UNITED
STATES

SECURITIES
AND EXCHANGE COMMISSION

Washington,
DC 20549












FORM
10-K/A

(Amendment
No. 1)














(Mark
One)





[X]
ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934



For
the fiscal year ended December 31, 2017



OR



[  ]
TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934



For
the transition period from_____ to_____



Commission
File Number: 001-37685










PAVMED
INC.

(Exact
Name of Registrant as Specified in Its Charter)










|Delaware                                                          |  | 47-1214177                          
|----------------------------------------------------------------- |  | ------------------------------------
|(State
    or Other Jurisdiction ofIncorporation or Organization) |  | (IRS
    EmployerIdentification No.)



|One
                                         Grand Central Place60 E. 42nd Street
        Suite
        4600
        New
        York, NY 10165
        (Address
        of Principal Executive Offices) |  | 10165
        (Zip
        Code)
|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |  | --------------------------------



(212)
949-4319(Registrant’s Telephone Number, Including Area Code)










Securities
registered under Section 12(b) of the Exchange Act:



|Title
    of each Class                              |  | Name
    of each Exchange on which Registered
|---------------------------------------------------- |  | ---------------------------------------------
|                                                     |  |                                              
|Common
    Stock, $0.001 par value per share         |  | The
    NASDAQ Stock Market LLC              
|                                                     |  |                                              
|Series
    W Warrants, each to purchase one share of |  |                                              
|Common
    Stock                                     |  | The
    NASDAQ Stock Market LLC              



Securities
registered under Section 12(g) of the Exchange Act: None



Indicate
by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Yes [  ] No [X]



Indicate
by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Exchange Act. Yes [  ] No [X]



Indicate
by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange
Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports),
and (2) has been subject to such filing requirements for the past 90 days. Yes [X] No [  ]



Indicate
by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive
Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the
preceding 12 months (or for such shorter period that the registrant was required to submit and post such files). Yes [X]
No [  ]



Indicate
by check mark if disclosure of delinquent files pursuant to Item 405 of Regulation S-K (§229.405) is not contained herein,
and will not be contained, to the best of the registrant’s knowledge, in definitive proxy or information statements incorporated
by reference in Part III of this Form 10-K or any amendment to this Form 10-K. [  ]



Indicate
by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller
reporting company. See the definitions of  “large accelerated filer”, “accelerated filer” and “smaller
reporting company” in Rule 12b-2 of the Exchange Act.



|Large
    accelerated filer                       | [  ] |  | Accelerated
    filer             | [  ]
|------------------------------------------------- | ---- |  | --------------------------------- | ----
|Non-accelerated
    filer                         | [  ] |  | Smaller
    reporting company     | [X] 
|(Do
    not check if a smaller reporting company) |      |  | Emerging
    Growth Company (EGC) | [X] 



Indicate
by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes [  ] No [X]



As
of June 30, 2017, the last business day of the registrant’s most recently completed second fiscal quarter, the aggregate
market value of the registrant’s voting stock held by non-affiliates was approximately $21.3million, based on the last reported
sales price per share of the registrant’s common stock on such date.



As
of April 25, 2018, there were 17,509,654 shares of the registrant’s Common Stock, par value $0.001 per share, issued and
outstanding.



DOCUMENTS
INCORPORATED BY REFERENCE

None.


















EXPLANATORY
NOTE



PAVmed
Inc. (“PAVmed” or “the Company”) is filing this Amendment No. 1 on Form 10-K/A (“Form 10-K Amendment”)
to amend its Annual Report on Form 10-K for the year ended December 31, 2017, previously filed with the Securities and Exchange
Commission (“SEC”) on March 14, 2018 (“Form 10-K”).



This
Form 10-K Amendment is being filed to: (i) include the information required by Items 10 through 14 of Part III of Form 10-K; (ii)
to amend the cover page of the previously filed Form 10-K to (a) delete the reference in the previously filed Form 10-K to the
incorporation by reference of the definitive Proxy Statement for our 2018 Annual Meeting of Shareholders and (b) update the number
of outstanding shares of common stock; and (iii) amend Item 15 of the previously filed Form 10-K to include the certifications
specified in Rule 13a-14(a) under the Securities Exchange Act of 1934, required to be filed with this Form 10-K Amendment. Except
as set forth in the immediately preceding sentence, this Form 10-K Amendment does not amend, modify, or update any disclosures
contained in the previously filed Form 10-K. Nothing contained in this Form 10-K Amendment updates any disclosure contained in
the Original Form 10-K to reflect any events occurring after the filing of the Original Form 10-K.











TABLE
OF CONTENTS



|             | PART
    III                                                                                       |   
|------------ | -------------------------------------------------------------------------------------------------- | --
|Item
    10. | Directors,
    Executive Officers, and Corporate Governance                                        | 1 
|Item
    11. | Executive
    Compensation                                                                         | 9 
|Item
    12. | Security
    Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters | 18
|Item
    13. | Certain
    Relationships and Related Transactions and Director Independence                       | 20
|Item
    14. | Principal
    Accountant Fees and Services                                                         | 23
|             |                                                                                                    |   
|             | PART
    IV                                                                                        |   
|Item
    15. | Exhibits
    and Financial Statement Schedules                                                     | 24
|Item
    16  | Form
    10-K Summary                                                                              | 26



i







PART
III



Item
10. Directors, Executive Officers and Corporate Governance



The
following table sets forth the name, age and position of each of our executive officers, key employees and directors as of April
25, 2018.



|Name                         |  | Age |  | Position                                                                  
|---------------------------- |  | --- |  | --------------------------------------------------------------------------
|Lishan
    Aklog, M.D.       |  | 52  |  | Chairman
    and Chief Executive Officer                                  
|Dennis
    M. McGrath        |  | 61  |  | Executive
    Vice President, Chief Financial Officer, Corporate Secretary
|Michael
    J. Glennon       |  | 52  |  | Vice
    Chairman and Director                                            
|Brian
    J. deGuzman, M.D.  |  | 54  |  | Chief
    Medical Officer                                                 
|Ronald
    M. Sparks         |  | 63  |  | Director                                                                  
|James
    L. Cox, M.D.       |  | 75  |  | Director                                                                  
|David
    S. Battleman, M.D. |  | 51  |  | Director                                                                  
|David
    Weild IV           |  | 61  |  | Director                                                                  



Lishan
Aklog, M.D., has been the Company’s Chairman and Chief Executive Officer since its inception. Dr. Aklog has also served
as a member of the board of directors of HCFP, Inc., a financial advisory and investment firm, since its inception, and as a co-founding
Partner of both Pavilion Holdings Group (“PHG”), a medical device holding company, since its inception in 2007 and
Pavilion Medical Innovations (“PMI”), a venture-backed medical device incubator, since its inception in 2009. Dr.
Aklog previously served as Chairman and Chief Technology Officer of Vortex Medical Inc., a PHG portfolio company, from its inception
in 2008 until its acquisition in October 2012 by AngioDynamics Inc. (Nasdaq: ANGO) for $55 million. Dr. Aklog has been a consultant
to AngioDynamics since 2012 and to Biomet Inc. since 2009. He previously served as a consultant to Edward Lifesciences
Corp. (NYSE: EW), from 2007 to 2012, On-X Life Technologies Inc. from 2009 to 2012 and Atricure Inc. (Nasdaq: ATRC) from 2007
to 2016. Dr. Aklog also previously served on the Scientific Advisory Boards of numerous leading medical device companies, including
Medtronic, St. Jude Medical, Guidant Cardiac Surgery (now, Maquet Cardiovascular) and Cardiovations (then, a division of Johnson
& Johnson). Dr. Aklog is an inventor on 13 issued patents and over 30 patent applications, including the core patents of Vortex
Medical’s AngioVac system. Prior to entering the medical device industry full-time in 2012, Dr. Aklog was, from 2006 to
2012, Associate Professor of Surgery, Chief of Cardiovascular Surgery and Chair of The Cardiovascular Center at St. Joseph’s
Hospital and Medical Center’s Heart and Lung Institute in Phoenix, Arizona. From 2002 to 2006, Dr. Aklog was Assistant Professor
of Cardiothoracic Surgery, Associate Chief of Cardiac Surgery and Director of Minimally Invasive Cardiac Surgery at Mount Sinai
Medical Center in New York. From 1999 to 2002, Dr. Aklog was Assistant Professor of Surgery at Harvard Medical School, Director
of the Cardiac Surgery Research Laboratory and an attending cardiac surgeon at Brigham and Women’s Hospital in Boston. Dr.
Aklog received his clinical training in general and cardiothoracic surgery at Brigham and Women’s Hospital and Boston Children’s
Hospital, during which he spent two years as the Medtronic Research Fellow at Harvard Medical School’s Cardiac Surgery Research
Laboratory. He was then awarded the American Association of Thoracic Surgery Traveling Fellowship pursuant to which he received
advanced training in heart valve surgery under renowned cardiac surgeons Sir Magdi Yacoub at Harefield Hospital in London and
Professor Alain Carpentier at L’Hopital Broussais in Paris. Dr. Aklog is a co-author on 38 peer-reviewed articles and 10
book chapters. He has served on the Editorial Board of the Journal of Cardiothoracic Surgery since 2006. He is a member
of numerous professional societies and has been elected to the American Association of Thoracic Surgery. He served on the Board
of Directors of the International Society for Minimally Invasive Cardiothoracic Surgery from 2006 to 2009 and as President of
the 21st Century Cardiothoracic Surgery Society in 2011. Dr. Aklog was recognized as one of America’s Top Doctors in the
Castle Connolly Guide from 2002 to 2013. Dr. Aklog received his A.B., magna cum laude , in Physics from Harvard
University, where he was elected to Phi Beta Kappa. Dr. Aklog received his M.D., cum laude , from Harvard Medical School.



We
believe Dr. Aklog is well-qualified to serve on our Board of Directors due to his extensive experience in founding and building
successful medical device companies, his distinguished career as an academic cardiac surgeon, his recognition as a thought leader
and innovator both as a surgeon and a medical device entrepreneur and his widespread relationships in the healthcare and medical
device communities.



1







Item
10. Directors, Executive Officers and Corporate Governance (continued)



Dennis
M. McGrath has served as the Company’s Executive Vice President and Chief Financial Officer since March 2017. Previously,
from 2000 to 2017 Mr. McGrath served in several senior level positions of PhotoMedex, Inc. (Nasdaq: PHMD), a global manufacturer
and distributor of medical device equipment and services, including from 2011 to 2017 as director, President, and Chief Financial
Officer. Prior to PhotoMedex’s reverse merger with Radiancy, Inc in December 2011, he also served as Chief Executive Officer
from 2009 to 2011 and served as Vice President of Finance and Chief Financial Officer from 2000 to 2009. He received honors as
a P.A.C.T. (Philadelphia Alliance for Capital and Technology) finalist for the 2011 Investment Deal of the Year, award winner
for the SmartCEO Magazine 2012 CEO of the Year for Turnaround Company, and finalist for the Ernst & Young 2013 Entrepreneur
of the Year. He has extensive experience in mergers and acquisitions, both domestically and internationally, and particularly
involving public company acquisitions, including Surgical Laser Technologies, Inc, (formerly, Nasdaq: SLTI), ProCyte Corporation
(formerly, Nasdaq: PRCY), LCA Vision, Inc. (formerly, Nasdaq: LCAV) and Think New Ideas, Inc. (formerly, Nasdaq: THNK). Prior
to PhotoMedex, he served in several senior level positions of AnswerThink Consulting Group, Inc. (then, Nasdaq: ANSR, now, The
Hackett Group, Nasdaq: HCKT), a business consulting and technology integration company, including from 1999 to 2000 as Chief Operating
Officer of the Internet Practice, the largest division of AnswerThink Consulting Group, Inc., while concurrently during the merger
of the companies, serving as the acting Chief Financial Officer of Think New Ideas, Inc. (then, Nasdaq: THNK, now, Nasdaq: HCKT),
an interactive marketing services and business solutions company. Mr. McGrath also served from 1996 until 1999 as Chief Financial
Officer, Executive Vice President and director of TriSpan, Inc., an internet commerce solutions and technology consulting company,
which was acquired by AnswerThink Consulting Group, Inc. in 1999. During his tenure at Arthur Andersen & Co., where he began
his career, he became a Certified Public Accountant in 1981 and he holds a B.S., maxima cum laude, in accounting from LaSalle
University. In addition to continuing as a director of PhotoMedex (now First Capital Global, Nasdaq: FCRE), he serves as the audit
chair and a director of several medical device companies, including DarioHealth Corp. (Nasdaq: DRIO), Noninvasive Medical Technologies,
Inc. and Cagent Vascular, LLC, and as an advisor to the board of an orphan drug company, Palvella Therapeutics, LLC. Formerly
from 2007 to 2009, Mr. McGrath served as a director of Embrella Cardiovascular, Inc. (sold to Edwards Lifesciences Corporation,
NYSE: EW). He also serves on the Board of Trustees for Manor College and the Board of Visitors for Taylor University.



