UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

OFFICE OF CHEMICAL SAFETY AND 

POLLUTION PREVENTION 

MEMORANDUM 

Date: April 2, 2013 

SUBJECT: Trifluralin: Acute, Chronic, and Cancer Aggregate Dietary (Food and Drinking 

Water) Exposure and Risk Assessments for the Section 3 Registration Action on 

Oilseed Crop Group 20. 

PC Code: 036101 

Decision No.: 463234 

Petition No.: NA 

DP Barcode: D41 0618 

Registration No.: NA 

Regulatory Action: Section 3 Registration 

Risk Assessment Type: Dietary CaseNo.: NA 

TXR No.: NA CAS No.: 1582-09-8 

MRIDNo.: NA 40 CFR: §180.207 

FROM: 

THROUGH: 

TO: 

Sheila 

Risk Asses

Piper, 

sment 

emist Branch ~~~ VI 

Health Effects Division (7509P) 

Julie L. Van Alstine, PH,_E vir~_»e~th -*i""~ VCVV!..:A-0~ Thurston G. Morton, Chemtst /~q ;;:?'x;Y~~-----_ Dietary Exposure Science Advisory Council (DESAC) 

Feleci:;:rt, Branch Chief ~ce~c/-~ Risk Assessment Branch VI, HED (7509P) 

Andrew Ertman, Risk Manager Reviewer 

Barbara Madden, Risk Manager 

Registration Division (7505C) 

Executive Summary 

Acute, chronic, and cancer aggregate dietary (food and drinking water) exposure and risk 

assessments for the herbicide trifluralin were conducted using the Dietary Exposure Evaluation 

Model software with the Food Commodity Intake Database (DEEM-FCID) Version 3.16. This 

Page I of27 
Trinuralin Dietary Exposure and Risk Assessment DP Number: 410618 

software uses 2003-2008 food consumption data from the U.S. Department of Agriculture's 

(USDA's) National Health and Nutrition Examination Survey, What We Eat in America, 

(NHANESIWWEIA). The analyses were conducted in support of a human health risk 

assessment for the proposed Section 3 request to add the remaining crops for an Oilseed Crop 

Group 20. This memorandum was reviewed by two peer reviewers of the DESAC per the current 

DESAC Standard Operating Procedure (SOP). 

Acute Dietary Exposure Assessment 

An unrefined, acute dietary exposure assessment using tolerance levels, default DEEM 

processing factors, and assuming 100% crop treated (CT) for the proposed commodities was 

conducted for various population subgroups . . The estimated drinking water concentration of 

trifluralin was provided by the Environmental Fate and Effects Division (EFED) and 

incorporated directly into the acute assessment. The estimated drinking water concentration 

(EDWC) for trifluralin and its major degradates (TR-4, TR-6 and TR-15) was based on the use 

of trifluralin on LA sugarcane. The acute drinking water concentration in surface water is 23 .83 

ppb. 

There were no appropriate toxicological effects attributable to a single exposure (dose) for the 

general population or any other population subgroups except females 13-49 years old; therefore, 

these population subgroups were not included in this assessment. For food and drinking water, 

the acute dietary risk estimate is below HED' s level of concern ( < 100% of the acute population 

adjusted dose (aPAD)) at the 95th percentile of exposure. The acute dietary exposure estimate for 

females 13-49 years old is less than 1% of the aPAD. 

Chronic Dietary Exposure Assessment 

The chronic dietary exposure and risk estimates are somewhat refined since they assume 

tolerance levels, %CT data, and DEEM default processing factors. Pesticide Data Program 

(PDP) monitoring data were used for carrot, orange, orange juice, pepper, potato, and tomato 

which had a significant impact on the cancer exposure. The chronic EDWC in surface water for 

trifluralin is 1.97 ppb. 

Combined chronic dietary exposure estimates for food and drinking water are well below HED's 

level of concern. Using the DEEM-FCID software, dietary exposure is less than 1% for the U.S. 

population and all infants the most highly exposed population subgroup. 

Cancer Dietary Exposure Assessment 

The Agency classified trifluralin as a Group C- "possible" human carcinogen. The Q1 *is 2.96 X 

10·3 (mglkg/day):

1 The cancer chronic EDWC in surface water for trifluralin is 1.59 ppb. For 

food and drinking water, the cancer dietary exposure estimate for the U.S. population is 2.1 xl0- 7 

I. Introduction 

Page 2 of27 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 3 of 27

I. Introduction

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide. For acute 

and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose 

(i.e., the dose that HED has concluded will result in no unreasonable adverse health effects). 

This dose is referred to as the population adjusted dose (PAD). The PAD is equivalent to the 

point of departure (POD, NOAEL, LOAEL, e.g.) divided by the required uncertainty or safety 

factors.

For acute and non-cancer chronic exposures, HED is concerned when estimated dietary risk 

exceeds 100% of the PAD. References that discuss the acute and chronic risk assessments in 

more detail are available on the EPA/pesticides web site: “Available Information on Assessing 

Exposure from Pesticides, A User’s Guide,” 21-JUN-2000, web link: 

http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf; or see SOP 99.6 (20-AUG1999).

The most recent dietary risk assessment for trifluralin was conducted by S. Piper (08/10/2004, 

D296628).

II. Residue Information

Trifluralin is a selective, pre-emergence, dinitroaniline herbicide registered for the control of 

annual grasses and certain broadleaf weeds. Tolerances for residues of trifluralin (α,α, αtrifluoro-2,6-dinitro-N. N-dipropyl-p-toluidine) in/on plant and processed commodities are 

currently expressed in terms of the residues of trifluralin. Permanent tolerances are established 

for plant commodities under 40 CFR §180.207 and tolerances range from 0.05 ppm to 2.0 ppm.

The residue of concern for both the tolerance expression and risk assessment in plants is 

trifluralin. No livestock tolerances have been established.

IR-4 is requesting permanent tolerances for trifluralin use on Oilseed CG 20. Tolerances at 0.05 

ppm for canola/rapeseed, seeds of flax, mustard, sunflower, safflower, and cottonseed have 

already been established. The proposed use pattern for all members of the rapeseed subgroup 

20A, sunflower subgroup 20B, and cottonseed subgroup 20C, has the same use pattern; 

therefore, HED is recommending a tolerance of 0.05 ppm for CG 20.

Residue Data used for the Acute Dietary Assessment:

An unrefined, acute dietary exposure assessment using tolerance levels, default DEEM 

processing factors (except for orange juice and tomato paste used PDP data) , and assuming 

100% CT for the proposed commodities.
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 4 of 27

Residue Data used for the Chronic and Cancer Dietary Assessment:

The chronic dietary exposure and risk estimates are somewhat refined since they assume 

tolerance levels, %CT, and DEEM default processing factors. PDP monitoring data were used 

for carrot, orange, orange juice, pepper, potato, and tomato which had a significant impact on the 

cancer exposure. See table 1 below for calculations.

Table 1: Trifluralin Summary of Data and Residue Estimates Used for Chronic Dietary Exposure

Analysis

Commodity Data Source No. of 

Samples

No. of 

Detects

1⁄2 LOD

(ppm)

% Crop 

Treated

(avg.)

Anticipated 

Residues 

(Chronic/Cancer) 

Carrots PDP data 

2006-07

1487 796 0.0085 40 0.022

Orange PDP data 

2009-10

1488 0 0.015 1 0.015

Orange Juice PDP data 

2010

191 0 0.0005 1 0.0005

Pepper PDP 2010 277 0 0.001 25 0.001

Potato PDP data 

2009-08

1488 4 0.0085 2.5 0.009

Tomato PDP data 

2008-07

1481 0 0.01 60 0.01

Tomato Paste PDP data 

2010

742 0 0.0475 60 0.0475

III. Percent Crop Treated Information

The Biological and Economic Analysis Division (BEAD) has provided an updated Screening 

Level Usage Analysis (SLUA) for trifluralin (D406856, J. Alsadek, 12/12/2012) which includes 

both an average and maximum PCT for the established uses. 

For the acute dietary exposure assessment, 100%CT was assumed for all commodities. The 

following average percent crop treated estimates were used in the chronic and cancer dietary risk 

assessments for the following crops that are currently registered for trifluralin: almonds: 1%; 

asparagus: 20%; barley: 1%; green bean: 25%; broccoli: 10%; cabbage: 40%; canola: 2.5%; 

cantaloupe: 25%; carrot: 40%; cauliflower: 10%; celery: 12.5%; corn: 1%; cotton: 30%; 

cucumber: 2.5%; dry bean/pea: 10%; garlic: 5%; grapefruit: 1%; grape: 2.5%; honeydew: 20%; 

lemon: 1%; onion: 2.5%; orange: 1%; peach: 1%; peanut: 5%; pecan: 1%; pepper: 25%; 

pistachio: 2.5%; potato: 2.5%; pumpkin: 5%; sorghum: 1%; soybean: 5%; squash: 5%; 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 5 of 27

sugarbeet: 2.5%; sugarcane: 5%; sunflower: 10%; tomato: 60%; walnut: 1%; watermelon: 10%; 

and wheat: 1%. See Attachment 7.

IV. Drinking Water Data

References: Drinking Water Assessment to Establish Tolerances of Parent Trifluralin and its 

Degradates for Oilseed Crop Group 20, D401006, Faruque Khan, 07/02/2012.

A screening level drinking water assessment was conducted to support the human health risk 

assessment to expand canola/rapeseed, sunflower seed and cottonseed tolerances of trifluralin 

herbicide to include oilseed CG 20. This is an abbreviated drinking water assessment to provide 

EDWC of trifluralin and its major degradates in surface water and ground water in support of 

human health risk assessment. The assessment is based on drinking water assessment previously 

performed for the Tolerance Reassessment Eligibility Decision (TRED) (D296624, December 3, 

2003). The EDWCs for oilseed crops are based on the maximum proposed application rates for 

aerial and ground applications specified in the proposed product labels (Treflan®HFP, and 

Treflan®TR-10). Water residues were incorporated in the DEEM-FCID into the food categories 

“water, direct, all sources” and “water, indirect, all sources.” 

The EECs for trifluralin and its major degradates TR-4 (α,α,α -trifluoro-5-nitro-N4,N4-dipropyltoluene-3,4-diamine), TR-6 (5-trifluoromethyl-3-nitro-1,2-benzenediamine) and TR-15 (2-ethyl7-nitro-5-(trifluoromethyl) benzimidazole) are the residues of concern in drinking water. The 

EDWCs of total toxic trifluralin residue for various crops were generated with the coupled 

models PRZM and EXAMS for surface water and SCI-GROW for ground water. The upperbound EDWCs for trifluralin and its major degradates are provided in Table 2 for the human 

health risk assessment.

The most conservative estimates were obtained from aerial application of trifluralin to LA 

sugarcane as a surrogate scenario for Hawaii at the maximum labeled annual application rate of 4 

lbs a.i./acre, applied twice annually at 2 lbs a.i./acre. The updated EDWCs for sugarcane are 

lower than the previously reported EDWCs in the TRED (U.S. EPA 2003) due to two 

applications at 2.0 lbs a.i./A as prescribed in current labels instead of 1 application at 4.0 lbs/A 

per year used in the previous assessment. Based on the results of current modeling, EFED 

recommends an acute EDWC of 23.83μg/L, a chronic EDWC of 1.97μg/L, and a cancer chronic 

EDWC of 1.59μg/L for surface water be used in the human health risk assessment. The model 

and its description are available at the EPA internet site:

http://www.epa.gov/oppefed1/models/water/.

Table 2. Estimated Drinking Water Concentrations (EDWCs) of Trifluralin and its 

Degradates for Surface Water using PRZM/EXAMS and Groundwater using SCIGROW 

Drinking Water 

Source (model)

Use

Scenario

(modeled rate)

1-in-10 year acute

(μg/L)

1-in-10 year chronic

(μg/L)

30- year average 

(μg/L)

Surface Water 

(PRZM/EXAMS)

Sugarcane:

FL Sugarcane STD

(2 app. X 1.0 lbs ai/acre)

3.89 (A)10.74(A) 0.59(A)
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 6 of 27

Table 2. Estimated Drinking Water Concentrations (EDWCs) of Trifluralin and its 

Degradates for Surface Water using PRZM/EXAMS and Groundwater using SCIGROW 

Drinking Water 

Source (model)

Use

Scenario

(modeled rate)

1-in-10 year acute

(μg/L)

1-in-10 year chronic

(μg/L)

30- year average 

(μg/L)

Sugarcane:

LA Sugarcane STD (2 app. 

