UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

MEMORANDUM 

Date: May 29, 2013 

OFFICE OF CHEMICAL SAFETY AND 

POLLUTION PREVENTION 

SUBJECT: Chlorantraniliprole Chronic Dietary (Food and Drinking Water) Exposure and 

Risk Assessment for the Section (3) Registration Action on Cereal Grains, Except 

Rice (Crop Group 15), Cereal Grain Forage (Crop Group 16), Pome Fruit (Crop 

Group ll-1 0), and Citrus (Crop Group 10-1 0) 

PC Code: 0901 00 

Decision No.: 467521 

Petition No.: 2E8064 

Risk Assessment Type: Dietary 

TXRNo.: N/A 

MRID No.: N/A 

DP Barcode: D411997 

Registration No.: 352-728, 352-729, 352-730 

Regulatory Action: Section 3 

Case No.: N/ A 

CAS No.: 500008-45-7 

40 CFR: § 180.628 

FROM: Kristin Rury, Biologist '¥--~ Risk Assessment Branch III ":- , (__) 

THROUGH: 

Health Effects Division (7509P) 

Ideliz 

Donna 

Negron-Encarnacion, 

Davis, Chemist d£ 

Cliemist 

/L~ ----

Dietary Exposure Science Advisory Counci ESAC) 

And 

Christine Olinger, Chief 

Risk Assessment Branch I 

Health Effects Division 

TO: Sheila Healy, Risk Assessor 

Risk Assessment Branch III 

Health Effects Division (7509P) 

And 

Venus Eagle, RM 0 1 
Chlorantraniliprole Dietary Exposure and Risk Assessment 

Insecticide/Rodenticide Branch (IRB) 

Registration Division (7505P) 

Executive Summary 

DP Number: 0411997 

A chronic aggregate dietary food and drinking water exposure and risk assessment was 

conducted using the Dietary Exposure Evaluation Model software with the Food Commodity 

Intake Database (DEEM-FCID) Version 3.16, which uses food consumption data collected from 

2003-2008 from the U.S. Department of Agriculture's National Health and Nutrition 

Examination Survey, What We Eat in America, (NHANES/WWEIA). The analysis was 

conducted to support a human health risk assessment for the proposed update of the existing 

citrus and pome fruit tolerances to correspond with new crop group definitions, a proposed 

tolerance increase on cereal grains, and new/modified tolerances for several livestock and 

poultry commodities. 

Acute Dietary Exposure Assessment: An acute dietary toxicity endpoint was not identified in the 

toxicity database for chlorantraniliprole; therefore, chlorantraniliprole does not pose an acute 

dietary risk and an acute dietary assessment is not required. 

Chronic Dietary Exposure Assessment: The chronic dietary (food and drinking water) exposure 

assessment for chlorantraniliprole assumed recommended and/or established tolerance level 

residues, 100% crop treated (%CT), and used DEEM default processing factors. Estimated 

drinking water concentrations (EDWCs) from the Environmental Fate and Effects Division 

(EFED) (39.87 ppb) were also included. The results of the chronic analysis indicate that chronic 

dietary (food and drinking water) exposure and risk does not exceed HED's level of concern 

[i.e., <1 00% chronic population adjusted dose ( cPAD)] for the U.S. population and all 

population subgroups. The resulting chronic dietary (food and drinking water) risk estimates 

were 2.1% of the cPAD for the general U.S. population and 6.3% for children 1-2, the most 

highly exposed population subgroup. 

Cancer Dietary Exposure Assessment: Chlorantraniliprole is classified as "Not Likely to be 

Carcinogenic to Humans"; therefore, a cancer dietary risk assessment was not performed. 

I. Introduction 

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide. For acute 

and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose 

(i.e., the dose that HED has concluded will result in no unreasonable adverse health effects). 

This dose is referred to as the population adjusted dose (PAD). The PAD is equivalent to the 

point of departure (POD, NOAEL, LOAEL, e.g.) divided by the required uncertainty or safety 

factors. 

For acute and non-cancer chronic exposures, HED is concerned when estimated dietary risk 

exceeds 100% ofthe PAD. HED is generally concerned when estimated cancer risk exceeds one 

in one million. References that discuss the acute and chronic risk assessments in more detail are 

available on the EPA/pesticides web site: "Available Information on Assessing Exposure from 

Page 2 of2 1 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

Page 3 of 21

Pesticides, A User’s Guide,” 21-JUN-2000, web link: http://www.epa.gov/fedrgstr/EPAPEST/2000/July/Day-12/6061.pdf; or see SOP 99.6 (20-AUG-1999).

The most recent dietary risk assessment for chlorantraniliprole was conducted by Cassi Walls 

(05/10/2012, D399530). 

