Test Material: IN-J0290 (transformation product of nicosulfuron) 

MRID 49169701 

Title: Aikens, P.J. 2001. Adsorption/Desorption of [14C]IN-J0290 in Five Soils.

EPA PC Code: 129008 (for parent compound) 

OCSPP Guideline: 835.1230 

For CDM Smith 

 

Primary Reviewer: Kindra Bozicevich Signature: 

 Date: 9/2/14 

Secondary Reviewer: Joan Harlin Signature: 

Date: 9/2/14 

 

QC/QA Manager: Joan Gaidos Signature: 

Date: 9/2/14 
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

2 of 31 

Adsorption and desorption of IN-J0290, transformation product of nicosulfuron, in five 

soils. 

Report: MRID 49169701. Aikens, P.J. 2001. Adsorption/Desorption of [14C]INJ0290 in Five Soils. Unpublished study performed by Huntingdon Life 

Sciences Ltd., Cambridgeshire, England; sponsored and submitted by E.I. du 

Pont de Nemours and Company, Wilmington, Delaware. DuPont Project ID 

DuPont-5264. Huntingdon Project ID DPT 564. Experimental initiation 

February 23, 2001 and completion May 25, 2001 (p. 11). Study completion 

date November 2, 2001. 

Document No.: MRID 49169701 

Guideline: OCSPP 835.1230 

Statements: The study was conducted in accordance with USEPA Title 40 CFR Part 160, 

UK GLP regulations, EC Commission Directive 1999/11/EC, and OECD 

Principles of GLP (p. 3). Signed and dated Data Confidentiality, GLP, 

Quality Assurance, and Certification of Authenticity statements were 

provided (pp. 2-5). 

Classification: This study is Acceptable. The study was conducted using a transformation 

product rather than the parent compound. The study was conducted using 

only three types of soil (loamy sand, silt loam, and sandy loam). Mass 

balances were determined for soils treated at the highest test concentration, 

rather across all test concentrations. 

PC Code: 129008 (for parent compound) 

Reviewer: 

 Gabriel Rothman Signature:

Environmental Scientist Date: August 20, 2015

Executive Summary 

In a batch equilibrium study, four foreign soils (pH range 5.2-7.8) and one U.S. soil (pH 5.5) 

were used to measure sorption coefficients of [pyrimidine-2-14C]IN-J0290 in darkness at ca. 20-

22C. Adsorption phase was conducted using five test concentrations, and the desorption phase 

was conducted using only the highest test concentration. Determined Freundlich Adsorption 

Coefficient (KF) values, ranged from 0.86 to 45.21 L/kg (mean KF = 10.39 L/kg); respective 

KFOC values ranged from 59 to 1458 L/kg (mean KFOC = 458 L/kg).1 Freundlich Desorption 

Coefficients (KF-des) (range 0.002 to 680.6 L/kg, mean KF = 137.9 L/kg) were higher than those 

obtained for the initial sorption measurement, indicating a degree of irreversible sorption. 

Percent adsorption was not reported. Percent desorption, as percent of the adsorbed, ranged from 

21 to 47% of the applied for all test soils. Freundlich exponents corresponding to KF values 

 

1 Sorption is a generic term that applies to absorption, adsorption, and desorption processes. Adsorption refers to 

sorption onto a two-dimensional surface; absorption refers to sorption into a three dimensional matrix. Both types of 

sorption occur in soils and sediments. Desorption refers to a sorbate becoming desorbed from a sorbent. Desorption 

distribution coefficients are measured by removing solution from a sorption experiment and adding fresh solution, 

so that all material measured in solution will be the desorbed material. The guideline uses the term adsorption in 

place of sorption and refers to the initial measurement of sorption.
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

3 of 31 

ranged from 0.71 to 0.86 across all test soils following the adsorption phase and from -2.34 to 

2.86 following the second desorption step. 

Table 3 summarizes the adsorption coefficients measured in the study. Table 4 summarizes the 

desorption coefficients measured in the study. 

Overall recovery was determined only for soils that were treated at the highest test concentration. 

Recoveries ranged from 97.0 to 100.6% of the applied for all test soils. 

Coefficients of variation (CV) were 1.9 to 1.3 across all [14C]-treated soils for adsorption KF and 

KFoc, respectively, and 2.2 and 2.2 across all [14C]-treated soils for desorption KF and KFoc, 

respectively. 

Results Synopsis: 
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

4 of 31 

Table 1. Summary of Adsorption/Desorption Results

A

Soil/ Sediment, % OC pH 

Regressed Kd

(L/kg-soil) Range of 

Kd (L/kgsoil) 

Regressed 

KOC (L/kgOC) 

KF 

((L/kg-soil)-1/n)

1/n for 

adsorption 

(

Value ± 

SE r2 p-value Value ± SE Value ± SE r2 p-value Value ± SE 

Adsorption 

Speyer 2.2 Loamy sand (2.1% OC, pH 6.4) 

1.4 ± 

0.0 0.996 4.77E-12 1.32-2.71 66 ± 1 1.2 ± 1.0 0.998 0.001 0.86 ± 0.0 

Pavia Loamy sand (0.5% OC, pH 5.2) 

2.8 ± 

0.1 0.996 4.3E-12 2.70-7.00 560 ± 12 2.3 ± 1.0 0.998 1.6E-07 0.81 ± 0.0 

Drummer Silt loam (3.1% OC, pH 5.5) 

69.8 ± 

3.8 0.974 1.8E-08 63.78- 391.25 2251 ± 122 45.2 ± 1.1 0.993 4.8E-10 0.71 ± 0.0 

Nambsheim Sandy loam (0.7% OC, pH 7.8) 

0.9 ± 

0.0 0.986 1.1E-09 0.89-2.61 135 ± 5 0.86 ± 1.0 0.998 0.007 0.79 ± 0.0 

Vercelli Silt loam (1.2% OC, pH 5.8) 

3.0 ± 

0.0 0.997 5.4E-13 2.91-7.28 247 ± 4 2.4 ± 1.0 0.999 2.6E-10 0.82 ± 0.0 

Desorption 

Speyer 2.2 Loamy sand (2.1% OC, pH 6.4) 

