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Exhibit 10.36
 Manufacturing and Supply Agreement
 Manufacturing and Supply Agreement Agreement Effective Date Alexza Pharmaceuticals, Inc. Alexza Autoliv ASP, Inc. Autoliv
 Recitals
 A. Development Agreement
 B.
 In consideration
 ARTICLE 1  Definitions
  1.1 Affiliate
 1.2 Alexza Field
 1.3 Alexza Indemnitees
 1.4 Alexza IP
 1.5 Annual Purchase Order
 1.6 Autoliv Field
 1.7 Autoliv Indemnitees
 1.8 Autoliv IP
 
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1.9 Autoliv Patents Exhibit F
 1.10 Background Technology
 1.11 Build Forecast
 1.12 Chemical Heat Package Exhibit A
 1.13 Confidential Information
 1.14 Consultant Services Agreement
 1.15 Development Agreement
 1.16 Disclosing Party
 1.17 ECR
 1.18 Finished Product
 1.19 Foreign Counterparts
 1.20 Healthcare Field
 1.21 Healthcare Product
 1.22 Initial Term
 
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1.23 Intellectual Property Rights
 1.24 Joint IP
 1.25 Key Personnel
 1.26 Mandatory Engineering Change
 1.27 Mutual CDA
 1.28 New Discoveries
 1.29 Operations Representative
 1.30 Optional Engineering Change
 1.31 Pilot Production Line
 1.32 Purchase Date
 1.33 Quality Terms
 1.34 Receiving Party
 1.35 Release or Actual Order
 1.36 Second Generation Agreement
 
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1.37 Second Generation Package Exhibit A
 1.38 Specifications Exhibit B
 1.39 Strategic Forecast
 1.40 Third Party
 ARTICLE 2  Manufacturing
 2.1 Manufacture
 2.2 Non-delegable Responsibility
 2.3 Autoliv Personnel
 (a) Key Personnel Exhibit D Key Personnel
 (b) Operations Representative Exhibit D Operations Representative
 
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2.4 Meetings
 2.5 Exclusivity
 (a) Development IP
 (b) Healthcare Product
 2.6 Right of Negotiation Second
Generation Agreement
 
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been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule
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ARTICLE 3  Chemical Heat Package Forecasting and Ordering
 3.1 Purchase Right.
 3.2 Strategic Forecast Strategic Forecast
 3.3 Annual Purchase Order Annual Purchase Order Exhibit C
 3.4 Build Forecast Build Forecast
 
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3.5 Releases.
 ARTICLE 4  Delivery
 4.1 Delivery Schedule
 4.2 Packaging Requirements.
 
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ARTICLE 5  Purchase Prices; Royalties; Payment
 5.1 Purchase Prices.
 (a) Purchase Prices During the Initial Term Exhibit C.
 (b) Purchase Prices After the Initial Term Exhibit C
 5.2 Purchase of Pilot Production Line
 5.3 Purchase Price Payments.
 
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5.4 Expense Reimbursement
 5.5 Taxes.
 5.6 Royalty Payments and Reports.
 (a)
 (b)
 
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5.7 Currency. dollars $
 5.8 Audits
 (a)
 (b)
 (c)
 (d)
 
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ARTICLE 6  Change Orders
 6.1 Optional Chemical Heat Package Changes. ECR
 6.2 Mandatory Engineering Change.
 ARTICLE 7  Quality Terms; Improvements; Failure Analysis; Disaster Recovery
 7.1 Quality Terms. Exhibit E Quality
Terms
 7.2 Failure Analysis.
 7.3 Disaster Recovery Plans.
 
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ARTICLE 8  Representations and Warranties
 8.1 Mutual Representations and Warranties.
 (a) Corporate Power.
 (b) Due Authorization.
 (c) Binding Agreement.
 8.2 Representations and Warranties Concerning Chemical Heat Packages
 8.3 Representations and Warranties Concerning Intellectual Property Rights
 (a)
 (b) Exhibit F
 
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8.4 Disclaimer
 ARTICLE 9  Intellectual Property
 9.1 Background Technology. Background
Technology
 9.2 Inventorship.
 9.3 Autoliv Inventions. Autoliv IP
 9.4 Alexza Inventions. Alexza IP
 9.5 Joint Inventions Joint IP
 
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9.6 Patent Applications.
 9.7 Licenses to Autoliv.
 9.8 Licenses to Alexza.
 
