Federal Register / Vol. 63, No. 94 / Friday, May 15, 1998 / Notices 27097

The disclosed thiopeptides can be, but

are not limited to, thiostrepin,

micrococcin P. nosiheptide, siomycin,

sporangiomycin, althiomycin, the

thiocillins and/or thiopeptin, as well as

sulfur-rich peptide antibiotic containing

multiple thiazole rings, produced by

streptomycetes or other peptide

antibiotic-producing organisms.

Image Registration Using Closest

Corresponding Voxels With an Iterative

Registration Process

J Ostuni (LDRR)

Serial No. 08/847,733 filed Apr 28, 1997

(claiming priority date of Apr 29,

1996)

Licensing Contract: John FahnerVihtelic, 301/496-7735 ext. 270

The present invention provides a

novel method of 3D medical image

registration, that is, the alignment of two

or more related 3D images. This method

overcomes problems seen in

conventional registration techniques

arising from mismatching of voxel

intensities. This is of particular

importance when registering images

derived from different techniques, such

as MRI and CT. The invention allows

the registration of images despite the

lack of direct relationship between

intensity levels in the different

techniques, varying patient placement,

and occlusion and noise in the image.

System for Synergistic Combination of

Multiple Automatic Induction Methods

and Automatic Re-Representation of

Data

L Hunter (NLM)

DH Reference No. E–118–96/0; PCT/

US97/08951 filed May 23 1996

Licensing Contact: John Fahner-Vihtelic,

301/496-–7735 ext. 270

The present application describes a

unique prototype of an advanced

framework which relates to the field of

multidimensional data mining, machine

learning, and analysis that has been

named COEV (for COEVolutional).

COEV synergistically combines different

methods of statistical analysis, neural

networks, decision trees and genetic

algorithms for the resolution of data

queries. COEV automatically determines

the optimal methods and data

representations to apply at each step of

inquiry and, as a result, can provide

outcomes that are significantly more

accurate than can be achieved by use of

any one methodology alone. The

invention uses an evolutionary learning

technology to improve predictive

outcomes with continued use. COEV is

designed to advance the accuracy,

flexibility, speed and ease of use of

advanced data analysis technologies.

Characteristics of problems that are

appropriate for the application of the

COEV method are: (1) Appropriate for

machine learning, in that there is a welldefined set of input variables and a clear

prediction target; (2) difficult for

traditional methods, and where a

modest improvement in accuracy over

existing machine learning methods (e.g.,

neural networks) would be significant;

(3) there is a large amount of training

data, ideally thousands of cases.

Possible application areas of interest

include the analysis of high-throughput

screening data for pharmaceutical

discovery, detecting patterns of fraud in

insurance claims, or automating

screening of medical images.

This invention requires further R&D

and testing to make it a practical system

for widespread use.

Dated: May 7, 1998.

Jack Spiegel,

Director, Division of Technology Development

and Transfer, Office of Technology Transfer.

[FR Doc. 98–13011 Filed 5–14–98; 8:45 am]

BILLING CODE 4140–01–M

DEPARTMENT OF HEALTH AND

HUMAN SERVICES

National Institutes of Health

National Institute on Aging; Closed

Meetings

Pursuant to Section 10(d) of the

Federal Advisory Committee Act, as

amended (5 U.S.C. Appendix 2), notice

is hereby given of the following

meetings:

Name of SEP: National Institute on Aging

Special Emphasis Panel Stress, Aging and

Wound Healing.

Date of Meeting: May 27, 1998.

Time of Meeting: 12:00 p.m. to

adjournment.

Place of Meeting: Holiday Inn on the Lane,

Columbus, Ohio.

Purpose/Agenda: To review a program

project application.

Contact Person: Dr. Mary Nekola, Scientific

Review Administrator, Gateway Building,

Room 2C212, National Institutes of Health,

Bethesda, Maryland 20892–9205, (301) 496–

9666.

Name of SEP: National Institute on Aging

Special Emphasis Panel QTL, Analysis of

Age-Related Phenotypes.

Date of Meeting: May 29, 1998.

Time of Meeting: 11:00 a.m. to

adjournment.

Place of Meeting: Chicago O’Hare Marriott,

Chicago, Illinois.

Purpose/Agenda: To review a program

project application.

Contact Person: Dr. James Harwood,

Scientific Review Administrator, Gateway

Building, Room 2C212, National Institutes of

Health, Bethesda, Maryland 20892–9205,

(301) 496–9666.

Name of Committee: National Institute on

Aging, Initial Review Group Biology, Aging

Review Committee.

Dates of Meeting: June 1–2, 1998.

Times of Meeting: June 1–7:30 p.m. to

recess, June 2–8:00 a.m. to adjournment.

Place of Meeting: Chevy Chase Holiday

Inn, 5520 Wisconsin Avenue, Chevy chase,

Maryland 20815.

Purpose/Agenda: To review a program

project application.

Contact Person: Dr. James Harwood,

Scientific Review Administrator, Gateway

Building, Room 2C212, National Institutes of

Health, Bethesda, Maryland 20892–9205,

(301) 496–9666.

