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ACRONYMS AND ABBREVIATIONS

BPPD The EPA’s Biopesticides and Pollution Prevention Division 

CFR Code of Federal Regulations 

DCI Data Call-In 

EDSP Endocrine Disruptor Screening Program 

EPA U.S. Environmental Protection Agency 

FFDCA Federal Food, Drug, and Cosmetic Act 

FIFRA Federal Insecticide, Fungicide, and Rodenticide Act 

FQPA Food Quality Protection Act 

FR Federal Register 

FWP Final Work Plan 

IDS Incident Data System 

MRID No. Master Record Identification Number: The EPA's system of recording and tracking studies submitted to the 

Office of Pesticide Programs. 

MRL Maximum Residue Limit 

OPP The EPA’s Office of Pesticide Programs 

PC Code Pesticide chemical code: a six-digit number assigned by OPP to identify pesticide chemicals. 

PMRA Health Canada’s Pest Management Regulatory Agency 

PWP Preliminary Work Plan 

TGAI Technical grade of the active ingredient 

TMDL Total Maximum Daily Load 

US United States 
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I. PRELIMINARY WORK PLAN 

A. Overview 

The docket for Sucrose (Case 5117) is now open, initiating the first public comment period for this 

Registration Review case (docket number EPA-HQ-OPP-2013-0751). Sucrose is currently registered in 

one product for use as an insect bait in a trap for controlling flies in an outdoor setting. This Preliminary 

Work Plan (PWP) explains what the U.S. Environmental Protection Agency’s (EPA) Office of Pesticide 

Programs knows about sucrose, highlights its anticipated data and assessment needs, identifies types of 

information that would be especially useful in conducting the review, and provides an anticipated 

timeline for completing the Registration Review process for sucrose. 

The Registration Review process was designed to include a public participation component and by 

sharing this information in the docket, EPA intends to inform the public of what it knows about sucrose 

and what types of new data or other information would be helpful to receive as it moves toward a 

decision on sucrose. The EPA encourages all interested stakeholders to review the PWP and to provide 

comments and additional information that will help the EPA’s decision-making process for this 

biochemical pesticide. Interested stakeholders could include the following: environmental nonprofit or 

interest groups; pesticide manufacturers; agricultural labor or commodity groups; commercial, 

institutional, residential, and other users of pesticides; or the public at large. In addition to general areas 

on which persons may wish to comment, there are some areas identified in the PWP about which the 

EPA specifically seeks comments and information. 

The PWP begins by describing the statutory and regulatory authorities for Registration Review. Next, it 

provides background on sucrose, which includes a description of its mode of action, the currently 

registered pesticide product, application rates and methods, use sites, and tolerance exemption 

information. Then, it lists the anticipated data needs, risk assessments, and a projected Registration 

Review timeline for this case. Finally, the PWP provides guidance for commenters, explains the next 

steps EPA will be taking, summarizes background information, and lists supporting studies, risk 

assessments, and other documents available for the Registration Review of sucrose. 

Further information about this case, including background and supporting documents, is available at 

http://www.regulations.gov (under “SEARCH for: Rules, Comments, Adjudications or Supporting 

Documents,” enter the docket identification number, which is indicated above). 

B. Statutory and Regulatory Authority

The Food Quality Protection Act (FQPA) of 1996 mandated a Registration Review program. All 

pesticides distributed or sold in the United States (US) must generally be registered by the EPA, based 

on scientific data showing that they will not cause unreasonable risks to human health or the 

environment when used as directed on the product labeling. The Registration Review program is 

intended to make sure that, as the ability to assess risk evolves and as policies and practices change, all 

registered pesticides continue to meet the statutory standard of no unreasonable adverse effects to human 

health or the environment. Changes in science, public policy, and pesticide use practices will occur over 

time. Through the Registration Review program, the EPA periodically reevaluates pesticides to make 
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sure that, as change occurs, products in the marketplace can continue to be used safely. Information on 

this program is provided on the EPA’s website.1

 

