36
(31.9)
23
(20.4)**Noninjecting drug use within past year**Yes
713
(56.1)
559
(43.9)
162
(29.0)
200
(35.8)
197
(35.2)No
13,487
(85.2)
2,336
(14.8)
816
(34.9)
1,004
(43.0)
516
(22.1)Unknown or missing
495
(82.6)
104
(17.4)
51
(49.0)
34
(32.7)
19
(18.3)**Resident of a correctional facility at time of diagnosis**Yes
287
(63.6)
164
(36.4)
41
(25.0)
47
(28.7)
76
(46.3)No
14,301
(83.6)
2,812
(16.4)
972
(34.6)
1,186
(42.2)
654
(23.3)Unknown or missing
107
(82.3)
23
(17.7)
16
(69.6)
5
(21.7)
2
(8.7)**HIV status**Positive
564
(76.9)
169
(23.1)
63
(37.3)
57
(33.7)
49
(29.0)Negative
12,486
(82.7)
2,610
(17.3)
890
(34.1)
1,090
(41.8)
630
(24.1)Refused
287
(91.1)
28
(8.9)
9
(32.1)
16
(57.1)
3
(10.7)Not offered
774
(86.8)
118
(13.2)
46
(39.0)
44
(37.3)
28
(23.7)Unknown, missing or indeterminate
584
(88.8)
74
(11.2)
21
(28.4)
31
(41.9)
22
(29.7)**Multidrug-resistant TB**Yes
192
(88.9)
24
(11.1)
4
(16.7)
13
(54.2)
7
(29.2)No
14,026
(82.9)
2,898
(17.1)
996
(34.4)
1,194
(41.2)
708
(24.4)Unknown or missing
477
(86.1)
77
(13.9)
29
(37.7)
31
(40.3)
17
(22.1)1wgMLSType clusters have two or more cases with matching wgMLSType within a county during the specified 3-year time period.2Alert levels are based on a log-likelihood ratio, which calculates the geographical concentration of a genotype in a county compared to the rest of the country during a 3-year period.3There were 2,999 cases in 987 clusters: 732 cases were in 78 (7.9%) high alert clusters; 1,238 cases were in 476 (48.2%) medium alert clusters, and 1,029 cases were in 433 (43.9%) non-alert clusters.4Persons born in the United States, certain U.S. territories, or elsewhere to at least one U.S. citizen parent are categorized as U.S.-born. All other persons are categorized as non-U.S.–born.5Persons who identified as Hispanic or Latino were categorized as “Hispanic,” regardless of self-reported race. Persons who did not identify as Hispanic or Latino were categorized by self-reported race; if more than one race was reported, the person was categorized as “Multiple race.”6Cavitary disease only assessed for persons with pulmonary TB and an abnormal x-ray.
**Note:**
Data for all years are updated through July 8, 2023.Table Printing Tips
							
					
							Last Reviewed:  November 15, 2023						Source: 	Division of Tuberculosis Elimination, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention
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