X 1.0 lbs ai/acre)

LA Sugercane STD 2 app. 

X 2.0 lbs ai/acre)

2

11.92(A)

23.83 (A)3

19.37 (G) 4

0.99(A)

1.97(A) 3

1.76 (G) 4

0.80(A)

1.59(A) 3

1.35 (G) 4

Oilseed:

CA Cotton STD 

1app. X 2.0 lbs ai/acre)

3

12.82 (A) 0.35 (A) 0.33 (A)

Oilseed:

MS Cotton STD 

1 app. X 2.0 lbs ai/acre)

3

21.35 (A) 1.08 (A) 0.84 (A)

Oilseed:

NC Cotton STD

1 app. X 2.0 lbs ai/acre)

3

19.63 (A) 0.99 (A) 0.88 (A)

Oilseed:

ND Canola STD

1app. X 1.25 lbs ai/acre)

3

8.16 (A) 0.30 (A) 0.25 (A)

Groundwater 

(SCI-GROW)

For sugarcane

(2 app. X 2.0lbs a.i./acre)

Cottonseed

1 app. X 2.0 lbs/Acre

Oil Seed

1 app. X 1.25 lbs a.i./acre

2.75E-025

1.37E-02

8.58 E-03

2.75-025

1.37E-02

8.58 E-03

2.75E-025

1.37E-02

8.58 E-03

1

= Aerial application

2

= LA Sugarcane STD scenario was used as a surrogate scenario to calculate EDWCs for trifluralin uses in Hawaii

3

= Bolded EDWCs are recommended exposure values for surface water sources for human health risk assessment

4

= Ground application. Exposure from ground application of trifluralin is compared with aerial application for the 

highest exposure scenario (LA Sugarcane STD) for sugarcane at 4.0.lbs/a.i./A.

5

= Groundwater EDWC can be used for acute, chronic and cancer chronic concerns

V. DEEM-FCID Program and Consumption Information

Trifluralin acute, chronic, and cancer dietary exposure assessments were conducted using the 

DEEM-FCID, Version 3.16, which incorporates 2003-2008 consumption data from USDA’s 

NHANES/WWEIA. The data are based on the reported consumption of more than 20,000 

individuals over two non-consecutive survey days. Foods “as consumed” (e.g., apple pie) are 

linked to EPA-defined food commodities (e.g., apples, peeled fruit - cooked; fresh or N/S; baked; 

or wheat flour - cooked; fresh or N/S, baked) using publicly available recipe translation files 

developed jointly by USDA/ARS and EPA. For chronic exposure assessment, consumption data 

are averaged for the entire U.S. population and within population subgroups. However, for acute 

exposure assessment, consumption data are retained as individual consumption events. Based on 

analysis of the 2003-2008 WWEIA consumption data, which took into account dietary patterns 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 7 of 27

and survey respondents, HED concluded that it is most appropriate to report risk for the 

following population subgroups: the general U.S. population, all infants (<1 year old), children 

1-2, children 3-5, children 6-12, youth 13-19, adults 20-49, females 13-49, and adults 50-99

years old.

For a chronic dietary exposure assessment, an estimate of the residue level in each food or foodform (e.g., orange or orange juice) on the food commodity residue list is multiplied by the 

average daily consumption estimate for that food/food form to produce a residue intake estimate. 

The resulting residue intake estimate for each food/food form is summed with the residue intake 

estimates for all other food/food forms on the commodity residue list to arrive at the total 

average estimated exposure. Exposure is expressed in mg/kg body weight/day and as a percent 

of the cPAD. This procedure is performed for each population subgroup.

For an acute exposure assessment, individual one-day food consumption data are used on an 

individual-by-individual basis. The reported consumption amounts of each food item can be 

multiplied by a residue point estimate and summed to obtain a total daily pesticide exposure for a 

deterministic exposure assessment, or “matched” in multiple random pairings with residue values 

and then summed in a probabilistic assessment. The resulting distribution of exposures is 

expressed as a percentage of the aPAD on both a user (i.e., only those who reported eating 

relevant commodities/food forms) and a per-capita (i.e., those who reported eating the relevant 

commodities as well as those who did not) basis. In accordance with HED policy, per capita 

exposure and risk are reported for analyses performed at all levels of refinement. However, for 

deterministic assessments, any significant differences in user vs. per capita exposure and risk are 

specifically identified and noted in the risk assessment.

VI. Toxicological Information

HED evaluated the toxicology database for trifluralin and selected the following doses and 

endpoints for the dietary risk assessment (Hazard Identification Assessment Review Committee04/17/2003). The Q1

*

of 5.79 X 10-3(mg/kg/day)-1 was updated to 2.96 x 10-3(mg/kg/day)-1in 

2004 based on the Fischer 344 Rat Dietary 3⁄4’s scaling factor (May 11, 2004, TXR No. 

0052534) and is still based on the incidence of male rat thyroid follicular cell combined 

adenoma, papillary adenoma, cystadenoma, and carcinoma tumors. It has been classified as a 

Group C (“Possible” Human Carcinogen). Table 3 provides a summary of the toxicological 

doses and endpoints for trifluralin for use in the dietary exposure assessment. 

Table 3: Summary of Toxicological Points of Departure and Endpoints for Trifluralin for Use in 

Dietary Human Health Risk Assessments

Exposure/

Scenario

Point of 

Departure

Uncertainty 

Factors

Level of Concern for 

Risk Assessment Study and Toxicological Effects

Acute Dietary

(Females 13-50 

years of age)

NOAEL = 100 

mg/kg/day

UFA=10x

UFH=10x

FQPA SF 

=1 

100 mg/kg/day NOAEL 

 100 (UF)

aRfD = 1.0 mg/kg/day 

Developmental Toxicity Study – Rat

LOAEL = 500 mg/kg/day, based 

on increased total litter 

resorptions
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 8 of 27

Table 3: Summary of Toxicological Points of Departure and Endpoints for Trifluralin for Use in 

Dietary Human Health Risk Assessments

Acute Dietary

(General 

population, 

including infants 

and children)

No endpoints identified from the available developments toxicity studies (rat and rabbit) appropriate for 

an acute dietary assessment for trifluralin.

Chronic Dietary

(All populations)

NOAEL = 

2.4 mg/kg/day

UFA=10x

UFH=10x

FQPA SF 

=1 

 2.4mg/kg/day NOAEL 

 100 (UF)

cRfD = 0.024 mg/kg/day 

Chronic (capsule) Toxicity – Dog

LOAEL = 40 mg/kg/day, based on 

increased frequency of abnormal 

stool, decreased body weights and 

body weight gains, and decreased 

erythrocytes and hemoglobin and 

increased thrombocytes (males)

Cancer (oral, 

dermal, inhalation)

Classification: Group C (“Possible” Human Carcinogen)

Q 1 

* = 2.96 X 10-3 (mg/kg/day)-1 (TXR No. 00052534) 

1 Explanation of Abbreviations: Point of Departure (PoD) = A data point or an estimated point that is 

derived from observed dose-response data and used to mark the beginning of extrapolation to determine 

risk associated with lower environmentally relevant human exposures. NOAEL = no observed adverse 

effect level. LOAEL = lowest observed adverse effect level. UF = uncertainty factor. UFA = extrapolation 

from animal to human (interspecies). UFA = extrapolation from animal to human (interspecies). UFH = 

potential variation in sensitivity among members of the human population (intraspecies). UFDB = database 

uncertainty, lack of neurotoxicity (acute and subchronic) and immunotoxicity studies, 

VII. Results/Discussion 

As stated above, for acute and chronic assessments, HED is concerned when dietary risk exceeds 

100% of the PAD. The DEEM-FCID analyses estimate the dietary exposure of the U.S. 

population and various population subgroups. The results reported in Table 4 are for the general 

U.S. Population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 13-19, 

females 13-49, adults 20-49, and adults 50-99 years. Cancer risk is determined for the general 

U.S. population only.

Acute Dietary Exposure Analysis

There were no appropriate toxicological effects attributable to a single exposure (dose) for the 

general population or any other population subgroups except females 13-49 years old; therefore,

these population subgroups were not included in this assessment. For food and drinking water, 

the acute dietary risk estimate is below HED’s level of concern (<100% of the aPAD) at the 95th

percentile of exposure. The acute dietary exposure estimate for females 13-49 years old is less 

than 1% of the aPAD.
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 9 of 27

Chronic Dietary Exposure Analysis

Combined chronic dietary exposure estimates for food and drinking water are well below HED’s 

level of concern. Using the DEEM-FCID software, dietary exposure is less than 1% for the U.S. 

population and all infants, the most highly exposed population subgroup.

Cancer Dietary Exposure Analysis

The Agency classified trifluralin as a Group C- “possible” human carcinogen. The Q1

*

is 2.96 X 

10-3(mg/kg/day).

-1

 The cancer chronic EDWC in surface water for trifluralin is 1.59 ppb. For 

food and drinking water, the cancer dietary exposure estimate for the U.S. population is 2.1 x10-

7

.

Table 4. Summary of Dietary (Food and Drinking Water) Exposure and Risk for Trifluralin

Population Subgroup

Acute Dietary

(95th Percentile) Chronic Dietary Cancer

Dietary 

Exposure 

(mg/kg/day)

% 

aPAD

Dietary 

Exposure

(mg/kg/day)

% 

cPAD

Dietary 

Exposure

(mg/kg/day)

Risk

General U.S. Population

N/A

0.000078 <1 0.000070 2.1E-07

All Infants (<1 year old) 0.000213 <1

N/A N/A

Children 1-2 years old 0.000158 <1

Children 3-5 years old 0.000128 <1

Children 6-12 years old 0.000082 <1

Youth 13-19 years old 0.000055 <1

Adults 20-49 years old 0.000070 <1

Adults 50-99 years old 0.000074 <1

Females 13-49 years old 0.002305 <1 0.000070 <1

VIII. Characterization of Inputs/Outputs

The assumptions made in this acute assessment are conservative; tolerance level residues and 

assuming 100% crop treated. For chronic and cancer assessments, monitoring data (PDP) and 

percent crop treated were used for carrots, orange, orange juice, pepper, potato, and tomato since 

they had a significant impact on exposure. More highly refined analyses are not needed at this 

time since the risk estimates are below HED’s level of concern.

