**Exhibit 31.1**

**CERTIFICATION PURSUANT TO**

**SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002**

I,            Peter Hughes, certify that:
| 1. | I have reviewed this annual report on Form 10-KSB of Arthro                        Pharmaceuticals Inc.; |
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| 2. | Based on my knowledge, this report does not contain any                        untrue statement of a material fact or omit to state a material fact                        necessary to make the statements made, in light of the circumstances under                        which such statements were made, not misleading with respect to the period                        covered by this report; |
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| 3. | Based on my knowledge, the financial statements, and other                        financial information included in this report, fairly present in all                        material respects the financial condition, results of operations and cash                        flows of the small business issuer as of, and for, the periods presented in                        this report; |
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| 4. | The small business issuer's other certifying officer(s) and                        I are responsible for establishing and maintaining disclosure controls and                        procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) for                        the small business issuer and have: |
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|   | (a) | Designed such disclosure controls and procedures, or caused                        such disclosure controls and procedures to be designed under our                        supervision, to ensure that material information relating to the small                        business issuer, including its consolidated subsidiaries, is made known to                        us by others within those entities, particularly during the period in which                        this report is being prepared; |
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|   | (b) | Evaluated the effectiveness of the small business issuer's                        disclosure controls and procedures and presented in this report our                        conclusions about the effectiveness of the disclosure controls and                        procedures, as of the end of the period covered by this report based on                        such evaluation; and |
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|   | (c) | Disclosed in this report any change in the small business                        issuer's internal control over financial reporting that occurred during the                        small business issuer's most recent fiscal quarter (the small business                        issuer's fourth fiscal quarter in the case of an annual report) that has                        materially affected, or is reasonably likely to materially affect, the                        small business issuer's internal control over financial reporting;                        and |
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| 5. | The small business issuer's other certifying officer(s) and                        I have disclosed, based on our most recent evaluation of internal control                        over financial reporting, to the small business issuer's auditors and the                        audit committee of the small business issuer's board of directors (or                        persons performing the equivalent functions): |
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|   | (a) | All significant deficiencies and material weaknesses in the                        design or operation of internal control over financial reporting which are                        reasonably likely to adversely affect the small business issuer's ability                        to record, process, summarize and report financial information;                        and |
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|   | (b) | Any fraud, whether or not material, that involves management                        or other employees who have a significant role in the small business                        issuer's internal control over financial reporting. |
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Date:            August 29, 2007

/s/            Peter Hughes

Peter            Hughes, President and Chief Executive Officer

(Principal Executive Officer and Principal Financial Officer)

 

CW1376479.1