Michael
J. Glennon has served as the Company’s Vice Chairman and a Director since October 2014. Mr. Glennon has served as a
co-founding Partner of both PHG and PMI since their respective inceptions in 2007 and 2009 and also serves as Chairman and Chief
Executive Officer of PMI. Mr. Glennon has served as President, Chief Executive Officer and a director of Saphena Medical since
February 2013 and Cruzar Medsystems since July 2013 and as a director of Kaleidoscope Medical since January 2013. Mr. Glennon
was the President and Chief Executive Officer of Vortex Medical from its inception in 2008 until its acquisition in October 2012
by AngioDynamics. From 2005 to 2007, Mr. Glennon was Senior Vice President - Sales and Marketing for Accellent Inc., a market-leading
provider of outsourced precision manufacturing and engineering services to the medical device industry. Accellent was a portfolio
company of DLJ Merchant Banking Partners and was acquired in 2005 by KKR and Bain Capital. From 2004 to 2005, Mr. Glennon was
a Cardiac Rhythm Management District Manager at Medtronic. From 1996 to 2004, Mr. Glennon was a Sales Manager at Guidant including
seven years at Guidant Cardiac Surgery (now, Maquet Cardiovascular). He was instrumental in the launch and rapid growth of VasoView,
the first endoscopic vessel harvesting technology, which became the standard of care in coronary bypass surgery. From 1993 to
1995, Mr. Glennon worked for Origin Medsystems which was acquired by Eli Lilly and subsequently spun out as part of Guidant. Previously,
Mr. Glennon was with Stryker Endoscopy and Storz Instrument Company. Mr. Glennon received his B.S. in Business Administration
from the University of New Hampshire. We believe Mr. Glennon is well-qualified to serve on Board of Directors due to his significant
experience in the marketing and sale of a broad range of medical devices, his expertise in the development and manufacturing of
medical devices, his experience launching, building and running successful medical device companies, and his extensive relationships
in the medical device industry and the broader medical community.



Brian
J . deGuzman, M.D. has served as the Company’s Chief Medical Officer since October 2014 and served as a Director from
October 2014 to January 2015. Dr. deGuzman has served as a co-founding Partner of PHG and PMI since their respective inceptions
in 2007 and 2009. Dr. deGuzman has been President and Chief Executive Officer of Kaleidoscope Medical since its founding in February
2013 and has also served as a Senior Advisor to PMI portfolio companies Saphena Medical since February 2013 and Cruzar Medsystems
since July 2013. Dr. deGuzman served as Chief Medical Officer of Vortex Medical from inception until its sale to AngioDynamics,
for whom he continues to serve as a consultant. Dr. deGuzman has also been a consultant to Biomet and Atricure since 2007, and
on the Revascularization Scientific Advisory Board of Maquet Cardiovascular (formerly Boston Scientific and Guidant Cardiac Surgery)
since 2006. During his surgical career, Dr. deGuzman also served as a consultant to various medical device companies, including
Edward Lifesciences. Prior to moving into the medical device industry full-time in 2012, Dr. deGuzman was Assistant Professor
of Surgery, Associate Chief of Cardiovascular Surgery, and Surgical Director of the Atrial Fibrillation Clinic at St. Joseph’s
Hospital and Medical Center’s Heart and Lung Institute from 2006 to 2012. From 2002 to 2006, Dr. deGuzman was Assistant
Professor of Surgery at Tufts University School of Medicine and an attending cardiac surgeon at the Lahey Clinic Medical Center
in Massachusetts. From 2001 to 2002, Dr. deGuzman was a Clinical Associate of Cardiac Surgery at the Cleveland Clinic. Dr. deGuzman
received his general surgical training at the University of Connecticut/Hartford Hospital, was a Research Fellow at Harvard Medical
School’s Cardiac Surgery Research Laboratory, and received his cardiothoracic surgical training at Brigham and Women’s
Hospital and Boston Children’s Hospital. Dr. deGuzman was recognized as a Top Doctor in Cardiovascular Surgery by Boston
Magazine . Dr. deGuzman received his B.S. in Biology from Boston College and his M.D. from Georgetown University School of
Medicine.



2







Item
10. Directors, Executive Officers and Corporate Governance (continued)



Ronald
M. Sparks has served as a Director since January 2015. Mr. Sparks has more than 37 years of executive experience in the medical
device industry and has launched over 50 products across a wide spectrum of specialties, including orthopedics, endoscopy, wound
management, cardiology, interventional radiology, diagnostic imaging, ophthalmology and otology. From 2007 to October 2013, he
served as a Healthcare Industry Executive at Avista Capital Partners, a private equity firm. Mr. Sparks served as Chairman and
Chief Executive Officer of Navilyst Medical Inc., which was formed by Avista Capital to acquire the fluid management and venous
access business units of Boston Scientific, from its inception in 2008 until its acquisition in May 2012 by AngioDynamics for
$372.0 million. From 2003 to 2007, he served as President, Chief Executive Officer and a director of Accellent, a market-leading
provider of outsourced precision manufacturing and engineering services to the medical device industry. Accellent was a portfolio
company of DLJ Merchant Banking Partners and was acquired in 2005 by KKR and Bain Capital. During his tenure at Accellent, he
was recognized as the Credit Suisse/DLJ Merchant Bank 2005 CEO of The Year. From 1986 to 2003, he served in various leadership
roles at Smith & Nephew as a member of the Group Executive Committee, President of the Endoscopy Division, President of the
Wound Management Division and Vice President of Finance. Earlier in his career, he served in various finance roles at Richards
Medical, Dyonics and Union Carbide Imaging. Mr. Sparks is a fellow of the American Sports Medicine Institute, a Trustee of the
Arthroscopy Association of North America Education Foundation and Honorary Lifetime Member of the International Society of Arthroscopy,
Knee Surgery and Orthopedic Sports Medicine. He has previously served on numerous boards and industry councils, including AdvaMed,
the National Subacute Care Association, the American College of Foot and Ankle Surgeons, the American Council of Orthopedic Surgeons
and the Society of Interventional Radiology. Mr. Sparks received his B.S. in Finance and Accounting from the University of Massachusetts
and attended the INSEAD Advanced Management Program at the European Institute of Business Administration in Fontainebleau, France.



We
believe Mr. Sparks is well-qualified to serve on our Board of Directors due to his executive leadership roles at numerous medical
device companies, his history of success in launching over 50 new medical device products in 16 years, his extensive experience
in acquiring and integrating 14 medical device companies over 15 years, his execution of public financings, and his strong relationships
in the medical community and with private equity and investment banking firms active in the medical device space.



James
L. Cox, M.D. has served as a Director since January 2015. Dr. Cox is a cardiac surgeon, scientific investigator and medical
device entrepreneur who pioneered the field of surgical intervention for cardiac arrhythmias, including the eponymous Cox-Maze
procedure for the treatment of atrial fibrillation. Since January 2017, he has been the Surgical Director of the Center for Heart
Rhythm Disorders at the Bluhm Cardiovascular Institute and the Visiting Professor of Surgery at the Feinberg School of Medicine
at Northwestern University. From 1983 to 1997, Dr. Cox served as Professor of Surgery and Chief of the Division of Cardiothoracic
Surgery at Washington University School of Medicine and Cardiothoracic Surgeon-in-Chief at Barnes Hospital in St. Louis. During
this tenure, he became the first Evarts A. Graham Professor of Surgery and Vice-Chair of the Department of Surgery. From 2005
to December 2016, Dr. Cox was the Emeritus Evarts A. Graham Professor of Surgery at Washington University in St. Louis. Dr. Cox
was also previously Professor and Chairman of the Department of Thoracic and Cardiovascular Surgery at Georgetown University Medical
Center and Associate Professor of Surgery at Duke University Medical Center. Dr. Cox has had a distinguished and highly productive
academic career. He has published 360 peer-reviewed scientific articles and has served on the editorial boards of numerous journals,
including Circulation, the Journal of Thoracic and Cardiovascular Surgery, the Annals of Surgery , and the
Journal of Electrophysiology . His laboratory has received continuous NIH funding for its research on the surgical treatment
of cardiac arrhythmias. Dr. Cox has served in leadership positions at numerous professional organizations. He was the 81st President
of the American Association of Thoracic Surgery and a director of the American Board of Thoracic Surgery. He has been invited
to lecture and perform surgery as a visiting professor at dozens of institutions around the world. He has received numerous awards
and honors for his clinical and scientific work, most notably as one of 30 “Pioneers in Thoracic and Cardiovascular Surgery”
at a ceremony commemorating the 50th anniversary of the specialty. He is the only person to ever receive the Distinguished Scientist
Awards from the Heart Rhythm Society, the Society of Thoracic Surgeons, and the American Society for Thoracic Surgery. Dr. Cox
holds 15 issued patents. He has been instrumental in the founding of six medical device companies, including Epicor Medical, which
was acquired by St. Jude Medical in 2004 for $200 million, and 3F Therapeutics, which was acquired in 2006 by ATS Medical for
$40 million. At such time, he became Medical Director of ATS Medical, which was subsequently acquired by Medtronic in 2010 for
$370 million. Dr. Cox has served on numerous scientific advisory boards, including Medtronic, St. Jude Medical, Atricure and CorMatrix.
He is also the Founder and Chairman of the Board of Directors of the World Heart Foundation, a not-for-profit organization devoted
to improving access to cardiac surgery, which is active in over 75 developing countries around the world. Dr. Cox received his
general and cardiothoracic surgical training at Duke University School of Medicine, during which time he spent two years in the
U.S. Army Medical Corps. Dr. Cox received his M.D. from the University of Tennessee, where he received the Alpha Omega Alpha Distinguished
Graduate Award as the outstanding student in his class.



We
believe Dr. Cox is well-qualified to serve on our Board of Directors due to his distinguished career as a world-renowned cardiac
surgeon and scientific investigator, his recognition as a thought leader and innovator both as a surgeon and medical device entrepreneur,
his extensive experience in the medical device industry and his widespread relationships in all segments of the healthcare community.



3







Item
10. Directors, Executive Officers and Corporate Governance (continued)



David
S. Battleman, M.D. has served as a Director since August 2017. Dr. Battleman is a seasoned healthcare executive with over
15 years of experience, spanning academia, industry and management consulting. Prior to establishing his own consulting firm,
TrueNorth Lifesciences, in August 2012, Dr. Battleman served as a senior principal in the pharmaceutical/medical device consulting
practice within IMS Health (currently QuintileIMS, NYSE: Q), a Fortune 500 company providing data and consulting services to the
pharmaceutical and medical industries. Prior to joining IMS, Dr. Battleman served as a management consultant in the healthcare
practice of Bain & Company, a leading strategy and management consulting firm. Within industry, Dr. Battleman served for several
years as a director for Pfizer Pharmaceuticals (NYSE: PFE) where he was responsible for developing value-based product strategy
across Pfizer’s cardiovascular portfolio, ranging from early-stage to marketed products. And within academia, Dr. Battleman
was an assistant professor of public health and internal medicine at Cornell University’s Weill Cornell Medical College.
There, Dr. Battleman’s research focused primarily on the areas of health economics and technology assessment and he has
published both original research and expert reviews in these areas. Dr. Battleman holds an M.D. from Weill Cornell Medical College,
an M.B.A. from the University of Pennsylvania’s Wharton School of Business, and an M.Sc. in clinical epidemiology &
quantitative methods from the Harvard School of Public Health. Dr. Battleman also holds his Series 63 & 82 licenses and is
a FINRA registered representative with Pickwick Capital Partners.



We
believe Dr. Battleman is well-qualified to serve on our Board of Directors due to his extensive experience as medical device consultant
with Fortune 500 companies, his integration of medicine, science, and business education and training and the practical application
of that training, his background in developing value-based strategy within the pharmaceutical space and his strong relationships
in the medical community and with private equity and investment banking active in the medical device space.



David
Weild IV has served as a Director since February 2015. He is the founding Chairman and Chief Executive Officer of Weild &
Co., Inc., an innovative investment bank serving the growth economy that was established in late 2013, and as Manager of its broker-dealer
since 2003, which is now a wholly-owned subsidiary of Weild & Co. Mr. Weild also served as Senior Advisor - Capital Markets
to Grant Thornton LLP, a leading public accounting firm, from 2008 to 2013. Previously, Mr. Weild served as Vice Chairman, Executive
Vice President and Head of Listed Companies, and a member of the Executive Committee of The Nasdaq Stock Market from 2000 to 2003.
Prior to joining Nasdaq, from 1987 to 2000, Mr. Weild held positions of increasing responsibility at Prudential Securities Inc.,
including Vice President and Equity Syndicate Manager, Managing Director and Head of the Global Equity Transactions Group, Managing
Director and Head of Corporate Finance and President of PrudentialFinancial.com, including PrudentialSecurities.com. Mr. Weild
is a recognized expert on capital formation and capital markets structure and has co-authored a number of definitive white papers,
studies and articles which have been cited by legislators, regulators, academics, the IPO Task Force, the Equity Capital Formation
Task Force and the White House Jobs Council and which are widely regarded as having served as catalysts for reforms and new legislation,
including the JOBS Act. Mr. Weild has spoken at the G-20 and testified before Congress and the SEC. Mr. Weild has also presented
to the Organization of Economic Cooperation and Development (OECD) about the role of stock market reforms in driving economic
growth. Mr. Weild received his B.A. from Wesleyan University and his M.B.A. from New York University Stern School of Business
and also studied at the Sorbonne and on exchange at the Ecoles des Hautes Etudes Commerciales (HEC Paris) and the Stockholm School
of Economics.



