IIB 

117TH CONGRESS 

2D SESSION H. R. 1193 

IN THE SENATE OF THE UNITED STATES 

DECEMBER 9, 2021 

Received 

MAY 25, 2022 

Read twice and referred to the Committee on Health, Education, Labor, and 

Pensions 

AN ACT 

To amend title IV of the Public Health Service Act to 

direct the Director of the National Institutes of Health, 

in consultation with the Director of the National Heart, 

Lung, and Blood Institute, to establish a program under 

which the Director of the National Institutes of Health 

shall support or conduct research on valvular heart disease, and for other purposes. 


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HR 1193 RFS

1 Be it enacted by the Senate and House of Representa2 tives of the United States of America in Congress assembled, 

3 SECTION 1. SHORT TITLE. 

4 This Act may be cited as the ‘‘Cardiovascular Ad5 vances in Research and Opportunities Legacy Act’’. 

6 SEC. 2. GRANTS FOR VALVULAR HEART DISEASE RE7 SEARCH. 

8 Subpart 2 of part C of title IV of the Public Health 

9 Service Act (42 U.S.C. 285b et seq.) is amended by insert10 ing after section 424C (42 U.S.C. 285b–7c) the following: 

11 ‘‘SEC. 424D. GRANTS FOR VALVULAR HEART DISEASE RE12 SEARCH. 

13 ‘‘(a) IN GENERAL.—The Director of the National In14 stitutes of Health, in consultation with the Director of the 

15 Institute, shall support or conduct research regarding val16 vular heart disease. 

17 ‘‘(b) SUPPORT GUIDELINES.—The distribution of 

18 funding authorized under subsection (a) may be used to 

19 pursue the following outcomes: 

20 ‘‘(1) Using precision medicine and advanced 

21 technological imaging to generate data on individ22 uals with valvular heart disease. 

23 ‘‘(2) Identifying and developing a cohort of in24 dividuals with valvular heart disease and available 

25 data. 


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HR 1193 RFS

1 ‘‘(3) Corroborating data generated through clin2 ical trials to develop a prediction model to distin3 guish individuals at high risk for sudden cardiac ar4 rest or sudden cardiac death from valvular heart dis5 ease. 

6 ‘‘(4) For other outcomes needed to acquire nec7 essary data on valvular heart disease. 

8 ‘‘(c) MITRAL VALVE PROLAPSE WORKSHOP.—Not 

9 later than one year after the date of the enactment of this 

10 section, the Director of the Institute shall convene a work11 shop composed of subject matter experts and stakeholders 

12 to identify research needs and opportunities to develop 

13 prescriptive guidelines for treatment of individuals with 

14 mitral valve prolapse. 

15 ‘‘(d) AUTHORIZATION OF APPROPRIATIONS.—For the 

16 purpose of carrying out this section, there is authorized 

17 to be appropriated $20,000,000 for each of fiscal years 

18 2022 through 2026.’’. 

19 SEC. 3. PROGRAMS OF CENTERS FOR DISEASE CONTROL 

20 AND PREVENTION. 

21 Part B of title III of the Public Health Service Act 

22 (42 U.S.C. 243 et seq.) is amended by inserting after sec23 tion 312 the following section: 


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HR 1193 RFS

1 ‘‘SEC. 312A. PREVENTION OF SUDDEN CARDIAC DEATH AS A 

2 RESULT OF VALVULAR HEART DISEASE. 

3 ‘‘(a) IN GENERAL.—The Secretary, acting through 

4 the Director of the Centers for Disease Control and Pre5 vention, may carry out projects to increase education, 

6 awareness, or diagnosis of valvular heart disease and to 

7 reduce the incidence of sudden cardiac death caused by 

8 valvular heart disease. Such projects may be carried out 

9 by the Secretary directly or through awards of grants or 

10 contracts to public or nonprofit private entities. The Sec11 retary may directly (or through such awards) provide tech12 nical assistance with respect to the planning, development, 

13 and operation of such projects. 

14 ‘‘(b) CERTAIN ACTIVITIES.—Upon availability of ap15 plicable data, projects carried out under subsection (a) 

16 may include— 

17 ‘‘(1) continuing the activities at the Division for 

18 Heart Disease and Stroke Prevention, including 

19 those related to valvular heart disease; 

20 ‘‘(2) broadening the awareness of the public 

21 concerning the risk factors for, the symptoms of, 

22 and the public health consequences of valvular heart 

23 disease; and 

24 ‘‘(3) enhancing surveillance of out-of-hospital 

25 cardiac arrests to improve patient outcomes. 


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HR 1193 RFS

1 ‘‘(c) GRANT PRIORITIZATION.—The Secretary may, 

2 in awarding grants or entering into contracts pursuant to 

3 subsection (a), give priority to entities seeking to carry 

4 out projects that target populations most impacted by val5 vular heart disease. 

6 ‘‘(d) COORDINATION OF ACTIVITIES.—The Secretary 

7 shall ensure that activities under this section are coordi8 nated, as appropriate, with other agencies of the Public 

9 Health Service that carry out activities regarding valvular 

10 heart disease. 

11 ‘‘(e) BEST PRACTICES.—The Secretary, acting 

12 through the Director of the Centers for Disease Control 

13 and Prevention, shall— 

14 ‘‘(1) collect and analyze the findings of research 

15 conducted with respect to valvular heart disease; and 

16 ‘‘(2) taking into account such findings, publish 

17 on the website of the Centers for Disease Control 

18 and Prevention best practices for physicians and 

19 other health care providers who provide care to indi20 viduals with valvular heart disease.’’. 

Passed the House of Representatives December 8, 

2021. 

Attest: CHERYL L. JOHNSON, 

Clerk. 


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