Base Note Hedge Transaction Confirmation, dated as of May 10, 2012



 Exhibit 10.1 

 
  

									
		  		  		  	Deutsche Bank




	  	  	 	  	 	  	  
 Deutsche Bank AG, London Branch

Winchester house
 1 Great Winchester
St,
 London EC2N 2DB

Telephone: 44 20 7545 8000
  

c/o Deutsche Bank Securities Inc.
 60 Wall Street
 New York, NY 10005
 Telephone: 212-250-2500
	  	 
					
	DATE:	  	May 10, 2012	  		  		  	
				
	TO:	  	Medicis Pharmaceutical Corporation	  		  	
		  	7720 North Dobson Road	  		  		  	
		  	Scottsdale, Arizona 85256	  		  		  	
	ATTENTION:	  	Richard D. Peterson	  		  		  	
	FACSIMILE:	  	(480) 291-8847	  		  		  	
				
	FROM:	  	Deutsche Bank AG, London Branch	  		  	
					
	SUBJECT:	  	Base Note Hedge Transaction	  		  		  	
					
	REFERENCE NUMBER(S):	  	486862	  		  		  	

 The purpose of this agreement (this “Confirmation”) is to confirm the terms and conditions of the
transaction entered into between Deutsche Bank AG, London Branch (“Dealer”) and Medicis Pharmaceutical Corporation (“Counterparty”) on the Trade Date specified below (the “Transaction”). This
Confirmation constitutes a “Confirmation” as referred to in the ISDA Master Agreement specified below. This Confirmation constitutes the entire agreement and understanding of the parties with respect to the subject matter and terms of the
Transaction and supersedes all prior or contemporaneous written and oral communications with respect thereto. 
 DEUTSCHE BANK AG IS NOT
REGISTERED AS A BROKER OR DEALER UNDER THE U.S. SECURITIES EXCHANGE ACT OF 1934, AS AMENDED. DEUTSCHE BANK SECURITIES INC. (“AGENT”) HAS ACTED SOLELY AS AGENT IN CONNECTION WITH THE TRANSACTION AND HAS NO OBLIGATION, BY WAY OF ISSUANCE,
ENDORSEMENT, GUARANTEE OR OTHERWISE WITH RESPECT TO THE PERFORMANCE OF EITHER PARTY UNDER THE TRANSACTION. AS SUCH, ALL DELIVERY OF FUNDS, ASSETS, NOTICES, DEMANDS AND COMMUNICATIONS OF ANY KIND RELATING TO THE TRANSACTION BETWEEN DEUTSCHE BANK AG
AND COUNTERPARTY SHALL BE TRANSMITTED EXCLUSIVELY THROUGH AGENT. DEUTSCHE BANK AG, LONDON BRANCH IS NOT A MEMBER OF THE SECURITIES INVESTOR PROTECTION CORPORATION (SIPC). 

 

			
	Chairman of the Supervisory Board: Clemens Börsig Management Board: Josef Ackermann (Chairman), Hugo Bänziger, Jürgen Fitschen, Anshuman Jain, Stefan Krause,
Hermann-Josef Lamberti, Rainer Neske	 	Deutsche Bank AG is authorised under German Banking Law (competent authority: BaFin – Federal Financial Supervising Authority) and regulated by the Financial Services Authority
for the conduct of UK business; a member of the London Stock Exchange. Deutsche Bank AG is a joint stock corporation with limited liability incorporated in the Federal Republic of Germany HRB No. 30 000 District Court of Frankfurt am Main; Branch
Registration in England and Wales BR000005; Registered address: Winchester House, 1 Great Winchester Street, London EC2N 2DB. Deutsche Bank Group online: http://www.deutsche-bank.com








 The definitions contained in the 2002 ISDA Equity Derivatives Definitions (the “Equity
Definitions”), as published by the International Swaps and Derivatives Association, Inc., are incorporated into this Confirmation. In the event of any inconsistency between the Equity Definitions and the terms of this Confirmation, the
terms of this Confirmation shall govern, and in the event of any inconsistency between either the Equity Definitions or this Confirmation and the Agreement (as defined below), the Equity Definitions or this Confirmation, as the case may be, shall
govern. For the avoidance of doubt, except to the extent of an express conflict, the application of any provision of this Confirmation, the Agreement or the Equity Definitions shall not be construed to exclude or limit the application of any other
provision of this Confirmation, the Agreement or the Equity Definitions. For the purposes of the Equity Definitions, each reference herein to a Note Hedging Unit shall be deemed to be a reference to a Call or an Option, as context requires.

 This Confirmation evidences a complete and binding agreement between Dealer and Counterparty as to the terms of the Transaction to which this
Confirmation relates. This Confirmation shall supplement, form a part of, and be subject to an agreement (the “Agreement”) in the form of the ISDA 2002 Master Agreement as if Dealer and Counterparty had executed an agreement in such
form (without any Schedule but with the election that the “Cross Default” provisions of Section 5(a)(vi) of the Agreement shall apply to both parties, provided that (i) the phrase “or becoming capable at such time of being
declared” shall be deleted from clause (1) of such Section 5(a)(vi); (ii) the following language shall be added to the end thereof: “Notwithstanding the foregoing, a default under subsection (2) hereof shall not
constitute an Event of Default if (i) the default was caused solely by error or omission of an administrative or operational nature; (ii) funds were available to enable the party to make the payment when due; and (iii) the payment is
made within two Local Business Days of such party’s receipt of written notice of its failure to pay.”; (iii) “Specified Indebtedness” will have the meaning specified in Section 14 of the Agreement, except that such term
shall not include obligations in respect of deposits received in the ordinary course of a party’s banking business; and (iv) “Threshold Amount” means, in relation to Dealer, three percent (3%) of shareholders’ equity of
Deutsche Bank AG as of the Trade Date, and in relation to Counterparty, USD 25 million, and with such other elections set forth in this Confirmation). The Transaction shall be the only transaction under the Agreement. 

The Transaction shall be considered a Share Option Transaction for purposes of the Equity Definitions, and shall have the following terms: 

 

			
	General:	  	 
		
	Trade Date:	  	May 10, 2012.
		
	Effective Date:	  	The closing date for the initial issuance of the Convertible Notes.
		
	Transaction Style:	  	Modified American, as described below under “Procedure for Exercise”.
		
	Transaction Type:	  	Note Hedging Units.
		
	Seller:	  	Dealer.
		
	Buyer:	  	Counterparty.
		
	Shares:	  	The Class A common stock, par value USD 0.014 per share, of Counterparty.


 

			
		
	Convertible Notes:	  	1.375% Convertible Senior Notes of Counterparty due 2017, offered pursuant to a Prospectus to be dated as of May 10, 2012, as supplemented by a Prospectus Supplement dated as
of May 10, 2012, and to be issued pursuant to an indenture (the “Base Indenture”) to be dated on or about May 16, 2012 (the “Execution Date”), as supplemented and amended by a supplemental indenture (the
“Supplemental Indenture”), dated as of the Execution Date, each by


  
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		  	and between Counterparty and Deutsche Bank Trust Company Americas, as trustee (the Base Indenture as so supplemented and amended, the “Indenture”). References herein to
the Indenture, the Base Indenture or the Supplemental Indenture are based on the drafts of the Base Indenture and Supplemental Indenture most recently reviewed by the parties at the time of execution of this Confirmation. If any relevant sections of
such documents are changed, added or renumbered upon execution thereof, the parties will amend this Confirmation in good faith to preserve the economic intent of the parties. Subject to the foregoing, any reference herein to the Indenture, the Base
Indenture or the Supplemental Indenture shall be to such instrument as of the Execution Date, without giving effect to any amendment, supplement or modification thereto other than, subject to the provision set forth under “Settlement
Amount” below relating to Counterparty Determinations, a Merger Supplemental Indenture (as defined below). If any amendment or supplement is made to the Indenture following the Execution Date (other than (A) pursuant to a Merger
Supplemental Indenture or (B) any amendment pursuant to Section 6.01(j) of the Supplemental Indenture that, as determined by the Calculation Agent, conforms the Supplemental Indenture to the description of the Convertible Notes in the
preliminary prospectus supplement as supplemented by the issuer free writing prospectus, in each case, related to the offering of the Convertible Notes) (x) the Calculation Agent shall determine the relevant Settlement Amount and Settlement
Date for any Note Hedging Unit exercised thereafter in accordance with this Confirmation by referring to the relevant provisions of the Indenture without giving effect to such amendment or supplement, and (y) such supplement or amendment shall
be disregarded for all other purposes hereunder. Counterparty shall deliver to Dealer a copy of any amendment to the Indenture described in clause (B) of the parenthetical in the immediately preceding sentence prior to the effectiveness of such
amendment. Terms in quotation marks that are not otherwise defined in this Confirmation shall have the meanings set forth in the Indenture, unless the context requires otherwise.
		
	Number of Note Hedging Units:	  	270,000, as reduced by any Note Hedging Units exercised hereunder.
		
	Note Hedging Unit Entitlement:	  	USD1,000 divided by the Strike Price.
		
	Strike Price:	  	USD 47.075
		
	Applicable Percentage:	  	60%.
		
	Premium:	  	As provided in Annex A to this Confirmation.
		
	Premium Payment Date:	  	The Effective Date.
		
	Exchange:	  	The New York Stock Exchange.
		
