Exhibit 10.11




COLLATERAL ASSIGNMENT OF


TRADEMARKS, TRADEMARK

APPLICATIONS,


PATENTS AND PATENT

APPLICATIONS




THIS

COLLATERAL ASSIGNMENT OF TRADEMARKS, TRADEMARK APPLICATIONS, PATENTS AND PATENT

APPLICATIONS is made as of December 7, 2001 by and among HAUSER, INC., a

Delaware corporation, HAUSER TECHNICAL SERVICES, INC., a Delaware Corporation,

BOTANICALS INTERNATIONAL EXTRACTS, INC., a Delaware corporation, ZETAPHARM,

INC., a New York corporation, (each, an “Assignor” and collectively, the

“Assignors”), and Wells Fargo Bank, National Association (the “Assignee”).




W I T N E S S E T H:




WHEREAS,

Assignors are the owners of certain trademarks, trademark applications, patents

and patent applications listed in Exhibit A attached to this document; and




WHEREAS,

Assignors and Assignee have entered into that certain Amended and Restated

Credit Agreement dated as of December 7, 2001 (as from time to time amended,

modified or supplemented, the “Credit Agreement”), pursuant to which, upon the

satisfaction by the Assignors of the terms and conditions contained therein,

Assignee will make loans to Assignors; and




WHEREAS,

pursuant to the Credit Agreement, Assignors have agreed to grant Assignee a

security interest in all of their right, title and interest in and to the

trademarks, trademark applications, patents and patent applications described

in Exhibit A, and in and to the goodwill symbolized by such trademarks (the

“Goodwill”), as collateral security for the Obligations as defined in the

Credit Agreement; and




WHEREAS,

except as noted on Exhibit A attached to this document, Assignors are the

owners of the entire right, title and interest in the trademarks, trademark

applications, patents and patent applications being assigned hereby.




NOW,

THEREFORE, in consideration of the foregoing and other good and valuable

consideration, Assignors hereby:




1.             Assign, pledge and grant to

Assignee, as security for the Obligations, a security interest in and to the

trademarks, trademark applications, patents and patent applications listed in Exhibit

A attached to this document, and to the Goodwill, and a security interest in

and to all trademarks, trademark applications, Goodwill, patents and patent

applications acquired by Assignors after the date hereof.




 




 





























 




2.             Authorize and request the Commissioner

of Patents and Trademarks of the United States of America and the empowered

officials of all other governments to note in the record the existence of the

security interest granted hereunder with respect to each of the trademarks,

trademark applications, patents and patent applications listed in Exhibit A

attached to this document, and to the Goodwill, and to all trademarks,

trademark applications, Goodwill, patents and patent applications acquired by

Assignors after the date hereof.




3.             Acknowledge that notices and other

communications shall be in writing and given as provided in Section 9.01 of the

Credit Agreement. Communications and notices to any Assignor shall be given to

it at its address set forth in Exhibit B attached to this document.




4.             Agree upon the request of Assignee

and at the expense of Assignors to take any reasonable actions and execute any

documents necessary to effectuate this assignment and the security interest

created in the trademarks, trademark applications, patents and patent

applications listed in Exhibit A to this document.




[Balance

of Page Intentionally Left Blank]




 




 





























IN

WITNESS WHEREOF, Assignors have caused this Assignment to be signed by their

respective authorized officers as of the day and year first above written.








	

   


  	

  ASSIGNEE:


  
	

   


  	

   


  
	

   


  	

  WELLS

  FARGO BANK, NATIONAL


  
	

   


  	

  ASSOCIATION


  
	

   


  	

   


  
	

  By:


  	

  /s/  Art Brokx


  
	

   


  	

  Name:  Art Brokx


  
	

   


  	

  Title:  VP


  
	

   


  	

   


  
	

   


  	

  ASSIGNORS:


  
	

   


  	

   


  
	

   


  	

  HAUSER,

  INC.


  
	

   


  	

   


  
	

  By:


  	

  /s/  Kenneth C. Cleveland


  
	

   


  	

  Name:  Kenneth C. Cleveland


  
	

   


  	

  Title:  Chief Executive Officer


  
	

   


  	

   


  
	

   


  	

  HAUSER

  TECHNICAL SERVICES, INC.


