### UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D

. C. 20460

OFFICE OF CHEMI C AL S A FETY A ND POLLUTION PREVENT I ON



### M E MORANDUM

Dat e: S eptember 8

, 2015

SU BJE C T : Metho xy fenozid e. Chronic Aggregate D i etary (Foo d and Drinkin g Wat e r )

Ex p osure and Ri sk Assessme n t as Part of th e Met h oxyfe no zide Re g i stratio n R eview and for the Section 

## 3 Re g i s trati o n on C hiv es; Crop G ro up Conve r sio n s for S t one Fruit and Tr ee Nuts.



### P C C od e: 1 2 1027


### D e ci s ion No

. : 49 3332



### P e tition N o

. : 4 E8298 

### DP B a rcod e : 04 26657


### Re g i s tration N o .: 627 19-4 42



### Re g ulatory Action: Sec ti o n 3


### C a se N o. : 7431 

### Ri s k A ss essment Ty p e : D i etary 

### T X R N o .: NA 

### CAS No.: 1 61050

- 58-4
40 

### CF R : § 18 0

. 544 

### MRID N o .: NA

FROM:

THRO UG H:

TO: Elizabeth Holm an, Ph ys ic a l Sc i e ntist**~ ~**  

### Risk Assess m e nt Branch II



### Health Effects Di vis i o n (HED

,**50 9P** **)**

## ~~/L- 

# - Moh se n Sa ha feya n ,**em ·**  

### s .........,... '"'/ .**~** 

### Seyed Ta d ayon , Chem i st
D i etary Ex posur e Scie n ce A visory Council ( DE SAC)

B a rb ara Madde n an d A ndr ew Ertman

, RM Team 5

M in o r Use a nd Eme rg e nc y R es po n se Br anch (MU ERB) Registration D ivis i on 

### ( RD )

, 7505 P

AND

Jill Bl oom, Team Leader
Risk Man age ment and 1 mp l e mentation Branch V
Pesticide R e -eva l uation Di v i s ion



### Exe cuti ve S umm ary

Chronic aggregate di etary [food and dr i nkin g wate r ] exposure and ri sk assess m ents were conducted using th e Dietary Expos ur e Evaluatio n Model software w i th the Fo o d Commodity

P

age I of 18Metho xyfe nozide Dietary Exposure and Ri s k A ss essment DP umb er: 042665 7



### I ntake Database (OEE M-F C ID ) Ver sio n 3. 16. This software u ses 20 03- 2008 food consumption
data from the U.S. D epartment of Agriculture ' s (USDA's) National Health and utrition
Examinat i on Survey

, What We Eat in America

, (NHANES / WWEIA). The analysis was cond ucted in support of a human-he a lth ri sk assessment as part of the methoxyfenozide

r eg istration r ev i e w assessment and for the proposed Section 3 uses of methox y fenozide on chjve

, and crop group conversions for sto n e fruit and tree nut s

. Specifica ll y, crop group co nv ers ion s include the conversion of tree nut group 14 to tree nut group 14-12

, and conversion of stone fruit

g roup 12 except fresh prune plum to sto n e fruit gro up 12-12 except fresh prune plum. This
memorandum was reviewed by two peer reviewers of th e DESAC

, per DESA C SOP 2012

. l.

In calculating dietary risk est imates

, HED has co mp ared the chro ni c population adjusted dos e (c PAD ) to the re s pective estimated dietar y exposures. Typically

, HED has concerns regarding dietary risk when the es timates exceed 100% of the c PAO

. With the conservative assumptions
noted below

, risk estimates associated with di etary e xposu r e to methox y feno z ide are sigruficantly bel ow HED's lev el of concern. No single dose effec t s were noted in the toxicity

s tudie s for methoxyfenozide

, so an acute d iet ary exposure and risk assessment is not relevant. I n addition

, methoxyfenozid e is considered " not likel y" to be carcinogenic

, so cancer risk i s not of

co nc ern.

An 

### unr efi n ed chronic dietary analysis for methoxyf enozide was conducted using tolerance level
residues and 100 % crop

- treated (CT) for a ll existing and proposed uses. Default processing
factors were u sed for most processed commodities that do not have individual tolerances. Drinking water was incorporated directly into the dietary assessment using the maximum

es timated chronic concentration for gro undwat er. The chronic risk estimates from dietary (food

+ drinking water) exposure to methoxyfenozide do not exceed HED ' s le ve l of concern for th e

ge neral U.S. population

, o r any of the population subgroups. The chronic dietary risk est imate
for th e hi g hest exposed population subgroup, child r en 1-2 years old

, is 84 % of the cPAO. The

ge neral U.S. population utilize s 30% of the cPAD.

I. 

### Introduction



### Dietary risk assessment in corporates both exposure and toxicit y of a gi ve n pe s ticide. For acute and chronic assessme nt s , the risk i s expressed as a percentage of a maximum acceptable dose ( i. e

. , the dose th at H E D has concluded wi ll result in no unreasonable adverse health effects).
This dose is referred to as the population-adjusted dose (PAD). The PAD i s eq ui va lent to the point of departure (POD, e.g. no observed adverse effec t l eve l (NOAEL)

, lowest observed
adverse effect level (L OAEL )) divided b y the required uncertainty or safety factors.

For acute and non-cancer chronic exposures , H E D i s concerned when estimated di e tar y risk

ex ceeds 100 % of the PAD. Reference s that discuss the acute and chronic ri sk assessments in

more detail are ava il able on th e E P A/pestic id es web s it e: " Available Information on Assessing

E xpo s ure from Pesticides

, A Use r 's Guide

, " 21-JUN-2000

, web link: http: // www.epa.gov / fedrgstr/EPA

- PEST / 2000 / July / Day-J 2 / 6061.pdf; or see SO P 99.6 ( 20-AUG1 999).

Pa ge 2of18Methoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 3 of 18 

### The most recent dietary risk assessment for methoxyfenozide was con ducted by E. Holman ( 0 4 / 04 /201 4 , D41 3706 ).

II. Residue Information

Tolerances: Permanent tolerances are established for residues of methoxyfenozide in/on a wide variety of plant commodities at levels ranging from 0.05 ppm to 160 ppm [40 CFR §180.544(a)(1)]. Permanent tolerances are also established for residues of methoxyfenozide i n milk, meat, and fat of livestock [40 CFR §180.544(a)(1)], and for the combined residues of parent and its glucuronide conjugate (RH

- 141,518) in eggs and meat byproducts at 0.02

- 0.40 ppm [40 CFR §180.544(a)(2)].

Residue of Concern : T he residue of concern for both the tolerance expression and the risk assessment in primary crops (and drinking water) is methoxyfenozide. The qualitative nature of methoxyfenozide residues in livestock is also adequately understood based on available rumi nant and poultry metabolism studies. HED determined that the residue of concern is parent in milk and ruminant tissues (except meat byproducts), poultry meat and fat. The residues of concern in meat byproducts and eggs are methoxyfenozide and Metabolite RH

- 141,518.

Recommended Tolerances: As part of the current petition ( 4E 8 2 9 8 ), HED recommends ( W.Drew

, DP 425285

, 03/31/2015 ; W. Drew, D429009, 09/08/2015 ) for the tolerance s of methoxyfenozide on chive, as well as crop group conversions for stone fruit and tree nuts, under
40 CFR 180.544 (Table 1)

. In addition, as part of the r egistration review process, in s pring 2013
HED had discussions with Health Canada (PMRA) about harmonizing tolerances for methoxyfenozide. As a result of these discussions, sever al commodities were targeted for possible harmonization. These commodities are currently out of harmonization betwe en USEPA
and Codex and/or P MRA. Therefore , HED is recommending increasing several tolerances solely for the purposes of harmonization, spec ifically those on Bushberry subgroup 13

- 07B; Pea and bean, succulent shelled, subgroup 6B ; and Vegetable, legume, edible podded, subgroup 6A

.