 

The EPA is implementing the Registration Review program pursuant to Federal Insecticide, Fungicide, 

and Rodenticide Act (FIFRA) section 3(g) and will review each registered pesticide every 15 years to 

determine whether it continues to meet the FIFRA standard for registration. The regulations governing 

Registration Review begin at 40 C.F.R. § 155.40. The EPA will consider benefits information and data as 

required by FIFRA. The public phase of Registration Review begins when the initial docket is opened 

for each case. The docket is the EPA’s opportunity to state what it knows about the pesticide and what 

additional risk analyses and data or information it believes are needed to make a Registration Review 

decision. After reviewing and responding to comments and data received in the docket during this initial 

comment period, the EPA will develop a Final Work Plan (FWP) and the anticipated schedule for the 

Registration Review of Sucrose. 

 C. Background and Regulatory Information 

i. Summary of the Active Ingredient, Usage and the Associated Pesticide Product 

Sucrose, also known as common table sugar, is registered as a biochemical pesticide for use as an insect 

bait. EPA has no available usage data for sucrose, likely due to its non-agricultural use pattern. 

On June 2, 2009, the EPA registered Bull Run Fly Attractant as a fly trap for outdoor use. Bull Run Fly 

Attractant is the only currently registered pesticide product containing sucrose as an active ingredient. 

Through use of the currently registered product containing sucrose as an active ingredient, it is intended 

that flies be attracted into a bag filled with the sucrose solution where they eventually die as a result of 

drowning. The bag is made of plastic and designed to allow flies to enter through a small opening at the 

top. The product is intended to be hung in outdoor areas where flies congregate. Further information 

regarding this product appears in Table 2, below. 

Table 1 provides a summary of the chemical facts for Sucrose. 

Table 1. Chemical Facts for Sucrose 

PC code 000023 

Case Number 5117 

CAS Number 57-50-1 

Year first registered 2009 

Pesticide Type Bait 

Chemical class Biochemical 

Reregistration Eligibility 

Decision (RED) 

Not applicable. Because it was registered after November 1984, sucrose was not 

subject to reregistration. 

Tolerance Reassessment 

Eligibility Decision (TRED) 

Not applicable. 

Cumulative group Not applicable. Sucrose has not been identified as a member of a cumulative 

group that shares a common mechanism of toxicity. 

40 CFR Citation This chemical falls under the exemption from a requirement of a tolerance 

established at 40 CFR § 180.950, Tolerance exemption for minimal risk active 

and inert ingredients. 

Non-pesticidal uses Commonly consumed food ingredient. 

 

1

 See http://www.epa.gov/oppsrrd1/registration_review/. 
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TABLE 2. Information About the Currently Registered Sucrose Pesticide Product 

EPA 

Registration 

Number 

Product Name 

(% Active Ingredient; 

Formulation Type)

Date 

Registered Application Rates Application Methods Use Sites 

84565-2 

Bull Run Fly Attractant 

(42.1% Sucrose; dry 

formulation, user adds 

water) 

June 2, 2009 

1 trap per infested 

area (area not 

specified) - trap will 

catch up to 20,000 

flies 

Hanging trap 

Outdoor 

lawn/garden/farm 

use (compost piles, 

garbage area, 

stables, etc) 

ii. Tolerance Actions

Currently, there are no registered products for food use that contain sucrose. However, sucrose is exempt 

from the requirement of a tolerance as follows: 

40 C.F.R. § 180.950 Tolerance exemptions for minimal risk active and inert ingredients

Unless specifically excluded, residues resulting from the use of the following substances as either an 

inert or an active ingredient in a pesticide chemical formulation, including antimicrobial pesticide 

chemicals, are exempted from the requirement of a tolerance under FFDCA section 408, if such use is in 

accordance with good agricultural or manufacturing practices. 