5.3 ± 

0.2 0.998 0.030 5.07-5.57 253 ± 12 0.002 ± 1.0 1.0 N/A -2.3 ± 0.0 

Pavia Loamy sand (0.5% OC, pH 5.2) 

7.7 ± 

0.0 0.999 0.003 7.70-7.77 1547 ± 7 680.6 ± 1.0 1.0 N/A 2.9 ± 0.0 

Drummer Silt loam (3.1% OC, pH 5.5) 

160.2 ± 

5.8 0.999 0.023 154.63- 166.24 5168 ± 187 0.8 ± 1.0 1.0 N/A -0.9 ± 0.0 
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

5 of 31 

Soil/ Sediment, % OC pH 

Regressed Kd

(L/kg-soil) Range of 

Kd (L/kgsoil) 

Regressed 

KOC (L/kgOC) 

KF 

((L/kg-soil)-1/n)

1/n for 

adsorption 

(

Value ± 

SE r2 p-value Value ± SE Value ± SE r2 p-value Value ± SE 

Nambsheim Sandy loam (0.7% OC, pH 7.8) 

3.0 ± 

0.0 0.999 0.005 3.01-3.06 434 ± 4 7.5 ± 1.0 1.0 N/A 1.4 ± 0.0 

Vercelli Silt loam (1.2% OC, pH 5.8) 

7.5 ± 

0.1 0.999 0.008 7.42-7.60 625 ± 8 0.7 ± 1.0 1.0 N/A -0.1 ± 0.0 

Abbreviations: SE = standard error of regression. A Data were obtained from Tables 5-9, pp. 33-37 and Tables 12-16, pp. 40-44 of the study report and DER Attachment. Data and result

workbook. See Attachment 3 for equations used for calculations. N/A = Not applicable. 
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

6 of 31 

I. Material and Methods 

A. Materials 

1. Test Material: [Pyrimidine-2-14C]IN-J0290 (p. 15) 

 Batch/Lot number: 0318

Specific radioactivity: 141.8 μCi/mg (314800 dpm/μg) 

 Radiochemical purity: >95.0% (by HPLC; p. 25; Appendix 1, pp. 

55-56) 

 Purity: Not reported 

 Solubility in water: Not reported 

2. Reference 

Compounds: IN-J0290 (p. 15) 

 Batch/Lot number: 1423 

 Purity: 99.6% 

3. Soils/Sediment: The study was conducted using four European test soils and one 

U.S. soil (p. 16; Table 1, p. 29). Pesticide use history at the collection sites and soil 

collection depths were not reported. The soils were stored at ca. 4C. All soils were 

sieved (2-mm) and air-dried prior to use. A summary of the physical and chemical 

properties of the soils using USDA Soil Taxonomy is provided in Table 2. The U.S. 

test soils were representative of use sites. 
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

7 of 31 

Table 2. Description of Soil/Sediment 

Soil Name 

Origin 

Speyer 2.2 

Speyer 

Institute, 

Germany 

Pavia 

Ottobiano, 

Italy 

Drummer 

Rochelle, 

Illinois, USA 

Nambsheim 

Nambsheim, 

France 

Vercelli 

Bianze, Italy 

USDA Textural 

Class 

Loamy sand Loamy sand Silt loam Sandy loam Silt loam 

% Sand 69.2 78.4 16.8 57.2 20.4 

% Silt 24.8 14.8 54.4 32.8 62.8 

% Clay 6.0 6.8 28.8 10.0 16.8 

%OC 2.1 0.5 3.1 0.7 1.2 

CEC (meq/100 cc) 10.67 2.59 34.05 6.48 8.45 

pH in water 6.4 5.2 5.5 7.8 5.8 

% moisture (1/3 

bar) 

Not reported Not reported Not reported Not reported Not reported 

Water holding 

capacity (g/100 g) 

Not reported Not reported Not reported Not reported Not reported 

Soil Taxonomy Not reported Not reported Not reported Not reported Not reported 

CaCO3 (%) Not reported Not reported Not reported Not reported Not reported 

Data were obtained from p. 16 and Table 1, p. 29 of the study report. 

B. Study design

1. Experimental conditions: Preliminary pilot tests were conducted to determine 

the optimum soil:solution ratio and equilibrium times to be used in the definitive 

study and to determine the volume of supernatant to be removed and added 

following equilibration (pp. 17-18). The appropriate soil:solution ratio to be used 

in the definitive study was determined using duplicate aliquots of soil (10 g dry 

weight) that were pre-equilibrated by shaking at ca. 20-22C for ca. 18 hours in 

darkness with 0.01M CaCl2 solution at a soil:solution ratio of 1:2 (w:v). The 

slurries were dosed with treatment solution to establish a nominal concentration 

of ca. 1 μg/mL. The samples were shaken for ca. 24 hours in darkness at ca. 20-

22C, centrifuged, and the supernatants were removed prior to analysis using 

LSC. The experiment was repeated for the Drummer soil at soil:solution ratios of 

1:10 (w:v; 2 g dry weight equivalent of soil) and 1:20 (w:v; 1 g dry weight 

equivalent of soil) due to unacceptably high levels of test substance adsorption to 

the soil. Based on the results, a soil:solution ratio of 1:20 (w:v) was selected for 

the Drummer silt loam soil and 1:2 (w:v) was selected for the remaining test soils 

(p. 25). 