	Related Exchanges:	  	All Exchanges.


  
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	Calculation Agent:	  	Dealer, whose judgments, determinations and calculations shall be made in good faith and in a commercially reasonable manner. Following any determination or calculation by the
Calculation Agent hereunder, upon a written request by Counterparty, the Calculation Agent will provide to Counterparty by e-mail to the e-mail address provided by Counterparty in such written request a report (in a commonly used file format for the
storage and manipulation of financial data) displaying in reasonable detail the basis for such calculation, it being understood that the Calculation Agent shall not be obligated to disclose any proprietary models used by it for such
calculation.
		
	 Procedure for Exercise:
	  	
		
	 Potential Exercise Dates:
	  	Each Conversion Date.
		
	 Conversion Date:
	  	Each “Conversion Date”.
		
	 Required Exercise on Conversion Dates:
	  	On each Conversion Date, a number of Note Hedging Units equal to the product of (A) the Applicable Percentage and (B) the number of Convertible Notes in denominations of
USD1,000 principal amount submitted for conversion in respect of such Conversion Date in accordance with the terms of the Indenture shall be exercised automatically, subject to “Notice of Exercise” below; provided that in no event
will the number of Note Hedging Units exercised or deemed exercised hereunder exceed the Number of Note Hedging Units. For the avoidance of doubt, if the immediately preceding sentence would result in the exercise of a fraction of a Note Hedging
Unit on any day, the number of Shares and/or amount of cash deliverable in respect of such portion of a Note Hedging Unit shall be equal to the product of such fraction and the Settlement Amount applicable to a full Note Hedging Unit exercised on
such day.
		
	 Expiration Date:
	  	June 1, 2017
		
	 Multiple Exercise:
	  	Applicable, as provided under “Required Exercise on Conversion Dates”.
		
	 Automatic Exercise:
	  	As provided under “Required Exercise on Conversion Dates”.
		
	Notice of Exercise:	  	 Notwithstanding anything to the contrary herein or in the Equity Definitions, in order to exercise any Note Hedging Units, Counterparty
must (x) notify Dealer in writing and (y) confirm receipt by telephone to (212) 250-0668, in each case, prior to 5:00 PM, New York City time, on the “Scheduled Trading Day” prior to the first day of the “Conversion Period”
relating to the Convertible Notes converted on the Conversion Date relating to the relevant Exercise Date (the “Notice Deadline”) of:
  

(i) the aggregate principal amount of Convertible Notes as to which the related “Conversion Date” has occurred (including,
if applicable, whether all or any portion of such Convertible Notes are Convertible Notes as to which “Additional Shares” would be added to the “Conversion Rate” pursuant to Section 8.03 of the Supplemental Indenture (the
“Make-Whole Convertible Notes”)),



  
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		  	 (ii) the scheduled commencement date of the “Conversion Period” and the scheduled settlement date under
the Indenture for the Convertible Notes converted on the Conversion Date corresponding to such Exercise Date, and
  

(iii) the applicable “Cash Percentage”; provided that, if the “Cash Percentage” specified is a percentage other
than 0%, such notice shall contain an acknowledgment by Counterparty of its responsibilities under applicable securities laws, and in particular, Section 9 and 10(b) of the U.S. Securities Act of 1934, as amended (the “Exchange
Act”) and the rules and regulations thereunder, in respect of any election of a “Cash Percentage” settlement method with respect to the relevant Convertible Notes; provided, further that if Counterparty fails to timely provide the
notice described in this clause (iii) or such notice does not contain the foregoing acknowledgment to the extent required by this clause (iii), notwithstanding anything to the contrary under “Settlement Amount” below, the Settlement Amount
for each relevant Note Hedging Unit shall be the Settlement Amount (as determined by the Calculation Agent) that would have been deliverable hereunder by Dealer with respect to such Note Hedging Unit if Counterparty had elected a “Cash
Percentage” of 0%.
  
 Notwithstanding the foregoing, in respect of
Convertible Notes with a Conversion Date during the period beginning on, and including, March 1, 2017 and ending at the close of business on the second “Scheduled Trading Day” immediately preceding the “Maturity
Date”:
  
 (x) the Notice Deadline in respect of
the information set forth in clause (i) above shall be 5:00 PM, New York City time, on the “Scheduled Trading Day” immediately preceding the “Maturity Date,”

 
 (y) the Notice of Exercise need not include the information
set forth in clause (ii) above, and
  
 (z) the Notice
Deadline in respect of the information set forth in clause (iii) above shall be 5:00 PM, New York City time, on the second “Scheduled Trading Day” immediately following March 1, 2017.

 
 For the avoidance of doubt, if Counterparty fails to give a Notice of Exercise when
due in respect of any exercise of Note Hedging Units hereunder as set forth above, Dealer’s obligation to make any payment or delivery in respect of such exercise shall be permanently extinguished, and late notice shall not cure such failure;
provided that a Notice of Exercise (and the related exercise of Note Hedging Units) shall be effective with respect to Note Hedging Units relating to Convertible Notes converted prior to March 1, 2017, if given after the Notice Deadline but
prior to 5:00 PM New York City time on the fifth Scheduled Trading Day following the Notice Deadline, in which event the Calculation Agent shall have the right to adjust the applicable Settlement Amount as appropriate to reflect the additional costs
(including, but not limited to, hedging mismatches and market losses) and reasonable expenses incurred by Dealer in connection with its hedging activities (including the unwinding of any hedge position) as a result of Dealer not having received such
notice on or prior to the Notice Deadline.



  
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	Settlement Terms:	  	
		
	 Settlement:
	  	 In lieu of the obligations set forth in Sections 8.1 and 9.1 of the Equity Definitions, and subject to “Notice of Exercise”
above, in respect of any validly exercised Note Hedging Unit, Dealer shall deliver to Counterparty, on the related Settlement Date, the Settlement Amount.
  

For the avoidance of doubt, to the extent Dealer is obligated to deliver Shares hereunder, the provisions of Sections 9.8, 9.9, 9.11 and 9.12 of the
Equity Definitions shall be applicable to any such delivery of Shares, except that all references in such provisions to “Physical Settlement” and “Physically-settled” shall be read as references to “Share Settlement”
and “Share Settled”; and provided that the Representation and Agreement contained in Section 9.11 of the Equity Definitions shall be modified by excluding any representations therein relating to restrictions, obligations,
limitations or requirements under applicable securities laws arising from Counterparty’s status as issuer of the Shares or arising from such Shares being “restricted securities” (as defined in Rule 144 under the Securities Act of
1933, as amended (the “Securities Act”)). “Share Settlement” means settlement of a Note Hedging Unit pursuant to “Settlement Amount” below, and “Share Settled” has a meaning correlative
thereto.

		
	Settlement Amount:	  	 The aggregate of (i) the number of Shares that Counterparty is obligated to deliver and (ii) the amount of cash that Counterparty is
obligated to pay less USD 1,000, in each case, to the holder of USD 1,000 principal amount of Convertible Notes converted on such Conversion Date pursuant to Section 8.02 of the Supplemental Indenture.

 
 The number of Shares included in the Settlement Amount shall not take into
consideration any rounding pursuant to Section 8.02(j) of the Supplemental Indenture. Instead Dealer will deliver cash in lieu of any fractional Shares based on (i) the “Daily VWAP” on the last “Trading Day” of the
applicable “Conversion Period” and (ii) the aggregate number of Note Hedging Units exercised on any Exercise Date.
  

In addition, and notwithstanding anything to the contrary herein:
  

(i) the Settlement Amount shall be determined by the Calculation Agent excluding any increase to the “Conversion Rate”
pursuant to Section 8.03 of the Supplemental Indenture (a “Fundamental Change Adjustment”) or any voluntary adjustment to the “Conversion Rate” pursuant to Section 8.04(g) of the Supplemental Indenture (a
“Discretionary Adjustment”); and



  
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		  	 (ii) if Counterparty or its board of directors is permitted or required to exercise discretion under the terms of
the Indenture with respect to any determination, calculation or adjustment (including, without limitation, any adjustment under Section 8.04(i) or 8.05 of the Supplemental Indenture, any adjustment to the terms of the Convertible Notes following a
Merger Event pursuant to Section 8.07 of the Supplemental Indenture, any adjustment to the “Dividend Threshold Amount” relating to a change in the regular dividend period for purposes of Section 8.04(d) of the Supplemental Indenture or any
determination of the fair market value of distributed property, the volume weighted average price of Shares or the value of a “unit of Reference Property”) (any such determination, calculation or adjustment, a “Counterparty
Determination”), Counterparty shall consult with Dealer with respect thereto and, if the Calculation Agent disagrees in good faith with such determination, calculation or adjustment, notwithstanding anything herein to the contrary, the
Calculation Agent shall make the relevant determination, calculation or adjustment for purposes of the Transaction (and, for the avoidance of doubt, such determination, calculation or adjustment shall be made (A) in accordance with the
methodology set forth in the Indenture, except as set forth herein, and (B) using, where relevant, variables determined by the Calculation Agent).
  

Notwithstanding the foregoing, in no event shall the sum of (x) the product of the number of Shares delivered in respect of a Note Hedging Unit and the
Applicable Limit Price on the Settlement Date for such Note Hedging Unit and (y) the amount of cash paid in respect of any Note Hedging Unit (including any cash in lieu of any fractional Share), exceed the Applicable Limit for such Note Hedging
Unit.
  