(a) Commonly consumed food commodities. Commonly consumed food commodities means foods 

that are commonly consumed for their nutrient properties. The term commonly consumed food 

commodities shall only apply to food commodities (whether a raw agricultural commodity or a 

processed commodity) in the form the commodity is sold or distributed to the public for consumption. 

(1) Included within the term commonly consumed food commodities are: 

(i) Sugars such as sucrose, lactose, dextrose and fructose, and invert sugar and syrup. 

(ii) Spices such as cinnamon, cloves, and red pepper. 

(iii) Herbs such as basil, anise, or fenugreek. 

(2) Excluded from the term commonly consumed food commodities are: 

(i) Any food commodity that is adulterated under 21 U.S.C. 342. 

(ii) Both the raw and processed forms of peanuts, tree nuts, milk, soybeans, eggs, fish, crustacea, 

and wheat. 
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(iii) Alcoholic beverages. 

(iv) Dietary supplements. 

(b) Animal feed items. Animal feed items means meat meal and all items derived from field crops 

that are fed to livestock excluding both the raw and processed forms of peanuts, tree nuts, milk, 

soybeans, eggs, fish, crustacea, and wheat. Meat meal is an animal feed composed of dried animal fat 

and protein that has been sterilized. Other than meat meal, the term animal feed item does not extend to 

any item designed to be fed to animals that contains, to any extent, components of animals. Included 

within the term animal feed items are: 

(1) The hulls and shells of the commodities specified in paragraph (a)(2)(ii) of this section, and 

cocoa bean. 

(2) Bird feed such as canary seed. 

(3) Any feed component of a medicated feed meeting the definition of an animal feed item. 

(c) Edible fats and oils. Edible fats and oils means all edible (food or feed) fats and oils, derived 

from either plants or animals, whether or not commonly consumed, including products derived from 

hydrogenating (food or feed) oils, or liquefying (food or feed) fats. 

(1) Included within the term edible fats and oils are oils (such as soybean oil) that are derived from 

the commodities specified in paragraph (a)(2)(ii) of this section when such oils are highly refined via a 

solvent extraction procedure. 

(2) Excluded from the term edible fats and oils are plant oils used in the pesticide chemical 

formulation specifically to impart their characteristic fragrance and/or flavoring. 

(d) [Reserved] 

(e) Specific chemical substances. Residues resulting from the use of the following substances [See

40 CFR § 180.950 for table] as either an inert or an active ingredient in a pesticide chemical 

formulation, including antimicrobial pesticide chemicals, are exempted from the requirement of a 

tolerance under FFDCA section 408, if such use is in accordance with good agricultural or 

manufacturing practices. 

Federal Register Citation – Final Rule (67 FR 36534, May 24, 2002) 

D. Anticipated Data Needs and Risk Assessments 

Provided below are tables of the current data requirements for biochemical pesticides as set forth in 40 

CFR § 158, subpart U. They are arrayed by scientific discipline (i.e., product chemistry, human health 

assessment, and nontarget organisms and environmental fate) and descriptions are included regarding 

how the data requirements have been fulfilled or where data have been waived. At this time, no data 

gaps (anticipated data needs) for sucrose have been identified. The most recent comprehensive risk 

assessment for sucrose was completed September 20, 2008, in support of the first biochemical 
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registration of sucrose, which occurred on June 2, 2009 (U.S. EPA, 2008). Because there are no data 

gaps for sucrose and no additional information has been received on this biochemical since it was first 

registered, the Agency does not anticipate the need to conduct a new risk assessment during registration 

review.

i. Product Analysis (40 C.F.R. § 158.2030) 

TABLE 2. Summary of Product Analysis Data for Sucrose 

Harmonized 

Guideline 

Number 

Data Requirement 

Has Data 

Requirement Been 

Addressed? How? 

Source MRID No. 

