DEFENSE THREAT REDUCTION AGENCY 

8725 JOHN J. KINGMAN ROAD, STOP 6201 

FORT BELVOIR, VA 22060-6201 

Cliff Kincaid 

President, America's Survival, Inc. 

8221 Frances Lane 

Owings, MD 20736 

Re: FOIA Case No.: 20-041 

Dear Cliff Kincaid: 

February 17, 2022 

This is a final response to your Freedom of Information Act (FOIA) request perfected on 

May 4, 2020, and assigned FOIA case number 20-041 by the Defense Threat Reduction Agency 

(DTRA). You requested a copy of files, documents, or any material relating to Defense Threat 

Reduction Agency grants to the EcoHealth Alliance pertaining to Grant HDTRAl 1910033. 

Enclosed is a copy of documents totaling 59 pages. These records are being released to 

you in part. Some information is being withheld under FOIA Exemptions 4 and 6. 

Exemption 4 of the FOIA protects trade secrets and commercial or financial information 

obtained from a person that is privileged or confidential. The confidential commercial 

information withheld under Exemption 4 in the responsive documents is treated as private by 

Ecohealth. Ecohealth provided the commercial and financial information to DTRA under an 

assw-ance of confidentiality. 

Exemption 6 applies to information, which, if released, would constitute a clearly 

unwarranted invasion of the personal privacy of an individual. In this case, some individuals' 

names, salaries, personal email addresses, and cell phone numbers have been redacted due to 

security and privacy concerns. Those names do not directly reveal the operations of the federal 

government and therefore, fall outside the ambit of public interest that FOIA was enacted to 

serve. As a result, the privacy interest outweighs the public interest in those names. 

Determinations for this interim release were made by the Initial Denial Authority (IDA), 

Mr. Earl Washington, Chief, Records Management, FOIA, and Privacy Act Division/ DTRA 

Records Officer, Information Management and Technology Directorate, on behalf ofDTRA. If 

you consider this decision to be an adverse determination, you may file a written appeal that is 

postmarked no later than 90 calendar days after the date of this letter to the Deputy Director, 

Defense Threat Reduction Agency, Information Management and Technology Directorate, 

ATTN: FOWPA Office, 8725 John J. Kingman Road, MSC 6201, Fort Belvoir, Virginia 

22060. The appeal should reference the FOIA/Privacy Act case number, contain a concise 

statement of the grounds upon which the appeal is brought, and a description of the relief sought. 

A copy of this letter should also accompany your appeal. Both the envelope and your letter 

should clearly identify that a Freedom of Information Act and/or a Privacy Act Appeal is being 

made. 
Should you have additional questions or concerns regarding this case, you may seek 

dispute resolution services from the DTRA FOIA Public Liaison or the Office of Government 

Infonnation Services (OGIS). The DTRA FOIA Public Liaison, Mr. Mario Vizcarra, may be 

contacted by phone at (703)767-1792 or by email at dtrafoiaprivacy@mail.mil. The contact 

information for OGIS can be found at www.archives.gov/ogis. 

Enclosure( s): 

As stated 

2 

Sincerely, 

&upneMdJild 

Eugene McGirt 

FOIA/Privacy Act Specialist 

Freedom oflnformation/Privacy Act Office 
A~IENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT 11 cor-;TR,\CT 10 co DE 

I P~GE,HA;Es 

' A\11:NDMl:K J".'MOD11-JCAI10~ NO \.UH.:CIJVl:DAJI: .j Rl:()Ul~l-l[()N,n:RcHA~I: RU) NO _<_ PROJLC I NO lll,,ppl1ca~lci 

P00002 24-lvlar-2020 

1,. ISSllED BY CODE HDTRA1 ; i\D\1TNl~TERED B\ {[ln1lw1 IIM11 110111/,1 <ODE I N62879 OFFICE OF NAVAL RESEARCH-BOSTON 

DEFENSE THREAT REDUCTION AGENCY,AL-AC 495 SUMMER STREET, ROOM 152.7 8725JOHN J, KINGMAN ROAD. MSC 6201 BOSTON MA 02110-2109 

FORT BELVOIR VA22060-6al1 

8 /\"AME AND ADDRESS OJ· CONTRAlTOR (No .. ~irc~L Cow1ty. S!atc and Zip CodcJ 9A. A:VlloND:VIL\JT OF SOLICJrATIO:-J NO. 

ECOHEALTH ALLIANCE INC 

MR ALEKSEICHMURA 9B. DATEDCSEEITEM IIJ 460W 34TH ST 17TH FL 

NEW YORK NY 10001-2317 

X JOA :-..too. OF CO:-ITRACT/ORDER :-10. 

HDTRA 11910033 

!OB. DATED {SEE ITE:-..1 DJ 

CODE '<MMII'< I,, "' • " X 15-Aun-2019 

II Tl!IS ITEM 0:-IL Y APPLIES TO AME:-IDME:-ITS OF S.OLICIT A TIONS 

TI« .,h,,, <' n LI nl>cred ,nl,c ,1.,11 n11 , , ·""''"Jed ·" "" ,,rth l ll ltem l •l, TI\t lwll r ,.nd J,L<l' ,pc, Llitd "" rc,-e, pl l\l O Iler □ "e\knJed. D " not c,1cnded 

O!lc1 11ll"I ,,ck11nwk<l~e roco1p1 ol lhl' dlll:lHin>.'lll 1mnr1n tho lwu1 ,'1Hi ddlO ,1w,·1ti,•<I 111 1h,• ,nii,·11,'11n11 n1 •" ,'1n'IHk<I hy 011,• nflh,• o,1lnw111~ 1n-1hod, 

1,,1 !Jy t<>H\)iellll~ ]kn~ S ,tnd I<_ ,.nJ murn1ng ___ u,p,e, <>I the ,,11c1Hln~•nl. Jbi !Jy ,Ll·lno\\ lcclg1ng ,cct1pl <>I ,hi, ,Ll\cnJm,1H <><l l',L,h e<>py ol <he olk, ,ub,,.HcJ, 

or (cf lly ,cp.11alc k\Lc1 "' tdcgr,rn, wlmh '"cluJc, .1 rdcrmcc tu l11c ,ulicll,HHJH a"J .1m,uJ1m1t "unhcr, l·AlLUR!.: OI· \ OUR ACKKOl'i LLD(i.\11.:N-I JU Ill: 

RECEJVED A TTJIE PLACE D[.'>IGNA TED !'UR Tll[ RECEJPTOf. UffERS PRIOR TU TJIE JIULIR AND DA IT .'>P[C I fl ED .\1A Y R[.'>LIL T l',J 

REJE<TION OF YOllR OFFER [I h) ,·1t1uo nt1h1, ,'1n."1Hln.,111 you ,k,1r,• 1n ch,m~o .111 otter .1lro,l(I)' ,uh11u11ed. ,u,·h c·h.111~e 11"} h,• 11•Hk hy 1eker,11nn1 kt1er, 

pr,n 1dcd each tclcgramo1 kL1cr make, 1clCrencc to the ,olJ.·l1aL1on an,I 1h1, a1n·nd1ml1 and , , I CCLI \'L<I p, I 01 '" 1 be open Ing holil and dale ,pc,·, n«I 

12. ACCOt:NTl:-IG AJ\'D APPROPRIATI0:-1 DAT A {If required) 

See Schedule 

13. THIS ITEM APPLl!oSONL Y ro MOl)[FJCATIO:-JS OJ· CONTRAlTS/ORDLRS. 

IT MODIFIES THE CONTRACT/ORDER NO AS DESCRIBED IN ITEM 14 

A. TIIIS. CIIA:-IGE ORDER IS IS.SUED PURSUAJ\T TO: (Specify authority I Tl!E Cl!AJ\'GESSET FORTI! II\' ITEM 14 ARE MADE IN TI!E 

COT\TRACT ORDER NO IN ITEM IOA. 

u. THL Al.JOVE NUMl.lLRLD COi\" l"Ri\lTiORDLR JS MODil'ILD ro REJ-LLCI" THL ADJl.11:-JISTRAl"IVL CHANUES(,uch a, change, in payin_g 

office. annroo1iation date. etc.IS.ET FORTH IN ITE:-..114, PURSUANT TO T!IE AlTIIORITY OF FAR 43 103(Bl. 

C. Tl!IS SUPPLEMEJ\'T AL AGREEMEJ\T IS E:-ITERED INTO PURS.UA:-IT TO At:TIIORITY OF: 

X D. OT HER (Sp~cit'y type ,if modificat i,rn and authority I 

Terms & Conditions, Paragraph 5 rv'oditication of the Grant 

E. IMPORTANT Contractor GJ i, not, □ i, requi1ed to sign thi, document an<l return copies to the issuing office. 

" DESCRIPTIOJ\' OF AME:-IDME:-/TlMODIFICATIOJ\' {Organized by UCF ;ect ion heading,. including solicitation/cont1 act subject matter 

where teasihle I 

Modificati,rn Control Nwnbcr: robinson20960 

The purpose of this modification is to. 

(1) Corrtiine the scope and value from Option CLINs 0002, 0003, 0004, and 0005 into base CLIN 0001. 

(2) Extend the PoPof CLIN 0001 through August 18, 2024 at no addtional cost to the Government. 

(3) Update Grant RJC. 

(4) Update grant funding profile and invoice schedule. 

b:ccpt '" p1<>1 HkJ bcrrn1. ,,II !cm~ a[lJ CO[]JJlHJm <>I li1c Jocc11J~[]\ rcb ClltcJ L[l ltcm 9A or I IJA . .1, hcrt"l<>kJTc cb,rngcJ l ClLUHL, U[ldJ.JHgcJ .JJLJ L[l lull lo rec a[]J cilcct 

15A. NAML A:-J[) TITLL 01' SIUNER (Type lll' print) 16A. NA:.'1L i\]\"[) Tl l"LL OJ· CONTRACl"JJ\"UOl'l'ICER (Type lll' print) 

bl/61 I' CONTRACTING OFFICER 

TELKb)/6) I EMAIL Kb)/6) I 

l 'iB. COJ\TRACTOR'OFFEROR 15C. DATE S.IGNED 16B. fb~l~Ell '-I HES OE UIEIHC~ 16C. DATE S.IGNED 

I UY 24-lvlar-2020 

{Signature of pei:,,on authorize<l to ,ign 1 (Signatu1 e of Contracting Office1 l 

EXCEPTION TO SF 30 

APPROVED BY OIRM 11-84 

30-105-04 ~TANDARD FORM 30 (Re,, 10-83) 

Pr~,nibt:,d by GSA 

FAR t48 CFRJ 53.243 
SECTION SF 30 BLOCK 14 CO::-,./TI::-,./UATION PAGE 

StJM:\1ARY OF CHANGES 

SECTION A - SOLICIT ATIO:-.J/COI\TRACT FORM 

IIDTRAI 1910033 

P00002 

Page 2 of9 

The total cost of this contract was increased by $3,990,550.00 from $998.464.00 to 

$4,989,014.00. 

SECTION B - SUPPLIES OR SERVICES AND PRICES 

CLl:--.J 0001 

The unit price amount has increa~ed by $3,990,550.00 from $998-464.00 to $4,989,014.00. 

The unit of i~sue Lot ha~ been added. 

The total cost of this line item has increased by S3,990_550.00 from $998-464.00 to $4,989,014.00. 

CU:-,./ 0002 

The CU:-,./ extended description has changed from: 

Reducing th.: Threat of Rift Valley Fever through Ecology, Epidemiology. and Socio-Economics.In accordance with 

th.: following attachments: SOW at Exhibit A dated December 5,2018 and DTRA Term~ and Conditiom for Grant 

Awards. dated April 6, 2018 at Exhibit B. 

To: 

FOR MISSIO::-,./ CO::-,./TI::-,./UITY, THE SCOPE A::-,./D VALUE FROM CLIN 0002 HAS BEEi\" COMBI::-,./ED WITH 

CU:-,./ 000 I. THIS OPTIO::-,./ IS NOT TO BE EXERCISED. 

The pricing detail quantity ha~ decreased by 1.00 from 1.00 to 0.00. 

The total co~t of this line item ha~ decreased by $998.181.00 from $998.181.00 to S0.00. 

CLl:--.J 0003 

The CLl:--.J extended de~cription ha~ changed from: 

Reducing the Threat of Rift Valley Fever through Ecology, Epidemiology, and Socio-Economics.In accordance with 

the following attachments: SOW at Exhibit A dated December 5,2018 and DTRA Terms and Conditions for Grant 

Award~, dated April 6, 2018 at Exhibit B. 

To: 

FOR MISSIO::-,./ CO::-,./TI::-,./UITY, TIIE SCOPE A::-,./D VALUE FROM CLIN 0003 IIAS BEEi\" COMBI::-,./ED WITH 

CU:-,./ 0001. Tl !IS OPTIO::-,./ IS NOT TO BE EXERCISED. 
The pricing detail quantity has decreased by 1.00 from 1.00 to 0.00. 

IIDTRAI 1910033 

P00002 

Page 3 of9 

The total cost of this line item has decreased by $997.709.00 from $997.709.00 to SO.DO. 

CLl:-.J 0004 

The CLl:-.J extended de~cription ha~ changed from: 

Reducing the Threat of Rift Valley Fever through Ecology, Epidemiology. and Socio-Economics.In accordance with 

the following attachments: SOW at Exhihit A dated Decemher 5-2018 and DTRA Terms and Conditions for Grant 

Award~, dated April 6, 2018 at Exhibit B. 

To: 

FOR MISSIO:-.J CO:-.JTl:-.JUITY, THE SCOPE A:-.JD VALUE FROM CUN 0004 HAS BEEi\" COMBl:-.JED WITH 

CLl:-.J 0001. THIS OPTIO:-.J JS NOT TO BE EXERCISED. 

The pricing detail quantity ha~ decreased hy 1.00 from 1.00 to 0.00. 

The total co~t of this line item ha~ decreased hy $997,193.00 from $997,193.00 to $0.00. 

CLI:'.'J 0005 

The CLI:'.'J ext.::nded description has changed from: 

Reducing the Threat of Rift Valley Fever through Ecology, Epidemiology. and Socio-Economics.In accordance with 

the following attachments: SOW at Exhibit A dated December 5,2018 and DTRA Terms and Conditions for Grant 

Awards. dated April 6, 2018 at Exhibit 8. 

To: 

FOR MISSIO:-.J CO:-.JTl:-.JUITY, THE SCOPE A:-.JD VALUE FROM CUN 0005 HAS BEEi\" COMBl:-.JED WITH 

CLl:-.J 0001. THIS OPTIO:-.J JS NOT TO BE EXERCISED. 

The pricing detail quantity ha~ decreased by 1.00 from 1.00 to 0.00. 

The total co~t of this line item ha~ decreased hy $997,467.00 from $997,467.00 to $0.00. 

SUBCUI\" 000103 is added as follows: 
ITE:\1 NO SUPPLIES/SERVICES 

000103 

Funding for CL!!\" 0001 

FFP 

ACRN AC 

CIN: HDTRA\0343770001 

QUANTITY U::-,./IT 

SECTION C - DESCRIPTIOl\"S AND SPECIFICATIOl\"S 

The following have been modified: 

U::-,./ITPRICE 

:-,./ET AMT 

252.601-9002 GRANT REFERENCE INFORMATION (MAY 2009) 

IIDTRAI 1910033 

P00002 

Page 4 of9 

A:'vIOUNT 

S0.00 

SO.DO 

$3,990,550.00 

a. This grant is awarded as a result of Broad Agcncy Announcement (BAA) HDTRAl-14-24-

FRCWMD-BAA. Research and Dcvdopmcnt Entcrpri~c. Ba~ic and Applied Scicnccs Directorate. 