  
	

   


  	

   


  
	

  By:


  	

  /s/  Thomas W. Hanlon


  
	

   


  	

  Name:  Thomas W. Hanlon


  
	

   


  	

  Title:  Secretary and Treasurer


  
	

   


  	

   


  
	

   


  	

  BOTANICALS

  INTERNATIONAL EXTRACTS, INC.


  
	

   


  	

   


  
	

  By:


  	

  /s/  Kenneth C. Cleveland


  
	

   


  	

  Name:  Kenneth C. Cleveland


  
	

   


  	

  Title:  Chief Executive Officer


  
	

   


  	

   


  



































 








	

   


  	

  ZETAPHARM,

  INC.


  
	

   


  	

   


  
	

  By:


  	

  /s/  Thomas W. Hanlon


  
	

   


  	

  Name:  Thomas W. Hanlon


  
	

   


  	

  Title:  Secretary and Treasurer


  
	

   


  	

   


  










 





























EXHIBIT

A TO COLLATERAL ASSIGNMENT




ISSUED U.S. PATENTS




	

  Title


  	

   


  	

  Patent No.


  	

   


  	

  Grant Date


  	

   


  
	

  OXIDATION

  PRODUCTS OF CEPHALOMANNINE


  	

   


  	

  5,336,684


  	

   


  	

  8/9/1994


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  ELECTROPLATING

  OF SUPERCONDUCTOR ELEMENTS


  	

   


  	

  5,470,820


  	

   


  	

  11/28/1995


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  ELECTROPLATING

  OF SUPERCONDUCTOR ELEMENTS


  	

   


  	

  5,244,875


  	

   


  	

  9/14/1993


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  OXIDATION OF

  GLYCOSIDE SUBSTITUTED TAXANES TO TAXOL OR TAXOL PRECURSORS AND NEW TAXANE

  COMPOUNDS FORMED AS INTERMEDIATES


  	

   


  	

  5,412,116


  	

   


  	

  5/2/1995


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  OXIDATION OF

  CEPHALOMANNINE WITH OZONE IN THE PRESENCE OF TAXOL


  	

   


  	

  5,334.732


  	

   


  	

  8/2/1994


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  PROCESS FOR

  SEPARATING CEPHALOMANNINE FROM TAXOL USING OZONE AND WATER-SOLUBLE HYDRAZINES

  OR HYDRAZIDES


  	

   


  	

  5,364,947


  	

   


  	

  11/15/1994


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  GIRARD

  DERIVATIVES OF TAXANES (AS AMENDED)


  	

   


  	

  5,792,877


  	

   


  	

  8/11/1998


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  PREPARATION OF

  10-DEACETYLBACATIN III AND 7-PROTECTED-10-DEACETYLBACCATIN III DERIVATIVES

  FROM 10-DEACETYLETAXOL A, 10-DEACETYL TAXOL B, AND 10-DEACETYL TAXOL


  	

   


  	

  5,449, 790


  	

   


  	

  9/12/1995


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  CEPHALOMANNINE

  EXPOXIDE, ITS ANALOGUES A METHOD FOR PREPARING THE SAME


  	

   


  	

  5,892,063


  	

   


  	

  4/6/1999


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  7 —HEXANOL YL T

  AXOL AND METHOD FOR PREPARING THE SAME


  	

   


  	

  6,136,988


  	

   


  	

  10/24/2000


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  SELECTIVE

  PROCESS FOR THE DEACETYLATION OF TAXOL AND TAXANES


  	

   


  	

  5,629,433


  	

   


  	

  5/13/1997


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  PREPARATION OF

  TAXOL AND DOCETAXEL THROUGH PRIMARY AMINES


  	

   


  	

  5,679,807


  	

   


  	

  10/21/1997


  	

   


  





 




 




 





























 




	

  Title


  	

   


  	

  Patent No.


