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Reported Tuberculosis in the United States, 2017										Related Pages
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Table 10. Percentages of Tuberculosis Cases, by Initial Drug Regimen, Use of Directly Observed Therapy (DOT), and Completion of Therapy (COT): United States, 1993–2017
Table 10. Percentages of Tuberculosis Cases, by Initial Drug Regimen, Use of Directly Observed Therapy (DOT), and Completion of Therapy (COT): United States, 1993–2017
Year
Initial Drug Regimen1,2
Directly Observed Therapy3
Therapy <1 Year Indicated4IRZE
Multi 4+ Drug Regimen5
DOT Only
Both DOT and Self-Administered
COT <1 Year
COT Ever1993
(40.3)
(4.9)
(21.7)
(14.4)
(63.4)
(86.0)1994
(55.7)
(5.5)
(28.1)
(20.5)
(68.6)
(86.8)1995
(62.7)
(4.8)
(37.3)
(21.5)
(74.1)
(89.2)1996
(67.3)
(4.4)
(42.5)
(22.4)
(76.8)
(90.2)1997
(71.9)
(4.3)
(47.0)
(23.8)
(78.7)
(91.0)1998
(74.3)
(4.3)
(47.7)
(26.6)
(81.2)
(92.2)1999
(76.9)
(4.7)
(49.4)
(27.6)
(81.4)
(92.2)2000
(78.5)
(4.2)
(52.5)
(25.8)
(82.2)
(92.5)2001
(79.8)
(3.9)
(53.6)
(27.5)
(82.5)
(92.7)2002
(80.3)
(4.3)
(55.4)
(27.8)
(83.0)
(92.5)2003
(81.3)
(4.7)
(56.5)
(28.5)
(83.6)
(92.8)2004
(82.4)
(4.9)
(58.9)
(27.7)
(84.3)
(92.6)2005
(83.7)
(5.0)
(57.9)
(29.6)
(84.0)
(92.5)2006
(83.3)
(6.6)
(57.5)
(30.4)
(84.8)
(93.2)2007
(83.8)
(6.5)
(56.3)
(32.9)
(85.6)
(93.9)2008
(84.2)
(7.6)
(56.4)
(33.5)
(86.1)
(93.3)2009
(84.3)
(7.8)
(59.6)
(30.3)
(88.8)
(95.6)2010
(84.5)
(8.1)
(59.3)
(31.0)
(89.6)
(96.1)20116
(85.2)
(8.1)
(62.2)
(29.2)
(89.7)
(96.4)20126
(85.4)
(9.0)
(61.8)
(29.1)
(90.1)
(96.4)20136
(84.6)
(9.6)
(63.2)
(28.9)
(89.9)
(96.3)20146
(85.3)
(9.1)
(63.8)
(29.1)
(90.2)
(96.8)20156
(85.3)
(9.2)
(65.1)
(28.5)
(89.5)
(95.8)20166
(85.1)
(10.1)
—
—
—
—20176
(83.2)
(10.2)
—
—
—
—1Includes persons alive at diagnosis.2I, isoniazid; R, rifampin; Z, pyrazinamide; E, ethambutol. Excludes cases with no information on initial drug regimen. In 2017, 1.3% received no initial drug therapy and 0.1% were started on one drug.3Includes persons alive at diagnosis with initial drug regimen of one or more drugs prescribed.4Therapy <1 year indicated in persons alive at diagnosis with an initial drug regimen of one or more drugs prescribed, and who did not die within one year of initiating therapy. Persons with initial isolate rifampin resistant, or patient with bone and joint disease, meningeal disease or disease of the central nervous system, or pediatric patient (age <15) with miliary disease or positive blood culture or a positive nucleic acid amplification test on a blood specimen, and those who moved out of the country within one year of initiating treatment were excluded.5Indicates at least a four drug regimen that is not IRZE only6Beginning in 2011, those who moved out of the country during treatment are excluded from the denominator of those eligible for COT.**Note:** Data as of June 1, 2018.
See Technical Notes for details and for description of COT calculation.