Ba~ic Rcscarch for Combating Weapons of :'vtass Destruction (C-W:'vID). 

b. CFDA #: 12.351 

c. Authority: 10 U.S.C. 2358 as amended 

SECTION E- 1:-.JSPECTION Al\"D ACCEPTA:-.JCE 

The following Acceptancelln~pection Schedule wa~ added for SUBCLl:-.J 000103: 

INSPECT AT INSPECT BY ACCEPT AT 

N/A NIA !\"IA 

SECTION F - DELIVERIES OR PERFORMANCE 

The following Delivery Schedule item for CUN 0001 ha~ heen changed from: 

DELIVERY DATE QL:AKTITY SI !IP TO ADDRESS 

ACCEPT BY 

:-.J/A 

DODAACI 

CAGE 
To: 

POP 19-AUG-2019 TO 

l 8-AL:G-2020 

DELIVERY DATE 

POP 19-AUG-2019 TO 

l 8-ALG-2024 

!\"/A 

!\"IA 

IIDTRAI 1910033 

P00002 

Page 5 of9 

DEFENSE THREAT REDUCTIO:'.'J 

AGENCY/CT-I 

/h1/R1 

8725 JOH!\" J. KINGMA!\" ROAD MSC 6201 

FORT BELVOIR VA 22060-6201 

j{b)(6) I 

FOB: De~tinat10n 

SHIP TO ADDRESS 

DEFENSE THREAT REDUCTIO:-.J 

AGENCY /CT-I 

b)(6) 

8725 JOI!!\' J. KINGMA!\' ROAD MSC 6201 

FORT BEL VOIR VA 22060-6201 

j{b)(6) I 

FOB: Destination 

HDTRAI 

DODAACI 

CAGE 

HDTRAI 

The following Delivery Schedule item for CUN 0002 has been changed from: 

DELIVERY DATE QL:Al\"TITY SHIP TO ADDRESS 

POP 19-AUG-2020TO !\"/A DEFENSE THREAT REDUCTIO:-.J 

l 8-ACG-2021 AGENCY/CT-I 

(b1(6) I 

8725 JOAN l KINC,MA~ ROAD MSC 6201 

FORT BELVOIR VA 22060-6201 

l(b)(6) I 

1:OB: De~tination 

To: 

DELIVERY DATE QL:Al\"TITY SI !IP TO ADDRESS 

POP 19-AUG-2020 TO !\"/A DEFENSE Tl IREAT REDUCTIO:'.'J 

l 8-AL:G-2021 AGENCY/CT-I 

(b)(6) 

8725 JOH!\" J. KINGMA!\" ROAD MSC 6201 

FORT BEL VOIR VA 22060-6201 

l(b)(6) 

FOB: Destmat10n I 

The following Delivery Schedule item for CUN 0003 ha~ been changed from: 

DELIVERY DATE QCAl\"TITY SHIP TO ADDRESS 

DODAAC/ 

CAGE 

HDTRAI 

DODAAC/ 

CAGE 

IIDTRAI 

DODAAC/ 

CAGE 
To: 

POP 19-AUG-2021 TO 

l 8-AL:G-2022 

DELIVERY DATE 

POP 19-AUG-2021 TO 

l 8-AL:G-2022 

!\"/A 

!\"IA 

IIDTRAI 1910033 

P00002 

Page 6 of9 

DEFENSE THREAT REDUCTIO::-,./ HDTRA I 

AGENCY/CT-I 

rb)(6) i 

8123 JUHi\ J. KINUIVIAI\ ROAD MSC 6201 

FORT BELVOIR VA 22060-6201 

i(b)(6) I 

FOB: De~tinat10n 

SHIP TO ADDRESS 

DEFENSE THREAT REDUCTIO:-.J 

AGENCY/CT-I 

b)(6) 

8725 JOI!!\" J. KINGMA!\" ROAD MSC 6201 

FORT BEL VOIR VA 22060-6201 

l(b)(6) I 

FOB: Destmat10n 

DODAACI 

CAGE 

HDTRAI 

The following Delivery Schedule item for CUN 0004 has been changed from: 

DELIVERY DATE QL:Al\"TITY SHIP TO ADDRESS DODAAC/ 

CAGE 

POP 19-AUG-2022 TO !\"/A DEFENSE THREAT REDUCTIO:-.J HDTRAI 

l 8-ACG-2023 AGENCY/CT-I 

b)(6) 

8725 JOH!\" J. KINGMA!\" ROAD MSC 6201 

FORT BELVOIR VA 22060-6201 

fb1(6) I 1.-()B: De~tmat1on 

To: 

DELIVERY DATE QL:Al\"TITY SI !IP TO ADDRESS DODAAC/ 

CAGE 

POP 19-AUG-2022 TO !\"/A DEFENSE Tl IREAT REDUCTIO:'.'J IIDTRAI 

l 8-AL:G-2023 8GEL!:l:CYlCI-I 

(b)(6) 

8725 JOH!\" J. KINGMA!\" ROAD MSC 6201 

FORT BEL VOIR VA 22060-6201 

l(b)(6) 

roo. oescmacmn I 

The following Delivery Schedule item for CUN 0005 ha~ been changed from: 
IIDTRAI 1910033 

P00002 

Page 7 of9 

To: 

DELIVERY DATE 

POP 19-AUG-2023 TO 

l 8-ACG-2024 

DELIVERY DATE 

POP 19-AUG-2023 TO 

l 8-ACG-2024 

QCAl\"TITY 

!\"/A 

!\"/A 

SHIP TO ADDRESS 

DEFENSE THREAT REDUCTIO::-,./ 

AGENCY/CT I 

b)(6) 

8725 JOH!\" J. KINGMA!\" ROAD MSC 6201 

FORT REI VOIR VA. 22060-6201 

fb)(6) I 

FOB: De~tinat10n 

SHIP TO ADDRESS 

DEFENSE Tl IREAT REDUCTIO:'.'J 

AGENCY/CT-I 

l(b)(6) k 

X/25 JOIII\ J. KINGMAI\OAD MSC 6201 

FORT BEL VOIR VA 22060-6201 

fb)(6) I 

run. oesnnatmn 

SECTION G- CO:-.JTRACT ADMl:-.JISTRATJON DATA 

Accounting and Appropriation 

Summary for the Payment Office 

DODAAC/ 

CAGE 

HDTRAI 

DODAACI 

CAGE 

IIDTRAI 

As a result of thi~ modification, the total funded amount for this document was increased hy S3,990550.00 

from $998,437.00 to $4,988,987.00. 

SUHCLIN 000103: 

Funding on SUHCLIN 000103 is initiated a~ follows: 

ACR:'.'J: AC 

Cl!\": HDTRAI0343770001 

Acctng Data: 0443150970134 000 :-.J 20202022 D 34000901515HR_KD_HP _TH_20 

2022_0134_3400_SCKCT DTRA 410 

Incrca~c: S3.990.550.00 

Total: $3,990,550.00 

The following have been modified: 

252.632-9000 GRA::-,./T FU::-,./Dl::-,./G PROFILE (MAR 2012) 
FUNDING PROFILE: 

The amount of $4,989,014 is obligated for work to be performed during the 

period beginning with grant award and continuing through August 18, 2024. 

The Government'~ liability is limited to the amount obligated. 

INVOICE SCHEDULE 

I 9/19/2019 $83,205.33 

2 10/19/2019 $83,205.33 

3 11/19/2019 $83,205.33 

4 12/19/2019 $83,205.33 

5 1/19/2020 $83,205.33 

6 2/19/2020 $83,205.33 

7 3/19/2020 $83,205.33 

8 4/19/2020 $83,205.33 

9 5/19/2020 $83,205.34 

10 6/19/2020 $83,205.34 

II 7/19/2020 $83,205.34 

12 8/19/2020 $83,205.34 

13 9/19/2020 $83, 8 .75 

14 10/19/2020 $83, 8 .75 

15 11/19/2020 $83, 8 .75 

16 12/19/2020 $83, 8 .75 

17 1/19/2021 $83, 8 .75 

18 2/19/2021 $83, 8 .75 

19 3/19/2021 $83, 8 .75 

20 4/19/2021 $83, 8 .75 

21 5/19/2021 $83, 8 .75 

22 6/19/2021 $83, 8 .75 

23 7/19/2021 $83, 8 .75 

24 8/19/2021 $83, 8 .75 

25 9/19/2021 $83,142.42 

26 10/19/2021 $83,142.42 

27 11/19/2021 $83,142.42 

28 12/19/2021 $83,142.42 

29 1/19/2022 $83,142.42 

30 2/19/2022 $83,142.42 

31 3/19/2022 $83,142.42 

32 4/19/2022 $83,142.42 

33 5/19/2022 $83,142.41 

34 6/19/2022 $83,142.41 

35 7/19/2022 $83,142.41 

36 8/19/2022 $83,142.41 

37 9/19/2022 $83,099.42 

38 10/19/2022 $83,099.42 

39 11/19/2022 $83,099.42 

40 12/19/2022 $83,099.42 

41 1/19/2023 $83,099.42 

42 2/19/2023 $83,099.42 

43 3/19/2023 $83,099.42 

44 4/19/2023 $83,099.42 

IIDTRAI 1910033 

P00002 

Page 8 of9 
45 

46 

47 

48 

49 

50 

51 

52 

53 

54 

55 

56 

57 

58 

59 

60 

(End of Summary of Change~) 

5/19/2023 

6/19/2023 

7/19/2023 

8/19/2023 

9/19/2023 

10/19/2023 

11/19/2023 

12/19/2023 

1/19/2024 

2/19/2024 

3/19/2024 

4/19/2024 

5/19/2024 

6/19/2024 

7/19/2024 

8/19/2024 

$83,099.41 

$83,099.41 

$83,099.41 

$83,099.41 

$83,122.25 

$83,122.25 

$83,122.25 

$83,122.25 

$83,122.25 

$83,122.25 

$83,122.25 

$83,122.25 

$83,122.25 

$83,122.25 

$83,122.25 

$83,122.25 

IIDTRAI 1910033 

P00002 

Page 9 of9 
A~IENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT 11 cor-;TR,\CT 10 co DE 

I P~GE,HA;Es 

' A\11:NDMl:K J".'MOD11-JCAI10~ NO \.UH.:CIJVl:DAJI: .j Rl:()Ul~l-l[()N,n:RcHA~I: RU) NO _<_ PROJLC I NO lll,,ppl1ca~lci 

P00001 27-Nov-2019 

1,. ISSllED BY CODE HDTRA1 ; i\D\1TNl~TERED B\ {[ln1lw1 IIM11 110111/,1 <ODE I N62879 OFFICE OF NAVAL RESEARCH-BOSTON 

DEFENSE THREAT REDUCTION AGENCY,AL-AC 495 SUMMER STREET, ROOM 152.7 8725JOHN J, KINGMAN ROAD. MSC 6201 BOSTON MA 02110-2109 

FORT BELVOIR VA22060-6al1 

8 /\"AME AND ADDRESS OJ· CONTRAlTOR (No .. ~irc~L Cow1ty. S!atc and Zip CodcJ 9A. A:VlloND:VIL\JT OF SOLICJrATIO:-J NO. 

ECOHEALTH ALLIANCE INC 

MR ALEKSEICHMURA 9B. DATEDCSEEITEM IIJ 460W 34TH ST 17TH FL 

NEW YORK NY 10001-2317 

X JOA :-..too. OF CO:-ITRACT/ORDER :-10. 

HDTRA 11910033 

!OB. DATED {SEE ITE:-..1 DJ 

CODE '<MMII'< I,, "' • " X 15-Aun-2019 

II Tl!IS ITEM 0:-IL Y APPLIES TO AME:-IDME:-ITS OF S.OLICIT A TIONS 

TI« .,h,,, <' n LI nl>cred ,nl,c ,1.,11 n11 , , ·""''"Jed ·" "" ,,rth l ll ltem l •l, TI\t lwll r ,.nd J,L<l' ,pc, Llitd "" rc,-e, pl l\l O Iler □ "e\knJed. D " not c,1cnded 

O!lc1 11ll"I ,,ck11nwk<l~e roco1p1 ol lhl' dlll:lHin>.'lll 1mnr1n tho lwu1 ,'1Hi ddlO ,1w,·1ti,•<I 111 1h,• ,nii,·11,'11n11 n1 •" ,'1n'IHk<I hy 011,• nflh,• o,1lnw111~ 1n-1hod, 

1,,1 !Jy t<>H\)iellll~ ]kn~ S ,tnd I<_ ,.nJ murn1ng ___ u,p,e, <>I the ,,11c1Hln~•nl. Jbi !Jy ,Ll·lno\\ lcclg1ng ,cct1pl <>I ,hi, ,Ll\cnJm,1H <><l l',L,h e<>py ol <he olk, ,ub,,.HcJ, 

or (cf lly ,cp.11alc k\Lc1 "' tdcgr,rn, wlmh '"cluJc, .1 rdcrmcc tu l11c ,ulicll,HHJH a"J .1m,uJ1m1t "unhcr, l·AlLUR!.: OI· \ OUR ACKKOl'i LLD(i.\11.:N-I JU Ill: 

RECEJVED A TTJIE PLACE D[.'>IGNA TED !'UR Tll[ RECEJPTOf. UffERS PRIOR TU TJIE JIULIR AND DA IT .'>P[C I fl ED .\1A Y R[.'>LIL T l',J 

REJE<TION OF YOllR OFFER [I h) ,·1t1uo nt1h1, ,'1n."1Hln.,111 you ,k,1r,• 1n ch,m~o .111 otter .1lro,l(I)' ,uh11u11ed. ,u,·h c·h.111~e 11"} h,• 11•Hk hy 1eker,11nn1 kt1er, 

pr,n 1dcd each tclcgramo1 kL1cr make, 1clCrencc to the ,olJ.·l1aL1on an,I 1h1, a1n·nd1ml1 and , , I CCLI \'L<I p, I 01 '" 1 be open Ing holil and dale ,pc,·, n«I 

12. ACCOt:NTl:-IG AJ\'D APPROPRIATI0:-1 DAT A {If required) 

See Schedule 

13. THIS ITEM APPLl!oSONL Y ro MOl)[FJCATIO:-JS OJ· CONTRAlTS/ORDLRS. 

IT MODIFIES THE CONTRACT/ORDER NO AS DESCRIBED IN ITEM 14 

A. TIIIS. CIIA:-IGE ORDER IS IS.SUED PURSUAJ\T TO: (Specify authority I Tl!E Cl!AJ\'GESSET FORTI! II\' ITEM 14 ARE MADE IN TI!E 

COT\TRACT ORDER NO IN ITEM IOA. 

u. THL Al.JOVE NUMl.lLRLD COi\" l"Ri\lTiORDLR JS MODil'ILD ro REJ-LLCI" THL ADJl.11:-JISTRAl"IVL CHANUES(,uch a, change, in payin_g 

office. annroo1iation date. etc.IS.ET FORTH IN ITE:-..114, PURSUANT TO T!IE AlTIIORITY OF FAR 43 103(Bl. 

C. Tl!IS SUPPLEMEJ\'T AL AGREEMEJ\T IS E:-ITERED INTO PURS.UA:-IT TO At:TIIORITY OF: 

X D. OT HER (Sp~cit'y type ,if modificat i,rn and authority I 

DTRA Terms and Conditions section 5 

E. IMPORTANT Contractor □ i, not, □ i, requi1ed to sign thi, document an<l return copies to the issuing office. 

" DESCRIPTIOJ\' OF AME:-IDME:-/TlMODIFICATIOJ\' {Organized by UCF ;ect ion heading,. including solicitation/cont1 act subject matter 

where teasihle I 

Modificati,rn Control Nwnbcr: lyles20269 

lncrem;,ntal funding of $436.10 

b:ccpt '" p1<>1 HkJ bcrrn1. ,,II !cm~ a[lJ CO[]JJlHJm <>I li1c Jocc11J~[]\ rcb ClltcJ L[l ltcm 9A or I IJA . .1, hcrt"l<>kJTc cb,rngcJ l ClLUHL, U[ldJ.JHgcJ .JJLJ L[l lull lo rec a[]J cilcct 

15A. NAML A:-J[) TITLL 01' SIUNER (Type lll' print) 16A. NA:.'1L i\]\"[) Tl l"LL OJ· CONTRACl"JJ\"UOl'l'ICER (Type lll' print) 

l 'iB. COJ\TRACTOR'OFFEROR 

{Signature of pei:,,on authorize<l to ,ign 1 

EXCEPTION TO SF 30 

APPROVED BY OIRM 11-84 

bl/61 

TEL Kb)(6) 

15C. DATE S.IGNED 16B. 

b)(6) 

UY 

I 1gnatu1e o 

30-105-04 

I 

CONTRACTING OFFICER 

EMAIL fb)(6) I 

ontradrng 1ce1 l

16C. DATE S.IGNED 

27-Nov-2019 

~TANDARD FORM 30 (Re,, 10-83) 

Pr~,nibt:,d by GSA 

FAR t48 CFRJ 53.243 
SECTION SF 30 BLOCK 14 CO::-,./Tl::-,./UATION PAGE 

StJM:\1ARY OF CHANGES 

SECTION G- CO:-.JTRACT ADMl:-.JISTRATJON DATA 

Accounting and Appropriation 

Summary for the Payment Office 

IIDTRAI 1910033 

P0000I 

Page 2 of2 

As a result of thi~ modification, the total funded amount for this document was increased hy S436.10 from 

S998,000.90 to S998.437.00. 