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ARTICLE 10  Term; Termination
 10.1 Term
 10.2 Termination for Convenience
 10.3 Termination For Failure to Agree Upon Price
 10.4 Termination for Cause
 (a)
 (b)
 (c)
 10.5 Consequences of Termination.
 (a)
 
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(b)
 (c)
 (d)
 (e)
 (f)
 
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ARTICLE 11  Indemnification; Insurance Coverage
 11.1 Indemnification by Alexza. Autoliv Indemnitees
 11.2 Indemnification by Autoliv. Alexza
Indemnitees
 11.3 Procedure.
 11.4 Insurance Coverage.
 
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ARTICLE 12  Confidentiality
 12.1 Nondisclosure of Confidential Information
 12.2 Exceptions Disclosing Party Receiving Party
 (a)
 (b)
 (c)
 (d)
 (e)
 12.3 Authorized Disclosure
 (a)
 
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(b)
 12.4 Terms of Agreement.
 12.5 Termination of Prior Agreements
 ARTICLE 13  Miscellaneous
 13.1 Assignment. provided, however
 13.2 Agency.
 
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13.3 Employees.
 13.4 Amendment.
 13.5 Notices.
  
  
  13.6 Force Majeure.
 
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13.7 Export Control
 13.8 Severability.
 13.9 Governing Law and Venue
 13.10 Construction
 13.11 Cumulative Rights.
 13.12 Waiver.
 13.13 Entire Agreement.
 
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13.14 Counterparts
 13.15 Further Assurances
  Alexza Pharmaceuticals, Inc.
    
    Autoliv ASP, Inc./s/ Thomas B. King

Signature
    
    /s/ Michael J. Ward

SignatureThomas B. King

Name
    
    Michael J. Ward

NamePresident & CEO

Title
    
    President, Autoliv ASP

TitleNovember
2, 2007

Date
    
    November 2, 2007

Date
 List of Exhibits
 A.
    
    Chemical Heat Package Drawing No. PNR002119, Chemical Heat PackageB.
    
    Technical Requirements for Chemical Heat Packages, SPS 002002C.
    
    Purchase PriceD.
    
    Key Personnel; Operations RepresentativeE.
    
    Quality TermsF.
    
    Autoliv Patents and Patent Applications
 +++++++++++++++++++++++++++++++++++
 
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Exhibit A  Chemical Heat Package Description  [ * ]
 
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been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule
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Exhibit B
 Technical requirements for Chemical Heat Packages, SPS 002002
 (ALEXZA PHARMACEUTICALS LOGO)
    
    Released For:
    
    101168 Rev. 01MASTER FILETechnical Requirements for Chemical Heat Package
 1.0
    
    PURPOSE This document lists requirements that the chemical heat package (PNR002119, Heat
Package, Seam Weld, Binder Free) needs to meet when supplied to Alexza Pharmaceuticals.2.0
    
    SCOPE This document defines requirements which apply to the CPD chemical heat package. It
is controlled and maintained within Alexza Pharmaceuticals document control system. All
changes will be made under the Alexza Change Control System.3.0
    
    RESPONSIBILITIES It is the responsibility of those organizations noted below to read and understand
this document. It is the responsibility of the Project Leader to generate and maintain this
document.
 Product Research and Development
    
    Review and approve the 101168Manufacturing
    
    Review and approve the 101168Quality Assurance
    
    Review and approve the 101168Supply Chain Management
    
    Review and approve the 101168
 4.0
    
    REFERENCES ISTA procedure 3A, Packaged-Products for Parcel Delivery System Shipment 70kg (150
lb) or Less.IEC/EN 60068-2-27, Basic environmental testing procedures  Part 2: Tests; test Ea and
guidance: ShockIEC/EN 60068-2-64, Environmental testing  Part 2: Test methods  Test Fh: Vibration,
broad-band random (digital control) and guidance
 