880.1100 Product Identity and Composition Yes – Study U.S. EPA (2008) 473969-22 

880.1200 Description of Staring Materials, 

Production, and Formulation Process Yes – Study U.S. EPA (2008) 473969-22 

880.1400 Discussion of Formation of Impurities Yes – Study U.S. EPA (2008) 473969-22 

830.1700 Preliminary Analysis Yes – Study U.S. EPA (2008) 473969-22 

830.1750 Certified Limits Yes – Study U.S. EPA (2008) 473969-22 

830.1800 Enforcement Analytical Method Yes – Study U.S. EPA (2008) 473969-22 

TABLE 3. Summary of Physical and Chemical Characteristics for Sucrose 

Harmonized 

Guideline 

Number 

Data Requirement 

Has Data 

Requirement Been 

Addressed? How? 

Source MRID No. 

830.6302 Color Yes – Study U.S. EPA (2008) 473969-23 

830.6303 Physical State Yes – Study U.S. EPA (2008) 473969-23 

830.6304 Odor Yes – Study U.S. EPA (2008) 473969-23 

830.6313 Stability to Normal and Elevated 

Temperatures, Metals and Metal Ions Yes – Study U.S. EPA (2008) 473969-23 

830.6315 Flammability Not applicable; data are not required for technical grade active 

ingredients. 

830.6317 Storage Stability Not applicable; data are not required for technical grade active 

ingredients. 

830.6319 Miscibility Not applicable; data are not required for technical grade active 

ingredients. 

830.6320 Corrosion Characteristics Not applicable; data are not required for technical grade active 

ingredients. 

830.7000 pH Yes – Study U.S. EPA (2008) 473969-24 

830.7050 UV/Visible Light Absorption Not applicable to the TGAI test substance.1

830.7100 Viscosity Not applicable; data are not required for technical grade active 

ingredients. 

830.7200 Melting Point/Melting Range Yes – Study U.S. EPA (2008) 473969-23 

830.7220 Boiling Point/Boiling Range Not applicable to the TGAI test substance.2

830.7300 Density/Relative Density/Bulk Density 

(Specific Gravity) Yes – Study U.S. EPA (2008) 473969-23 
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TABLE 3. Summary of Physical and Chemical Characteristics for Sucrose 

Harmonized 

Guideline 

Number 

Data Requirement 

Has Data 

Requirement Been 

Addressed? How? 

Source MRID No. 

830.7520 Particle Size, Fiber Length, and Diameter 

Distribution Not applicable to the TGAI test substance.3

830.7550 

830.7560 

830.7570

Partition Coefficient (n-Octanol Water) Yes – Study U.S. EPA (2008) 473969-23 

830.7840 Water Solubility Yes – Study U.S. EPA (2008) 473969-23 

830.7950 Vapor Pressure Yes – Study U.S. EPA (2008) 473969-23 

1

 UV/Visible Light Absorption data are not applicable because sucrose is white and sucrose solutions are colorless; therefore, sucrose does 

not absorb visible light. 

2

 Boiling point data are not applicable because sucrose is a solid at room temperature. 3

 Particle size, fiber length, and diameter distribution data is not applicable because sucrose is not water insoluble or fibrous (with diameter 

≥0.1 μm). 

ii. Human Health Assessment (40 C.F.R. § 158.2050) 

TABLE 4. Summary of Human Health Assessment Data for Sucrose 

Harmonized 

Guideline 

Number 

Data Requirement 

Has Data 

Requirement Been 

Addressed? How? 