II. Residue Information

Residues of Concern: Chlorantraniliprole is an insecticide that was developed by DuPont for 

control of lepidopteran pests. The residue of concern for tolerance enforcement in plants, 

livestock, and water is the parent compound. The residue of concern for risk assessment in 

plants is the parent compound. The residues of concern for risk assessment in ruminants are the 

parent compound, IN-HXH44, and IN-K9T00. The Risk Assessment team has decided that the 

residue of concern in poultry commodities for risk assessment will include the parent and the 

following metabolites: IN-H2H20, IN-K7H29, IN-F9N04, and IN-GAZ70. See Attachment 3 

for names and structures.

Established Tolerances: Permanent tolerances for chlorantraniliprole are currently established 

in/on a wide variety of crops (40 CFR §180.628). 

Recommended Tolerances: E.I. Du Pont de Nemours and Company (DuPont) has submitted an 

application for a proposed update of the existing citrus and pome fruit tolerances to correspond 

with new crop group definitions, and a proposed tolerance increase on cereal grains. The 

tolerance recommendations are outlined in Table 1. HED has required additional tolerances and 

tolerance increase on livestock commodities as shown in Table 1 according to the results of a 

newly submitted poultry feeding study and revised livestock dietary burdens based on the 

proposed uses on cereal grains. 

Residue Data used for Chronic Assessments: HED used tolerance level residues for the proposed 

and registered crops and 100% CT was used for all commodities included in this assessment; 

therefore, this assessment is considered conservative. Where processing data indicated a 

reduction (or no increase) in residue upon processing, the residue level of the RAC was used 

without reduction, for example mint oil from spearmint. Where processing data indicated an 

increase in residue in the processed commodity, a tolerance was established and used, e.g., 

raisins from grapes. Where adequate processing data did not exist, DEEM default concentration 

factors were used if available. DEEM default concentration factors were used for the following: 

dried apple, apple juice, dried apricot, dried banana, dried beef meat, cherry juice, fiddle corn 

syrup, cranberry juice, grape juice, grapefruit juice, lemon juice, lime juice, dried lychee, dried 

(dehydrated) bulb onion, orange juice, dried peach, dried pear, dried pineapple, pineapple juice, 

dried plantain, dried plum prune, plum juice, dried potato (flakes, granules), potato flour, 

tangerine juice, tomato paste, tomato puree, dried tomato, and tomato juice. Table 1 lists all 

changes to tolerance values and HED recommended tolerances for the proposed crops used in the 

dietary assessment. 

Meat, Milk, Poultry and Eggs: HED recently received a poultry feeding study (MRID 

48930706). Additionally, the livestock dietary burdens have been revised based on the proposed 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

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use on cereal grains. In consideration of the revised poultry dietary burden and the poultry 

feeding study, revised poultry tolerances are needed. The revisions to the livestock and poultry 

tolerances and dietary burdens are listed in Table 1. 

Table 1. Tolerance Summary for Chlorantraniliprole.

Commodity Existing 

Tolerance 

(ppm)

Proposed 

Tolerance 

(ppm)

Recommended 

Tolerance (ppm)

Comments; Correct Commodity 

Definition

180.628 (a) General

Grain, cereal, group 15, 

except rice

- 6.0 6.0 Grain, cereal, group15, except 

rice and corn.

Field corn grain, pop corn grain, 

and sweet corn must be excluded 

from the group as their tolerances 

are much lower than 6.0 resulting 

from the barley grain.

Grain, cereal, forage, 

fodder and straw, group 

16

-

30 40 OECD statistical calculation based 

on barley straw.

Fruit, citrus, group 10 1.4 Remove Remove Replaced by group 10-10

Fruit, citrus, group 10-

10

- 1.4 1.4 Crop group conversion.

Fruit, pome, group 11, 

except mayhaw

1.2 Remove Remove Replaced by group 11-10

Mayhaw 1.2 Remove Remove Replaced by group 11-10

Fruit, pome, group 11-

10

- 1.2 1.2 Crop group conversion.

Field corn forage 14 Remove Remove Replaced by crop group 16

Field corn grain 0.04 Remove 0.04 Retain, as 0.04 differs from the 

crop group 15 tolerance by a factor 

>5X.

Field corn milled 

byproducts

0.1 Remove 0.1 Corn, field, milled byproducts

Retain, in accordance with the 

retention of the field corn grain 

tolerance.

