CDC-RFA-TO-23-0001 Overview: 

Strengthening Public Health Systems and Services in Indian Country

CDC has announced a new five-year cooperative agreement for eligible American Indian and Alaska 

Native (AI/AN) federally recognized Tribes and regional tribally designated organizations. This program

will strengthen the quality, performance, and infrastructure of tribal public health systems, including 

workforce, data and information systems, and programs and services. 

Program Outcomes

Throughout the period of performance recipients will work towards achieving at least one of the following 

outcomes:

• Improved capacity to develop public health programs and services to address prioritized

public health activities in AI/AN communities.

• Improved capacity to implement public health programs and services to address prioritized

public health activities in AI/AN communities.

• Improved capacity to evaluate public health programs and services to address prioritized

public health activities in AI/AN communities.

Program Strategies

Recipients will address up to two of the following strategies:

• Foundational Public Health Capabilities implemented to strengthen the ability to conduct

assessment/surveillance, prepare for and respond to public health emergencies; develop and

support policies, communications, community partnership, organizational competencies, and

accountability and performance management.

• Data Modernization activities to develop and deploy scalable, flexible, and sustainable

technologies, policies, and methods to implement data and analytical capabilities to support

the Essential Public Health Services.

• Public Health Programs and Services implemented to strengthen the ability to

comprehensively meet tribal public health needs.

• Workforce activities to develop and maintain a diverse workforce with cross-cutting skills and

competencies.

Funding

This funding opportunity includes a two-part strategy.

Funding Strategy 1: Initial Funding

Responsive applications submitted under this funding opportunity will be reviewed objectively as 

described in the Review and Selection Process section of this NOFO. Awards under Funding 

Strategy 1 will support strengthening tribal public health systems and services. 
Applicants selected for Funding Strategy 1 will become part of a group of organizations that are 

eligible for funding under Funding Strategy 2.

Funding Strategy 2: CDC Centers, Institute, and Offices (CIO) Project Plans

The second funding strategy is subject to the availability of appropriated funds and agency priorities. To 

maximize CDC's program priorities and health system needs in Indian Country, applicants funded under

Funding Strategy 1 will be eligible to apply for additional funding under Funding Strategy 2. Under 

Funding Strategy 2, CDC will publish and compete CIO project plans according to entity type, HHS 

region, and/or IHS area.

Key Dates

• April 5, 2023: NOFO published on Grants.gov

• April 11 and 13, 2023: Applicant informational calls

• May 5, 2023: Optional letters of Intent (LOI) due from applicants

• June 6, 2023: Applications due by 11:59 PM EDT.

• August 1, 2023: Anticipated notices of award (NOA) issued

• August 31, 2023: Anticipated Budget period start date

o Budget period length: 12 months (August 31–August 30)

o Period of Performance: 5 years (August 31, 2023–August 30, 2028)

For More Information 

Email tribalcoag@cdc.gov or visit Strengthening Public Health Systems and Services in Indian Country.