Name of Committee: National Institute on

Aging Initial Review Group, Clinical Aging

Review Committee.

Date of Meeting: June 2, 1998.

Time of Meeting: 8:00 a.m. to adjournment.

Place of Meeting: Holiday Inn Bethesda,

8120 Wisconsin Avenue, Bethesda, Maryland

20815.

Purpose/Agenda: to perform the various

grant applications.

Contact Person: Dr. William Kachadorian,

Scientific Review Administrator, Gateway

Building, Room 2C212, National Institutes of

Health Bethesda, Maryland 20892–9205,

(301) 496–9666.

Name of Committee: National Institute on

Aging Initial Review Group, Neurosciences of

Aging Review Committee.

Date of Meeting: June 8–10, 1998.

Times of Meeting: June 8–7:00 p.m. to

recess, June 9–8:00 a.m. to recess, June 10–

8:00 a.m. to adjournment.

Place of Meeting: Chevy Chase Holiday

Inn, 5520 Wisconsin Avenue, Chevy Chase,

Maryland 20815.

Purpose/Agenda: To review grant

applications.

Contact Person: Dr. Louise Hsu, Scientific

Review Administrator, Gateway Building,

Room 2C212, National Institutes of Health,

Bethesda, Maryland 20892–9205, (301) 496–

9666.

Name of SEP: National Institute on Aging

Special Emphasis Panel Alzheimers Disease

Patient Registry.

Date of Meeting: June 10, 1998.

Time of Meeting: 4:00 p.m. to adjournment.

Place of Meeting: Chevy Chase Holiday

Inn, 5520 Wisconsin Avenue, Chevy Chase,

Maryland 20815.

Purpose/Agenda: To review research

project.

Contact Person: Dr. Louise Hsu, Scientific

Review Administrator, Gateway Building,

Room 2C212, National Institutes of Health,

Bethesda, Maryland 20892–9205, (301) 496–

9666.

Name of SEP: National Institute on Aging

Special emphasis Panel Group A.

Date of Meeting: June 10, 1998.

Time of Meeting: 8:00 a.m. to 12:00 noon.

Place of Meeting: Chevy Chase Holiday

Inn, 5520 Wisconsin Avenue, Chevy Chase,

Maryland 20815.

Purpose/Agenda: To pilot study review a

grant application mostly concerning

molecular biology, Alzheimer’s disease,

biochemistry and neurology of aging.

Contact Person: Dr. Arthur Schaerdel,

Scientific Review Administrator, Gateway
27098 Federal Register / Vol. 63, No. 94 / Friday, May 15, 1998 / Notices

Building, Room 2C212, National Institutes of

Health, Bethesda, Maryland 20892–9205,

(301) 496–9666.

Name of SEP: National Institute on Aging

Special Emphasis Panel Group B.

Date of Meeting: June 10, 1998.

Time of Meeting: 8:00 a.m. to 12:00 noon.

Place of Meeting: Chevy Chase Holiday

Inn, 5520 Wisconsin Avenue, Chevy Chase,

Maryland 20815.

Purpose/Agenda: To pilot study review a

grant application mostly concerning

behavior, social activity memory, cognition,

and clinical studies of aging.

Contact Person: Dr. Arthur Schaerdel,

Scientific Review Administrator, Gateway

Building, Room 2C212, National Institutes of

Health, Bethesda, Maryland 20892–9205,

(301) 496–9666.

Name of SEP: National Institute on Aging

Special Emphasis Panel, National Bureau of

Economic Research.

Date of Meeting: June 15, 1998.

Time of Meeting: 8:00 a.m. to 5:00 p.m.

Place of Meeting: Pooks Hill Marriott Hotel,

5151 Pooks Hill Road, Bethesda, Maryland

20814.

Purpose/Agenda: To review grant

applications.

Contact Person: Dr. James Harwood,

Scientific Review Administrator, Gateway

Building, Room 2C212, National Institutes of

Health, Bethesda, Maryland 20892–9205,

(301) 496–9666.

These meetings will be closed in

accordance with the provisions set forth in

secs. 552b(c)(4) and 552b(c)(6), Title 5, U.S.C.

Applications and/or proposals and the

discussions could reveal confidential trade

secrets or commercial property such as

patentable material and personal information

concerning individuals associated with the

applications and/or proposals, the disclosure

of which would constitute a clearly

unwarranted invasion of personal privacy.

(Catalog of Federal Domestic Assistance

Program No. 93.866, Aging Research,

National Institutes of Health)

Dated: May 12, 1998.

LaVerne Y. Stringfield,

Committee Management Officer, NIH.

[FR Doc. 98–13008 Filed 5–14–98; 8:45 am]

BILLING CODE 4140–01–M

DEPARTMENT OF HEALTH AND

HUMAN SERVICES

National Institutes of Health

National Library of Medicine; Meeting

of the Biomedical Library Review

Committee

Pursuant to Pub. L. 92–463, notice is

hereby given of the meeting of the

Biomedical Library Review Committee

on June 17–18, 1998, convening at 9

a.m. in the Board Room of the National

Library of Medicine, Building 38, 8600

Rockville Pike, Bethesda, Maryland.