Pop corn forage 14 Remove Remove Replaced by crop group 16

Pop corn stover 14 Remove Remove Replaced by crop group 16

Sweet corn forage 14 Remove Remove Replaced by crop group 16

Sweet corn stover 14 Remove Remove Replaced by crop group 16

Cattle, liver 0.3 Remove Replace with Cattle, meat 

byproducts 

Cattle, meat byproducts 0.3 - 0.5 Cereal grain group 15 and group 

16 elevated the cattle dietary 

exposure.

Milk 0.05 - 0.1 Cereal grain group 15 and group 

16 elevated the cattle dietary 

exposure
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

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Table 1. Tolerance Summary for Chlorantraniliprole.

Commodity Existing 

Tolerance 

(ppm)

Proposed 

Tolerance 

(ppm)

Recommended 

Tolerance (ppm)

Comments; Correct Commodity 

Definition

Goat, liver 0.3 - Remove Replace with Goat, meat 

byproducts

Liver is grouped with other meat 

byproducts.

Horse, liver 0.3 - Remove Replace with Horse, meat 

byproducts

Liver is grouped with other meat 

byproducts.

Sheep, liver 0.3 - Remove Replace with Sheep, meat 

byproducts

Liver is grouped with other meat 

byproducts.

Hog, meat byproducts 0.02 - 0.05 Cereal grain group 15 elevated the 

hog dietary exposure.

Goat, meat byproducts, 

except liver

0.2 - 0.5 Replace with Goat, meat 

byproducts

Horse, meat 

byproducts, except liver

0.2 - 0.5 Replace with Horse, meat 

byproducts

Sheep, meat 

byproducts, except liver

0.2 - 0.5 Replace with Sheep, meat 

byproducts

Hog, meat - - 0.02 Cereal grain group 15 elevated the 

hog dietary exposure.

Hog, fat 0.02 - 0.05 Cereal grain group 15 elevated the 

hog dietary exposure.

Eggs 0.2 - 1.0 Cereal grain group 15 elevated the 

laying hen dietary exposure.

Poultry, meat 

byproducts

0.02 - 0.2 Cereal grain group 15 elevated the 

laying hen dietary exposure.

Poultry, meat - - 0.05 Cereal grain group 15 elevated the 

laying hen dietary exposure.

Poultry, fat 0.01 - 0.2 Cereal grain group 15 elevated the 

laying hen dietary exposure.

180.628(d) Indirect or inadvertent residues

Grain, cereal, forage, 

fodder and straw, group 

16

0.20 Expires 

04/10/14

Remove Replaced by crop group 16 as a 

primary crop.

III. Percent Crop Treated Information

The chronic dietary exposure assessment assumed 100% CT for all commodities. 

IV. Drinking Water Data

The drinking water residues used in the dietary risk assessment were provided by EFED (C. 

Koper, 01/17/2013, D404711; C. Koper, 2/29/2012, DP397882; and DP3881819, C. Koper, 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

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12/01/2010) and incorporated directly into this dietary assessment. Water residues were 

incorporated in the DEEM-FCID into the food categories “water, direct, all sources” and “water, 

indirect, all sources.” The estimated drinking water concentration (EDWC) for surface water 

from the previous estimate based on cranberries was 39.87 ppb and is higher than the current 

estimates based on the proposed uses. Thus, the surface water concentration of 39.87 ppb was 

used for this assessment and remains unchanged from the previous dietary assessment. This 

value of 39.87 ppb is the one in ten-year annual mean.

EDWCs for the chronic assessments were estimated using two EFED screening models: PRZMEXAMS and SCI-GROW, Version 2.3. The EDWCs from DP#3881819 are listed in Table 2. 

The model and its description are available at the EPA internet site: 

http://www.epa.gov/oppefed1/models/water/. 

Table 2. Summary of Estimated Surface Water and Groundwater Concentrations (EDWCs) for 

Chlorantraniliprole Used on Cranberries.

Surface Water 

Conc., ppb a

Groundwater Conc., 

ppb b

Acute 55.30

Chronic (non-cancer, 1 in 10 year annual average) 39.87 0.842

Chronic (cancer, 30-year annual average) 39.87

a

Pesticide Root Zone Model (PRZM v3.12.2, May 12, 2005) and Exposure Analysis Modeling System (EXAMS 

v2.98.04.06, April 25, 2005), simulation models, were coupled with the input PE5.pl.shell. The Provisional Cranberry 

Model was used to assess cranberry. The model does incorporate a degradation component

b

From the SCI-GROW model, assuming a maximum seasonal use rate of 0.200 lab ai/care (2 X 0.100 lb ai/acre), a Koc of 

153, and a half-life of 410 days from the aerobic soil metabolism study. 