The volume of supernatant to be removed and added following equilibration was 

determined using triplicate samples of each soil (10 g dry weight equivalent) at 

soil:solution ratios of 1:2 (w:v), except for the Drummer soil where a 1:20 (w:v) 

ratio was used (p. 18). Aqueous 0.01M CaCl2 solution was added to each sample 

to achieve a final volume of 20 mL. The samples were shaken for 24 hours in 

darkness at ca. 20-22C, centrifuged, and the supernatants were removed and 

measured. A mean of the volumes removed for each soil type was calculated. 
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

8 of 31 

The equilibrium period to be used in the definitive study was determined using six 

samples of each soil (10 g dry weight equivalent) at soil:solution ratios of 1:2 

(w:v), except for the Drummer soil for which a 1:20 (w:v) ratio was used (pp. 18-

19). Aqueous 0.01M CaCl2 solution was added to each sample to achieve a final 

volume of 19 mL. The samples were pre-equilibrated by shaking for ca. 18 hours 

in darkness at ca. 20-22C. The slurries were dosed with treatment solution to 

establish a nominal concentration of ca. 1 μg/mL. The samples were shaken in 

darkness at ca. 20-22C. After 0.5, 2, 4, 8, 24, and 48 hours, the samples were 

centrifuged and the supernatants were removed prior to analysis using LSC. The 

24-hour supernatants were extracted by shaking once with acetonitrile, twice with 

acetonitrile:water (4:1, v:v), and once with acetonitrile:water (1:1, v:v). The 

extracts were analyzed using LSC. The remaining soils were air-dried and 

analyzed using LSC following combustion. The stability of the test substance was 

assessed by analyzing 24-hour samples using TLC. Adsorption of the test 

substance to the test containers was assessed by shaking test solutions at the 

highest and lowest test concentrations in tubes without soil for 24 hours at 20-

22C and analyzing using LSC. Based on the results, an equilibrium time of 24 

hours was selected for use in the definitive study (pp. 25-26). IN-J0290 was 

shown to be stable, accounting for 82.8-96.2% in both the supernatants and soil 

extracts (Appendix 3, Table 5, p. 60). No significant adsorption of radioactivity to 

the glass surface of the test containers was observed (Appendix 3, Table 6, p. 60). 

For the definitive study, duplicate aliquots of each soil were pre-equilibrated by 

shaking in the dark for ca. 18 hours at ca. 20-22C with 0.01M CaCl2 solution 

(pp. 20-21). The soil:solution ratios used in the study were 1:20 (w:v; Drummer 

silt loam only) and 1:2 (w:v). The samples were dosed with IN-J0290 at a 

nominal concentration range of 0.01 to 1.0 μg/mL. The samples were maintained 

at ca. 20-22C in the dark for 24 hours. Following centrifugation, aliquots of the 

supernatants were removed and subjected to solvent extraction. For desorption, an 

equivalent volume of fresh 0.01M aqueous CaCl2 solution was added to each test 

vessel from the highest initial concentration only, and the samples were 

equilibrated by shaking for 24 hours in the dark at ca. 20-22C. Following 

centrifugation, the desorption step was repeated. Following centrifugation, 

aliquots of the supernatants were removed and subjected to solvent extraction. 

2. Analytical procedures: Radioactivity in the aqueous supernatants was 

determined by Liquid Scintillation Counting (LSC; pp. 20-21). Aqueous solutions 

were extracted by shaking once with acetonitrile, twice with acetonitrile:water 

(4:1, v:v), and once with acetonitrile:water (1:1, v:v; p. 19). The extracts were 

analyzed using LSC. Non-extractable residues were measured by combustion and 

LSC. 

Representative extracts and supernatants were pooled (10% by volume) and 

analyzed by normal phase TLC (Merck Kieselgel 60 254F; 0.25 mm thickness) 

using plates that were developed in dichloromethane:methanol:ammonia 
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

9 of 31 

(180:30:1, v:v:v; p. 22). Radioactive areas were detected using a Fuji BAS 2000 

Bioimaging analyzer. 

Radioactivity in amounts of less than twice the background levels were generally 

considered to be below the Limit of Detection (LOD; p. 21). 

II. Results and Discussion 

A. Mass Balance: Overall recovery was determined only for soils that were treated 

at the highest test concentration. Recoveries were 97.0% of the applied for the 

Speyer 2.2 loamy sand, 100.6% for the Pavia loamy sand, 98.1% for the silt loam, 

100.2% for the Nambsheim sandy loam, and 100.3% for the Vercelli silt loam (p. 

27; Table 10, p. 38). 

B. Transformation of Parent Compound: TLC analysis of high-dose aqueous 

supernatants and soil extracts showed that [14C]IN-J0290 was stable following the 

adsorption phase, accounting for ≥93.3% of the radioactivity (pp. 26-27; Table 3, 

p. 31; Table 11, p. 39; Figures 1-5, pp. 45-49). Following the second desorption 

step, [14C]IN-J0290 accounted for ≥89.1% of the radioactivity in the high-dose 

aqueous supernatants and soil extracts. “Other” unidentified radioactivity 

accounted for ≤10.9%. 

C. Findings: Reported values were calculated using linear regression (Excel) and the 

equations and methods discussed in the calculations section. 

Following the adsorption phase, equilibration concentrations in water were 

appropriate for all treated soils, ranging from 0.0004-0.5991 μg/mL (Tables 5-9, pp. 

33-37). Following the second desorption step, equilibration concentrations in water 

were determined only for soils treated at the highest concentration. The 

concentrations were appropriate for all treated soils, ranging from 0.0631-0.1031 

μg/mL (Tables 12-16, pp. 40-44). 

Percent adsorption was not reported. Percent desorption, as percent of the adsorbed, 

ranged from 21 to 47% of the applied for all test soils (p. 28). 

Coefficients of variation (CV) were 1.9 to 1.3 across all [14C]-treated soils for 

adsorption KF and KFoc, respectively, and 2.2 and 2.2 across all [14C]-treated soils for 

desorption KF and KFoc, respectively. 

Table 3. Description of Adsorption Coefficients 

Soil Kd (L/kg) Koc KF (L/kg) KFoc

Speyer 2.2 Loamy sand 1.4 66 1.2 59 

Pavia Loamy sand 2.8 560 2.3 452 

Drummer Silt loam 69.8 2251 45.2 1458 

Nambsheim Sandy loam 0.9 135 0.9 122 

Vercelli Silt loam 3.0 247 2.4 197 
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

10 of 31 

Data were obtained from DER Attachment. 

Table 4. Description of Desorption Coefficients 

Soil Kdes (L/kg) Koc-des KFdes (L/kg) KFoc-des

Speyer 2.2 Loamy sand 5.3 253 0.002 0 

Pavia Loamy sand 7.7 1547 680.6 136117 

Drummer Silt loam 160.2 5168 0.799 26 

Nambsheim Sandy loam 3.0 434 7.455 1065 

Vercelli Silt loam 7.5 625 0.662 55 

 Data were obtained from DER Attachment. 