 Section 6.3(a) of the Equity Definitions is hereby amended by
deleting the remainder of clause (ii) thereof following the words “at any time.”

		
	 Applicable Limit:
	  	For any exercised Note Hedging Unit, an amount in USD equal to the product of the Applicable Percentage and the excess of (i) the sum of (A) the amount of cash, if any, paid to the
holder of USD 1,000 principal amount of Convertible Notes converted on the related Conversion Date and (B) the product of (x) the number of Shares, if any, delivered to the holder of USD 1,000 principal amount of Convertible Notes converted on the
related Conversion Date and (y) the Applicable Limit Price on the applicable Settlement Date over (ii) USD 1,000.
		
	 Applicable Limit Price:
	  	On any day, the opening price as displayed under the heading “Op” on Bloomberg page MRX <equity> (or any successor thereto).


  
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	Notice of Delivery Obligation:	  	 No later than the “Scheduled Trading Day” immediately following the last day of the relevant “Conversion Period,”
Counterparty shall give Dealer notice of the final number of Shares and/or the amount of cash that Counterparty is required to deliver to holders of the relevant Convertible Notes (the “Convertible Obligation”); provided
that:
  
 (i) Counterparty may provide a single such
notice of the aggregate Convertible Obligation for all Convertible Notes converted on or after March 1, 2017,
  

(ii) the requirement of Counterparty to deliver such notice shall not limit Counterparty’s obligations with respect to
Notice of Exercise, as set forth above, in any way; and
  

(iii) in the case of any late delivery of a Notice of Delivery Obligation, notwithstanding anything to the contrary herein, the
Settlement Date for any related Note Hedging Unit shall be the second Scheduled Trading Day following the date such notice is delivered; provided, further, that if Counterparty fails to deliver such notice prior to 5:00 PM New York City time on the
fifth “Scheduled Trading Day” following the last day of the relevant “Conversion Period,” Dealer’s obligation to make any payment or delivery in respect of the related exercise of Note Hedging Units shall be permanently
extinguished and any delivery of such notice thereafter shall not cure such failure.

		
	 Settlement Date:
	  	In respect of an Exercise Date, the settlement date for the Shares or cash to be delivered under the Convertible Notes converted on the corresponding Conversion Date under the terms
of the Indenture.
		
	 Settlement Currency:
	  	USD.
		
	 Restricted Certificated Shares:
	  	Notwithstanding anything to the contrary in the Equity Definitions, Dealer may, in whole or in part, deliver Shares in certificated form representing the Share portion of the
Settlement Amount to Counterparty in lieu of delivery through the Clearance System.
		
	Share Adjustments:	  	
		
	Potential Adjustment Events:	  	 Notwithstanding Section 11.2(e) of the Equity Definitions, a “Potential Adjustment Event” means any occurrence of any event or
condition, as set forth in Section 8.04(i), 8.04(a)–(e) or 8.05 of the Supplemental Indenture, that would result in an adjustment under the Indenture to the “Conversion Rate” or any other term of the Convertible Notes; provided that
in no event shall there be any adjustment hereunder as a result of a Fundamental Change Adjustment or a Discretionary Adjustment.
  

Notwithstanding anything to the contrary herein, (i) Dealer shall not have any delivery obligation hereunder in respect of any “Distributed
Property” delivered by Counterparty to which the fifth sentence of Section 8.04(c) of the Supplemental Indenture would apply and no adjustment shall be made to the terms of the Transaction on account of the delivery of such “Distributed
Property” to holders of the Shares and (ii) if Counterparty pays a cash dividend to which the last paragraph of Section 8.04(d) of the Supplemental Indenture would apply, Dealer will pay to Counterparty an amount of cash equal to the amount of
such cash dividend that Dealer or its affiliate receives on its Hedge Positions in respect of the Transaction promptly following Dealer’s receipt thereof.



  
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	 Method of Adjustment:
	  	Calculation Agent Adjustment, which means that, notwithstanding Section 11.2(c) of the Equity Definitions, upon any Potential Adjustment Event (excluding, for the avoidance of
doubt, any Fundamental Change Adjustment or Discretionary Adjustment), the Calculation Agent shall make a corresponding adjustment to any one or more of the Strike Price, Number of Note Hedging Units, the Note Hedging Unit Entitlement, the
composition of the Shares and any other variable relevant to the exercise, settlement, payment or other terms of the Transaction (subject to the provisions set forth under “Settlement Amount” above in respect of any Counterparty
Determination).
		
	 Dividends:
	  	If (i) an ex-dividend date for a cash dividend or distribution on the Shares (a “Triggering Dividend”) that is less than the Regular Dividend occurs on or
after the Trade Date and on or prior to the Expiration Date, or (ii) no ex-dividend date for a cash dividend or distribution on the Shares occurs in any regular dividend period of Counterparty (as determined by the Calculation Agent) that
falls, in whole or in part, after the Trade Date and on or prior to the Expiration Date, then, in each case, the Calculation Agent will make such adjustments to any one or more of the variables relevant to the exercise, settlement or payment or
other terms of the Transaction as it determines appropriate to account for the economic effect on the Transaction of such shortfall or lack of a dividend, as the case may be.
		
	 Regular Dividend:
	  	For the first Triggering Dividend for which the ex-dividend date occurs within any regular dividend period of Counterparty (as determined by the Calculation Agent), USD 0.10 per
Share (subject to adjustment (x) by the Calculation Agent to account for any change in the regular dividend period length and (y) as contemplated by Section 11.2(c) of the Equity Definitions), and, for any subsequent Triggering Dividend
for which the ex-dividend date occurs within the same regular dividend period, zero.
		
	Extraordinary Events:	  	
		
	 Merger Events:
	  	Notwithstanding Section 12.1(b) of the Equity Definitions, a “Merger Event” means the occurrence of any event or condition set forth in the definition of “Merger
Event” in Section 8.07(a) of the Supplemental Indenture.
		
	Notice of Merger Consideration:	  	In respect of any Merger Event, Counterparty shall notify the Calculation Agent of (i) if applicable, the weighted average of the kind and amounts of consideration to be received by
the holders of Shares in any Merger Event who affirmatively make such an election and (ii) the details of the adjustments made under the Indenture in respect of such Merger Event, in each case, reasonably promptly upon determination thereof (and in
any event prior to the effective date of the Merger Event), and Counterparty shall deliver a copy of the supplemental indenture effecting such adjustments (a “Merger Supplemental Indenture”) as promptly as practicable following
execution thereof.


  
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	 Consequences of Merger Events:
	  	Notwithstanding Section 12.2 of the Equity Definitions, upon the occurrence of a Merger Event, the Calculation Agent shall make the corresponding adjustment in respect of any
adjustment under the Indenture to any one or more of the nature of the Shares, the Strike Price, the Number of Note Hedging Units, the Note Hedging Unit Entitlement, the Settlement Date and any other variable relevant to the exercise, settlement or
payment or other terms of the Transaction to the extent an analogous adjustment is permitted or required to be made pursuant to the Indenture in connection with such Merger Event (subject to the provisions set forth under “Settlement
Amount” above in respect of any Counterparty Determination); provided that such adjustment shall be made without regard to any Fundamental Change Adjustment or any Discretionary Adjustment; and provided further that the
Calculation Agent may limit or alter any such adjustment referenced in this paragraph to preserve the intended economic benefits of the Transaction; and provided further that if, with respect to a Merger Event, (i) the consideration for
the Shares includes (or, at the option of a holder of Shares, may include) shares (or depositary receipts with respect to shares) of an entity or person that is not a corporation organized under the laws of the United States, any State thereof or
the District of Columbia or (ii) Counterparty following such Merger Event will not be a corporation organized under the laws of the United States, any State thereof or the District of Columbia or will not be either (x) the Issuer following such
Merger Event or (y) a wholly-owned subsidiary of the Issuer following such Merger Event whose obligations under the Transaction are fully and unconditionally guaranteed by such Issuer, Cancellation and Payment (Calculation Agent Determination) may
apply at Dealer’s sole election.
		
	 Nationalization, Insolvency and Delisting:
	  	Cancellation and Payment (Calculation Agent Determination); provided that in addition to the provisions of Section 12.6(a)(iii) of the Equity Definitions, it shall also
constitute a Delisting if the Exchange is located in the United States and the Shares are not immediately re-listed, re-traded or re-quoted on any of the New York Stock Exchange, The NASDAQ Global Select Market or The NASDAQ Global Market (or their
respective successors); if the Shares are immediately re-listed, re-traded or re-quoted on any such exchange or quotation system, such exchange or quotation system shall thereafter be deemed to be the
Exchange.


  
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	Additional Disruption Events:	  	
		
	Change in Law:	  	Applicable; provided that Section 12.9(a)(ii) of the Equity Definitions is hereby amended (i) by inserting the parenthetical “(including, for the avoidance of doubt and
without limitation, adoption or promulgation of new regulations authorized or mandated by existing statute)” at the end of clause (A) thereof, (ii) by the replacement of the word “Shares” with “Hedge Positions” in clause (X)
thereof; (iii) by adding the phrase “or announcement” immediately after the phrase “due to the promulgation” in the third line thereof and adding the phrase “formal or informal” before the word
“interpretation” in the same line; (iv) immediately following the word “Transaction” in clause (X) thereof, adding the phrase “in the manner contemplated by the Hedging Party on the Trade Date” and (v) adding the
following proviso to the end of clause (Y) thereof: “provided that such party has used commercially reasonable efforts to avoid such increased cost on terms acceptable to the Hedging Party”.
		