TABLE 1. Tolerance Summary for Methoxyfenozide (40CFR §180.544 ). Propose d or Existing * Commodity Proposed or Existing *

Tolerance (ppm) Recommended

Tolerance (ppm) Correct Commodity Definition ; Comments 40CFR § 180.544[a][1] Fruit, stone, group 12

- 12

, except plum, prune, fresh 3.0 3.0 Conversion from stone fruit group 12 except fresh prune plum

. Nut, tree, group 14

- 12 0.10 0. 1 0 Conversion from tree nut group 14. Herb subgroup 19A, except chive, fresh, leaves 400 400 Herb subgroup 19A, except chive, fresh
leaves . B ased on field trial data on dried chives submitted by IR

- 4. S ubgroup 19A only includes dried chives, not
fresh

. Onion, green, subgroup 3

- 07B, except chive 5.0 5.0 Onion, green, subgroup 3

- 07B, except
chive

, fresh leaves ; Based on field trial data on fresh chives submitted by IR

- 4. Chive, fresh, leaves 30.0 30 Chive , fresh leaves ; b ased on field trial data on fresh chives submitted by IR

- 4.Methoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 4 of 18 TABLE 1. Tolerance Summary for Methoxyfenozide (40CFR §180.544 ). Propose d or Existing * Commodity Proposed or Existing *

Tolerance (ppm) Recommended

Tolerance (ppm) Correct Commodity Definition ; Comments
40CFR § 180.544[a][1] Herb subgroup 19A, except chive * 400* Remove Replace with the tolerance in h erb subgroup 19A , except chive, fresh
leaves

. Onion, green, subgroup 3

- 07B * 5.0* Remove Replace with the tolerance in green

o nion subgroup 3

- 07B except chive

, fresh leaves

. Fruit, stone, group 12, except plum, prune,
fresh * 3 .0 * Remove Conversion to stone fruit group 12

- 12 except fresh prune plum

.

Nut, tree, group 14 * 0. 1 0 * Remove Conversion to tree nut group 14

- 12. Bushberry subgroup 13

- 07B 3.0 * 4.0 Increase tolerance to harmonize with
Codex and PMRA. Pea and bean, succulent shelled, subgroup 6B 0.2 * 0.3 Increase tolerance to harmonize with
Codex and PMRA. Vegetable, legume, edible podded, subgroup 6A 1.5 * 2.0 Increase tolerance to harmonize with
Codex and PMRA.
40CFR § 180.544[ d][2 ]
Chive* 4.5* Remove Covered by new chive tolerance in §180.544[a][1].

* A tolerance is currently established at the listed level in the corresponding commodity.



### Residue Data Used for Chronic Assessment: For this analysis

, existing and recommended
tolerance levels , as well as 100% CT for all commodities were used. DEEM (Version 7.81) default processing factors were used for most processed commodities that do not have individual tolerances; the only exception was a processing factor of 0.2x for orange juice ( D. Rate,
DP 358341, 0 6/10/2009) from a reviewed processing study

. The existing tolerances for livestock
commodities were deemed adequate ( W. Drew

, DP 407758

, 0 7 /16 /2013 ; E. Holman, D413705

, 4/4/2014 ).

T olerances have not been established for residues in fish. HED has determined that “it is appropriate to use the catfish PDP data for a national risk assessment” (ChemSAC minutes, 7/11/2012). The USDA Pesticide Data Program (PDP) monitored pesticide residues in catfish in 2008, 2009, and 2010. Over this 3

- year period, PDP analyzed 1479 samples of catfish for methoxyfenozide residues. None of the samples contained detectable residues. As a result,
residues in fish were not included in the assessment.

I I I. Percent Crop Treated Information

In this chronic assessment, 100% crop treated was assumed for all commodities.

IV. Drinking Water Data

The drinking water residues used in the dietary risk assessment were provided by the Environmental Fate and Effects Division (EFED) in the following memorandum : “ Drinking
Water Assessment for the IR

- 4 New Use Petition for the Use of Methoxyfenozide on Chives, Herb Subgroup 19A, Green Onion Subgroup 3

- 07B and Crop Group Conversions for Stone FruitMethoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 5 of 18 

### Group 12

- 12 (except plum) and Tree Nut Group 14

- 12. ” ( D4 22209

, K. Milians

, 12/09/2014 ) and incorporated directly into this dietary assessment. Water residues were incorporated in the
DEEM

- FCID into the food categories “water, direct, all sources” and “water, indirect, all
sources.”

Drinking water concentrations (EDWCs) were estimated using the FIRST model (FQPA Index Reservoir Screening Tool) for surface water, the SCI

- GROW (Screening Concentration In GROund Water (SCI

- GROW v2.3, Jul. 29, 2003) and PRZM

- GW (Pesticide Root Zone Model for Groundwater, version 1.0, August 31, 2012) models for groundwater. These were the highest EDWCs obtained (of all registered methoxyfenozide uses) and were based on the fruiting vegetable use represented by the WI corn scenario in PRZM

- GW

. Because the new use on chive, as well as the proposed crop group conversions for stone fruit and tree nuts, are proposed at the same maximum application rates than those for previously

- assessed uses, EFED r efers to
the previous assessment for a new use on pineapple ( D416709, I. Negrón

- Encarnación,
12/19/2013 ). T he EDWCs for the pineapple use are lower than the EDWCs from the fruiting vegetable use mainly due to lower application rate of the pineapple use (0.44 lb a.i./A/year) compared to the fruiting vegetable use (1.0 lb a.i./A/year). The EDWC used in this assessment is bolded in the table below, with the value of 214 ppb coming from the groundwater residues estimated by the PRZM

- GW model (Wisconsin corn scenario)

.

Table 2

. Tier I estimated drinking water concentrations (EDWCs) resulting from applications of methoxyfenozide

FIRST
Drinking water source Use (modeled rate) Peak Day Concentration (ppb) Annual Average Concentration (ppb)

Surface water ( aerial application ) Pineapple

(0.11 lb a.i./A x 4 applic.; total of 0.44 lb ai/A/yr) 23.5 7.57

SCI

- GROW
Drinking water source Use (modeled rate) Screening Concentration (ppb)

Groundwater Pineapple

(0.11 lb a.i./A x 4 applic.; total of 0.44 lb ai/A/yr) 1.76

PRZM

- GW

Crop/Scenario Highest Daily value (μg/L) Post Breakthrough

Average (μg/L) Average Simulation

Breakthrough Time (days)

Pineapple/WI corn 108 93.1 8685
Fruiting Vegetable/WI corn 251 214 8684.63



### The drinking water model s and t heir description s are available at the EPA internet site: http://www.epa.gov/oppefed1/models/water/

.

V. DEEM

- FCID Program and Consumption InformationMethoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 6 of 18 

### The m ethoxyfenozide chro nic dietary exposure assessment was conducted using the DEEM

FCID, Version 3.16 , which incorporates 2003

- 2008 consumption data from USDA ’s NHANES/WWEIA. The data are based on the reported consumption of more than 20,000
individuals over two non

- consecutive survey days. Foods “as consumed” (e.g., apple pie) are
linked to EPA

- defined food commodities (e.g.