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IEC/EN 60068-2-6, Environmental testing  Part 2: Tests; test Fc: Vibration (sinusoidal)
 
    
    ALXSPSD-0010, Thermal Testing of Heat Packages
    
    ALXSPSD-0023, Leak Check and Electrical Check
 5.0
    
    DEFINITIONS AND ACRONYMS
 Cpk
    
    Type of process capability index. Normally expressed
as the minimum of [(upper specifications limit 
mean)/3s , (mean  lower specification
limit)/3s]Header
    
    Component of heat package.Heat shield
    
    Component of heat package.HP
    
    Heat PackageIEC
    
    International Electrochemical CommissionISO
    
    International Organization for StandardizationISTA
    
    International Safe Transit AssociationLid
    
    Component of heat packageμ
    
    Micronμm
    
    Micrometerms
    
    MillisecondsMultiple initiations
    
    The reaction of reactant coated on the inside of the
heat package starts at multiple locations.NMT
    
    Not more thanNormal heat package
    
    Heat package meets all the performance requirements
as specified in section 7.0 of this document.Propagation time
    
    Time from actuation (reactant on surface is actuated)
until the heating reaction is complete (all reactant
has reacted).RSD
    
    Relative Standard Deviations
    
    Standard deviationT250
    
    Average surface temperature measured 250 ms after
actuation.TBD
    
    To be determinedTray
    
    Component of heat package
 
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6.0
    
    OVERALL DESCRIPTION
 6.1
    
    The Chemical Heat Package (PNR002119) The heat package assembly consists of a lid and tray coated on one side with
reactant, a header with a welded bridge wire and starter material, and a heat
shield. The heat package is seam welded along the edges of the lid and tray flanges
and the header is sealed with UV curable adhesive.
 Figure 1  Exploded View of a Heat Package
 
 7.0
    
    PERFORMANCE REQUIREMENTSDuring lot acceptance testing, heat packages should be verified to meet requirements 1, 2,
3, 4, 6, 7 and 12. Requirements 1, 2, 3, 4 and 6 are destructive tests and should therefore
be verified for a representative sample of heat packages from a particular lot.
 TestingAttribute
    
    Method
    
    Requirement1. Temperature
    
    ALXSPSD-0010
    
    [ * ]2. Temperature uniformity
    
    ALXSPSD-0010
    
    [ * ]3. Multiple initiations
    
    ALXSPSD-0010
    
    [ * ]4. Propagation time
    
    ALXSPSD-0010
    
    [ * ]5. Pressure inside HP
    
    ALXSPSD-0010
    
    [ * ]6. Heat package weld and metal integrity
    
    ALXSPSD-0011
    
    [ * ]
 
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TestingAttribute
    
    Method
    
    Requirement7. He leak rate before actuation
    
    ALXSPSD-0023
    
    [ * ]8. He leak rate after actuation  use
environment, temperature
    
    ALXSPSD-0023
    
    [ * ]9.He leak rate after actuation,
 use environment, altitude
    
    ALXSPSD-0023
    
    [ * ]10. Actuation reliability,  use
environment temperature
    
    ALXSPSD-0010
    
    [ * ]11. Actuation reliability,  use
environment altitude
    
    ALXSPSD-0010
    
    [ * ]12. Header resistance before actuation
    
    ALXSPSD-0023
    
    [ * ]13. Header resistance after actuation
    
    ALXSPSD-0023
    
    [ * ]14. Shelf life
    
    N/A
    
    [ * ]15. Shelf life
    
    N/A
    
    [ * ]16. Shipping requirement
    
    N/A
    
    [ * ]17. Mechanical Shock
    
    N/A
    
    [ * ]18. Sinusoidal Vibration
    
    N/A
    
    [ * ]19. Random Vibration (broad band)
    
    N/A
    
    [ * ]20. Orientation
    
    TBD
    
    [ * ]
 +++++++++++++++++++++++++++++++
 
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been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule
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Exhibit C
 Purchase Price
  Annual Quantity
    
    Purchase Price(in units)
    
    (in USD)[ * ]
    
    [ * ][ * ]
    
    [ * ][ * ]
    
    [ * ][ * ]
    
    [ * ][ * ]
    
    [ * ][ * ]
    
    [ * ][ * ]
    
    [ * ]
 ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
 
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been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule
24b-2 of the Securities Exchange Act of 1934, as amended.




