Heads of Agreement



 Exhibit 10.29 
 CONFIDENTIAL TREATMENT REQUESTED 
 Portions of this Exhibit have been redacted
pursuant to a request for confidential treatment under Rule 24b-2 of the General Rules and Regulations under the Securities Exchange Act of 1934, as amended. Such redacted portions have been replaced with “[***]” in
this Exhibit. An unredacted version of this document has been filed separately with the Securities and Exchange Commission along with the request for confidential treatment 
 CONFIDENTIAL INFORMATION OF GENMARK AND ADVANCED LIQUID LOGIC, INC. 
 Heads of
Agreement 
 Clinical Micro Sensors, Inc. d/b/a GenMark Diagnostics, Inc. (“GenMark”) 

and Advanced Liquid Logic, Inc. (“ALL”) 
 March 30, 2012 
  

			
		
	 1.      Definitions
	  	
		
	 a.      Licensed IP
	  	All intellectual property owned or controlled by ALL, including patents and know-how, necessary or useful to make, have made, use, sell, offer for sale, or import Licensed Products
in the Field.
		
	 b.      Licensed Product
	  	Any product for use in Diagnostic Testing, including instruments and consumables, the manufacture, use, sale, offer for sale, or importation of which, would (but for a license from
ALL) infringe a valid patent claim of the Licensed IP.
		
	 c.      Territory
	  	Worldwide
		
	 d.      Field
	  	Protein Analyte Field and Molecular Analyte Field, and subject to exercise of the option described in 2c below, the Other Analyte Field.
		
	 (i)     Protein Analyte Field
	  	Human in-vitro Diagnostic testing using Genmark e-Detection of protein and/or peptide analytes.
		
	 (ii)    Molecular Analyte Field
	  	Human in-vitro Diagnostic testing using Electrochemical Detection of DNA, RNA or other nucleotide sequence analytes, excluding detection utilizing Sequencing (to be
defined).
		
	 (iii)  Other Analyte Field
	  	Human in-vitro Diagnostic testing using Genmark e-Detection of analytes other than: (i) proteins and/or peptides and (ii) DNA, RNA or other nucleotide sequences.
		
	 e.      Electrochemical Detection
	  	Use of at least two electrodes to apply potential and measure current produced by a chemical reaction occurring in a liquid in contact with the electrodes. For the sake of clarity,
Electrochemical Detection excludes detection methods which involve detection or measurement of conductivity, impedance or capacitance of a droplet, a portion of a droplet, or the contents of a droplet, as well as electrochemilimenescence and optical
means of detection.
		
	 f.       GenMark e-Detection
	  	Detection of an analyte based on a Complex where the Electrochemical Label is detected using Electrochemical Detection.
		
	 g.      Complex
	  	Complex comprising a capture ligand coupled to an electrode surface, a target analyte, and an Electrochemical Label
		
	 h.      Electrochemical Label
	  	Moieties that function in a Complex to produce an electrical signal (detected by the electrode) by oxidation or reduction of the moiety, including metal complexes of iron,
ruthenium, and osmium. For the sake of clarity, Electrochemical Label specifically excludes enzymatic labels (except as provided in the nonexclusive license granted in 2.c.) and labels that function by releasing hydrogen ions.
		
	 i.       Diagnostic
	  	Testing for the purpose of diagnosis, prognosis, monitoring, screening or predicting a disease or condition in a human, or selecting a therapeutic or prophylactic regimen; excluding
screening of newborn infants for metabolic or other disorders in fields other than in the Molecular Analyte Field using GenMark e-Detection.


  
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 CONFIDENTIAL INFORMATION OF GENMARK AND ADVANCED LIQUID LOGIC, INC. 

 


			
		
	 j.       Collaboration Inventions
	  	All inventions and know-how (whether or not patentable) that are first invented (as that term is defined under U.S. Patent Laws) as a direct result of activities undertaken under
the Development Plan, including activities performed by a third party on a party’s behalf.
		
	 k.      Other Terms
	  	Capitalized terms not defined herein will be defined in the Definitive Agreements.
		