Reviewer-calculated Freundlich adsorption coefficients were in agreement with those 

reported by the study author (Table 4, p. 32). Reviewer-calculated Freundlich 

desorption coefficients varied from those reported by the study author (Tables 12-16, 

pp. 40-44). These values were calculated using only soils treated at the highest test 

concentration. 

y = 1.3925x

r2 = 0.9926

0.0

0.2

0.4

0.6

0.8

IN-J0290 Concentration in Speyer 2.2 Loamy 

0.0 0.1 0.2 0.3 0.4 0.5 0.6

Sand- Adsorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

11 of 31 

y = 2.7997x

r2 = 0.9928

0.0

0.3

0.6

0.9

1.2

0.0 0.1 0.2 0.3 0.4

IN-J0290 Concentration in Pavia Loamy 

Sand- Adsorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)

y = 69.77x

r2 = 0.954

0

5

10

15

0.00 0.05 0.10 0.15 0.20 0.25

IN-J0290 Concentration in Drummer Silt 

Loam- Adsorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

12 of 31 

y = 0.9423x

r2 = 0.9738

0.0

0.1

0.2

0.3

0.4

0.5

0.6

0.0 0.1 0.2 0.3 0.4 0.5 0.6

IN-J0290 Concentration in Nambsheim Sandy 

Loam- Adsorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)

y = 2.964x

r2 = 0.9955

0.0

0.3

0.6

0.9

1.2

IN-J0290 Concentration in Vercelli Silt Loam0.0 0.1 0.2 0.3 0.4 Adsorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

13 of 31 

y = 5.3138x

r2 = -1.036

0.0

0.1

0.2

0.3

0.4

0.5

0.00 0.02 0.04 0.06 0.08 0.10

IIN-J0290 Concentration in Speyer 2.2 

Loamy Sand- Desorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)

y = 7.7327x

r2 = 0.5765

0.0

0.2

0.4

0.6

0.8

1.0

0.00 0.05 0.10 0.15 0.20

IN-J0290 Concentration in Pavia Loamy 

Sand- Desorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

14 of 31 

y = 160.22x

r2 = -3.297

0

5

10

15

0.00 0.01 0.02 0.03 0.04 0.05 0.06 0.07 0.08

IN-J0290 Concentration in Drummer Silt 

Loam- Desorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)

y = 3.0367x

r2 = 0.9274

0.0

0.1

0.2

0.3

0.00 0.02 0.04 0.06 0.08 0.10

IN-J0290 Concentration in Nambsheim 

Sandy Loam- Desorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

15 of 31 

y = 7.5051x

r2 = -277.7

0.0

0.2

0.4

0.6

0.8

0.00 0.05 0.10 0.15

IN-J0290 Concentration in Vercelli Silt 

Loam- Desorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)

The results of the regression of Kd by percent organic carbon, CEC, and percent clay 

are tabulated below: 

Table 5. Summary of Regressed Kd vs %OC, CEC, and %Clay

Parameter r2 p-value 

Kd vs. % organic carbon 0.664 0.093 

Kd vs. % clay 0.807 0.038 

Kd vs. CEC 0.937 0.007 

The data indicate a significant correlation between the adsorption of IN-J0290 to soil 

and cation exchange capacity (r2

 = 0.937) and percent clay (r2 = 0.807). The 

correlation between adsorption of IN-J0290 to soil and percent organic carbon was 

less pronounced (r2 = 0.664; DER Attachment). 

y = 0.029x + 1.0688

r2 = 0.6637

0

1

2

3

4

0 25 50 75

Percent Organic carbon

Kd (L/kg)
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

16 of 31 

y = 0.2805x + 9.3115

r2 = 0.8072

0

10

20

30

0 25 50 75

Percent Clay

Kd (L/kg)

y = 0.3972x + 6.2618

r2 = 0.9373

0

10

20

30

0 25 50 75

Cation Exchange Capacity (meq/100 

g)

Kd (L/kg)

III. Study Deficiencies and Reviewer’s Comments 

1. The study was conducted using a transformation product rather than the parent 

compound. 

2. The study was conducted using only three types of soil (loamy sand, silt loam, 

and sandy loam). OCSPP guidelines recommend that at least 5 soils/sediments of 

different textures are examined. 

3. Mass balances were determined for soils treated at the highest test concentration, 

rather across all test concentrations. 

4. The desorption phase of the experiment was conducted using the highest test 

concentration only, rather than all five test concentrations. The reviewer 

determined desorption K values based on the highest test concentration desorption 

data; however, these values are of limited value since only one test concentration 

was employed. As with adsorption kinetics/adsorption isotherms, desorption 
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

17 of 31 

kinetics/desorption isotherms should be conducted using five test substance 

concentrations, covering preferably two orders of magnitude. 

IV. References 

1. U.S. Environmental Protection Agency. 2008. Fate, Transport and Transformation 

Test Guidelines, OPPTS 835.1230, adsorption/desorption (batch equilibrium). Office 

of Prevention, Pesticides and Toxic Substances, Washington, DC. EPA 712-C-08-

019. 
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

18 of 31 

DER ATTACHMENT 1. IN-J0290 and Its Environmental Transformation Products. 

A

Code Name/ Synonym Chemical Name Chemical Structure Study Type MRID Max

%AR 

PARENT

IN-J0290 IUPAC: 4,6-Dimethoxy-pyrimidin2-ylamine 

CAS: 2-Amino-4,6-dimethoxypyrimidine CAS No.: 36315-01-2 Formula: C6H9N3O2

MW: 155.15 g/mol

SMILES: Nc1nc(cc(n1)OC)OC 

835.1230 

Batch 

equilibrium 

49169701 N

MAJOR (>10%) TRANSFORMATION PRODUCTS 

No major transformation products were identified.

MINOR (<10%) TRANSFORMATION PRODUCTS

No minor transformation products were identified.

REFERENCE COMPOUNDS NOT IDENTIFIED 

All compounds used as reference compounds were identified.