SUBCLIN 000 I 02: 

AB: 0443 I 5 097 on4 000 :-.J 20192021 D 34000901515BR KD_BP _TB_l 9 192 I_0n4_3400_SCNCT 

DTRA 410 (Cl:-.J HDTRA I 9312200001 J was increased hy $436.10 from S996,413.90 to $996,850.00 

The following have be.::n modified: 

252.601-9000 GRA::-,./T POI::-,./TS OF CONT ACT (:\IA Y 2009) 

a. Grant Sp.::ci0a,-li~st 7, __ ~ 

Name: ctb~ll~61_~~ 

Defense Threat Reduction Agency/AL-ACC 

8725 John J. Kingman Road. MS 6201 

Fort Belvoir. VA 22060-6201 

telephone j{bJ(6) 

email add1 

~----------~ 

h. Grantee Busine~~ Office: 

Name: 

Title: 

Phone: 

Dr. Aleksei Chmura 

Authorized Organizational Representative 

(212) 380-4473 

E-mail: chmura@lccohcalthalliancc .or»: 

c. Grante.:: Principal Investigator (Pl): 

Name: Dr. William Kar.::sh 

Tille: Ex.::culive Vice Prc~id.::nl of Ilcallh and Policy 

Phone: (212) 380-4463 

E-mail: karesh (o'lecuheal tha II i ance .org 

(End of Summary of Changes) 
AWARD/CONTRACT I TIIIS. CONTRACf IS. A RATED ORDER IM.TING PAGE OF PAGES 

ll:'-IDER DPAS( 15 CFR 700) 1 I '" 

7 CONTRACT ·f"" 1,,,, M-,,, NO. J EHLCTIVL DATE 14 REQU!Sl l'ION/PURCHASL REQUiST/PROJElT NO. 

HDTRA11910033 15 Aug 2019 

5 ISS.UED BY CODE HDTRA1 6. ADMIJ\'ISfERED BY (//01/", !/J"" /1rn, _\) CODEIN62879 

DEFENSE THREAT REDUCTION AGENCY/AL-AC OFFICE OF NAVAL RESEARCH-BOSTON 

8725JOHN J KINGMAN ROAD. MSC 6201 495 SUMMER STREET. ROOM 627 

FORT BELVOIR VA22060-6201 BOSTON MA 02110-2109 

7 ]\'AME A:-1D ADDRESS.OF COJ\TRACTOR , •Vo ,1,cc!., '" '"''""· '""'' ,md.q,,od,, 8. DELIVLRY 

ECOHEALTH ALLIANCE INC I I FOB ORICilN I XI OTHER \cc/"/""' 

MR. ALEKSEI CHMURA 

460W34TH ST 17TH FL 7 OISC011NTFOR PROMPT P ,\ 'l' \.1E:-.T 

NEW YORK NY 10001-2317 

10 SLBMITINVOIC'ES lrU1 

I./ , oj'ln 11'11, " od,e,·,, ,,,. •1>c,1/1<d1 

TOTHE,\r>DRESS 

CODE 3MMlJ3 IFACILITY CODE ~HOW',J l's 

11 SHIP TO/JVIARK FOR COOL IHDTRAI 12. PAYMENT WILL BE MADE BY COOL H00337 

DEFENSE THREAT REDUCTION AGENCY.'CT-I DFAS COLUMBUS CENTER 

b)(6) I DFAS-CO·NORTH ENTITLEMENT OPERATIONS 

OADMSC6201 eo BOX IS2317 

FORTBELVOIR VA22000-6201 COLUMBUS OH 43218-2317 

13. AUTHORITY FOR USI:--IG OTHER THAN FULL AND OPEN 14 ACCOUNTIT\'Ci A'\/D APPROPRIATION DAT A 

COMPETITI0:--1: See Schedule 

I I 10 t:.S.C. 2304(c)( I I I 41 USC. 253{c)( I 

15A. ITE:-.1 J\"O. 158. Sl_lPPLIES/ SER'vlCES 15C. QUANTITY 15D. llNIT I SE. UNIT PRICE 15F. A:-.10UNT 

SEE SCHEDULE 

15C. TOTAL AM0 1JNTO fl ''0'\/lRA''T 41::4_ 

16. TABLE m cor,;rLNTS 

Xl ISEC. I DESCRIPTIOJ\' IPAGE 1S 'X\ I SEC. I DESCRIPTIOJ\' IPAGE S 

r, , ... ,.,., - 'l'LIT,'_',J . ,, • y ' 01,:..-ro so 1 I ' ' r, I 

X B Sl:PPI.IES OR SFR\-1CES AND PRICES' cosrs 2 - S PART 111- LISTOF 001:1}ME."'fl"S EXHIBJTI, AND OTHER ATTACH. 

X 1: DF~"RIPTION/ SPEC~/ WORK ~'T ATFMFNT Io X I I l.l~T OF A TT ,V:HMFNTS I 12 

D PACKAUI'\/G AJ\'D J\1ARKING PART IV - RIPR.l!.~El\l,\'llO ',/S Al\D J',/S'!RllC'JlO ',/S 

X E l'\/SPECTION Al\'D ACCEPT A'\/CF 7 REPRESE:--IT ATIOJ\'S. CERTIFICATIONS AJ\'D 

V s DELIVERILSOR PERl'ORMA'\/CL ' 

K ...... - y r, '"O . "\ 0\1,-.,,TA ". 11 ' ro, >NOT 0 0 

H SPECIAL CONTRACT REQUIRFMFT\TS M EVALUATI0:--1 FACTORS FOR AWARD 

CO',JTRA( Tl',JG Off]( [R WILL COMPLETE ITE.\1 17 1S[ALED-lllll OR NEGOTJA ITD PRUCLIRE.\1E',JT1 OR IS 1SEAL[LJ-lll[) PRO( UR[ME'-JTi AS APPLICABLE 

'" I ( O.~ llt-\(TOR \ ~hGOJ"IAl~D ,\(;lth~Ml-.~ I ('01111,,c 1m" 1c'<J"IOC'1i tn "'° th" " I \h,\l.~Jl-BID ,\W.\l{l) I (\,nll«, 0>, " ll<>l LC~UU Cd <,> ''"" ,h,-dDcUnlc'lll I d,,c um, nl .i1d L'1<1I <> .->pee·,'" """"~ <>tloc,• ' Cm11",ctn, ,<ice·,·, tn l11n11,h ,inJ J,·ll'n ,,II '""' l•,d '"' ~"h'"·"""' r-;,,,,,bc, """"'"I"'' Im,,, .,II <he ,m ,ce, "'' lrnLh "' 1>1hcrn '" ,d,m,locd .,b"" .rnd "" "'" c'""""'·"""' 

,hcch i<'I ,h,· ,,>1Nd,·rnL11•n •Uls°d hc1,111 Th,· n;hl• ,11d ol,l,;,m,n,ol 1hc I'"'"'',,, lh1, 

'"""·'c 1 ,h., II he ,nbF, I LD .uni Z"""'"l b) II,c IDIID~ "'~ ,I,,,""'""" •,,,, 11"'·'"·"'1'"""·"' o11cludmc• tl1' ,dd,Ln>11' '""·"'C'' m ,de' b) < DU \\ h,-11 «Jd,L«>lh ,>, , I1.n>ic, ,,LC ,e< l<>L tl1 1'1 toll ., h,>IC "herd,) «ccc'i\lc•U •" 

IhJLl1c•"'l,uL,Lmn ,I'") ,ulJ I c , ,u,11 J" I'\ N<>l1' , ,•prc•,c,)l,11,'lh. cc,L,l I, ,L,<>lh ,u1J ,pculoc,,Lm<>• l•> th,· t,·m,, lhl('(I ,,h,n,· ,,nJ n11 .,11,· cnntI11,,.,1I"11 ,h,·,·h Th,, •'"·'"I, mhumm,it,·, Ilw, ,mt,,<cl "h" h '"'"''" ,,1 Ilw 

·" ,,LC ,dl.c hc'U DL llk<>I p,>, ,,L,•d h) LC Lrn nee' hrn 1'1 h>ll<>l'<ll1 J,cU"1c'llh' ... ,·. Llk' (;1\\c'Llll\lC<>t, "'lul,Ln,n .,nd) <>LIL hIJ .i1d lhJ u, .. .IC.LJ,.->,)ll.,c{ ~-' Lurlhc'I ""'"·"'"·,I 

IA11.,clrn,,n<,.uc lh<cdhc,cm, J,,,·unh'llll• lk'c','"•"'' , HJ,,c·~ I~ •hould l,c ,·h,·,·L:d 1•nl) "h,·11 ,l'<,,id111_, ., ,,,,hi hid ,<>I11I,,c•, 1 

I '>A. NAME AND TITLE OF SIG\IER I l>J!<'Ol"/'l·i1ll) 20A. NAME OF CONTRACTI\IG OFFICER 

(b)(6) I 'X+JJ:~\(_Jt+~ •jH'J ;u 

m.,1(b)(6) I r.t-'" lT ,fb)(6) 

19B. NAME OF CO:--ITRACTOR I 9C. DATE SIGNED 20B. TJ'\JJTFD SI ATF'-OF .i\1FRIC4 

I 

20C. DATE SIGNED 

r)(6) 

15-Aug-2019 

BY BY 

11,eu,,w,· 01 I"'""' ,,,,,!u,,ud '" """1 1\,e,•omn•,,/(;H,t,0,1'1,,C,()f'i,,•,, 

,\l I IJORU!-.D H/R L()( ,\L RJ-.l'R()l)llCIJO~ 
Section B - Supplies or Services and Prices 

ITEM 1\0 SCPPLIES/SERYICES QUA:-.JTITY 

I 

UNIT UNIT PRICE 

0001 S998,464.00 

YEAR I: FRBAA 14-6-2-0333 

FFP 

Reducing the Threat of Rift Valley Fever through Ecology, Epidemiology. and 

Socio-Economics. 

In accordance with the following attachments: SOW at Exhihit A dated Decemher 

5,2018 and DTRA Terms and Conditions for Grant Award~, dated April 6, 2018 at 

Exhihit B. 

FOB: Destination 

NET AMT 

ITEM 1\0 SLPPLIES/SERYICES QUA:-.JTITY UNIT UNIT PRICE 

000101 

Funding for CUN 0001 

FFP 

ACRI\ AA 

Cl!\: HDTRAI 931459000 I 

NET AMT 

IIDTRAI 1910033 

Page2ofl2 

AMOCI\T 

$998,464.00 

$998.464.00 

AMOLI\T 

S0.00 

SO.OU 

$1,587.00 
ITEM l\"O SL:PPLIES/SERVICES QUA::-,./TITY UNIT UNIT PRICE 

000102 

Funding for CUN 0001 

FFP 

ACRI\" AB 

CI!\": HDTRAl9312200001 

NET AMT 

ITEM 1\0 SCPPLIES/SERVICES QUA:-.JTITY 

I 

UNIT UNIT PRICE 

0002 S998, 181.00 

OPTION YEAR 2: FRBAA 14-6-2-0333 

FFP 

Reducing the Threat of Rift Valley Fever through Ecology, Epidemiology, and 

Socio-Economics. 

In accordance with the following attachments: SOW at Exhihit A dated Decemher 

5,2018 and DTRA Terms and Conditions for Grant Award~, dated April 6, 2018 at 

Exhihit B. 

FOB: Dc~linatiun 

NET AMT 

IIDTRAI 1910033 

Page 3 of 12 

AMOL:l\"T 

SO.DO 

SO.OU 

$996.413.90 

AMOCI\T 

$998,181.00 

$998,181.00 
ITEM l\"O SL:PPLIES/SERVICES QUA::-,./TITY 

I 

UNIT UNIT PRICE 

0003 S997,709.00 

OPTION YEAR 3: FRBAAl4-6-2-0333 

FFP 

Reducing the Threat of Rift Valley Fever through Ecology, Epidemiology. and 

Socio-Economics. 

In accordance with the following attachments: SOW at Exhibit A dated December 

5.2018 and DTRA Terms and Conditions for Grant Award~, dated April 6. 2018 at 

Exhibit B. 

FOB: Destination 

NET AMT 

ITEM l\"O SLPPLIES/SERVICES 

0004 

QUA:-.JTITY 

I 

UNIT UNIT PRICE 

S997,193.00 

OPTION YEAR 4: FRHAAl4-6-2-0333 

FFP 

Reducing the Threat of Rift Valley Fever through Ecology, Epidemiology, and 

Socio-Economic~. 

In accon.lanc.:: with the following allachmenb: SOW at Exhibit A dat.::d D.::cember 

5.2018 and DTRA Term~ and Conditiom !"or Grant Awards, dat.::d April 6. 2018 at 

Exhibit B. 

FOB: De~tinatiun 

NET AMT 

IIDTRAI 1910033 

Page4of 12 

AMOL:l\"T 

$997.709.00 

$997.709.00 

AMOLl\"T 

$997,193.00 

$997,193.00 
ITEM l\"O SL:PPLIES/SERVICES 

0005 

QUA::-,./TITY 

I 

UNIT UNIT PRICE 

S997,467.00 

OPTION YEAR 5: FRBAAl4-6-2-0333 

FFP 

Reducing the Threat of Rift Valley Fever through Ecology, Epidemiology. and 

Socio-Economics. 

In accordance with the following attachments: SOW at Exhibit A dated December 

5.2018 and DTRA Terms and Conditions for Grant Award~, dated April 6. 2018 at 

Exhibit B. 