, apples, peeled fruit

- cooked; f resh or N/S; baked;
or wheat flour

- cooked; fresh or N/S, baked) using publicly available recipe translation files developed jointly by USDA/ARS and EPA. For chronic exposure assessment, consumption data are averaged for the entire U.S. population and wi thin population subgroups . However , for acute exposure assessment

, consumption data are retained as individual consumption events. Based on analysis of the 2003

- 2008 WWEIA consumption data, which took into account dietary patterns and survey respondents, HED concluded that it is most appropriate to report risk for the following population subgroups: the general U.S. population, all infants (<1 year old), children
1

- 2, children 3

- 5, children 6

- 12, youth 13

- 19, adults 20

- 49, females 13

- 49, and adults 50

- 99 years old.

For a chronic dietary exposure assessment, an estimate of the residue level in each food or food

form (e.g., orange or orange juice) on the food commodity residue list is multiplied by the average daily consumption estimate for that food/food form to produce a residue intake estimate. The resulting residue intake estimate for each food/food form is summed with the residue intake estimates for all other food/food forms on the commodity residue list to arrive at the total average estimated expos ure. Exposure is expressed in mg/kg body weight/day and as a percent of the cPAD. This procedure is performed for each population subgroup.

VI. Toxicological Information

The doses and endpoints for dietary exposure and risk assessment are summarized i n Table 3

, below.

Table 3

. Summary of Toxicological Doses and Endpoints for Methoxyfenozide for

Use in Dietary Risk Assessments

Exposure/
Scenario Point of

Departure Uncertainty/

FQPA Safety
Factors RfD, PAD,

Level of
Concern for
Risk
Assessment Study and Toxicological Effects

Acute Dietary (All Populations ) N/A N/A N/A No appropriate single dose endpoint was identified in the oral toxicity studiesMethoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 7 of 18 

### Table 3

. Summary of Toxicological Doses and Endpoints for Methoxyfenozide for

Use in Dietary Risk Assessments

Exposure/
Scenario Point of

Departure Uncertainty/

FQPA Safety
Factors RfD, PAD,

Level of
Concern for
Risk
Assessment Study and Toxicological Effects

Chronic Dietary (All Populations ) NOAEL =

10.2 mg/kg/day UF A 

### =10X

UF H 

### =10X FQPA
SF=1X Chronic RfD

= 0.102 mg/kg/day

cPAD =0. 102 mg/kg/day 2

- Year combined chronic feeding/

carcinogenicity, rats Hematological changes (decreased RBC, hemoglobin and hematocrit), liver toxicity (increased weights, hypertrophy), histopathological changes in thyro id (increased follicular cell hypertrophy, altered colloid), and possible adrenal toxicity (increased weights).
Cancer (oral, dermal, inhalation) Classification: “Not likely to be Carcinogenic to Humans”

Point of Departure (POD) = A data point or an estimated point that is derived from observed dose

- response data and used to mark the beginning of extrapolation to determine risk associated with lower environmentally relevant human exposures. NOAEL = no observed adverse effect level. UF = uncertainty factor. UF A = extrapolation from animal to human (interspecies). UF H = potential variation in sensitivity among members of the human population (intraspecies). FQPA SF = FQPA Safety Factor. PAD = population adjusted dose (a = acute, c = chronic). RfD = reference dose. N/A = not applicable.



### VII. Results/Discussion

As stated above, for acute and chronic assessments, HED is concerned when dietary risk exceeds
100% of the PAD. The DEEM

- FCID analyses estimate the dietary exposure and risk of the U.S

. population and various population subgroups. The results reported in Table 4 are for the general U.S. Population, all infants (<1 year old), children 1

- 2, children 3

- 5, children 6

- 12, youth 13

- 19,
females 13

- 49, adults 20

- 49, and adults 50

- 99 years.

Results of Chronic Dietary Exposure Analysis : Methoxyfenozide chronic dietary (food + drinking water) exposure estimates are below HED ’s level of concern for the U.S. population and each of the population subgroups

. Estimated chronic dietary exposure is 3 0 % of the cPAD for the U.S. population. T he chronic dietary exposure estimate for the highest reported exposed population subg roup, children 1

- 2 years old, is 8 4 % of the cPAD

.

The results of the chronic dietary (food + drinking water) exposure analysis are reported in Table
4. The results of the chronic dietary (food only) exposure analysis are reported in Table 5.Methoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 8 of 18 

### Table 4

. Summary of Dietary ( Food + Drinking Water) Exposure and Risk for

Methoxyfenozide

.

Population Subgroup Acute Dietary
95 th Percentile Chronic Dietary Cancer

Dietary Exposure (mg/kg/day) % aPAD Dietary Exposure (mg/kg/day) % cPAD Dietary Exposure (mg/kg/day) Risk

General U.S. Population

N/A 2 0.030975 30 

### N/A 2 

### N/A
All Infants (<1 year old) 0.046676 4 6



### N/A N/A Children 1

- 2 years old 1 0.085216 8 4

Children 3

- 5 years old 0.064809 6 4

Children 6

- 12 years old 0.035914 35

Youth 13

- 19 years old 0.023505 23

Adults 20

- 49 years old 0.027082 2 7

Adults 50

- 99 years old 0.026924 2 6

Females 13

- 49 years old 0.027696 2 7

1 The subpopulation with the highest risk estimates

. 2 N / A = Not Applicable; no acute dietary endpoint or cancer endpoint was identified for these population subgroups

.



### VIII. Characterization of Inputs/Outputs

This analysis is a highly conservative, unrefined dietary exposure assessment. Further refinement to the analysis could be made through the use of anticipated residues, incorporation of percent crop treated information, and/or monitoring data that better reflect residues at the time of consumption. Since risk estimates are below HED’s level of concern, a more highly refined analysis is not needed at this time. The reported risk estimates are likely to be considerably higher than actual exposure to methoxyfenozide as a result of registered and proposed uses. In
order to provide a comparison for reference, the dietary results for the analysis of f ood exposures (on ly) are presented in attachment 3

.

IX. Conclusions

Based on the conservative assumptions noted above

, chronic dietary risk estimates for methoxyfenozide do not exceed HED ’s level of concern for the general U

. S

. population, or any
of t he population subgroups, including those comprised of infants and children. HED is confident that the assessment does not underestimate risk to the general U.S. populat ion or any population subgroup.

X. List of Attachments

Attachment 1: Chronic Food plus Water Residue Input File
Attachment 2: Chronic Food plus Water Results File
Attachment 3 : Chronic Food Only Results FileMethoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 9 of 18 

### Attachment 1: Chronic Food plus Water Residue Input File

Filename: F: \ methoxyfenozide \ Chive 2014 \ 121027C_040715.R08
Chemical: Methoxyfenozide RfD(Chronic): .102 mg/kg bw/day NOEL(Chronic): 10.2 mg/kg bw/day RfD(Acute): 0 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/day Date created/last modified: 04

- 07

- 2015/18:48:37 Program ver. 3.16, 03

- 08

- d

----------------------------------- ------------------------------------------------ EPA Crop Def Res Adj.Factors Comment Code Grp Commodity Name (ppm) #1 #2

---------- ---- ------------------------------- ---------- ------ ------ ------- 0101050000 1AB Beet, garden, roots 0.900000 1.000 1.000 0101050001 1AB Beet, garden, roots

- babyfood 0.900000 1.000 1.000 0101052000 1A Beet, sugar 0.500000 1.00 0 1.000 0101052001 1A Beet, sugar

