EXHIBIT 10.99**AGREEMENT**     THIS AGREEMENT (hereinafter “Agreement”) is made and entered into by and between Larry T.Mimms, Ph.D. (hereinafter “DR. MIMMS”), on the one hand, and Gen-Probe Incorporated, its parents,subsidiaries, related entities, predecessors, successors, officers, directors, agents, employeesand assigns (hereinafter collectively “GEN-PROBE”), on the other hand.     1. **Resignation of Employment****.**DR. MIMMS hereby resigns from all positions ofemployment with GEN-PROBE and its affiliates, including but not limited to his position asExecutive Vice President, Research & Development, as of April 16, 2007 (the “Resignation Date”).DR. MIMMS’ employment with GEN-PROBE shall terminate, for all purposes, as of the Resignation Date.     2. **Consideration to Dr. Mimms and Tax Liability.**          a. **Compensation****.**GEN-PROBE agrees to pay DR. MIMMS severance benefits at a rate equalto his current Base Salary (less applicable withholding taxes) for the period commencing on theResignation Date and continuing through July 16, 2008. These severance payments shall be paid onGEN-PROBE’s regular paydays in accordance with the Company’s customary payroll practices. DR.MIMMS will not be entitled to any compensation of any kind whatsoever other than that expressly setforth in this Paragraph 2(a), provided, however, that he shall be entitled to any stock optionspreviously granted to him and vested as of the Resignation Date, in accordance with the terms ofthe applicable plans and agreements.          b. **Health Care and Life Insurance Coverage****.**GEN-PROBE shall provide DR. MIMMS withcontinued health care coverage under GEN-PROBE’s medical plan, without charge, to DR. MIMMS and hiseligible dependents until the earlier of (i) July 16, 2008 or (ii) the first date that DR. MIMMS iscovered under another employer’s health benefit program providing substantially the same or betterbenefit options to DR. MIMMS without exclusion for any pre-existing medical condition. The periodof time medical coverage continues under this agreement will be counted as coverage time underCOBRA. GEN-PROBE will pay the premium for continued life insurance coverage, if any, that DR.MIMMS may have elected under GEN-PROBE’s Life Insurance and Supplemental Life Insurance plan,subject to payment by DR. MIMMS of the portion of such premium not contributed by GEN-PROBE undersuch plan, through July 16, 2008.          c. **Transition Services****.**GEN-PROBE agrees to provide DR. MIMMS with transition supportservices during the first three months of the Salary Continuation Period. At DR. MIMMS’ option,GEN-PROBE agrees to provide DR. MIMMS, in lieu of such services, the sum of $5,000, minusapplicable taxes.
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          d. **No Other Consideration or Obligation****.**DR. MIMMS acknowledges and agrees that, uponperformance of this Agreement by GEN-PROBE, he will have been paid all salary, overtime, bonuses,vacation, commissions and other compensation and benefits earned or accrued during his employmentwith GEN-PROBE. DR. MIMMS expressly acknowledges that he is not entitled, pursuant to companypolicy, prior contracts, other agreements or otherwise, to any other payment, benefit orconsideration of any type whatsoever in connection with the termination of his employment withGen-Probe.          e. **Tax Matters.** All compensation described in this Paragraph 2 will be subject toGEN-PROBE’s collection of all applicable federal, state and local income and employment withholdingtaxes. DR. MIMMS specifically agrees, upon the advice of counsel, that he alone is and will befully responsible for the payment of any and all amounts any governmental or tax authorities mayclaim are due, if any, on the consideration paid to him pursuant to this Agreement. DR. MIMMSfurther acknowledges that GEN-PROBE is relying on, among other things, this specific promise inentering into this Agreement. DR. MIMMS agrees to release, indemnify and hold harmless GEN-PROBE,from any and all claims by DR. MIMMS or any local, state or federal government agency for anyunpaid taxes. Gen-Probe shall issue and file an IRS Form 1099 regarding payments under thisParagraph 2.     3. **General Release**.          