IX. Conclusions

This somewhat refine analysis demonstrates that the requested uses for trifluralin will not result 

in an acute, chronic and cancer dietary risk estimates that exceed HED’s level of concern for any 

of the regulated populated subgroups, including those comprised of infants and children. 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 10 of 27

X. List of Attachments

Attachment 1: Acute Food plus Water Residue Input File

Attachment 2: Acute Results File

Attachment 3: Chronic Food plus Water Residue Input File

Attachment 4: Chronic Results File

Attachment 5: Cancer Food plus Water Residue Input File

Attachment 6: Cancer Results File

Attachment 7: Trifluralin Screening Level Usage Analysis (SLUA)

Attachment 1: Acute Food plus Water Residue Input File

Filename: C:\Documents and 

Settings\spiper\Desktop\Trifluralin\Dietary\Trifluralin_acute_tolerance.r08

Chemical: Trifluralin

RfD(Chronic): .024 mg/kg bw/day NOEL(Chronic): 2.4 mg/kg bw/day

RfD(Acute): 1 mg/kg bw/day NOEL(Acute): 100 mg/kg bw/day Q*= .0058

Date created/last modified: 01-31-2013/11:52:33 Program ver. 3.16, 03-08-d

Comment: Females 13-50 yrs only (acute)

-----------------------------------------------------------------------------------

 EPA Crop Def Res Adj.Factors Comment

 Code Grp Commodity Name (ppm) #1 #2 

---------- ---- ------------------------------- ---------- ------ ------ -------

9500019000 O Asparagus 0.050000 1.000 1.000 

9500177000 O Grape, leaves 0.050000 1.000 1.000 

9500178000 O Grape, raisin 0.050000 4.300 1.000 

9500188000 O Hop 0.050000 1.000 1.000 

9500263000 O Peanut 0.050000 1.000 1.000 

9500264000 O Peanut, butter 0.050000 1.890 1.000 

9500265000 O Peanut, oil 0.050000 1.000 1.000 

9500275000 O Peppermint 0.050000 1.000 1.000 

9500276000 O Peppermint, oil 2.000000 1.000 1.000 

9500352000 O Spearmint 0.050000 1.000 1.000 

9500353000 O Spearmint, oil 2.000000 1.000 1.000 

9500363000 O Sugarcane, molasses 0.050000 1.000 1.000 

9500363001 O Sugarcane, molasses-babyfood 0.050000 1.000 1.000 

9500362000 O Sugarcane, sugar 0.050000 1.000 1.000 

9500362001 O Sugarcane, sugar-babyfood 0.050000 1.000 1.000 

0103015000 1CD Arrowroot, flour 0.050000 1.000 1.000 

0103015001 1CD Arrowroot, flour-babyfood 0.050000 1.000 1.000 

0103017000 1CD Artichoke, Jerusalem 0.050000 1.000 1.000 

0101050000 1AB Beet, garden, roots 0.050000 1.000 1.000 

0101050001 1AB Beet, garden, roots-babyfood 0.050000 1.000 1.000 

0101052000 1A Beet, sugar 0.050000 1.000 1.000 

0101053000 1A Beet, sugar, molasses 0.050000 1.000 1.000 

0101053001 1A Beet, sugar, molasses-babyfood 0.050000 1.000 1.000 

0101052001 1A Beet, sugar-babyfood 0.050000 1.000 1.000 

0101067000 1AB Burdock 0.050000 1.000 1.000 

0101078000 1AB Carrot 1.000000 1.000 1.000 

0101079000 1AB Carrot, juice 1.000000 1.000 1.000 

0101078001 1AB Carrot-babyfood 1.000000 1.000 1.000 

0103082000 1CD Cassava 0.050000 1.000 1.000 

0103082001 1CD Cassava-babyfood 0.050000 1.000 1.000 

0101084000 1AB Celeriac 0.050000 1.000 1.000 

0101100000 1AB Chicory, roots 0.050000 1.000 1.000 

0103139000 1CD Dasheen, corm 0.050000 1.000 1.000 

0103166000 1CD Ginger 0.050000 1.000 1.000 

0103167000 1CD Ginger, dried 0.050000 1.000 1.000 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 11 of 27

0103166001 1CD Ginger-babyfood 0.050000 1.000 1.000 

0101168000 1AB Ginseng, dried 0.050000 1.000 1.000 

0101190000 1AB Horseradish 0.050000 1.000 1.000 

0101250000 1AB Parsley, turnip rooted 0.050000 1.000 1.000 

0101251000 1AB Parsnip 0.050000 1.000 1.000 

0101251001 1AB Parsnip-babyfood 0.050000 1.000 1.000 

0103296000 1C Potato, chips 0.050000 1.000 1.000 

0103297000 1C Potato, dry (granules/ flakes) 0.050000 6.500 1.000 

0103297001 1C Potato, dry (granules/ flakes)-b 0.050000 6.500 1.000 

0103298000 1C Potato, flour 0.050000 1.000 1.000 

0103298001 1C Potato, flour-babyfood 0.050000 1.000 1.000 

0103300000 1C Potato, tuber, w/o peel 0.050000 1.000 1.000 

0103300001 1C Potato, tuber, w/o peel-babyfood 0.050000 1.000 1.000 

0103299000 1C Potato, tuber, w/peel 0.050000 1.000 1.000 

0103299001 1C Potato, tuber, w/peel-babyfood 0.050000 1.000 1.000 

0101316000 1AB Radish, Oriental, roots 0.050000 1.000 1.000 

0101314000 1AB Radish, roots 0.050000 1.000 1.000 

0101327000 1AB Rutabaga 0.050000 1.000 1.000 

0101331000 1AB Salsify, roots 0.050000 1.000 1.000 

0103366000 1CD Sweet potato 0.050000 1.000 1.000 

0103366001 1CD Sweet potato-babyfood 0.050000 1.000 1.000 

0103371000 1CD Tanier, corm 0.050000 1.000 1.000 

0103387000 1CD Turmeric 0.050000 1.000 1.000 

0101388000 1AB Turnip, roots 0.050000 1.000 1.000 

0103407000 1CD Yam bean 0.050000 1.000 1.000 

0103406000 1CD Yam, true 0.050000 1.000 1.000 

0200051000 2 Beet, garden, tops 0.050000 1.000 1.000 

0200101000 2 Chicory, tops 0.050000 1.000 1.000 

0200140000 2 Dasheen, leaves 0.050000 1.000 1.000 

0200317000 2 Radish, Oriental, tops 0.050000 1.000 1.000 

0200315000 2 Radish, tops 0.050000 1.000 1.000 

0200332000 2 Salsify, tops 0.050000 1.000 1.000 

0302103000 3B Chive, fresh leaves 0.050000 1.000 1.000 

0301165000 3A Garlic, bulb 0.050000 1.000 1.000 

0301165001 3A Garlic, bulb-babyfood 0.050000 1.000 1.000 

0302198000 3B Leek 0.050000 1.000 1.000 

0301237000 3A Onion, bulb 0.050000 1.000 1.000 

0301238000 3A Onion, bulb, dried 0.050000 9.000 1.000 

0301238001 3A Onion, bulb, dried-babyfood 0.050000 9.000 1.000 

0301237001 3A Onion, bulb-babyfood 0.050000 1.000 1.000 

0302239000 3B Onion, green 0.050000 1.000 1.000 

0301338000 3A Shallot, bulb 0.050000 1.000 1.000 

0302338500 3B Shallot, fresh leaves 0.050000 1.000 1.000 

0402085000 4B Celery 0.050000 1.000 1.000 

0402086000 4B Celery, juice 0.050000 1.000 1.000 

0402085001 4B Celery-babyfood 0.050000 1.000 1.000 

0401150000 4A Endive 0.050000 1.000 1.000 

0501061000 5A Broccoli 0.050000 1.000 1.000 

0502063000 5B Broccoli raab 0.050000 1.000 1.000 

0501062000 5A Broccoli, Chinese 0.050000 1.000 1.000 

0501061001 5A Broccoli-babyfood 0.050000 1.000 1.000 

0501064000 5A Brussels sprouts 0.050000 1.000 1.000 

0501069000 5A Cabbage 0.050000 1.000 1.000 

0502070000 5B Cabbage, Chinese, bok choy 0.050000 1.000 1.000 

0501072000 5A Cabbage, Chinese, mustard 0.050000 1.000 1.000 

0501071000 5A Cabbage, Chinese, napa 0.050000 1.000 1.000 

0501083000 5A Cauliflower 0.050000 1.000 1.000 

0502117000 5B Collards 0.050000 1.000 1.000 

0502194000 5B Kale 0.050000 1.000 1.000 

0501196000 5A Kohlrabi 0.050000 1.000 1.000 

0502229000 5B Mustard greens 0.050000 1.000 1.000 

0502318000 5B Rape greens 0.050000 1.000 1.000 

0502389000 5B Turnip, greens 0.050000 1.000 1.000 

0603035000 6C Bean, great northern, seed 0.050000 1.000 1.000 

0603030000 6C Bean, black, seed 0.050000 1.000 1.000 

0603032000 6C Bean, broad, seed 0.050000 1.000 1.000 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 12 of 27

0602031000 6B Bean, broad, succulent 0.050000 1.000 1.000 

0603034000 6C Bean, cowpea, seed 0.050000 1.000 1.000 

0602033000 6B Bean, cowpea, succulent 0.050000 1.000 1.000 

0603036000 6C Bean, kidney, seed 0.050000 1.000 1.000 

0603038000 6C Bean, lima, seed 0.050000 1.000 1.000 

0602037000 6B Bean, lima, succulent 0.050000 1.000 1.000 

0603039000 6C Bean, mung, seed 0.050000 1.000 1.000 

0603040000 6C Bean, navy, seed 0.050000 1.000 1.000 

0603041000 6C Bean, pink, seed 0.050000 1.000 1.000 

0603042000 6C Bean, pinto, seed 0.050000 1.000 1.000 

0601043000 6A Bean, snap, succulent 0.050000 1.000 1.000 

0601043001 6A Bean, snap, succulent-babyfood 0.050000 1.000 1.000 

0603099000 6C Chickpea, flour 0.050000 1.000 1.000 

0603098000 6C Chickpea, seed 0.050000 1.000 1.000 

0603098001 6C Chickpea, seed-babyfood 0.050000 1.000 1.000 

0603182000 6C Guar, seed 0.050000 1.000 1.000 

0603182001 6C Guar, seed-babyfood 0.050000 1.000 1.000 

0603203000 6C Lentil, seed 0.050000 1.000 1.000 

0603256000 6C Pea, dry 0.050000 1.000 1.000 

0603256001 6C Pea, dry-babyfood 0.050000 1.000 1.000 

0601257000 6A Pea, edible podded, succulent 0.050000 1.000 1.000 

0603258000 6C Pea, pigeon, seed 0.050000 1.000 1.000 

0602259000 6B Pea, pigeon, succulent 0.050000 1.000 1.000 

0602255000 6B Pea, succulent 0.050000 1.000 1.000 

0602255001 6B Pea, succulent-babyfood 0.050000 1.000 1.000 

0603348000 6C Soybean, flour 0.050000 1.000 1.000 

0603348001 6C Soybean, flour-babyfood 0.050000 1.000 1.000 

0600350000 6 Soybean, oil 0.050000 1.000 1.000 

0600350001 6 Soybean, oil-babyfood 0.050000 1.000 1.000 

0600347000 6 Soybean, seed 0.050000 1.000 1.000 

0600349000 6 Soybean, soy milk 0.050000 1.000 1.000 

0600349001 6 Soybean, soy milk-babyfood or in 0.050000 1.000 1.000 

0601349500 6AB Soybean, vegetable 0.050000 1.000 1.000 

0802148000 8BC Eggplant 0.050000 1.000 1.000 

0802234000 8BC Okra 0.050000 1.000 1.000 

0802270000 8B Pepper, bell 0.050000 1.000 1.000 

0802271000 8B Pepper, bell, dried 0.050000 1.000 1.000 

0802271001 8B Pepper, bell, dried-babyfood 0.050000 1.000 1.000 

0802270001 8B Pepper, bell-babyfood 0.050000 1.000 1.000 

0802272000 8BC Pepper, nonbell 0.050000 1.000 1.000 

0802273000 8BC Pepper, nonbell, dried 0.050000 1.000 1.000 

0802272001 8BC Pepper, nonbell-babyfood 0.050000 1.000 1.000 

0801374000 8A Tomatillo 0.050000 1.000 1.000 

0801375000 8A Tomato 0.050000 1.000 1.000 

0801380000 8A Tomato, Tree 0.050000 1.000 1.000 

0801378000 8A Tomato, dried 0.050000 14.300 1.000 

0801378001 8A Tomato, dried-babyfood 0.050000 14.300 1.000 

0801379000 8A Tomato, juice 0.050000 1.500 1.000 

0801376000 8A Tomato, paste 0.050000 5.400 1.000 

0801376001 8A Tomato, paste-babyfood 0.050000 5.400 1.000 

0801377000 8A Tomato, puree 0.050000 3.300 1.000 

0801377001 8A Tomato, puree-babyfood 0.050000 3.300 1.000 

0801375001 8A Tomato-babyfood 0.050000 1.000 1.000 

0902021000 9B Balsam pear 0.050000 1.000 1.000 

0901075000 9A Cantaloupe 0.050000 1.000 1.000 

0902088000 9B Chayote, fruit 0.050000 1.000 1.000 

0902102000 9B Chinese waxgourd 0.050000 1.000 1.000 

0902135000 9B Cucumber 0.050000 1.000 1.000 

0901187000 9A Honeydew melon 0.050000 1.000 1.000 

0902308000 9B Pumpkin 0.050000 1.000 1.000 

0902309000 9B Pumpkin, seed 0.050000 1.000 1.000 

0902356000 9B Squash, summer 0.050000 1.000 1.000 

0902356001 9B Squash, summer-babyfood 0.050000 1.000 1.000 

0902357000 9B Squash, winter 0.050000 1.000 1.000 

0902357001 9B Squash, winter-babyfood 0.050000 1.000 1.000 

0901399000 9A Watermelon 0.050000 1.000 1.000 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 13 of 27