V. DEEM-FCID Program and Consumption Information

Chlorantraniliprole chronic dietary exposure assessments were conducted using the Dietary 

Exposure Evaluation Model software with the Food Commodity Intake Database DEEM-FCID, 

Version 3.16, which incorporates consumption data from 2003 to 2008 from USDA’s 

NHANES/WWEIA. The data are based on the reported consumption of more than 20,000 

individuals over two non-consecutive survey days. Foods “as consumed” (e.g., apple pie) are 

linked to EPA-defined food commodities (e.g., apples, peeled fruit - cooked; fresh or N/S; baked; 

or wheat flour - cooked; fresh or N/S, baked) using publicly available recipe translation files 

developed jointly by USDA/ARS and EPA. For chronic exposure assessment, consumption data 

are averaged for the entire U.S. population and within population subgroups. However, for acute 

exposure assessment, consumption data are retained as individual consumption events. Based on 

analysis of the 2003-2008 WWEIA consumption data, which took into account dietary patterns 

and survey respondents, HED concluded that it is most appropriate to report risk for the 

following population subgroups: the general U.S. population, all infants (<1 year old), children 

1-2, children 3-5, children 6-12, youth 13-19, adults 20-49, females 13-49, and adults 50+ years 

old.

For a chronic dietary exposure assessment, an estimate of the residue level in each food or foodform (e.g., orange or orange juice) on the food commodity residue list is multiplied by the 

average daily consumption estimate for that food/food form to produce a residue intake estimate. 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

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The resulting residue intake estimate for each food/food form is summed with the residue intake 

estimates for all other food/food forms on the commodity residue list to arrive at the total 

average estimated exposure. Exposure is expressed in mg/kg body weight/day and as a percent 

of the cPAD. This procedure is performed for each population subgroup.

VI. Toxicological Information

The toxicity database for chlorantraniliprole is complete. No acute hazard, attributable to a single 

dose, was identified; therefore, an acute dietary endpoint was not selected for quantitative risk 

assessment. A composite uncertainty factor of 100 to account for interspecies extrapolation and 

intraspecies variability is applied to the no observed adverse effect level (NOAEL) to derive a 

cPAD of 1.58 mg/kg/day.

The chlorantraniliprole risk assessment team evaluated the quality of the toxicity and exposure 

data and, based on these data, recommended that the FQPA Safety Factor be reduced to 1X. 

Based on the weight of evidence of the available scientific data, and in accordance with EPA’s 

Final Guidelines for Carcinogen Risk Assessment (March 2005), chlorantraniliprole may be 

classified as “Not Likely to Be Carcinogenic to Humans.”

The toxicity endpoints pertinent for human risk assessment are summarized in Table 3.

Table 3. Summary of Toxicological Doses and Endpoints for Chlorantraniliprole for Use in Dietary Human 

Health Risk Assessments.

Exposure/

Scenario

Point of 

Departure

Uncertainty/FQPA 

Safety Factors

RfD, PAD, 

Level of 

Concern for 

Risk 

Assessment

Study and Toxicological Effects

Acute Dietary 

(All 

Populations)

NA NA NA

No acute hazard, attributable to a 

single dose, was identified; therefore, 

an acute dietary endpoint was not 

selected for quantitative risk 

assessment.

Chronic 

Dietary (All 

Populations)

NOAEL= 

158 

mg/kg/day

UFA= 10x

UFH=10x

FQPA SF= 1x

Chronic RfD 

= 1.58 

mg/kg/day

cPAD = 1.58 

mg/kg/day

18-Month Oral (feeding)/mouse

LOAEL = 935 mg/kg/day based on 

eosinophilic foci accompanied by 

hepatocellular hypertrophy and 

increased liver weight (males only).

Cancer (oral, 

dermal, 

inhalation)

Classification: “Not likely to be Carcinogenic to Humans” based on weight of evidence of data: 

no treatment-related tumors were reported in the submitted chronic and oncogenicity studies in 

rats and mice or in the subchronic studies in mice, dogs and rats; and no mutagenic concern was 

reported in the genotoxicity studies. 

Abbreviations: UF = uncertainty factor, UFA = extrapolation from animal to human (interspecies), UFH = potential variation in 

sensitivity among members of the human population (intraspecies), UFFQPA = FQPA Safety Factor, NOAEL = no-observed 

adverse-effect level, LOAEL = lowest-observed adverse-effect level, RfD = reference dose (a = acute, c = chronic), PAD = 

population-adjusted dose, LOC = level of concern.

VII. Results/Discussion 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

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As stated above, for chronic assessments, HED is concerned when dietary risk exceeds 100% of 

the PAD. The DEEM-FCID analyses estimate the dietary exposure of the U.S. population and 

various population subgroups. The results reported in Table 4 are for the general U.S. 