							
					
						Page last reviewed:  October 22, 2018					Content source: 	Division of Tuberculosis Elimination, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention homeTuberculosisBasic TB Factsplus iconHow TB SpreadsLatent TB Infection and TB DiseaseSigns & SymptomsTB Risk FactorsExposure to TBTB PreventionVaccinesTB & HIV CoinfectionTB and DiabetesTB TermsPersonal StoriesTesting & Diagnosisplus iconWho Should be TestedTesting for TB InfectionTesting in BCG-Vaccinated PersonsTB Screening and Testing of Health Care PersonnelTesting During PregnancyDiagnosing latent TB infection and TB diseaseTreatmentplus iconDeciding When to Treat Latent TB InfectionTreatment Regimens for Latent TB Infection (LTBI)Treatment for TB DiseaseAdverse EventsTB Treatment of Persons Living with HIVTB Treatment and PregnancyTB Treatment for ChildrenFrequently Asked QuestionsDrug-Resistant TBResearchplus iconTB Epidemiologic Studies Consortiumplus iconResearch ProjectsPublicationsTB Trials Consortiumplus iconStudy DescriptionsBackgroundBehavioral & Social Science ResearchHealth Care Settingsplus iconTB Infection Control in Health Care SettingsResources for TB Screening and Testing of Health Care Personnelplus iconFrequently Asked QuestionsTB in Specific Populationsplus iconHealth DisparitiesAsian PersonsBlack or African American PersonsHispanic or Latino PersonsChildrenPregnancyCorrectional FacilitiesPeople Experiencing HomelessnessInternational TravelersLaboratory Informationplus iconDrug Susceptibility TestingFalse-Positive Investigation ToolkitInterim Laboratory Biosafety Guidance for XDR  tuberculosis strainsModel Performance Evaluation Program (MPEP)Rapid Molecular Testing to Detect Drug-Resistant TB in the USplus iconExecutive SummaryIntroductionBackground on Tests for Molecular Detection of DRGeneral Considerations and Principles for a Molecular DR Testing ServicePossible Scenarios and Scope of Testing for a Molecular DR Testing ServiceResearch NeedsGeneral Recommendations of the Expert PanelCommunication Plan for the ReportRecommendationsReferencesPanel Members and CDC ParticipantsAppendix 1Appendix 2Appendix 3The Uses of Nucleic Acid Amplification Tests for the Diagnosis of TBplus iconGeneral ConsiderationsGeneral Recommendations of the Expert PanelRecommendations to ACET, CDC, DTBEData & Statisticsplus iconTB Incidence in the United StatesReported TB in the US, 2022 Surveillance Reportplus iconNational DataReporting Area DataRisk FactorsDemographicsTB Treatment and Case OutcomesDrug-Resistant TBMolecular SurveillanceTuberculosis in the United States, 2022 (Slide Set)Archived Surveillance Reports and Slide Sets2021 State and City ReportArchived State and City ReportsProfessional Resources & Toolsplus iconTools for Healthcare ProvidersResources for TB Programsplus iconStrengthening Civil Surgeons’ Capacity to Improve LTBI Surveillance and Outcomes Among Status AdjustersNotice of Funding Opportunity (NOFO)Program EvaluationTB Centers of ExcellenceTB Elimination AllianceTB Genotypingplus iconConventional TB GenotypingWhole Genome SequencingTB GIMSAnalytic ToolsLatent Tuberculosis Infection ResourcesPublications & Productsplus iconPatient and Public MaterialsFact SheetsGuidelinesplus iconControl & EliminationDrug-Resistant TBInfection Control & PreventionLaboratory & GenotypingTB & HIVTB in Specific PopulationsTesting & DiagnosisTreatmentVaccines & ImmunizationsArchived TB GuidelinesGuides & Toolkitsplus iconAggregate ReportsCDC TB Surveillance TrainingCore CurriculumEffective TB Interviewing for Contact InvestigationEthnographic GuidesFalse-Positive Investigation ToolkitForging Partnerships to Eliminate TuberculosisGuide to Application of GenotypingLTBI: A Guide for Primary Health Care ProvidersMantoux Tuberculin Skin Testing ProductsReport of Verified Case of Tuberculosis (RVCT)Self-Study ModulesTB Contact Investigation Interviewing Skills CourseTB eDOT ToolkitUnderstanding the TB Cohort Review ProcessNewslettersplus iconTB Notes, No. 4, 2023TB Notes, No. 3, 2023TB Notes. No. 2, 2023TB Notes. No. 1, 2023TB Notes, No. 4, 2022TB Notes, No. 3, 2022TB Notes, No. 2, 2022TB Notes, No. 1, 2022TB Notes, No. 4, 2021TB Notes, No. 3, 2021TB Notes, No. 2, 2021TB Notes, No. 1, 2021Pamphlets, Brochures, Bookletsplus iconQuestions and AnswersPatient Education SeriesTuberculosis - Get the FactsTuberculosis - The Connection between TB and HIV12-Dose Regimen for Latent TB Infection-Patient Education BrochurePostersplus iconMantoux Tuberculin Skin Test Wall ChartWorld TB DayThink TBStop TBTake on TBReports & Articlesplus iconDTBE Authored Journal ArticlesTuberculosis Laboratory Aggregate ReportsSlide Setsplus iconIntroduction to TuberculosisEpidemiology of Tuberculosis Among Non-U.S.​–Born Persons in the United States, 1993–2016Self-Study Modules on Tuberculosis, 1-5 Slide SetsThe Tuberculosis (TB) in Correctional Settingsplus iconFacilitator GuideIntroduction to TB GenotypingEpidemiology of Tuberculosis in Correctional Facilities, United States, 1993-2017Prevention and Control of Tuberculosis in Correctional and Detention FacilitiesGuidelines for Preventing the Transmission of M. TB in Health care SettingsInvestigation of Contacts of Persons with Infectious TBEpidemiology of Pediatric Tuberculosis in the United StatesTargeted Tuberculosis Testing and Treatment of Latent Tuberculosis InfectionElectronic Tools & ResourcesWeb-Based Courses & Webinarsplus iconTB 101 for Health Care WorkersContent SyndicationInfographicsplus iconSocial Media GraphicsCustomizable Take on TB Infographic with InstructionsEventsWorld TB Dayplus iconU.S. TB ChampionsHistoryFeaturesplus iconTB Risk FactorsTreating Latent TB Infection with Short-Course RegimensWorld Tuberculosis (TB) Day 2021World Tuberculosis (TB) Day 2020Linksplus iconState TB Control OfficesAbout Usplus iconMission Statement and Activitiesplus iconDTBE Strategic PlanNational TB Program ObjectivesOrganization ChartAdvisory Groupsplus iconFederal TB Task Force To receive email updates about this page, enter your email address: Email Address			What's this?				Submit


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