	 2.      Licenses
	  	The following licenses will be granted only upon execution of the Definitive Agreements:
		
	 a.      GenMark e-Detection Technology
	  	Exclusive license, under the Licensed IP, to make, have made, use, sell, offer for sale, and import for use in the Protein Analyte Field and Molecular Analyte Field those Licensed
Products utilizing GenMark e-Detection in the Territory.
		
	 b.      [***] Molecular Diagnostics
	  	Exclusive license, under the Licensed IP, to make, have made, use, sell, offer for sale, and import for use in the Molecular Analyte Field those Licensed Products utilizing
Electrochemical Detection [***] in the Territory.
		
	 c.      Enzyme Labels
	  	Nonexclusive license, under the Licensed IP, to make, have made, use, sell, offer for sale, and import for use in the Protein Analyte Field those Licensed Products utilizing
Electrochemical Detection [***] in the Territory where the Electrochemical Label is an enzyme.
		
	 d.      Option for Other Analyte Field
	  	GenMark shall have the option to obtain an exclusive license, under the Licensed IP, to make, have made, use, sell, offer for sale, and import for use in the Other Analyte Field
those Licensed Products utilizing GenMark e-Detection in the Territory. Such option shall be exercisable at any time within [***] ([***]) years of the effective date of the Definitive Agreements upon (i) the payment by GenMark of $[***] and (ii) the
agreement to pay a one-time $[***] milestone payment upon reaching $[***] of net sales of consumable Licensed Products for use in the Other Analyte Field.
		
	 3.      Right of First Refusal
	  	Following execution of the Definitive Agreements:
		
	 a.      [***] Molecular Diagnostics
	  	ALL grants GenMark a one-year right of first refusal to obtain a right or license under the Licensed IP in the Molecular Analyte Field for products using Electrochemical Detection
[***].
		
	 b.      Other In-Vitro Diagnostics
	  	For a period of [***] years, ALL will notify GenMark prior to licensing a third party for products in human in-vitro Diagnostic testing using Electrochemical Detection for targets
outside the Protein Analyte Field and the Molecular Analyte Field, excluding detection utilizing Sequencing (to be defined).
		
	 4.      Payments
	  	
		
	 a.      Equity Investment
	  	 •   $[***] shares of ALL preferred stock at signing of the Definitive Agreements (as defined below), subject
to due diligence, terms and a price to be agreed


  

	[***]	Information has been omitted and filed separately with the Securities and Exchange Commission. Confidential Treatment has been requested with respect to the omitted
portions. 


  
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 CONFIDENTIAL INFORMATION OF GENMARK AND ADVANCED LIQUID LOGIC, INC. 

 


			
		
		  	 •   Rights to participate in future financing

 
 •   Terms of the equity
investment will be substantially equivalent to ALL’s series E, or if no series E has been issued, ALL’s series D, and will include an anti-dilution feature whereby GenMark will be awarded (at no cost to GenMark) more shares if there is a
subsequent financing at lower per-share price than the per-share price paid by GenMark.

		
	 b.      Cash Payments
	  	
		
	 (i)      Initial Payment
	  	$[***] at signing of the Definitive Agreements
		
	 (ii)     Milestone Driven Non-Equity Payments
	  	$[***] based on development milestones to be agreed, payments to be spread across the development period
		
	 5.      Royalties on Instrument Licensed Products
	  	
		
		  	[***]% of net capital sales of instrument Licensed Products
		
	 a.      Revenue Sharing
	  	The Definitive Agreements will include provisions protecting against shifting of sales revenue from Licensed Products to non-royalty bearing products.
		
	 6.      Product Development
	  	Following execution of the Definitive Agreements:
		
	 a.      Management
	  	A Joint Development Committee (“JDC”), consisting of representatives from GenMark and ALL, will be formed for the purpose of monitoring progress of under the Development
Plan (as defined below), and coordinate resources and efforts.
		
	 b.      Development Plan
	  	ALL shall perform certain activities supporting the development of Licensed Products utilizing ALL’s proprietary electrowetting according to a “Development Plan.” An
initial Development Plan will be appended to the Definitive Agreement and will describe the activities to be undertaken by ALL, and the timelines and budget therefor.
		
	 c.      Fees
	  	ALL’s activities under the Development Plan will be funded by GenMark, including reimbursement of ALL’s direct costs and indirect costs for such activities, which costs
shall be consistent with ALL’s auditable, DCAA approved rate structure.
		
	 7.      Component Supply
	  	Following execution of the Definitive Agreements:
		
		  	 •    Subject to agreed to terms regarding the continuity and quality of supply, ALL shall be the
exclusive supplier of the components of consumable Licensed Products that incorporate ALL’s proprietary electro-wetting technology. The price of each component of a consumable Licensed Product supplied over a given period will equal to the sum
of [***].