a. In exchange for the consideration described herein, DR. MIMMS on his own behalf and onbehalf of his heirs and assigns, hereby voluntarily, completely and irrevocably releases anddischarges Gen-Probe, including Gen-Probe’s officers, directors, shareholders, employees,attorneys, insurers, agents, successors, assigns and all related representatives and organizations(all collectively referred to herein as “GEN-PROBE”), from any and all obligations, liabilities,claims and causes of action of any kind whatsoever, arising out of or related to DR. MIMMS’employment with GEN-PROBE or termination of that employment, including but not limited to, any andall claims or causes of action for wrongful termination, breach of contract, acting in bad faith,negligent or intentional infliction of emotional distress, negligent or intentionalmisrepresentation, negligent or intentional interference with contract or prospective economicadvantage, violation of any employment policies, defamation in any form, any discrimination on thebasis of race, sex, age, national origin, veteran status, mental or physical disability, religion,sexual orientation, pregnancy status, marital status and/or any other employment-related claim orcause of action brought under state or federal law or pursuant to any administrative proceedingstatutory claims.          b. DR. MIMMS understands that various state and federal laws prohibit employmentdiscrimination based on age, race, color, sex, religion, national origin, marital status, ancestry,handicap, disability, medical condition and other factors, and prohibits harassment of any sortbased on any of those factors. DR. MIMMS understands and agrees that by signing this Agreement, heis waiving (among other things) any rights he has or may have had to pursue any and all availableremedies against GEN-PROBE under these employment discrimination laws and/or any otheremployment-related causes of action, including, without limitation, claims arising under: the AgeDiscrimination in Employment Act as amended, 29 U.S.C. § 621 et seq.; Title VII of the Civil RightsAct of 1964, as amended by the Civil Rights
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Act of 1991, 42 U.S.C. § 2000 et seq.; the Civil Rights Act of 1866, 42 U.S.C. § 1981; the Family and Medical Leave Act of1993, 29 U.S.C. § 2601 et seq.; the Americans with Disabilities Act of 1990, 42 U.S.C. § 12101 etseq.; the False Claims Act , 31 U.S.C. § 3729 et seq.; the Fair Labor Standards Act, 29 U.S.C. §215 et seq., as well as claims under the California Fair Employment and Housing Act, Cal. Govt.Code § 12900 et seq.; or under the California Labor Code), known or unknown, existing or potential,with respect to DR. MIMMS’ employment with Gen-Probe.          c. This Release is intended to be interpreted as broadly as possible and to apply to any andall claims available to DR. MIMMS in any forum.          d. The release set forth above includes the waiver of all unknown Claims, including an expresswaiver of DR. MIMMS’ rights under California Civil Code section 1542, which provides:**A general release does not extend to claims which the creditor does notknow or suspect to exist in his favor at the time of executing therelease, which if known by him would have materially affected hissettlement with the debtor.**DR. MIMMS has read and understands section 1542, and agrees to waive all rights under section 1542.DR. MIMMS expressly agrees and understands that this Agreement shall apply to all unknown andunsuspected claims, despite the fact that he may later discover facts in addition to or differentfrom those which he now believes to be true.     4. **Older Workers’ Benefit Protection Act****.**This Agreement is intended to release anddischarge any claims by DR. MIMMS under the Age Discrimination and Employment Act. To satisfy therequirements of the Older Workers’ Benefit Protection Act, the parties agree as follows:          a. DR. MIMMS acknowledges that he has read and understands the terms of this Agreement.          b. DR. MIMMS acknowledges that he has been advised to consult with an attorney, if desired,concerning this Agreement and has received all advice he deems necessary concerning this Agreement.          c. DR. MIMMS acknowledges that he has been given 21 days to consider whether to enter intothis Agreement, and has taken as much of this time as he deems necessary to consider whether toenter into this Agreement.          d. For a seven day period following the execution of this Agreement, DR. MIMMS may revoke thisAgreement by delivering a written revocation to the following person: Diana R. De Walt, VicePresident, Human Resources, Gen-Probe Incorporated, 10210 Genetic Center Drive, San Diego, CA92121. This Agreement shall not become effective and enforceable until the revocation period hasexpired (the “Effective Date”).