We
believe Mr. Weild is well-qualified to serve on our Board of Directors due to his extensive experience in corporate finance, including
more than 1,000 equity offerings during his career, his deep knowledge and recognized leadership in capital formation and capital
markets structure and his widespread relationships in the financial community.



4







Item
10. Directors, Executive Officers and Corporate Governance (continued)



Classification
of Board



Our
Board of Directors is divided into three classes with only one class of directors being elected in each year and each class serving
a three-year term. The term of office of the first class of directors, consisting of Mr. Sparks and Dr. Battleman will expire
at our annual meeting in 2020. The term of office of the second class of directors, consisting of Dr. Cox and Mr. Weild, will
expire at our annual meeting in 2018. The term of office of the third class of directors, consisting of Dr. Aklog
and Mr. Glennon, will expire at our annual meeting in 2019.



Family
Relationships



There
are no family relationships among any of our directors or executive officers.



Conflicts
of Interest



In
order to minimize potential conflicts of interest which may arise from the corporate affiliations described below, each of Dr.
Aklog, Mr. Glennon and Dr. deGuzman has contractually agreed, pursuant to a written agreement with us, until such time as he ceases
to be an officer, to present to us for our consideration, prior to presentation to any other entity, any suitable business opportunity
which may reasonably be required to be presented to us, subject to the existing pre-existing fiduciary obligations set forth below.



As
an affiliate of Saphena Medical, Kaleidoscope Medical and Cruzar Medsystems, Mr. Glennon may have a fiduciary responsibility to
present certain business opportunities to such entities within their specific lines of business. Saphena Medical’s line
of business is endoscopic vessel harvesting, Kaleidoscope Medical’s is inferior vena caval filters and Cruzar Medsystems’
is peripheral vascular intervention for chronic total occlusions. Accordingly, it is possible Mr. Glennon may present opportunities
to such entities prior to presenting them to us.



As
an affiliate of Kaleidoscope Medical, Dr. deGuzman may have a fiduciary responsibility to present certain business opportunities
to this entity within its line of business, namely inferior vena caval filters. Accordingly, it is possible he may present opportunities
to Kaleidoscope Medical prior to presenting them to us.



Although
Drs. Aklog, deGuzman and Mr. Glennon are affiliates of PHG and PMI, there is no potential conflict with them presenting corporate
opportunities to these entities over us. PHG is a holding company which holds their stakes in existing entities but does not invest
in new companies. Its operating agreement explicitly states that they do not have an obligation to present corporate opportunities
to PHG. Similarly, PMI is currently an intellectual property holding company without any ongoing business. Accordingly, they have
no fiduciary or contractual obligations to present corporate opportunities or assign intellectual property to either entity.



5







Item
10. Directors, Executive Officers and Corporate Governance (continued)



Audit
Committee



Effective
January 29, 2016, we established an audit committee of the Board of Directors, which consists of Messrs. Weild, Sparks, and Dr.
Battleman, each of whom is an independent director under Nasdaq’s listing standards. The audit committee’s duties,
which are specified in our Audit Committee Charter, include, but are not limited to:



| | ● | reviewing
    and discussing with management and the independent auditor the annual audited financial statements, and recommending to the
    board whether the audited financial statements should be included in our Form 10-K;                                                              
| | - | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
| |   |                                                                                                                                                                                                                                                                                                
| | ● | discussing
    with management and the independent auditor significant financial reporting issues and judgments made in connection with the
    preparation of our financial statements;                                                                                                       
| |   |                                                                                                                                                                                                                                                                                                
| | ● | discussing
    with management major risk assessment and risk management policies;                                                                                                                                                                                                             
| |   |                                                                                                                                                                                                                                                                                                
| | ● | monitoring
    the independence of the independent auditor;                                                                                                                                                                                                                                    
| |   |                                                                                                                                                                                                                                                                                                
| | ● | verifying
    the rotation of the lead (or coordinating) audit partner having primary responsibility for the audit and the audit partner
    responsible for reviewing the audit as required by law;                                                                                           
| |   |                                                                                                                                                                                                                                                                                                
| | ● | reviewing
    and approving all related-party transactions;                                                                                                                                                                                                                                    
| |   |                                                                                                                                                                                                                                                                                                
| | ● | inquiring
    and discussing with management our compliance with applicable laws and regulations;                                                                                                                                                                                              
| |   |                                                                                                                                                                                                                                                                                                
| | ● | pre-approving
    all audit services and permitted non-audit services to be performed by our independent auditor, including the fees and terms
    of the services to be performed;                                                                                                            
| |   |                                                                                                                                                                                                                                                                                                
| | ● | appointing
    or replacing the independent auditor;                                                                                                                                                                                                                                           
| |   |                                                                                                                                                                                                                                                                                                
| | ● | determining
    the compensation and oversight of the work of the independent auditor (including resolution of disagreements between management
    and the independent auditor regarding financial reporting) for the purpose of preparing or issuing an audit report or related
    work; and
| |   |                                                                                                                                                                                                                                                                                                
| | ● | establishing
    procedures for the receipt, retention and treatment of complaints received by us regarding accounting, internal accounting
    controls or reports which raise material issues regarding our financial statements or accounting policies.                                     



Financial
Experts on Audit Committee



The
audit committee will at all times be composed exclusively of “independent directors” who are “financially
literate” as defined under Nasdaq listing standards. Nasdaq listing standards define “financially literate”
as being able to read and understand fundamental financial statements, including a company’s balance sheet, income statement,
and statement of cash flows.



In
addition, we must certify to Nasdaq the committee has, and will continue to have, at least one member who has past employment
experience in finance or accounting, requisite professional certification in accounting, or other comparable experience or background
that results in the individual’s financial sophistication. The Board of Directors has determined Dr. Battleman, and Messrs.
Weild and Sparks each qualify as an “audit committee financial expert,” as defined under rules and regulations
of the SEC, andas financially sophisticated, under
the Nasdaq listing standards.



6







Item
10. Directors, Executive Officers and Corporate Governance (continued)



Nominating
Committee



Effective
January 29, 2016, we established a nominating committee of the Board of Directors, which consists of Drs. Battleman and Cox and
Mr. Sparks, each of whom is an independent director under Nasdaq’s listing standards. The nominating committee is responsible
for overseeing the selection of persons to be nominated to serve on our Board of Directors. The nominating committee considers
persons identified by its members, management, stockholders, investment bankers and others.



Guidelines
for Selecting Director Nominees



The
guidelines for selecting nominees, which are specified in the Nominating Committee Charter, generally provide that persons to
be nominated:



| | ● | should
    have demonstrated notable or significant achievements in business, education or public service;                                                                                                                          
| | - | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
| |   |                                                                                                                                                                                                                                     
| | ● | should
    possess the requisite intelligence, education and experience to make a significant contribution to the Board of Directors
    and bring a range of skills, diverse perspectives and backgrounds to its deliberations; and
| |   |                                                                                                                                                                                                                                     
| | ● | should
    have the highest ethical standards, a strong sense of professionalism and intense dedication to serving the interests of the
    stockholders.                                                                           



The
Nominating Committee will consider a number of qualifications relating to management and leadership experience, background and
integrity and professionalism in evaluating a person’s candidacy for membership on the Board of Directors. The nominating
committee may require certain skills or attributes, such as financial or accounting experience, to meet specific board needs that
arise from time to time and will also consider the overall experience and makeup of its members to obtain a broad and diverse
mix of board members. Though the Nominating Committee does not have specific guidelines on diversity, it is one of many criteria
considered by the Nominating Committee when evaluating candidates. The nominating committee does not distinguish among nominees
recommended by stockholders and other persons.



Pursuant
to the Note and Securities Purchase Agreement (the “NSPA”) dated June 30, 2017 between the Company and Scopia
Holdings LLC (the “Lender”), for so long as the Lender holds at least 50% of the aggregate principal balance
of all outstanding promissory notes issued pursuant to the NSPA, the Lender shall have the ability to nominate (and remove) one
member of the Board. The Lender has designated David S. Battleman, M.D., as its nominee to serve as a director.



There
have be no materials changes to the procedures by which security holders may recommend nominees to our Board of Directors.



Compensation
Committee



Effective
January 29, 2016, we established a compensation committee of the Board of Directors, which consists of Drs. Battleman and Cox
and Mr. Weild, each of whom is an independent director under Nasdaq’s listing standards. The compensation committee’s
duties, which are specified in our Compensation Committee Charter, include, but are not limited to:



| | ● | reviewing
    and approving on an annual basis the corporate goals and objectives relevant to our Chief Executive Officer’s compensation,
    evaluating our Chief Executive Officer’s performance in light of such goals and objectives and determining and approving
    the remuneration (if any) of our Chief Executive Officer’s based on such evaluation;
| | - | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
| |   |                                                                                                                                                                                                                                                                                                                                                                
| | ● | reviewing
    and approving the compensation of all of our other executive officers (including through our management services agreements
    described below);                                                                                                                                                                                                
| |   |                                                                                                                                                                                                                                                                                                                                                                
| | ● | reviewing
    our executive compensation policies and plans;                                                                                                                                                                                                                                                                                                   
| |   |                                                                                                                                                                                                                                                                                                                                                                
| | ● | implementing
    and administering our incentive compensation equity-based remuneration plans;                                                                                                                                                                                                                                                                 
| |   |                                                                                                                                                                                                                                                                                                                                                                
| | ● | assisting
    management in complying with our proxy statement and annual report disclosure requirements;                                                                                                                                                                                                                                                      
| |   |                                                                                                                                                                                                                                                                                                                                                                
| | ● | approving
    all special perquisites, special cash payments and other special compensation and benefit arrangements for our executive officers
    and employees;                                                                                                                                                                                             
| |   |                                                                                                                                                                                                                                                                                                                                                                
| | ● | if
    required, producing a report on executive compensation to be included in our annual proxy statement; and                                                                                                                                                                                                                                                
| |   |                                                                                                                                                                                                                                                                                                                                                                
| | ● | reviewing,
    evaluating and recommending changes, if appropriate, to the remuneration for directors.                                                                                                                                                                                                                                                         



7







Item
10. Directors, Executive Officers and Corporate Governance (continued)



Code
of Ethics



In
April 2015, we adopted a code of ethics that applies to all of our respective executive officers, directors and employees. The
code of ethics codifies the business and ethical principles that govern all aspects of our business. This code of ethics is posted
on our corporate website at www.pavmed.com. In addition, we intend to post on our website disclosures that are required by law
concerning any amendments to, or waivers from, any provision of our code of ethics.



Section
16(a) Beneficial Ownership Reporting Compliance



Section
16(a) of the Exchange Act requires our directors and certain officers and holders of more than 10% of our common stock to file
with the SEC initial reports of ownership of our common stock and other equity securities on Form 3 and reports of changes in
such ownership on a Form 4 or Form 5.



Such
Section 16 reporting persons are required by SEC regulations to furnish us with copies of all Section 16(a) forms they file. To
our knowledge, during the fiscal years ended December 31, 2017 all reports required to be filed pursuant to Section 16(a) were
filed on a timely basis, except for:



|(i)   | David
    S. Battleman, M.D., filed a Form 4 on August 11, 2017 which included one transaction not timely reported (the acquisition
    of a stock option to purchase 40,000 shares of common stock dated August 2, 2017);                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
|----- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|      |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
|(ii)  | Lishan
    Aklog, M.D., (a) filed a Form 4 on August 25, 2017, which included two transactions not timely reported (the acquisition of
    7,500 and 1,500 shares of common stock on August 21, 2017 and August 22, 2017, respectively), (b) filed a Form 4 on September
    5, 2017, which included four transactions not timely reported (the acquisition of 1,412 shares of common stock and 1,200 warrants
    on August 29, 2017 and the acquisition of 300 shares of common stock and 200 Series W Warrants on August 30, 2017), and, (c)
    filed a Form 4 on September 21, 2017, which included one transaction not timely reported (the acquisition of 2,600 shares
    of common stock on September 15, 2017);                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
|      |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
|(iii) | in
    connection with the distribution by HCFP/Capital Partners III LLC to its members, on a pro rata basis, of 5,646,562 shares
    of common stock, and the immediate contribution by each of Michael J. Glennon and Brian J. deGuzman, M.D., to Pavilion Venture
    Partners LLC of the such shares each received in such distribution, all of which occurred on December 21, 2017: (a) Mr. Glennon
    filed a Form 4 on December 29, 2017, which included two transactions not timely reported (the acquisition of shares by him
    in the distribution from HCFP/Capital Partners III LLC, and the disposition of such shares by him in the contribution to Pavilion
    Venture Partners LLC); (b) Brian J deGuzman, M.D., filed a Form 4 on January 3, 2018, which included two transactions not
    timely reported (the acquisition of shares by him in the distribution from HCFP/Capital Partners III LLC, and the disposition
    of such shares by him in the contribution to Pavilion Venture Partners LLC); (c) HCFP/Capital Partners III LLC filed a Form
    5 on February 14, 2018, which included one transaction not timely reported (the disposition of shares in the aforementioned
    distribution); and, (d) Pavilion Venture Partners LLC filed a Form 5 on February 14, 2018, which included one transaction
    not timely reported (the aforementioned acquisition of shares in the contribution).