	 Failure to Deliver:
	  	Not Applicable
		
	 Insolvency Filing:
	  	Applicable
		
	 Hedging Disruption:
	  	 Applicable; provided that:
  

(i)     Section 12.9(a)(v) of the Equity Definitions is hereby amended by (a) inserting
the following words at the end of clause (A) thereof: “in the manner contemplated by the Hedging Party on the Trade Date” and (b) inserting the following two phrases at the end of such Section:

 
 “For the avoidance of doubt, the term “equity price
risk” shall be deemed to include, but shall not be limited to, stock price and volatility risk. And, for the further avoidance of doubt, any such transactions or assets referred to in phrases (A) or (B) above must be available on commercially
reasonable pricing terms.”; and
  
 (ii)    Section 12.9(b)(iii) of the Equity Definitions is hereby amended by inserting in the third line thereof, after the words “to terminate the Transaction”, the words
“or a portion of the Transaction affected by such Hedging Disruption”.

		
	 Increased Cost of Hedging:
	  	Not Applicable
		
	 Hedging Party:
	  	Dealer for all applicable Additional Disruption Events
		
	 Determining Party:
	  	Dealer for all applicable Extraordinary Events
		
	 Acknowledgements:
	  	
		
	 Non-Reliance:
	  	Applicable
		
	 Agreements and Acknowledgements
	  	
	 Regarding Hedging Activities:
	  	Applicable
		
	 Additional Acknowledgements:
	  	Applicable


  
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 Mutual Representations: Each of Dealer and Counterparty represents and warrants to, and agrees with,
the other party that: 
  

	 	(i)	Tax Disclosure. Notwithstanding anything to the contrary herein, in the Equity Definitions or in the Agreement, and notwithstanding any express or implied claims
of exclusivity or proprietary rights, the parties (and each of their employees, representatives or other agents) are authorized to disclose to any and all persons, beginning immediately upon commencement of their discussions and without limitation
of any kind, the tax treatment and tax structure of the Transaction, and all materials of any kind (including opinions or other tax analyses) that are provided by either party to the other relating to such tax treatment and tax structure.


  

	 	(ii)	Commodity Exchange Act. It is an “eligible contract participant” within the meaning of the U.S. Commodity Exchange Act, as amended (the
“CEA”). The Transaction has been subject to individual negotiation by the parties. The Transaction has not been executed or traded on a “trading facility” as defined in the CEA. 


 

	 	(iii)	Securities Act. It is a “qualified institutional buyer” as defined in Rule 144A under the Securities Act. 


Counterparty Representations: Counterparty hereby represents, warrants, acknowledges and covenants that: 

 

	 	(i)	Counterparty is not as of the Trade Date, and shall not be after giving effect to the transactions contemplated hereby, “insolvent” (as such term is defined
in Section 101(32) of the U.S. Bankruptcy Code (Title 11 of the United States Code) (the “Bankruptcy Code”)) and Counterparty would be able to purchase 13,276,700 Shares in compliance with the laws of the jurisdiction of
Counterparty’s incorporation or organization. 

  

	 	(ii)	Counterparty shall immediately provide written notice to Dealer upon obtaining knowledge of the occurrence of any event that would constitute an Event of Default, a
Potential Event of Default or a Potential Adjustment Event; provided, however, that should Counterparty be in possession of material non-public information regarding Counterparty, Counterparty shall not communicate such information to Dealer
in connection with this Transaction until such information no longer constitutes material non-public information. In addition, Counterparty shall reasonably promptly provide written notice to Dealer of any adjustment that is made under the Indenture
on account of any Potential Adjustment Event. 

  

	 	(iii)	Counterparty’s financial condition is such that it has no need for liquidity with respect to its investment in the Transaction and no need to dispose of any
portion thereof to satisfy any existing or contemplated undertaking or indebtedness. 

  

	 	(iv)	Counterparty’s investments in and liabilities in respect of the Transaction, which it understands are not readily marketable, are not disproportionate to its net
worth, and Counterparty is able to bear any loss in connection with the Transaction, including the loss of its entire investment in the Transaction. 

  

	 	(v)	The representations and warranties of Counterparty set forth in Section 3 of the Agreement and Section 1 of the Underwriting Agreement dated as of the Trade Date
between Counterparty and Deutsche Bank Securities Inc. and J.P. Morgan Securities LLC as representatives of the underwriters party thereto (the “Underwriting Agreement”) are true and correct and are hereby deemed to be repeated to
Dealer as if set forth herein. 


  
 12 










	 	(vi)	Counterparty understands, agrees and acknowledges that Dealer has no obligation or intention to register the Transaction under the Securities Act, any state securities
law or other applicable federal securities law. 

  

	 	(vii)	Counterparty is not, and after giving effect to the transactions contemplated hereby will not be, an “investment company” as such term is defined in the
Investment Company Act. 

  

	 	(viii)	Counterparty understands, agrees and acknowledges that no obligations of Dealer to it hereunder shall be entitled to the benefit of deposit insurance and that such
obligations shall not be guaranteed by any affiliate of Dealer or any governmental agency. 

  

	 	(ix)	(A) Counterparty is acting for its own account, and it has made its own independent decisions to enter into the Transaction and as to whether the Transaction is
appropriate or proper for it based upon its own judgment and upon advice from such advisers as it has deemed necessary, (B) Counterparty is not relying on any communication (written or oral) of Dealer or any of its affiliates as investment advice or
as a recommendation to enter into the Transaction (it being understood that information and explanations related to the terms and conditions of the Transaction shall not be considered investment advice or a recommendation to enter into the
Transaction) and (C) no communication (written or oral) received from Dealer or any of its affiliates shall be deemed to be an assurance or guarantee as to the expected results of the Transaction. 


 

	 	(x)	Without limiting the generality of Section 13.1 of the Equity Definitions, Counterparty acknowledges that Dealer is not making any representations or warranties with
respect to the treatment of the Transaction under ASC Topic 260, Earnings Per Share, ASC Topic 815, Derivatives and Hedging, ASC Topic 480, Distinguishing Liabilities from Equity and ASC Topic 815-40, Derivatives and Hedging – Contracts in
Entity’s Own Equity (or any successor issue statements), or under any other accounting guidance. 

  

	 	(xi)	Counterparty is not entering into the Transaction and will not make any election hereunder or under the Convertible Notes for the purpose of (i) creating actual or
apparent trading activity in the Shares (or any security convertible into or exchangeable for the Shares) or (ii) raising or depressing or otherwise manipulating the price of the Shares (or any security convertible into or exchangeable for the
Shares), in either case in violation of the U.S. Securities Exchange Act of 1934, as amended (the “Exchange Act”). 

  

	 	(xii)	Counterparty’s filings under the Exchange Act and other applicable securities laws that are required to be filed have been filed and when considered as a whole
(with the more recent such reports and documents deemed to amend inconsistent statements contained in any earlier such reports and documents), as of the date of this representation, do not contain any untrue statement of material fact or any
omission of a material fact required to be stated therein or necessary to make the statements made therein, in the light of the circumstances under which they were made, not misleading. 


 

	 	(xiii)	The Transaction, and any repurchase of the Shares by Counterparty in connection with the Transaction, has been approved by Counterparty’s board of directors
(including engaging in derivative transactions) and any such repurchase has been, or shall when so required be, publicly disclosed in its periodic filings under the Exchange Act and its financial statements and notes thereto.



  
 13 










	 	(xiv)	No state or local (including non-U.S. jurisdictions) or non-U.S. federal law, rule, regulation or regulatory order applicable to the Shares or the Issuer would give
rise to any reporting, consent, registration or other requirement (including without limitation a requirement to obtain prior approval from any person or entity) as a result of Dealer or its affiliates having the power to vote, owning or holding
(however defined) Shares. 

  

	 	(xv)	Counterparty shall deliver to Dealer on the Effective Date an opinion of counsel, dated as of such date and reasonably acceptable to Dealer in form and substance, with
respect to the matters set forth in Section 3(a) of the Agreement and such other matters as Dealer may reasonably request. 


Miscellaneous: 

Set-Off. Each party waives any and all rights it may have to set off obligations arising under the Agreement and the Transaction
against other obligations between the parties, whether arising under any other agreement, applicable law or otherwise. 

Qualified Financial Contracts. It is the intention of the parties that, in respect of Counterparty, (a) the Transaction shall
constitute a “qualified financial contract” within the meaning of 12 U.S.C. Section 1821(e)(8)(D)(i) and (b) a Non-defaulting Party’s rights under Sections 5 and 6 of the Agreement constitute rights of the kind referred to in 12
U.S.C. Section 1821(e)(8)(A). 
 Method of Delivery. Whenever delivery of funds or other assets is required hereunder by
or to Counterparty, such delivery shall be effected through Agent. In addition, all notices, demands and communications of any kind relating to the Transaction between Dealer and Counterparty shall be transmitted exclusively through Agent.