Population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 13-19, 

females 13-49, adults 20-49, and adults 50+ years. 

Results of Chronic Dietary (Food and Drinking Water) Exposure Analysis: The results of the 

chronic dietary exposure analysis are reported in the summary table below. 

Table 4. Summary of Dietary (Food and Drinking Water) Exposure and Risk for Chlorantraniliprole.

Population Subgroup

Chronic Dietary

Dietary Exposure

(mg/kg/day) % cPAD*

General U.S. Population 0.032474 2.1

All Infants (<1 year old) 0.051597 3.3

Children 1-2 years old* 0.099596 6.3

Children 3-5 years old 0.076426 4.8

Children 6-12 years old 0.042431 2.7

Youth 13-19 years old 0.024386 1.5

Adults 20-49 years old 0.026971 1.7

Adults 50+ years old 0.026545 1.7

Females 13-49 years old 0.025763 1.6

*The subpopulation(s) with the highest risk estimates (Insert an asterisk after the population subgroups with the 

highest risk estimates and highlight the subpopulations in bold print)

Report %PADs to 2 significant figures unless the value is <1, in which case you should report it as <1.

VIII. Characterization of Inputs/Outputs

The chlorantraniliprole dietary exposure risk estimates are unrefined and considered conservative 

since they: (1) assume that 100% of the registered/proposed crops were treated with 

chlorantraniliprole; (2) use established or recommended tolerance level residues for all crops; (3) 

use default/conservative processing factors for processed commodities; and (4) use conservative, 

modeled drinking water estimates. The tolerances are derived from crop field trials or 

conservative data translations and default processing factors. The field trials were conducted at 

maximum application rates and minimum pre-harvest intervals, or residues were extrapolated to 

1X the use rate for tolerance recommendations. Additional refinements to the assessment could 

include use of %CT information and any available monitoring data. However, at this time, the 

dietary risks (food and water) of chlorantraniliprole are < 6.3% and are not of concern to HED; 

therefore no further refinement is required. 

IX. Conclusions

A conservative dietary (food and drinking water) exposure and risk assessment was performed 

for chlorantraniliprole. The assumptions incorporated into the assessment included 100% CT, 

default processing factors, established/proposed tolerance level residues, and conservative 

EDWCs. The chronic dietary (food and drinking water) exposure estimates are below HED’s 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

Page 9 of 21

level of concern (<100% cPAD) for the general U.S. population and all population subgroups. 

Chlorantraniliprole dietary (food and drinking water) risk is 2.1% of the cPAD for the general 

U.S. population and 6.3% for children 1-2 years old, the most highly exposed population 

subgroup. HED is confident that the assessment does not underestimate risk to the general U.S. 

population or any population subgroup.

X. List of Attachments

Chronic Residue Input file

Chronic Results File

Structures of Chlorantraniliprole and Possible Metabolites 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

Page 10 of 21

Attachment 1: Chronic Food Plus Water Input File 

ilename: C:\Documents and Settings\krury\My Documents\My Work 

Files\Chlorantraniliprole\DEEM Files\CHLORANTRANILIPROLECHRONIC cereal grains pome fruit 

stone fruit 42413.R08

Chemical: chlorantraniliprole

RfD(Chronic): 1.58 mg/kg bw/day NOEL(Chronic): 158 mg/kg bw/day

RfD(Acute): 0 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/day

Date created/last modified: 04-24-2013/12:50:37 Program ver. 3.16, 03-08-d

Comment: Only a chronic endpoint; there is no acute endpoint

-----------------------------------------------------------------------------------

