Exhibit 4.5


 


	NUMBER

C-	 	SHARES
	 	 	 
	 SEE REVERSE FOR CERTAIN DEFINITIONS	 	 
	 	 	 
	 	 	CUSIP _____


 


TANGO THERAPEUTICS, INC.


 


COMMON STOCK


 


THIS CERTIFIES THAT      
            is the owner of                   
fully paid and non-assessable shares of common stock, par value $0.001 per share (the “Common Stock”), of Tango
Therapeutics, Inc., a Delaware corporation (the “Company”), transferable on the books of the Company in person
or by duly authorized attorney upon surrender of this certificate properly endorsed.


 


 


This certificate is not valid unless countersigned
by the Transfer Agent and registered by the Registrar of the Company.


 


Witness the facsimile signature of a duly authorized
signatory of the Company.


 


	 	 	 
	Authorized Signatory	 	Transfer Agent


 



     


     


    







 


TANGO THERAPEUTICS, INC.


 


The Company will furnish without charge to each stockholder
who so requests, a statement of the powers, designations, preferences and relative, participating, optional or other special rights of
each class of equity or series thereof of the Company and the qualifications, limitations, or restrictions of such preferences and/or
rights. This certificate and the shares represented thereby are issued and shall be held subject to all the provisions of the Company’s
Second Amended and Restated Certificate of Incorporation and all amendments thereto and resolutions of the Board of Directors providing
for the issue of securities (copies of which may be obtained from the secretary of the Company), to all of which the holder of this certificate
by acceptance hereof assents.


 


The following abbreviations, when used in the inscription
on the face of this certificate, shall be construed as though they were written out in full according to applicable laws or regulations:


 


	TEN COM	—	as tenants in common	UNIF GIFT MIN ACT	—	 	 Custodian	 
	TEN ENT	—	as tenants by the entireties	 	 	(Cust)	 	(Minor)
	 	 	 	 	 	 	 	 
	JT TEN	—	as joint tenants with right of survivorship and not as tenants in common	 	under Uniform Gifts to Minors Act	 
	 	 	 	 	 	(State)	 


 


Additional abbreviations may also be used though not
in the above list.


 


For value received,                   
hereby sells, assigns and transfers unto


 


(PLEASE INSERT SOCIAL SECURITY OR OTHER IDENTIFYING
NUMBER(S) OF ASSIGNEE(S))


 


(PLEASE PRINT OR TYPEWRITE NAME(S) AND ADDRESS(ES), INCLUDING
ZIP CODE, OF ASSIGNEE(S))


 


shares of Common Stock represented by the within
Certificate, and hereby irrevocably constitutes and appoints


 


Attorney to transfer the said shares of Common Stock
on the books of the within named Company with full power of substitution in the premises.


 


Dated:


 


	 	 
	 	Notice: The signature(s) to this assignment must correspond with the name as written upon the face of the certificate in every particular, without alteration or enlargement or any change whatever.


 



     


     


    







 


	Signature(s) Guaranteed:	 
	 	 
	 	 
	THE SIGNATURE(S) MUST BE GUARANTEED BY AN ELIGIBLE GUARANTOR INSTITUTION (BANKS, STOCKBROKERS, SAVINGS AND LOAN ASSOCIATIONS AND CREDIT UNIONS WITH MEMBERSHIP IN AN APPROVED SIGNATURE GUARANTEE MEDALLION PROGRAM, PURSUANT TO S.E.C. RULE 17Ad-15 UNDER THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED (OR ANY SUCCESSOR RULE).