 Staggered Settlement. If upon advice of counsel with respect to applicable legal and regulatory requirements, including
any requirements relating to Dealer’s hedging activities hereunder, Dealer reasonably determines that it would not be advisable to deliver, or to acquire Shares to deliver, any or all of the Shares to be delivered by Dealer on the relevant
Settlement Date, Dealer may, by notice to Counterparty on or prior to any Settlement Date on which Dealer would be required to deliver Shares hereunder (a “Nominal Settlement Date”), elect to deliver such Shares on two or more dates
(each, a “Staggered Settlement Date”) or at two or more times on the Nominal Settlement Date as follows: (i) in such notice, Dealer will specify to Counterparty the related Staggered Settlement Dates (each of which will be on or
prior to such Nominal Settlement Date, but not prior to the beginning of the related “Conversion Period”) or delivery times and how it will allocate the Shares it is required to deliver under “Settlement” above among the
Staggered Settlement Dates or delivery times; and (ii) the aggregate number of Shares that Dealer will deliver to Counterparty hereunder on all such Staggered Settlement Dates and delivery times will equal the number of Shares that Dealer would
otherwise be required to deliver on such Nominal Settlement Date. 
 Additional Termination Events. 

 

	 	(i)	The occurrence of an “Event of Default” with respect to Counterparty under the terms of the Convertible Notes as set forth in Section 5.01 of the Supplemental
Indenture that results in the Convertible Notes becoming or being declared due and payable pursuant to the Indenture shall constitute an Additional Termination Event applicable to the Transaction and, with respect to such Additional Termination
Event, (x) Counterparty shall be deemed to be the sole Affected Party, (y) the Transaction shall be the sole Affected Transaction and (z) Dealer may designate an Exchange Business Day as an Early Termination Date pursuant to Section 6(b) of the
Agreement (which Exchange Business Day shall be on or as promptly as reasonably practicable after the occurrence of such acceleration). 

  

	 	(ii)	 Promptly following, but in no event later than the fifth Exchange Business Day after, any repurchase and cancellation of Convertible Notes (whether
pursuant to Section 9.01 of the Supplemental Indenture, Section 2.07 of the Supplemental Indenture or otherwise), Counterparty shall notify Dealer in writing of such repurchase and cancellation and the aggregate principal amount of Convertible Notes
so repurchased and 



  
 14 










	 	
cancelled (any such notice, a “Repurchase Notice”); provided that such Repurchase Notice shall contain an acknowledgement by Counterparty of its responsibilities under
applicable securities laws, and in particular Section 9 and 10(b) of the Exchange Act and the rules and regulations thereunder, in respect of such repurchase and the delivery of such Repurchase Notice. Notwithstanding anything to the contrary in
this Confirmation, the receipt by Dealer from Counterparty of any Repurchase Notice, within the applicable time period set forth in the preceding sentence and containing the acknowledgement set forth in the preceding proviso, shall constitute an
Additional Termination Event as provided in this clause (ii). Upon receipt of any such Repurchase Notice, Dealer shall designate an Exchange Business Day following receipt of such Repurchase Notice (which Exchange Business Day shall be within a
commercially reasonable period of time after the related settlement date for the repurchase of such Convertible Notes) as an Early Termination Date with respect to the portion of this Transaction corresponding to a number of Note Hedging Units (the
“Repurchase Note Hedging Units”) equal to the lesser of (A) the product of (1) the Applicable Percentage and (2) the aggregate principal amount of such Convertible Notes specified in such Repurchase Notice, divided by USD 1,000 and
(B) the Number of Note Hedging Units as of the date Dealer designates such Early Termination Date and, as of such date, the Number of Note Hedging Units shall be reduced by the number of Repurchase Note Hedging Units. Any payment hereunder with
respect to such termination shall be calculated pursuant to Section 6 of the Agreement as if (1) an Early Termination Date had been designated in respect of a Transaction having terms identical to this Transaction and a Number of Note Hedging Units
equal to the number of Repurchase Note Hedging Units, (2) Counterparty were the sole Affected Party with respect to such Additional Termination Event and (3) the terminated portion of the Transaction were the sole Affected Transaction.


  

	 	(iii)	 Notwithstanding anything to the contrary in this Confirmation, the receipt by Dealer from Counterparty, within the applicable time period set forth
under “Notice of Exercise” above, of any Notice of Exercise in respect of Note Hedging Units that relate to Make-Whole Convertible Notes shall constitute an Additional Termination Event as provided in this clause (iii). Upon receipt of any
such Notice of Exercise, Dealer shall designate an Exchange Business Day following such Additional Termination Event (which Exchange Business Day shall be within a commercially reasonable period of time after the related settlement date for such
Make-Whole Convertible Notes) as an Early Termination Date with respect to the portion of this Transaction corresponding to a number of Note Hedging Units (the “Make-Whole Note Hedging Units”) equal to the lesser of (A) the product
of (1) the Applicable Percentage and (2) the aggregate principal amount of such Make-Whole Convertible Notes specified in such Exercise Notice, divided by USD 1,000 and (B) the Number of Note Hedging Units as of the date Dealer designates such Early
Termination Date and, as of such date, the Number of Note Hedging Units shall be reduced by the number of Make-Whole Note Hedging Units. Any payment hereunder with respect to such termination (the “Make-Whole Unwind Payment”) shall
be calculated pursuant to Section 6 of the Agreement as if (1) an Early Termination Date had been designated in respect of a Transaction having terms identical to this Transaction and a Number of Note Hedging Units equal to the number of Make-Whole
Note Hedging Units, (2) Counterparty were the sole Affected Party with respect to such Additional Termination Event and (3) the terminated portion of the Transaction were the sole Affected Transaction (and, for the avoidance of doubt, in determining
the amount payable pursuant to Section 6 of the Agreement, the Calculation Agent shall not take into account any Fundamental Change Adjustment); provided that the amount of cash deliverable in respect of such early termination by Dealer to
Counterparty shall not be greater than the excess of (x) (I) the number of Make-Whole Note Hedging Units multiplied by (II) the “Conversion Rate” (after taking into account any applicable Fundamental Change Adjustment) multiplied by
(III) the Applicable Limit Price on the applicable Settlement Date determined by the Calculation Agent in good faith and in a commercially reasonable manner over (y) the product of USD 1,000 and the number of such Make-Whole Note Hedging Units,
as determined by the Calculation Agent in a commercially reasonable manner. If Counterparty has (or is deemed to have) specified a Cash Percentage that is less than 100% in the Notice of Exercise relating to any Make-Whole Note Hedging Units, then
in lieu of paying the Make-Whole Unwind Payment as set forth above, Dealer 



  
 15 










	 	
shall (A) pay to Counterparty an amount of cash equal to (1) such Cash Percentage, multiplied by (2) such Make-Whole Unwind Payment, and (B) deliver to Counterparty a number of Shares equal to
(1) 100% minus such Cash Percentage, multiplied by (2) such Make-Whole Unwind Payment, divided by (3) a price per Share determined by the Calculation Agent in good faith and in a commercially reasonable manner, in each case, on the date such
Make-Whole Unwind Payment would otherwise be due pursuant to the terms of the Agreement and this Confirmation (or within a commercially reasonable period of time thereafter, as determined by Dealer taking into account existing liquidity conditions
and Dealer’s hedging and hedge unwind activity or settlement activity in connection with such payment and delivery). 

 Counterparty agrees that it will promptly cancel any repurchased Convertible Notes pursuant to Section 2.06 of the Supplemental Indenture. 

For the avoidance of doubt, the provisions set forth below under “Alternative Calculations and Dealer Payment on Early Termination
and on Certain Extraordinary Events,” including and subject to the conditions and limitations set forth therein, shall apply to any Dealer Payment Obligation amount resulting from an Additional Termination Event set forth in clause (i) or (ii)
above. 
 Disposition of Hedge Shares. Counterparty hereby agrees that if, in the good faith reasonable judgment of Dealer based on the
advice of counsel, the Shares (the “Hedge Shares”) acquired by Dealer or any of its affiliates (collectively for the purposes of this paragraph only, “Dealer”) for the purpose of hedging its obligations pursuant to
the Transaction cannot be sold in the public market by Dealer without registration under the Securities Act, Counterparty shall, at its election: (i) in order to allow Dealer to sell the Hedge Shares in a registered offering, make available to
Dealer an effective registration statement under the Securities Act to cover the resale of such Hedge Shares and (A) enter into an agreement, in form and substance satisfactory to Dealer, substantially in the form of an underwriting agreement
for a registered offering of substantially similar size, (B) provide accountant’s “comfort” letters in customary form for registered offerings of equity securities of substantially similar size, (C) provide disclosure
opinions of nationally recognized outside counsel to Counterparty reasonably acceptable to Dealer, (D) provide other customary opinions, certificates and closing documents customary in form for registered offerings of equity securities of
substantially similar size and (E) afford Dealer a reasonable opportunity to conduct a “due diligence” investigation with respect to Counterparty customary in scope for underwritten offerings of equity securities of substantially
similar size; provided, however, that if Dealer, in its sole discretion, is not satisfied with access to due diligence materials, the results of its due diligence investigation, or the procedures and documentation for the registered
offering referred to above, then clause (ii) or clause (iii) of this paragraph shall apply at the election of Counterparty; (ii) in order to allow Dealer to sell the Hedge Shares in a private placement, enter into a private placement
agreement substantially similar to private placement purchase agreements customary for private placements of equity securities of substantially similar size, in form and substance satisfactory to Dealer, including customary representations,
covenants, blue sky and other governmental filings and/or registrations, indemnities to Dealer, due diligence rights (for Dealer or any designated buyer of the Hedge Shares from Dealer), opinions and certificates and such other documentation as is
customary for private placements agreements for private placements of equity securities of substantially similar size, all reasonably acceptable to Dealer (in which case, the Calculation Agent shall make any adjustments to the terms of the
Transaction that are necessary, in its commercially reasonable determination, to compensate Dealer for any discount from the public market price of the Shares incurred on the sale of Hedge Shares in a private placement); or (iii) purchase the
Hedge Shares from Dealer at the VWAP Price on such Exchange Business Days, and in the amounts, requested by Dealer. “VWAP Price” means, on any Exchange Business Day, the per Share volume-weighted average price as displayed under the
heading “Bloomberg VWAP” on Bloomberg page MRX.N <equity> AQR (or any successor thereto) in respect of the period from 9:30 a.m. to 4:00 p.m. (New York City time) on such Exchange Business Day (or if such volume-weighted average
price is unavailable, or is, in the Calculation Agent’s reasonable discretion, erroneous, the market value of one Share on such Exchange Business Day, as determined by the Calculation Agent using, if practicable, a volume-weighted method). This
paragraph shall survive the termination, expiration or early unwind of the Transaction. 