Source 

MRID No. or 

Other 

Reference 

870.1100 Acute Oral Toxicity - Rat Yes – Data Waiver U.S EPA (2008) 473969-27 

870.1200 Acute Dermal Toxicity Yes – Data Waiver U.S EPA (2008) 473969-27 

870.1300 Acute Inhalation Toxicity – Rat Yes – Data Waiver U.S EPA (2008) 473969-27 

870.2400 Primary Eye Irritation Yes – Data Waiver U.S EPA (2008) 473969-27

870.2500 Primary Dermal Irritation Yes – Data Waiver U.S EPA (2008) 473969-27

870.2600 Dermal Sensitization Yes – Data Waiver U.S EPA (2008) 473969-27 

870.3100 90-Day Oral (one species) Yes – Data Waiver U.S EPA (2008) 473969-27 

870.3250 90-Day Dermal – Rat Yes – Data Waiver U.S EPA (2008) 473969-27 

870.3465 90-Day Inhalation – Rat Yes – Data Waiver U.S EPA (2008) 473969-27 

870.3700 Prenatal Developmental – Rat Preferably Yes – Data Waiver U.S EPA (2008) 473969-27 

870.5100 Bacterial Reverse Mutation Assay Yes – Data Waiver U.S EPA (2008) 473969-27 

870.5300 

870.5375 In vitro Mammalian Cell Assay Yes – Data Waiver U.S EPA (2008) 473969-27 
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iii. Nontarget Organisms and Environment Fate (40 C.F.R. § 158.2060) 

TABLE 5. Summary of Nontarget Organism Data for Sucrose 

Harmonized 

Guideline 

Number 

Data Requirement Has Data Requirement 

Been Addressed? How? Source MRID No. 

850.2100 Avian Acute Oral Toxicity Yes – Data Waiver U.S EPA (2008) 473969-26 

850.2200 Avian Dietary Toxicity Yes – Data Waiver U.S EPA (2008) 473969-26 

850.1075 Fish Acute Toxicity, Freshwater Yes – Data Waiver U.S EPA (2008) 473969-26 

850.1010 Aquatic Invertebrate Acute Toxicity, 

Freshwater Yes – Data Waiver U.S EPA (2008) 473969-26

850.4100 Terrestrial Plant Toxicity, Seedling 

Emergence Yes – Data Waiver U.S EPA (2008) 473969-26 

850.4150 Terrestrial Plant Toxicity, Vegetative 

Vigor Yes – Data Waiver U.S EPA (2008) 473969-26 

880.4350 Nontarget Insect Testing Yes – Data Waiver U.S EPA (2008) 473969-26 

 

E. Risk to Threatened and Endangered Species

Sucrose is a commonly consumed food commodity. Acute and subchronic human health toxicity studies 

have been waived, based upon the long history of safe use of sucrose (U.S. EPA, 2008). Nontarget 

organism studies were waived, based upon the natural occurrence of sucrose (e.g., sugar cane and sugar 

beets), and the packaging of sucrose in a trap for the currently registered product, which is not expected 

to result in exposure to nontarget organisms. Consequently, adverse effects to terrestrial and aquatic 

organisms are expected to be negligible; therefore, the effects determination for endangered/threatened 

species and designated critical habitat is a “No Effect.” EPA anticipates conducting no further analysis of 

potential risks to endangered or threatened species, unless data or information are obtained during the 

Registration Review process that would indicate such an assessment would be needed to inform the 

Agency’s decision. 

F. Endocrine Effects 

As required by the Administrator under the Federal Food, Drug, and Cosmetic Act (FFDCA) section 

408(p), the EPA has developed the Endocrine Disruptor Screening Program (EDSP) and has begun to 

implement the screening program that is to be used to test all pesticides in order to determine whether 

certain substances (including pesticide active and other ingredients) may have an effect in humans or 

wildlife similar to an effect produced by a “naturally occurring estrogen, or other such endocrine effects 

as the Administrator may designate.” 
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FFDCA section 408(p)(4) authorizes the Administrator, by order, to exempt from the requirements of 

the Estrogenic Substances Screening Program a biologic substance or other substance if a determination 

is made that the substance is not anticipated to produce any effect in humans similar to an effect 

produced by a naturally occurring estrogenic substance. 