  	

   


  	

  Grant Date


  	

   


  
	

  PREPARATION OF

  TAXOL AND DOCETAXEL THROUGH PRIMARY AMINES


  	

   


  	

  5,808,113


  	

   


  	

  9/15/1998


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  ARTEMISININ

  DIMER COMPOUNDS HAVING ANTICANCER ACTIVITY


  	

   


  	

  5,677,468


  	

   


  	

  10/14/1997


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  ARTEMISININ

  DIMER COMPOUNDS HAVING ANTICANCER ACTIVITY


  	

   


  	

  5,856,351


  	

   


  	

  1/5/1999


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  TRIOXANE DIMER

  COMPOUNDS HAVING ANTI PROLIFERATIVE AND ANTITUMOR ACTIVITIES


  	

   


  	

  6,004,997


  	

   


  	

  12/21/1999


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  STORAGE STABLE,

  CITRUS-FLAVORED COMPOSITIONS COMPRISING PLANT EXTRACTS


  	

   


  	

  6,306,450


  	

   


  	

  10/23/2001


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  C-10

  CARBON-SUBSTITUTED ARTEMISININ-LiKE TRIOXANE COMPOUNDSHAVING ANTIMALARIAL,

  ANTIPROLIFERATIVE AND ANTITUMOR ACTIVITIES


  	

   


  	

  6,156, 790


  	

   


  	

  12/5/2000


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  C-10

  CARBON-SUBSTITUTED ARTEMISININ-LiKE TRIOXANE COMPOUNDSHAVING ANTIMALARIAL,

  ANTI PROLIFERATIVE AND ANTITUMOR ACTIVITIES


  	

   


  	

  6,160,004


  	

   


  	

  12/12/2000


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  ARTEMISININ

  ANALOGS HAVING ANTIMALARIAL, ANTIPROLIFERATIVE,AND ANTITUMOR ACTIVITIES AND

  CHEMOSElECTIVE METHODS OF MAKING THE SAME


  	

   


  	

  6,297,272


  	

   


  	

  1 0/2/2001


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  HIGH MOLECULAR

  WEIGHT PRIMARY ALIPHATIC ALCOHOLS OBTAINED FROM BEESWAX AND PHARMACEUTICAL

  USE THEREOF


  	

   


  	

  6,225,354


  	

   


  	

  5/1/2001


  	

   


  





 




 




A - 2





























ISSUED EUROPEAN PATENTS




	

  Title


  	

   


  	

  Patent No.


  	

   


  	

  Grant Date


  	

   


  
	

  ARTEMISININ

  DIMERS WITH ANTICANCER ACTIVITY


  	

   


  	

  0882037


  	

   


  	

  9/12/2001


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  ARTEMISININ

  DIMERS WITH ANTICANCER ACTIVITY


  	

   


  	

  69615220.7-0


  	

   


  	

  9/12/2001


  	

   


  





 




A - 3





























PENDING INTERNATIONAL PATENT APPLICATIONS




 




	

  Title


  	

   


  	

  Patent No.


  	

   


  	

  Grant Date


  	

   


  
	

  METHOD FOR

  ISOLATION OF CAFFEINE-FREE CATECHINS FROM GREEN TEA


  	

   


  	

  PCT/USOO/00282


  	

   


  	

  2/1/2000


  	

   


  
	

  COMPOSITIONS

  COMPRISING NATURAL AGENTS FOR TREATMENT OF CANCER


  	

   


  	

  PCT/US01/12096


  	

   


  	

  4/13/2001


  	

   


  
	

  COMPOSITIONS

  COMPRISING ICARISIDE I AND ANHYDROICARITIN AND METHODS FOR MAKING THE SAME


  	

   


  	

  PCT/US01/22700


  	

   


  	

  7/19/2001


  	

   


  
	

  EFFICIENT METHOD

  FOR PRODUCING COMPOSITIONS ENRICHED IN ANTHOCYANINS


  	

   


  	

  PCT/US01/27107


  	

   


  	

  8/30/2001


  	

   


  





 




A - 4





























PENDING JAPANESE PATENT APPLICATIONS




 




	

  Title


  	

   


  	

  Patent No.