  

	[***]	Information has been omitted and filed separately with the Securities and Exchange Commission. Confidential Treatment has been requested with respect to the omitted
portions. 


  
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 CONFIDENTIAL INFORMATION OF GENMARK AND ADVANCED LIQUID LOGIC, INC. 

 


			
		
		  	The price of the each component of a consumable Licensed Product supplied by ALL shall be subject to volume-based caps to be negotiated and based on the benchmarking of comparable
raw material and labor costs at such volumes.
		
	 8.      IP Ownership
	  	Following execution of the Definitive Agreements:
		
		  	 Collaboration Inventions shall be treated as follows: (i) ALL shall, subject to the rights and licenses granted to GenMark, solely own
all ALL Inventions; (ii) GenMark shall solely own all GenMark Inventions; and (iii) all inventions, other than ALL Inventions and GenMark Inventions shall be jointly owned by the parties.

 
 GenMark Inventions are those Collaboration Inventions that relate solely to
Electrochemical Detection and Collaboration Inventions that are apparatus that relate solely to Electrochemical Detection.
  
 ALL Inventions are those Collaboration Inventions that relate solely to digital microfluidics (to be defined).

		
	 9.      Other Terms
	  	
		
		  	The Definitive Agreements will include other customary terms and conditions contained in similar agreements of the type. These will include, for example, diligence requirements,
co-branding of products, confidentiality, auditing rights, representations and warranties, dispute resolution, and termination.
		
	 10.    Binding Nature
	  	
		
		  	ALL and GenMark shall enter into one or more agreements reflecting the terms and conditions set forth in this Heads of Agreement and other terms mutually agreeable to the parties
(“Definitive Agreements”). ALL and GenMark agree to negotiate diligently and in good faith to prepare and execute such Definitive Agreements as soon as practicable. Pending execution of the Definitive Agreements, this Heads of Agreement
shall be deemed a legally binding obligation of the parties hereto. Upon termination of this Heads of Agreement as provided for in Section 11 (Effective Date), all provisions of this Heads of Agreement will be null and void, and except for the
provisions of Section 15 (Confidentiality), no provision of this Heads of Agreement shall survive expiration or termination.
		
	 11.    Effective Date
	  	
		
		  	 This Heads of Agreement shall commence on the Effective Date (as defined below), and shall terminate upon the earlier of:

 
 (A)     execution
by the parties of the Definitive Agreements;
  
 (B)     agreement by the parties in writing; or
  

(C)     failure to obtain [***] written consent for ALL to enter into the Definitive
Agreements prior to the expiration of the Negotiation Period (as defined below).


  

	[***]	Information has been omitted and filed separately with the Securities and Exchange Commission. Confidential Treatment has been requested with respect to the omitted
portions. 


  
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 CONFIDENTIAL INFORMATION OF GENMARK AND ADVANCED LIQUID LOGIC, INC. 

 


			
		
	 12.    Representations & Warranties
	  	
		
		  	 Each party hereby represents and warrants that, as of the Effective Date, it has the full right and authority, and has obtained all
approvals, permits or consents necessary, to enter into this Heads of Agreement, and to perform all of its obligations hereunder.
  

ALL has not, prior to the date hereof, entered into and shall not, following the date hereof and prior to the expiration of this Heads of Agreement, enter
into any agreement and has not granted any now existing, or agreed to grant any future, license, right or privilege which agreement, license, right or privilege conflicts in any way with this Heads of Agreement, the rights and licenses granted to
GenMark hereunder, or ALL’s obligations hereunder.
  
 Notwithstanding
the terms of this Section 12, GenMark acknowledges that it will be necessary for ALL to obtain written consent from [***] prior to completion of the Definitive Agreements. ALL represents and warrants that is will use its best efforts to obtain any
and all consents from [***] required to enter into the Definitive Agreements within thirty (30) days of the Effective Date.

		
	 13.    Miscellaneous
	  	
		
		  	This Heads of Agreement shall be governed by and construed under the laws of the State of Delaware, without regard to the conflict of laws provisions thereof. This Heads of
Agreement may be executed in one or more counterparts, each of which shall constitute one and the same Agreement. For purposes of executing this agreement, a facsimile copy of this Heads of Agreement, including the signature pages, will be deemed an
original. This Heads of Agreement has been prepared jointly and no rule of strict construction shall be applied against either party. In this Heads of Agreement, the singular shall include the plural and vice versa and the word “including”
shall be deemed to be followed by the phrase “without limitation.” The section headings contained in this Agreement are inserted for convenience only and shall not affect in any way the meaning or interpretation of this Heads of
Agreement.
		