A AR means “applied radioactivity”. MW means “molecular weight”. NA means "not applicable".
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

19 of 31 

Attachment 2: Calculations 

Chemical: IN-J0290

PC Code: 129008

MRID: 49169701

Guideline No: 835.1230

Reviewer-calculated Adsorption Kd values

1 0.5131 0.6761 1.32

1 0.4994 0.7033 1.41

0.5 0.2265 0.3492 1.54

0.5 0.2289 0.3445 1.51

0.1 0.0383 0.0716 1.87

0.1 0.0365 0.0751 2.06

0.05 0.0156 0.0409 2.62

0.05 0.0162 0.0397 2.45

0.01 0.0036 0.0093 2.58

0.01 0.0035 0.0095 2.71

Data were obtained from Table 5, p. 33 of the study report.

SUMMARY OUTPUT

Regression Statistics

Multiple R 0.997939891

R Square 0.995884027

Adjusted R Square 0.884772915

Standard Error 0.023490303

Observations 10

ANOVA

df SS MS F Significance F

Regression 1 1.201589051 1.201589051 2177.60304 4.91552E-11

Residual 9 0.004966149 0.000551794

Total 10 1.2065552

Coefficients Standard Error t Stat P-value Lower 95% Upper 95% Lower 95.0% Upper 95.0%

Intercept 0 #N/A #N/A #N/A #N/A #N/A #N/A #N/A

X Variable 1 1.392474915 0.029839945 46.66479446 4.7713E-12 1.324972269 1.459977561 1.324972269 1.459977561

Speyer 2.2 Loamy sand

Initial soln concen (Co) (mg/L)

Concen in soln at 

ads equil (Ceq) 

(μg/mL)

Concen in soil at 

ads equil (Cs) 

(μg/g)

Kd

y = 1.3925x

r2 = 0.9926

0.0

0.2

0.4

0.6

0.8

0.0 0.1 0.2 0.3 0.4 0.5 0.6

IN-J0290 Concentration in Speyer 2.2 

Loamy Sand- Adsorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

20 of 31 

Chemical: IN-J0290

PC Code: 129008

MRID: 49169701

Guideline No: 835.1230

Reviewer-calculated Adsorption Kd values

1 0.3651 1.019 2.79

1 0.3719 1.005 2.70

0.5 0.1654 0.4937 2.98

0.5 0.1629 0.4986 3.06

0.1 0.0223 0.1078 4.83

0.1 0.0219 0.1085 4.95

0.05 0.0093 0.0556 5.98

0.05 0.0089 0.0564 6.34

0.01 0.0019 0.0132 6.95

0.01 0.0019 0.0133 7.00

Data were obtained from Table 6, p. 34 of the study report.

SUMMARY OUTPUT

Regression Statistics

Multiple R 0.997986181

R Square 0.995976418

Adjusted R Square 0.884865307

Standard Error 0.033901163

Observations 10

ANOVA

df SS MS F Significance F

Regression 1 2.56040059 2.56040059 2227.81297 4.48847E-11

Residual 9 0.0103436 0.001149289

Total 10 2.57074419

Coefficients Standard Error t Stat P-value Lower 95% Upper 95% Lower 95.0% Upper 95.0%

Intercept 0 #N/A #N/A #N/A #N/A #N/A #N/A #N/A

X Variable 1 2.799702961 0.059316101 47.19971368 4.3078E-12 2.66552062 2.933885303 2.66552062 2.933885303

Pavia Loamy sand

Initial soln concen (Co) (mg/L)

Concen in soln at 

ads equil (Ceq) 

(μg/mL)

Concen in soil at 

ads equil (Cs) 

(μg/g)

Kd

y = 2.7997x

r2 = 0.9928

0.0

0.3

0.6

0.9

1.2

0.0 0.1 0.2 0.3 0.4

IN-J0290 Concentration in Pavia Loamy 

Sand- Adsorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

21 of 31 

Chemical: IN-J0290

PC Code: 129008

MRID: 49169701

Guideline No: 835.1230

Reviewer-calculated Adsorption Kd values

1 0.1898 13.1 69.02

1 0.2018 12.87 63.78

0.5 0.0671 6.616 98.60

0.5 0.0676 6.607 97.74

0.1 0.0061 1.347 220.82

0.1 0.0061 1.334 218.69

0.05 0.0022 0.6706 304.82

0.05 0.0021 0.6663 317.29

0.01 0.0005 0.1538 307.60

0.01 0.0004 0.1565 391.25

Data were obtained from Table 7, p. 35 of the study report.

SUMMARY OUTPUT

Regression Statistics

Multiple R 0.987052925

R Square 0.974273478

Adjusted R Square 0.863162366

Standard Error 1.107649795

Observations 10

ANOVA

df SS MS F Significance F

Regression 1 418.1645841 418.1645841 340.833524 7.63429E-08

Residual 9 11.04199261 1.226888067

Total 10 429.2065767

Coefficients Standard Error t Stat P-value Lower 95% Upper 95% Lower 95.0% Upper 95.0%

Intercept 0 #N/A #N/A #N/A #N/A #N/A #N/A #N/A

X Variable 1 69.76990294 3.779174678 18.46167718 1.837E-08 61.22081587 78.31899 61.22081587 78.31899

Drummer Silt loam

Initial soln concen (Co) (mg/L)

Concen in soln at 

ads equil (Ceq) 

(μg/mL)

Concen in soil at 

ads equil (Cs) 

(μg/g)

Kd

y = 69.77x

r2 = 0.954

0

5

10

15

0.00 0.05 0.10 0.15 0.20 0.25

IN-J0290 Concentration in Drummer Silt 

Loam- Adsorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

22 of 31 

Chemical: IN-J0290

PC Code: 129008

MRID: 49169701

Guideline No: 835.1230

Reviewer-calculated Adsorption Kd values

1 0.5966 0.5395 0.90

1 0.5991 0.5347 0.89

0.5 0.2601 0.2944 1.13

0.5 0.2568 0.301 1.17

0.1 0.0391 0.0716 1.83

0.1 0.0397 0.0705 1.78

0.05 0.0175 0.0378 2.16

0.05 0.0176 0.0377 2.14

0.01 0.0036 0.0094 2.61

0.01 0.0037 0.0093 2.51

Data were obtained from Table 8, p. 36 of the study report.