0901400000 9A Watermelon, juice 0.050000 1.000 1.000 

1001106000 10A Citron 0.050000 1.000 1.000 

1001107000 10A Citrus hybrids 0.050000 1.000 1.000 

1001108000 10A Citrus, oil 0.050000 1.000 1.000 

1003180000 10C Grapefruit 0.050000 1.000 1.000 

1003181000 10C Grapefruit, juice 0.050000 2.100 1.000 

1002197000 10B Kumquat 0.050000 1.000 1.000 

1002199000 10B Lemon 0.050000 1.000 1.000 

1002200000 10B Lemon, juice 0.050000 2.000 1.000 

1002200001 10B Lemon, juice-babyfood 0.050000 2.000 1.000 

1002201000 10B Lemon, peel 0.050000 1.000 1.000 

1002206000 10B Lime 0.050000 1.000 1.000 

1002207000 10B Lime, juice 0.050000 2.000 1.000 

1002207001 10B Lime, juice-babyfood 0.050000 2.000 1.000 

1001240000 10A Orange 0.050000 1.000 1.000 

1001241000 10A Orange, juice 0.050000 1.800 1.000 

1001241001 10A Orange, juice-babyfood 0.050000 1.800 1.000 

1001242000 10A Orange, peel 0.050000 1.000 1.000 

1003307000 10C Pummelo 0.050000 1.000 1.000 

1001369000 10A Tangerine 0.050000 1.000 1.000 

1001370000 10A Tangerine, juice 0.050000 2.300 1.000 

1202012000 12B Apricot 0.050000 1.000 1.000 

1202013000 12B Apricot, dried 0.050000 6.000 1.000 

1202014000 12B Apricot, juice 0.050000 1.000 1.000 

1202014001 12B Apricot, juice-babyfood 0.050000 1.000 1.000 

1202012001 12B Apricot-babyfood 0.050000 1.000 1.000 

1201090000 12A Cherry 0.050000 1.000 1.000 

1201091000 12A Cherry, juice 0.050000 1.500 1.000 

1201091001 12A Cherry, juice-babyfood 0.050000 1.500 1.000 

1201090001 12A Cherry-babyfood 0.050000 1.000 1.000 

1202230000 12B Nectarine 0.050000 1.000 1.000 

1202260000 12B Peach 0.050000 1.000 1.000 

1202261000 12B Peach, dried 0.050000 7.000 1.000 

1202261001 12B Peach, dried-babyfood 0.050000 7.000 1.000 

1202262000 12B Peach, juice 0.050000 1.000 1.000 

1202262001 12B Peach, juice-babyfood 0.050000 1.000 1.000 

1202260001 12B Peach-babyfood 0.050000 1.000 1.000 

1203285000 12C Plum 0.050000 1.000 1.000 

1203287000 12C Plum, prune, dried 0.050000 5.000 1.000 

1203287001 12C Plum, prune, dried-babyfood 0.050000 5.000 1.000 

1203286000 12C Plum, prune, fresh 0.050000 1.000 1.000 

1203286001 12C Plum, prune, fresh-babyfood 0.050000 1.000 1.000 

1203288000 12C Plum, prune, juice 0.050000 1.400 1.000 

1203288001 12C Plum, prune, juice-babyfood 0.050000 1.400 1.000 

1203285001 12C Plum-babyfood 0.050000 1.000 1.000 

1304175000 13D Grape 0.050000 1.000 1.000 

1304176000 13D Grape, juice 0.050000 2.100 1.000 

1304176001 13D Grape, juice-babyfood 0.050000 2.100 1.000 

1304179000 13D Grape, wine and sherry 0.050000 1.000 1.000 

1400003000 14 Almond 0.050000 1.000 1.000 

1400004000 14 Almond, oil 0.050000 1.000 1.000 

1400004001 14 Almond, oil-babyfood 0.050000 1.000 1.000 

1400003001 14 Almond-babyfood 0.050000 1.000 1.000 

1400059000 14 Brazil nut 0.050000 1.000 1.000 

1400068000 14 Butternut 0.050000 1.000 1.000 

1400081000 14 Cashew 0.050000 1.000 1.000 

1400092000 14 Chestnut 0.050000 1.000 1.000 

1400155000 14 Hazelnut 0.050000 1.000 1.000 

1400156000 14 Hazelnut, oil 0.050000 1.000 1.000 

1400185000 14 Hickory nut 0.050000 1.000 1.000 

1400213000 14 Macadamia nut 0.050000 1.000 1.000 

1400269000 14 Pecan 0.050000 1.000 1.000 

1400278000 14 Pine nut 0.050000 1.000 1.000 

1400282000 14 Pistachio 0.050000 1.000 1.000 

1400391000 14 Walnut 0.050000 1.000 1.000 

1500027000 15 Barley, bran 0.050000 1.000 1.000 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 14 of 27

1500026000 15 Barley, flour 0.050000 1.000 1.000 

1500026001 15 Barley, flour-babyfood 0.050000 1.000 1.000 

1500025000 15 Barley, pearled barley 0.050000 1.000 1.000 

1500025001 15 Barley, pearled barley-babyfood 0.050000 1.000 1.000 

1500122000 15 Corn, field, bran 0.050000 1.000 1.000 

1500120000 15 Corn, field, flour 0.050000 1.000 1.000 

1500120001 15 Corn, field, flour-babyfood 0.050000 1.000 1.000 

1500121000 15 Corn, field, meal 0.050000 1.000 1.000 

1500121001 15 Corn, field, meal-babyfood 0.050000 1.000 1.000 

1500125000 15 Corn, field, oil 0.050000 1.000 1.000 

1500125001 15 Corn, field, oil-babyfood 0.050000 1.000 1.000 

1500123000 15 Corn, field, starch 0.050000 1.000 1.000 

1500123001 15 Corn, field, starch-babyfood 0.050000 1.000 1.000 

1500124000 15 Corn, field, syrup 0.050000 1.500 1.000 

1500124001 15 Corn, field, syrup-babyfood 0.050000 1.500 1.000 

1500344000 15 Sorghum, grain 0.050000 1.000 1.000 

1500345000 15 Sorghum, syrup 0.050000 1.000 1.000 

1500401000 15 Wheat, grain 0.050000 1.000 1.000 

1500401001 15 Wheat, grain-babyfood 0.050000 1.000 1.000 

2003114001 20C Coconut, oil-babyfood 0.050000 1.000 1.000 

2003128000 20C Cottonseed, oil 0.050000 1.000 1.000 

2003128001 20C Cottonseed, oil-babyfood 0.050000 1.000 1.000 

2001163000 20A Flax seed, oil 0.050000 1.000 1.000 

2001319000 20A Rapeseed, oil 0.050000 1.000 1.000 

2001319001 20A Rapeseed, oil-babyfood 0.050000 1.000 1.000 

2002330000 20B Safflower, oil 0.050000 1.000 1.000 

2002330001 20B Safflower, oil-babyfood 0.050000 1.000 1.000 

2001337000 20A Sesame, oil 0.050000 1.000 1.000 

2001337001 20A Sesame, oil-babyfood 0.050000 1.000 1.000 

2001336000 20A Sesame, seed 0.050000 1.000 1.000 

2001336001 20A Sesame, seed-babyfood 0.050000 1.000 1.000 

2002365000 20B Sunflower, oil 0.050000 1.000 1.000 

2002365001 20B Sunflower, oil-babyfood 0.050000 1.000 1.000 

2002364000 20B Sunflower, seed 0.050000 1.000 1.000 

8601000000 86A Water, direct, all sources 0.023800 1.000 1.000 

8602000000 86B Water, indirect, all sources 0.023800 1.000 1.000 

Attachment 2: Acute Results File

US EPA Ver. 3.16, 03-08-d

DEEM-FCID ACUTE Analysis for TRIFLURALIN NHANES 2003-2008 2-Day

Residue file: Trifluralin_acute_tolerance.r08 Adjustment factor #2 used.

Analysis Date: 01-31-2013/11:54:56 Residue file dated: 01-31-2013/11:52:33

NOEL (Acute) = 100.000000 mg/kg body-wt/day

RAC/FF intake summed over 24 hours

Run Comment: "Females 13-50 yrs only (acute)"

===============================================================================

Summary calculations--per capita:

--- 95th Percentile---- --- 99th Percentile---- ---99.9th Percentile----

Exposure % aRfD MOE Exposure % aRfD MOE Exposure % aRfD MOE 

---------- ------- -------- ---------- ------- -------- ---------- ------- --------

Female 13-50:

 0.002305 0.23 43390 0.003286 0.33 30427 0.005321 0.53 18793 

Attachment 3: Chronic Food plus Water Residue Input File

Filename: C:\Documents and 

Settings\spiper\Desktop\Trifluralin\Dietary\Trifluralin_chronic_refined.r08

Chemical: Trifluralin
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 15 of 27

RfD(Chronic): .024 mg/kg bw/day NOEL(Chronic): 2.4 mg/kg bw/day

RfD(Acute): 1 mg/kg bw/day NOEL(Acute): 100 mg/kg bw/day Q*= .0027

Date created/last modified: 01-31-2013/16:03:07 Program ver. 3.16, 03-08-d

-----------------------------------------------------------------------------------

 EPA Crop Def Res Adj.Factors Comment

 Code Grp Commodity Name (ppm) #1 #2 

---------- ---- ------------------------------- ---------- ------ ------ -------

9500019000 O Asparagus 0.050000 1.000 0.200 

9500177000 O Grape, leaves 0.050000 1.000 0.025 

9500178000 O Grape, raisin 0.050000 4.300 0.025 

9500188000 O Hop 0.050000 1.000 1.000 

9500263000 O Peanut 0.050000 1.000 0.050 

9500264000 O Peanut, butter 0.050000 1.890 0.050 

9500265000 O Peanut, oil 0.050000 1.000 0.050 

9500275000 O Peppermint 0.050000 1.000 1.000 

9500276000 O Peppermint, oil 2.000000 1.000 1.000 

9500352000 O Spearmint 0.050000 1.000 1.000 

9500353000 O Spearmint, oil 2.000000 1.000 1.000 

9500363000 O Sugarcane, molasses 0.050000 1.000 0.050 

9500363001 O Sugarcane, molasses-babyfood 0.050000 1.000 0.050 

9500362000 O Sugarcane, sugar 0.050000 1.000 0.050 

9500362001 O Sugarcane, sugar-babyfood 0.050000 1.000 0.050 

0103015000 1CD Arrowroot, flour 0.050000 1.000 1.000 

0103015001 1CD Arrowroot, flour-babyfood 0.050000 1.000 1.000 

0103017000 1CD Artichoke, Jerusalem 0.050000 1.000 1.000 

0101050000 1AB Beet, garden, roots 0.050000 1.000 1.000 

0101050001 1AB Beet, garden, roots-babyfood 0.050000 1.000 1.000 

0101052000 1A Beet, sugar 0.050000 1.000 0.025 

0101053000 1A Beet, sugar, molasses 0.050000 1.000 0.025 

0101053001 1A Beet, sugar, molasses-babyfood 0.050000 1.000 0.025 

0101052001 1A Beet, sugar-babyfood 0.050000 1.000 0.025 

0101067000 1AB Burdock 0.050000 1.000 1.000 

0101078000 1AB Carrot 0.022000 1.000 0.400 PDP da

 Full comment: PDP data

0101079000 1AB Carrot, juice 0.022000 1.000 0.400 PDP da

 Full comment: PDP data

0101078001 1AB Carrot-babyfood 0.022000 1.000 0.400 PDP da

 Full comment: PDP data

0103082000 1CD Cassava 0.050000 1.000 1.000 

0103082001 1CD Cassava-babyfood 0.050000 1.000 1.000 

0101084000 1AB Celeriac 0.050000 1.000 1.000 

0101100000 1AB Chicory, roots 0.050000 1.000 1.000 

0103139000 1CD Dasheen, corm 0.050000 1.000 1.000 

0103166000 1CD Ginger 0.050000 1.000 1.000 

0103167000 1CD Ginger, dried 0.050000 1.000 1.000 

0103166001 1CD Ginger-babyfood 0.050000 1.000 1.000 

0101168000 1AB Ginseng, dried 0.050000 1.000 1.000 

0101190000 1AB Horseradish 0.050000 1.000 1.000 

0101250000 1AB Parsley, turnip rooted 0.050000 1.000 1.000 

0101251000 1AB Parsnip 0.050000 1.000 1.000 

0101251001 1AB Parsnip-babyfood 0.050000 1.000 1.000 

0103296000 1C Potato, chips 0.009000 1.000 0.025 PDP da

 Full comment: PDP data

0103297000 1C Potato, dry (granules/ flakes) 0.009000 6.500 0.025 PDP da

 Full comment: PDP data

0103297001 1C Potato, dry (granules/ flakes)-b 0.009000 6.500 0.025 PDP da

 Full comment: PDP data

0103298000 1C Potato, flour 0.009000 1.000 0.025 PDP da

 Full comment: PDP data

0103298001 1C Potato, flour-babyfood 0.009000 1.000 0.025 PDP da

 Full comment: PDP data

0103300000 1C Potato, tuber, w/o peel 0.009000 1.000 0.025 PDP da

 Full comment: PDP data

0103300001 1C Potato, tuber, w/o peel-babyfood 0.009000 1.000 0.025 PDP da

 Full comment: PDP data

0103299000 1C Potato, tuber, w/peel 0.009000 1.000 0.025 PDP da
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 16 of 27