  	

   


  	

  Grant Date


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  OXIDATION

  PRODUCTS OF CEPHALOMANNINE


  	

   


  	

  524451/94


  	

   


  	

  4/25/1994


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  OXIDATION OF

  GLYCOSIDE SUBSTITUTED TAXANES TO TAXOLORTAXOLPRECURSORS AND NEW TAXANE

  COMPOUNDS FORMED AS INTERMEDIATES


  	

   


  	

  512190/94


  	

   


  	

  11/2/1993


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  CEPHALOMANNINE

  EXPOXIDE, ITS ANALOGUES METHOD FOR PREPARING THE SAME


  	

   


  	

  8-527756


  	

   


  	

  3/8/1996


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  7-HEXANOL YL

  TAXOL AND METHODS FOR PREPARING THE SAME


  	

   


  	

  2000-543447


  	

   


  	

  4/9/1999


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  PREPARATION OF

  TAXOL AND DOCETAXEL THROUGH PRIMARY AMINES


  	

   


  	

  8-523705


  	

   


  	

  1/30/1996


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  TRIOXANE DIMERS

  HAVING ANTIPROLIFERATIVE AND ANTITUMOR ACTIVITIES


  	

   


  	

  10-525676


  	

   


  	

  12/1/1997


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  STORAGE STABLE,

  CITRUS-FLAVORED COMPOSITIONS COMPRISING PLANT EXTRACTS


  	

   


  	

  11-504963


  	

   


  	

  6/23/1998


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  C-10

  CARBON-SUBSTITUTED ARTEMISININ-LiKE TRIOXANE COMPOUNDSHA VING ANTIMALARIAL,

  ANTI PROLIFERATIVE AND ANTITUMOR ACTIVITIES


  	

   


  	

  PCT/US98/27717


  	

   


  	

  12/30/1998


  	

   


  





 




A - 5





























PENDING OTHER FOREIGN PATENT APPLICATIONS




 




	

  Title


  	

   


  	

  Patent No.


  	

   


  	

  Grant Date


  	

   


  
	

  OXIDATION

  PRODUCTS OF CEPHALOMANNINE


  	

   


  	

  2,161,138


  	

   


  	

  4/25/1994


  	

   


  
	

  OXIDATION OF

  GLYCOSIDE SUBSTITUTED TAXANES TO TAXOL OR TAXOL PRECURSORS AND NEW TAXANE

  COMPOUNDS FORMED AS INTERMEDIATES


  	

   


  	

  2,148,943


  	

   


  	

  11/2/1993


  	

   


  
	

  CEPHALOMANNINE

  EXPOXIDE, ITS ANALOGUES METHOD FOR PREPARING THE SAME


  	

   


  	

  2,214,993


  	

   


  	

  3/8/1996


  	

   


  
	

  7-HEXANOL YL

  TAXOL AND METHODS FOR PREPARING THE SAME


  	

   


  	

  34888/99


  	

   


  	

  4/9/1999


  	

   


  
	

  7-HEXANOL YL

  TAXOL AND METHODS FOR PREPARING THE SAME


  	

   


  	

  2,327,791


  	

   


  	

  4/9/1999


  	

   


  
	

  PREPARATION OF

  TAXOL AND DOCETAXEL THROUGH PRIMARY AMINES


  	

   


  	

  2,211,799


  	

   


  	

  1/30/1996


  	

   


  
	

  ARTEMISININ

  DIMER COMPOUNDS HAVING ANTICANCER ACTIVITY


  	

   


  	

  2,234,731


  	

   


  	

  6/27/1996


  	

   


  
	

  TRIOXANE DIMERS

  HAVING ANTI PROLIFERATIVE AND ANTITUMOR ACTIVITIES


  	

   


  	

  2,273,374


  	

   


  	

  12/1/1997


  	

   


  
	

  STORAGE STABLE,

  CITRUS-FLAVORED COMPOSITIONS COMPRISING PLANT EXTRACTS


  	

   


  	

  2,294,458


  	

   


  	

  6/23/1998


  	

   


  
	

  C-10

  CARBON-SUBSTITUTED ARTEMISININ-LIKE TRIOXANE COMPOUNDSHAVING ANTIMALARIAL,

  ANTI PROLIFERATIVE AND ANTITUMOUR ACTIVITIES


  	

   


  	

  20184/99


  	

   


  	

  12/30/1998


  	

   


  
	

  C-10

  CARBON-SUBSTITUTED ARTEMISININ-LIKE TRIOXANE COMPOUNDSHAVING ANTIMALARIAL,

  ANTI PROLIFERATIVE AND ANTITUMOR ACTIVITIES


  	