SUMMARY OUTPUT

Regression Statistics

Multiple R 0.993074883

R Square 0.986197723

Adjusted R Square 0.875086612

Standard Error 0.034304672

Observations 10

ANOVA

df SS MS F Significance F

Regression 1 0.756767196 0.756767196 643.066322 6.26416E-09

Residual 9 0.010591294 0.00117681

Total 10 0.76735849

Coefficients Standard Error t Stat P-value Lower 95% Upper 95% Lower 95.0% Upper 95.0%

Intercept 0 #N/A #N/A #N/A #N/A #N/A #N/A #N/A

X Variable 1 0.94234699 0.037160621 25.35875238 1.1092E-09 0.858283825 1.026410156 0.858283825 1.026410156

Nambsheim Sandy loam

Initial soln concen (Co) (mg/L)

Concen in soln at 

ads equil (Ceq) 

(μg/mL)

Concen in soil at 

ads equil (Cs) 

(μg/g)

Kd

y = 0.9423x

r2 = 0.9738

0.0

0.1

0.2

0.3

0.4

0.5

0.6

0.0 0.1 0.2 0.3 0.4 0.5 0.6

IN-J0290 Concentration in Nambsheim 

Sandy Loam- Adsorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

23 of 31 

Chemical: IN-J0290

PC Code: 129008

MRID: 49169701

Guideline No: 835.1230

Reviewer-calculated Adsorption Kd values

1 0.3509 1.029 2.93

1 0.3528 1.025 2.91

0.5 0.1588 0.4975 3.13

0.5 0.1583 0.4985 3.15

0.1 0.0216 0.1068 4.94

0.1 0.0227 0.1046 4.61

0.05 0.0096 0.0538 5.60

0.05 0.0099 0.0533 5.38

0.01 0.0018 0.0131 7.28

0.01 0.0018 0.013 7.22

Data were obtained from Table 9, p. 37 of the study report.

SUMMARY OUTPUT

Regression Statistics

Multiple R 0.998729904

R Square 0.997461422

Adjusted R Square 0.886350311

Standard Error 0.027256712

Observations 10

ANOVA

df SS MS F Significance F

Regression 1 2.627211485 2.627211485 3536.29194 7.10383E-12

Residual 9 0.006686355 0.000742928

Total 10 2.63389784

Coefficients Standard Error t Stat P-value Lower 95% Upper 95% Lower 95.0% Upper 95.0%

Intercept 0 #N/A #N/A #N/A #N/A #N/A #N/A #N/A

X Variable 1 2.963965108 0.04984241 59.46672966 5.4186E-13 2.851213743 3.076716472 2.851213743 3.076716472

Vercelli Silt loam

Initial soln concen (Co) (mg/L)

Concen in soln at 

ads equil (Ceq) 

(μg/mL)

Concen in soil at 

ads equil (Cs) 

(μg/g)

Kd

y = 2.964x

r2 = 0.9955

0.0

0.3

0.6

0.9

1.2

0.0 0.1 0.2 0.3 0.4

IN-J0290 Concentration in Vercelli Silt 

Loam- Adsorption Phase (mg/kg)

Pesticide Concentration in Water at Equilibrium (mg/L)
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

24 of 31 

Chemical: IN-J0290

PC Code: 129008

MRID: 49169701

Guideline No: 835.1230

Reviewer-calculated Adsorption KF values

1 0.5131 -0.290 0.6761 -0.169989064

1 0.4994 -0.302 0.7033 -0.152859383

0.5 0.2265 -0.645 0.3492 -0.456925765

0.5 0.2289 -0.640 0.3445 -0.462810774

0.1 0.0383 -1.417 0.0716 -1.145086978

0.1 0.0365 -1.438 0.0751 -1.124360063

0.05 0.0156 -1.807 0.0409 -1.388276692

0.05 0.0162 -1.790 0.0397 -1.401209493

0.01 0.0036 -2.444 0.0093 -2.031517051

0.01 0.0035 -2.456 0.0095 -2.022276395

Data were obtained from Table 5, p. 33 of the study report.

SUMMARY OUTPUT

SE

Regression Statistics KF: 1.247118411 1.046777069

Multiple R 0.999086036 1/n: 0.855327657 0.012937935

R Square 0.998172907

Adjusted R Square 0.99794452

Standard Error 0.031825156

Observations 10

ANOVA

df SS MS F Significance F

Regression 1 4.426659865 4.426659865 4370.539846 3.04943E-12

Residual 8 0.008102724 0.001012841

Total 9 4.43476259

Coefficients Standard Error t Stat P-value Lower 95% Upper 95% Lower 95.0% Upper 95.0%

Intercept 0.095907691 0.0198542 4.830599583 0.001303636 0.050123823 0.14169156 0.050123823 0.141691558

X Variable 1 0.855327657 0.012937935 66.11005859 3.04943E-12 0.825492725 0.88516259 0.825492725 0.885162589

Speyer 2.2 Loamy sand

Initial soln concen (Co) (mg/L)

Concen in soln at 

ads equil (Ceq) 

(μg/mL)

Log Ceq (ug/mL)

Concen in soil at 

ads equil (Cs) 

(μg/g)

Log Cs (μg/g)

y = 1.2471x0.8553

r2 = 0.9982

0.0

0.2

0.4

0.6

0.8

0.0 0.1 0.2 0.3 0.4 0.5 0.6

Cs

Ceq
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

25 of 31 

Chemical: IN-J0290

PC Code: 129008

MRID: 49169701

Guideline No: 835.1230

Reviewer-calculated Adsorption KF values

1 0.3651 -0.438 1.019 0.008174184

1 0.3719 -0.430 1.005 0.002166062

0.5 0.1654 -0.781 0.4937 -0.306536873

0.5 0.1629 -0.788 0.4986 -0.302247726

0.1 0.0223 -1.652 0.1078 -0.967381239

0.1 0.0219 -1.660 0.1085 -0.964570262

0.05 0.0093 -2.032 0.0556 -1.254925208

0.05 0.0089 -2.051 0.0564 -1.248720896

0.01 0.0019 -2.721 0.0132 -1.879426069

0.01 0.0019 -2.721 0.0133 -1.876148359

Data were obtained from Table 6, p. 34 of the study report.