 Full comment: PDP data

0103299001 1C Potato, tuber, w/peel-babyfood 0.009000 1.000 0.025 PDP da

 Full comment: PDP data

0101316000 1AB Radish, Oriental, roots 0.050000 1.000 1.000 

0101314000 1AB Radish, roots 0.050000 1.000 1.000 

0101327000 1AB Rutabaga 0.050000 1.000 1.000 

0101331000 1AB Salsify, roots 0.050000 1.000 1.000 

0103366000 1CD Sweet potato 0.050000 1.000 1.000 

0103366001 1CD Sweet potato-babyfood 0.050000 1.000 1.000 

0103371000 1CD Tanier, corm 0.050000 1.000 1.000 

0103387000 1CD Turmeric 0.050000 1.000 1.000 

0101388000 1AB Turnip, roots 0.050000 1.000 1.000 

0103407000 1CD Yam bean 0.050000 1.000 1.000 

0103406000 1CD Yam, true 0.050000 1.000 1.000 

0200051000 2 Beet, garden, tops 0.050000 1.000 1.000 

0200101000 2 Chicory, tops 0.050000 1.000 1.000 

0200140000 2 Dasheen, leaves 0.050000 1.000 1.000 

0200317000 2 Radish, Oriental, tops 0.050000 1.000 1.000 

0200315000 2 Radish, tops 0.050000 1.000 1.000 

0200332000 2 Salsify, tops 0.050000 1.000 1.000 

0302103000 3B Chive, fresh leaves 0.050000 1.000 1.000 

0301165000 3A Garlic, bulb 0.050000 1.000 0.050 

0301165001 3A Garlic, bulb-babyfood 0.050000 1.000 0.050 

0302198000 3B Leek 0.050000 1.000 1.000 

0301237000 3A Onion, bulb 0.050000 1.000 0.025 

0301238000 3A Onion, bulb, dried 0.050000 9.000 0.025 

0301238001 3A Onion, bulb, dried-babyfood 0.050000 9.000 0.025 

0301237001 3A Onion, bulb-babyfood 0.050000 1.000 0.025 

0302239000 3B Onion, green 0.050000 1.000 0.025 

0301338000 3A Shallot, bulb 0.050000 1.000 1.000 

0302338500 3B Shallot, fresh leaves 0.050000 1.000 1.000 

0402085000 4B Celery 0.050000 1.000 0.025 

0402086000 4B Celery, juice 0.050000 1.000 0.025 

0402085001 4B Celery-babyfood 0.050000 1.000 0.025 

0401150000 4A Endive 0.050000 1.000 1.000 

0501061000 5A Broccoli 0.050000 1.000 0.100 

0502063000 5B Broccoli raab 0.050000 1.000 1.000 

0501062000 5A Broccoli, Chinese 0.050000 1.000 1.000 

0501061001 5A Broccoli-babyfood 0.050000 1.000 0.100 

0501064000 5A Brussels sprouts 0.050000 1.000 1.000 

0501069000 5A Cabbage 0.050000 1.000 0.400 

0502070000 5B Cabbage, Chinese, bok choy 0.050000 1.000 1.000 

0501072000 5A Cabbage, Chinese, mustard 0.050000 1.000 1.000 

0501071000 5A Cabbage, Chinese, napa 0.050000 1.000 1.000 

0501083000 5A Cauliflower 0.050000 1.000 0.100 

0502117000 5B Collards 0.050000 1.000 1.000 

0502194000 5B Kale 0.050000 1.000 1.000 

0501196000 5A Kohlrabi 0.050000 1.000 1.000 

0502229000 5B Mustard greens 0.050000 1.000 1.000 

0502318000 5B Rape greens 0.050000 1.000 1.000 

0502389000 5B Turnip, greens 0.050000 1.000 1.000 

0603035000 6C Bean, great northern, seed 0.050000 1.000 0.100 

0603030000 6C Bean, black, seed 0.050000 1.000 0.100 

0603032000 6C Bean, broad, seed 0.050000 1.000 0.100 

0602031000 6B Bean, broad, succulent 0.050000 1.000 0.250 

0603034000 6C Bean, cowpea, seed 0.050000 1.000 0.100 

0602033000 6B Bean, cowpea, succulent 0.050000 1.000 0.250 

0603036000 6C Bean, kidney, seed 0.050000 1.000 0.100 

0603038000 6C Bean, lima, seed 0.050000 1.000 0.100 

0602037000 6B Bean, lima, succulent 0.050000 1.000 0.250 

0603039000 6C Bean, mung, seed 0.050000 1.000 0.100 

0603040000 6C Bean, navy, seed 0.050000 1.000 0.100 

0603041000 6C Bean, pink, seed 0.050000 1.000 0.100 

0603042000 6C Bean, pinto, seed 0.050000 1.000 0.100 

0601043000 6A Bean, snap, succulent 0.050000 1.000 0.250 

0601043001 6A Bean, snap, succulent-babyfood 0.050000 1.000 0.250 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 17 of 27

0603099000 6C Chickpea, flour 0.050000 1.000 1.000 

0603098000 6C Chickpea, seed 0.050000 1.000 1.000 

0603098001 6C Chickpea, seed-babyfood 0.050000 1.000 1.000 

0603182000 6C Guar, seed 0.050000 1.000 1.000 

0603182001 6C Guar, seed-babyfood 0.050000 1.000 1.000 

0603203000 6C Lentil, seed 0.050000 1.000 1.000 

0603256000 6C Pea, dry 0.050000 1.000 0.100 

0603256001 6C Pea, dry-babyfood 0.050000 1.000 0.100 

0601257000 6A Pea, edible podded, succulent 0.050000 1.000 0.100 

0603258000 6C Pea, pigeon, seed 0.050000 1.000 0.100 

0602259000 6B Pea, pigeon, succulent 0.050000 1.000 0.100 

0602255000 6B Pea, succulent 0.050000 1.000 0.100 

0602255001 6B Pea, succulent-babyfood 0.050000 1.000 0.100 

0603348000 6C Soybean, flour 0.050000 1.000 0.050 

0603348001 6C Soybean, flour-babyfood 0.050000 1.000 0.050 

0600350000 6 Soybean, oil 0.050000 1.000 0.050 

0600350001 6 Soybean, oil-babyfood 0.050000 1.000 0.050 

0600347000 6 Soybean, seed 0.050000 1.000 0.050 

0600349000 6 Soybean, soy milk 0.050000 1.000 0.050 

0600349001 6 Soybean, soy milk-babyfood or in 0.050000 1.000 0.050 

0601349500 6AB Soybean, vegetable 0.050000 1.000 0.050 

0802148000 8BC Eggplant 0.050000 1.000 1.000 

0802234000 8BC Okra 0.050000 1.000 1.000 

0802270000 8B Pepper, bell 0.001000 1.000 0.250 PDP da

 Full comment: PDP data

0802271000 8B Pepper, bell, dried 0.001000 1.000 0.250 PDP da

 Full comment: PDP data

0802271001 8B Pepper, bell, dried-babyfood 0.001000 1.000 0.250 PDP da

 Full comment: PDP data

0802270001 8B Pepper, bell-babyfood 0.001000 1.000 0.250 PDP da

 Full comment: PDP data

0802272000 8BC Pepper, nonbell 0.001000 1.000 0.250 PDP da

 Full comment: PDP data

0802273000 8BC Pepper, nonbell, dried 0.001000 1.000 0.250 PDP da

 Full comment: PDP data

0802272001 8BC Pepper, nonbell-babyfood 0.001000 1.000 0.250 PDP da

 Full comment: PDP data

0801374000 8A Tomatillo 0.010000 1.000 0.600 PDP da

 Full comment: PDP data

0801375000 8A Tomato 0.010000 1.000 0.600 PDP da

 Full comment: PDP data

0801380000 8A Tomato, Tree 0.010000 1.000 0.600 PDP da

 Full comment: PDP data

0801378000 8A Tomato, dried 0.010000 14.300 0.600 PDP da

 Full comment: PDP data

0801378001 8A Tomato, dried-babyfood 0.010000 14.300 0.600 PDP da

 Full comment: PDP data

0801379000 8A Tomato, juice 0.010000 1.500 0.600 PDP da

 Full comment: PDP data

0801376000 8A Tomato, paste 0.047500 1.000 0.600 PDP da

 Full comment: PDP data

0801376001 8A Tomato, paste-babyfood 0.047500 1.000 0.600 PDP da

 Full comment: PDP data

0801377000 8A Tomato, puree 0.010000 3.300 0.600 PDP da

 Full comment: PDP data

0801377001 8A Tomato, puree-babyfood 0.010000 3.300 0.600 PDP da

 Full comment: PDP data

0801375001 8A Tomato-babyfood 0.010000 1.000 0.600 PDP da

 Full comment: PDP data

0902021000 9B Balsam pear 0.050000 1.000 1.000 

0901075000 9A Cantaloupe 0.022000 1.000 0.250 PDP da

 Full comment: PDP data

0902088000 9B Chayote, fruit 0.050000 1.000 1.000 

0902102000 9B Chinese waxgourd 0.050000 1.000 1.000 

0902135000 9B Cucumber 0.050000 1.000 0.025 

0901187000 9A Honeydew melon 0.050000 1.000 0.200 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 18 of 27