FOB: Destination 

NET AMT 

IIDTRAI 1910033 

Page 5 of 12 

AMOL:l\"T 

$997.467.00 

$997.467.00 
IIDTRAI 1910033 

Page6ofl2 

Section C - Descriptions and Specifications 

CLAUSES INCORPORATED BY FL:LL TEXT 

252.601-9002 GRANT REFERENCE INFORMATION (MAY 2009) 

a. Thi~ grant i~ awarded a~ a re~ult of Broad Agency Announcement (BAA) HUT RA 1-14-24-

FRCWMD-UAA, Re~earch and Development Enterprise, Basic and Applied Sciences Directorate, 

Basic Re~earch for Comhating Weapon~ of :\fa~~ De~truction (C-W:\1D). 

b. CFDA #: 12.531 

c. Authorit~,: 10 U.S.C. 2358 as amcndcd 
Section E - Inspection and Acceptance 

INSPECTION AND ACCEPTANCE TERMS 

Supplies/services will be inspected/accepted at: 

CLl:-.J 1:-.JSPECT AT 11\"SPECT HY 

0001 Destination Government 

000101 :'.'JIA KIA 

000102 :'.'JIA KIA 

0002 Destination Government 

0003 Destination Government 

0004 Destinntion Government 

0005 Destination Government 

ACCEPT AT 

D.::stination 

NIA 

NIA 

D.::stination 

D.::stination 

Destination 

Destination 

IIDTRAI 1910033 

Page 7 of 12 

ACCEPT HY 

Governm.::nt 

NIA 

NIA 

Governm.::nt 

Governm.::nt 

Government 

Government 
IIDTRAI 1910033 

Page 8 of 12 

Section F - Deliveries or Performance 

DELIVERY INFORMATION 

CLI::-,./ DELIVERY DATE QL:Al\"TITY SHIP TO ADDRESS DODAACI 

CAGE 

0001 POP I9-AUG-2019 TO !\"IA DEFENSE THREAT REDUCTIO:-.J HDTRAI 

l 8-ACG-2020 AGENCY/CT-I 

(b)(6) 

8725 JOH!\ J. KINGMA!\ ROAD MSC 6201 

FORT BELVOIR VA 22060-6201 

b)(6) 

FOB: De~tination 

000101 :-.JIA !\IA NIA NIA 

000102 :-,./IA !\"IA NIA NIA 

0002 POP 19-AUG-2020 TO !\"IA DEFENSE Tl IREAT REDUCTIO:'.'J IIDTRAI 

l 8-AL:G-2021 

rb)(s!:::::~ ~IN OMAK Ju AD MSC 620 I 

EQRI BEi VQTR VA 22060-6201 

llb)(6) I 

FOB: Destination 

0003 POP 19-AUG-2021 TO !\"IA (SAME AS PREVIOUS LOCATION) HDTRAI 

l 8-ACG-2022 FOB: De~tination 

0004 POP I9-AUG-2022 TO !\IA (SAME AS PREVIOUS LOCATION) HDTRAI 

l 8-ACG-2023 FOB: De~tination 

0005 POP 19-AUG-2023 TO !\IA (SAME AS PREVIOUS LOCATION) HDTRAI 

l 8-ALG-2024 1:OB: De~tination 
IIDTRAI 1910033 

Section G - Contrnct Administrntion Data 

ACCOUNTING AND APPROPRIATION DAT A 

AA: 04431.'i 097 0134 000 l\ 20182020 D 34HQ 0<J0l.'il.'iBR_KD_BP _OT_l 8 1820_0134_34HQ_SCNCT DTRA 410 

AMOUNT: $1..587.00 

AB: 04431.'i 097 0134 000 l\ 20192021 D 3400 0<J0l.'il.'iBR_KD_BP _TB_l'l l'l21_0134_3400_SC!\CT DTRA 410 

AMOUNT: $9%,413.90 

ACRN CL!l\/SLl'.'J CIN 

AA 000101 

AB 000102 

HDTRA 19314.590001 

l!DTRAl931:?.:?.0000I 

CLAUSES INCORPORATED BY REFERENCE 

252.232- 7007 Limitation Of Gov.::rnmcnl's Obligation 

CLAUSES INCORPORATED BY FL:LL TEXT 

252.601-9000 GRA::-,./T POI::-,./TS OF CONT ACT (:\IA Y 2009) 

d. Grant Specia~l~is 7t~---, 

Name: K~b~)(~6)~---~ 

Defense Threat Reduction Agency/ AL-A CC 

8725 John J. Kingman Road. MS 620 I 

Fort Belvojr VA 22060 6201 

telephon1(b)(B) 

email ad1 

~-----------~ 

Grantee Husine~~ Office: 

Name: Dr. Aleksei Chmura 

A:VtOUNT 

$1,587.00 

$996,413.90 

Title: 

Phone: 

Authorized Organizational Representative 

(212) 380-4473 

E-mail: chmura@ccoh.::althallianc.::.org 

f. Orantes: Principal Investigator (Pl): 

Name: Dr. William Kar.::sh 

Title: Ex.::cutivc Vice Prc~i<l.::nl of llcalth and Policy 

Phone: (212) 380-4463 

E-mail: karesh (o'lecuheal tha II i a nee .org 

APR 2014 

252.601-9001 GRA:'HS OFFICER'S REPRESENTATIVE (GOR) (:V1A Y 2009) 

Page 9 of 12 
g. Grants Officer's Re resentative GOR) for this Grant is: 

Name: (b)(6l ·~-----~ Defense Threat Reduction Agency/BTRP 

8725 John J. Kingman Road. MS 620 I 

Fort Belvoir. VA 22060-620 I 

telephone b)(6) 

email add 

b. SCOPE AND LIMITATIO:-.JS OF ACTHORJTY FOR DTRA GRANTS OFFICER'S 

REPRESENTATIVE 

IIDTRAI 1910033 

Page 10 of 12 

I. The Grant~ Officer\ Representative (GOR) is respon~ihle for monitoring the technical and 

programmatic performance of the grant or cooperative agreement (hereinafter referred to as agreement) 

including compliance with the agreement's reporting requirements. Perceived deviation~ from the 

agreement's terms and conditions ~hal I he brought to the attention of appropriate recipient personnel and if 

nol corrected. to lhc allention of lhc Granls Officer. Deviatiom or other occum:nces indicative of the 

recipient's inability or unwillingnes~ to conform to lhe agreement\ requiremenb shall be broughl lo the 

immediate allenlion of lhe Granb Officer. 

2. The GOR ha~ no authority lo modify lhc stated terms of the agrecmenl or specifications in any manner, 

or to approve any action that would result in additional charges to the Government. The DTRA Grants 

Officer must make all such changes in writing. 

3. The GOR is authorized lo conc~pond direclly with lhe recipienl on mailer~ within lhe scope and 

limitalions of his or her authority. All such conc~pondcnce ~hall be signed personally by lhe GOR and a 

copy will be furnished the Grants Officer for placement in lhe official agreement file. 

4. The GOR will provide technical advice to the recipient to the extent such advice will not alter any of 

the agreement's terms and conditions or result in an increase in the estimated cost of the agreement's 

performance as specified in the agreement. The GOR is encouraged to discuss with the recipient new ideas 

related to the original scope of the agreement that may be of special interest to DTRA. The GOR should 

abo be alert for indications that any part of the research is becoming unfruitful. If, as a result of such 

discus~ions. questions ari~e a~ to the po~~ible need for a modification. the matter ~hall be brought to the 

immediate attention of the Grants Officer. The GOR shall not direct the recipient to undertake any action 

that the recipient believes to be contrary to the agreement\ scope, terms or conditions without the written 

approval of the Grant~ Officer. 

5. Any visits to the recipient's facilities on matters pertaining to the agreement will he documented in a 

brief memorandum. A copy will he provided the Grant~ Officer for placement in the official agreement 

file. 

6. The GOR \viii maintain ~uch \Vork files as he or ~he deem~ nece~sary to properly document 

performance of the duties and respon~ihilitie~ a~ a GOR. Upon completion of the agreement and delivery 

of all required reporls, ~uch work files will be forwarded lo the Granl~ Officer for placement in the official 

agreement file. 

7. In performance of the GO R's dulies, lhe GOR ~hall constantly stress proleclion of lhe Government's 

interests. Similarly, the GOR shall avoid any acl which may tend to compromise lhc position of DTRA, 

any individual member of DTRA or which will impact confidence in the integrity of DTRA with the 

business community. 

(End of Clause) 
IIDTRAI 1910033 

Pagellofl2 

252.632-9000 GRA::-,./T FU::-,./Dl::-,./G PROFILE (MAR 2012) 

FUNDING PROFILE: 

The amount of $998,000.90 is obligated for work to be performed during the 

period beginning with grant award and continuing through August 18. 2020. 

Additional incremental funding planned, but not obligated. is: 

FY19 5463.10 

The Government'~ liability is limited to the amount obligated. 

INVOICE SCHEDULE 

I 9/19/2019 $83.205.33 

2 10/19/2019 $83.205.33 

3 11/19/2019 $83.205.33 

4 12/19/2019 $83.205.33 

5 1 /I 9/2020 $83.205.33 

" 2/19/2020 $83.205.33 

7 3/19/2020 $83.205.33 

8 4/19/2020 $83.205.33 

9 5/19/2020 $83.205.34 

10 6/19/2020 $83.205.34 

II 7/19/2020 $83.205.34 

12 8/19/2020 $83.205.34 
Section J - List of Documents, Exhibits and Other Attachments 

Exhibit/ Attachment Table of Contents 

DOCLMENT TYPE 

Exhibit A 

Exhibit B 

DESCRIPTIOI\" 

Slalcmcnl of Work 

DTRA T .::nns and 

Conditions 

PAGES 

6 

18 

DATE 

05-DEC-2018 

06-APR-2018 

IIDTRAI 1910033 

Page 12of 12 
Revised 6 April 20 l 8 EXHIBIT B 

DEFENSE THREAT REDUCTION AGENCY (DTRA) 

GENERAL TERMS AND CONDITIONS FOR GRANT AWARDS 

Table of Contents 

Table of Contents .................................................................................................................... 1 

1. Terms and Conditions Incorporated by Reference ................................................. 2 

2. Acceptance of Grant ................................................................................................... 2 

3. Recipient I{esponsibilities ........................................................................................... 2 

4. Standards for Financial Management Systems ........................................................ 2 

5. Modification of the Grant. ......................................................................................... 2 

6. Payments ...................................................................................................................... 3 

7. Funding Increments and/or Options ......................................................................... 3 

8. Patent I{ights ............................................................................................................... 4 

9. Technical Reporting Requirements ........................................................................... 7 

10. Financial Reporting Requirements ......................................................................... 10 

11. Delegation of Administration Duties ....................................................................... 10 

12. Security ...................................................................................................................... 11 

13. Representations and Assurances ............................................................................. 11 

14. Data Collection .......................................................................................................... 16 

15. Publications and Acknowledgement of Sponsorship ............................................. 16 

16. Authorization to Perform Activities Abroad .......................................................... 17 

17. Inconsistency between English Version and Translation of Grant ...................... 17 

18. Value Added Tax (VAT) and Other Taxes .............................................................. 17 

Pagelofl8 
Revised 6 April 20 l 8 EXHIBIT B 

1. Terms and Conditions Incorporated by Reference. 

The DoD Research and Development General Terms and Conditions. dated July 2016, are 

hereby incorporated by reference and are available for download at website 

http:// w w w. onr. navy.mil/Con tracts-Gran ts/ submit -proposal/ grants-proposal/grants- termscondi ti ons. asp x. 

2. Acceptance of Grant. 

The recipient is not required to countersign the Grant document; however, the recipient 

agrees to the conditions specified in the Research Grant and the Articles contained herein 

unless notice of disagreement is furnished to the Grants Officer within fifteen ( 15) calendar 

days after the date of the Grants Officer's signature. In case of disagreement, the recipient 

shall not assess the Grant any costs of the research unless and until such disagreement(s) is 

resolved. 

3. Recipient Responsibilities. 

The recipient will bear primary responsibility for the conduct of the research and will 

exercise judgment towards attaining the stated research objectives within the limits of the 

Grant's Terms and Conditions. 

The Principal Investigator(s) (Pl) specified in the Grant award will be continuously 

responsible for the conduct of the research project and will be closely involved with the 

research effort. The PI, operating within the policies of the recipient, is in the best position to 

determine the means by which the research may be conducted most effectively. 

4. Standards for Financial Management Systems. 

Where the Federal Government guarantees or insures the repayment of money borrowed by 

the recipient. DTRA, at its discretion. may require adequate bonding and insurance if the 

bonding and insurance requirements of the recipient are not deemed adequate to protect the 

interest of the Federal Government. 

DTRA may require adequate fidelity bond coverage where the recipient lacks sufficient 

coverage to protect the Federal Government's interest. 

Where bonds are required in the situations described above, the bonds shall be obtained from 

companies holding ce11ificates of authority as acceptable sureties, as prescribed in 31 CFR 

Part 223. ''Surety Companies Doing Business with the United States." 

5. Modification of the Grant. 

The only method by which this Grant may be modified is by a formal, written modification 

signed by the Grants Officer. No other communications. whether oral or in writing, are 

valid. 

Prior Approvals are required as follows: 

1) Expenditures on equipment costing $5,000 or more not specifically identified in the 

budget at time of award. (Approval via written notification from the Grants Officer.) 

2) Expenditures for foreign travel not specifically identified in the budget at time of award. 

(Approval via written notification from the Grants Officer.) 

Page 2 of 18 
Revised 6 April 20 l 8 EXHIBIT B 

3) Prior approval is not required to transfer amounts budgeted for indirect costs to absorb 

increases in direct costs, or vice versa. 

4) Prior approval is not required to carry forward an unobligated balance to a subsequent 

period of performance under this award. 

6. Payments. 

The 2 CFR 200 governs responsibilities concerning payments, with the following 

clarifications: 

Recipients shall submit requests for payment using Invoicing, Receipt, Acceptance, and 

Property Transfer (iRAPT) at https://wawf.eb.mil/. Any request for advance payments must 

be approved by the Administrative Grants Office shown in Block 6 of the award. The 

request shall be submitted to the Administrative Office identified in Block 6 of the Research 

Grant by entering the following routing codes: 

1) Pay Office DoDMC: See Block 12 (Code) on the first page of the Grant. 

2) Invoice Type: Grant and Cooperative Agreement Voucher. 

3) Issue By DoDMC: See Block 5 (Code) on the first page of the Grant. 

4) Adm in DoDMC: See Block 6 (Code) on the first page of the Grant. 

5) Grant Approver: Same as Admin DoDAAC (Leave Ext. blank). 

Payments will be made by the Defense Finance and Accounting Service (DFAS) office 

specified in the Research Grant (Block 12). 

A foreign awardee must have a U.S. bank account and be signed up for electronic payments 

(electronic funds transfers (EFT)). 

7. Funding Increments and/or Options. 

The recipient is advised that the Grantor's obligation to provide funding for increments 

and/or options included in the Grant is contingent upon satisfactory performance in the 

judgment of the DTRA Scientific Officer/Technical Monitor and the availability of funds. 

Other factors will be considered before options will be exercised (for example, expenditure 

rate and current programmatic objectives). Accordingly, no legal liability on the patt of the 

Grantor exists unless or until funds are made available to the Grantor and notice of such 

availability is confirmed in writing to the recipient. Refer to the Funding Profile in Section G 

of the Grant for additional incremental funding planned, but not currently obligated for the 

Grant. 

Funding Increments - In no event is the Government obligated to reimburse the recipient for 

expenditures in excess of the total funds allotted by the Government to this agreement. 

Recipients should note that low expenditure rates reported on payment requests may be cause 

for defe1rnl of future increments. The Government anticipates unilateral modifications for 

funding increments. 

Options- If the agreement contains Option(s), the Government reserves the right to exercise 

the Option(s) unilaterally. 

Page 3 of 18 
Revised 6 April 20 l 8 EXHIBIT B 

8. Patent Rights. 

Patent Rights are governed by 37 CFR 401.14 with the following clarifications: All DTRArelated disclosures. confirmatory licenses to the government, patent applications, and other 

communications should be submitted as detailed herein. 

The 37 CFR Part 401 invention reporting requirements are summarized in the table below. 

Unless otherwise indicated in the "Submission to DTRA '' column, the grantee is required to 

upload the following types of invention information using iEdison (https://sedison.info.nih.~ov/iEdison/), a single web interface for government grantees to report details 

of inventions and patents. If the grantee organization is not already an iEdison registrant. 

then iEdison registration is required prior to submission of the below invention repmts. The 

grant shall not be closed out until all invention repmting requirements are met. 

Page 4 of 18 
Revised 6 April 20 l 8 

Action 

lnnntion Rtpo11: Tht gmntee mu~t 

,ubmit a repnt of an; '\ub_ ect" mw,1ti,,n 

lhneJHl mJ'il identify mrcn\c,n\l. 

kd,:rnl ag.:ncy{i.:s). grant mmbrr(s). and 

date of any pJblic di:y;;\ocrure. Date o:· 

,ulrn1is,1,1n estahl ,hes time frmnes for nil 

full[(' acliom ~IL'il Gt' con-plelt in 

t.:c~n1ca. d.:ta1l. l ho: r,110rt should b~ 

duected to th; kaj agmcy. 

Rightso Inwntion\ on Subtonlmcl\: 

Sulxontrnctm retain riQhts t' their subject 

inl"cntions. ~ • 

F.!ectinn of Til!f to Innntion: Cirnrtee 

mgamzaliPn mu,t notifr thr federal 

agency '>jl0nlOI tfnt it ,1ill retain 

mrnmhip ofinl"cntion am! take step, lo 

cornmm1aliz.: th,: mmtion. 

Confirmato~· licrnse J'h, grantw 

organization must pron de 2 nonmlusm. 

non:mn,feraMe irrmx:ahle paid-up 

limse for th~ gmerrunent ·0 pnctic~ ,1r 

ha1 cthe 1m cntion practiced on ih Gt'half 

thrcughc,ut the wcrld. 

\oneler1ion of Tille fo Imen!ion: 

Gramee :>rga1iration m u:.1 notil\ the 

kd,:ral spomor th.it it will not rdam 

ownership of an m1"cnt1on. 

A1signment of Inmtion Rightso 1hr 

lnuntor The 1mentor may re411'1 

a-;s1gm1ml of in, mtitlfl ng.1h _\gencies 

,upr,ort ri:quc,ts cf thi:1 typ,: to 1·anollily. 