The meeting on June 17 will be open

to the public from 9 a.m. to

approximately 9:30 a.m., 11:30 a.m. to

noon, and 3:15 p.m. to 3:45 p.m. and on

June 18 from 8:30 a.m. to 8:45 a.m. for

the discussion of administrative reports

and program developments. Attendance

by the public will be limited to space

available. Individuals who plan to

attend and need special assistance, such

as sign language interpretation or other

reasonable accommodations, should

contract Dr. Sharee Pepper at 301–496–

4253 two seeks before the meeting.

In accordance with provisions set

forth in secs. 552b(c)(4) and 552b(c)(6),

Title 5 U.S.C., and sec. 10(d) of Pub. L.

92–463, the meeting on June 17 will be

closed to the public for the review,

discussion, and evaluation of individual

grant applications from 9:30 a.m. to

approximately 11:30 a.m., noon to 3:15

p.m., and 3:45 p.m. to approximately 5

p.m., and on June 18 from 8:45 a.m. to

adjournment. These applications and

the discussion could reveal confidential

trade secrets or commercial property,

such as patentable material, and

personal information concerning

individuals associated with the

applications, disclosure of which would

constitute a clearly unwarranted

invasion of personal privacy.

Dr. Sharee Pepper, Health Scientist

Administrator, Extramural Programs,

national Library of Medicine, 8600

Rockville Pike, Bethesda, Maryland

20894, telephone number: 301–496–

4253, will provide summaries of the

meeting, rosters of the committee

members, and other information

pertaining to the meeting.

(Catalog of Federal domestic Assistance

Program No. 93.879—Medical Library

Assistance, National Institutes of Health)

Dated: May 8, 1998.

LaVerne Y. Stringfield,

Committee Management Officer, NIH.

[FR Doc. 98–13009 Filed 5–14–98; 8:45 am]

BILLING CODE 4140–01–M

DEPARTMENT OF HEALTH AND

HUMAN SERVICES

National Institutes of Health National

Library of Medicine; Meeting of the

Literature Selection Technical Review

Committee

Pursuant to Pub. L. 92–463, notice is

hereby given of a meeting of the

Literature Selection Technical Review

Committee, National Library of

Medicine, on June 11–12, 1998,

convening at 9 a.m. on June 11 and at

8:30 a.m. on June 12 in the Board Room

of the National Library of Medicine,

Building 38, 8600 Rockville Pike,

Bethesda, Maryland.

The meeting on June 11 will be open

to the public from 9 a.m. to

approximately 10:30 a.m. for the

discussion of administrative reports and

program developments. Attendance by

the public will be limited to space

available. Individuals who plan to

attend and need special assistance, such

as sign language interpretation or other

reasonable accommodations, should

contact Mrs. Lois Ann Colaianni at 301–

496–6921 two weeks before the meeting.

In accordance with provisions set

forth in sec. 552b(c)(9)(B), Title 5 U.S.C.,

Pub. L. 92–463, the meeting will be

closed on June 11 from 10:30 a.m. to

approximately 5 p.m. and on June 12

from 8:30 a.m. to adjournment for the

review and discussion of individual

journals as potential titles to be indexed

by the National Library of Medicine.

The presence of individuals associated

with these publications could hinder

fair and open discussion and evaluation

of individual journals by the Committee

members.

Mrs. Lois Ann Colaianni, Scientific

Review Administrator of the Committee,

and Associate Director, Library

Operations, National Library of

Medicine, 8600 Rockville Pike,

Bethesda, Maryland 20894, telephone

number: 301–496–6921, will provide a

summary of the meeting, rosters of the

committee members, and other

information pertaining to the meeting.

Dated: May 8, 1998.

LaVerne Y. Stringfield,

Committee Management Officer, NIH.

[FR Doc. 98–13010 Filed 5–14–98; 8:45 am]

BILLING CODE 4140–01–M

DEPARTMENT OF HEALTH AND

HUMAN SERVICES

Substance Abuse and Mental Health

Services Administration (SAMHSA)

Notice of Meetings

Pursuant to Pub. L. 92–463, notice is

hereby given of the following meetings

of the SAMHSA Special Emphasis Panel

II in May 1998.

A summary of the meetings may be

obtained from: Ms. Dee Herman,

Committee Management Liaison,

SAMHSA, Office of Program Planning

and Coordination (OPPC), Division of

Extramural Activities, Policy, and

Review, 5600 Fishers Lane, Room 17–

89, Rockville, Maryland 20857.

Telephone: (301) 443–7390.

Substantive program information may

be obtained from the individuals named

as Contact for the meetings listed below.

The meetings will include the review,

discussion and evaluation of individual

contract proposals. These discussions

could reveal personal information

concerning individuals associated with

the proposals and confidential and