- babyfood 0.500000 1.000 1.000 0101053000 1A Beet, sugar, molasses 0.500000 1.000 1.000 0101053001 1A Beet, sugar, molasses

- babyfood 0.500000 1.000 1.000
0101067000 1AB Burdock 0.900000 1.000 1.000
0101078000 1AB Carrot 0.900000 1.000 1.000
0101078001 1AB Carrot

- babyfood 0.900000 1.000 1.000 0101079000 1AB Carrot, juice 0.900000 1.000 1.000
0101084000 1AB Celeriac 0.900000 1.000 1.000 0101100000 1AB Chicory, roots 0.900000 1.000 1.000 0101168000 1AB Ginseng, dried 0.900000 1. 000 1.000
0101190000 1AB Horseradish 0.900000 1.000 1.000 0101250000 1AB Parsley, turnip rooted 0.900000 1.000 1.000 0101251000 1AB Parsnip 0.900000 1.000 1.000
0101251001 1 AB Parsnip

- babyfood 0.900000 1.000 1.000 0101314000 1AB Radish, roots 0.900000 1.000 1.000 0101316000 1AB Radish, Oriental, roots 0.900000 1.000 1.000 0101327000 1AB Rutabaga 0.900000 1.000 1.000 0101331000 1AB Salsify, roots 0.900000 1.000 1.000 0101388000 1AB Turnip, roots 0.900000 1.000 1.000
0103015000 1CD Arrowroot , flour 0.020000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0103015001 1CD Arrowroot, flour

- babyfood 0.020000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0103017000 1CD Artichoke, Jerusalem 0.020000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0103082000 1CD Cassava 0.020000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259

0103082001 1CD Cassava

- babyfood 0.020000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0103139000 1CD Dasheen, corm 0.020000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0103166000 1CD Ginger 0.020000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259

010316 6001 1CD Ginger

- babyfood 0.020000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0103167000 1CD Ginger, dried 0.020000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0103296000 1C Potato, chips 0.020000 1.000 1.000 0103297000 1C Potato, dry (granules/ flakes) 0.020000 6.500 1.000 0103297001 1C Potato, dry (granules/ flakes)

- b 0.020000 6.50 0 1.000 0103298000 1C Potato, flour 0.020000 6.500 1.000 0103298001 1C Potato, flour

- babyfood 0.020000 6.500 1.000 0103299000 1C Potato, tuber, w/peel 0.020000 1.000 1.000

0103299001 1C Potato, tuber, w/peel

- babyfood 0.020000 1.000 1.000 0103300000 1C Potato, tuber, w/o peel 0.020000 1.000 1.000 0103300001 1C Potato, tuber, w/o peel

- babyfood 0.020000 1.000 1.000 0103366000 1CD Sweet potato 0.020000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0103366001 1CD Sweet potato

- babyfood 0.020000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F062 59 0103371000 1CD Tanier, corm 0.020000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0103387000 1CD Turmeric 0.020000 1.000 1.000 PP#: 9Methoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 10 of 18 Full comm ent: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0103406000 1CD Yam, true 0.020000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259

0103407000 1CD Yam bean 0.020000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0200051000 2 Beet, garden, tops 30.000000 1.000 1.000 0200101000 2 Chicory, tops 30.000000 1.000 1.000
0200140000 2 Dasheen, leaves 30.000000 1.000 1.000 0200315000 2 Radish, tops 30.000000 1.000 1.000 0200317000 2 Radish, Oriental, tops 30.000000 1.000 1.000 0200332000 2 Salsify, tops 30.000000 1.000 1.000 0301165000 3A Garlic, bulb 0.100000 1.000 1.000 0301165001 3A Garlic, bulb

- babyfood 0.100000 1.000 1.000 0301237000 3A Onion, bulb 0.100000 1.0 00 1.000 0301237001 3A Onion, bulb

- babyfood 0.100000 1.000 1.000 0301238000 3A Onion, bulb, dried 0.100000 9.000 1.000 0301238001 3A Onion, bulb, dried

- babyfood 0.100000 9.000 1.000
0301338000 3A Shallot, bulb 0.100000 1.000 1.000 0302103000 3B Chive, fresh leaves 30.000000 1.000 1.000
0302198000 3B Leek 5.000000 1.000 1.000 0302239000 3B Onion, green 5.000000 1.000 1.000 0302338500 3B Shallot, fresh leaves 5.000000 1.000 1.000 0401005000 4A Amaranth, leafy 30.000000 1.000 1.000 PP#: 9

Full co mment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0401018000 4A Arugula 30.000000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0401104000 4A Chrysanthemum, garland 30.000000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0401133000 4A Cress, garden 30.000000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259

0401134000 4A Cr ess, upland 30.000000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0401138000 4A Dandelion, leaves 30.000000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F 06201, 0F06213, 1F06259 0401150000 4A Endive 30.000000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0401204000 4A Lettuce, head 30.000000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0401205000 4A Lettuce, leaf 30.000000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0401248000 4A Parsley, leaves 30.000000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0401313000 4A Radicchio 30.000000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0401355000 4A Spinach 30.000000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 0401355001 4A Spinach

- babyfood 30.000000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259

0402076000 4B Cardoon 25.000000 1.000 1.000 0402085000 4B Celery 25.000000 1.000 1.000 0402085001 4B Celery

- babyfood 25.000000 1.000 1.000 0402086000 4B Celery, juice 25.000000 1.000 1.000
0402087000 4B Celtuce 25.000000 1.000 1.000 0402152000 4B Fennel, Florence 25.000000 1.000 1.000
0402322000 4B Rhubarb 25.000000 1.000 1.000
0402367000 4B Swiss chard 25.000000 1.000 1.000
0501061000 5A Broccoli 7.000000 1.000 1.000
050106100 1 5A Broccoli

- babyfood 7.000000 1.000 1.000 0501062000 5A Broccoli, Chinese 7.000000 1.000 1.000 0501064000 5A Brussels sprouts 7.000000 1.000 1.000 0501069000 5A Cabbage 7.000000 1.000 1.000 0501071000 5A Cabbage, Chinese, napa 7.000000 1.000 1.000 0501072000 5A Cabbage, Chinese, mustard 7.000000 1.000 1.000
0501083000 5A Cauliflower 7.000000 1.000 1.000
0501196000 5A Kohlrabi 7.000000 1.000 1.000
0502063000 5B Broccoli raab 30.000000 1.000 1.000 0502070000 5B Cabbage, Chinese, bok choy 30.000000 1.000 1.000Methoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 11 of 18 0502117 000 5B Collards 30.000000 1.000 1.000
0502194000 5B Kale 30.000000 1.000 1.000 0502229000 5B Mustard greens 30.000000 1.000 1.000 0502318000 5B Rape greens 30.000000 1.000 1.000 0502389000 5B Turnip, greens 30.000000 1.000 1.000 0600347000 6 Soybean, seed 1.000000 1.000 1.000 0600349000 6 Soybean, soy milk 1.0000 00 1.000 1.000 0600349001 6 Soybean, soy milk

- babyfood or in 1.000000 1.000 1.000 0600350000 6 Soybean, oil 1.000000 1.000 1.000 0600350001 6 Soybean, oil

- babyfood 1.000000 1.000 1.000 0601043000 6A Bean, snap, succulent 2.000000 1.000 1.000 0601043001 6A Bean, snap, succulent