In all cases. cocul'.lentation 1s rqmr(d 

whm atranue orJamzation wa:\'esnghts 

to the ml"enti:in andthr 1m·~ntor(~) wishes 

to rrtain the imention rights. 

Page 5 of 18 

Whrn 

inwntrn\ initial rrnrt to 

the grankconlrnctor 

:irgaruzat:on. 

Sam, repcirtin~ 

respon,ibilitie\ obligatit,ns 

,ml time fram~, a, pnn:e 

grantci: organ1zat1cn. 

l\"ithin ~ years of rcpmting 

the mwntiPn lo the lea( 

feJernl agenc) '>jl01S01 ilf 

JiscbseJ publicly. this 

p,:rwd L> Jm,a,,d.j 

'..'ommm,urat~ with ri:rort 

Jar.y initial ratcn: filing. 

unle,s the m\'cntio1 b 

r>i'ing licewd as a1 

unplltentcd biological 

matmal or w~arch tool. 

l\"ithin ~ wms of rcp,ll1ing 

it' fe,lernl agencr rnns,>r. 

]f d1sclosi:d pubhdy this 

penc,d L~ demased.) 

At t~.e time th.: gra~tee 

.1rgani1~t on elect, n,it to 

rur,ue tit:c mil the 1 inwmor ri:qu~stsr:ghts m 

the mwmion. 

Oiwi!i.\ion 

There 1s no single format for disclosing the

imention totl1e gornnme,1t The 

commLmrnlion ,huulJ mdude the 1i1le ,Jl"thc 

1mo:ntion. dati: o:·anypub:ic d1Sclosuri:. nam.:s 

of all imentm. souro:(~) of federal funding 

(i e grant nLmhcr) n written description of the 

im?nlion intrdmcal ddail Thr in?nlion 

disdo:,11ri: should bo: ~1gn.:d by thi: mi:mon:s,: 

at the Hry lmt s1g11d bya grantee mstitlllional 

official. 

PrUTie gantee 01garumti,1n cannot 1rt1uire 

011nmhip of su1'contllctrn\ ,ubject 

imcntionfs). 

Efoti1eli ~ wa1w tJ the gm crnment ~ier 

further rel"itw th~ federal Bgrnc; -;p:imor may 

i:kct tit Ii: onb.:half of th.: gornnm~nt. Tak 

d(}(s not actually \'est with the Jm·emmmt unul 

gowmmentl eels to ·etarn title. 

Firsl th: grrnt~e orgamzalion must elect noto 

rct.11n right, 1n the imenti,m Sceiml. the 

inwnlt" must w1uesl 1hf a\'.Sll_cU!lt'nt of righh 

agr,.: tc, all tms a-;soc1at(d with 1m·cmion 

rerortir.g asdetaikd m 37 CFR ~11]. andmu11 

pursue conniercrnhzation of the ml"entiun 

thrn1gh patent tiiing or lic,n~ing as awmc1 

t,x,l. Srecifi~ prwdue, b ary agency ,hould 

he Jekm1in~J pnm lo init:aling there41.1c,t. 

J7CFR 

Rrfmnct 

M.14(a)(~) 

4ill.14fc)(l) 

4ill.14!g)(l) 

~ii 1.14({1!~) 

M.l4(h:; 

~ill.14!N1:1 

~ill.14!c)(~) 

~lll.14{(i]) 

~i1l.l4(c)(~) 

~ill.14ftr, 

~111.14(k)(l) 

n,m-jllo~ts 

EXHIBIT B 

Suhmissfon to OTRA 

Submit elcctrnnical y hyuploading 

either a PDF. TIFF. t'r te\t ll.e 

L1rough i~dism. 

fowntit1nfadJ'>lll'- contirmatorr 

l:wre ar,,1 proof of gm ·1 suppoit 

dau>< shall hcsubmiue<l 

,kctromcally til"ough il:d1son. 

Submit elrctrnnical'y through 

irdi'>On 

Submit i:kctromcal.y by uploading 

either a PDf or Tiff fik through 

i~di~on 

Submit elcctronical'y through 

itdi'illn 

Thi~ status sha:l be indicated usm~ 

i~faon. Sul1m-,s1011,if all ,lier 

i»ucs fsm:h a,ouhtanding r,qmwl 

cocum,m,:i should X r.:solHd 

rnor to prxeedmg funher. 

Subm1ss1on of the r.:quued 

documents will he Cone 

electromcall; liy upl0ad11g eithe1 a 

PDF. TIFF. or le.\t rile through 

L:d1,on. 
Revised 6 April 20 l 8 EXHIBIT B 

Action When Discussion J7CFR Submi11Sion to DTRA 

Refmnct 

Initial Patent .-\pplirntion The g1mrtrr \\"ithin 1 rrm 31\er clec'ion Timr frame nmrrnrl' if 1wntit'Jl become, 4ill.14!c)(3) _\ll filing dat3 1h3ll he subnfrtrd --

mu,t mforrn the g:m:rnmcr.t o!'che mmal Jf titk unkss thm 1s an pub he. The tcmi miual patent 3pplirnucn -l111.1n: \'la 1Ed1so1 Endencc ofinC:us101 

paknl application 1ha1 rdatc<l to any c\1en,ion mean, a nonprnl'isional r.s. national t,f gornnmcnt ,up~rl dau,, ,ha.I 

\Ub_iect l1wntion The patrnt application application fr pitent as Mind in _\7 CFR br submittrd elrctrorucalh- a1 eithrr 

mu,t mclud, agornnmm supron claim. !.>( a)(3). l.1, not1fieo11or. m!N mclud, th,: a PUF or ."!fflk through tEd1scn. 

Jlillcnt 3pplirnti,1n nu1:1bcr andti lint date 

ao.•1gncd hy the 1·sPTO .l,copy ot'thr foll 

application 1, nol r,:~urr.:J. 

Assignment to Third Par~·: If m1gnmcn1 ~pprornl. ihirJ rarty mml pur,uc -\II l.1-!1 k) for Documcnl!ilion ,h~ll he ;ubmittcC 

Dnrnmr1tation ncw,~111' whrn a cnmmc-crnlm.twn of the nrn1t10n ·hrncyh Mn-pnrits clrctrnrncalll' a~ r1thcr a PDF or 

grant" oontractor 111sh,:s to astgn pai,:nt f1hng orh~-:ITTmg of th, m\'.:nllor. as a \01,1h, nn flk through !l:d1son. 

mwmion 11ghh tc thud pmty If thr 1Nmth toul Specific pwwlu:r> to 1rq11C>tli-;tincti-:111 

grantee contractor is a non-~ro!'n. tht th~d party aNgnncnt ma\' rnry brnmn bwmn 

go\'~mmcnl mu:;l appr cl\ c l1c a,:ngrL11cnl. ugencic:;. Comull DIR..\ pnorlo ntli~ling sm~ll 

For prnf:t or ,mali bw;:nr,, grnmr rm1r:;t bu,inr»rs 

con,rnctm" du notn-:.:d to :.:,kapμrol"al.f and nonthe '.1ghts mr n»1gncd. nrw ngh1:; hrkkr profit 

as,umcothc ,ams rqxirtmg rs:;ron:;1b1ht1cs organwst1or1>. 

a:; 1hr gr mkc nin\rnclur mganw1l1on 

h1md Pall'lll: 1Jra111tt111,1111\lrnk .\t 11:r lillir \lf 1ssi11 P;iknl 1m1,1 111d1.d1• g,,1•111111r11t ,11p1x11 I cl:nhr 411I ~IIY~) .\ll 1s-t1cd pak:1tn1\1111wli\l11 ,lr,ill 

kdernl agenc1· S[K'nsor With patent i,sut -Ill] I.J((H:{I 1'e prornltd u~·ng 1Ed1,on 

Jak. nwubcr. lillt of ]l<lttnl an~ c1 iJcni;,' bi<lcni;c vf mdua1on ol 

of gownmrnt ouprort d,1uo,:> fOrnnn1ent ,upporl cmioe will ~r 

rnll"lded dectromcslly ;::; al'UJ-or 

TIFF filc thr,,uiliEtliwri 

Request for hlfllsion ofTimr: .\n P1w1 to,1:i; ;tJtUtl 11; bm fateJl',Dll of~ wmo t\11 titlehtil'll aml 01lt' 4ill l.Jl,:U-l1 Rrquc;t elrctirnuca:I; usmg 

rxttITT1on of up to two years may be year for patent apphrnt1on arr prearproml for ll;drnon. 

rc4t1c,1cJ for dcc·.ionf tillc. ,,r on<:) «rr funtlctl m1·cntiom .. .\cltliti,.1ffill cxlcna10m nc,J

for ii ling apc tent applicati11n wrtten apprnYal from the federal agency 

sponsor. 

Di'lfontinuanre of Patent Applirafion, _\tan; tirnr in thr p1o(w, Rrlmrnt mfaun,ction and doc:uwnts fr g4ill 14!1))) !ntlic:ati,1nsh,1L llt' nn1ern 

Pa~mnt of \faintmnct Fm, or but rnor :o e,:abhshrd patrm application or patent) must bi pro1·1drd -liil.6 l;;dmm. 

Defmsr in II Rmuminu!ion or Jea<llinc, sui:h that a <lctcrm1na1ion to pwkct gm clTllll1nt 

Op[Klsilion prncrrding ona Patrnl: mtm.1ts can be nade Tht federal igenc1· 

Grant(( mu:;t noufy kJ.:ral ag.:ncy spoJlS(lr hasth,: cption torurs~ th( pat(nt 

\pt•mor ,ifchangr\ inpatent st:l'.U\ applicati(ln or thr patent if not lrtillf proprrly 

pursu,c or mamtamd .'Illy c!:ang~ m s:atu, 

mL -;t be repuneJ at !cost 3) da) sp11vr tc 

pt'ndmg PTO otlic? a~t1ons 

Page 6 of 18 
Revised 6 April 20 l 8 EXHIBIT B 

Action Whrn Discussion 37CJ/U Submission l UT IL\ 

Refmnu 

Annual Ui!izalion Rrpol1: DTR:\ ,\nmmlly DIR\ requires mention unhzauonreports on 111.l.J(h) Submit drctromcol.y U\tng iEdhon 

n:4uirc, utili1.ation rcp:irting i"or all subject a I~ month reporting ~yck bcg1nnirg in the 

mi-ent10ns that ha-.-e hEd tJtlekctedor me me nth of grantee choosing and contmmr.g 

hcewd without a patent Report mclude, thr:mghout drnt:onof patent Information 

stage of Jmloprncnl. Jatc JJ' first rccurrcmcnl:i M1ncJ m iEJison 

commercial \aleer u-,,:, nunber and !)1'e \"cte: this reponmg requirement. 1f apphcabk 

oflicen.,c.,. g-o,:, ncome. licen.,ing t:i e,1end, heynnd the g:rnnt period 

small busme,s. status of r.s. 

manufoctunngan<l 11lent1firnt10n of my 

FD.'\.-appro1·1J p1:iduct names. 

.-\imual Summa1~· Report ofinnntions: Amrnallr !mention 1e.mrts shall he filed mun.ally jue no ~lll.5(f(3) :;o iEdism subnmomn allowed 

Sum nm me all prmou,ly rrported ~ub,1ecr lwr thin I .'uly of ea:h year 1jmm,effw1w Sullmit Ull Fo@ ~~~- kerort of 

1m·rmi1,nsJ11dcr thi, ~rnnl a1·1,r 11 fanuary ·,l'ill n1,1 rc4u1r: a rcr11r1 umi I Jm·cntinn; ad Suh1rn1rnc1, ·n 

Jul\· tifthe follow mg :--em. --D'J'R:\ Ci ants Offirn. 8725 Jo!m 

.I Kmgm:in 1((1 \IS('6)ll 

Th: rcc1p1cnl :;h,ill us.: D[ For:n SS:. Rqwtof (":7!11B). Fl. Bd1( 1r \"A ::\~Ilm,·ntwn,:wl S.1hwn1rnc1,. lo file· m1\·111or. h~III 

rcr\irl:;_ Ir no 1m ,·n11,i11:; ().;cul r,·J tlu1 lllf the --AJi:1 IRISlrilll\ l ( )Ille,· 1J,·rnillcJ 

:rn1mal 1cr,1r1111g ll<'flcl{I a 11,gallw r:r,in llllll\ n th1• i.Jr:rnt 

he :i!ihn1111,d ••. \:; dir,cicll hy I J 11\ .. cm,111 or 

--1'nrnil h11111 1))882 tu p,11t:1i. 

titr1ha:;:crcsrarcl·.'linnil 1ml !Ille :;111' mu:;t l11· 

b Iha~ 10\ffii fik shuulJ11· namcJ h: the 

Gnnt mrn1bir and ·J11\'el1t1on Re1XJrt" /e.g. 

1 IIJ 111:11.1 :.1.9999 lnHntinn Repru-11 

--The Grnnt ,hall not bi ch,cJ ,iut until all 

1ment1on report11g reqmrenwnts arr mel 

Final Inrrntion Stafrmrnt and Due 11ithe Final lmcnlion rorla ,WIii he likJ al ihc cnJ ofh: ~Ill -i(l\1) \o iFJi,01 auhnmcmn illm1cJ 

Cer1ifiratio11: Re:ioi t all 01..b1ect Iedm1cal Rero1t11tlun '.)ii Gnnt'sPoP !!'no 1ment1:ins occw1e\l dwm~ Subn11t DD Form SS2. Repo1t of 

inwmion., denwd or w1uw1 teprnctice Jay, alier the rrojict mh the life1imr of the awan1 a negatiw report mu,t lnwntion.saml Suhcontrnct~ ·tr 

Jurmg the performarn:e of the grnnt ht ,ubmiu,J. --DTR.-\ Grnnts Onicer. 8725 John 

.. 1:ma1I form DD882 toJ. hmgman RtL \!SC 6).11 

dtnha>"crcscarch:i:nnil mil (f1k ,1,c mu,t !ti' f~27~1B) Ft Bdmr \".-l. 22Y~Iless tillln 1(1\!B). File ,hould Ge named by the (,)1] 

Grant number anJ lnmt1on Report reg. .. _.J.dmrn,;trntiw Olfee 1den11fied 

HDTR. '\.l-12-1-9999 lnHntion R~port). i1th--: Grant 

.. The Grant shall not be cbsed out until all •·.\\ dirwed b)· DTR. \. email or 

imcntion reporti~g requirements arc me1 rortii. 

9. Technical Reporting Requirements. 

Research Performance Progress Report (RPPR). Except under rare cases, RPPRs are 

required annually. The RPPR is due no later than 1 July of each year. Grants effective after 

3 l January will not require a RPPR until l July of the following year. 

The RPPR is not a cumulative report. The first RPPR shall only include actions that 

occurred from the Period of Performance start date up to submission of the first RPPR. Each 

subsequent report shall only include actions that occurred during the 12-month period 

following the previous year's RPPR. 

Page 7 of 18 
Revised 6 April 20 l 8 EXHIBIT B 

A RPPR is not required in the final year of the award if the period of performance ends 

within 60 days of the RPPR due date. In this instance the Final Report will satisfy the 

requirement. Broadly the RPPR shall address the following items: 

• Accomplishments 

• Products 

• Participants and Other Collaborating Organizations 

• Impact 

• Changes/Problems 

Templates and specific instructions will be provided each year in advance of the submission 

deadline. All files must be submitted via email to dtrabasicresearch@mail.mil (individual 

file size must be less than 10MB). A copy of the RPPR should also be provided to the 

Administrative Office identified in the Grant. The file names should be as follows: 

• RPPR: Year Annual Report Grant Number, e.g. 2017 Annual Report HDTRAl-12-1-

9999. 

• Metrics: Year Metrics Grant Number, e.g. 2017 Metrics HDTRA t-12-1-9999. 

Quad Chart. An updated quad chart must be submitted annually. A template will be 

provided each year in advance of the submission deadline. All files must be submitted via 

email to dtrabasicresearch@mail.mil (individual file size must be less than 10MB). The file 

name should be as follows: 

• Quad Chait: Year Quad Chart Grant Number, e.g. 2017 Quad Chart HDTRA 1-12-1-

9999. 

Annual Technical Review. At least one representative (preferably the Pl) for each award is 

expected to attend and present at an annual technical program review meeting, unless 

otherwise exempted by DTRA in writing. For planning purposes reviews will typically be 

for two days in Northern Virginia during the spring or summer months. 