  
 16 









 Status of Claims in Bankruptcy. Dealer acknowledges and agrees that this Confirmation is not intended
to convey to Dealer rights with respect to the Transaction that are senior to the claims of common stockholders in any U.S. bankruptcy proceedings of Counterparty; provided that nothing herein shall limit or shall be deemed to limit
Dealer’s right to pursue remedies in the event of a breach by Counterparty of its obligations and agreements with respect to the Transaction other than during Counterparty’s bankruptcy; provided, further, that nothing
herein shall limit or shall be deemed to limit Dealer’s rights in respect of any transactions other than the Transaction. 
 No
Collateral. Notwithstanding any provision of this Confirmation, the Agreement, Equity Definitions, or any other agreement between the parties to the contrary, the obligations of Counterparty under the Transaction are not secured by any
collateral. 
 Securities Contract; Swap Agreement. The parties hereto agree and acknowledge that Dealer is a “financial
institution,” “swap participant” and “financial participant” within the meaning of Sections 101(22), 101(53C) and 101(22A) of the Bankruptcy Code. The parties hereto further agree and acknowledge (A) that this Confirmation
is (i) a “securities contract,” as such term is defined in Section 741(7) of the Bankruptcy Code, with respect to which each payment and delivery hereunder or in connection herewith is a “termination value,” “payment
amount” or “other transfer obligation” within the meaning of Section 362 of the Bankruptcy Code and a “settlement payment” or a “transfer” within the meaning of Section 546 of the Bankruptcy Code, and (ii) a
“swap agreement,” as such term is defined in Section 101(53B) of the Bankruptcy Code, with respect to which each payment and delivery hereunder or in connection herewith is a “termination value,” a “payment amount” or
“other transfer obligation” within the meaning of Section 362 of the Bankruptcy Code and a “transfer” within the meaning of Section 546 of the Bankruptcy Code, and (B) that Dealer is entitled to the protections afforded by, among
other sections, Section 362(b)(6), 362(b)(17), 362(b)(27), 362(o), 546(e), 546(g), 546(j), 548(d)(2), 555, 560 and 561 of the Bankruptcy Code. 

Repurchase Notices. Counterparty shall, on any day on which Counterparty effects any repurchase of Shares, provide Dealer with a written notice of
such repurchase (a “Repurchase Notice”) on such day if, following such repurchase, the Unit Equity Percentage as determined on such day is greater by 0.5% or more than the Unit Equity Percentage included in the immediately preceding
Repurchase Notice (or, in the case of the first such Repurchase Notice, greater by 0.5% or more than the Unit Equity Percentage as of the date hereof). The “Unit Equity Percentage” as of any day is the fraction, expressed as a
percentage, (i) the numerator of which is the sum of (A) the product of the number of Note Hedging Units and the Note Hedging Unit Entitlement and (B) the number of Shares underlying any other call option transaction between Dealer as
seller and Counterparty as buyer, and (ii) the denominator of which is the number of Shares outstanding on such day. Counterparty agrees to indemnify and hold harmless Dealer and its affiliates and their respective officers, directors, employees,
advisors, agents and controlling persons (each, a “Section 16 Indemnified Person”) from and against any and all losses (including losses relating to Dealer’s hedging activities as a consequence of becoming a Section 16
“insider”, including without limitation, any forbearance from hedging activities or cessation of hedging activities and any losses in connection therewith with respect to the Transaction), claims, damages, judgments, liabilities and
reasonable expenses (including reasonable attorney’s fees), joint or several, to which a Section 16 Indemnified Person may become subject, as a result of Counterparty’s failure to provide Dealer with a Repurchase Notice on the day and in
the manner specified in this paragraph, and to reimburse, within 30 days upon written request, each of such Section 16 Indemnified Persons for any reasonable legal or other expenses incurred in connection with investigating, preparing for, providing
testimony or other evidence in connection with or defending any of the foregoing. If any suit, action, proceeding (including any governmental or regulatory investigation), claim or demand shall be brought or asserted against the Section 16
Indemnified Person, such Section 16 Indemnified Person shall promptly notify Counterparty in writing, and Counterparty, upon request of the Section 16 Indemnified Person, shall retain counsel reasonably satisfactory to the Section 16 Indemnified
Person to represent the Section 16 Indemnified Person and any others Counterparty may designate in such proceeding and shall pay the reasonable fees and expenses of such counsel related to such proceeding. Counterparty shall not be liable for any
settlement of any proceeding effected without its written consent, but if settled with such consent or if there be a final judgment for the plaintiff, Counterparty agrees to indemnify any Section 16 Indemnified Person from and against any loss or
liability by reason of such settlement or judgment. Counterparty shall not, without the prior written consent of the Section 16 Indemnified Person, effect any settlement of any pending or threatened proceeding in respect of which any Section 16
Indemnified Person is or 

  
 17 









 
could have been a party and indemnity could have been sought hereunder by such Section 16 Indemnified Person, unless such settlement includes an unconditional release of such Section 16
Indemnified Person from all liability on claims that are the subject matter of such proceeding on terms reasonably satisfactory to such Section 16 Indemnified Person. If the indemnification provided for in this paragraph is unavailable to a Section
16 Indemnified Person or insufficient in respect of any losses, claims, damages or liabilities referred to therein, then Counterparty, in lieu of indemnifying such Section 16 Indemnified Person thereunder, shall contribute to the amount paid or
payable by such Section 16 Indemnified Person as a result of such losses, claims, damages or liabilities. The remedies provided for in this paragraph are not exclusive and shall not limit any rights or remedies that may otherwise be available to any
Section 16 Indemnified Person at law or in equity. The indemnity and contribution agreements contained in this paragraph shall remain operative and in full force and effect regardless of the termination of the Transaction. 

Alternative Calculations and Dealer Payment on Early Termination and on Certain Extraordinary Events. If Dealer owes Counterparty any amount in
connection with the Transaction pursuant to Sections 12.2, 12.3 (and “Consequences of Merger Events” above), 12.6, 12.7 or 12.9 of the Equity Definitions (except in the case of an Extraordinary Event that (x) is within
Counterparty’s control or (y) as a result of which the Shares have changed into cash) or pursuant to Section 6(d)(ii) of the Agreement (except in the case of an Event of Default in which Counterparty is the Defaulting Party or a
Termination Event in which Counterparty is the Affected Party, other than an Event of Default or a Termination Event that resulted from an event or events outside Counterparty’s control) (a “Dealer Payment Obligation”),
Counterparty shall have the right, in its sole discretion, to require Dealer to satisfy any such Dealer Payment Obligation by delivery of Termination Delivery Units (as defined below) by (A) giving irrevocable telephonic notice to Dealer,
confirmed in writing within one Scheduled Trading Day, between the hours of 9:00 a.m. and 4:00 p.m. New York time on the Early Termination Date or other date the transaction is terminated, as applicable (“Notice of Dealer Termination
Delivery”) and (B) remaking the representation set forth under “No Material Non-Public Information” below on the date of such notice; provided that if Counterparty does not validly so elect (or is not permitted to
elect) to require Dealer to satisfy its Dealer Payment Obligation by delivery of Termination Delivery Units, Dealer shall have the right, in its sole discretion, to elect to satisfy its Dealer Payment Obligation by delivery of Termination Delivery
Units. Within a commercially reasonable period of time following receipt of a Notice of Dealer Termination Delivery or delivery by Dealer of notice of its election to satisfy the Dealer Payment Obligation by delivery of Termination Delivery Units,
Dealer shall deliver to Counterparty a number of Termination Delivery Units having a cash value equal to the amount of such Dealer Payment Obligation (as determined by the Calculation Agent in a commercially reasonable manner). If the provisions set
forth in this paragraph are applicable, the provisions of Sections 9.8, 9.9, 9.11 (modified as described above) and 9.12 of the Equity Definitions shall be applicable, except that all references to “Shares” shall be read as references
to “Termination Delivery Units”. In addition, notwithstanding anything to the contrary in the Equity Definitions, Dealer may, in whole or in part, deliver securities comprising Termination Delivery Units in certificated form to
Counterparty in lieu of delivery through the Clearance System. 
 “Termination Delivery Unit” means one Share or, if the Shares
have changed into cash or any other property or the right to receive cash or any other property as the result of an Insolvency, Nationalization or Merger Event, a unit consisting of the number or amount of each type of property received by a holder
of one Share (without consideration of any requirement to pay cash or other consideration in lieu of fractional amounts of any securities) in such Insolvency, Nationalization or Merger Event, as determined by the Calculation Agent. If such
Insolvency, Nationalization or Merger Event involves a choice of consideration to be received by holders, the Calculation Agent shall determine the composition of such consideration in its commercially reasonable discretion. 

