SAT Report

PMN Number: P-14-0234

SAT Date: 1/14/2014

Print Date: 1/31/2014

Related cases:

Health related cases: )

Ecotox related ca

Concern levels:

Type of Concern: Health Eco Comments

Level of Concern: 1-2 2

 Persistence Bioaccum Toxicity Comments

2 11

Exposure Based Review:

Health: No

Ecotox: No

Routes of exposure: Health: Drinking Water Inhalation 

Ecotox: All releases to water

Fate: ;

Keywords:

 Keywords: LUNG; IRR-E,L,MM; AQUATOX-A,C

Summary of Assessment:

 Fate:

Fate Summary: P-14-0234

FATE: MW = 

Liquid with MP = 11 C (M)

S = Disp. / 10 g/L at 25 °C (ICB / M)

VP < 1.0E-6 torr at 25 C (E)

BP > 400 C (E)

H < 1.00E-8 (E)

POTW removal (%) = 90 via sorption and biodeg

Time for complete ultimate aerobic biodeg = mo

Sorption to soils/sediments = moderate

EPA SANITIZED Page 1 of 4
PBT Potential: P2B1

*CEB FATE: Migration to ground water = slow - moderate

 Health:

 Health Summary: Absorption is poor all routes based on physical/chemical 

properties. The PMN substance is a , with activity increasing with 

increasing number of . There are concerns for lung effects and irritation to the eye, lung, 

and mucous membranes, based on t activity. There is particular concern for eye 

irritation from because they can anesthetize the eye and allow significant 

damage to occur before adverse effects are realized.

 Test Data: slightly irritating to 

 not irritating to 

 Ecotox:

Test Organism Test 

Type

Test End 

Point

Predicted Measured Comments

96-h LC50 1.2 1.2

daphnid 48-h LC50 1.2

green algal 96-h EC50 1.2

_ chronic value 0.24

daphnid _ chronic 

value

0.24

algal _ chronic 

value

0.30

Sewage Sludge 3-h EC50 _

Sewage Sludge _ Chronic 

Value

_

Ecotox Values Comments: Predictions are based on SARs for 

; SAR chemical class = 

; 

effective concentrations based on 100% active ingredients and mean measured concentrations; 

hardness <180.0 mg/L as CaCO3; and TOC <2.0 mg/L;

Initial Submission Review of for P-14-0234

PMN Chemical Name:

An acute fish toxicity test was conducted in 2002 with P-14-0234 by 

 for ). The PMN substance is a pigment

dispersant used in colorant manufacturing used for textile printing, imported as a 2% dispersion 

EPA SANITIZED Page 2 of 4
in water EPA determined that P-14-0234 is in the SAR chemical class 

. The PMN is a liquid with a viscosity of 500 

mPa*s at 30oC, melting point of 11°C, an estimated boiling point > 400°C, an estimated vapor 

pressure < 1 x 10-6 Torr and a water solubility of 10 g/L. The acute fish test complied with 

) for: 1) temperature and water hardness values and, 2) species and 

number of organisms per replicate.

:

In a 96-hour toxicity test, ) were exposed to a dispersion 

product of P-14-0234 (purity not provided) under semi-static conditions with daily renewal. The 

test substance was reported to be a light brown, slightly turbid, viscous liquid. This study was 

reported to follow ) ”. Following a 

range-finding test, single replicates of seven were exposed to a dilution water control 

(dechlorinated tap water) or the test substance at nominal concentrations of 18, 32, 56, 100 or 

180 mg/L. The test solutions were prepared through direct addition of test substance to water. 

Amounts of test material were each separately dissolved into a final volume of 200 mL of 

dechlorinated tap water, with the aid of ultrasonication for approximately 5 minutes. The test 

substance was then dispersed into a final volume of 20 liters of dechlorinated tap water, to give 

the desired nominal concentrations. The test material preparations were observed to be clear, 

colorless solutions throughout the duration of the test. During the test, the water temperature was 

reported to be 14oC and dilution water hardness was 100 mg CaCO3 /L. A loading of 0.23 g 

 These responses were increased pigmentation, loss of equilibrium, increased pigmentation 

with loss of equilibrium, loss of equilibrium with swollen abdomens and the presence of 

. The % mortality at 0 (control), 18, 32, 56, 100 and 180 mg/L was 0, 0, 0, 43, 100 

and 100%, respectively. Based on nominal concentrations, the 96-hour LC50 of the dispersion 

product is 59 mg/L. substance so that the revised LC50 is 1.2 

mg/L. This .

96-hour LC50 = 1.2 mg/L 

Conclusions: 

The is valid. Details recommended under such as test substance 

purity, analysis of test substance concentration and duration of to light/dark cycles 

and O2 concentration were not reported. However, the results concur with and 

support the SAR predictions for the . Therefore, the chronic and 

concentrations of concern (CoCs) for P-14-0234, based on SAR predictions for 

, remain 24 ppb and 240 ppb, respectively.

Ecotox Study Reviewer: Tracy Wright January 28, 2014

Factors Values Comments

Assessment Factor 10

Concentration of Concern 24

EPA SANITIZED Page 3 of 4
(ppb)

SARs

SAR Class

Ecotox Category 

Ecotox Factors Comments: 

 SAT Chair: Doritza Pagan-Rodriguez

EPA SANITIZED Page 4 of 4