- babyfood 2.000000 1.000 1.000 0601257000 6A Pea, edible podded, succulent 2.000000 1.000 1.000 0602031000 6B Bean, bro ad, succulent 0.300000 1.000 1.000 0602033000 6B Bean, cowpea, succulent 4.000000 1.000 1.000 0602037000 6B Bean, lima, succulent 0.300000 1.000 1.000 0602255000 6B Pea, succulent 0.300000 1.000 1.000 0602255001 6B Pea, succulent

- babyfood 0.300000 1.000 1.000 0602259000 6B Pea, pigeon, succulent 0.300000 1.000 1.000 0603030000 6C Bean, black, seed 0.500000 1.000 1.000 0603032000 6C Bean, broad, seed 0.500000 1.000 1.000 0603034000 6C Bean, cowpea, seed 4.000000 1.000 1.000 0603035000 6C Bean, great northern, seed 0.500000 1.000 1.000 0603036000 6C Bean, k idney, seed 0.500000 1.000 1.000 0603038000 6C Bean, lima, seed 0.500000 1.000 1.000 0603039000 6C Bean, mung, seed 0.500000 1.000 1.000 0603040000 6C Bean, navy, seed 0.500000 1.000 1.000 0603041000 6C Bean, pink, seed 0.500000 1.000 1.000 0603042000 6C Bean, pinto, seed 0.500000 1.000 1.000 0603098000 6C Chickpea, seed 0.500000 1.000 1.00 0 0603098001 6C Chickpea, seed

- babyfood 0.500000 1.000 1.000 0603099000 6C Chickpea, flour 0.500000 1.000 1.000 0603182000 6C Guar, seed 0.500000 1.000 1.000 0603182001 6C Guar, seed

- babyfood 0.500000 1.000 1.000 0603203000 6C Lentil, seed 0.500000 1.000 1.000 0603256000 6C Pea, dry 0.500000 1.000 1.000 0603256001 6C Pea, dry

- babyfood 0.500000 1.000 1.000 0603258000 6C Pea, pigeon, seed 0.500000 1.000 1.000 0603348000 6C Soybean, flour 1.000000 1.000 1.000 0603348001 6C Soybean, flour

- babyfood 1.000000 1.000 1.000
0801374000 8A Tomatillo 2.000000 1.000 1.000
0801375000 8A Tomato 2.000000 1.000 1.000
0801375001 8A Tomato

- babyfood 2.000000 1.000 1.000 0801376000 8A Tomato, paste 2.000000 5.400 1.000 0801376001 8A Tomato, paste

- babyfood 2.000000 5.400 1.000 0801377000 8A Tomato, puree 2.000000 3.300 1.000 0801377001 8A Tomato, puree

- babyfood 2.000000 3.300 1.000 0801378000 8A Tomato, dried 2.000000 14.300 1.000 0801378001 8A Tomato, dried

- babyfood 2.000000 14.300 1.000 0801379000 8A Tomato, juice 2.000000 1.500 1.000 0801380000 8A Tomato, Tree 2.000000 1.000 1.000 0802148000 8BC Eggplant 2.000000 1.000 1.000
0802234000 8BC Okra 2.000000 1.000 1.000 0802270000 8B Pepper, bell 2.000000 1.000 1.000 0802270001 8B Pepper, bell

- babyfood 2.000000 1.000 1.000 0802271000 8B Pepper, bell, dried 2.000000 1.000 1.00 0 0802271001 8B Pepper, bell, dried

- babyfood 2.000000 1.000 1.000 0802272000 8BC Pepper, nonbell 2.000000 1.000 1.000 0802272001 8BC Pepper, nonbell

- babyfood 2.000000 1.000 1.000 0802273000 8BC Peppe r, nonbell, dried 2.000000 1.000 1.000 0901075000 9A Cantaloupe 0.300000 1.000 1.000 0901187000 9A Honeydew melon 0.300000 1.000 1.000
0901399000 9A Watermelon 0.300000 1.000 1.000 0901400000 9A Watermelon, juice 0.300000 1.000 1.000 0902021000 9B Balsam pear 0.300000 1.000 1.000 0902088000 9B Chayote, fruit 0.300000 1.000 1.000 0902102000 9B Chinese waxgourd 0.300000 1.000 1.000Methoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 12 of 18 0902135000 9B Cucumber 0.300000 1.000 1.000 0902308000 9B Pumpkin 0.300000 1.000 1.000 0902309000 9B Pumpkin, seed 0.300000 1.000 1.000 0902356000 9B Squash, summer 0.300000 1.000 1.000 0902356001 9B Squash, summer

- babyfood 0.300000 1.000 1.000 0902357000 9B Squash, winter 0.300000 1.000 1.000 0902357001 9B Squash, winter

- babyfood 0.300000 1.000 1.000
1001106000 10A Citron 3.000000 1.000 1.000 PP# 1E

Full comment: PP# 1E7842 1001107000 10A Citrus hybrids 3.000000 1.000 1.000 PP# 1E

Full comment: PP# 1E7842 1001108000 10A Citrus, oil 100.000000 1.000 1.000 PP# 1E

Full comment: PP# 1E7842 1001240000 10A Orange 3.000000 1.000 1.000 PP# 1E

Full comment: PP# 1E7842 1001241000 10A Orange, juice 3.000000 0.200 1.000 PP# 1E

Full comment : PP# 1E7842 1001241001 10A Orange, juice

- babyfood 3.000000 0.200 1.000 PP# 1E

Full comment: PP# 1E7842 1001242000 10A Orange, peel 3.000000 1.000 1.000 PP# 1E

Full comment: PP# 1E7842

100 1369000 10A Tangerine 3.000000 1.000 1.000 PP# 1E

Full comment: PP# 1E7842 1001370000 10A Tangerine, juice 3.000000 2.300 1.000 PP# 1E

Full comment: PP# 1E7842

1002197000 10B Kumquat 3.000000 1.000 1.000 PP# 1E

Full comment: PP# 1E7842 1002199000 10B Lemon 3.000000 1.000 1.000 PP# 1E

Full comment: PP# 1E7842 1002200000 10B Lemon, juice 3.000000 2.000 1.000 PP# 1E

Full comment: PP# 1E7842 1002200001 10B Lemon, juice

- babyfood 3.000000 2.000 1.000 PP# 1E

Full comment: PP# 1E7842 1002201000 10B Lemon, peel 3.000000 1.000 1.000 PP# 1E

Full comment: PP# 1E7842 1002206000 10B Lime 3.000000 1.000 1.000 PP# 1E

Full comment: PP# 1E7842 1002207000 10B Lime, juice 3.000000 2. 000 1.000 PP# 1E

Full comment: PP# 1E7842 1002207001 10B Lime, juice

- babyfood 3.000000 2.000 1.000 PP# 1E

Full comment: PP# 1E7842 1003180000 10C Grapefruit 3.000000 1.000 1.000 PP# 1E

Full comment: PP# 1E7842 1003181000 10C Grapefruit, juice 3.000000 2.100 1.000 PP# 1E

Full comment: PP# 1E7842 1003307000 10C Pummelo 3.000000 1.000 1.000 PP# 1E

F ull comment: PP# 1E7842 1100007000 11 Apple, fruit with peel 2.000000 1.000 1.000 1100008000 11 Apple, peeled fruit 2.000000 1.000 1.000 1100008001 11 Apple, peeled fruit

- babyfood 2.000000 1.000 1.000

1 100009000 11 Apple, dried 2.000000 8.000 1.000 1100009001 11 Apple, dried

- babyfood 2.000000 8.000 1.000 1100010000 11 Apple, juice 2.000000 1.300 1.000 1100010001 11 Apple, juice

- babyfood 2.000000 1.300 1.000 1100011000 11 Apple, sauce 2.000000 1.000 1.000 1100011001 11 Apple, sauce