No Material Non-Public Information. Counterparty represents and warrants to Dealer that it is not aware of any material nonpublic information
concerning itself, the Shares or option contracts related to the Shares. 
 Right to Extend. Dealer may postpone any potential Exercise
Date or Settlement Date or postpone or extend any other date of valuation or delivery with respect to some or all of the relevant Note Hedging Units (in which event the Calculation Agent shall make appropriate adjustments to the Settlement Amount
for such Note Hedging Units), if Dealer determines, in its reasonable discretion based on the advice of counsel (in the case of clause (a) or sub-clause (b)(ii) below) or in its commercially reasonable discretion (in the case of sub-clause (b)(i)
below), 

  
 18 









 
that (a) a Regulatory Disruption has occurred or (b) such extension is reasonably necessary or appropriate to (i) preserve Dealer’s hedging or hedge unwind activity hereunder in light of
existing liquidity conditions (but only if there is a material decrease in liquidity relative to Dealer’s expectations on the Trade Date) or (ii) enable Dealer to effect purchases of Shares in connection with its hedging, hedge unwind or
settlement activity hereunder in a manner that would, if Dealer were the Issuer or an affiliated purchaser of the Issuer, be in compliance with applicable legal, regulatory or self-regulatory requirements, or with related policies and procedures
applicable to Dealer. “Regulatory Disruption” shall mean any event that Dealer determines makes it appropriate with regard to any legal, regulatory or self-regulatory requirements or related policies and procedures (whether or not such
requirements, policies or procedures are imposed by law or have been voluntarily adopted by Dealer), for Dealer to refrain from or decrease any market activity in connection with the Transaction. Notwithstanding anything to the contrary, in the case
of a postponement pursuant to sub-clause (b)(i) above, no such Exercise Date or Settlement Date or other date of valuation or delivery may be postponed or added more than 30 Scheduled Trading Days after the original Exercise Date or Settlement Date
or other date of valuation or delivery, as the case may be. 
 Transfer or Assignment. Counterparty may not transfer any of its rights or
obligations under the Transaction without the prior written consent of Dealer not to be unreasonably withheld. For the avoidance of doubt, Dealer may condition its consent on any of the following, without limitation: (i) the receipt by Dealer of
opinions and documentation reasonably satisfactory to Dealer in connection with such transfer, (ii) such transfer being effected on terms reasonably satisfactory to Dealer with respect to any legal and regulatory requirements relevant to Dealer,
(iii) the transferee being a United States person (as defined in the Internal Revenue Code of 1986, as amended), (iv) that, in Dealer’s reasonable determination, Dealer will not be required, as a result of such transfer, to pay the transferee
an amount under Section 2(d)(i)(4) of the Agreement greater than the amount, if any, that Dealer would have been required to pay to Counterparty in the absence of such transfer, (v) that, in Dealer’s reasonable determination, no Event of
Default, Potential Event of Default or Termination Event will occur as a result of such transfer and (vi) that Counterparty will continue to be obligated to provide notices hereunder relating to the Convertible Notes and will continue to be
obligated under the provisions set forth under “Disposition of Hedge Shares” and “Repurchase Notices” herein. In addition, Dealer may not, without the consent of Counterparty (such consent not to be unreasonably withheld),
transfer or assign all or a portion of its Note Hedging Units hereunder except to any affiliate of Dealer (x) that has, at the time of such transfer or assignment, a rating for its long term, unsecured and unsubordinated indebtedness that is equal
to or better than Dealer’s credit rating, or (y) whose obligation hereunder will be guaranteed, pursuant to the terms of a customary guarantee in a form used by Dealer generally for similar transactions, by Dealer. Notwithstanding the
foregoing, it shall be a further condition to a transfer or assignment by Dealer without Counterparty’s consent that such transfer or assignment would not result in a deemed exchange by Counterparty of the transferred or assigned portion of the
Transaction for a modified transaction that differs materially in kind or extent for U.S. federal income tax purposes. 
 If (a) at any time (1)
the Section 16 Equity Percentage exceeds 8%, (2) the Unit Equity Percentage exceeds 14.5% or (3) Dealer, Dealer Group (as defined below) or any person whose ownership position would be aggregated with that of Dealer or Dealer Group (Dealer,
Dealer Group or any such person, a “Dealer Person”) under any federal, state or local (including non-U.S.) laws, rules, regulations or regulatory orders, or any organizational documents or contracts of Counterparty that are, in each
case, applicable to ownership of Shares (“Applicable Restrictions”), owns, beneficially owns, constructively owns, controls, holds the power to vote or otherwise meets a relevant definition of ownership, or could be reasonably
viewed as meeting any of the foregoing, in excess of a number of Shares equal to (x) the number of Shares that would give rise to reporting, registration, filing or notification obligations or other requirements (including obtaining prior approval
by a state, federal or non-U.S. regulator) of a Dealer Person, or could result in an adverse effect on a Dealer Person (except for any filings of Schedule 13D or Schedule 13G under the Exchange Act or any other filing obligations applicable as of
the date hereof), under Applicable Restrictions, as determined by Dealer in its reasonable discretion, and with respect to which such requirements have not been met or the relevant approval has not been received minus (y) 1% of the number of
Shares outstanding on the date of determination (either such condition described in clause (1), (2) or (3), an “Excess Ownership Position”), and (b) Dealer is unable, after commercially reasonable efforts, to effect a transfer or
assignment on pricing and terms and within a time period reasonably acceptable to it of all or a portion of this Transaction pursuant to the preceding paragraph such that an Excess Ownership Position no


  
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longer exists (it being understood and agreed that, if an Excess Ownership Position exists, the condition to transfer or assignment set forth in the last sentence of the preceding paragraph shall
not apply), Dealer may designate any Scheduled Trading Day as an Early Termination Date with respect to a portion (the “Terminated Portion”) of this Transaction, such that an Excess Ownership Position no longer exists following such
partial termination. In the event that Dealer so designates an Early Termination Date with respect to a portion of this Transaction, a payment shall be made pursuant to Section 6 of the Agreement as if (i) an Early Termination Date had been
designated in respect of a Transaction having terms identical to this Transaction and a Number of Note Hedging Units equal to the Terminated Portion, (ii) Counterparty shall be the sole Affected Party with respect to such partial termination and
(iii) such Transaction shall be the only Terminated Transaction (and, for the avoidance of doubt, the provisions set forth under the caption “Alternative Calculations and Dealer Payment on Early Termination and on Certain Extraordinary
Events” shall apply to any amount that is payable by Dealer to Counterparty pursuant to this sentence). The “Section 16 Equity Percentage” as of any day is the fraction, expressed as a percentage, (A) the numerator of which is
the number of Shares that Dealer and any of its affiliates subject to aggregation with Dealer for purposes of the “beneficial ownership” test under Section 13 of the Exchange Act and all persons who may form a “group” (within the
meaning of Rule 13d-5(b)(1) under the Exchange Act) with Dealer (collectively, “Dealer Group”) “beneficially own” (within the meaning of Section 13 of the Exchange Act) without duplication on such day (or to the extent
that the equivalent calculation under Section 16 of the Exchange Act and the rules and regulations thereunder results in a higher number, such number) and (B) the denominator of which is the number of Shares outstanding on such day. 

Designation by Dealer. Notwithstanding any other provision in this Confirmation to the contrary requiring or allowing Dealer to purchase, sell,
receive or deliver any shares or other securities to or from Counterparty, Dealer may designate any of its affiliates to purchase, sell, receive or deliver such shares or other securities and otherwise to perform Dealer’s obligations in respect
of the Transaction and any such designee may assume such obligations. Dealer shall be discharged of its obligations to Counterparty to the extent of any such performance. 
 Matters Related to Agent. Each party agrees and acknowledges that (i) Agent acts solely as agent on a disclosed basis with respect to the Transaction, and (ii) Agent has no obligation, by guaranty,
endorsement or otherwise, with respect to the obligations of either Counterparty or Dealer hereunder, either with respect to the delivery of cash or Shares, either at the beginning or the end of the Transaction. In this regard, each of Counterparty
and Dealer acknowledges and agrees to look solely to the other for performance hereunder, and not to Agent. 
 Severability; Illegality.
Notwithstanding anything to the contrary in the Agreement, if compliance by either party with any provision of the Transaction would be unenforceable or illegal, (a) the parties shall negotiate in good faith to resolve such unenforceability or
illegality in a manner that preserves the economic benefits of the transactions contemplated hereby and (b) the other provisions of the Transaction shall not be invalidated, but shall remain in full force and effect. 