Between October 2009 and February 2010, the EPA issued test orders/data call-ins for the first group of 

67 chemicals, which contains 58 pesticide active ingredients and 9 inert ingredients. A second list of 

chemicals identified for EDSP screening was published on June 14, 2013,2

 and includes some pesticides 

scheduled for registration review and chemicals found in water. Sucrose is not among the group of 

pesticide active ingredients on the lists to be screened under the EDSP. 

The EPA, as part of this Preliminary Work Plan, believes that sucrose is a substance that would not 

likely produce any effect in humans similar to an effect produced by a naturally occurring estrogenic 

substance. As such, pursuant to Section 408(p)(4), the EPA will determine in the future whether it can 

exempt sucrose from the requirements of the Section 408(p) EDSP. In the event the EPA does determine 

to exempt this substance from the EDSP, an order will be issued. 

For further information on the status of the EDSP, the policies and procedures, the lists of chemicals, 

future lists, the test guidelines and the Tier 1 screening battery, please visit our website at 

http://www.epa.gov/endo/. 

G. Incidents

From January 1, 1991 through November 15, 2013, the Office of Pesticide Programs’ Incident Data 

System (IDS) and Ecological Incident Information System indicates that there have been no reports of 

adverse human, domestic animal, or environmental incidents for the pesticide product containing 

sucrose as its active ingredient. The EPA will consider any incident data or comments submitted in 

response to this Preliminary Work Plan. 

 

2

 See http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPPT-2009-0477-0074 for the second list of chemicals. 
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H. Timeline 

Below is the projected timeline for Registration Review case 5117: Sucrose. 

Activities Estimated Month/Year 

 Opening the Docket 

 Open Docket and 60-Day Public Comment Period for Sucrose December 2013 

 Close Public Comment Period February 2014 

 Case Development 

 Issue Final Work Plan June 2014 

 Issue Data Call-in N/A 

 Data Submission N/A 

 Open 30-Day Public Comment Period for Draft Risk Assessments N/A 

 Close Public Comment Period N/A 

 Registration Review Decision 

 Open 60-Day Public Comment Period for Proposed Registration Review 

 Decision 

November 2014 

 Close Public Comment Period January 2015 

 Final Decision February 2015 

*Estimated Total (years) 1 year and 2 months 

* This schedule is subject to revision should unforeseen issues arise during the registration review process. In the event an 

issue arises, such as the failure to acquire an EDSP exemption, an amended Final Work Plan will be issued at that time. That 

Final Work Plan will identify any newly anticipated data needs and set forth a new timeline. 

I. Guidance for Commenters

 

The public is invited to comment on the EPA’s Preliminary Work Plan and rationale. The areas below 

highlight topics of special interest to the EPA where comments, information and data, or reference to 

sources of additional information could be of particular use. The EPA will consider all comments, as 

well as any additional information or data provided in a timely manner, prior to issuing a Final Work 

Plan for this case. 

i. Environmental Justice 

The EPA seeks to achieve environmental justice, the fair treatment and meaningful involvement of all 

people, regardless of race, color, national origin, or income, in the development, implementation, and 

enforcement of environmental laws, regulations, and policies. To help address potential environmental 

justice issues, the EPA seeks information on any groups or segments of the population who, as a result of 

their location, cultural practices, or other factors, may have unusually high exposure to the pesticidal use 

of sucrose, compared to the general population. Please comment if you are aware of any 

subpopulations that may have atypical, unusually high exposure compared to the general 

population. 
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ii. Water Quality 

 

Sucrose is not identified as a cause of impairment for any water bodies listed as impaired under section 

303(d) of the Clean Water Act.3 In addition, no Total Maximum Daily Loads (TMDLs) have been 

developed for sucrose.4 More information on impaired water bodies and TMDLs can be found at the 

EPA’s website.5 The EPA invites submission of water quality data for this pesticide. To the extent 

possible, data should conform to the quality standards in Appendix A of the Office of Pesticide 

Program’s (OPP) Standard Operating Procedure: Inclusion of Impaired Water Body and Other Water 