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Exhibit D
 Key Personnel; Operations Representative
 A.
    
    Key Personnel:
 Name
    
    Position
    
    Role[ * ]
    
    [ * ]
    
    [ * ][ * ]
    
    [ * ]
    
    [ * ][ * ]
    
    [ * ]
    
    [ * ][ * ]
    
    [ * ]
    
    [ * ][ * ]
    
    [ * ]
    
    [ * ]
 B.
    
    Operations Representative:[ * ]
 +++++++++++++++++++++++++++++++++++++++++
 
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been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule
24b-2 of the Securities Exchange Act of 1934, as amended.




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Exhibit E
 Quality Terms
 1.
    
    PURPOSEThis exhibit defines the quality responsibilities between Alexza and Autoliv with
respect to the quality assurance of the CPD Heat Packages manufactured by Autoliv for
Alexza2.
    
    SCOPEThis exhibit is applicable to the CPD Heat Packages manufactured by Autoliv.3.
    
    QUALITY SYSTEMAutoliv shall establish, document and maintain a quality system in accordance with
ISO/TS 16949 Quality Management System Standard. Autoliv shall notify Alexza in advance
in the event that Autoliv is required to change their Quality Management Standard
(ISO/TS 16949).The Autoliv quality system shall consist of written procedures for the control of
planned and unplanned changes to materials, packaging components, suppliers, equipment,
processing steps, device component requirements, sampling test methods and releasing
requirements.4.
    
    QUALITY AND BUSINESS REVIEWAlexza and Autoliv shall conduct Quality and Business Reviews according to the
manufacturing and supply agreement. The appropriate Alexza & Autoliv Quality Engineer
and/or Supply Team Lead or other appropriate personnel shall lead such event(s).5.
    
    COMPLIANCEAutoliv shall manufacture Alexza products in compliance with Autolivs established
quality system procedures, ISO/TS 16949 standard and applicable regulations. Autoliv
shall be responsible for maintaining certification to the current ISO/TS 16949 standard.6.
    
    AUDITSAlexza shall have the right, upon reasonable notice to Autoliv and during regular
business hours to audit, observe (person in plant), or inspect the facilities being used
by Autoliv for production and storage of the CPD Heat Package. Alexza shall audit for
compliance to the approved Autoliv procedures relating to manufacturing of CPD Heat
Packages and to the ISO/TS 16949 standard. Autoliv shall within thirty (30) calendar
days of receipt of the written audit letter, remedy or cause the remedy of any
deficiencies
 
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which may be noted. If deficiencies cannot reasonably be remedied within such thirty
(30) business-day period, a written plan to remedy such deficiencies will be presented
to Alexza.7.
    
    REGULATORY INSPECTIONSAutoliv shall notify Alexza within twenty four (24) hours of any inspection notification
from any regulatory agency specifically related to the manufacture and storage of CPD
Heat Packages. Autoliv shall provide Alexza copies of any inspection reports that it
receives from any regulatory agency or any notice of any claim or action by any agency
relating to non-compliance with any applicable laws, rules or regulations. Autoliv shall
contact Alexza for instructions with regards to validity of a request about Alexza
products by a regulatory agency. Except to the extent as may be required by law, Autoliv
shall not communicate directly with any regulatory agency (such as FDA or sanctioning
authority) regarding the CPD Heat Package except through or with the explicit review and
approval of Alexza.8.
    
