Support Documents for 

Significant New Use Rule (SNUR) on 

Premanufacture Notice (PMN) 

P-10-361 

EPA Docket EPA-HQ-OPPT-2011-0577 

 

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Index 

A-001 Structure Activity Team (SAT) Report for 

 PMN P-10-361 

A-002 Initial Review Engineering Report for 

 PMN P-10-361 

A-003 Initial Review Exposure Report for 

 PMN P-10-361 

 

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A-001 

Structure Activity Team (SAT) Report 

 for PMN P-10-361 

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A-002 

Initial Review Engineering Report 

 for PMN P-10-361 

 

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Support - P-10-0361 engineering.2.txt

INITIAL REVIEW ENGINEERING REPORT 

PMN: 10-0361

Post-Focus Draft Revision 1 3/24/2011

ENGINEER: Austin \ AH

PV (kg/yr): 

Revision Notes / Assessment Overview: 

 

 

 

 

SUBMITTER: 

USE: 

OTHER USES: 

 

 

MSDS: Yes Label: No

Gen Eqpt:

Respirator:

Health Effects:

TLV/PEL:

CRSS :

Chemical Name: 

S-H20: 0.1094 g/L @

VP: 8.5E-3 torr @

MW: 164.00 %<500 %<1000

Physical State and Misc CRSS Info:

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Support - P-10-0361 engineering.2.txt

Neat: Solid Mfg: Proc/Form: End Use: 

Submitted data: off-white solid; MP = 70 °C; BP = 250 °C

at 745 torr; WS = 0.255 g/L (est.); VP = 0.00776 torr

(est.); flash point >65.6 °C. Literature data (STN eprop

database): MP = 70 °C; BP = 250-250.5 °C at 745 torr,

132-134 °C at 15 torr. NOMO5 (Class 5) estimated data

from BP = 250 °C at 745 torr: BP = 250.7 °C, VP = 0.0085

torr. EPI estimated data (input MP = 70 °C): BP = 254.6

°C; VP = 0.00324 torr; WS = 0.1094 g/L; log P = 4.06. ACD

Labs estimated data (STN pprop database): BP = 250.9 °C;

VP = 1.33E-02 torr; WS = 0.33 g/L; log P = 3.741.

Consumer Use: No

SAT (concerns) (05/11/2010):

Migration to groundwater: Moderate

PBT rating: P1B1T2

Health: 2 Dermal, Drinking Water, Inhalation

Eco: 3 Water (All releases to water with a CC = 1ppb), 

OCCUPATIONAL EXPOSURE RATING: 2-3A

NOTES & KEY ASSUMPTIONS:

Generated by the 06/07/2005 version of ChemSTEER. 

 

POLLUTION PREVENTION CONSIDERATIONS:

P2 Claim: 

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Support - P-10-0361 engineering.2.txt

.

EXPOSURE-BASED REVIEW: 

INITIAL REVIEW ENGINEERING REPORT 

PMN: 10-0361

Manufacturing

Number of Sites/ Location: 

 Days/yr: 

Basis:

Process Description:

ENVIRONMENTAL RELEASES ESTIMATE SUMMARY

IRER Note: The daily releases listed for any source below

may coincide with daily releases from the other sources

to the same medium.

Output 2: 

to: 

from: 

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Support - P-10-0361 engineering.2.txt

basis:

Output 2: 

to: 

from:

basis: 

Typical: 

Worst Case: 

to: 

from: 

basis: 

Typical: 

Worst Case: 

to: 

from: 

basis: 

Output 2: 

to: 

from:

basis:

Output 2: 

to: 

from: 

basis:

RELEASE TOTAL

OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY

Tot. # of workers exposed via assessed routes: 

Basis:

Inhalation:

Exposure to 

Upper Bound: 

Number of workers (all sites) with inhalation exposure: 

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Basis:

INHALATION MONITORING DATA REVIEW

1) Uncertainty (estimate based on model, regulatory limit

 or data not specific to industry): Yes

2)a) Exposure level > 1 mg/day? Yes

 OR

 b) Hazard Rating for health of 2 or greater? 2 Yes

Inhalation Monitoring Data Desired? Yes (both criteria

met)