Board
Meetings



During
the fiscal year ended December 31, 2017, our Board of Directors held eleven meetings and acted by unanimous written consent three
times. All of our directors attended 75% or more of the aggregate number of meetings of the board and meetings of committees on
which they served. We strongly encourage our directors to attend our annual meetings of shareholders.



8







Item
11. Executive and Director Compensation



This
section describes the material elements of compensation awarded to, earned by, or paid to, each of our named executive officers,
and the qualitative information regarding the manner and context in which compensation is awarded to and earned by our named executive
officers, and is intended to place in perspective the data presented in the tables and narrative presented.



Summary
Compensation Table - Named Executive Officers



The
following table sets forth summarized compensation awarded to, earned by or paid to our named executive officers, for 2017 and
2016.



|                                  |  |      |      |  |        |   |         | Equity         |  |   |         |     |  |              |         |        |       |  
|--------------------------------- |  | ---- | ---- |  | ------ | - | ------- | -------------- |  | - | ------- | --- |  | ------------ | ------- | ------ | ----- | -
|                                  |  |      |      |  |        |   |         | Incentive      |  |   |         |     |  |              |         |        |       |  
|                                  |  |      |      |  |        |   |         | Awards         |  |   |         |     |  | All          |         |        |       |  
|Named
    Executive Officer       |  |      |      |  |        |   |         | Estimated      |  |   |         |     |  | Other        |         |        |       |  
|/Principal
    Position           |  | Year |      |  | Salary |   |         | Fair
    Value |  |   | Bonus   |     |  | Compensation |         |        | Total |  
|Lishan
    Aklog, M.D.            |  |      | 2017 |  |        | $ | 296,700 | (1)            |  | $ | —       | (6) |  | $            | 147,500 | (7)    |       | $
|Chairman
    - Board of Directors |  |      | 2016 |  |        | $ | 295,000 | (1)            |  | $ | 367,779 | (6) |  | $            | 124,583 | (2)(7) |       | $
|&
    Chief Executive Officer     |  |      |      |  |        |   |         |                |  |   |         |     |  |              |         |        |       |  
|                                  |  |      |      |  |        |   |         |                |  |   |         |     |  |              |         |        |       |  
|Dennis
    M. McGrath             |  |      | 2017 |  |        | $ | 217,421 | (4)            |  | $ | 725,000 | (6) |  | $            | 118,750 | (7)    |       | $
|Executive
    Vice President      |  |      | 2016 |  |        | $ | —       |                |  | $ | —       |     |  | $            | —       |        |       | $
|Chief
    Financial Officer       |  |      |      |  |        |   |         |                |  |   |         |     |  |              |         |        |       |  
|Corporate
    Secretary           |  |      |      |  |        |   |         |                |  |   |         |     |  |              |         |        |       |  
|                                  |  |      |      |  |        |   |         |                |  |   |         |     |  |              |         |        |       |  
|Michael
    J. Glennon            |  |      | 2017 |  |        | $ | —       |                |  | $ | —       | (6) |  | $            | —       |        |       | $
|Vice
    Chairman                 |  |      | 2016 |  |        | $ | —       |                |  | $ | 367,779 | (6) |  | $            | —       |        |       | $
|Board
    of Directors Member     |  |      |      |  |        |   |         |                |  |   |         |     |  |              |         |        |       |  
|                                  |  |      |      |  |        |   |         |                |  |   |         |     |  |              |         |        |       |  
|Brian
    J. deGuzman             |  |      | 2017 |  |        | $ | 285,000 | (5)            |  | $ | —       | (6) |  | $            | 114,000 | (7)    |       | $
|Chief
    Medical Officer         |  |      | 2016 |  |        | $ | 192,500 | (5)            |  | $ | 367,779 | (6) |  | $            | —       | (7)    |       | $



|(1) | Effective
    November 1, 2014, we entered into a five year employment agreement with Dr. Lishan Aklog, M.D. to serve as our Chief Executive
    Officer, with an annual base salary of $240,000 through October 31, 2015, and $295,000 per year effective November 1, 2015.
    Additionally, effective as of January 1, 2016, Dr. Aklog’s employment agreement provides for a guaranteed annual bonus
    equal to 50% of base salary, beginning on January 1 of each year, as well as also being eligible to earn additional discretionary
    annual performance bonuses upon meeting certain objectives as determined by the Board of Directors.                                                                                                                                                                                                                                                                                                                                                                                                        
|--- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
|    | Notwithstanding,
    under the terms of the NSPA with the Lender, including the Senior Secured Note issued thereunder, effective with the
    first bi-monthly payroll in July 2017, the CEO agreed to payment of a reduced salary of $4,200 per month, with the payment
    of such earned but unpaid salary to occur on the earlier of (a) the date of FDA 510(k) clearance for the PortIOTM product
    is obtained or (b) the date the aggregate remaining unpaid principal balance of the Senior Secured Note is repaid-in-full.
    Subsequently, the Lender irrevocably waived compliance with this provision by the Company and Dr. Aklog on a prospective
    basis commencing February 1, 2018, wherein, the earned but unpaid CEO salary for the period July 1, 2017 to January
    31, 2018 may only be paid upon the Senior Secured Note first being repaid-in-full. See our consolidated financial statements
    Note 12, Note and Securities Purchase Agreement, Senior Secured Note, and Series S Warrants, for a discussion of the
    NSPA.
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
|(2) | As
    agreed to by Dr. Aklog, the $124,583 guaranteed bonus otherwise payable on January 1, 2016, was only to be paid upon the successful
    consummation of our initial public offering, which occurred on April 28, 2016, resulting in such payment on May 10, 2016.
    Further, effective December 31, 2016, Dr. Aklog permanently waived his right to receive the guaranteed bonus payment for 2016.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
|(3) | A
    payment totaling $240,000, including $200,000 applicable to 2015 and $40,000 applicable to 2016, was only to be paid to Dr.
    Aklog upon the successful consummation of our initial public offering, which occurred on April 28, 2016, resulting in such
    payment on May 10, 2016.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
|(4) | On
    March 20, 2017, we entered into a two year employment agreement with Dennis M. McGrath, to serve as our Executive Vice President
    and Chief Financial Officer (“CFO”), with an annual base salary of $285,000, a discretionary annual performance
    bonus with a target of 50% of the then current annual base salary, based upon his performance and the Company’s performance
    over the preceding year, as determined by the compensation committee of the Board of Directors, and, for the period May
    1, 2017 to March 31, 2018, a housing and travel allowance of up to $2,250 per month.                                                                                                                                                                                                                                                                                                                                                                                                                                             



9







Item
11. Executive and Director Compensation (continued)



Summary
Compensation Table (continued)



|(5) | Effective
    July 1, 2016, we entered into a five-year employment agreement with Dr. Brian J. deGuzman, M.D. to serve as our Chief Medical
    Officer with a base annual salary of $285,000; an initial bonus of $50,000 for services provided before the employment
    agreement’s effective date, and, a discretionary annual performance bonus with a target of 40% of the then current annual
    base salary, upon meeting certain objectives as determined by the compensation committee of the Board of Directors.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
|--- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
|(6) | The
    amounts reported under “Equity Incentive Awards Estimated Fair Value” is the estimated grant date fair value of
    such stock options granted during the respective year, as presented in the named executive officers “Stock Option
    Grants” table herein below, with such amount as determined under the provisions of Financial Accounting Standards
    Board (FASB) Accounting Standard Codification (ASC) Topic 718 (ASC 718), with respect to accounting for stock-based compensation
    expense. Such estimated fair value amounts do not necessarily correspond to the potential actual value realized of such stock
    options. The assumptions made in computing the estimated fair value of such stock options are discussed in our consolidated
    financial statements Note 2, Summary of Significant Accounting Policies - Stock Based Compensation, and Note 10, Stock Based
    Compensation, as included in our Annual Report on Form 10-K for the year ended December 31, 2017, previously filed
    with the SEC on March 14, 2018.
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
|(7) | On
    February 14, 2018, the compensation committee of the board of directors authorized the payment of Dr. Aklog’s guaranteed
    bonus for 2017 and the payment of a discretionary bonus to each of Mr. McGrath and Dr. deGuzman, with such amounts consistent
    with their respective employment agreements, each as described herein above.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
|    | As
    determined by our board of directors, no discretionary bonus payments were authorized for 2016, and as noted above, effective
    December 31, 2016, Dr. Aklog permanently waived his right to receive the guaranteed bonus payment for 2016.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
|(8) | Effective
    June 30, 2017, we mutually agreed with Mr. Glennon to terminate the consulting agreement between us and Mr. Glennon previously
    effective October 1, 2016, under which Mr. Glennon agreed to provide us with services and advice relating to the successful
    development and commercialization of medical device products. Effective as of December 31, 2016, Mr. Glennon waived his right
    to compensation under the consulting agreement for the year ended December 31, 2016, and, effective as of March 31, 2017,
    Mr. Glennon further waived his right to compensation under the consulting agreement for the period January 1, 2017 through
    June 30, 2017.                                                                                                                                                                                                                                                                                                                                                                        





10







Item
11. Executive and Director Compensation (continued)



Outstanding
Equity Incentive Compensation at Fiscal Year-End



The
outstanding stock options held by our named executive officers at December 31, 2017, as follows:



|                            |  | Stock
    Option Grants |        
|--------------------------- |  | ----------------------- | -------
|                            |  | Number                  |        
|                            |  | of                      |        
|                            |  | Securities              |        
|                            |  | Underlying              |        
|                            |  | Stock                   |        
|                            |  | Options                 |        
|Name                        |  | Exercisable             |        
|Lishan
    Aklog, M.D.      |  |                         | 154,848
|Dennis
    M. McGrath       |  |                         | 62,503 
|Michael
    J. Glennon      |  |                         | 154,848
|Brian
    J. deGuzman, M.D. |  |                         | 154,848



Upon
his employment on March 20, 2017, Mr. McGrath was granted a stock option to purchase 250,000 shares of our common stock at an
exercise price of $5.95 per share. There were no equity incentive compensation awards granted in 2017 to Dr. Aklog, Mr. Glennon,
or Dr. deGuzman. On April 28, 2016, upon the consummation of our initial public offering, each of Dr. Aklog, Mr. Glennon, and
Dr. deGuzman, were granted a stock option to purchase 278,726 shares of our common stock at $5.00 per share.



Subsequent
to December 31, 2017, on February 14, 2018, the compensation committee of the board of directors authorized the grants of a stock
option to purchase 195,108 shares of our common stock to each of Dr. Aklog and Mr. McGrath, and 100,000 shares of our common stock
to each of Mr. Glennon and Dr. deGuzman, with such stock options having a February 14, 2018 grant date, an exercise price
of $2.01 per share, and vesting ratably on a quarterly basis over a three year period commencing March 31, 2018 and ending
December 31, 2020.



Although
we do not have a formal policy with respect to the grant of equity incentive compensation awards to our named executive officers,
or any formal equity ownership guidelines applicable to them, we believe granting equity incentive compensation to our
named executives provide a strong link to our long-term performance, creates an ownership culture, and aligns the
interests of our named executive officers with our stockholders. Accordingly, our board of directors periodically reviews the
equity incentive compensation of our named executive officers and, from time to time, may grant equity incentive compensation
to them in the form of stock options and /or other equity awards.



401(k)
Retirement Plan



We
maintain a 401(k) retirement plan intended to be a tax-qualified defined contribution plan under Section 401(k) of the Internal
Revenue Code. In general, all of our employees are eligible to participate, beginning on the first day of the month following
commencement of their employment. The 401(k) plan includes a salary deferral arrangement pursuant to which participants may elect
to reduce their current compensation by up to the statutorily prescribed limit, equal to $18,000 in 2017 and 2016, and have the
amount of the reduction contributed to the 401(k) plan. Participants who are at least 50 years old also can make “catchup”
contributions, which in 2017 and 2016 may be up to an additional $6,000 above the statutory limit. The Company has the option
to make discretionary matching contributions. During the years ended December 31, 2017 and 2016, the Company did not elect to
make any discretionary matching contributions to the 401(k) plan.