Final Technical Report. A comprehensive final technical report is required: the draft 

document is required forty-five (45) days prior to the end of the Period of Performance and 

the final document is required ninety (90) days after the expiration or termination of the 

award. 

The purpose of the final report is to document and to transition the results of the effort into 

the DTRA and DoD applied research community. The final report will always be sent to the 

Defense Technical Information Center (DTIC) and unclassified reports may be made 

available to the public through the National Technical Infonnation Service (NTIS). 

The final report is more than an extension of previous annual reports. The final report shall 

be a comprehensive technical summary of the significant work accomplished. The final 

report, where it is not readily accessible in published form should, where applicable: 

• Clearly describe and illustrate the experimental equipment, setup, and procedures; 

• Characterize and tabulate collected/computed data in an appendix: 

Page 8 of 18 
Revised 6 April 20 l 8 EXHIBIT B 

• Sufficiently describe computational codes so they can be reproduced. Include a listing of 

the code in an appendix if possible and appropriate: and 

• When the research effort culminates in the production of one or more student theses or 

dissertations, in these cases. the most significant advancements and conclusions 

(equations, figures. relationships. etc.) should be included in an executive summary. The 

theses or dissertations should be attached as appendices only if they are not readily 

available. If they are, dearly reference them and how they can be obtained. Also include 

in the executive summary, cumulative lists of people involved in, and publications 

stemming from. the research effort. Do not include copies of already submitted or 

published aitides in the final report. 

Standard Form (SF) 298, Report Documentation Page. must be used. Item 13 of the SF-298 

should contain a 100 to 200 word abstract summarizing technical progress during the 

reporting period. The SF-298 may be found on the Internet at: 

http:/hN\V\V .gsa.gov/portal/forms/download/116146 

All of the report pages should be prepared for acquisition and distribution by DTIC. All of 

the report pages should be of good quality for copying purposes. No pages should be 

m1ssmg. 

The format and standard required by your institution for the preparation of theses and 

dissertations shall be used for the final report. In the absence of any institutional standards. 

you may wish to refer to the American National Standards Institute (ANSI) document 

239.18-1987, "Scientific and Technical Reports: Organization, Preparation, and 

Production," for guidance. The report may be obtained from: 

American National Standards Institute, Inc. 

1430 Broadway 

New York. NY 10018 

It is anticipated that all final technical reports will be unclassified and that distribution will 

not be limited. However. for final technical reports that require a limited distribution as 

deemed necessary by DTRA, a Distribution List will be provided with the comments on the 

draft final technical report. The Distribution List should be formatted to match the rest of the 

report, placed at the end of the report, and added to the Table of Contents. The number of 

pages in the Distribution List should be added to the total page count and included in the total 

number of pages cited in Block 15 of the SF-298. 

The draft of the final technical report will be due not later than forty-five ( 45) days prior to 

the end of the period of perfonnance. The draft of the final technical report (including a draft 

SF-298) must be submitted electronically as follows: 

• Email the draft of the final technical report to dtrabasicresearch@mail.mil (file size must 

be less than 10MB). The file name should be 'Draft Final Report· and the Grant number, 

e.g. Drat\ Final Report HDTRAl-12-1-9999. 

• Provide a copy of the report to the Administrative Office identified in the Grant. 

Within thirty (30) days, this draft will be reviewed by DTRA and comments will be provided 

to the Grantee to ensure the report complies with DTRA final report requirements. Such 

review and comment does not restrict the conduct or reporting of the project research 

Page 9 of 18 
Revised 6 April 20 l 8 EXHIBIT B 

findings/outcomes and, in accordance with Article 35. does not restrict Grantee's ability to 

publish. Grantee shall incorporate such requested changes so that the report incorporates and 

complies with agreement final reporting requirements terms. Final Technical Reports are 

due ninety (90) days after the expiration or termination of the award. The final submission 

should be made in accordance with the draft final report submission instructions. 

Final Metrics. A final metrics table (in MS Excel format) is required. A template and 

specific instructions will be provided in advance of the submission deadline. The final 

metrics file should be submitted along with the Final Technical Report. The fields contained 

in the final metrics file are analogous to those of the annual submissions. The final metrics 

file shall contain only data from the last annual reporting period until the end of the award's 

funded Period of Performance. 

• Email the final Metrics File to dtrabasicresearch@mail.mil (file size must be less than 

10MB). The file name should be 'Final Metrics' and the Grant number, e.g. Final 

Metrics HDTRAl-12-1-9999. 

10. Financial Reporting Requirements. 

Federal Financial Repmts (SF-425) are due no later than 1 July of each year with data "as of' 

30 May of that year. Grants effective after 31 January will not require a Federal Financial 

Report until l July of the following year. All financial reports shall be submitted to the 

Administration Office identified in Block 6 of the Research Grant. In addition, the Federal 

Financial Report must be submitted electronically as follows: 

• Email the Federal Financial Report to dtrabasicresearch@mail.mil (file size must be less 

than 10MB). The file name should be the Year, 'Federal Financial Report· and the Grant 

number, e.g. 2015 Federal Financial Report HDTRAl-12-1-9999. 

11. Delegation of Administration Duties. 

Certain grant administration duties have been delegated to the Administration Office 

identified in Block 6 of the Research Grant. These duties are as follows: 

1) Provisionally approve all Grant and Cooperative Agreement Vouchers. 

2) Perform all property administration services except the approval of recipient's requests to 

purchase equipment with grant funds. Such approvals must be granted by the DTRA 

Grants Officer. 

3) Perform all plant clearance functions. 

4) Approve requests for Registration for Scientific and Technical Information Services (DD 

Form 1540). 

5) Obtain all financial report(s) (see Article 10 of this document). 

6) Execute administrative closeout procedures, which include the following: 

a. Obtain the final Report of Inventions and Subcontracts (DD Fonn 882). 

b. Obtain final payment request, if any. 

c. Obtain final property report and dispose of purchased property and government 

furnished equipment (GFE) in accordance with the DoDGARs Part 22. Subpart G. 

d. Perfonn a review of final incurred costs and assist the Grants Officer in resolving 

exceptions, if any, resulting from questioned costs. 

e. Assure that all refunds due the Government are received by the Grantor. 

Page l0of18 
Revised 6 April 20 l 8 EXHIBIT B 

NOTE: This term and condition is not applicable to instrumentation and equipment grant 

awards. 

12. Security. 

As a general rule, PI's will not need access to classified security information in the conduct 

of research supported under this Grant. Should it appear that access to such information is 

desirable the recipient shall advise the Grantor and request clearance for the investigator. 

Should information be developed during the course of work under this Grant that, in the 

judgment of the PI or the recipient, should be classified, the Grants Officer shall be notified 

immediately. 

13. Representations and Assurances. 

By accepting funds under this Grant, the recipient assures that it will comply with applicable 

provisions of the national policies and statutory/regulatory/executive-based requirements 

detailed below. 

LIVE ORGANISMS. By signing this agreement or accepting funds under this agreement, 

the recipient assures that it will comply with applicable provisions of the following national 

policies concerning live organisms: 

1) For human subjects: 

a) Adhere to the requirements for protection of human subjects per the DoD level terms 

and conditions as well as the following DTRA requirements: 

b) The recipient shall adhere to DTRA local clause 252.223-9002 - Protection of 

Human Subjects (Aug 2010). The full text of this clause is as follows: 

All research under this grant involving human subjects must be conducted in 

accordance with 32 CFR 219, 10 U.S.C 980, and DoDD 3216.02, as well as other 

applicable federal and state regulations. Grantees must be cognizant of and abide by 

the additional restrictions and limitations imposed on the DoD regarding research 

involving human subjects, specifically as regards vulnerable populations (32 CFR 

219 modifications to subparts B-D of 45 CFR 46), recruitment of military research 

subjects (32 CFR 219), and surrogate consent ( t O U.S.C. 980). 

DTRA Directive 3216.01 of June 9, 2010 establishes the DTRA Human Subjects 

Protection Program. sets forth the policies, defines the applicable terms, and 

delineates the procedures necessary to ensure DTRA compliance with federal and 

DoD regulations and legislation governing human subject research. The regulations 

mandate that all DoD activities, components, and agencies protect the rights and 

welfare of human subjects of study in DoD-supported research, development, test and 

evaluation. and related activities hereafter refeITed to as "research". The requirement 

to comply with the regulations applies to new starts and to continuing research. 

The DTRA directive requires that research using human subjects may not begin or 

continue until the Defense Threat Reduction Agency's Research Oversight Board 

(ROB) has reviewed and approved the proposed protocol. Grantees and 

subcontractors are required to submit a valid federal assurance for their organization 

Page II ofl8 
Revised 6 April 20 l 8 EXHIBIT B 

(institution. laboratory, facility) that has been issued by either DoD or the Department 

of Health and Human Services, and documentation of review of proposed protocols 

by the local Institutional Review Board (IRB) to include consent forms for any 

planned research using human subjects to the DTRA ROB for its review through the 

Grants Officer's representative (if assigned) or the Grants Officer. The ROB review 

is separate from, and in addition to, local IRB review. 

A study is considered to involve human research subjects if: 1) there is interaction 

with the subject (simply talking to the subject qualifies; no needles are required); and 

2) if the study involves collection and/or analysis of personal/private information 

about an individual. or if material used in the study contains links to such 

information. 

Written approval to begin research or subcontract for the use of human subjects under 

the proposed protocol will be provided in writing from the DTRA ROB, through the 

Grants Officer. A copy of this approval shall be maintained by both the Grantee and 

the government. Any proposed modifications or amendments to the approved 

protocol or consent forms must be submitted to the local IRB and the DTRA ROB for 

review and approval. Examples of modifications/ amendments to the protocol 

include but are not limited to: 

• a change of the PI; 

• changes in duration or intensity of exposure to some stimulus or agent; 

• changes in the information requested of volunteers, or changes to the use of 

specimens or data collected; or 

• changes in perceived or measured risks or benefits to volunteers that require 

changes to the study. 

Research pursuant to such modifications or amendments shall not be initiated without 

IRB and ROB approval except when necessary to eliminate apparent and immediate 

hazards to the subject(s). 

Research projects lasting more than one year require IRB review at least annually, or 

more frequently as required by the responsible IRB. ROB review and approval is 

required annually. The Grantee or subcontractor must provide documentation of 

continued IRB review of protocols for ROB review and approval in accordance with 

these Tenns and Conditions. Research must not continue without renewed ROB 

approval unless necessary to eliminate apparent and immediate hazards to the 

subject(s). 

Non-compliance with any provision of this clause may result in withholding of 

payments under the grant pursuant to the grant's payments clause(s) and/or grant 

termination pursuant to the grant's termination clause(s). The government shall not 

be responsible for any costs incurred for research involving human subjects prior to 

protocol approval by the ROB. 

2) For animals: 

a. Adhere to the requirements for protection of animal subjects per the DoD level terms 

and conditions as well as the following DTRA requirements: 

Page l2ofl8 
Revised 6 April 20 l 8 EXHIBIT B 

b. DTRA local clause 252.235-900 t - Prohibition of Use of Laboratory Animals (Jul 

2010). The full text of this clause is as follows: 

The grant recipient shall obtain approval from the US Army Medical Research and 

Material Command (MRMC), Animal Care and Use Review Office (ACURO) prior 

to conducting research on live nonhuman vertebrates. Studies involving non-human 

primates. dogs, cats. or marine mammals will require a site visit by an A CURO 

laboratory animal veterinarian as a condition of approval. DoD may also conduct site 

visits involving research on other animals when deemed appropriate. The animal 

research facility is responsible for notifying the DoD sponsor if Association for the 

Assessment and Accreditation of Laboratory Animal Care accreditation is lost or the 

facility is under USDA inspection. DoD also has the right to a site inspection under 

these circumstances. 

The grant recipient (including subcontractors) is expressly forbidden to use laboratory 

animals in any manner whatsoever without the express written approval of MRMC 

ACURO. 

The grant recipient shall complete the ACURO Animal Use Appendix for Research 

Involving Animals found at the following web site: 

http:/ /mrmc.amedd.arm y. mi 1/i ndex .cfm '?pageid=research protections.acuro ani malap 

pendix. Submit the completed ACURO appendix. contact information, the DTRA 

grant number and a copy of the grant for processing to the email address listed at the 

ACURO website. Once ACURO approves the effort, the grant recipient will receive 

written approval to begin animal use from the US Army MRMC ACURO by separate 

email. The grant recipient shall promptly provide a copy of the approval to the 

Grants Officer and Grants Officer representative. After approval, changes or protocol 

amendments must be submitted to and approved by ACURO before implementation. 

The grant recipient, or subcontractors as appropriate, shall submit the most recent 

U.S. Department of Agriculture Animal Care Inspection Report annually in 

accordance with instructions provided. 

Non-compliance with any provision of this clause may result in termination of the 

grant. 

DoD Instruction 3216.01, dated September 13, 2010, provides policy and 

requirements for the use of animals in DoD-funded research based on Army 

Regulation 40-33. The DoD definition of animal is any live nonhuman vertebrate. 

All proposals that involve the use of animals must be in compliance with DoD 

Instruction 3216.01 and AR 40-33. DTRA requires that research using animals not 

begin or continue until the ACURO has reviewed and approved the proposed animal 

use. For animals. the provisions include rules on animal acquisition, transport. care. 

handling, and use in: (i) 9 CFR parts 1-4, Department of Agriculture rules that 

implement the Laboratory Animal Welfare Action of 1966 (U.S.C. 2131-2156); and 

(ii) the ''Guide for the Care and Use of Laboratory Animals," National Institutes of 

Health Publication No. 86-23 

RESEARCH INVOLVING RECOMBINANT DNA MOLECULES. Any recipient 

performing research involving recombinant DNA molecules and/or organisms and viruses 

Page l3ofl8 
Revised 6 April 20 l 8 EXHIBIT B 

containing recombinant DNA molecules agrees by acceptance of this award to comply with 

the National Institutes of Health "Guidelines for Research Involving Recombinant DNA 

Molecules," July 5, 1994 (59 FR34496) amended August 5, 1994 (59 FR40170) amended 

April 27, 1995 (60 FR 20726), or such later revision of those guidelines as may be published 

in the Federal Register. 

COMBATING TRAFFICKING IN PERSONS. The recipient agrees to comply with the 

trafficking in persons requirement in Section 106(g) of the Trafficking Victims Protection 

Act of 2000 (TVPA). as amended (22 U.S.C. 7104(g)) as implemented by 2 CFR 175. 

1) Provisions applicable to a recipient that is a private entity. 

a. You as the recipient, your employees, sub-recipients under this award, and subrecipients' employees may not-

• Engage in severe forms of trafficking in persons during the period of time that 

the award is in effect; 

• Procure a commercial sex act during the period of time that the award is in 

effect; or 

• Use forced labor in the performance of the award or subawards under the 

award. 

b. We as the Federal awarding agency may unilaterally terminate this award, without 

penalty, if you or a sub-recipient that is a private entity-

• Is determined to have violated a prohibition in paragraph l)a. of this award 

term; or 

• Has an employee who is determined by the agency official authorized to 

tenninate the award to have violated a prohibition in paragraph l)a. of this 

award term through conduct that is eithero Associated with performance under this award; or 

o Imputed to you or the sub-recipient using the standards and due process 

for imputing the conduct of an individual to an organization that are 

provided in 2 CFR Part 180, "OMB Guidelines to Agencies on 

Government-wide Debarment and Suspension (Non-procurement)," as 

implemented by our agency at 2 CFR Part 376. 

2) Provision applicable to a recipient other than a private entity. 

a. We as the Federal awarding agency may unilaterally terminate this award, without 

penalty, if a sub-recipient that is a private entity-

• Is determined to have violated an applicable prohibition in paragraph l)a. of 

this award term; or 

• Has an employee who is determined by the agency official authorized to 

tenninate the award to have violated an applicable prohibition in paragraph 

1 )a. of this award term through conduct that is eitherPage l4ofl8 

o Associated with performance under this award; or 

o Imputed to the sub-recipient using the standards and due process for 

imputing the conduct of an individual to an organization that are provided 

in 2 CFR Part 180, "OMB Guidelines to Agencies on Government-wide 
Revised 6 April 20 l 8 EXHIBIT B 

Debarment and Suspension (Non-procurement)," as implemented by our 

agency at 2 CFR Patt 376. 