   


  	

  2,317,112


  	

   


  	

  12/30/1998


  	

   


  
	

  ARTEMISININ

  ANALOGS HAVING ANTIMALARIAL, ANTIPROLIFERATIVE,AND ANTITUMOR ACTIVITIES AND

  CHEMOSELECTIVE METHODS OF MAKING THE SAME


  	

   


  	

  27239/00


  	

   


  	

  1/11/2000


  	

   


  





 




A - 6





























 




	

  ARTEMISININ

  ANALOGS HAVING ANTIMALARIAL, ANTIPROLIFERATIVE,AND ANTITUMOR ACTIVITIES AND

  CHEMOSELECTIVE METHODS OF MAKING THE SAME


  	

   


  	

  XXXXXX


  	

   


  	

  1/11/2000


  	

   


  





 




A - 7





























ISSUED OTHER FOREIGN PATENTS




 




	

  Title


  	

   


  	

  Patent No.


  	

   


  	

  Grant Date


  	

   


  
	

  OXIDATION

  PRODUCTS OF CEPHALOMANNINE


  	

   


  	

  685119


  	

   


  	

  4/30/1998


  	

   


  
	

  PREPARATION OF

  TAXOL AND DOCETAXEL THROUGH PRIMARY AMINES


  	

   


  	

  694,627


  	

   


  	

  11/5/1998


  	

   


  
	

  ARTEMISININ

  DIMER COMPOUNDS HAVING ANTICANCER ACTIVITY


  	

   


  	

  725724


  	

   


  	

  10/19/2000


  	

   


  
	

  TRIOXANE DIMERS

  HAVING ANTIPROLIFERATIVE AND ANTITUMOR ACTIVITIES


  	

   


  	

  730722


  	

   


  	

  6/28/2001


  	

   


  





 




A - 8





























PENDING U.S. PATENT APPLICATIONS




 




	

  Title


  	

   


  	

  Patent No.


  	

   


  	

  Grant Date


  	

   


  
	

  PROCESS OF

  CONVERTING OXO-10-DAXT INTO 10-DEACETYL BACCATIN III (CIP)


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  PROCESS OF

  CONVERTING BACCATIN III INTO 10-DEACETYL BACCATIN III


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  7-HEXANOYL TAXOL

  AND METHOD FOR PREPARING THE SAME


  	

   


  	

  09/688,753


  	

   


  	

  10/16/2000


  	

   


  
	

  TRIOXANE DIMERS

  HAVING ANTI PROLIFERATIVE AND ANTITUMOR ACTIVITIES


  	

   


  	

  09/717,815


  	

   


  	

  11/21/2000


  	

   


  
	

  STORAGE STABLE,

  CITRUS-FLAVORED COMPOSITIONS COMPRISING PLANT EXTRACTS


  	

   


  	

  not yet assigned


  	

   


  	

  10/19/2001


  	

   


  
	

  HIGH PURITY

  BETA-CAROTENE AND PROCESS FOR OBTAINING SAME


  	

   


  	

  08/864,103


  	

   


  	

  5/28/1997


  	

   


  
	

  ARTEMISININ

  ANALOGS HAVING ANTIMALARIAL, ANTIPROLIFERATIVE,AND ANTITUMOR ACTIVITIES AND

  CHEMOSELECTIVE METHODS OF MAKING THE SAME


  	

   


  	

  09/887,922


  	

   


  	

  6/22/2001


  	

   


  
	

  COMPOSITIONS

  COMPRISING NATURAL AGENTS FOR TREATMENT OF CANCER


  	

   


  	

  09/550,436


  	

   


  	

  4/17/2000


  	

   


  
	

  COMPOSITIONS

  COMPRISING ICARISIDE I AND ANHYDROICARITIN ANDMETHODS FOR MAKING THE SAME


  	

   


  	

  09/638,367


  	

   


  	

  8/15/2000


  	

   


  
	

  EFFICIENT METHOD

  FOR PRODUCING COMPOSITIONS ENRICHED IN ANTHOCYANINS


  	

   


  	

  09/943, 158


  	

   


  	

  8/30/2001


  	

   


  
	