0902308000 9B Pumpkin 0.050000 1.000 0.050 

0902309000 9B Pumpkin, seed 0.050000 1.000 0.050 

0902356000 9B Squash, summer 0.050000 1.000 0.050 

0902356001 9B Squash, summer-babyfood 0.050000 1.000 0.050 

0902357000 9B Squash, winter 0.050000 1.000 0.050 

0902357001 9B Squash, winter-babyfood 0.050000 1.000 0.050 

0901399000 9A Watermelon 0.050000 1.000 0.100 

0901400000 9A Watermelon, juice 0.050000 1.000 0.100 

1001106000 10A Citron 0.050000 1.000 1.000 

1001107000 10A Citrus hybrids 0.050000 1.000 1.000 

1001108000 10A Citrus, oil 0.050000 1.000 1.000 

1003180000 10C Grapefruit 0.050000 1.000 0.010 

1003181000 10C Grapefruit, juice 0.050000 1.200 0.010 

1002197000 10B Kumquat 0.050000 1.000 1.000 

1002199000 10B Lemon 0.050000 1.000 0.010 

1002200000 10B Lemon, juice 0.050000 2.000 0.010 

1002200001 10B Lemon, juice-babyfood 0.050000 2.000 0.010 

1002201000 10B Lemon, peel 0.050000 1.000 0.010 

1002206000 10B Lime 0.050000 1.000 1.000 

1002207000 10B Lime, juice 0.050000 2.000 1.000 

1002207001 10B Lime, juice-babyfood 0.050000 2.000 1.000 

1001240000 10A Orange 0.015000 1.000 0.010 PDP da

 Full comment: PDP data

1001241000 10A Orange, juice 0.000500 1.000 0.010 PDP da

 Full comment: PDP data

1001241001 10A Orange, juice-babyfood 0.000500 1.000 0.010 PDP da

 Full comment: PDP data

1001242000 10A Orange, peel 0.015000 1.000 0.010 PDP da

 Full comment: PDP data

1003307000 10C Pummelo 0.050000 1.000 1.000 

1001369000 10A Tangerine 0.050000 1.000 1.000 

1001370000 10A Tangerine, juice 0.050000 2.300 1.000 

1202012000 12B Apricot 0.050000 1.000 1.000 

1202013000 12B Apricot, dried 0.050000 6.000 1.000 

1202014000 12B Apricot, juice 0.050000 1.000 1.000 

1202014001 12B Apricot, juice-babyfood 0.050000 1.000 1.000 

1202012001 12B Apricot-babyfood 0.050000 1.000 1.000 

1201090000 12A Cherry 0.050000 1.000 1.000 

1201091000 12A Cherry, juice 0.050000 1.500 1.000 

1201091001 12A Cherry, juice-babyfood 0.050000 1.500 1.000 

1201090001 12A Cherry-babyfood 0.050000 1.000 1.000 

1202230000 12B Nectarine 0.050000 1.000 1.000 

1202260000 12B Peach 0.050000 1.000 0.010 

1202261000 12B Peach, dried 0.050000 7.000 0.010 

1202261001 12B Peach, dried-babyfood 0.050000 7.000 0.010 

1202262000 12B Peach, juice 0.050000 1.000 0.010 

1202262001 12B Peach, juice-babyfood 0.050000 1.000 0.010 

1202260001 12B Peach-babyfood 0.050000 1.000 0.010 

1203285000 12C Plum 0.050000 1.000 1.000 

1203287000 12C Plum, prune, dried 0.050000 5.000 1.000 

1203287001 12C Plum, prune, dried-babyfood 0.050000 5.000 1.000 

1203286000 12C Plum, prune, fresh 0.050000 1.000 1.000 

1203286001 12C Plum, prune, fresh-babyfood 0.050000 1.000 1.000 

1203288000 12C Plum, prune, juice 0.050000 1.400 1.000 

1203288001 12C Plum, prune, juice-babyfood 0.050000 1.400 1.000 

1203285001 12C Plum-babyfood 0.050000 1.000 1.000 

1304175000 13D Grape 0.050000 1.000 0.025 

1304176000 13D Grape, juice 0.050000 1.200 0.025 

1304176001 13D Grape, juice-babyfood 0.050000 1.200 0.025 

1304179000 13D Grape, wine and sherry 0.050000 1.000 0.025 

1400003000 14 Almond 0.050000 1.000 0.010 

1400004000 14 Almond, oil 0.050000 1.000 0.010 

1400004001 14 Almond, oil-babyfood 0.050000 1.000 0.010 

1400003001 14 Almond-babyfood 0.050000 1.000 0.010 

1400059000 14 Brazil nut 0.050000 1.000 1.000 

1400068000 14 Butternut 0.050000 1.000 1.000 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 19 of 27

1400081000 14 Cashew 0.050000 1.000 1.000 

1400092000 14 Chestnut 0.050000 1.000 1.000 

1400155000 14 Hazelnut 0.050000 1.000 1.000 

1400156000 14 Hazelnut, oil 0.050000 1.000 1.000 

1400185000 14 Hickory nut 0.050000 1.000 1.000 

1400213000 14 Macadamia nut 0.050000 1.000 1.000 

1400269000 14 Pecan 0.050000 1.000 0.010 

1400278000 14 Pine nut 0.050000 1.000 1.000 

1400282000 14 Pistachio 0.050000 1.000 0.025 

1400391000 14 Walnut 0.050000 1.000 0.010 

1500027000 15 Barley, bran 0.050000 1.000 0.010 

1500026000 15 Barley, flour 0.050000 1.000 0.010 

1500026001 15 Barley, flour-babyfood 0.050000 1.000 0.010 

1500025000 15 Barley, pearled barley 0.050000 1.000 0.010 

1500025001 15 Barley, pearled barley-babyfood 0.050000 1.000 0.010 

1500122000 15 Corn, field, bran 0.050000 1.000 0.010 

1500120000 15 Corn, field, flour 0.050000 1.000 0.010 

1500120001 15 Corn, field, flour-babyfood 0.050000 1.000 0.010 

1500121000 15 Corn, field, meal 0.050000 1.000 0.010 

1500121001 15 Corn, field, meal-babyfood 0.050000 1.000 0.010 

1500125000 15 Corn, field, oil 0.050000 1.000 0.010 

1500125001 15 Corn, field, oil-babyfood 0.050000 1.000 0.010 

1500123000 15 Corn, field, starch 0.050000 1.000 0.010 

1500123001 15 Corn, field, starch-babyfood 0.050000 1.000 0.010 

1500124000 15 Corn, field, syrup 0.050000 1.500 0.010 

1500124001 15 Corn, field, syrup-babyfood 0.050000 1.500 0.010 

1500344000 15 Sorghum, grain 0.050000 1.000 0.010 

1500345000 15 Sorghum, syrup 0.050000 1.000 0.010 

1500401000 15 Wheat, grain 0.050000 1.000 0.010 

1500401001 15 Wheat, grain-babyfood 0.050000 1.000 0.010 

2003114001 20C Coconut, oil-babyfood 0.050000 1.000 1.000 

2003128000 20C Cottonseed, oil 0.050000 1.000 0.300 

2003128001 20C Cottonseed, oil-babyfood 0.050000 1.000 0.300 

2001163000 20A Flax seed, oil 0.050000 1.000 1.000 

2001319000 20A Rapeseed, oil 0.050000 1.000 0.025 

2001319001 20A Rapeseed, oil-babyfood 0.050000 1.000 0.025 

2002330000 20B Safflower, oil 0.050000 1.000 1.000 

2002330001 20B Safflower, oil-babyfood 0.050000 1.000 1.000 

2001337000 20A Sesame, oil 0.050000 1.000 1.000 

2001337001 20A Sesame, oil-babyfood 0.050000 1.000 1.000 

2001336000 20A Sesame, seed 0.050000 1.000 1.000 

2001336001 20A Sesame, seed-babyfood 0.050000 1.000 1.000 

2002365000 20B Sunflower, oil 0.050000 1.000 0.100 

2002365001 20B Sunflower, oil-babyfood 0.050000 1.000 0.100 

2002364000 20B Sunflower, seed 0.050000 1.000 0.100 

8601000000 86A Water, direct, all sources 0.001970 1.000 1.000 

8602000000 86B Water, indirect, all sources 0.001970 1.000 1.000 

Attachment 4: Chronic Results File

US EPA Ver. 3.16, 03-08-d

DEEM-FCID Chronic analysis for TRIFLURALIN NHANES 2003-2008 2-day

Residue file name: C:\Documents and 

Settings\spiper\Desktop\Trifluralin\Dietary\Trifluralin_chronic_refined.r08

 Adjustment factor #2 used.

Analysis Date 01-31-2013/16:07:33 Residue file dated: 01-31-2013/16:03:07

Reference dose (RfD, Chronic) = .024 mg/kg bw/day

===============================================================================

 Total exposure by population subgroup

-------------------------------------------------------------------------------

 Total Exposure

 -----------------------------------

 Population mg/kg Percent of 

 Subgroup body wt/day Rfd 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 20 of 27

-------------------------------------- ------------- ----------------

Total US Population 0.000078 0.3%

Hispanic 0.000077 0.3%

Non-Hisp-White 0.000078 0.3%

Non-Hisp-Black 0.000071 0.3%

Non-Hisp-Other 0.000093 0.4%

Nursing Infants 0.000115 0.5%

Non-Nursing Infants 0.000257 1.1%

Female 13+ PREG 0.000074 0.3%

Children 1-6 0.000136 0.6%

Children 7-12 0.000077 0.3%

Male 13-19 0.000053 0.2%

Female 13-19/NP 0.000057 0.2%

Male 20+ 0.000067 0.3%

Female 20+/NP 0.000075 0.3%

Seniors 55+ 0.000074 0.3%

All Infants 0.000213 0.9%

Female 13-50 0.000070 0.3%

Children 1-2 0.000158 0.7%

Children 3-5 0.000128 0.5%

Children 6-12 0.000082 0.3%

Youth 13-19 0.000055 0.2%

Adults 20-49 0.000070 0.3%

Adults 50-99 0.000074 0.3%

Female 13-49 0.000070 0.3%

-------------------------------------------------------------------------------

Attachment 3: Cancer Food plus Water Residue Input File

Filename: C:\Documents and 

Settings\spiper\Desktop\Trifluralin\Dietary\Trifluralin_cancer_refined.r08

Chemical: Trifluralin

RfD(Chronic): .024 mg/kg bw/day NOEL(Chronic): 2.4 mg/kg bw/day

RfD(Acute): 1 mg/kg bw/day NOEL(Acute): 100 mg/kg bw/day Q*= .00296

Date created/last modified: 01-31-2013/16:13:57 Program ver. 3.16, 03-08-d

Comment: Cancer

-----------------------------------------------------------------------------------

 EPA Crop Def Res Adj.Factors Comment

 Code Grp Commodity Name (ppm) #1 #2 

---------- ---- ------------------------------- ---------- ------ ------ -------

9500019000 O Asparagus 0.050000 1.000 0.200 

9500177000 O Grape, leaves 0.050000 1.000 0.025 

9500178000 O Grape, raisin 0.050000 4.300 0.025 

9500188000 O Hop 0.050000 1.000 1.000 

9500263000 O Peanut 0.050000 1.000 0.050 

9500264000 O Peanut, butter 0.050000 1.890 0.050 

9500265000 O Peanut, oil 0.050000 1.000 0.050 

9500275000 O Peppermint 0.050000 1.000 1.000 

9500276000 O Peppermint, oil 2.000000 1.000 1.000 

9500352000 O Spearmint 0.050000 1.000 1.000 

9500353000 O Spearmint, oil 2.000000 1.000 1.000 

9500363000 O Sugarcane, molasses 0.050000 1.000 0.050 

9500363001 O Sugarcane, molasses-babyfood 0.050000 1.000 0.050 

9500362000 O Sugarcane, sugar 0.050000 1.000 0.050 

9500362001 O Sugarcane, sugar-babyfood 0.050000 1.000 0.050 

0103015000 1CD Arrowroot, flour 0.050000 1.000 1.000 

0103015001 1CD Arrowroot, flour-babyfood 0.050000 1.000 1.000 

0103017000 1CD Artichoke, Jerusalem 0.050000 1.000 1.000 

0101050000 1AB Beet, garden, roots 0.050000 1.000 1.000 

0101050001 1AB Beet, garden, roots-babyfood 0.050000 1.000 1.000 

0101052000 1A Beet, sugar 0.050000 1.000 0.025 

0101053000 1A Beet, sugar, molasses 0.050000 1.000 0.025 

0101053001 1A Beet, sugar, molasses-babyfood 0.050000 1.000 0.025 

0101052001 1A Beet, sugar-babyfood 0.050000 1.000 0.025 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 21 of 27