- babyfood 2.000000 1.000 1.000 1100129000 11 Crabapple 2.000000 1.000 1.000 1100173500 11 Goji berry 2.000000 1.000 1.000 Goji i

Full comment: Goji is in Crop Group 8

- 10 1100210000 11 Loquat 2.000000 1.000 1.000
1100266000 11 Pear 2.000000 1.000 1.000
1100266001 11 Pear

- babyfood 2.000000 1.000 1.000 1100267000 11 Pear, dried 2.000000 6.250 1.000
1100268000 11 Pear, juice 2.000000 1.000 1.000 1100268001 11 Pear, juice

- babyfood 2.000000 1.000 1.000 1100310000 11 Quince 2.000000 1.000 1.000 1201090000 12A Cherry 3.000000 1.000 1.000Methoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 13 of 18 1201090001 12A Cherry

- babyfood 3.000000 1.000 1.000 1201091000 12A Cherry, juice 3.000000 1.500 1.000 1201091001 12A Cherry, juice

- babyfood 3.000000 1.50 0 1.000 1202012000 12B Apricot 3.000000 1.000 1.000 1202012001 12B Apricot

- babyfood 3.000000 1.000 1.000 1202013000 12B Apricot, dried 3.000000 6.000 1.000
1202014000 12B Apricot, juice 3.000000 1.000 1.000 1202014001 12B Apricot, juice

- babyfood 3.000000 1.000 1.000
1202230000 12B Nectarine 3.000000 1.000 1.000
1202260000 12B Peach 3.000000 1.000 1.000
1202260001 12B Peach

- babyfood 3.000000 1.000 1.000 1202261000 12B Peach, dried 3.000000 7.000 1.000 1202261001 12B Peach, dried

- babyfood 3.000000 7. 000 1.000 1202262000 12B Peach, juice 3.000000 1.000 1.000 1202262001 12B Peach, juice

- babyfood 3.000000 1.000 1.000
1203285000 12C Plum 3.000000 1.000 1.000
1203285001 12C Plum

- babyfood 3.000000 1.000 1.000 1203286000 12C Plum, prune, fresh 0.300000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 1203286001 12C Plum, prune, f resh

- babyfood 0.300000 1.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 1203287000 12C Plum, prune, dried 0.300000 5.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F062 13, 1F06259 1203287001 12C Plum, prune, dried

- babyfood 0.300000 5.000 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 1203288000 12C Plum, prune, juice 0.300000 1.400 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 1203288001 12C Plum, prune, juice

- babyfood 0.300000 1.400 1.000 PP#: 9

Full comment: PP#: 9F06062, 0F06201, 0F06213, 1F06259 1301055000 13A Blackberry 6. 000000 1.000 1.000 1301056000 13A Blackberry, juice 6.000000 1.000 1.000 1301056001 13A Blackberry, juice

- babyfood 6.000000 1.000 1.000 1301058000 13A Boysenberry 6.000000 1.000 1.000

1 301208000 13A Loganberry 6.000000 1.000 1.000 1301320000 13A Raspberry 6.000000 1.000 1.000 1301320001 13A Raspberry

- babyfood 6.000000 1.000 1.000 1301321000 13A Raspberry, juice 6.000000 1.000 1.000 1301321001 13A Raspberry, juice

- babyfood 6.000000 1.000 1.000 1302057000 13B Blueberry 4.000000 1.000 1.000 1302057001 13B Blueberry

- babyfood 4.000000 1.000 1.000
1302136000 13B Currant 4.000000 1.000 1.000 1302137000 13B Currant, dried 4.000000 1.000 1.000 1302149000 13B Elderberry 4.000000 1.000 1.000 1302174000 13B Gooseberry 4.000000 1.000 1.000 1302191000 13B Huckleberry 4.000000 1.000 1.000 1304175000 13D Grape 1.000000 1.000 1.000 1304176000 13D Grape, j uice 1.000000 1.200 1.000 1304176001 13D Grape, juice

- babyfood 1.000000 1.200 1.000 1304179000 13D Grape, wine and sherry 1.000000 1.000 1.000 1307130000 13G Cranberry 0.500000 1.000 1.000 1307130001 13G Cranberry

- babyfood 0.500000 1.000 1.000 1307131000 13G Cranberry, dried 0.500000 1.000 1.000 1307132000 13G Cranberry, juice 0.500000 1.100 1.000 1307132001 13G Cranberry, juice

- babyfood 0.500000 1.100 1.000 1307359000 13G Strawberry 2.000000 1.000 1.000 1307359001 13G Strawberry

- babyfood 2.000000 1.000 1.000
1307360000 13G Strawb erry, juice 2.000000 1.000 1.000 1307360001 13G Strawberry, juice

- babyfood 2.000000 1.000 1.000
1400003000 14 Almond 0.100000 1.000 1.000
1400003001 14 Almond

- babyfood 0.100000 1.000 1.000 1400004000 14 Almond, oil 0.100000 1.000 1.000 1400004001 14 Almond, oil

- babyfood 0.100000 1.000 1.000
1400059000 14 Brazil nut 0.100000 1.000 1.0 00
1400068000 14 Butternut 0.100000 1.000 1.000
1400081000 14 Cashew 0.100000 1.000 1.000
1400092000 14 Chestnut 0.100000 1.000 1.000
1400155000 14 Haze lnut 0.100000 1.000 1.000Methoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 14 of 18 1400156000 14 Hazelnut, oil 0.100000 1.000 1.000 1400185000 14 Hickory nut 0.100000 1.000 1.000
1400213000 14 Macadamia nut 0.100000 1.000 1.000
1400269000 14 Pecan 0.100000 1.000 1.000
1400278000 14 Pine nut 0.100000 1.000 1.000
1400282000 14 Pistachio 0.100000 1.000 1.000
1400391000 14 Walnut 0.100000 1.000 1.000 1500122000 15 Corn, field, bran 0.050000 1.000 1.000 1500123000 15 Corn, fie ld, starch 0.050000 1.000 1.000 1500123001 15 Corn, field, starch

- babyfood 0.050000 1.000 1.000 1500124000 15 Corn, field, syrup 0.050000 1.500 1.000 1500124001 15 Corn, field, syrup

- babyfood 0.050000 1.500 1.000 1500125000 15 Corn, field, oil 0.200000 1.000 1.000 1500125001 15 Corn, field, oil

- babyfood 0.200000 1.000 1.000 1500126000 15 Corn, pop 0.050000 1.000 1.000 PP# 8E

Full comment: PP# 8E7447 1500127000 15 Corn, sweet 0.050000 1.000 1.000 1500127001 15 Corn, sweet

- babyfood 0.050000 1.000 1.000 1500344000 15 Sorghum, grain 6.0000 00 1.000 1.000 1500345000 15 Sorghum, syrup 6.000000 1.000 1.000 1901028000 19A Basil, fresh leaves 400.000000 1.000 1.000 1901028001 19A Basil, fresh leaves

- babyfood 400.000000 1.000 1.000
19010 29000 19A Basil, dried leaves 400.000000 1.000 1.000 1901029001 19A Basil, dried leaves

- babyfood 400.000000 1.000 1.000 1901102500 19A Chive, dried leaves 400.000000 1.000 1.000 1901118000 19A Cilantro, leav es 400.000000 1.000 1.000 1901118001 19A Cilantro, leaves

- babyfood 400.000000 1.000 1.000
1901144000 19A Dillweed 400.000000 1.000 1.000 1901184000 19A Herbs, other 400.00 0000 1.000 1.000 1901184001 19A Herbs, other