 EPA Crop Def Res Adj.Factors Comment

 Code Grp Commodity Name (ppm) #1 #2 

---------- ---- ------------------------------- ---------- ------ ------ -------

0101050000 1AB Beet, garden, roots 0.300000 1.000 1.000 

0101050001 1AB Beet, garden, roots-babyfood 0.300000 1.000 1.000 

0101052000 1A Beet, sugar 0.300000 1.000 1.000 

0101052001 1A Beet, sugar-babyfood 0.300000 1.000 1.000 

0101053000 1A Beet, sugar, molasses 9.000000 1.000 1.000 

0101053001 1A Beet, sugar, molasses-babyfood 9.000000 1.000 1.000 

0101067000 1AB Burdock 0.300000 1.000 1.000 

0101078000 1AB Carrot 0.300000 1.000 1.000 

0101078001 1AB Carrot-babyfood 0.300000 1.000 1.000 

0101079000 1AB Carrot, juice 0.300000 1.000 1.000 

0101084000 1AB Celeriac 0.300000 1.000 1.000 

0101100000 1AB Chicory, roots 0.300000 1.000 1.000 

0101168000 1AB Ginseng, dried 0.300000 1.000 1.000 

0101190000 1AB Horseradish 0.300000 1.000 1.000 

0101250000 1AB Parsley, turnip rooted 0.300000 1.000 1.000 

0101251000 1AB Parsnip 0.300000 1.000 1.000 

0101251001 1AB Parsnip-babyfood 0.300000 1.000 1.000 

0101314000 1AB Radish, roots 0.300000 1.000 1.000 

0101316000 1AB Radish, Oriental, roots 0.300000 1.000 1.000 

0101327000 1AB Rutabaga 0.300000 1.000 1.000 

0101331000 1AB Salsify, roots 0.300000 1.000 1.000 

0101388000 1AB Turnip, roots 0.300000 1.000 1.000 

0103015000 1CD Arrowroot, flour 0.300000 1.000 1.000 

0103015001 1CD Arrowroot, flour-babyfood 0.300000 1.000 1.000 

0103017000 1CD Artichoke, Jerusalem 0.300000 1.000 1.000 

0103082000 1CD Cassava 0.300000 1.000 1.000 

0103082001 1CD Cassava-babyfood 0.300000 1.000 1.000 

0103139000 1CD Dasheen, corm 0.300000 1.000 1.000 

0103166000 1CD Ginger 0.300000 1.000 1.000 

0103166001 1CD Ginger-babyfood 0.300000 1.000 1.000 

0103167000 1CD Ginger, dried 0.300000 1.000 1.000 

0103296000 1C Potato, chips 0.300000 1.000 1.000 

0103297000 1C Potato, dry (granules/ flakes) 0.300000 6.500 1.000 

0103297001 1C Potato, dry (granules/ flakes)-b 0.300000 6.500 1.000 

0103298000 1C Potato, flour 0.300000 6.500 1.000 

0103298001 1C Potato, flour-babyfood 0.300000 6.500 1.000 

0103299000 1C Potato, tuber, w/peel 0.300000 1.000 1.000 

0103299001 1C Potato, tuber, w/peel-babyfood 0.300000 1.000 1.000 

0103300000 1C Potato, tuber, w/o peel 0.300000 1.000 1.000 

0103300001 1C Potato, tuber, w/o peel-babyfood 0.300000 1.000 1.000 

0103366000 1CD Sweet potato 0.300000 1.000 1.000 

0103366001 1CD Sweet potato-babyfood 0.300000 1.000 1.000 

0103371000 1CD Tanier, corm 0.300000 1.000 1.000 

0103387000 1CD Turmeric 0.300000 1.000 1.000 

0103406000 1CD Yam, true 0.300000 1.000 1.000 

0103407000 1CD Yam bean 0.300000 1.000 1.000 

0200051000 2 Beet, garden, tops 40.000000 1.000 1.000 

0200101000 2 Chicory, tops 40.000000 1.000 1.000 

0200140000 2 Dasheen, leaves 40.000000 1.000 1.000 

0200315000 2 Radish, tops 40.000000 1.000 1.000 

0200317000 2 Radish, Oriental, tops 40.000000 1.000 1.000 

0200332000 2 Salsify, tops 40.000000 1.000 1.000 

0301165000 3A Garlic, bulb 0.300000 1.000 1.000 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

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0301165001 3A Garlic, bulb-babyfood 0.300000 1.000 1.000 