11









Item
11. Executive and Director Compensation (continued)



Employment
Agreements - Names Executive Officers



Lishan
Aklog, M.D. - Chief Executive Officer



Effective
November 1, 2014, we entered into a five year employment agreement with Dr. Lishan Aklog, M.D. to serve as our Chief Executive
Officer, initially with an annual base salary of $240,000 through October 31, 2015, and then $295,000 per year effective November
1, 2015. Additionally, effective as of January 1, 2016, Dr. Aklog’s employment agreement provides for a guaranteed annual
bonus equal to 50% of base salary, beginning on January 1 of each year, as well as also being eligible to earn additional discretionary
annual performance bonuses upon meeting certain objectives as determined by the Board of Directors.



Notwithstanding,
under the terms of the NSPA with the Lender, including the Senior Secured Note issued thereunder effective with
the first bi-monthly payroll in July 2017, Dr. Aklog agreed to payment of a reduced salary of $4,200 per month, with the
payment of such earned but unpaid salary to occur on the earlier of (a) the date of FDA 510(k) clearance for the PortIOTM
Product is obtained or (b) the date the aggregate remaining unpaid principal balance of the Senior Secured Note is repaid-in-full.
Subsequently, the Lender irrevocably waived compliance with this provision by the Company and Dr. Aklog on a prospective
basis commencing February 1, 2018, wherein, the earned but unpaid CEO salary for the period July 1, 2017 to January 31,
2018 may only be paid upon the Senior Secured Note first being repaid-in-full. See our consolidated financial statements Note
12, Note and Securities Purchase Agreement, Senior Secured Note, and Series S Warrants, for a discussion of the Note and
Security Purchase Agreement with Scopia Holdings LLC.



As
presented in the “Summary Compensation Table” herein above: (i) on February 14, 2018, the compensation committee of
the board of directors authorized the payment of Dr. Aklog’s $147,500 guaranteed bonus for 2017, with such bonus payment
made on March 9, 2018; (ii) effective December 31, 2016, Dr. Aklog permanently waived his right to receive the guaranteed bonus
payment for 2016; (iii) as agreed to by Dr. Aklog, the $124,583 guaranteed bonus otherwise payable on January 1, 2016, was only
to be paid upon the successful consummation of our initial public offering, which occurred on April 28, 2016, resulting in such
payment on May 10, 2016; (iv) a payment totaling $240,000, including $200,000 applicable to 2015 and $40,000 applicable to 2014,
was only to be paid to Dr. Aklog upon the successful consummation of our initial public offering, which occurred on April 28,
2016, resulting in such payment on May 10, 2016.



On
February 14, 2018, the compensation committee of the board of directors authorized the grant to Dr. Aklog of a stock option
to purchase 195,108 shares of our common stock, having a February 14, 2018 grant date, an exercise price of $2.01 per share,
and vesting ratably on a quarterly basis over a three year period commencing March 31, 2018 and ending December 31, 2020.
There were no equity incentive compensation awards granted in 2017 to Dr. Aklog. On April 28, 2016, upon the consummation of
our initial public offering, Dr. Aklog was granted a stock option to purchase 278,726 shares of our common stock at $5.00 per
share, vesting 3/36 on July 28, 2016 and 1/36 on each successive month thereafter from Aug 28, 2016 to April 28,
2019.



Upon
termination of employment, unless terminated by us without “cause” or by Dr. Aklog with “good reason”
(as such terms are defined in the employment agreement), Dr. Aklog will be entitled only to his base salary through the date of
termination, valid expense reimbursements and unused vacation pay. If terminated by us without “cause” or by Dr. Aklog
with “good reason,” he is entitled to be paid his base salary through the end of the employment agreement remaining
term at 150% of base salary, valid expense reimbursements and accrued but unused vacation pay.



Dr.
Aklog’s employment agreement contains provisions for the protection of our intellectual property and contains non-compete
restrictions in the event of his termination other than by us without “cause” or by Dr. Aklog with “good reason”
(generally imposing restrictions on (i) employment or consultation with competing companies or customers, (ii) recruiting or hiring
employees for a competing company and (iii) soliciting or accepting business from our customers for a period of six months following
termination). Pursuant to the agreement, Dr. Aklog may serve as a consultant to, or on boards of directors of, or in any other
capacity to other companies provided they will not interfere with the performance of his duties to us.



12







Item
11. Executive and Director Compensation (continued)



Employment
Agreements - Names Executive Officers - (continued)



Dennis
M. McGrath - Executive Vice President - Chief Financial Officer



On
March 20, 2017, we entered into a two year employment agreement with Dennis M. McGrath, to serve as our Executive Vice President
and Chief Financial Officer, with an annual base salary of $285,000, a discretionary annual performance bonus with a target of
50% of the then current annual base salary, based upon his performance and the Company’s performance over the preceding
year, as determined by the compensation committee of the Board of Directors, and, for the period May 1, 2017 to March 31, 2018,
a housing and travel allowance of up to $2,250 per month.



As
presented in the “Summary Compensation Table” herein above, on February 14, 2018, the compensation committee of the
board of directors authorized the payment of a $118,750 discretionary bonus to Mr. McGrath, with such bonus payment made on March
9, 2018.



On
February 14, 2018, the compensation committee of the board of directors authorized the grant to Mr. McGrath of a stock option
to purchase 195,108 shares of our common stock, having a February 14, 2018 grant date, an exercise price of $2.01 per share, and
vesting ratably on a quarterly basis over a three year period commencing March 31, 2018 and ending on December 31, 2020.
Upon his employment on March 20, 2017, Mr. McGrath was granted a stock option to purchase 250,000 shares of our common stock at
an exercise price of $5.95 per share and vesting ratably on a quarterly basis over a three year period commencing June 30, 2017
to March 31, 2020.



If
his employment is terminated by us without “cause” or by him with “good reason” (as such terms are defined
in the employment agreement), Mr. McGrath is entitled to receive his base salary through the date of termination and for a period
of six months thereafter (or until the end of the term, if earlier), a pro rata portion of any annual bonus to which he would
have been entitled, all valid expense reimbursements, health insurance coverage for six months if he elects continued coverage
pursuant to the Consolidated Omnibus Budget Reconciliation Act of 1985, as amended, and all accrued but unused vacation pay. If
his employment is terminated due to his death or disability, he will be entitled to the same amounts, except he will only be entitled
to his base salary through the date of termination and he will not be entitled to continued health insurance coverage. If his
employment is terminated by us with “cause” or by him without “good reason,” Mr. McGrath will be entitled
only to his base salary through the date of termination, valid expense reimbursements and certain accrued but unused vacation
pay.



Mr.
McGrath’s employment agreement contains provisions protecting our intellectual property and contains provisions restricting
his ability to compete with us during his employment and for a period of two years thereafter. The non-compete provisions generally
impose restrictions on (i) employment or consultation with competing companies or customers, (ii) recruiting or hiring employees
for a competing company and (iii) soliciting or accepting business from our customers for a period of six months following termination,
except the restrictions in clause (i) will not apply if he is terminated without “cause” or resigns for “good
reason.” Mr. McGrath may serve as a consultant to, or on boards of directors of other companies provided they will not interfere
with the performance of his duties to us.



13







Item
11. Executive and Director Compensation (continued)



Employment
Agreements - Names Executive Officers - (continued)



Brian
J. deGuzman M.D. - Chief Medical Officer



Effective
July 1, 2016, we entered into a five-year employment agreement with Dr. Brian J. deGuzman, M.D. to serve as our Chief Medical
Officer with a base annual salary of $285,000; an initial bonus of $50,000 for services provided before the employment
agreement’s effective date, and, a discretionary annual performance bonus with a target of 40% of the then current annual
base salary, upon meeting certain objectives as determined by the compensation committee of the board of directors.



As
presented in the “Summary Compensation Table” herein above, on February 14, 2018, the compensation committee of the
board of directors authorized the payment of a $114,000 discretionary bonus to Dr. deGuzman, with such bonus payment made on March
9, 2018.



On
February 14, 2018, the compensation committee of the board of directors authorized the grant to Dr. deGuzman of a stock
option to purchase 100,000 shares of our common stock, having a February 14, 2018 grant date, an exercise price of
$2.01 per share, and vesting ratably on a quarterly basis over a three year period commencing March 31, 2018 and ending
December 31, 2020. There were no equity incentive compensation awards granted in 2017 to Dr. deGuzman. On April 28, 2016,
upon the consummation of our initial public offering, Dr. deGuzman was granted a stock option to purchase 278,726 shares of
our common stock at $5.00 per share, and vesting 3/36 on July 28, 2016 and 1/36 on each successive month thereafter from Aug
28, 2016 to April 28, 2019.



Upon
termination of employment, unless terminated by us without “cause” or by Dr. deGuzman with “good reason”
(as such terms are defined in the employment agreement), Dr. deGuzman will be entitled only to his base salary through the date
of termination, valid expense reimbursements and unused vacation pay. If terminated by us without “cause” or by him
with “good reason” (as such term are defined in the employment agreement), Dr. deGuzman is entitled
to be paid his base salary through the end of the term at the rate of 100%, valid expense reimbursements and accrued but unused
vacation pay.



Dr.
deGuzman’s employment agreement contains provisions for the protection of our intellectual property and contains non-compete
restrictions in the event of his termination other than by us without “cause” or by Dr. deGuzman with “good
reason” (generally imposing restrictions on (i) employment or consultation with competing companies or customers, (ii) recruiting
or hiring employees for a competing company and (iii) soliciting or accepting business from our customers for a period of six
months following termination). Pursuant to the agreement, Dr. deGuzman may serve as a consultant to, or on boards of directors
of, or in any other capacity to other companies provided that they will not interfere with the performance of his duties to us.



Potential
payments upon termination



As
indicated above, each of Dr. Aklog, Mr. McGrath, and Dr. deGuzman, is entitled to severance payments if his employment is terminated
under specified circumstances, pursuant to the respective employment agreement, each as described herein.





In
addition, our 2014 Long-Term Incentive Equity Plan provides that, in the event that a person or more than one person acting as
a group acquires more than 50% of the total fair market value or combined voting power of our stock in a transaction not approved
by the Board of Directors, all of the stock options under the plan, including the stock options held by our executive officers,
will automatically vest and become immediately exercisable in full. The plan also provides that, in the event a person or more
than one person acting as a group acquires more than 50% of the total fair market value or combined voting power of our stock
or more than 50% the total gross fair market value of all of our assets in a transaction approved by the Board of Directors, the
Board of Directors may either accelerate the vesting of all of the stock options under the plan, including the stock options held
by our executive officers, or require the holders of any award granted under the plan to relinquish such award to us for cash.
If the awards are not accelerated or required to be relinquished in connection with such an approved transaction, the awards will
continue in effect in accordance with their terms. The stock options granted by us outside of the plan, including the options
granted to our executive officers outside of the plan, have similar provisions. Furthermore, each of our stock options granted
in 2017 and 2018, including those granted to our executive officers, provide that such stock option will become immediately exercisable
as to all the underlying shares of our common stock upon the executive officer’s resignation with “good reason”
or upon a change in control of our company.



To
the extent any severance or other compensation payment to any of our executive officers pursuant to an employment agreement or
any other agreement constitutes an “excess parachute payment” within the meaning of Sections 280G and 4999 of the
Internal Revenue Code of 1986, as amended (the “Code”), then such executive officer will receive the full amount of
such severance and other payments, or a reduced amount intended to avoid the application of Sections 280G and 4999, whichever
provides the executive with the highest amount on an after-tax basis.



14







Item
11. Executive and Director Compensation (continued)



Consulting
Agreement - Named Executive Officer



Michael
J. Glennon - Vice Chairman



Along
with Drs. Lishan Aklog, M.D. and Brian J. deGuzman, M.D., Michael J. Glennon is our co-founder, and serves as our Vice
Chairman and member of our board of directors. To-date, Mr. Glennon has not earned a base salary or a bonus, nor has been remunerated
for serving on our board of directors, and no such salary, bonus, fees, or other remuneration are owed to Mr. Glennon.



On
February 14, 2018, the compensation committee of the board of directors authorized the grant to Mr. Glennon of a stock
option to purchase 100,000 shares of our common stock, having a February 14, 2018 grant date, an exercise price of
$2.01 per share, and vesting ratably on a quarterly basis over a three year period commencing March 31, 2018 and ending
December 31, 2020. There were no equity incentive compensation awards granted in 2017 to Mr. Glennon. On April 28, 2016, upon
the consummation of our initial public offering, Mr. Glennon was granted a stock option to purchase 278,726 shares of our
common stock at $5.00 per share, and vesting 3/36 on July 28, 2016 and 1/36 on each successive month thereafter from Aug 28,
2016 to April 28, 2019.



Effective
June 30, 2017, we mutually agreed with Mr. Glennon to terminate the consulting agreement between us and Mr. Glennon previously
effective October 1, 2016, under which Mr. Glennon agreed to provide us with services and advice relating to the successful development
and commercialization of medical device products. Effective as of December 31, 2016, Mr. Glennon waived his right to compensation
under the consulting agreement for the year ended December 31, 2016, and, effective as of March 31, 2017, Mr. Glennon further
waived his right to compensation under the consulting agreement for the period January 1, 2017 through June 30, 2017.