Quality Data in OPP’s Registration Review Risk Assessment and Management Process6

 to ensure they 

can be used quantitatively or qualitatively in pesticide risk assessments. 

iii. Trade Irritants 

Through the Registration Review process, the EPA intends to solicit information on trade irritants and, to 

the extent feasible, take steps toward facilitating irritant resolution. The EPA will work to harmonize 

tolerance and international Maximum Residue Limits (MRLs) and, if necessary, may modify tolerance 

levels to do so. Growers and other stakeholders are asked to comment on any trade irritant issues 

resulting from lack of MRLs or disparities between U.S. tolerances and MRLs in key export markets, 

providing as much specificity as possible regarding the nature of the concern. 

Pesticidal food-use of sucrose is covered under an existing exemption from the requirement of a 

tolerance. Moreover, there are no known MRLs for sucrose. Therefore, the EPA does not anticipate that 

current uses of sucrose will pose concerns as trade irritants. 

iv. Additional Information 

 

Stakeholders are also specifically asked to provide information and data that will assist the EPA in 

refining the risk assessments. The EPA is interested in obtaining the following information regarding 

Sucrose: 

 Any data, information, and/or scientific rationale that could be used to fill data gaps 

 Confirmation on the following label information: 

- Sites of application 

- Formulations 

- Application methods and equipment 

- Maximum application rates 

- Frequency of application, application intervals, and maximum number of applications 

- Geographic limitations on use

 Use or potential use distribution (e.g., acreage and geographical distribution of relevant use 

sites) 

 Median and 90th percentile reported use rates (lbs active ingredient/1,000 square feet) from 

usage data – national, state, and county 

 

3

 Based on information provided at http://www.epa.gov/owow/tmdl/. 4

 Based on information provided at http://iaspub.epa.gov/tmdl_waters10/text_search.tmdl_search_form. 5

 See http://www.epa.gov/owow/tmdl/. 6

 This document can be found at http://www.epa.gov/oppsrrd1/registration_review/water_quality_sop.htm. 
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 Application timing (date of first application and application intervals) – national, state, and 

county 

 Usage/use information for nonagricultural uses 

 Typical application interval (days) 

 State or local use restrictions 

 Monitoring data 

 J. Next Steps 

 

After the 60-day comment period closes, the EPA will review and respond to any comments received in 

a timely manner and then issue a Final Work Plan for case 5117: Sucrose. 
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II. BIBLIOGRAPHY 

A. Studies Supporting Registration Review of Sucrose 

MRID 

Number Citation 

Agency 

Receipt 

Date 

45141400 Triangle Laboratories Inc. (2000) Submission of Efficacy Data in Support of the Application for 

Registration of RS21. Transmittal of 1 Study. 

19-Apr2000 

45141401 Roper, C. (2000) Report of the Efficacy of RS21. Unpublished study prepared by Triangle 

Laboratories Inc. 35 p. 

19-Apr2000 

45141500 Triangle Laboratories Inc. (2000) Submission of Product Chemistry Data in Support of the 

Application for Registration of RS21. Transmittal of 1 Study. 

06-Jun2000 

45141501 

Roper, C. (2000) 830 Series Tests of RS21. Unpublished study prepared by Triangle Laboratories 

Inc. 26 p. {OPPTS 830.1600, 830.1620, 830.1650, 830.1700, 830.1750, 830.1800, 830.1900, 

830.6302, 830.6303, 830.6304, 830.6307, 830.6316, 830.6317, 830.6320, 830.7200, 830.7220, 

830.7370, 830.7840, 830.7950} 

06-Jun2000 

47396900 

Bull Run Scientific, VBT. (2008) Submission of Product Chemistry, Toxicity and Efficacy Data 

in Support of the Application for Registration of Bull Run Fly Attractant. Transmittal of 37 

Studies. 