  HIGH MOLECULAR

  WEIGHT PRIMARY ALIPHATIC ALCOHOLS OBTAINED FROM NATURAL PRODUCTS AND USES

  THEREOF


  	

   


  	

  09/845,043


  	

   


  	

  4/27/2001


  	

   


  
	

  HIGH MOLECULAR

  WEIGHT PRIMARY ALIPHATIC ALCOHOLS OBTAINED FROM NATURAL PRODUCTS AND USES

  THEREOF


  	

   


  	

  09/949,285


  	

   


  	

  9/7/2001


  	

   


  





 




A - 9





























PENDING EUROPEAN PATENT

APPLICATIONS




	

  Title


  	

   


  	

  Patent No.


  	

   


  	

  Grant Date


  	

   


  
	

  OXIDATION OF

  GLYCOSIDE SUBSTITUTED TAXANES TO TAXOL ORTAXOL PRECURSORS AND NEW TAXANE

  COMPOUNDS FORMED AS INTERMEDIATES


  	

   


  	

  94900515.1


  	

   


  	

  11/2/1993


  	

   


  
	

  7 —HEXANOL YL T

  AXOL AND METHODS FOR PREPARING THE SAME


  	

   


  	

  99916599.6


  	

   


  	

  4/9/1999


  	

   


  
	

  PREPARATION OF

  TAXOL AND DOCETAXEL THROUGH PRIMARY AMINES


  	

   


  	

  96907021.8


  	

   


  	

  1/30/1996


  	

   


  
	

  TRIOXANE DIMERS

  HAVING ANTI PROLIFERATIVE AND ANTITUMOR ACTIVITIES


  	

   


  	

  97949655.1


  	

   


  	

  12/1/1997


  	

   


  
	

  STORAGE STABLE,

  CITRUS-FLAVORED COMPOSITIONS COMPRISING PLANT EXTRACTS


  	

   


  	

  98929112.5


  	

   


  	

  6/23/1998


  	

   


  
	

  C-10

  CARBON-SUBSTITUTED ARTEMISININ-LIKE TRIOXANE COMPOUNDSHA VING ANTIMALARIAL,

  ANTI PROLIFERATIVE AND ANTITUMOR ACTIVITIES


  	

   


  	

  98964977.7


  	

   


  	

  12/30/1998


  	

   


  
	

  PROCESS FOR

  REMOVING IMPURITIES FROM NATURAL PRODUCT EXTRACTS


  	

   


  	

  99956616.9-


  	

   


  	

  10/20/1999


  	

   


  
	

  ARTEMISININ

  ANALOGS HAVING ANTIMALARIAL, ANTIPROLIFERATIVE,AND ANTITUMOR ACTIVITIES AND

  CHEMOSElECTIVE METHODS OF MAKING THE SAME


  	

   


  	

  00905584.9


  	

   


  	

  1/11/2000


  	

   


  





 




A - 10





























REGISTERED TRADEMARKS




	

  European

  Union


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  Mark


  	

   


  	

  Number


  	

   


  	

  Registration

  Date


  	

   


  
	

  NATURAL RATIO

  (Classes: 05)


  	

   


  	

  001417674


  	

   


  	

  02/14/01


  	

   


  





 




PENDING TRADEMARKS




	

  United

  States


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  Mark


  	

   


  	

  Number


  	

   


  	

  Filing Date


  	

   


  
	

  APISOL (Classes:

  05)


  	

   


  	

  76-193748


  	

   


  	

  01/12/01


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  BIOENHANCE

  (Classes: 05)


  	

   


  	

  76-193420


  	

   


  	

  01/12/01


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  INVIGORA

  (Classes: 05)


  	

   


  	

  76-089302


  	

   


  	

  07/14/00


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  NATURAL RATIO

  (Classes: 05)


  	

   


  	

  75-726748


  	

   


  	

  06/11/99


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  NATURAL RATIO

  (Classes: 42)


  	

   


  	

  75-726749


  	

   


  	

  06/11/99


  	

   


  
	

   


  	

   


  	

   


  	

   


  	

   


  	

   


  
	

  PREVENTIA

  (Classes: 05)


  	

   


  	

  76-089329


  	

   


  	

  07/14/00


  	

   


  





 




NYC1 #431294 v1




 




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