SUMMARY OUTPUT

SE

Regression Statistics KF: 2.261076321 1.049822163

Multiple R 0.999096529 1/n: 0.807510691 0.012144224

R Square 0.998193875

Adjusted R Square 0.997968109

Standard Error 0.031917052

Observations 10

ANOVA

df SS MS F Significance F

Regression 1 4.504043264 4.504043264 4421.371428 2.91181E-12

Residual 8 0.008149586 0.001018698

Total 9 4.51219285

Coefficients Standard Error t Stat P-value Lower 95% Upper 95% Lower 95.0% Upper 95.0%

Intercept 0.354315222 0.021115737 16.7796757 1.61115E-07 0.305622245 0.4030082 0.305622245 0.403008199

X Variable 1 0.807510691 0.012144224 66.49339387 2.91181E-12 0.779506059 0.83551532 0.779506059 0.835515322

Pavia Loamy sand

Initial soln concen (Co) (mg/L)

Concen in soln at 

ads equil (Ceq) 

(μg/mL)

Log Ceq (ug/mL)

Concen in soil at 

ads equil (Cs) 

(μg/g)

Log Cs (μg/g)

y = 2.2611x0.8075

r2 = 0.9982

0.0

0.3

0.6

0.9

1.2

0.0 0.1 0.2 0.3 0.4

Cs

Ceq
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

26 of 31 

Chemical: IN-J0290

PC Code: 129008

MRID: 49169701

Guideline No: 835.1230

Reviewer-calculated Adsorption KF values

1 0.1898 -0.722 13.1 1.117271296

1 0.2018 -0.695 12.87 1.109578547

0.5 0.0671 -1.173 6.616 0.820595497

0.5 0.0676 -1.170 6.607 0.820004307

0.1 0.0061 -2.215 1.347 0.129367596

0.1 0.0061 -2.215 1.334 0.12515583

0.05 0.0022 -2.658 0.6706 -0.173536451

0.05 0.0021 -2.678 0.6663 -0.176330187

0.01 0.0005 -3.301 0.1538 -0.813043665

0.01 0.0004 -3.398 0.1565 -0.805485658

Data were obtained from Table 7, p. 35 of the study report.

SUMMARY OUTPUT

SE

Regression Statistics KF: 45.20571569 1.114996633

Multiple R 0.996507728 1/n: 0.711951728 0.021091838

R Square 0.993027651

Adjusted R Square 0.992156108

Standard Error 0.064442421

Observations 10

ANOVA

df SS MS F Significance F

Regression 1 4.731686027 4.731686027 1139.389526 6.48021E-10

Residual 8 0.033222605 0.004152826

Total 9 4.764908632

Coefficients Standard Error t Stat P-value Lower 95% Upper 95% Lower 95.0% Upper 95.0%

Intercept 1.655193349 0.047273556 35.01309181 4.844E-10 1.546180334 1.76420636 1.546180334 1.764206364

X Variable 1 0.711951728 0.021091838 33.75484448 6.48021E-10 0.663313861 0.76058959 0.663313861 0.760589595

Chemical: IN-J0290

Drummer Silt loam

Initial soln concen (Co) (mg/L)

Concen in soln at 

ads equil (Ceq) 

(μg/mL)

Log Ceq (ug/mL)

Concen in soil at 

ads equil (Cs) 

(μg/g)

Log Cs (μg/g)

y = 45.206x0.712

r2 = 0.993

0

5

10

15

0.00 0.05 0.10 0.15 0.20 0.25

Cs

Ceq
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

27 of 31 

Chemical: IN-J0290

PC Code: 129008

MRID: 49169701

Guideline No: 835.1230

Reviewer-calculated Adsorption KF values

1 0.5966 -0.224 0.5395 -0.268008551

1 0.5991 -0.223 0.5347 -0.271889816

0.5 0.2601 -0.585 0.2944 -0.531062194

0.5 0.2568 -0.590 0.301 -0.521433504

0.1 0.0391 -1.408 0.0716 -1.145086978

0.1 0.0397 -1.401 0.0705 -1.151810883

0.05 0.0175 -1.757 0.0378 -1.4225082

0.05 0.0176 -1.754 0.0377 -1.42365865

0.01 0.0036 -2.444 0.0094 -2.026872146

0.01 0.0037 -2.432 0.0093 -2.031517051

Data were obtained from Table 8, p. 36 of the study report.

SUMMARY OUTPUT

SE

Regression Statistics KF: 0.856961664 1.044212136

Multiple R 0.999007976 1/n: 0.789781139 0.012446896

R Square 0.998016937

Adjusted R Square 0.997769054

Standard Error 0.031379988

Observations 10

ANOVA

df SS MS F Significance F

Regression 1 3.964577827 3.964577827 4026.163515 4.23203E-12

Residual 8 0.007877629 0.000984704

Total 9 3.972455456

Coefficients Standard Error t Stat P-value Lower 95% Upper 95% Lower 95.0% Upper 95.0%

Intercept -0.067038606 0.018788736 -3.568021023 0.007314726 -0.110365509 -0.0237117 -0.11036551 -0.023711702

X Variable 1 0.789781139 0.012446896 63.45205682 4.23203E-12 0.761078546 0.81848373 0.761078546 0.818483732

Nambsheim Sandy loam

Initial soln concen (Co) (mg/L)

Concen in soln at 

ads equil (Ceq) 

(μg/mL)

Log Ceq (ug/mL)

Concen in soil at 

ads equil (Cs) 

(μg/g)

Log Cs (μg/g)

y = 0.857x0.7898

r2 = 0.998

0.0

0.1

0.2

0.3

0.4

0.5

0.6

0.0 0.1 0.2 0.3 0.4 0.5 0.6

Cs

Ceq
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

28 of 31 

Chemical: IN-J0290

PC Code: 129008

MRID: 49169701

Guideline No: 835.1230

Reviewer-calculated Adsorption KF values

1 0.3509 -0.455 1.029 0.012415375

1 0.3528 -0.452 1.025 0.010723865

0.5 0.1588 -0.799 0.4975 -0.303206915

0.5 0.1583 -0.801 0.4985 -0.302334837

0.1 0.0216 -1.666 0.1068 -0.971428747

0.1 0.0227 -1.644 0.1046 -0.980468315

0.05 0.0096 -2.018 0.0538 -1.269217724

0.05 0.0099 -2.004 0.0533 -1.273272791

0.01 0.0018 -2.745 0.0131 -1.882728704

0.01 0.0018 -2.745 0.013 -1.886056648

Data were obtained from Table 9, p. 37 of the study report.