0301237000 3A Onion, bulb 0.300000 1.000 1.000 

0301237001 3A Onion, bulb-babyfood 0.300000 1.000 1.000 

0301238000 3A Onion, bulb, dried 0.300000 9.000 1.000 

0301238001 3A Onion, bulb, dried-babyfood 0.300000 9.000 1.000 

0302103000 3B Chive, fresh leaves 25.000000 1.000 1.000 

0302198000 3B Leek 0.300000 1.000 1.000 

0302338500 3B Shallot, fresh leaves 0.300000 1.000 1.000 

0401005000 4A Amaranth, leafy 13.000000 1.000 1.000 

0401018000 4A Arugula 13.000000 1.000 1.000 

0401104000 4A Chrysanthemum, garland 13.000000 1.000 1.000 

0401133000 4A Cress, garden 13.000000 1.000 1.000 

0401134000 4A Cress, upland 13.000000 1.000 1.000 

0401138000 4A Dandelion, leaves 13.000000 1.000 1.000 

0401150000 4A Endive 13.000000 1.000 1.000 

0401204000 4A Lettuce, head 13.000000 1.000 1.000 

0401205000 4A Lettuce, leaf 13.000000 1.000 1.000 

0401248000 4A Parsley, leaves 13.000000 1.000 1.000 

0401313000 4A Radicchio 13.000000 1.000 1.000 

0401355000 4A Spinach 13.000000 1.000 1.000 

0401355001 4A Spinach-babyfood 13.000000 1.000 1.000 

0402076000 4B Cardoon 13.000000 1.000 1.000 

0402085000 4B Celery 13.000000 1.000 1.000 

0402085001 4B Celery-babyfood 13.000000 1.000 1.000 

0402086000 4B Celery, juice 13.000000 1.000 1.000 

0402087000 4B Celtuce 13.000000 1.000 1.000 

0402152000 4B Fennel, Florence 13.000000 1.000 1.000 

0402322000 4B Rhubarb 13.000000 1.000 1.000 

0402367000 4B Swiss chard 13.000000 1.000 1.000 

0501061000 5A Broccoli 4.000000 1.000 1.000 

0501061001 5A Broccoli-babyfood 4.000000 1.000 1.000 

0501062000 5A Broccoli, Chinese 4.000000 1.000 1.000 

0501064000 5A Brussels sprouts 4.000000 1.000 1.000 

0501069000 5A Cabbage 4.000000 1.000 1.000 

0501071000 5A Cabbage, Chinese, napa 4.000000 1.000 1.000 

0501072000 5A Cabbage, Chinese, mustard 4.000000 1.000 1.000 

0501083000 5A Cauliflower 4.000000 1.000 1.000 

0501196000 5A Kohlrabi 4.000000 1.000 1.000 

0502063000 5B Broccoli raab 11.000000 1.000 1.000 

0502070000 5B Cabbage, Chinese, bok choy 11.000000 1.000 1.000 

0502117000 5B Collards 11.000000 1.000 1.000 

0502194000 5B Kale 11.000000 1.000 1.000 

0502229000 5B Mustard greens 11.000000 1.000 1.000 

0502318000 5B Rape greens 11.000000 1.000 1.000 

0502389000 5B Turnip, greens 11.000000 1.000 1.000 

0600347000 6 Soybean, seed 2.000000 1.000 1.000 

0600349000 6 Soybean, soy milk 2.000000 1.000 1.000 

0600349001 6 Soybean, soy milk-babyfood or in 2.000000 1.000 1.000 

0600350000 6 Soybean, oil 2.000000 1.000 1.000 

0600350001 6 Soybean, oil-babyfood 2.000000 1.000 1.000 

0601043000 6A Bean, snap, succulent 2.000000 1.000 1.000 

0601043001 6A Bean, snap, succulent-babyfood 2.000000 1.000 1.000 

0601257000 6A Pea, edible podded, succulent 2.000000 1.000 1.000 

0602031000 6B Bean, broad, succulent 2.000000 1.000 1.000 

0602033000 6B Bean, cowpea, succulent 2.000000 1.000 1.000 

0602037000 6B Bean, lima, succulent 2.000000 1.000 1.000 

0602255000 6B Pea, succulent 2.000000 1.000 1.000 

0602255001 6B Pea, succulent-babyfood 2.000000 1.000 1.000 

0602259000 6B Pea, pigeon, succulent 2.000000 1.000 1.000 

0603030000 6C Bean, black, seed 2.000000 1.000 1.000 

0603032000 6C Bean, broad, seed 2.000000 1.000 1.000 

0603034000 6C Bean, cowpea, seed 2.000000 1.000 1.000 

0603035000 6C Bean, great northern, seed 2.000000 1.000 1.000 

0603036000 6C Bean, kidney, seed 2.000000 1.000 1.000 

0603038000 6C Bean, lima, seed 2.000000 1.000 1.000 

0603039000 6C Bean, mung, seed 2.000000 1.000 1.000 

0603040000 6C Bean, navy, seed 2.000000 1.000 1.000 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

