Amendment to Settlement Agreement



 EXHIBIT 10.83 
 AMENDMENT TO SETTLEMENT AGREEMENT 
 WHEREAS, on or about July 11, 2007, a settlement agreement
(the “Settlement Agreement”) was entered into among the United States of America, acting through its Department of Justice and the United States Attorney’s Office for the Eastern District of New York, the Office of Inspector General
of the Department of Health and Human Services (“HHS-OIG”), the United States Office of Personnel Management (“OPM”), and the United States Department of Defense TRICARE Management Activity (“TMA”) (collectively the
“United States”); Jazz Pharmaceuticals, Inc. (“JPI”) and Orphan Medical, Inc. (which merged in 2008 into Orphan Medical, LLC) (“Orphan”) (JPI and Orphan are collectively referred to as “Defendants”); and
Shelley Lauterbach (the “Relator”); through their authorized representatives (collectively, all of the above will be referred to as “the Parties”); 
 WHEREAS, the Settlement Agreement resolved certain claims that the United States and Relator had against Defendants regarding the marketing of the drug Xyrem, including claims under the federal False Claims Act;

 WHEREAS, in accordance with the Settlement Agreement, Defendants agreed to make payments to the United States pursuant to a schedule
annexed to the Settlement Agreement (the “Schedule”); 
 WHEREAS, the Settlement Agreement requires Defendants to make a payment to
the United States on January 15, 2009; 
 WHEREAS, due to a change in their financial condition, Defendants have requested that the
Schedule be amended so that their January 15, 2009 payment becomes due on October 15, 2009; 
 WHEREAS, following the United States
review of Defendants’ current financial condition, the United States and Relator consent to such an amendment of the Settlement Agreement; 
  


					
	 Amendment to Civil Settlement Agreement
 with Jazz Pharmaceutical, Inc/Orphan Medical
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 THEREFORE, the Parties hereby agree to the following: 
 1. The Schedule is amended as follows: Defendants’ January 15, 2009 payment to the United States is now due on October 15, 2009.

 2. Defendants and Relator represent that this Amendment is freely and voluntarily entered into without any degree of duress or compulsion
whatsoever. 
 3. The individuals signing this Amendment on behalf of Defendants represent and warrant that they are authorized by Defendants
to execute this Amendment. The individual signing this Amendment on behalf of Relator represents and warrants that he is authorized by Relator to execute this Amendment. The United States signatories represent that they are signing this Amendment in
their official capacities and that they are authorized to execute this Amendment. 
 4. This Amendment may be executed in counterparts, each
of which constitutes an original and all of which constitute one and the same Amendment. 
 5. This Amendment is binding on Defendants’
successors, transferees, heirs, and assigns. 
 6. This Amendment is binding on Relator’s successors, transferees, heirs, and assigns.

 7. All Parties consent to the United States’ disclosure of this Amendment, and information about this Amendment, to the public.

 8. This Amendment is effective on the date of signature of the last signatory to the Amendment (the “Effective Date of this
Amendment”). Facsimiles of signatures shall constitute acceptable, binding signatures for purposes of this Amendment. 
  


					
	 Amendment to Civil Settlement Agreement
 with Jazz Pharmaceutical, Inc/Orphan Medical
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 THE UNITED STATES OF AMERICA 
  

									
		 		 	BENTON J. CAMPBELL
		 		 	United States Attorney
		 		 	Eastern District of New York
					
	DATED:	 	2/4/09	 		 	BY:	 	/s/ Paul Kaufman
		 		 		 		 	PAUL KAUFMAN
		 		 		 		 	Assistant United States Attorney
		 		 		 		 	Chief, Civil Health Care Fraud
		 		 		 		 	United States Attorney’s Office
		 		 		 		 	Eastern District of New York
					
	DATED:	 	2/4/09	 		 	BY:	 	/s/ Brian McCabe
		 		 		 		 	BRIAN McCABE
		 		 		 		 	Trial Attorney
		 		 		 		 	Commercial Litigation Branch
		 		 		 		 	Civil Division
		 		 		 		 	United States Department of Justice
					
	DATED:	 	2/18/09	 		 	BY:	 	/s/ Gregory E. Demske
		 		 		 		 	GREGORY E. DEMSKE
		 		 		 		 	Assistant Inspector General for Legal Affairs
		 		 		 		 	Office of Counsel to the Inspector General
		 		 		 		 	Office of Inspector General
		 		 		 		 	United States Department of Health and Human Services
					
	DATED:	 	2/10/09	 		 	BY:	 	/s/ Laurel C. Gillespie
		 		 		 		 	LAUREL C. GILLESPIE
		 		 		 		 	Deputy General Counsel
		 		 		 		 	TRICARE Management Activity
		 		 		 		 	United States Department of Defense

  


					
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	DATED:	 	2/3/06	 		 	BY:	 	/s/ Lorraine E. Dettman
		 		 		 		 	LORRAINE E. DETTMAN
		 		 		 		 	Assistant Director for Insurance Service Programs
		 		 		 		 	Center for Retirement and Insurance Services
		 		 		 		 	United States Office of Personnel Management
					
	DATED:	 	2/4/09	 		 	BY:	 	/s/ J. David Cope
		 		 		 		 	J.DAVID COPE
		 		 		 		 	Assistant Inspector General For Legal Affairs
		 		 		 		 	United States Office of Personnel Management

  


					
	 Amendment to Civil Settlement Agreement
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 JPI AND ORPHAN - Defendants 
  

									
					
	DATED:	 	2/6/09	 		 	BY:	 	/s/ Samuel R. Saks
		 		 		 		 	SAMUEL R. SAKS, M.D.
		 		 		 		 	Chief Executive Officer
		 		 		 		 	Jazz Pharmaceuticals, Inc
					
	DATED:	 	2/6/09	 		 	BY:	 	/s/ Bob Myers
		 		 		 		 	ROBERT MYERS.
		 		 		 		 	Member
		 		 		 		 	Orphan Medical, LLC
					
	DATED:	 	2/6/09	 		 	BY:	 	/s/ Mark Jensen
		 		 		 		 	J. SEDWICK SOLLERS III, Esq.
		 		 		 		 	MARK A. JENSEN, Esq.
		 		 		 		 	King & Spalding LLP
		 		 		 		 	Counsel for Jazz Pharmaceuticals Inc. and
		 		 		 		 	Orphan Medical, LLC

  


					
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 RELATOR 
  

									
					
	DATED:	 	2/4/09	 		 	BY:	 	/s/ Shelley Lauterbach
		 		 		 		 	SHELLEY LAUTERBACH
		 		 		 		 	Relator
					
	DATED:	 	2/4/09	 		 	BY:	 	/s/ Larry Zoglin
		 		 		 		 	LARRY ZOGLIN, Esq.
		 		 		 		 	Phillips and Cohen LLP
		 		 		 		 	Counsel for Relator

  


					
	 Amendment to Civil Settlement Agreement
 with Jazz Pharmaceutical, Inc/Orphan Medical
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