	 14.    Arbitration
	  	
		
		  	If, despite the diligent and good faith efforts of the parties, for a period of at least one hundred eighty (180) days from the Effective Date (“Negotiation Period”), the
parties are unable to prepare and execute the Definitive Agreements reflecting the terms and conditions set forth in this Heads of Agreement, then either party may submit the matter to final and binding arbitration under the auspices of the American
Arbitration Association (“AAA”). Unless otherwise agreed to by the parties, any such arbitration shall be conducted in San Diego, California pursuant to the then-current commercial arbitration rules of the AAA, as modified herein. Such
arbitration shall be conducted in the English language. The arbitration tribunal shall consist of a single arbitrator who is an independent expert in worldwide business development in the diagnostics industry, mutually acceptable to the parties. If
the parties are unable to agree on an arbitrator, the arbitrator shall be an independent expert as described in the preceding sentence selected by the chief executive of the San Diego office of the
AAA.

  

	[***]	Information has been omitted and filed separately with the Securities and Exchange Commission. Confidential Treatment has been requested with respect to the omitted
portions. 


  
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		  	 Any such arbitration hereunder shall be a “baseball” type arbitration. Accordingly, notwithstanding the commercial arbitration
rules of the AAA, each party shall provide to the arbitrator, and the other party, its proposed version of the Definitive Agreements. Each party may submit a revised version of its proposed Definitive Agreements to the arbitrator and the other party
within thirty (30) days after receiving the other party’s initial proposal. If so requested by the arbitrator, each party shall make oral submissions to the arbitrator based on such party’s proposal; provided that other party shall have
the right to be present during any such oral submissions. The arbitrator shall select one party’s proposed Definitive Agreements as his or her decision, and shall not have the authority to render any substantive decision other than to select
the proposal submitted by either GenMark or ALL (as initially submitted, or as revised in accordance with the foregoing, as applicable). The parties shall use diligent efforts to complete any arbitration within sixty (60) days following a request by
a party for such arbitration.
  
 The administrative charges,
arbitrator’s fees, and related expenses of any arbitration shall be shared equally by the parties, but each party shall be responsible for its own expenses in connection with such arbitration (including its own attorneys’ fees).

 
 The decision of the arbitrator shall be the binding remedy between the parties
regarding the dispute presented to the arbitrator. Any decision of the arbitrator may be entered in a court of competent jurisdiction for judicial recognition of the decision and an order of enforcement.

Pending the selection of the arbitrator or pending the arbitrator’s determination of the merits of any arbitration, either party may seek appropriate
interim or provisional relief from any court of competent jurisdiction as necessary to protect the rights or property of that party.

		
	 15.    Confidentiality
	  	
		
		  	During the course of this Heads of Agreement, the parties may receive from each other information which is proprietary and confidential to the party disclosing such information.
Such information, as well as the existence of and terms of this Heads of Agreement, shall be deemed “Proprietary Information” as that term is used in the Mutual Confidentiality Agreement between the parties and effective June 30, 2010
(“Mutual CDA”), and shall be subject to the terms and provisions of the Mutual CDA. Further, the Purpose of the Mutual CDA is hereby amended to include the exchange of information relevant to the this Heads of Agreement, negotiation of the
Definitive Agreements, and the business relationships contemplated thereby.

 * * * * * 
  

	[***]	Information has been omitted and filed separately with the Securities and Exchange Commission. Confidential Treatment has been requested with respect to the omitted
portions. 


  
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 CONFIDENTIAL INFORMATION OF GENMARK AND ADVANCED LIQUID LOGIC, INC. 

 

 IN WITNESS WHEREOF, the parties have caused this Heads of Agreement to be executed
by their duly authorized representatives as of this 30th
day of March, 2012 (“Effective Date”). 

 



			
	Clinical Micro Sensors, Inc.
		
	By:	 	 /s/ Hany Massarany



			
	Name:	 	 Hany Massarany



			
	Title:	 	 President and CEO


 


			
	Advanced Liquid Logic, Inc.
		
	By:	 	 /s/ Richard M. West



			
	Name:	 	 Richard M. West



			
	Title:	 	 President and CEO


 
 


  
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