0101067000 1AB Burdock 0.050000 1.000 1.000 

0101078000 1AB Carrot 0.022000 1.000 0.400 PDP da

 Full comment: PDP data

0101079000 1AB Carrot, juice 0.022000 1.000 0.400 PDP da

 Full comment: PDP data

0101078001 1AB Carrot-babyfood 0.022000 1.000 0.400 PDP da

 Full comment: PDP data

0103082000 1CD Cassava 0.050000 1.000 1.000 

0103082001 1CD Cassava-babyfood 0.050000 1.000 1.000 

0101084000 1AB Celeriac 0.050000 1.000 1.000 

0101100000 1AB Chicory, roots 0.050000 1.000 1.000 

0103139000 1CD Dasheen, corm 0.050000 1.000 1.000 

0103166000 1CD Ginger 0.050000 1.000 1.000 

0103167000 1CD Ginger, dried 0.050000 1.000 1.000 

0103166001 1CD Ginger-babyfood 0.050000 1.000 1.000 

0101168000 1AB Ginseng, dried 0.050000 1.000 1.000 

0101190000 1AB Horseradish 0.050000 1.000 1.000 

0101250000 1AB Parsley, turnip rooted 0.050000 1.000 1.000 

0101251000 1AB Parsnip 0.050000 1.000 1.000 

0101251001 1AB Parsnip-babyfood 0.050000 1.000 1.000 

0103296000 1C Potato, chips 0.009000 1.000 0.025 PDP da

 Full comment: PDP data

0103297000 1C Potato, dry (granules/ flakes) 0.009000 6.500 0.025 PDP da

 Full comment: PDP data

0103297001 1C Potato, dry (granules/ flakes)-b 0.009000 6.500 0.025 PDP da

 Full comment: PDP data

0103298000 1C Potato, flour 0.009000 1.000 0.025 PDP da

 Full comment: PDP data

0103298001 1C Potato, flour-babyfood 0.009000 1.000 0.025 PDP da

 Full comment: PDP data

0103300000 1C Potato, tuber, w/o peel 0.009000 1.000 0.025 PDP da

 Full comment: PDP data

0103300001 1C Potato, tuber, w/o peel-babyfood 0.009000 1.000 0.025 PDP da

 Full comment: PDP data

0103299000 1C Potato, tuber, w/peel 0.009000 1.000 0.025 PDP da

 Full comment: PDP data

0103299001 1C Potato, tuber, w/peel-babyfood 0.009000 1.000 0.025 PDP da

 Full comment: PDP data

0101316000 1AB Radish, Oriental, roots 0.050000 1.000 1.000 

0101314000 1AB Radish, roots 0.050000 1.000 1.000 

0101327000 1AB Rutabaga 0.050000 1.000 1.000 

0101331000 1AB Salsify, roots 0.050000 1.000 1.000 

0103366000 1CD Sweet potato 0.050000 1.000 1.000 

0103366001 1CD Sweet potato-babyfood 0.050000 1.000 1.000 

0103371000 1CD Tanier, corm 0.050000 1.000 1.000 

0103387000 1CD Turmeric 0.050000 1.000 1.000 

0101388000 1AB Turnip, roots 0.050000 1.000 1.000 

0103407000 1CD Yam bean 0.050000 1.000 1.000 

0103406000 1CD Yam, true 0.050000 1.000 1.000 

0200051000 2 Beet, garden, tops 0.050000 1.000 1.000 

0200101000 2 Chicory, tops 0.050000 1.000 1.000 

0200140000 2 Dasheen, leaves 0.050000 1.000 1.000 

0200317000 2 Radish, Oriental, tops 0.050000 1.000 1.000 

0200315000 2 Radish, tops 0.050000 1.000 1.000 

0200332000 2 Salsify, tops 0.050000 1.000 1.000 

0302103000 3B Chive, fresh leaves 0.050000 1.000 1.000 

0301165000 3A Garlic, bulb 0.050000 1.000 0.050 

0301165001 3A Garlic, bulb-babyfood 0.050000 1.000 0.050 

0302198000 3B Leek 0.050000 1.000 1.000 

0301237000 3A Onion, bulb 0.050000 1.000 0.025 

0301238000 3A Onion, bulb, dried 0.050000 9.000 0.025 

0301238001 3A Onion, bulb, dried-babyfood 0.050000 9.000 0.025 

0301237001 3A Onion, bulb-babyfood 0.050000 1.000 0.025 

0302239000 3B Onion, green 0.050000 1.000 0.025 

0301338000 3A Shallot, bulb 0.050000 1.000 1.000 

0302338500 3B Shallot, fresh leaves 0.050000 1.000 1.000 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 22 of 27

0402085000 4B Celery 0.050000 1.000 0.025 

0402086000 4B Celery, juice 0.050000 1.000 0.025 

0402085001 4B Celery-babyfood 0.050000 1.000 0.025 

0401150000 4A Endive 0.050000 1.000 1.000 

0501061000 5A Broccoli 0.050000 1.000 0.100 

0502063000 5B Broccoli raab 0.050000 1.000 1.000 

0501062000 5A Broccoli, Chinese 0.050000 1.000 1.000 

0501061001 5A Broccoli-babyfood 0.050000 1.000 0.100 

0501064000 5A Brussels sprouts 0.050000 1.000 1.000 

0501069000 5A Cabbage 0.050000 1.000 0.400 

0502070000 5B Cabbage, Chinese, bok choy 0.050000 1.000 1.000 

0501072000 5A Cabbage, Chinese, mustard 0.050000 1.000 1.000 

0501071000 5A Cabbage, Chinese, napa 0.050000 1.000 1.000 

0501083000 5A Cauliflower 0.050000 1.000 0.100 

0502117000 5B Collards 0.050000 1.000 1.000 

0502194000 5B Kale 0.050000 1.000 1.000 

0501196000 5A Kohlrabi 0.050000 1.000 1.000 

0502229000 5B Mustard greens 0.050000 1.000 1.000 

0502318000 5B Rape greens 0.050000 1.000 1.000 

0502389000 5B Turnip, greens 0.050000 1.000 1.000 

0603035000 6C Bean, great northern, seed 0.050000 1.000 0.100 

0603030000 6C Bean, black, seed 0.050000 1.000 0.100 

0603032000 6C Bean, broad, seed 0.050000 1.000 0.100 

0602031000 6B Bean, broad, succulent 0.050000 1.000 0.250 

0603034000 6C Bean, cowpea, seed 0.050000 1.000 0.100 

0602033000 6B Bean, cowpea, succulent 0.050000 1.000 0.250 

0603036000 6C Bean, kidney, seed 0.050000 1.000 0.100 

0603038000 6C Bean, lima, seed 0.050000 1.000 0.100 

0602037000 6B Bean, lima, succulent 0.050000 1.000 0.250 

0603039000 6C Bean, mung, seed 0.050000 1.000 0.100 

0603040000 6C Bean, navy, seed 0.050000 1.000 0.100 

0603041000 6C Bean, pink, seed 0.050000 1.000 0.100 

0603042000 6C Bean, pinto, seed 0.050000 1.000 0.100 

0601043000 6A Bean, snap, succulent 0.050000 1.000 0.250 

0601043001 6A Bean, snap, succulent-babyfood 0.050000 1.000 0.250 

0603099000 6C Chickpea, flour 0.050000 1.000 1.000 

0603098000 6C Chickpea, seed 0.050000 1.000 1.000 

0603098001 6C Chickpea, seed-babyfood 0.050000 1.000 1.000 

0603182000 6C Guar, seed 0.050000 1.000 1.000 

0603182001 6C Guar, seed-babyfood 0.050000 1.000 1.000 

0603203000 6C Lentil, seed 0.050000 1.000 1.000 

0603256000 6C Pea, dry 0.050000 1.000 0.100 

0603256001 6C Pea, dry-babyfood 0.050000 1.000 0.100 

0601257000 6A Pea, edible podded, succulent 0.050000 1.000 0.100 

0603258000 6C Pea, pigeon, seed 0.050000 1.000 0.100 

0602259000 6B Pea, pigeon, succulent 0.050000 1.000 0.100 

0602255000 6B Pea, succulent 0.050000 1.000 0.100 

0602255001 6B Pea, succulent-babyfood 0.050000 1.000 0.100 

0603348000 6C Soybean, flour 0.050000 1.000 0.050 

0603348001 6C Soybean, flour-babyfood 0.050000 1.000 0.050 

0600350000 6 Soybean, oil 0.050000 1.000 0.050 

0600350001 6 Soybean, oil-babyfood 0.050000 1.000 0.050 

0600347000 6 Soybean, seed 0.050000 1.000 0.050 

0600349000 6 Soybean, soy milk 0.050000 1.000 0.050 

0600349001 6 Soybean, soy milk-babyfood or in 0.050000 1.000 0.050 

0601349500 6AB Soybean, vegetable 0.050000 1.000 0.050 

0802148000 8BC Eggplant 0.050000 1.000 1.000 

0802234000 8BC Okra 0.050000 1.000 1.000 

0802270000 8B Pepper, bell 0.001000 1.000 0.250 PDP da

 Full comment: PDP data

0802271000 8B Pepper, bell, dried 0.001000 1.000 0.250 PDP da

 Full comment: PDP data

0802271001 8B Pepper, bell, dried-babyfood 0.001000 1.000 0.250 PDP da

 Full comment: PDP data

0802270001 8B Pepper, bell-babyfood 0.001000 1.000 0.250 PDP da

 Full comment: PDP data
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 23 of 27

0802272000 8BC Pepper, nonbell 0.001000 1.000 0.250 PDP da

 Full comment: PDP data

0802273000 8BC Pepper, nonbell, dried 0.001000 1.000 0.250 PDP da

 Full comment: PDP data

0802272001 8BC Pepper, nonbell-babyfood 0.001000 1.000 0.250 PDP da

 Full comment: PDP data

0801374000 8A Tomatillo 0.010000 1.000 0.600 PDP da

 Full comment: PDP data

0801375000 8A Tomato 0.010000 1.000 0.600 PDP da

 Full comment: PDP data

0801380000 8A Tomato, Tree 0.010000 1.000 0.600 PDP da

 Full comment: PDP data

0801378000 8A Tomato, dried 0.010000 14.300 0.600 PDP da

 Full comment: PDP data

0801378001 8A Tomato, dried-babyfood 0.010000 14.300 0.600 PDP da

 Full comment: PDP data

0801379000 8A Tomato, juice 0.010000 1.500 0.600 PDP da

 Full comment: PDP data

0801376000 8A Tomato, paste 0.047500 1.000 0.600 PDP da

 Full comment: PDP data

0801376001 8A Tomato, paste-babyfood 0.047500 1.000 0.600 PDP da

 Full comment: PDP data

0801377000 8A Tomato, puree 0.010000 3.300 0.600 PDP da

 Full comment: PDP data

0801377001 8A Tomato, puree-babyfood 0.010000 3.300 0.600 PDP da

 Full comment: PDP data

0801375001 8A Tomato-babyfood 0.010000 1.000 0.600 PDP da

 Full comment: PDP data

0902021000 9B Balsam pear 0.050000 1.000 1.000 

0901075000 9A Cantaloupe 0.022000 1.000 0.250 PDP da

 Full comment: PDP data

0902088000 9B Chayote, fruit 0.050000 1.000 1.000 

0902102000 9B Chinese waxgourd 0.050000 1.000 1.000 

0902135000 9B Cucumber 0.050000 1.000 0.025 

0901187000 9A Honeydew melon 0.050000 1.000 0.200 

0902308000 9B Pumpkin 0.050000 1.000 0.050 

0902309000 9B Pumpkin, seed 0.050000 1.000 0.050 

0902356000 9B Squash, summer 0.050000 1.000 0.050 

0902356001 9B Squash, summer-babyfood 0.050000 1.000 0.050 

0902357000 9B Squash, winter 0.050000 1.000 0.050 

0902357001 9B Squash, winter-babyfood 0.050000 1.000 0.050 

0901399000 9A Watermelon 0.050000 1.000 0.100 

0901400000 9A Watermelon, juice 0.050000 1.000 0.100 

1001106000 10A Citron 0.050000 1.000 1.000 

1001107000 10A Citrus hybrids 0.050000 1.000 1.000 

1001108000 10A Citrus, oil 0.050000 1.000 1.000 

1003180000 10C Grapefruit 0.050000 1.000 0.010 

1003181000 10C Grapefruit, juice 0.050000 1.200 0.010 

1002197000 10B Kumquat 0.050000 1.000 1.000 

1002199000 10B Lemon 0.050000 1.000 0.010 

1002200000 10B Lemon, juice 0.050000 2.000 0.010 

1002200001 10B Lemon, juice-babyfood 0.050000 2.000 0.010 

1002201000 10B Lemon, peel 0.050000 1.000 0.010 

1002206000 10B Lime 0.050000 1.000 1.000 

1002207000 10B Lime, juice 0.050000 2.000 1.000 

1002207001 10B Lime, juice-babyfood 0.050000 2.000 1.000 

1001240000 10A Orange 0.015000 1.000 0.010 PDP da

 Full comment: PDP data

1001241000 10A Orange, juice 0.000500 1.000 0.010 PDP da

 Full comment: PDP data

1001241001 10A Orange, juice-babyfood 0.000500 1.000 0.010 PDP da

 Full comment: PDP data

1001242000 10A Orange, peel 0.015000 1.000 0.010 PDP da

 Full comment: PDP data

1003307000 10C Pummelo 0.050000 1.000 1.000 

1001369000 10A Tangerine 0.050000 1.000 1.000 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 24 of 27