Waiver of Jury Trial. EACH PARTY WAIVES, TO THE FULLEST EXTENT PERMITTED BY APPLICABLE LAW, ANY RIGHT IT MAY HAVE TO A TRIAL BY JURY IN RESPECT OF
ANY SUIT, ACTION OR PROCEEDING RELATING TO THE TRANSACTION. EACH PARTY (I) CERTIFIES THAT NO REPRESENTATIVE, AGENT OR ATTORNEY OF THE OTHER PARTY HAS REPRESENTED, EXPRESSLY OR OTHERWISE, THAT SUCH OTHER PARTY WOULD NOT, IN THE EVENT OF SUCH A
SUIT, ACTION OR PROCEEDING, SEEK TO ENFORCE THE FOREGOING WAIVER AND (II) ACKNOWLEDGES THAT IT AND THE OTHER PARTY HAVE BEEN INDUCED TO ENTER INTO THE TRANSACTION, AS APPLICABLE, BY, AMONG OTHER THINGS, THE MUTUAL WAIVERS AND CERTIFICATIONS
PROVIDED HEREIN. 
 Wall Street Transparency and Accountability Act. In connection with Section 739 of the Wall Street Transparency and
Accountability Act of 2010 (“WSTAA”), the parties hereby agree that neither the enactment of WSTAA or any regulation under the WSTAA, nor any requirement under WSTAA or an amendment made by WSTAA, shall limit or otherwise impair either
party’s otherwise applicable rights to terminate, renegotiate, modify, amend or supplement this Confirmation or the Agreement, as applicable, arising from a termination event, force majeure, illegality, increased costs, regulatory change or
similar event under this Confirmation, the Equity Definitions incorporated herein, or the Agreement (including, but not limited to, rights arising from Change in Law, Hedging Disruption, Increased Cost of Hedging, an Excess Ownership Position, or
Illegality (as defined in the Agreement)). 

  
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 Agreements and Acknowledgements Regarding Hedging. Counterparty understands, acknowledges and agrees
that: (A) at any time on and prior to the Expiration Date, Dealer and its affiliates may buy or sell Shares or other securities or buy or sell options or futures contracts or enter into swaps or other derivative securities in order to adjust
its hedge position with respect to the Transaction; (B) Dealer and its affiliates also may be active in the market for Shares other than in connection with hedging activities in relation to the Transaction; (C) Dealer shall make its own
determination as to whether, when or in what manner any hedging or market activities in securities of Issuer shall be conducted and shall do so in a manner that it deems appropriate to hedge its price and market risk with respect to the “Daily
VWAP”; and (D) any market activities of Dealer and its affiliates with respect to Shares may affect the market price and volatility of Shares, as well as the “Daily VWAP”, each in a manner that may be adverse to Counterparty.

 Early Unwind. In the event the sale of the “Firm Securities” (as defined in the Underwriting Agreement) is not consummated
with the underwriters thereof for any reason, other than in cases involving breach of the Underwriting Agreement by Dealer or its affiliate, by the close of business in New York on May 23, 2012 (or such later date as agreed upon by the parties)
(May 23, 2012 or such later date as agreed upon being the “Early Unwind Date”), the Transaction shall automatically terminate (the “Early Unwind”) on the Early Unwind Date and (a) the Transaction and all of the
respective rights and obligations of Dealer and Counterparty under the Transaction shall be cancelled and terminated and (b) each party shall be released and discharged by the other party from and agrees not to make any claim against the other
party with respect to any obligations or liabilities of the other party arising out of and to be performed in connection with the Transaction either prior to or after the Early Unwind Date. Dealer and Counterparty represent and acknowledge to the
other that, upon an Early Unwind, all obligations with respect to the Transaction shall be deemed fully and finally discharged. 
 Payment by
Counterparty. In the event that, following payment of the Premium, (i) an Early Termination Date occurs or is designated with respect to the Transaction as a result of a Termination Event or an Event of Default (other than an Event of
Default or Termination Event within Counterparty’s control) and, as a result, Counterparty owes to Dealer an amount calculated under Section 6(e) of the Agreement, or (ii) Counterparty owes to Dealer any amount under
“Consequences of Merger Events” above (other than as a result of a Merger Event that resulted from an event or events within Counterparty’s control), such amount shall be deemed to be zero. 

Part 2(b) of the ISDA Schedule – Payee Representation. For the purpose of Section 3(f) of this Agreement, Counterparty makes the
following representation to Dealer: 
 Counterparty is a corporation established under the laws of the State of Delaware and is a “United
States person” (as that term is defined in Section 7701(a)(30) of the Code). 
 For the purpose of Section 3(f) of this Agreement,
Dealer makes the following representation to Counterparty: 
  

	 	(A)	Each payment received or to be received by it in connection with this Agreement is effectively connected with its conduct of a trade or business within the United
States; and 

  

	 	(B)	It is a “foreign person” (as that term is used in Section 1.6041-4(a)(4) of the United States Treasury Regulations) for United States federal income tax
purposes. 

 Part 3(a) of the ISDA Schedule – Tax Forms: 

 

					
	Party Required to Deliver Document	  	Form/Document/Certificate	  	Date by which to be Delivered
	 	 	 
	Counterparty	  	A complete and duly executed United States Internal Revenue Service Form W-9 (or successor
thereto.)	  	(i) Upon execution and delivery of this Agreement; (ii) promptly upon reasonable demand by
Dealer; and (iii) promptly upon learning that any such Form previously provided by Counterparty has become obsolete or incorrect.
	 	 	 
	Dealer	  	A complete and duly executed United States Internal Revenue Service Form W-8ECI (or successor
thereto).	  	(i) Upon execution and delivery of this Agreement; (ii) promptly upon reasonable demand by
Counterparty; and (iii) promptly upon learning that any such Form previously provided by Dealer has become obsolete or incorrect.


  
 21 









 Governing Law; Jurisdiction: THIS CONFIRMATION AND ANY CLAIM, CONTROVERSY OR DISPUTE
ARISING UNDER OR RELATED TO THIS CONFIRMATION SHALL BE GOVERNED BY THE LAWS OF THE STATE OF NEW YORK. THE PARTIES HERETO IRREVOCABLY SUBMIT TO THE EXCLUSIVE JURISDICTION OF THE COURTS OF THE STATE OF NEW YORK AND THE UNITED STATES COURT FOR THE
SOUTHERN DISTRICT OF NEW YORK IN CONNECTION WITH ALL MATTERS RELATING HERETO AND WAIVE ANY OBJECTION TO THE LAYING OF VENUE IN, AND ANY CLAIM OF INCONVENIENT FORUM WITH RESPECT TO, THESE COURTS. 

Contact information. For purposes of the Agreement (unless otherwise specified in the Agreement), the addresses for notice to the parties shall
be: 
  

	(a)	Counterparty 

 Medicis
Pharmaceutical Corporation 
 7720 North Dobson Road 
 Scottsdale, Arizona 85256 
 Attention: Richard D. Peterson 

Fax: (480) 291-8847 
  

	(b)	Dealer 

 Deutsche Bank AG,
London Branch 
 c/o Deutsche Bank Securities Inc. 
 60 Wall Street New York, NY 10005 
 Attention: Andrew Yaeger 

Telephone: (212) 250-2717 
 Email: Andrew.Yaeger@db.com 
 with a copy to: 

Deutsche Bank AG, London Branch 
 c/o Deutsche Bank Securities Inc. 
 60 Wall Street 

New York, New York 10005 
 Attention: Faiz Khan 
 Telephone: (212) 250-0668 

Email: Faiz.Khan@db.com 

  
 22 









 This Confirmation may be executed in several counterparts, each of which shall be deemed an original but all
of which together shall constitute one and the same instrument. 
 Counterparty hereby agrees to check this Confirmation and to confirm that the
foregoing correctly sets forth the terms of the Transaction by signing in the space provided below and returning to Dealer a facsimile of the fully-executed Confirmation to Dealer at 44 113 336 2009. Originals shall be provided for your execution
upon your request. 
 We are very pleased to have executed the Transaction with you and we look forward to completing other transactions with
you in the near future. 
 Very truly yours, 
 DEUTSCHE BANK AG, LONDON BRANCH 
  

			
	By:	 	 /s/ Michael Sanderson

	Name: Michael Sanderson
	Title: Managing Director
		
	By:	 	 /s/ Dushyant Chadha

	Name: Dushyant Chadha
	Title: Managing Director

 DEUTSCHE BANK SECURITIES INC., 
 acting solely as Agent in connection with this Transaction 
  

			
	By:	 	 /s/ Michael Sanderson

	Name: Michael Sanderson
	Title: Managing Director
		
	By:	 	 /s/ Dushyant Chadha

	Name: Dushyant Chadha
	Title: Managing Director

 Counterparty hereby agrees to, accepts and confirms the terms of the foregoing as of the Trade Date. 

MEDICIS PHARMACEUTICAL CORPORATION 
  

			
	By:	 	 /s/ Richard D. Peterson

		 	Name: Richard D. Peterson
		 	Title: Executive Vice President,
		 	        Chief Financial Officer & Treasurer

 [Base Note Hedge Transaction Signature Page] 







 ANNEX A 
 The Premium for the Transaction is set forth below. 
  

			
	Premium:	  	USD 43,200,000


  
 A-1