- babyfood 400.000000 1.000 1.000 1901202000 19A Lemongrass 400.000000 1.000 1.000 1901220000 19A Marjoram 400.000000 1.000 1.000 1901220001 19A Marjoram

- babyfood 400.000000 1.000 1.000 1901249000 19A Parsley, dried leaves 400.000000 1.000 1.000 1901249001 19A Parsley, dried leaves

- babyfood 400.000000 1.000 1.000 1901334000 19A Savory 400.000000 1.000 1.000
1902105000 19B Cinnamon 4.500000 1.000 1.000
1902105001 19B Cinnamon

- babyfood 4.500000 1.000 1.000 1902119000 19B Coriander, seed 4.500000 1.000 1.000 1902119001 19B Coriander, seed

- babyfood 4.500000 1.000 1.000 1902143000 19B Dill, seed 4.500000 1.000 1.000 1902274000 19B Pepper, black and white 4.500000 1.000 1.000 1902274001 19B Pepper, black and white

- babyfood 4.500000 1.000 1.000 1902354000 19B Spices, other 4.500000 1.000 1.000 1902354001 19B Spices, other

- babyfood 4.500000 1.000 1.000
2001163000 20A Flax se ed, oil 1.000000 1.000 1.000 2001319000 20A Rapeseed, oil 1.000000 1.000 1.000 2001319001 20A Rapeseed, oil

- babyfood 1.000000 1.000 1.000 2001336000 20A Sesame, seed 1.000000 1.000 1.000 2001336001 20A Sesame, seed

- babyfood 1.000000 1.000 1.000 2001337000 20A Sesame, oil 1.000000 1.000 1.000 2001337001 20A Sesame, oil

- babyfood 1.000000 1.000 1.00 0 2002330000 20B Safflower, oil 1.000000 1.000 1.000 2002330001 20B Safflower, oil

- babyfood 1.000000 1.000 1.000 2002364000 20B Sunflower, seed 1.000000 1.000 1.000
2002365000 20B Sunfl ower, oil 1.000000 1.000 1.000 2002365001 20B Sunflower, oil

- babyfood 1.000000 1.000 1.000 2003128000 20C Cottonseed, oil 2.000000 1.000 1.000 2003128001 20C Cottonseed, oil

- babyfood 2.000000 1.000 1.000 3100044000 31 Beef, meat 0.020000 1.000 1.000 3100044001 31 Beef, meat

- babyfood 0.020000 1.000 1.000 3100045000 31 Beef, meat, dried 0.020000 1.920 1.000 3100046000 31 Beef, meat byproducts 0.100000 1.000 1.000 3100046001 31 Beef, meat byproducts

- babyfood 0.100000 1.000 1.000 3100047000 31 Beef, fat 0.500000 1.000 1.000 3100047001 31 Beef, fat

- babyfood 0.500000 1.000 1.000 3100048000 31 Beef, kidney 0.100000 1.000 1.000Methoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 15 of 18 3100049000 31 Beef, liver 0.400000 1.000 1.000 3100049001 31 Beef, liver

- babyfood 0.400000 1.000 1.000 3200169000 32 Goat, meat 0.020000 1.000 1.000 3200170000 32 Goat, meat byproducts 0.100000 1.000 1.000 3200171000 32 Goat, fat 0.500000 1.000 1.000 3200172000 32 Goat, kidney 0.100000 1.000 1.000 3200173000 32 Goat, liver 0.400000 1.000 1.000 3300189000 33 Horse, meat 0.020000 1.000 1.000 3400290000 34 Pork, meat 0.020000 1.000 1.000 3400290001 34 Pork, meat

- babyfood 0.020000 1.000 1.000 3400291000 34 Pork, skin 0.020000 1.000 1.000 3400292000 34 Pork, meat byproducts 0.020000 1.000 1.000 3400292001 34 Pork, meat byproducts

- babyfood 0.020000 1.000 1.000 3400293000 34 Pork, fat 0.100000 1.000 1.00 0 3400293001 34 Pork, fat

- babyfood 0.100000 1.000 1.000 3400294000 34 Pork, kidney 0.020000 1.000 1.000 3400295000 34 Pork, liver 0.100000 1.000 1.000 3500339000 35 Sheep , meat 0.020000 1.000 1.000 3500339001 35 Sheep, meat

- babyfood 0.020000 1.000 1.000 3500340000 35 Sheep, meat byproducts 0.100000 1.000 1.000 3500341000 35 Sheep, fat 0.500000 1.000 1.000 3500341001 35 Sheep, fat

- babyfood 0.500000 1.000 1.000 3500342000 35 Sheep, kidney 0.100000 1.000 1.000 3500343000 35 Sheep, li ver 0.400000 1.000 1.000 3600222000 36 Milk, fat 0.100000 1.000 1.000 3600222001 36 Milk, fat

- baby food/infant formu 0.100000 1.000 1.000 3600223000 36 Milk, nonfat solids 0.100000 1.000 1.000 3600223001 36 Milk, nonfat solids

- baby food/in 0.100000 1.000 1.000 3600224000 36 Milk, water 0.100000 1.000 1.000 3600224001 36 Milk, water

- babyfood/infant form 0.100000 1.000 1.000 3600225001 36 Milk, sugar (lactose)

- baby food/ 0.100000 1.000 1.000 4000093000 40 Chicken, meat 0.020000 1.000 1.000 4000093001 40 Chicken, meat

- babyfood 0.020000 1.000 1.000
4000094000 40 Chicken , liver 0.100000 1.000 1.000 4000095000 40 Chicken, meat byproducts 0.020000 1.000 1.000 4000095001 40 Chicken, meat byproducts

- babyfoo 0.020000 1.000 1.000 4000096000 40 Chicken, fat 0.020000 1.000 1.000 4000096001 40 Chicken, fat

- babyfood 0.020000 1.000 1.000 4000097000 40 Chicken, skin 0.020000 1.000 1.000 4000097001 40 Chicken, skin

- babyfood 0.020000 1.000 1.00 0 5000382000 50 Turkey, meat 0.020000 1.000 1.000 5000382001 50 Turkey, meat

- babyfood 0.020000 1.000 1.000 5000383000 50 Turkey, liver 0.100000 1.000 1.000
5000383001 50 Turke y, liver

- babyfood 0.100000 1.000 1.000 5000384000 50 Turkey, meat byproducts 0.020000 1.000 1.000 5000384001 50 Turkey, meat byproducts

- babyfood 0.020000 1.000 1.000 5000385000 50 Turkey, fat 0.020000 1.000 1.000 5000385001 50 Turkey, fat

- babyfood 0.020000 1.000 1.000 5000386000 50 Turkey, skin 0.020000 1.000 1.000 5000386001 50 Turkey, skin

- babyfood 0.020000 1.000 1.000 6000301000 60 Poultry, other, meat 0.020000 1.000 1.000 6000302000 60 Poultry, other, liver 0.100000 1.000 1.000 6000303000 60 Poultry, other, meat byproducts 0.020000 1.000 1.000 6000304000 60 Poultry, other, fat 0.020000 1.000 1.000 6000305000 60 Poultry, other, skin 0.020000 1.000 1.000 7000145000 70 Egg, whole 0.020000 1.000 1.000 7000145001 70 Egg, whole

- babyfood 0.020000 1.000 1.000 7000146000 70 Egg, white 0.020000 1.000 1.000 7000146001 70 Egg, white (solids)