3) Provisions applicable to any recipient. 

a. You must inform us immediately of any information you receive from any source 

alleging a violation of a prohibition in paragraph 1 )a. of this award term. 

b. Our right to terminate unilaterally that is described in paragraph l)b. or 2)a. of this 

Article: 

• Implements Section 106(g) of the TVPA, as amended (22 U.S.C. 7104(g)), 

and 

• Is in addition to all other remedies for noncompliance that are available to us 

under this award. 

c. You must include the requirements of paragraph 1 )a. of this award term in any 

subaward you make to a private entity. 

4) Definitions. For purposes of this award term: 

a. "Employee" means either: 

• An individual employed by you or a sub-recipient who is engaged in the 

performance of the project or program under this award; or 

• Another person engaged in the performance of the project or program under 

this award and not compensated by you including, but not limited to, a 

volunteer or individual whose services are contributed by a third party as an 

in-kind contribution toward cost sharing or matching requirements. 

b. "Forced labor" means labor obtained by any of the following methods: the 

recruitment. harboring. transportation. provision. or obtaining of a person for labor or 

services, through the use of force, fraud, or coercion for the purpose of subjection to 

involuntary servitude, peonage, debt bondage, or slavery. 

c. "Private entity": 

• Means any entity other than a State, local government, Indian tribe, or foreign 

public entity, as those terms are defined in 2 CFR 175.25. 

• Includes: 

o A non-profit organization, including any non-profit institution of higher 

education, hospital. or tribal organization other than one included in the 

definition of Indian tribe at 2 CFR t 75.25(b ). 

o A for-profit organization. 

d. "Severe forms of trafficking in persons," "commercial sex act," and "coercion" have 

the meanings given at Section 103 of the TVPA, as amended (22 U.S.C. 7102). 

PROHIBITION ON USING FUNDS UNDER GRANTS AND COOPERATIVE 

AGREEMENTS WITH ENTITIES THAT REQUIRE CERTAIN INTERNAL 

CONFIDENTIALITY AGREEMENTS. The recipient agrees to comply with the 

requirements in section 743 of the Financial Services and General Government 

Appropriations Act, 2015 (Division E of the Consolidated and Further Continuing 

Appropriations Act, 2015, Pub. L. 113-235): 

Page l5ofl8 
Revised 6 April 20 l 8 EXHIBIT B 

1) The recipient may not require its employees, contractors. or sub-recipients seeking to 

report fraud, waste, or abuse to sign or comply with internal confidentiality agreements or 

statements prohibiting or otherwise restricting them from lawfully reporting that waste, 

fraud. or abuse to a designated investigative or law enforcement representative of a 

Federal department or agency authorized to receive such information. 

2) The recipient must notify its employees, contractors, or sub-recipients that the 

prohibitions and restrictions of any internal confidentiality agreements inconsistent with 

paragraph 1) of this award provision are no longer in effect. 

3) The prohibition in paragraph l) of this award provision does not contravene requirements 

applicable to Standard Form 312, Fonn 4414, or any other form issued by a Federal 

department or agency governing the nondisclosure of classified information. 

4) If the Government determines that the recipient is not in compliance with this award 

provision, it: 

a. Will prohibit the recipient's use of funds under this award, in accordance with 

section 743 of Division E of the Consolidated and Fmther Continuing Resolution 

Appropriations Act. 2015, (Pub. L l 13-235) or any successor provision of law; 

and 

b. May pursue other remedies available for the recipient's material failure to comply 

with award terms and conditions. 

14. Data Collection. 

Data collection activities, if any, performed under this Grant are the responsibility of the 

recipient. Awarding agency support of the project does not constitute approval of the survey 

design, questionnaire content, or data collection procedures. The recipient shall not represent 

to respondents that such data are being collected for or in association with the awarding 

agency without the specific written approval of the cognizant awarding agency official. 

However, this requirement is not intended to preclude mention of the awarding agency 

support of the project in response to an inquiry or acknowledgment of such support in any 

publication of this data. 

15. Publications and Acknowledgement of Sponsorship. 

Publication of results of the research project in an appropriate professional journal is 

encouraged as an important method of recording and reporting scientific information. 

The recipient agrees that in the release of information relating to the grant, such release shall 

include the following statement. ''The project or effort depicted was or is sponsored by the 

Department of the Defense, Defense Threat Reduction Agency. The content of the 

information does not necessarily reflect the position or the policy of the federal government, 

and no official endorsement should be inferred." For purposes of this provision, information 

includes news releases. articles. manuscripts. brochures. advertisements, still and motion 

pictures. speeches, trade association proceedings. symposia. etc. 

When issuing statements, press releases, requests for proposals, bid solicitations. and other 

documents describing projects or programs funded in whole or in part with federal money. all 

recipients receiving federal funds, shall dearly state: (i) the percentage of total costs of the 

Page l6ofl8 
Revised 6 April 20 l 8 EXHIBIT B 

program or project which will be financed with federal money, and (ii) the dollar amount of 

federal funds for the project or program. 

16. Authorization to Perform Activities Abroad. 

If the award recipient is a foreign institution. the recipient assures that it has been duly 

authorized to operate and do business in the country or countries in which the grant is to be 

performed; that it has obtained all appropriate licenses, permits. and approvals required in 

connection with the grant's proposed activities; and that it will fully comply with all the laws. 

decrees, labor standards and regulations of such country or countries during the perfonnance 

of the grant. U.S. Government funds may not be used in support ofa project which is 

prohibited by law in the country or countries in which it is undertaken. DTRA does not 

assume responsibility for the recipient's compliance with the laws and regulations of the 

country or countries in which the activities are to be conducted. 

17. Inconsistency between English Version and Translation of Grant. 

The foreign recipient shall ensure that all contract coJTespondence that is addressed to the 

U.S. Government is submitted in English or with an English translation. In the event of 

inconsistency between the terms of the grant and any translation thereof into another 

language. the meaning in the English language shall control. 

18. Value Added Tax (VAT) and Other Taxes. 

Prior to grant proposal submission, the recipient will require any supplier of goods or services 

using grant funds to consult with it. so as to avoid the imposition of such charges with respect 

to the goods and/or services in question, where possible. As regards to excise duties and other 

taxes imposed on the sale of goods or services (e.g. VAT), the recipient will require any 

supplier of goods or services using grant funds to verify in consultation with the recipient 

whether in the country where the VAT would be payable, if the recipient is exempt from such 

VAT or other taxes at the source, or entitled to claim reimbursement thereof. If the recipient 

is exempt from VAT or other taxes or entitled to claim reimbursement thereof, the recipient 

shall not include costs for VAT or other taxes in the grant proposal. However, the recipient 

may include costs in their proposal to pay for VAT costs associated with travel. including and 

limited to lodging, meals, and transportation. In the event that the recipient is not exempt 

from VAT or other taxes and is unable to claim reimbursement thereof, the recipient must 

itemize VAT and/or other taxes in the grant proposal. Prior to grant award, DTRA and the 

recipient shall mutually agree upon the use of DTRA funds for VAT or other taxes or if 

needed, revise project activities accordingly. 

During implementation of grant activities. the recipient will notify DTRA as soon as they 

become aware of any VAT or othertaxes, exceeding $500.00 per transaction, not identified in 

the grant proposal and outside those considered VAT costs associated with travel, including 

and limited to lodging. meals. and transportation. A ''transaction" is defined as a single 

purchase by the recipient and transactions may not be deliberately split in order to avoid 

compliance with the $500.00 limit. DTRA approval in writing with documentation of 

extraordinary circumstances is required prior to the recipient using any DTRA funds for VAT 

Page l7ofl8 
Revised 6 April 20 l 8 EXHIBIT B 

or other taxes exceeding $500.00 per transaction. and a grant modification may be required. 

The recipient understands that in the event that DTRA is unable to secure approval to use 

DTRA funds for VAT or other taxes exceeding $500.00 per transaction, the purchase of 

applicable items may not proceed. If DTRA and the recipient mutually agree to use DTRA 

funds to pay VAT or other taxes on any item(s) exceeding $500.00 per transaction. the 

recipient will include this infonnation in its financial reports to DTRA. 

Page l8ofl8 
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From: 

To: 

ec, 

Subject: 

Date: 

Attachments: 

Amanda Andre 

b)(6) 

W1ll1 m B. Kr R 

b)(6) 

e: on- o urce e: 

Monday, July 8, 2019 3:01:07 PM 

EHA RVF2 Budget Final.xlsx 

Al k I hm r • (b)(6) 

All active links contained in this email were disabled. Please verify the identity of the sender, and confirm the 

authenticity of all linh contained within the message prior to copying and pasting the addre~s to a Web brow~er. 

Dear all, 

Dr. Kare~h asked me to send the attached budget. 

Best 

Amanda Andre, LMSW 

Program Coordinator 

EcoHealth Alliance 

460 West 34th Street - 17th floor 

New York. NY 10001 

1.212.380.4470 (direct) 

1.212.380.4465 (fax) 

(' a ut ion -www. ecohea 1th al I iance.org 

EcoHealth Alliance leads cutting-edge scientific research into the critical connections between human and wildlife 

health and delicate ecosystem~. \Vith this science, we develop solutions that prevent pandemics and promote 

conservation. 

On Mon, Jul 8, 2019 at 2:49 PM Robinson, Adrea A CTR (USA) fb)(B) 

Caution b)(6) wrote: L------------~ 

Thank you for responding so quickly. Please send what you ha\'c, because we (Contracts) actually look at more 

detail than what was required for the grants.go\'< Caution-http://grants.gtn > submission. 

Thank you, 

From: William B. Karesh <karesh((l\ecohealthalliance.org < Caution-mailto:kareshr1_1'ecohealthalliance.oq,; > > 

Sent: Monday, July 8, 2019 2:46 PM 
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I 

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BK 11815 11815 

CM 14216 7988 

Int Conf travel 4900 

Dom Conf travel 1260 4120 

Meet Assaf 550 550 

Total 41028 43889 

loom Total $1,810 $4,670 

lntn'I Total $39,218 $39,219 

I Total $41,028 $43,889 

39033 

38175 

Y3 Y4 

12416 

11815 

16124 

4900 

4120 

550 

49925 

$4,670 

$45,255 

$49,925 

45191 

vs 

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11815 12501 

7245 4844 

4900 4900 

4120 

550 

43682 

$4,670 

$39,012 

$43,682 

38419 

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$35,797 

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35654 

1260 

To (b)(6) 

Caution~---------------------------" 

Cc: Dr. Melinda Ro~tal <rostal(~;ecohealthalliance.org < Caution mailto:rostaVa'ecohealthalliance. 0 > >· 

Aleksei Chmura <chmura(~;ecohealthalliance.org < Caution mailto:chmurara,ecohealthalliance.oro > >Jbl(B) 

(b)(6) 

Caution-mail!d'b)(B) F >; Amanda Andre <amanda.andre«_-i;ecohealthalliance.org < 

Caution-mailto:amanna.annre a'econea t ia11iance.oro > > 

Subject: [Non-DoD Source] Re: FRBAA14-6-2-0333 

All active links contained in this email were disabled. Please verify the identity of the sender, and confirm the 

authenticity of all linh contained within the message prior to copying and pasting the addre~~ to a Web brow~er. 

Dear [b)(B) 

~----~ 

We have a budget for the project in Excel format. but it contains more itemi7ed details than that required for 

~ubmission into the proposal submission system - i.e. multiple rows in our version have to be combined to result in 

the total~ for some of the fields we entered into grant~.gov < Caution http:i/:.irantS.f;JO\' >< CautionCaution-http: 'i:.irantS.f;JOV < Caution-http:/..-f;)rants.:.iov > >. 

We can send you the version we have, but do understand that the rows will not all match one-to-one with the 

~ubmission format. 

Please let me know how you would like us to proceed. 

William 8. Karesh, D.V.M 

Executive Vice President for Health and Policy 

EcoHealth Alliance 

460 West 34th Street - 17th Floor 

New York, NY HlOOl USA 

I 
+ 1.212.380.4463 ( direct) 

+ 1.212.380.4465 (fax) 

Caution-Caution-WW\\'.ecohealthalliance.org < Caution-http:/. ('aution-('aution-www .ecohealthalliance.01·~ > < 

(' a ut ion -(' aut ion -mai Ito: kareslv deco heal tha 11 i ance .o 1·0 < (' aution -mai Ito: kares lv deco heal tha 11 i ance .o 1·0 > > 

President. OIE Working C.iroup on \Vildlife 

Co-chair, IUCN Species Survival Commission - Wildlife Health Specialist Group 

EPT Partners Liaison, USAID Emerging Pandemic Threat~ - PREDICT-2 Program 

EcoHealth Alliance leads cutting-edge research into the critical connections between human and wildlife health 

and delicate ecosy~tems. With this science we develop solution~ that promote conservation and prevent pandemics. 

(b)(6) On Jul 8.2019, at 2: 16 P CautionCaution-(b)(B) 

('autionmailttb~)tF(6ii") ___________ l-cc"c1⁄2cTc 0

c

1

c"~-------------~ 

Good Afternoon. 

Please provide DTRA with a copy of your budget/co~! propo~al in MS Excel. Please ensure all project 

year~ are included and all formula~ are visible. 

Thank you, 
rb)(B) f 'ontractor 

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Reducing the Threat of Rift Valley Fever through Ecology, Epidemiology and Socio-Economics 

PI: William B. Karesh 

Thrust Area 6 - Cooperative Counter Weapons of Mass Destruction Research with Global 

Partners FRCWMD 

Statement ,~f Work 

Project Title: Reducing the Threat ofR(ft Valley Fever through Ecology, Epidemiology and 

Socio-Economics 

Document Date: December 5, 2018 

O~jective: The objective of this grant is to reduce the threat ofRVF by improving the 

understanding ofRVFV circulation during inter-epidemic periods, improving local capacity to 

predict periods of high risk for RVF outbreaks and determining the multi-sectoral cost ofRVF in 

the Republic of South Africa (RSA). Studies in the Free State/Northern Cape (FS/NC) and 

KwaZulu-Natal (KZN) regions will generate new understanding ofRVF maintenance, 

circulation and impacts and improve risk prediction models for the country. Through multidisciplinary investigation of three core hypotheses, the project shall strengthen South Africa's 

leadership role within the African continent to reduce the threat of RVF and other vector-borne 

diseases through the characterization ofRVFV epidemiology and ecology in tropical and 

temperate ecosystems. 

Scope: The grantee proposes a five-year multi-disciplinary study of epidemiology, ecology and 

socio-economic factors in RSA. The grantee team shall focus on the following major goals and 

milestones: 

1. Characterize changes in RVFV activity in mosquitoes and sheep as the length of the 

inter-epidemic period increases (Y 1-OY2). 

• Implement sheep cohort (FS ), vector sampling (FS & KZN) and the collection of 

remote-sensing data; develop and implement new aspects of vector field studies (Y 1 & 

Y3); create an Aedes pan distribution map (Y2). 

2. Determine seroprevalence and characterize the risk factors associated \Vith RVFV 

exposure in humans and domestic ruminants in KZN (Y 1 ). 

• Modify research materials for the isiZulu speaking population; adapt the approach and 

implement a One Health cross-sectional study; conduct risk factor analysis. 

3. Identify the socioeconomic impact ofRVFV in regions where RVFV is present with and 

without a history ofRVFV outbreaks (Yl-Y3; OY4). 

• Establish study protocols, identify economic variables and assess the economic impact 

ofRVFV in FS/NC, KZN (Yl-3) and nationally (OY4), produce a report for policy 

makers. 

4. Develop and implement a sustainable early \Varning system for RVFV in RSA. 

• Collate data collected previously and this study (Yl-3); launch prediction system on 

ARC website (Y3); maintain/test the prediction system (OYI-2). 

5. Improving knO\vledge and capacity (Yl-OY2) 

• Maintain and develop new collaborations \Vith stakeholders; transfer technology for 

additional diagnostic capacity at OVR; provide policy recommendations based on 

socio-economic analysis, training of local technical personnel; training of graduate 

students and post-doctoral fellO\v; publishing and sharing of project findings; host 

entomological and One Health economics workshops and annual Partners and 

Stakeholders Meetings. 