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          e. DR. MIMMS acknowledges that he is entering into this Agreement freely and voluntarily andwithout coercion, duress, fraud or undue influence of any kind whatever.     5. **Promise Not to Prosecute**. DR. MIMMS agrees that he will not prosecute or allow tobe prosecuted on his behalf, in any court or other forum, whether state or federal, any claim ordemand of any type related to the matters released above, it being the intention of the partiesthat with the execution of this Agreement, except for the payments and benefits described in thisAgreement, GEN-PROBE will be absolutely, unconditionally and forever discharged of and from allobligations to or on behalf of DR. MIMMS and his successors. DR. MIMMS agrees that in the eventany released Claim is instituted by him or on his behalf, this Agreement shall constitute anaffirmative defense to such Claim sufficient to warrant the immediate dismissal, with prejudice, ofsuch Claim.     6. **No Pending Claims**. DR. MIMMS represents he has no pending claim with the EqualEmployment Opportunity Commission or Department of Fair Employment and Housing. To the extent suchclaims exist, DR. MIMMS will take all actions in his power to withdraw, effective upon signing thisAgreement, any and all allegations of wrongdoing made against GEN-PROBE filed with or reported toany governmental agency, including any and all claims submitted to the Department of FairEmployment and/or the Equal Employment Opportunity Commission.     7. **Unknown or Different Facts or Law**. DR. MIMMS acknowledges that he may discoverfacts or law different from, or in addition to, the facts or law he knows or believes to exist withrespect to a released claim. He agrees, nonetheless, that this Agreement and the releasescontained in it shall be and remain effective in all respects notwithstanding such different oradditional facts or law.     8. **Participation in Litigation**. DR. MIMMS agrees that he will not voluntarilyparticipate in, be a witness in, be a party to, or otherwise voluntarily involve himself in anypotential claim or litigation against GEN-PROBE. DR. MIMMS further agrees that he will notvoluntarily assist or encourage in any manner whatsoever any person, party, or litigant, in anyclaim, potential claim or action, against GEN-PROBE.     9. **Advice of Counsel**. DR. MIMMS and GEN-PROBE acknowledge and agree that they havebeen supplied with, have read and have had an opportunity to discuss the terms of this Agreementwith their respective legal counsel. Each party further warrants and agrees that he/it fullyunderstands the contents and effect of this document, approves and voluntarily accepts the termsand provisions of the Agreement with full knowledge of their significance, agrees to be bound bythe Agreement.     10. **Confidential Information**. DR. MIMMS agrees that during his employment he has hadaccess to confidential information. DR. MIMMS hereby agrees he is bound by the ProprietaryInformation and Inventions Agreement, he will not disclose any confidential information acquiredduring his employment to any other person or entity and will not use any confidential informationacquired during his employment in any manner detrimental to Gen-Probe’s interests.
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     11. **No Admission of Liability**. It is understood and agreed by the Parties that thisAgreement is not an admission of liability on the part of GEN-PROBE.     12. **No Assignment**. DR. MIMMS warrants and represents that he has not assigned ortransferred to any person any released matter or any right to any of the consideration provided byGEN-PROBE pursuant to this Agreement. Notwithstanding the above, the parties agree that DR. MIMMS’obligations under the Proprietary Information and Inventions Agreement survive this Agreement.     13. **Entire Agreement**. This Agreement contains the entire agreement between theparties with respect to DR. MIMMS’ employment with GEN-PROBE, the termination of such employment,and the other matters addressed in this Agreement. There are no collateral agreements, written ororal that are not contained in this Agreement. The parties acknowledge and agree that no promisesor representations were made to them which do not appear in this Agreement. This Agreement mayonly be modified by a written instrument signed by DR. MIMMS and GEN-PROBE.     14. **No Presumption Against Drafter**. DR. MIMMS agrees that this Agreement has beennegotiated and that no provision contained herein shall be interpreted against any party becausethat party drafted the provision.     15. **Severability**. Should a court determine that any term of this Agreement isunenforceable, that term shall be deemed to be deleted. However, the validity and enforceabilityof the remaining terms shall not be affected by the deletion of the unenforceable term.     16. **Arbitration**. Any controversy or dispute relating to, arising out of, or in anyway connected to any provision of this Agreement shall be finally resolved by final and bindingarbitration in accordance with this Paragraph by a single arbitrator who is a former state orfederal judge, to be conducted in San Diego, California. DR. MIMMS and GEN-PROBE waive any rightsto a jury trial in connection with such claims or disputes. Unless the parties agree otherwise,the arbitration shall be conducted by former state or federal judge appointed by the AmericanArbitration Association, or by any similar arbitration provider if AAA is no longer in existence orunable to appoint a former state or federal judge to serve as arbitrator. The costs of thearbitration, including the fees of the arbitrator, shall be borne exclusively by Gen-Probe. Thearbitrator’s decision shall be delivered in writing and shall disclose the essential findings andconclusion on which the arbitrator’s decision is based. The parties shall be permitted to conductadequate discovery to allow for a full and fair exploration of the issues in dispute in thearbitration proceeding. The arbitrator may grant any relief which otherwise would have beenavailable to the parties in a court proceeding. The decision and award of the arbitrator shall befinal and binding, and judgment upon the arbitrator’s award may be entered by any court ofcompetent jurisdiction.
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     17. **Counterparts**. This Agreement may be executed in counterparts and shall be bindingon all parties when each has signed either an original or a copy of this Agreement.**The parties acknowledge that they have read this Agreement carefully and fully understand each andevery provision contained herein, and intend to be bound by all of its terms.**       Dated: April 16, 2007 /s/ Larry T. Mimms         Larry T. Mimms, Ph.D.         Date: April 16, 2007 Gen-Probe Incorporated           By: /s/ Diana De Walt           Diana De Walt Vice President, Human Resources  
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