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SECURITIES AND EXCHANGE
    COMMISSION
 Washington, D.C. 20549
 
 FORM 10-K/A
 
 
 (Amendment
    No. 1)
 
  þ  ANNUAL
    REPORT PURSUANT TO SECTION 13 OR 15(d) OF
 THE SECURITIES EXCHANGE ACT OF
    1934
  For the Fiscal Year ended
    December 31, 2006
  or
  o  TRANSITION
    REPORT PURSUANT TO SECTION 13 OR 15(d) OF
 THE SECURITIES EXCHANGE ACT OF
    1934
  For the transition period from
    
    to
  Commission File
    No. 0-29100
  eResearchTechnology,
    Inc.
    Delaware

22-3264604(State of Incorporation)

(I.R.S. Employer Identification No.)30 South 17th Street
    Philadelphia, PA

19103(Address of Principal Executive
    Offices)

(Zip Code)   (215) 972-0420
   Securities registered pursuant to Section 12(b) of the
    Act:
  Title of Class

Name of Each Exchange on Which
    RegisteredCommon Stock, $.01 par value

The Nasdaq Stock Market LLC   Securities registered pursuant to Section 12(g) of the
    Act: None
  o þ
  o þ
  þ o
  Regulation S-K Form 10-K Form 10-K. þ
  Rule 12b-2
  Large
    accelerated filer o
    Accelerated
    filer þ
    Non-accelerated
    filer o  Rule 12b-2 o þ
      
 Class

Outstanding at February 27,
    2007Common Stock, $.01 par value
    per share

50,229,832 shares  
  DOCUMENTS
    INCORPORATED BY REFERENCE




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Explanatory
    Note
 
 
  Form 10-K
 
  ITEM 15.
    EXHIBITS AND
    FINANCIAL STATEMENT SCHEDULES  Form 10-K:
  1.
    The consolidated financial statements of eResearchTechnology,
    Inc. (the Company) filed as a part of this
    Form 10-K
    are listed on the attached Index to Consolidated Financial
    Statements and Financial Statement Schedule at F-1.2.
    The financial statement schedule of the Company filed as a part
    of this
    Form 10-K
    is listed in the attached Index to Consolidated Financial
    Statements and Financial Statement Schedule at F-1.3.
    Exhibits.  3
.1

Restated Certificate of
    Incorporation, as amended.(9)3
.2

Bylaws.(1)3
.3

Amendment to Bylaws.(2)3
.4

Certificate of Merger between the
    Company and eRT Operating Company.(6)4
.1

Form of Stock Certificate.(6)10
.1

Registration Rights Agreement
    dated August 27, 1999.(3)10
.3

2003 Stock Option Plan, as
    amended.(13)*10
.7

1996 Stock Option Plan, as
    amended.(6)*10
.9

2005 Bonus Plan.(10)*10
.10

2005 Amended Bonus Plan.(11)*10
.11

2006 Bonus Plan.(12)*10
.23

Sublease Agreement between the
    Company and Raytheon Engineers & Constructors, Inc.(2)10
.25

Amendment to the Sublease
    Agreement between the Company and 17th Ludlow Property,
    L.L.C.(7)10
.26

Amendment to the Sublease
    Agreement between the Company and 17th Ludlow Property,
    L.L.C.(8)10
.30

Promissory Note to Wachovia Bank,
    National Association.(14)10
.31

Loan Agreement with Wachovia Bank,
    National Association.(14)10
.40

Management Employment Agreement
    effective February 7, 2006 between Joseph Esposito and the
    Company.(12)* 37




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10
.41

Amendment to Management Employment
    Agreement effective August 16, 2004 between Dr. Joel
    Morganroth and the Company.(9)*10
.42

Amendment to Management Consulting
    Agreement effective January 1, 2005 between Dr. Joel
    Morganroth and the Company.(10)*10
.44

Management Employment Agreement
    effective August 20, 2004 between Dr. Jeffrey Litwin
    and the Company.(9)*10
.45

Management Employment Agreement
    effective August 20, 2004 between Vincent Renz and the
    Company.(9)*10
.46

Management Employment Agreement
    effective August 20, 2004 between Scott Grisanti and the
    Company.(9)*10
.47

Amendment to Management Consulting
    Agreement effective January 1, 2006 between Dr. Joel
    Morganroth and the Company.(12)*10
.48

Management Employment Agreement
    effective June 23, 2006 between Michael J. McKelvey and the
    Company.(13)*10
.49

Management Employment Agreement
    effective May 17, 2006 between Richard A. Baron and the
    Company.(13)*10
.50

Amendment to Management Employment
    Agreement effective June 12, 2006 between Richard A. Baron
    and the Company.(13)*10
.52

Lease Agreement dated
    August 18, 2000 between Advance/GLD 2 L.L.C. and the
    Company.(4)10
.54

Lease Agreement dated
    September 28, 2004 between Royal and Sun Alliance Insurance
    PLC and the Companys subsidiary, eResearchTechnology
    Limited.(10)10
.56

Management Employment Agreement
    effective May 21, 2001 between Dr. Joel Morganroth and
    the Company.(5)*10
.57

Management Consulting Agreement
    effective May 21, 2001 between Dr. Joel Morganroth and
    the Company.(5)*10
.59

Attornment Agreement between
    17th Ludlow Property, L.L.C. and the Company.(6)21
.1

Subsidiaries of the Registrant.(15)23
.1

Consent of KPMG LLP.(15)31
.1

Certification of Chief Executive
    Officer.(15)31
.2

Certification of Chief Financial
    Officer.(15)31
.3

Certification of Chief Executive
    Officer.31
.4

Certification of Chief Financial
    Officer.32
.1

Statement of Chief Executive
    Officer Pursuant to Section 1350 of Title 18 of the
    United States Code.32
.2

Statement of Chief Financial
    Officer Pursuant to Section 1350 of Title 18 of the
    United States Code.  
 38




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*
    
    Management contract or compensatory plan or arrangement.(1)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys Registration
    Statement on
    Form S-1,
    File
    No. 333-17001,
    declared effective by the Securities and Exchange Commission on
    February 3, 1997.(2)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys
    Form 10-K
    on March 31, 1999.(3)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys
    Form 8-K
    on September 9, 1999.(4)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys
    Form 10-Q
    on November 13, 2000.(5)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys
    Form 10-Q
    on August 10, 2001.(6)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys
    Form 10-K
    on March 12, 2002.(7)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys
    Form 10-Q
    on November 7, 2003.(8)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys
    Form 10-Q
    on May 3, 2004.(9)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys
    Form 10-Q
    on November 4, 2004.(10)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys
    Form 10-K
    on March 11, 2005.(11)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys
    Form 10-Q
    on November 3, 2005.(12)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys
    Form 10-K
    on March 10, 2006.(13)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys
    Form 10-Q
    on August 4, 2006.(14)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys
    Form 10-Q
    on November 9, 2006. 
  (15)
    
    Incorporated by reference to the exhibit with the same number,
    filed in connection with the Companys Form 10-K on
    March 9, 2007. 
 39




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SIGNATURES
 
 
   
 
  eResearchTechnology, Inc.
 
 
   
 
 By:
    Michael J.
    McKelvey 
 
 
  
 
  
 41