1001370000 10A Tangerine, juice 0.050000 2.300 1.000 

1202012000 12B Apricot 0.050000 1.000 1.000 

1202013000 12B Apricot, dried 0.050000 6.000 1.000 

1202014000 12B Apricot, juice 0.050000 1.000 1.000 

1202014001 12B Apricot, juice-babyfood 0.050000 1.000 1.000 

1202012001 12B Apricot-babyfood 0.050000 1.000 1.000 

1201090000 12A Cherry 0.050000 1.000 1.000 

1201091000 12A Cherry, juice 0.050000 1.500 1.000 

1201091001 12A Cherry, juice-babyfood 0.050000 1.500 1.000 

1201090001 12A Cherry-babyfood 0.050000 1.000 1.000 

1202230000 12B Nectarine 0.050000 1.000 1.000 

1202260000 12B Peach 0.050000 1.000 0.010 

1202261000 12B Peach, dried 0.050000 7.000 0.010 

1202261001 12B Peach, dried-babyfood 0.050000 7.000 0.010 

1202262000 12B Peach, juice 0.050000 1.000 0.010 

1202262001 12B Peach, juice-babyfood 0.050000 1.000 0.010 

1202260001 12B Peach-babyfood 0.050000 1.000 0.010 

1203285000 12C Plum 0.050000 1.000 1.000 

1203287000 12C Plum, prune, dried 0.050000 5.000 1.000 

1203287001 12C Plum, prune, dried-babyfood 0.050000 5.000 1.000 

1203286000 12C Plum, prune, fresh 0.050000 1.000 1.000 

1203286001 12C Plum, prune, fresh-babyfood 0.050000 1.000 1.000 

1203288000 12C Plum, prune, juice 0.050000 1.400 1.000 

1203288001 12C Plum, prune, juice-babyfood 0.050000 1.400 1.000 

1203285001 12C Plum-babyfood 0.050000 1.000 1.000 

1304175000 13D Grape 0.050000 1.000 0.025 

1304176000 13D Grape, juice 0.050000 1.200 0.025 

1304176001 13D Grape, juice-babyfood 0.050000 1.200 0.025 

1304179000 13D Grape, wine and sherry 0.050000 1.000 0.025 

1400003000 14 Almond 0.050000 1.000 0.010 

1400004000 14 Almond, oil 0.050000 1.000 0.010 

1400004001 14 Almond, oil-babyfood 0.050000 1.000 0.010 

1400003001 14 Almond-babyfood 0.050000 1.000 0.010 

1400059000 14 Brazil nut 0.050000 1.000 1.000 

1400068000 14 Butternut 0.050000 1.000 1.000 

1400081000 14 Cashew 0.050000 1.000 1.000 

1400092000 14 Chestnut 0.050000 1.000 1.000 

1400155000 14 Hazelnut 0.050000 1.000 1.000 

1400156000 14 Hazelnut, oil 0.050000 1.000 1.000 

1400185000 14 Hickory nut 0.050000 1.000 1.000 

1400213000 14 Macadamia nut 0.050000 1.000 1.000 

1400269000 14 Pecan 0.050000 1.000 0.010 

1400278000 14 Pine nut 0.050000 1.000 1.000 

1400282000 14 Pistachio 0.050000 1.000 0.025 

1400391000 14 Walnut 0.050000 1.000 0.010 

1500027000 15 Barley, bran 0.050000 1.000 0.010 

1500026000 15 Barley, flour 0.050000 1.000 0.010 

1500026001 15 Barley, flour-babyfood 0.050000 1.000 0.010 

1500025000 15 Barley, pearled barley 0.050000 1.000 0.010 

1500025001 15 Barley, pearled barley-babyfood 0.050000 1.000 0.010 

1500122000 15 Corn, field, bran 0.050000 1.000 0.010 

1500120000 15 Corn, field, flour 0.050000 1.000 0.010 

1500120001 15 Corn, field, flour-babyfood 0.050000 1.000 0.010 

1500121000 15 Corn, field, meal 0.050000 1.000 0.010 

1500121001 15 Corn, field, meal-babyfood 0.050000 1.000 0.010 

1500125000 15 Corn, field, oil 0.050000 1.000 0.010 

1500125001 15 Corn, field, oil-babyfood 0.050000 1.000 0.010 

1500123000 15 Corn, field, starch 0.050000 1.000 0.010 

1500123001 15 Corn, field, starch-babyfood 0.050000 1.000 0.010 

1500124000 15 Corn, field, syrup 0.050000 1.500 0.010 

1500124001 15 Corn, field, syrup-babyfood 0.050000 1.500 0.010 

1500344000 15 Sorghum, grain 0.050000 1.000 0.010 

1500345000 15 Sorghum, syrup 0.050000 1.000 0.010 

1500401000 15 Wheat, grain 0.050000 1.000 0.010 

1500401001 15 Wheat, grain-babyfood 0.050000 1.000 0.010 

2003114001 20C Coconut, oil-babyfood 0.050000 1.000 1.000 
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 25 of 27

2003128000 20C Cottonseed, oil 0.050000 1.000 0.300 

2003128001 20C Cottonseed, oil-babyfood 0.050000 1.000 0.300 

2001163000 20A Flax seed, oil 0.050000 1.000 1.000 

2001319000 20A Rapeseed, oil 0.050000 1.000 0.025 

2001319001 20A Rapeseed, oil-babyfood 0.050000 1.000 0.025 

2002330000 20B Safflower, oil 0.050000 1.000 1.000 

2002330001 20B Safflower, oil-babyfood 0.050000 1.000 1.000 

2001337000 20A Sesame, oil 0.050000 1.000 1.000 

2001337001 20A Sesame, oil-babyfood 0.050000 1.000 1.000 

2001336000 20A Sesame, seed 0.050000 1.000 1.000 

2001336001 20A Sesame, seed-babyfood 0.050000 1.000 1.000 

2002365000 20B Sunflower, oil 0.050000 1.000 0.100 

2002365001 20B Sunflower, oil-babyfood 0.050000 1.000 0.100 

2002364000 20B Sunflower, seed 0.050000 1.000 0.100 

8601000000 86A Water, direct, all sources 0.001590 1.000 1.000 30 yr 

 Full comment: 30 yr avg

8602000000 86B Water, indirect, all sources 0.001590 1.000 1.000 30 yr 

 Full comment: 30 yr avg

Attachment 4: Cancer Food plus Water Results

US EPA Ver. 3.16, 03-08-d

DEEM-FCID Chronic analysis for TRIFLURALIN NHANES 2003-2008 2-day

Residue file name: C:\Documents and 

Settings\spiper\Desktop\Trifluralin\Dietary\Trifluralin_cancer_refined.r08

 Adjustment factor #2 used.

Analysis Date 01-31-2013/16:14:39 Residue file dated: 01-31-2013/16:13:57

Q* = 0.00296 

COMMENT 1: Cancer

===============================================================================

 Total exposure by population subgroup

-------------------------------------------------------------------------------

 Total Exposure

 -----------------------------------

 Population mg/kg Lifetime risk

 Subgroup body wt/day (Q*= .00296)

-------------------------------------- ------------- --------------

Total US Population 0.000070 2.07E-07

Hispanic 0.000070 2.06E-07

Non-Hisp-White 0.000070 2.07E-07

Non-Hisp-Black 0.000064 1.90E-07

Non-Hisp-Other 0.000084 2.47E-07

Nursing Infants 0.000108 3.20E-07

Non-Nursing Infants 0.000231 6.83E-07

Female 13+ PREG 0.000067 1.97E-07

Children 1-6 0.000126 3.73E-07

Children 7-12 0.000070 2.08E-07

Male 13-19 0.000048 1.42E-07

Female 13-19/NP 0.000051 1.50E-07

Male 20+ 0.000060 1.78E-07

Female 20+/NP 0.000067 1.98E-07

Seniors 55+ 0.000066 1.96E-07

All Infants 0.000193 5.71E-07

Female 13-50 0.000062 1.84E-07

Children 1-2 0.000147 4.34E-07

Children 3-5 0.000119 3.52E-07

Children 6-12 0.000075 2.22E-07

Youth 13-19 0.000049 1.46E-07

Adults 20-49 0.000062 1.83E-07

Adults 50-99 0.000066 1.96E-07

Female 13-49 0.000062 1.83E-07
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 26 of 27

-------------------------------------------------------------------------------

Attachment 5: Trifluralin Screening Level Usage Analysis (SLUA)

December 7, 2012

Screening Level Estimates of Agricultural Uses of Trifluralin (036101)

Sorted Alphabetically

Reporting Years: 2004-2011

Percent Crop Treated

Crop Lbs. A.I. Avg. Max.

1 Alfalfa 400,000 <2.5 <2.5

2 Almonds 7,000 <1 <2.5

3 Apples <500 <1 <2.5

4 Apricots * <500 NC NC

5 Asparagus 10,000 20 30

6 Barley 4,000 <1 <2.5

7 Beans, Green 40,000 25 35

8 Broccoli 6,000 10 25

9 Brussels Sprouts * <500 NC NC

10 Cabbage 20,000 40 60

11 Canola 9,000 <2.5 <2.5

12 Cantaloupes 10,000 25 45

13 Carrots 30,000 40 65

14 Cauliflower 2,000 10 20

15 Celery <500 <2.5 5

16 Chicory * <500 NC NC

17 Corn 80,000 <1 <2.5

18 Cotton 3,200,000 30 35

19 Cucumbers 3,000 <2.5 10

20 Dry Beans/Peas 200,000 10 20

21 Fallow 40,000 <1 <2.5

22 Garlic 1,000 5 10

23 Grapefruit 1,000 <1 <2.5

24 Grapes 20,000 <2.5 <2.5

25 Honeydews 3,000 20 35

26 Lemons <500 <1 <2.5

27 Lettuce 4,000 <2.5 <2.5

28 Nectarines * <500 NC NC

29 Onions 1,000 <2.5 5
Trifluralin Dietary Exposure and Risk Assessment DP Number: 410618

Page 27 of 27

30 Oranges 10,000 <1 <2.5

31 Peaches <500 <1 <2.5

32 Peanuts 30,000 5 10

33 Peas, Green 9,000 10 20

34 Pecans 2,000 <1 <2.5

35 Peppers 10,000 25 40

36 Pistachios 1,000 <2.5 <2.5

37 Plums/Prunes * <500 NC NC

38 Potatoes 10,000 <2.5 5

39 Pumpkins 3,000 5 10

40 Sorghum 30,000 <1 <2.5

41 Soybeans 1,700,000 5 10

42 Spinach <500 <1 <2.5

43 Squash 1,000 5 10

44 Strawberries <500 <1 <2.5

45 Sugar Beets 10,000 <2.5 5

46 Sugarcane 100,000 5 10

47 Sunflowers 200,000 10 20

48 Sweet Corn 1,000 <1 <2.5

49 Tobacco+ 1,000 <1 <2.5

50 Tomatoes 100,000 60 70

51 Walnuts 2,000 <1 <2.5

52 Watermelons 20,000 10 20

53 Wheat 60,000 <1 <2.5

All numbers are rounded.

<500: indicates less than 500 pounds of active ingredient.

 <2.5: indicates less than 2.5 percent of crop is treated.

 <1: indicates less than 1 percent of crop is treated.

* Based on CA DPR data only (80% or more of U.S. acres grown are in California)

NC: not calculated, only pounds a.i. available. 

+ Crops not known to be listed on active end use product registrations or as Section 18 emergency exemptions when this 

report was run

SLUA data sources include: 

USDA-NASS (United States Department of Agriculture's National Agricultural Statistics Service) 

Private Pesticide Market Research

California DPR (Department of Pesticide Regulation)

These results reflect amalgamated data developed by the Agency and are releasable to the public.