Exposure to 

Typical: 

Worst Case: 

Number of workers (all sites) with inhalation exposure: 

Basis:

INHALATION MONITORING DATA REVIEW

1) Uncertainty (estimate based on model, regulatory limit

 or data not specific to industry): Yes

2)a) Exposure level > 1 mg/day? No

 OR

 b) Hazard Rating for health of 2 or greater? 2 Yes

Inhalation Monitoring Data Desired? Yes (both criteria

met)

Dermal:

Exposure to 

High End: 

Number of workers (all sites) with dermal exposure: 

Basis:

Exposure to 

High End: 

Number of workers (all sites) with dermal exposure: 

Basis:

INITIAL REVIEW ENGINEERING REPORT 

PMN: 10-0361

Use: 

Number of Sites/ Location: 

Days/yr: 

Basis:

Process Description:

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Support - P-10-0361 engineering.2.txt

ENVIRONMENTAL RELEASES ESTIMATE SUMMARY

IRER Note: The daily releases listed for any source below

may coincide with daily releases from the other sources

to the same medium.

Output 2: 

to: 

from: 

basis:

Typical: 

Worst Case: 

to: 

from: 

basis: 

Output 2: 

to: 

from:

basis: 

Typical: 

Worst Case: 

to: 

from: 

basis: 

Conservative: 

to: 

from:

basis: 

Output 2: 

to: 

from: 

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basis:

Incineration

Output 2: 

to: 

from: 

basis:

RELEASE TOTAL

OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY

Tot. # of workers exposed via assessed routes: 

Basis:

Inhalation:

Exposure to 

Upper Bound: 

Number of workers (all sites) with inhalation exposure: 

Basis:

INHALATION MONITORING DATA REVIEW

1) Uncertainty (estimate based on model, regulatory limit

 or data not specific to industry): Yes

2)a) Exposure level > 1 mg/day? Yes

 OR

 b) Hazard Rating for health of 2 or greater? 2 Yes

Inhalation Monitoring Data Desired? Yes (both criteria

met)

Exposure to 

Typical: 

Worst Case: 

Number of workers (all sites) with inhalation exposure: 

Basis:

INHALATION MONITORING DATA REVIEW

1) Uncertainty (estimate based on model, regulatory limit

 or data not specific to industry): Yes

2)a) Exposure level > 1 mg/day? No

 OR

 b) Hazard Rating for health of 2 or greater? 2 Yes

Inhalation Monitoring Data Desired? Yes (both criteria

met)

Dermal:

Exposure to 

High End: 

Number of workers (all sites) with dermal exposure: 

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Basis:

Exposure to 

High End: 

Number of workers (all sites) with dermal exposure: 

Basis:

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A-003 

Initial Review Exposure Report 

 for PMN P-10-361 

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Date 3/25/11 Page of 

POST FOCUS EXPOSURE REPORT 

Summary Page 

Chemical ID: P-10-0361 Reviewer: bevington 

Endpoints-Assessed Table 

Reasons for not assessing releases 

Endpoints/Assessment 

Cycles1

Releases 

Assessed 

in 

NCEM2? 

No XB 

Testing 

Required 

No 

Hazard 

Concern 

No 

Releases 

Release 

Below 

Acute 

Threshold5

Release 

Below 

Chronic 

Threshold5

Other 

Ingestion 

 Surface water 

 Ground water (landfill) 

 Consumer Use: DtD2

Inhalation 

 Air: incineration (stack) 

 Air: fugitive 

 Consumer Use: CEM3

Dermal 

 Consumer Use: CEM 

Eco 

 Surface water: ADR 

conc and/or PDM4

 Consumer Use: DtD

1

Assessment cycles are endpoint concentrations and dose calculations within the NCEM2 model. 2

Down-the-Drain 

3

Consumer Exposure Model 

4

Probabilistic Dilution Model 

5

The threshold values for assessing endpoints are 1 mg/day for acute doses and 1 mg/year for chronic doses. 

EAB DROP: Release information for this compound does not meet criteria for preparation of an exposure 

assessment in the Exposure Assessment Branch=s (EAB) Initial Review Exposure Report (this report). 

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