1 
Reducing the Threat of Rift Valley Fever through Ecology, Epidemiology and Socio-Economics 

PI: William B. Karesh 

Thrust Area 6 - Cooperative Counter Weapons of Mass Destruction Research with Global 

Partners FRCWMD 

Background: Rift Valley fever virus (RVFV) is a mosquito-borne virus of public and animal 

health significance. The WHO recently listed RVFV as an R&D Blueprint priority disease, 

noting that fundamental research is needed on the epidemiology and entomology of RVF, 

including multidisciplinary studies. RVFV ecology is complex and poorly understood, 

involving ruminant hosts, human behavior, and mosquito vectors \Vith associated climatic and 

environmental factors. These gaps in knowledge hinder determination of risk ofRVF. RVF 

outbreaks are devastating to farmers, resulting in abortion in nearly 100% of pregnant 

ruminants and high mortality rates among young ruminants (up to 90%). RVFV causes 

influenza-like symptoms and occasional retinitis in people, \Vith a small percentage developing 

severe complications, such as, hepatitis, hemorrhagic fever and encephalitis, which may result in 

death. RVF outbreaks also have significant socio-economic impacts and are interspersed with 

apparent quiescent periods (no reported clinical RVF cases). Multiple species of mosquito 

vectors are responsible for transmitting RVFV to animals. Floodwater Aedes spp. are 

hypothesized to transmit the virus transovarially and their desiccation-resistant eggs can lie 

dormant for unquantified periods of time. Newly emerged, infected Aedes adults can initiate 

epizootics when conditions are suitable. Susceptible Culex spp. can subsequently amplify the 

outbreak. Given the high spatial resolution required to characterize flooded areas (pans), pan 

density and other characteristics have frequently been left out of most spatio-temporal models. 

The evidence for cryptic RVF transmission among livestock in some areas is clear, yet the 

underlying mechanisms are poorly understood. 

Preliminary Data: This project builds on the five-year BTRP-funded "Understanding Rift Valley 

Fever in the Republic of South Africa" Project (URVFRSAP), \Vhich was focused on identifying 

a variety of ecological factors associated with the abundance and succession of Aedes and Cu/ex 

mosquitoes, as well as patterns of immunity in ruminant and human hosts in a region where 

multiple, large outbreaks ofRVF are known to have occurred in the Free State and Northern 

Cape Provinces. Despite the magnitude of these outbreaks (producers lost an estimated US$26. l 

million in 2010-11) we found livestock to be highly susceptible ( estimated at only 30% 

seroprevalence of antibodies against RVF). During the inter-epidemic period, we identified an 

incidence rate of 3.2% seroconversions per sheep-year. We associated several soil and vegetation 

factors with previous RVF livestock cases that will provide a foundation for improved RVF 

predictions. Preliminary findings from project partners suggest RVFV may be endemic in parts 

of KwaZulu-Natal (KZN), where clinical RVF has not been reported but where the 

seroconversion rate is extremely high (54% per animal-year; Van den Bergh, In Prep). We 

developed a strong relationship \Vith stakeholders in South Africa, \Vith 54 participants from 26 

public and private institutions attending our recent Stakeholders and Partners Meeting in 

Pretoria. We strengthened our relationship with the Department of Agriculture, Forestry and 

Fisheries, by presenting regular updates and incorporating their feedback into our project. 

Applying a rigorous One Health investigation, the URVFRSAP has generated critical 

knowledge, capacity and a strong stakeholder base for South Africa to serve as a regional leader 

in the threat reduction of RVF. 

Key references include (further references can be found in the Project Narrative): 

Anyamba A, et al. 2010 Prediction, assessment of the Ril1. Valley fever activity in cast and southern Africa 2006-

2008 and possible vector control strntcgics. Am J Trop \1cd Ilyg. 83(2):43-51. 

2 
Reducing the Threat of Rift Valley Fever through Ecology, Epidemiology and Socio-Economics 

PI: William B. Karesh 

Thrust Area 6 - Cooperative Counter Weapons of Mass Destruction Research with Global 

Partners FRCWMO 

Linthicum, K. J., et al. 1984 Mosquito species encountered in a Hooded grassland dambo in Kenya. \1osq News 

44: 228-232. 

\1dlulwa, Z. & Klein, K. 2015 Socio-economic impacts of lumpy skin disease and Rift Valley fever on the South 

African livestock economy. (ARC-LNR Report). 

Williams, R., et al. Anomalous high rainfall and soil saturation as combined risk indicator of Rill Valley fever 

outbreaks, South Africa, 2008-2011. Emerg Infect Dis 22 (2016). 

Tasks/Scientific Goals: (Format: Year #(s).Task #. Sub-task#) 

Task Yl.1-Y02.1: Characterizing ecological factors affecting RVFV and RVFV vectors. 

To improve understanding ofRVFV risk in relation to climate and remote sensing indicators, 

vector distribution and RVFV circulation in mosquitoes, and mosquito egg survival to elucidate 

the role of ecological determinants, the grantee shall monitor rainfall (verified by on-site weather 

stations installed during the URVFRSAP), temperature, and vegetation conditions. The grantee 

shall utilize geospatial information sources (including long-term (2000-2017) high-resolution 

scenes covering areas where the 2008 to 2011 outbreaks occurred, Landsat data, ARC Land Type 

maps, and historical outbreak maps) to assess changes over time that may be correlated with 

RVF risk, including Aedes abundance. To monitor vector dynamics, the grantee shall select 

approximately 5 sites (pans) from among previous URVFRSAP sites for \Veekly longitudinal 

mosquito sampling in the FS/NC study region during the wet season (and at intervals during the 

dry season/winter). The awardee shall select 1-3 sites in KZN for monthly sampling to improve 

our understanding of the vector dynamics in this region. The grantee shall conduct quantitative 

real time RT-PCR for RVFV on pooled mosquito samples (by species) at NICO. The mvardee 

shall analyze bioecological and ecological factors, produce an Aedes pan distribution map and 

develop a real-time RVF outbreak prediction system monitoring RSA. To understand survival, 

Aedes eggs shall be collected and maintained in controlled conditions for varying periods of 

time. After varying time periods, eggs shall be stimulated to hatch in a containment facility at the 

NICO before being collected for species identification and PCR-testing. 

Y 1.1.1-0Y2.1.1 Collection of climatic data to identify different patterns associated with 

Aedes abundance. 

Y 1.1.2-0Y2.1.2 Assess the abundance and diversity of mosquitoes, conduct egg 

desiccation trials. 

Y2.1.3 Develop Aedes pan distribution map. 

Y3.1.4 Complete research synthesis report across project tasks. 

Y3.1.5 Mosquito mark-recapture study on the ecology of flood\vater Aedes. 

Y3.1.6 Develop an early warning system for RVF in the Republic of South Africa. 

OY2.1. 7 Complete analysis of all mosquito data. 

Task Yl.2-Y02.2: Improve the capacity for South Africa to be a regional leader in vectorborne diseases and Rift Valley fever virus epidemiology. 

Strengthening scientific capacity is a key pathway for promoting sustainability of hypothesisdriven research for RVF threat reduction. The grantee shall mentor four graduate students in 

project-related subjects, including epidemiology, public health, entomology, soil sciences, or 

laboratory sciences at local universities. The awardee shall support a post-doctoral fellow 

(named in key personnel) who is interested in becoming an expert in medical entomology and 

\Vill split his time between UP and NICO and contribute to sample collection, identification, and 

analysis. The project shall facilitate technology transfer of inhibition ELISA to OVR to expand 

3 
Reducing the Threat of Rift Valley Fever through Ecology, Epidemiology and Socio-Economics 

PI: William B. Karesh 

Thrust Area 6 - Cooperative Counter Weapons of Mass Destruction Research with Global 

Partners FRCWMD 

laboratory capacity for the detection ofRVFV exposure in animals and concurrently supporting 

operational capacity of the RSA National One Health Forum. To provide capacity strengthening 

and development in vector-borne disease and RVFV epidemiology to aide in threat reduction, the 

grantee shall organize three workshops with participants from southern/South Africa, including 

one on entomology (YI) and two on One Health economics (Y3 and OY2). 

Y 1.2.1-OY2.2.1 Train a minimum of four graduate students in fields related to RVF. 

Yl.2.2-OY2.2.2 Train post-doctoral fellow in medical entomology. 

Y 1.2.3 Conduct entomology \Vorkshop for participants from southern Africa. 

Y2.2.4 Technology transfer of inhibition ELISA to OVR. 

Y3.2.5 & OY2.2.5 Conduct One Health economics workshop for participants from 

southern Africa. 

Task Yl.3-0Y2.3: Identify patterns ofRVFV exposure in ruminants in the absence ofan 

RVF outbreak. 

The project shall monitor RVFV exposure in ruminants to infom1 understanding ofinterepidemic circulation in sheep populations. Despite an absence of reported cases in areas ofKZN, 

preliminary findings from project partners have indicated that RVF may be endemic in some of 

these areas within the province. The grantee shall conduct a cross-sectional study of domestic 

ruminants from up to 158 households in the KZN study area to determine RVFV seroprevalence. 

Under a One Health approach, households \Vill be enrolled (Task 5) in the cross-sectional study 

to analyze epidemiology factors and human and animal seroprevalence levels. To improve the 

knowledge of antibody waning and changes in seroconversion rates, cohort sheep from the 

URVFRSAP in the FS/NC study area shall be re-enrolled to complete a longitudinal study over 

the useful lifespan of a sheep (8 years total). Serological testing of cross-sectional and cohort 

animal blood samples will be conducted using inhibition ELISA and may be confinned with IgM 

ELISA or virus neutralization testing. 

Y 1.3.1 Local permissions are obtained. 

Yl.3.2 Conduct cross-sectional study in KZN. 

Yl.3.3-OY2.3.3 Implement sheep cohort in FS. 

Yl.3.4-OY2.3.4 Conduct serological testing on all cohort and/or cross-sectional animal 

blood samples. 

Y3.3.5 Complete research synthesis report across project tasks. 

OY2.3.6 Complete analysis of ruminant cohort data. 

Task Yl.4-0Y2.4: Identify the socioeconomic impact of RVF within the study areas and 

nationally. 

The awardee team believes that socio-economic determinants of RVF risk are important to 

understand in tandem \Vith epidemiological and ecological factors to infom1 successful threat 

reduction. Prior studies by project partners have estimated substantial agricultural production 

losses to farmers in the FS and NC during the 2010-2011 outbreak; however, wider impacts of 

RVF, including those that may be occurring but not reported in inter-epidemic periods and those 

to a wider range of agricultural and non-agricultural sectors, have not been accounted for to date. 

The grantee shall use a One Health approach to more comprehensively investigate micro-and 

macro-socio-economic impacts ofRVF across multiple sectors. The grantee shall collect socioeconomic, spending, and loss data at household/fann level to estimate micro-socio-economic 

impact in KZN (conducted concurrently \Vith the cross-sectional studies in described in Tasks 3 

4 
Reducing the Threat of Rift Valley Fever through Ecology, Epidemiology and Socio-Economics 

PI: William B. Karesh 

Thrust Area 6 - Cooperative Counter Weapons of Mass Destruction Research with Global 

Partners FRCWMD 

and 5). The grantee shall collect the same socio-economic data from households/farms in the 

FS/NC study area in Year 3. The grantee shall also conduct a study of national-level impacts, 

targeted to government and industry to identify multi-sectoral implications ofRVF risk (OYl). 

Economic data \Vill be paired with epidemiological data to inform prevention and control 

scenarios and compare cost-effectiveness. Workshops shall be held in Y3 and OY2 to strengthen 

regional capacity for economic analysis using a One Health approach, with a focus on policymaking for threat reduction of RVF and other zoonotic diseases. Holding two workshops should 

allow for multi-sectoral involvement and framing of the workshop exercises around timely 

stakeholder-informed policy questions and topics. 

Y 1.4.1 Obtain local permissions to conduct surveys. 

Yl.4.2 & Y3.4.2 Conduct survey oflivestock farmers to estimate spending and losses 

related to RVF. 

Y3.4.3 Complete research synthesis report across project tasks. 

OYl.4.4 Conduct survey of public and private institutions at provincial and national level 

to estimate spending and losses related to RVF. 

OY 1.4.5 Determine sectoral costs and benefits and develop associated policy 

recommendations. 

OY2.4.6 Complete final report for policy makers. 

Task Yl.5-0Y2.5: Compare RVFV exposure in people in areas with different patterns of 

clinical RVF. 

The grantee shall conduct a cross-sectional study of humans (and animals, see Task 3) in the 

KZN region to compare RVFV exposure patterns with the FS/NC region. The awardee shall 

characterize the risk ofRVFV infection to people by initiating a household level cross-sectional 

study (a questionnaire and blood sampling). The grantee shall translate the previously written 

(URVFRSAP) vector-borne and zoonotic diseases booklet into isiZulu for distribution in KZN. 

Laboratory testing of the samples \Vill be conducted at NICO and may include the following 

tests: total antibody ([gG/lgM) RVF ELISAs, inhibition ELISA, lgG specific RVF ELISAs, lgM 

specific RVF ELISAs, and RVFV neutralization test. 

Y 1.5.1 Modify and translate written questionnaire for risk analyses of RVFV infection and 

the written information booklet on RVF and other vector-borne diseases. 

Yl.5.2 Serosurvey mvareness to the community. 

Yl.5.3 Conduct written questionnaire in conjunction with blood collection. 

Yl.5.4 Collect blood samples from participants in the household cross-sectional study. 

Yl.5.5 & Y2.5.5 Conduct serological analyses for human anti-RVFV lgG and lgM. 

Y2.5.6 Complete report of results. 

Y3.5.7 Complete research synthesis report across project tasks. 

Task Yl.6-0Y2.6: Disseminate reports to relevant stakeholders. 

The grantee shall synthesize all data collected through the projects described above as well as 

capacity building activities in South Africa. An annual report shall be developed and 

disseminated to local stakeholders. A database for the extensive amount of data shall be 

developed and used for epidemiological analyses. The project shall submit annual sample 

repository information using a DTRA-specified fonnat. Access to all samples collected and data 

generated during the course of the project, up to and including at least 12 months after the project 

end date. Scientific and general reports shall be generated and findings shall be presented as 

5 
Reducing the Threat of Rift Valley Fever through Ecology, Epidemiology and Socio-Economics 

PI: William B. Karesh 

Thrust Area 6 - Cooperative Counter Weapons of Mass Destruction Research with Global 

Partners FRCWMD 

specified in the grant schedule. A stakeholder meeting shall be held annually to describe the 

project and the current results. Community feedback meetings shall be held to provide aggregate 

findings and engage with local stakeholders through the project. These dissemination pathways 

shall provide opportunities to gain stakeholder input, including to inform policy questions and 

considerations to optimize recommendations for threat reduction to be generated by the socioeconomic study. 

Y l .6. l-OY2.6.1 Submit reports, including sample repository data, to DTRA. 

Yl.6.2-0Y2.6.2 Complete annual report to local stakeholders. 

Yl.6.3-0Y2.6.3 Host annual stakeholders meeting. 

Yl.6.4-0Y2.6.4 Conduct presentations/meetings at times and places specified in the grant 

schedule (Yl Task 6), including DTRA Annual Technical Review. 

Yl.6.5-0Y2.6.5 Submit publications. 

PerjOrmance Schedule: 

To,k 2 Impro,o the capoc,ty for South Afnca to bo a reg,oool loader rn , «tor-born• 

diseases •IWI RJlt Valley fever virus cpldcmiolo~y. 

!-4 Conduct ,cruloe,cal t,·1trn, on all coho It and,orcruss-1cco10nal anmu,l blood ,am kl 

.\.6 ( ·om lek anal '"' ofrum,nant ,·oho rt data. 

4.l<J,t,oinloool • ....,,.to<lOllducl ,. 4.2 Conduct ,urvc oflm:stoek farmers 10 estimate , end in and losses related to RVF. 

4.J Com lete research s nthesis r ort across ro ect tasks, 

4.4 Conduct >llr\'CY of publte and pnvale L11>tlll1tio11, al provrncial and nation al level to 

e>"m"le > cn<lrn • an<I losses n:la<cd lo R\'F, 

Task 1,). rncludrn • DTRA A11nual Technical Rcv,c" 

6 5 Submlt ,ubliccHton, 

6