15







Item
11. Executive and Director Compensation (continued)



Director
Compensation



Each
of our non-executive Directors receive remuneration of an annual retainer fee of $40,000 and an additional annual fee for
service on a committee of the board of directors, as listed below. We also reimburse Directors for out-of-pockets costs incurred
to attend board and committee meetings.



|                           |  | Chair |        |  | Member |  
|-------------------------- |  | ----- | ------ |  | ------ | -
|Audit
    Committee        |  | $     | 20,000 |  |        | $
|Compensation
    Committee |  | $     | 15,000 |  |        | $
|Nominating
    Committee   |  | $     | 10,000 |  |        | $



The
following table sets forth summarized compensation awarded to, earned by or paid to our non-employee directors, for 2017 and 2016.



|                                 |  |           |        |  | Equity            |   |        |               |  |   |         |    
|-------------------------------- |  | --------- | ------ |  | ----------------- | - | ------ | ------------- |  | - | ------- | ---
|                                 |  |           |        |  | Incentive         |   |        |               |  |   |         |    
|                                 |  |           |        |  | Awards            |   |        |               |  |   |         |    
|                                 |  | Fees      |        |  | Estimated         |   |        | All
    Other |  |   |         |    
|Name                             |  | Earned(i) |        |  | Fair
    Value(2) |   |        | Compensation  |  |   | Totals  |    
|Ronald
    M. Sparks             |  | $         | 58,333 |  |                   | $ | —      |               |  | $ | —       |    
|Dr.
    James L. Cox, M.D.       |  | $         | 52,500 |  |                   | $ | —      |               |  | $ | —       |    
|Dr.
    David S. Battleman, M.D. |  | $         | 25,833 |  |                   | $ | 57,436 |               |  | $ | —       |    
|David
    Weild IV               |  | $         | 70,000 |  |                   | $ | —      |               |  | $ | —       |    
|Joshua
    R. Lamstein           |  | $         | 60,000 |  |                   | $ | —      |               |  | $ | —       |    
|Ira
    S. Greenspan             |  | $         | 40,000 |  |                   | $ | —      |               |  | $ | 380,000 | (3)



|(1) | Represents
    annual director fees paid, except for Dr. Battleman, for whom such amount represents director fees for the period August
    3, 2017 to December 31, 2017. The director fees paid to each person listed are consistent with the director fees described
    herein above, including annual retainer and as a member or chair of a committee of the board of directors.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
|--- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
|(2) | The
    amounts reported under “Equity Incentive Awards Estimated Fair Value” is the estimated grant date fair value of
    stock options granted during the respective year, as presented in the non-executive Directors “Stock Option Grants”
    table herein below, with such amount as determined under the provisions of Financial Accounting Standards Board (FASB)
    Accounting Standard Codification (ASC) Topic 718 (ASC 718), with respect to accounting for stock-based compensation expense.
    Such estimated fair value amounts do not necessarily correspond to the potential actual value realized of such stock options.
    The assumptions made in computing the estimated fair value of such stock options are discussed in our consolidated financial
    statements Note 2, Summary of Significant Accounting Policies - Stock Based Compensation, and Note 10, Stock Based Compensation,
    as included in our Annual Report on Form 10K for the year ended December 31, 2017, previously filed with the SEC on March
    14, 2018.



|(3) | The
    total amount of $380,000 is comprised of: (i) $300,000 paid to HCP /Advisors LLC, and (ii) $80,000 paid to HCFP /Strategy
    Advisors LLC, each of which such entity is an affiliate of Mr. Greenspan. See herein below under Item 13, Certain Relationships
    and Related Transactions, and Director Independence, for further information regarding payments to each such entity.
|--- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



16







Item
11. Executive and Director Compensation (continued)



Director
Compensation (continued)



The
outstanding stock options held by our non-executive Directors at December 31, 2017, as follows:



|                                 |  | Stock
    Option Grants(1)
|-------------------------------- |  | --------------------------
|                                 |  | Number                    
|                                 |  | of                        
|                                 |  | Securities                
|                                 |  | Underlying                
|                                 |  | Stock                     
|                                 |  | Options                   
|Name                             |  | Exercisable               
|Ronald
    M. Sparks             |  |                           
|Dr.
    James L. Cox, M.D.       |  |                           
|Dr.
    David S. Battleman, M.D. |  |                           
|David
    Weild IV               |  |                           
|Joshua
    R. Lamstein           |  |                           
|Ira
    S. Greenspan             |  |                           



|(1) | In
    connection with his appointment to our board of directors, on August 2, 2017, Dr. Battleman was granted a stock option to
    purchase 40,000 shares of our common stock at an exercise price of $2.98 per share and vesting ratably on a quarterly basis
    over a three year period commencing September 30, 2017 to June 30, 2020. There were no equity incentive compensation awards
    granted in 2017 to Mr. Sparks, Dr. Cox, Messrs. Weild, Lamstein, and Greenspan.
|--- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Previously,
on April 28, 2016, upon the consummation of our initial public offering, each of Mr. Sparks Dr. Cox, and Messrs. Weild, Lamstein,
and Greenspan were granted a stock option to purchase 97,554 shares of our common stock at $5.00 per share, and vesting 3/36 on
July 28, 2016 and 1/36 on each successive month thereafter from Aug 28, 2016 to April 28, 2019. Subsequently, upon their resignation
as members of our board of directors, effective February 12, 2018, 97,554 stock options granted on April 28, 2016 to each of Messrs.
Greenspan and Lamstein were forfeited under the terms of the respective stock option agreement.



Subsequently,
on February 14, 2018, the compensation committee of the board of directors authorized the grants of a stock option to purchase
100,000 shares of our common stock to each of Mr. Sparks, Dr. Cox, Dr. Battleman, and Mr. Weild, with such stock options having
a February 14, 2018 grant date, an exercise price of $2.01 per share, and vesting ratably on a quarterly basis over a three year
period commencing March 31, 2018 and ending December 31, 2020.



17







Item
12. Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters



The
following table sets forth information regarding the beneficial ownership of our shares of common stock as of April 25,
2018 by: each person known by us to be the beneficial owner of more than 5% of our outstanding shares; each of our officers and
directors; and, all our officers and directors as a group. We believe all persons named in the table have sole voting and investment
power with respect to all shares beneficially owned by them, unless other indicated.



|                                                                        |  | Amount        |           |     |         | 
|----------------------------------------------------------------------- |  | ------------- | --------- | --- | ------- | 
|                                                                        |  | and           |           |     |         | 
|                                                                        |  | Nature
    of |           |     | Percent | 
|                                                                        |  | Beneficial    |           |     | of      | 
|Name
    and Address of Beneficial Owner(1)                             |  | Ownership     |           |     | Class   | 
|                                                                        |  |               |           |     |         | 
|Lishan
    Aklog, M.D.                                                  |  |               | 9,233,709 | (2) |         | 
|Dennis
    M. McGrath                                                   |  |               | 111,595   | (3) |         | 
|Michael
    J. Glennon                                                  |  |               | 201,897   | (4) |         | 
|Brian
    J. deGuzman, M.D.                                             |  |               | 201,897   | (4) |         | 
|Ronald
    M. Sparks                                                    |  |               | 76,087    | (5) |         | 
|James
    L. Cox, M.D.                                                  |  |               | 76,087    | (5) |         | 
|David
    S. Battleman, M.D.                                            |  |               | 18,340    | (5) |         | 
|David
    Weild IV                                                      |  |               | 76,087    | (5) |         | 
|Pavilion
    Venture Partners LLC                                       |  |               | 5,566,836 | (6) |         | 
|HCFP/Capital
    Partners III LLC                                       |  |               | 2,823,281 | (7) |         | 
|All
    directors and executive officers as a group (eight individuals) |  |               | 9,995,699 |     |         | 



*
Represents less-than one percent-of-class.



|(1) | The
    business address of each of the individuals is One Grand Central Place, 60 E. 42nd Street, Suite 4600, New York,
    New York 10165, unless otherwise indicated.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
|--- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
|(2) | Includes:
                                         (i) 4,456,570 shares of common stock and 1,110,266 Series Z Warrants held by Pavilion
                                         Venture Partners LLC (“PVP”), of which Dr. Aklog is a member and sole manager,
                                         and, accordingly, he is deemed to have voting and dispositive power over such shares
                                         held by PVP; (ii) 20,000 shares of common stock and 10,000 Series Z Warrants held by
                                         HCFP/AG LLC and, 2,823,281 Series Z Warrants
                                         held by HCFP/Capital Partners III LLC, of which Dr. Aklog is a co-manager, and, accordingly,
                                         he is deemed to have joint voting and dispositive power over such shares of common stock
                                         and Series Z Warrants held by such entities; (iii) 590,998 shares of common stock 12,775
                                         Series Z Warrants held by Dr. Aklog; and (iv) 209,819 shares of common stock issuable
                                         upon the potential exercise of stock options granted to Dr. Aklog which have vested and
                                         are expected to vest within sixty days as of April 23, 2018. . Notwithstanding the foregoing,
                                         Dr. Aklog disclaims beneficial ownership of the shares of common stock and Series Z Warrants
                                         held by PVP, HCFP/AG LLC and HCFP/Capital Partners II LLC, except to the extent of his
                                         proportionate pecuniary interest therein.
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
|(3) | Includes
    12,000 shares of common stock held by Mr. McGrath, and 99,595 shares of common stock issuable upon the potential exercise
    of stock options granted to Mr. McGrath which have vested and are expected to vest within sixty days as of April 23, 2018.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
|(4) | Includes
    201,897 shares of common stock issuable upon the potential exercise of stock options granted to Mr. Glennon and Dr. deGuzman
    which have vested and are expected to vest within sixty days as of April 23, 2018.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
|(5) | Includes
    76,087 shares of common stock issuable upon the potential exercise of stock options granted to Mr. Sparks, Dr. Cox, and Mr.
    Weild, and 18,340 shares of common stock issuable upon the potential exercise of stock options granted to Dr. Battleman, each
    of which have vested and are expected to vest within sixty days as of April 23, 2018.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
|(6) | Includes
    4,456,570 shares of common stock and 1,110,266 Series Z Warrants.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              
|    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
|(7) | Includes
    2,823,281 Series Z Warrants.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   



18







Item
12. Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters (continued)



Equity
Compensation Plans



As
of December 31, 2017, we had the following compensation plans (including individual compensation arrangements) under which equity
securities were authorized for issuance:



|                                                                 |  | Number
    of |           |  |             |   |      | Number
    of | 
|---------------------------------------------------------------- |  | ------------- | --------- |  | ----------- | - | ---- | ------------- | 
|                                                                 |  | Securities    |           |  | Weighted    |   |      | Securities    | 
|                                                                 |  | to
    be     |           |  | Average     |   |      | Remaining     | 
|                                                                 |  | Issued        |           |  | Exercise    |   |      | Available     | 
|                                                                 |  | Upon          |           |  | Price       |   |      | for           | 
|                                                                 |  | Exercise      |           |  | of          |   |      | Future        | 
|                                                                 |  | of            |           |  | Outstanding |   |      | Issuance      | 
|                                                                 |  | Stock         |           |  | Stock       |   |      | Under         | 
|                                                                 |  | Options,      |           |  | Options,    |   |      | Equity        | 
|                                                                 |  | Warrants,     |           |  | Warrants,   |   |      | Compensation  | 
|                                                                 |  | Rights        |           |  | Rights      |   |      | Plans*        | 
|Plan
    Category                                                |  | (a)           |           |  | (b)         |   |      | (c)           | 
|Equity
    compensation plan approved by security holders        |  |               | 1,436,070 |  |             | $ | 5.09 |               | 
|Equity
    compensation plan not approved by security holders(2) |  |               | 500,854   |  |             | $ | 5.47 |               | 
|Total                                                            |  |               | 1,936,924 |  |             | $ | 5.19 |               | 



*Excluding securities included in column (a).



| | (1) | Represents
    shares of common stock available for issuance under our 2014 Long-Term Incentive Equity Plan.                                                                                                                                                                                                                                                         
| | --- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
| |     |                                                                                                                                                                                                                                                                                                                                                                      
| | (2) | Represents:
    (i) 83,618 stock options issued to each of Dr. Aklog, Mr. Glennon, and Dr. deGuzman, on April 28, 2016, which were in excess
    of the annual grant limit of 195,108 shares within our 2014 Long-Term Incentive Equity Plan; and (ii) 250,000 stock options
    issued to Mr. McGrath upon commencement of his employment with us on March 20, 2017.



19







Item
13. Certain Relationships and Related Transactions, and Director Independence



The
following is a description of transactions during the period commencing January 1, 2016 to which we have been a party,
and in which any of our directors, named executive officers, holders of more than 5% of our voting securities, and affiliates
of our directors, named executive officers, and holders of more than 5% of our voting securities, had or will have a direct or
indirect material interest. The following description also includes certain transactions since our inception on June 26, 2014
with individuals who may be deemed our promoters. We believe all of the transactions described below were made on terms no
less favorable to us than could have been obtained from unaffiliated third parties.