    DESIGN SPECIFICATIONSSpecifications and drawings for CPD Heat Package components, packaging components, and
the completed CPD Heat Package will be created and approved by Alexza according to
Alexzas change control process. Approved specifications and drawings will be
transferred to Autoliv by Alexza.9.
    
    MANUFACTURING INSTRUCTIONSAlexza and Autoliv are jointly responsible for ensuring the appropriate process controls
are implemented. Autoliv is responsible for creation and approval of the manufacturing
control plan(s) according to Autolivs change control process. Alexza will approve the
Autoliv manufacturing control plan(s) as well as references within the CPD Heat Package
control plan(s)10.
    
    CHANGE CONTROLAutoliv shall not make changes to the design, materials, packaging components,
requirements or process changes affecting safety, specifications, or stability
requirements of the Alexza CPD Heat Package without prior written approval from Alexza.
Autoliv is responsible for notifying and obtaining Alexzas approval for any changes to
the manufacturing control plan(s) prior to implementation and for providing Alexza with
a copy of the most current approved control plan(s).11.
    
    IDENTIFICATION & TRACEABILITYAutoliv shall maintain a system to assure proper identification and acceptance status of
materials, components and products throughout the manufacturing cycle. The
manufacturing records shall allow for traceability to process, equipment, personnel, and
 
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materials and components used in the manufacturer of each lot or batch of CPD Heat
Packages. The extent of traceability to the materials and components shall be defined
in the manufacturing control plan(s).12.
    
    NON-CONFORMANCESAutoliv will notify Alexza of all non-conformances, as determined by the control plan,
associated with manufacturing or testing CPD Heat Packages that are being reviewed for
shipment of the lot to Alexza or that affect product that has already been shipped to
Alexza.13.
    
    LOT RELEASE AND CERTIFICATE OF ANALYSISAutoliv is responsible for reviewing completed manufacturing and testing records to
ensure each lot of CPD Heat Packages has been manufactured and tested in accordance to
the approved manufacturing instructions and that any deviations to the process have been
thoroughly investigated. Autoliv is responsible for disposition of each lot of CPD Heat
Packages prior to shipment to Alexza. Autoliv will generate a Certificate of
Conformance (C of C) for each lot and the C of C will be provided to Alexza. The C of C
will contain traceability to the lot and a compliance statement indicating the lot has
been manufactured and tested according to the approved control plan(s) and meets all
requirements of the product specification. Upon request, Alexza may request copies of
the completed manufacturing records, test data, or other related records associated with
the lot.14.
    
    ACCEPTANCEAlexza reserves the right to reject any product that is found not to be in conformance
with the approved product specifications or found not to have been manufactured
according to the approved control plan(s).15.
    
    RECORDS RETENTIONAll documentation (manufacturing records, packaging records, inspection records, batch
tickets/card/records, and quality records, such as calibration logs, training records)
generated during the manufacturing process will be maintained by Autoliv for a minimum
of seven (7) years. Autoliv shall notify Alexza prior to destruction of any records
related to the manufacture of device component and relevant quality system records and
transfer such records to Alexza upon request.16.
    
    FAILURE ANALYSISWhen requested by Alexza, Autoliv will perform a complete investigation on returned heat
package(s) in a timely manner sufficient to determine the root cause of the abnormal
condition. An investigation report will be written and submitted to Alexza for review
and approval as soon as reasonably possible.
 
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been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule
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+++++++++++++++++++++++++++++++++++++++++
 
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been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule
24b-2 of the Securities Exchange Act of 1934, as amended.




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Exhibit F
 AUTOLIV PATENTS AND PATENT APPLICATIONS
 Patent Description:
    
    Patent Number:
    
    Also Published as:[ * ]
    
    [ * ]
    
    [ * ][ * ]
    
    [ * ]Pending Autoliv Review:
    
    Internal File Number:[ * ]
    
    [ * ]Autoliv Trade Secret:
    
    File Number:[ * ]
    
    [ * ]
 
 [ * ] =
    
    Certain confidential information contained in this document, marked by brackets, has
been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule
24b-2 of the Securities Exchange Act of 1934, as amended.