SUMMARY OUTPUT

SE

Regression Statistics KF: 2.360487636 1.022999507

Multiple R 0.999808934 1/n: 0.820431351 0.005671082

R Square 0.999617905

Adjusted R Square 0.999570143

Standard Error 0.014819531

Observations 10

ANOVA

df SS MS F Significance F

Regression 1 4.596438705 4.596438705 20929.19765 5.82922E-15

Residual 8 0.001756948 0.000219618

Total 9 4.598195653

Coefficients Standard Error t Stat P-value Lower 95% Upper 95% Lower 95.0% Upper 95.0%

Intercept 0.37300173 0.009875424 37.77070401 2.64993E-10 0.350228961 0.3957745 0.350228961 0.395774499

X Variable 1 0.820431351 0.005671082 144.6692699 5.82922E-15 0.807353811 0.83350889 0.807353811 0.83350889

Vercelli Silt loam

Initial soln concen (Co) (mg/L)

Concen in soln at 

ads equil (Ceq) 

(μg/mL)

Log Ceq (ug/mL)

Concen in soil at 

ads equil (Cs) 

(μg/g)

Log Cs (μg/g)

y = 2.3605x0.8204

r2 = 0.9996

0.0

0.3

0.6

0.9

1.2

0.0 0.1 0.2 0.3 0.4

Cs

Ceq
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

29 of 31 

Chemical: IN-J0290

PC Code: 129008

MRID: 49169701

Guideline No: 835.1230

Soil Regressed Kd % organic carbon

Speyer 2.2 Loamy sand 1.39 2.1

Pavia Loamy sand 2.80 0.5

Drummer Silt loam 69.77 3.1

Nambsheim Sandy loam 0.94 0.7

Vercelli Silt loam 2.96 1.2

SUMMARY OUTPUT

Regression Statistics

Multiple R 0.814663294

R Square 0.663676283

Adjusted R Square 0.551568378

Standard Error 0.721857011

Observations 5

ANOVA

df SS MS F Significance F

Regression 1 3.084767365 3.084767365 5.919977544 0.093071791

Residual 3 1.563232635 0.521077545

Total 4 4.648

Coefficients Standard Error t Stat P-value Lower 95% Upper 95% Lower 95.0% Upper 95.0%

Intercept 1.068770145 0.372302226 2.870705765 0.064013353 -0.116061697 2.253601988 -0.116061697 2.253601988

X Variable 1 0.028973877 0.011908213 2.433100397 0.093071791 -0.008923371 0.066871125 -0.008923371 0.066871125

Data were obtained from Table 1, p. 29 of the study report. The 

reviewer calculated Kd values using data obtained from Table 5-9, 

pp. 33-37 of the study report.

y = 0.029x + 1.0688

r2 = 0.6637

0

1

2

3

4

0 25 50 75

Percent Organic carbon

Kd (L/kg)
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

30 of 31 

Chemical: IN-J0290

PC Code: 129008

MRID: 49169701

Guideline No: 835.1230

Soil Regressed Kd % clay

Speyer 2.2 Loamy sand 1.39 6

Pavia Loamy sand 2.80 6.8

Drummer Silt loam 69.77 28.8

Nambsheim Sandy loam 0.94 10

Vercelli Silt loam 2.96 16.8

SUMMARY OUTPUT

Regression Statistics

Multiple R 0.898418729

R Square 0.807156213

Adjusted R Square 0.74287495

Standard Error 4.798547954

Observations 5

ANOVA

df SS MS F Significance F

Regression 1 289.1298126 289.1298126 12.55663286 0.038266943

Residual 3 69.07818739 23.02606246

Total 4 358.208

Coefficients Standard Error t Stat P-value Lower 95% Upper 95% Lower 95.0% Upper 95.0%

Intercept 9.311492812 2.474880834 3.762400469 0.032836032 1.435317444 17.18766818 1.435317444 17.18766818

X Variable 1 0.280505801 0.079159902 3.543533951 0.038266943 0.028583663 0.53242794 0.028583663 0.53242794

Data were obtained from Table 1, p. 29 of the study report. The 

reviewer calculated Kd values using data obtained from Table 5-9, 

pp. 33-37 of the study report.

y = 0.2805x + 9.3115

r2 = 0.8072

0

10

20

30

0 25 50 75

Percent Clay

Kd (L/kg)
IN-J0290 (PC 129008 for Nicosulfuron) MRID 49169701 

31 of 31 

Chemical: IN-J0290

PC Code: 129008

MRID: 49169701

Guideline No: 835.1230

Soil Regressed Kd CEC

Speyer 2.2 Loamy sand 1.39 10.67

Pavia Loamy sand 2.80 2.59

Drummer Silt loam 69.77 34.05

Nambsheim Sandy loam 0.94 6.48

Vercelli Silt loam 2.96 8.45

SUMMARY OUTPUT

Regression Statistics

Multiple R 0.968131271

R Square 0.937278157

Adjusted R Square 0.916370876

Standard Error 3.596249649

Observations 5

ANOVA

df SS MS F Significance F

Regression 1 579.7898454 579.7898454 44.83022719 0.006796635

Residual 3 38.79903461 12.93301154

Total 4 618.58888

Coefficients Standard Error t Stat P-value Lower 95% Upper 95% Lower 95.0% Upper 95.0%

Intercept 6.261829015 1.854788035 3.376034833 0.04321768 0.359065685 12.16459235 0.359065685 12.16459235

X Variable 1 0.397219639 0.059326024 6.695537856 0.006796635 0.208417753 0.586021525 0.208417753 0.586021525

Data were obtained from Table 1, p. 29 of the study report. The 

reviewer calculated Kd values using data obtained from Table 5-9, 

pp. 33-37 of the study report.

y = 0.3972x + 6.2618

r2 = 0.9373

0

10

20

30

0 25 50 75

Cation Exchange Capacity 

(meq/100 g)

Kd (L/kg)