CDC - NIOSH Pocket Guide to Chemical Hazards - Toluene-2,4-diisocyanate

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## NIOSH Home NIOSH Pocket Guide to Chemical Hazards NIOSH Pocket Guide to Chemical Hazards Introduction Search the Pocket Guide Chemical Names, Synonyms and Trade Names A B C D E F G H I J K L M N O P Q R S T U V W X Y Z CAS Numbers RTECS Numbers Appendices A - NIOSH Potential Occupational Carcinogens B - Thirteen OSHA-Regulated Carcinogens C - Supplementary Exposure Limits D - Substances with No Established RELs E - OSHA Respirator Requirements for Selected Chemicals F - Miscellaneous Notes G - 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect Type C & CE - Definitions for Type C and Type CE Respirators Personal Protection and Sanitation CodesCDC - NIOSH Pocket Guide to Chemical Hazards - Toluene-2,4-diisocyanate

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# Toluene-2,4-diisocyanate

Synonyms & Trade Names TDI; 2,4-TDI; 2,4-Toluene diisocyanate

CAS No. 584-84-9 RTECS No. CZ6300000 DOT ID & Guide 2078 156

Formula CH 3 C 6 H 3 (NCO) 2 Conversion 1 ppm = 7.13 mg/m 3 IDLH Ca [2.5 ppm] See: 584849 Facebook Reccomend 2 Twitter Tweet 0 Share Compartir Add this to... Añadir en... Favorites Delicious Digg Google Bookmarks LinkedIn PinterestCDC - NIOSH Pocket Guide to Chemical Hazards - Toluene-2,4-diisocyanate

https://www.fdms.gov/fdms-web-agency/component/contentstreamer?objectId=0900006481590ef2&format=html&disposition=attachment [2/20/2014 12:57:17 PM] Exposure Limits

NIOSH REL : Ca See Appendix A

OSHA PEL † : C 0.02 ppm (0.14 mg/m 3 ) Measurement Methods

NIOSH 2535 , 5521 , 5522

, 5525 ; OSHA 18 , 33 , 42
See: NMAM or OSHA Methods
Physical Description Colorless to pale-yellow solid or liquid (above 71°F) with a sharp, pungent odor.

MW: 174.2 BP: 484°F MLT: 71°F Sol: Insoluble VP(77°F): 0.01 mmHg IP: ?
Sp.Gr: 1.22 Fl.P: 260°F UEL: 9.5% LEL: 0.9% Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
Incompatibilities & Reactivities Strong oxidizers, water, acids, bases & amines (may cause foam & spatter); alcohols [Note: Reacts slowly with water to form carbon dioxide and polyureas.]
Exposure Routes inhalation, ingestion, skin and/or eye contact
Symptoms irritation eyes, skin, nose, throat; choke, paroxysmal cough; chest pain, retrosternal (occurring behind the sternum) soreness; nausea, vomiting, abdominal pain; bronchitis, bronchospasm, pulmonary edema; dyspnea (breathing difficulty), asthma; conjunctivitis, lacrimation (discharge of tears); dermatitis, skin sensitization; [potential occupational carcinogen]
Target Organs Eyes, skin, respiratory system

Cancer Site [in animals: pancreas, liver, mammary gland, circulatory sys & skin tumors]

Personal Protection/SanitationCDC - NIOSH Pocket Guide to Chemical Hazards - Toluene-2,4-diisocyanate

https://www.fdms.gov/fdms-web-agency/component/contentstreamer?objectId=0900006481590ef2&format=html&disposition=attachment [2/20/2014 12:57:17 PM] ( See protection codes ) Skin: Prevent skin contact Eyes: Prevent eye contact Wash skin: When contaminated/Daily Remove: When wet or contaminated Change: Daily Provide: Eyewash, Quick drench First Aid ( See procedures ) Eye: Irrigate immediately Skin: Soap wash immediately Breathing: Respiratory support Swallow: Medical attention immediately

Respirator Recommendations NIOSH At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode (APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister Any appropriate escape-type, self-contained breathing apparatus Important additional information about respirator selection See also: INTRODUCTION See ICSC CARD: 0339 See MEDICAL TESTS: 0233 Email page link Print page Get email updates Subscribe to RSS Listen to audio/Podcast Order NIOSH Publications Order Online 1-800-CDC-INFO Order from NTIS
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