- babyfood 0.020000 1.000 1.000 7000147000 70 Egg, yolk 0.020000 1.000 1.000 7000147001 70 Egg, yolk

- babyfood 0.020000 1.000 1.000 8601000000 86A Water, direct, all sources 0.214000 1.000 1.000 8602000000 86B Water, indirect, all sources 0.214000 1.000 1.000
9500001000 O Acerola 0.400000 1.000 1.000 9500016000 O Artichoke, globe 3.000000 1.000 1.000 9500019500 O Atemoya 0.600000 1.000 1.000
9500020000 O Avocado 0.600000 1.000 1.000Methoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 16 of 18 9500074000 O Canistel 0.600000 1.000 1.000 9500089000 O Cherimoya 0.600000 1.000 1.00 0
9500141000 O Date 8.000000 1.000 1.000 9500151000 O Feijoa 0.400000 1.000 1.000 9500177000 O Grape, leaves 1.000000 1.000 1.000 9500178000 O Grape , raisin 1.500000 1.000 1.000
9500183000 O Guava 0.400000 1.000 1.000
9500183001 O Guava

- babyfood 0.400000 1.000 1.000 9500209000 O Longan 2.000000 1.000 1.000 9500211000 O Lychee 2.000000 1.000 1.000 9500212000 O Lychee, dried 2.000000 1.850 1.000 9500215000 O Mango 0.600000 1.000 1.000 9500215001 O Mango

- babyfood 0.600000 1.000 1.000 9500216000 O Mango, dried 0.600000 1.000 1.000 9500217000 O Mango, ju ice 0.600000 1.000 1.000 9500217001 O Mango, juice

- babyfood 0.600000 1.000 1.000 9500245000 O Papaya 0.600000 1.000 1.000 9500245001 O Papaya

- babyfood 0.600000 1.000 1.000 9500246000 O Papaya, dried 0.600000 1.800 1.000 9500247000 O Papaya, juice 0.600000 1.500 1.000
9500252000 O Passionfruit 0.400000 1.000 1.000
9500252001 O Passionfruit

- babyfood 0.400000 1.000 1.000 9500253000 O Passionfruit, juice 0.400000 1.000 1.000 9500253001 O Passionfruit, juice

- babyfood 0.400000 1.000 1.000
9500263000 O Peanut 0.020000 1.000 1.000 9500264000 O Peanut, butter 0.020000 1.890 1.000 9500265000 O Peanut, oil 0.040000 1.000 1.000 9500275000 O Peppermint 7.000000 1.000 1.000 9500276000 O Peppermint, oil 7.000000 1.000 1.000 9500279000 O Pineapple 0.700000 1.000 1.000 9500279001 O Pineapple

- babyfood 0.700000 1.000 1.00 0 9500280000 O Pineapple, dried 0.700000 5.000 1.000 9500281000 O Pineapple, juice 0.700000 1.700 1.000 9500281001 O Pineapple, juice

- babyfood 0.700000 1.700 1.000 9500289000 O Pomeg ranate 0.600000 1.000 1.000 PP# 8E

Full comment: PP# 8E7447 9500333000 O Sapote, Mamey 0.600000 1.000 1.000 9500346000 O Soursop 0.600000 1.000 1.000 9500351000 O Spanish lime 2.000000 1.000 1.000 9500352000 O Spearmint 7.000000 1.000 1.000 9500353000 O Spearmint, oil 7.000000 1.000 1.000
9500358000 O Starfruit 0.400000 1.000 1.000Methoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 17 of 18 

### Attachment 2: Chronic (Food + Drinking Water) Results File

US EPA Ver. 3.16, 03

- 08

- d

DEEM

- FCID Chronic analysis for METHOXYFENOZIDE NHANES 2003

- 2008 2

- day
Residue file name: F: \ methoxyfenozide \ Chive 2014 \ 121027C_040715.R08 Adjustment factor #2 NOT used. Analysis Date 04

- 07

- 2015/18:50:53 Residue file dated: 04

- 07

- 2015/18:48:37

R eference dose (RfD, Chronic) = .102 mg/kg bw/day

=============================================================================== Total exposure by population subgroup

-------------------------------------------------------------------------------

Total Exposure

----------------------------------- Population mg/kg Percent of Subgroup body wt/day Rfd

-------------------------------------- ------------- ---------------- Total US Population 0.030975 30.4% Hispanic 0.032394 31.8%

Non

- Hisp

- White 0.030775 30.2%

Non

- Hisp

- Black 0.028997 28.4%

Non

- Hisp

- Other 0.034710 34.0% Nursing Infants 0.025010 24.5%

Non

- Nursing Infants 0.056354 55.2%
Female 13+ PREG 0.029 225 28.7%
Children 1

- 6 0.069838 68.5%
Children 7

- 12 0.033179 32.5%
Male 13

- 19 0.022977 22.5%
Female 13

- 19/NP 0.024009 23.5%

Male 20+ 0.025122 24.6% Female 20+/NP 0.028666 28.1%

Seniors 55+ 0.026614 26.1%
All Infants 0.046676 45.8%
Female 13

- 50 0.027684 27.1%
Children 1

- 2 0.085216 83.5%
Chi ldren 3

- 5 0.064809 63.5%
Children 6

- 12 0.035914 35.2%
Youth 13

- 19 0.023505 23.0%
Adults 20

- 49 0.027082 26.6%
Adults 50

- 99 0.026924 26.4%
Female 13

- 49 0.027696 27.2%

---------------------------------------------------------------------- ---------Methoxyfenozide Dietary Exposure and Risk Assessment DP Number: D426657

Page 18 of 18 

### Attachment 3 : Chronic (Food Only) Results File

US EPA Ver. 3.16, 03

- 08

- d

DEEM

- FCID Chronic analysis for METHOXYFENOZIDE NHANES 2003

- 2008 2

- day
Residue file name: F: \ methoxyfenozide \ Chive 2014 \ 121027C_040715 food only.R08 Adjustment factor #2 NOT used. Analysis Date 04

- 07

- 2015/18:52:16 Residue file dated: 04

- 07

- 2015/18:50:14 Reference dose (RfD, Chronic) = .102 mg /kg bw/day

=============================================================================== Total exposure by population subgroup

-------------------------------------------------------------------------------

Total Exposure

----------------------------------- Population mg/kg Percent of Subgroup body wt/day Rfd

-------------------------------------- ------------- ---------------- Total US Population 0.026494 26.0% Hispanic 0.028115 27.6%

Non

- Hisp

- White 0.026166 25.7%

Non

- Hisp

- Black 0.025300 24.8%

Non

- Hisp

- Other 0.029545 29.0% Nursing Infants 0.020956 20.5%

Non

- Nursing Infants 0.041450 40.6%
Female 13+ PREG 0.025006 24.5%
Children 1

- 6 0.064099 62.8%
Children 7

- 12 0.029443 28.9%
Male 13

- 19 0.019897 19.5%
Female 13

- 19/NP 0.020557 20.2%

Male 20+ 0.020948 20.5% Female 20+/NP 0.023959 23.5%

Seniors 55+ 0.022281 21.8%
All Infants 0.0351 22 34.4%
Female 13

- 50 0.023224 22.8%
Children 1

- 2 0.078752 77.2%
Children 3

- 5 0.059363 58.2%
Children 6

- 12 0.031987 31.4%
Youth 13

- 19 0.020237 19.8%
Adults 20

- 49 0.022612 22.2%
Adults 50

- 99 0.022504 22.1%
Female 13

- 49 0.023241 22.8%

-------------------------------------------------------------------------------