Compensation
arrangements for our directors and named executive officers are described elsewhere in this Form 10-K/A.



The
information in this section reflects the forward stock split of 2.7872582-for-1 by way of a stock dividend of 1.7872582 shares
for each outstanding share effectuated in September 2015.



In
June 2014 in connection with our organization, we issued (i) 5,658,134 shares of common stock for proceeds of $2,030, and warrants
to purchase an additional 6,097,127 shares of common stock, at an exercise price of  $0.90 per share for proceeds of $218.75,
for an aggregate purchase price and total consideration of $2,248.75, to HCFP/Capital Partners III LLC, an affiliate of Dr. Aklog,
Mr. Glennon, and Dr. deGuzman, along with former members of our board of directors, Mr. Ira S. Greenspan and Mr. Joshua R. Lamstein,
each of whom resigned from the board of directors effective February 12, 2018; and, (ii) 2,424,915 shares of common stock for
proceeds of $870.00, and warrants to purchase an additional 2,613,054 shares of common stock, at an exercise price of $0.90 per
share, for proceeds of $93.75, for an aggregate purchase price and total consideration of  $963.75, to Pavilion Venture
Partners LLC, an affiliate of Dr. Aklog, Mr. Glennon, and Dr. deGuzman.



In
July 2014, we issued 418,089 units, each consisting of one share of common stock and one warrant to purchase one share of common
stock at an exercise price of  $0.90, for $75,000 in cash, or a purchase price of  $0.18 per unit, of which 13,936
of such units were sold to Robert M. Greenspan, the son of Mr. Greenspan, a former member of our board of directors, as noted
above. The table below sets forth the number of such units sold to our directors, named executive officers, or holders of more
than 5% of our capital stock:



|Name                              |  | Number
    of Shares of Common Stock included in
    Units |        |  | Number
    of Warrants included in 
    Units |  |        | Relationship
    to Us
|--------------------------------- |  | ---------------------------------------------------------- | ------ |  | --------------------------------------------- |  | ------ | ----------------------
|HCFP/Capital
    Partners III LLC |  |                                                            | 55,745 |  |                                               |  | 55,745 |                       
|                                  |  |                                                            |        |  |                                               |  |        |                       
|Pavilion
    Venture Partners LLC |  |                                                            | 83,618 |  |                                               |  | 83,618 |                       
|                                  |  |                                                            |        |  |                                               |  |        |                       
|Ira
    Scott Greenspan           |  |                                                            | 27,873 |  |                                               |  | 27,873 |                       
|                                  |  |                                                            |        |  |                                               |  |        |                       
|Joshua
    R. Lamstein            |  |                                                            | 83,617 |  |                                               |  | 83,617 |                       



In
October 2014, HCFP/Capital Partners III and Pavilion Venture Partners LLC contributed an aggregate of 438,993 and 188,140 warrants,
respectively, to the capital of PAVmed Inc. for no consideration.



In
November 2014, we issued 2,355,233 units, each consisting of one share of common stock and one warrant to purchase one share of
common stock at an exercise price of  $0.90, for $845,000 in cash, or a purchase price of  $0.36 per unit, of which
139,363 units were sold to Matthew J. Glennon, who is the brother of Mr. Glennon, our Vice Chairman and a member of our board
of directors.



In
September 2015, warrants to purchase 1,393,629 shares were exercised by the holders generating an aggregate of  $1.25 million
of proceeds to us, including warrants to purchase 6,968 shares exercised by Robert M. Greenspan the son of Mr. Greenspan, a former
member of our board of directors, as noted above. Thereafter, we effectuated the forward stock split by way of a stock dividend
as described above resulting in 12,250,000 common shares outstanding.



20







Item
13. Certain Relationships and Related Transactions, and Director Independence (continued)



Pursuant
to their terms, each outstanding warrant not exercised prior to the closing of our initial public offering on April 28, 2016 was
automatically converted into a warrant with the same terms as the warrants offered in the initial public offering, which are referred
to as Series W Warrants.



In
September 2014, we entered into an option agreement with Pavilion Holdings Group LLC, an affiliate of Pavilion Venture Partners
LLC which is an affiliate of Dr. Aklog, pursuant to which we had the option to acquire all rights, title, and interest in and
to a certain patent related to a medical infusion device for an aggregate of  $10,000 at any time until September 2015.
We exercised this option in September 2015 and we now own this patent along with associated patent applications.



Effective
October 27, 2015, we entered into a management services agreement from October 1, 2015 through October 31, 2018 with HCP/Advisors
LLC, an affiliate of Mr. Greenspan, a former member of our board of directors, as noted above, wherein, HCP/Advisors LLC is to
provide us with certain management services and consulting, including without limitation, identifying potential corporate opportunities,
general business development, corporate development, corporate governance, marketing strategy, strategic development and planning,
coordination with service providers, and other advisory services as may be mutually agreed upon. Pursuant to such agreement, payments
by us to HCP/Advisors LLC, include an initial fee of $35,000 for the one-month November 2015, and thereafter, a monthly fee of $25,000
from December 2015 through October 2018.



The
management service agreement may be terminate by either us or HCP /Advisors LLC prior to the expiration of the term if the other
party materially breaches the terms of the agreement and such breach has not been cured within 30 days of notice of the same.
Additionally, we have the right to terminate the agreement if HCP/Advisors LLC commits any fraud or dishonest action in its relations
with us or any of our subsidiaries or affiliates. If HCP/Advisors LLC terminates the agreement because of our material breach
which is not thereafter cured or we terminate the agreement for any reason other than HCP /Advisors LLC material breach, we will
be required to pay HCP/Advisors LLC all amounts due under the agreement for the remainder of the term within 30 days of termination.
In all other cases, we will only be obligated to pay HCP/Advisors LLC the amounts owed through the date of termination.



Effective
September 2016, the Company and HCFP/Strategy Advisors LLC, an affiliate of certain former directors and current named executive
officers of the Company, entered into a management consulting agreement referred to as the “HCFP Strategic Advisory Agreement”,
which expired on May 14, 2017, as discussed below. Under the HCFP Strategic Advisory Agreement, HCFP/Strategy Advisors LLC had
been engaged for an initial term of five months from September 14, 2016 to February 14, 2017, to provide various management consulting
advisory services, including: to provide strategic business planning, to identify and assist with potential sources of financing
arrangements, to promote the Company to various potential investors, and to provide strategic advisory services as reasonably
requested by the Company. The HCFP Strategic Advisory Agreement provided for an initial total fee of $110,000, with $30,000 paid
upon execution of the agreement and four payments of $20,000 per month from October 2016 to January 2017. Subsequently, on February
17, 2017, the Company and HCFP/Strategy Advisors LLC executed an extension of the HCFP Strategic Advisory Agreement, effective
as of February 15, 2017, extending the services from February 15, 2017 to May 14, 2017, and obligating the Company to make payments
of $20,000 per month in each of February, March, and April 2017. The Company did not further renew the HCFP Strategic Advisory
Agreement after the May 14, 2017 expiration date. Previously, at December 31, 2016, the Company recognized a $10,000 estimated
accrued expense liability for HCFP/Strategy Advisors LLC asserted out-of-pocket expenses under the HCFP Strategic Advisory Agreement
in effect as of December 31, 2016. Subsequently, at June 30, 2017, the Company reversed such $10,000 estimated accrued expense
liability, as supporting documentation had not been provided by HCFP/Strategy Advisors LLC. At June 30, 2017, the Company had
made all contractually obligated payments to, and disclaimed any further payment obligations, under the HCFP Strategic Advisory
Agreement.



Separately,
the Company incurred an expense of $10,000 related to a HCFP/Strategy Advisors LLC vendor invoice dated June 30, 2017, for a professional
services fee related to separate discrete discussions between the Company’s management and HCFP /Strategy Advisors LLC,
conducted between the period of May 15, 2017 to May 31, 2017 regarding corporate matters, which were separate and apart from the
previously expired HCFP Strategic Advisory Agreement.



Effective
September 2016, the Company also entered into a consulting agreement with Swartwood Hesse, Inc., an affiliate of HCFP/Strategy
Advisors (which, as noted above, is an affiliate of certain former directors and current names executive officers of the Company)
(the “Swartwood Hesse Financial Advisory Agreement”). Under the Swartwood Hesse Financial Advisory Agreement, Swartwood
Hesse Inc. was engaged for an initial term of five months to provide advisory services regarding potential financing arrangements,
to assist the Company with its investors relations, and to provide other financial advisory services as reasonably requested by
the Company. The Swartwood Hesse Financial Advisory Agreement provided for total fee of $15,000, as paid upon execution of the
agreement. The Swartwood Hess Financial Advisory Agreement was not further renewed nor extended after its January 2017 expiration
date.



21







Item
13. Certain Relationships and Related Transactions, and Director Independence (continued)



In
January 2017, the Company entered into an agreement with Xzerta Trading LLC d/b/a HCFP/Capital Markets (“HCFP/Capital Markets”),
an affiliate of certain former directors and current named executive officers of the Company, wherein HCFP/Capital Markets was
engaged to be the Company’s exclusive placement agent in an offering of securities in the Series A Preferred Stock Units
private placement transaction (“the HCFP/Capital Markets Placement Agent Agreement”), under which, HCFP/Capital Markets
was paid a fee of 7.0% of the gross proceeds realized in the Series A Preferred Stock Units private placement transaction, plus
reimbursement of certain out-of-pocket costs. The term of the HCFP/Capital Markets Placement Agent Agreement is from the January
2017 execution date to the completion or termination of any other potential transactions in conjunction with the Series A Preferred
Stock Units private placement. The Company incurred $177,576 of fees paid to HCFP/Capital Markets in connection with the issuances
of Series A Preferred Stock Units in the year ended December 31, 2017.



Effective
November 2016, we entered into a consulting agreement with Mr. Patrick Glennon, the brother of Mr. Glennon, our Vice Chairman
and a member of our board of directors. Under the terms of the consulting agreement, Mr. Patrick Glennon will provide us with
consulting support and advice with respect to the development and commercialization of resorbable ear tubes, with the sole compensation
for such services is the issuance on November 28, 2016 of stock options to purchase 20,000 shares of our common stock, with an
exercise price of $9.50 per share, and vesting ratably on a quarterly basis commencing December 31, 2016 through September 30,
2019.



We
will reimburse our founders and members of our management team and their affiliates for any reasonable out-of-pocket business
expenses incurred by them in connection with activities on our behalf. There is no limit on the amount of accountable out-of-pocket
expenses reimbursable by us, which will be reviewed only by our board of directors or a court of competent jurisdiction if such
reimbursement is challenged.



All
ongoing and future transactions between us and any of our named executive officers and directors or their respective affiliates
will be on terms believed by us to be no less favorable to us than as available from unaffiliated third parties. Such transactions
will require prior approval by a majority of our uninterested “independent” directors (to the extent we have any)
or the members of our board who do not have an interest in the respective transaction, in either case who had access, at our expense,
to our attorneys or independent legal counsel. We will not enter into any such transaction unless our disinterested “independent”
directors (or, if there are no “independent” directors, our disinterested directors) determine the terms of such transaction
are no less favorable to us than those available to us with respect to such a transaction from unaffiliated third parties.



Related
Party Policy



Our
Code of Ethics requires that we avoid, wherever possible, all related party transactions that could result in actual or potential
conflicts of interests, except under guidelines approved by the Board of Directors. Related party transactions are defined under
SEC rules as transactions in which (1) the aggregate amount involved will or may be expected to exceed the lesser of  $120,000
or one percent of the average of our total assets in any calendar year, (2) we or any of our subsidiaries is a participant, and
(3) any (a) executive officer, director or nominee for election as a director, (b) greater than 5% beneficial owner of our shares
of common stock, or (c) immediate family member, of the persons referred to in clauses (a) and (b), has or will have a direct
or indirect material interest (other than solely as a result of being a director or a less than 10% beneficial owner of another
entity). A conflict of interest situation can arise when a person takes actions or has interests that may make it difficult to
perform his or her work objectively and effectively. Conflicts of interest may also arise if a person, or a member of his or her
family, receives improper personal benefits as a result of his or her position.



No
director may participate in the approval of any transaction in which he is a related party, but that director is required to provide
the other members of the board with all material information concerning the transaction. Additionally, we require each of our
directors and executive officers to complete a directors’ and officers’ questionnaire that elicits information about
related party transactions.



These
procedures are intended to determine whether any such related party transaction impairs the independence of a director or presents
a conflict of interest on the part of a director, employee or officer.



Director
Independence



Our
common stock is listed on the Capital Market of The NASDAQ Stock Market (“Nasdaq”) and the Company adheres to the
Nasdaq listing standards in determining whether a director is independent. The Board consults with its counsel to ensure that
its determinations are consistent with those rules and all relevant securities and other laws and regulations regarding the independence
of directors. Nasdaq requires that a majority of the Board must be composed of “independent directors,” which is defined
generally as a person other than an officer of a company, who does not have a relationship with the company that would interfere
with the director’s exercise of independent judgment in carrying out the responsibilities of a director. Consistent with
these considerations, the Company has determined that each of Drs. Cox and Battleman and Messrs. Weild and Sparks is an independent
director. The Company determined in August 2017 that Mr. Lamstein was no longer an independent director.