08-Apr2008 

47396903 

Smith, C. (2008) Bull Run Fly Attractant: Field Bioassays to Evaluate Efficacy, Effects on NonTarget Organisms, and Storage Stability. Unpublished study prepared by Bull Run Scientific, 

VBT. 11 p. 

08-Apr2008 

47396906 Smith, C. (2008) Bull Run Fly Attractant: Product Identity, Composition, and Analysis. 

Unpublished study prepared by Bull Run Scientific, VBT. 91 p. 

08-Apr2008 

47396907 Smith, C. (2008) Bull Run Fly Attractant: Physical State, pH and Bulk Density. Unpublished 

study prepared by Bull Run Scientific, VBT. 17 p. 

08-Apr2008 

47396908 Smith, C. (2008) Bull Run Fly Attractant: Corrosion Characteristics. Unpublished study prepared 

by Bull Run Scientific, VBT. 7 p. 

08-Apr2008 

47396909 Smith, C. (2008) Bull Run Attractant: Effects on Non-Target Organisms. Unpublished study 

prepared by Bull Run Scientific, VBT. 7 p. 

08-Apr2008 

47396911 Smith, C. (2008) Bull Run Fly Attractant: Tier I Mammalian Toxicology. Unpublished study 

prepared by Bull Run Scientific, VBT. 8 p. 

08-Apr2008 

47396922 Smith, C. (2008) Sucrose: Product Identity, Composition and Analysis. Unpublished study 

prepared by Bull Run Scientific, VBT. 29 p. 

08-Apr2008 

47396923 Smith, C. (2008) Sucrose: Physical-Chemical Characteristics. Unpublished study prepared by 

Bull Run Scientific, VBT. 20 p. 

08-Apr2008 

47396924 Smith, C. (2008) Sucrose: pH. Unpublished study prepared by Bull Run Scientific, VBT. 13 p. 08-Apr2008 

47396925 Smith, C. (2008) Sucrose: UV/Visible Light Absorption. Unpublished study prepared by Bull 

Run Scientific, VBT. 5 p. 

08-Apr2008 

47396926 Smith, C. (2008) Sucrose: Effects on Non-Target Organisms. Unpublished study prepared by 

Bull Run Scientific, VBT. 7 p. 

08-Apr2008 
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 www.regulations.gov 

 

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47396927 Smith, C. (2008) Sucrose: Tier I Mammalian Toxicology. Unpublished study prepared by Bull 

Run Scientific, VBT. 10 p. 

08-Apr2008 

47406000 Bull Run Scientific, VBT (2008) Submission of Toxicity Data in Support of the Application for 

Registration of Bull Run Fly Attractant. Transmittal of 1 Study. 

18-Apr2008 

47406001 

Noonan, R. (2008) NFTD Disposable Fly Trap Pouch Ingredients: Sample Code: S1-352-A 

(Including Report Supplement). Project Number: X0I198G, 16D/05. Unpublished study prepared 

by Northwest Pacific Laboratories, Inc. 25 p. 

18-Apr2008 

B. U.S. Environmental Protection Agency Risk Assessment Memoranda 

U.S. EPA. 2008. Science Review in Support of the Registration of a new product, Bull Run Fly 

Attractant, containing 3 new active ingredients, sucrose, trimethylamine (99.94% w/w), and 

yeast, and 2 active ingredients in previously registered products from unregistered sources, 

putrescent whole egg solid and indole (99.92% w/w). Memorandum from C. Fuentes to J. 

Fournier, dated September 30, 2008. 

U.S. EPA. 2009. Science Review of registrant response to deficiencies in support of new product 

registration. The proposed new end-use product, Bull Run Fly Attractant, will be inside traps of 

various sizes, and it contains 2 new active ingredients, sucrose, trimethylamine (99.94% w/w), 

and 3 active ingredient in previously registered products from unregistered sources, putrescent 

whole egg solid, yeast and indole (99.92% w/w). Memorandum from C. Fuentes to J. Fournier, 

dated February 26, 2009.