22







Item
14. Principal Accounting Fees and Services



The
following table summarizes the fees of Citrin Cooperman & Company, LLP, our independent registered public accounting firm,
billed to us for each of the last two years. (JJD to update table)



|                          |  | Year
    ended December 31, |        
|------------------------- |  | --------------------------- | -------
|                          |  | 2017                        |        
|Audit
    Fees(1)         |  | $                           | 116,440
|Audit-Related
    Fees(2) |  |                             | 118,415
|Tax
    Fees(3)           |  |                             | 9,550  
|All
    Other Fees        |  |                             | —      
|Total
    Fees            |  | $                           | 244,405



| | (1) | Audit
    fees consist of fees billed for professional services by Citrin Cooperman & Company, LLP for audit and quarterly review
    of our consolidated financial statements during the years ended December 31, 2017and 2016 and in connection with review of
    the registration statement on Form S-1 for our initial public offering, and related services normally provided in connection
    with statutory and regulatory filings or engagements.                         
| | --- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
| |     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
| | (2) | Audit
    related fees represent the aggregate fees billed for assurance and related professional services rendered by our independent
    registered public accounting firm reasonably related to the performance of the audit or review of our financial statements
    and are not reported under “Audit Fees” including the issuance of consents in connection with registration statement
    filings with the SEC and comfort letters in connection with securities offerings.
| |     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
| | (3) | Tax
    fees represent the aggregate fees billed for professional services rendered by our independent registered public accounting
    firm for tax compliance, tax advice, and tax planning services.                                                                                                                                                                                                                                                                             



The
aggregate fees included in the Audit Fees are those billed for the fiscal year. The aggregate fees included in the Audit-Related
Fees and Tax Fees are those fees billed in the fiscal year.



The
audit committee of our board of directors has adopted policies and procedures for the pre-approval of audit and non-audit services
for the purpose of maintaining the independence of our independent auditor. We may not engage our independent auditor to render
any audit or non-audit service unless either the service is approved in advance by the audit committee, or the engagement to render
service is entered into pursuant to the audit committee’s pre-approval policies and procedures. All accountant services
and fees noted above were pre-approved by our audit committee in accordance with such pre-approval procedures.



23







PART
IV



|Item
15. | Exhibits
|-------- | --------



|Exhibit
    No. |  | Description                                                                                                                                                                     
|--------------- |  | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|3.1             |  | Certificate
    of Incorporation(1)                                                                                                                                             
|3.2             |  | Certificate
    of Amendment to Certificate of Incorporation(1)                                                                                                                 
|3.3             |  | Form
    of Certificate of Designation of Preferences, Rights and Limitations of Series B Convertible Preferred Stock(8)                                                        
|3.4             |  | Form
    of Certificate of Designation of Preferences, Rights and Limitations of Series A Convertible Preferred Stock(2)                                                        
|3.5             |  | Form
    of Certificate of Designation of Preferences, Rights, and Limitations of Series A-1 Convertible Preferred Stock(6)                                                     
|3.5             |  | Bylaws(1)                                                                                                                                                                       
|4.1             |  | Specimen
    Common Stock Certificate(1)                                                                                                                                        
|4.2             |  | Specimen
    Series W Warrant Certificate(1)                                                                                                                                    
|4.3             |  | Series
    W Warrant Agreement, April 28, 2016, between Continental Stock Transfer & Trust Company and the Registrant (3)                                                       
|4.4             |  | Form
    of Unit Purchase Option(1)                                                                                                                                             
|4.5             |  | Form
    of Series A Warrant(2)                                                                                                                                                 
|4.6             |  | Form
    of Series X Warrant(2)                                                                                                                                                 
|4.7             |  | Form
    of Series A-1 Warrant(6)                                                                                                                                               
|10.1            |  | Patent
    Option Agreement(1)                                                                                                                                                  
|10.2.1*         |  | Employment
    Agreement between PAVmed and Dr. Lishan Aklog, M.D.(1)                                                                                                           
|10.2.2*         |  | Amendment
    to Employment Agreement between PAVmed and Dr. Lishan Aklog, M.D.(1)                                                                                              
|10.2.3*         |  | Second
    Amendment to Employment Agreement between PAVmed and Dr. Lishan Aklog, M.D.(1)                                                                                       
|10.2.4*         |  | Third
    Amendment to Employment Agreement between PAVmed and Dr. Lishan Aklog, M.D.(9)                                                                                        
|10.3.1          |  | Form
    of Subscription Agreement (July 2014)(1)                                                                                                                               
|10.3.2          |  | Form
    of Subscription Agreement (November 2014)(1)                                                                                                                           
|10.4.1          |  | Form
    of Letter Agreement with HCFP/Capital Partners III LLC(1)                                                                                                              
|10.4.2          |  | Form
    of Letter Agreement with Pavilion Venture Partners LLC(1)                                                                                                              
|10.5.1          |  | Letter
    agreement regarding corporate opportunities executed by Dr. Lishan Aklog, M.D.(1)                                                                                    
|10.5.2          |  | Letter
    agreement regarding corporate opportunities executed by Michael J. Glennon (1)                                                                                       
|10.5.3          |  | Letter
    agreement regarding corporate opportunities executed by Dr. Brian J. deGuzman, M.D.(1)                                                                               
|10.6            |  | Management
    services agreement between PAVmed and HCP/Advisors LLC(1)                                                                                                        
|10.7.1*         |  | Employment
    Agreement between PAVmed and Richard F. Fitzgerald(1)                                                                                                            
|10.7.2*         |  | Separation
    Agreement between PAVmed and Richard F. Fitzgerald(10)                                                                                                           
|10.7.3*         |  | Consulting
    Agreement between PAVmed and Richard F. Fitzgerald(10)                                                                                                           
|10.8*           |  | Employment
    Agreement between PAVmed and Dr. Brian J. deGuzman, M.D.(4)                                                                                                      
|10.9.1*         |  | Consulting
    Agreement between PAVmed and Michael J. Glennon(5)                                                                                                               
|10.9.2*         |  | Amendment
    to Consulting Agreement between PAVmed and Michael J. Glennon(9)                                                                                                  
|10.9.3*         |  | Amendment
    to Consulting Agreement between PAVmed and Michael J. Glennon(10)                                                                                                 
|10.9.4*         |  | Termination
    of Consulting Agreement between PAVmed and Michael J. Glennon(11)                                                                                               
|10.10.1         |  | Securities
    Purchase Agreement between PAVmed and the purchasers of the Series A Preferred Stock Units(2)                                                                    
|10.10.2         |  | Registration
    Rights Agreement between PAVmed and the purchasers of the Series A Preferred Stock Units(2)                                                                    
|10.11*          |  | 2014
    Long-Term Equity Incentive Plan(1)                                                                                                                                     
|10.12*          |  | Employment
    Agreement between PAVmed and Dennis M. McGrath(10)                                                                                                               
|10.14           |  | Note
    and Securities Purchase Agreement between PAVmed and Scopia Holdings LLC(7)                                                                                            
|10.15.1         |  | Securities
    Purchase Agreement between PAVmed and the purchasers of the Series A-1 Preferred Stock Units(2)                                                                  
|10.15.2         |  | Registration
    Rights Agreement between PAVmed and the purchasers of the Series A-1 Preferred Stock Units(2)                                                                  
|14              |  | Form of Code of Ethics(1)                                                                                                                                                       
|23.1            |  | Consent
    of Citrin Cooperman & Company, LLP(12)                                                                                                                              
|31.1            |  | Certification
    of Principal Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002**                                                                    
|31.2            |  | Certification
    of Principal Financial and Accounting Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002**                                                     
|32.1            |  | Certification
    of Principal Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley
    Act of 2002(12)               
|32.2            |  | Certification
    of Principal Financial and Accounting Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the
    Sarbanes-Oxley Act of 2002(12)





24









|Item
    15. | Exhibits (Continued)
|------------ | --------------------



|Exhibit
    No. |  | Description
|--------------- |  | -----------





|        |  |                                                      
|------- |  | -----------------------------------------------------
|101.INS |  | XBRL
    Instance Document(12)                       
|101.SCH |  | XBRL
    Taxonomy Extension Schema(12)               
|101.CAL |  | XBRL
    Taxonomy Extension Calculation Linkbase(12) 
|101.DEF |  | XBRL
    Taxonomy Extension Definition Linkbase(12)  
|101.LAB |  | XBRL
    Taxonomy Extension Label Linkbase(12)       
|101.PRE |  | XBRL
    Taxonomy Extension Presentation Linkbase(12)







| | (1)  | Incorporated
    by reference to the Registrant’s Registration Statement on Form S-1 (SEC File No. 333-203569)               
| | ---- | -----------------------------------------------------------------------------------------------------------------------------
| | (2)  | Incorporated
    by reference to the Registrant’s Current Report on Form 8-K filed on February 1, 2017.                      
| | (3)  | Incorporated
    by reference to the Registrant’s Current Report on Form 8-K filed on May 3, 2016.                           
| | (4)  | Incorporated
    by reference to the Registrant’s Current Report on Form 8-K filed on July 19, 2016.                         
| | (5)  | Incorporated
    by reference to the Registrant’s Current Report on Form 8-K filed on October 14, 2016.                      
| | (6)  | Incorporated
    by reference to the Registrant’s Current Report on Form 8-K filed on August 8, 2017.                        
| | (7)  | Incorporated
    by reference to the Registrant’s Current Report on Form 8-K filed on July 6, 2017.                          
| | (8)  | Incorporated
    by reference to the Registrant’s Current Report on Form 8-K/A filed on April 20, 2018                       
| | (9)  | Incorporated
    by reference to the Registrant’s Annual Report on Form 10-K (December 31, 2016), filed on February 16, 2017.
| | (10) | Incorporated
    by reference to the Registrant’s Quarterly Report on Form 10-Q filed on May 22, 2017.                       
| | (11) | Incorporated
    by reference to the Registrant’s Quarterly Report on Form 10-Q filed on August 11, 2017.                    
| | (12) | Incorporated
    by reference to the Registrant’s Annual Report on Form 10-K (December 31, 2017), filed on March 14, 2018.   
| | *    | Management
    contract or compensatory plan or arrangement.                                                                 
| | **   | Filed
    herewith.                                                                                                          



25









Item
16. Form 10-K Summary



None





26







SIGNATURES



Pursuant
to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf
by the undersigned hereunto duly authorized.



|                   | PAVmed
    Inc.
|------------------ | ---------------
|                   |                
|April
    30, 2018 | By:            
|                   |                
|                   |                
|                   |                



Pursuant
to the requirements of the Securities Exchange Act of 1934, as amended, the report has been signed by the following persons on
behalf of the Registrant and in the capacities and on the dates indicated. Each person whose signature appears below hereby authorizes
each of Lishan Aklog, M.D. and Dennis M. McGrath or either of them acting in the absence of the others, as his or her true and
lawful attorney-in-fact and agent, with full power of substitution and re-substitution for him or her and in his or her name,
place and stead, in any and all capacities to sign any and all amendments to this report, and to file the same, with all exhibits
thereto and other documents in connection therewith, with the Securities and Exchange Commission.



|Signature                  |  | Title                                            |  | Date              
|-------------------------- |  | ------------------------------------------------ |  | ------------------
|                           |  |                                                  |  |                   
|/s/
    Lishan Aklog, M.D. |  | Chairman
    of the Board of Directors           |  | April
    30, 2018
|Lishan
    Aklog, M.D.     |  | Chief
    Executive Officer                      |  |                   
|                           |  | (Principal
    Executive Officer)                |  |                   
|                           |  |                                                  |  |                   
|/s/
    Dennis M. McGrath  |  | Executive
    Vice President                     |  | April
    30, 2018
|Dennis
    M. McGrath      |  | Corporate
    Secretary                          |  |                   
|                           |  | Chief
    Financial Officer                      |  |                   
|                           |  | (Principal
    Financial and Accounting Officer) |  |                   
|                           |  |                                                  |  |                   
|/s/
    Michael J. Glennon |  | Vice
    Chairman                                |  | April
    30, 2018
|Michael
    J. Glennon     |  | Director                                         |  |                   
|                           |  |                                                  |  |                   
|/s/
    Ronald M. Sparks   |  | Director                                         |  | April
    30, 2018
|Ronald
    M. Sparks       |  |                                                  |  |                   
|                           |  |                                                  |  |                   
|/s/
    James L. Cox, M.D. |  | Director                                         |  | April
    30, 2018
|James
    L. Cox, M.D.     |  |                                                  |  |                   
|                           |  |                                                  |  |                   
|/s/
    David S. Battleman |  | Director                                         |  | April
    30, 2018
|David
    S. Battleman     |  |                                                  |  |                   
|                           |  |                                                  |  |                   
|/s/
    David Weild IV     |  | Director                                         |  | April
    30, 2018
|David
    Weild IV         |  |                                                  |  |                   



27