Page 12 of 21

0603041000 6C Bean, pink, seed 2.000000 1.000 1.000 

0603042000 6C Bean, pinto, seed 2.000000 1.000 1.000 

0603098000 6C Chickpea, seed 2.000000 1.000 1.000 

0603098001 6C Chickpea, seed-babyfood 2.000000 1.000 1.000 

0603099000 6C Chickpea, flour 2.000000 1.000 1.000 

0603182000 6C Guar, seed 2.000000 1.000 1.000 

0603182001 6C Guar, seed-babyfood 2.000000 1.000 1.000 

0603203000 6C Lentil, seed 2.000000 1.000 1.000 

0603256000 6C Pea, dry 2.000000 1.000 1.000 

0603256001 6C Pea, dry-babyfood 2.000000 1.000 1.000 

0603258000 6C Pea, pigeon, seed 2.000000 1.000 1.000 

0603348000 6C Soybean, flour 2.000000 1.000 1.000 

0603348001 6C Soybean, flour-babyfood 2.000000 1.000 1.000 

0801374000 8A Tomatillo 1.400000 1.000 1.000 

0801375000 8A Tomato 1.400000 1.000 1.000 

0801375001 8A Tomato-babyfood 1.400000 1.000 1.000 

0801376000 8A Tomato, paste 1.400000 5.400 1.000 

0801376001 8A Tomato, paste-babyfood 1.400000 5.400 1.000 

0801377000 8A Tomato, puree 1.400000 3.300 1.000 

0801377001 8A Tomato, puree-babyfood 1.400000 3.300 1.000 

0801378000 8A Tomato, dried 1.400000 14.300 1.000 

0801378001 8A Tomato, dried-babyfood 1.400000 14.300 1.000 

0801379000 8A Tomato, juice 1.400000 1.500 1.000 

0802148000 8BC Eggplant 1.400000 1.000 1.000 

0802234000 8BC Okra 1.400000 1.000 1.000 

0802270000 8B Pepper, bell 1.400000 1.000 1.000 

0802270001 8B Pepper, bell-babyfood 1.400000 1.000 1.000 

0802271000 8B Pepper, bell, dried 1.400000 1.000 1.000 

0802271001 8B Pepper, bell, dried-babyfood 1.400000 1.000 1.000 

0802272000 8BC Pepper, nonbell 1.400000 1.000 1.000 

0802272001 8BC Pepper, nonbell-babyfood 1.400000 1.000 1.000 

0802273000 8BC Pepper, nonbell, dried 1.400000 1.000 1.000 

0901075000 9A Cantaloupe 0.500000 1.000 1.000 

0901187000 9A Honeydew melon 0.500000 1.000 1.000 

0901399000 9A Watermelon 0.500000 1.000 1.000 

0901400000 9A Watermelon, juice 0.500000 1.000 1.000 

0902021000 9B Balsam pear 0.500000 1.000 1.000 

0902088000 9B Chayote, fruit 0.500000 1.000 1.000 

0902102000 9B Chinese waxgourd 0.500000 1.000 1.000 

0902135000 9B Cucumber 0.500000 1.000 1.000 

0902308000 9B Pumpkin 0.500000 1.000 1.000 

0902309000 9B Pumpkin, seed 0.500000 1.000 1.000 

0902356000 9B Squash, summer 0.500000 1.000 1.000 

0902356001 9B Squash, summer-babyfood 0.500000 1.000 1.000 

0902357000 9B Squash, winter 0.500000 1.000 1.000 

0902357001 9B Squash, winter-babyfood 0.500000 1.000 1.000 

1001106000 10A Citron 1.400000 1.000 1.000 

1001107000 10A Citrus hybrids 1.400000 1.000 1.000 

1001108000 10A Citrus, oil 1.400000 1.000 1.000 

1001240000 10A Orange 1.400000 1.000 1.000 

1001241000 10A Orange, juice 1.400000 1.800 1.000 

1001241001 10A Orange, juice-babyfood 1.400000 1.800 1.000 

1001242000 10A Orange, peel 1.400000 1.000 1.000 

1001369000 10A Tangerine 1.400000 1.000 1.000 

1001370000 10A Tangerine, juice 1.400000 2.300 1.000 

1002197000 10B Kumquat 1.400000 1.000 1.000 

1002199000 10B Lemon 1.400000 1.000 1.000 

1002200000 10B Lemon, juice 1.400000 2.000 1.000 

1002200001 10B Lemon, juice-babyfood 1.400000 2.000 1.000 

1002201000 10B Lemon, peel 1.400000 1.000 1.000 

1002206000 10B Lime 1.400000 1.000 1.000 

1002207000 10B Lime, juice 1.400000 2.000 1.000 

1002207001 10B Lime, juice-babyfood 1.400000 2.000 1.000 

1003180000 10C Grapefruit 1.400000 1.000 1.000 

1003181000 10C Grapefruit, juice 1.400000 2.100 1.000 

1003307000 10C Pummelo 1.400000 1.000 1.000 

1100007000 11 Apple, fruit with peel 1.200000 1.000 1.000 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

Page 13 of 21

1100008000 11 Apple, peeled fruit 1.200000 1.000 1.000 

1100008001 11 Apple, peeled fruit-babyfood 1.200000 1.000 1.000 

1100009000 11 Apple, dried 1.200000 8.000 1.000 

1100009001 11 Apple, dried-babyfood 1.200000 8.000 1.000 

1100010000 11 Apple, juice 1.200000 1.300 1.000 

1100010001 11 Apple, juice-babyfood 1.200000 1.300 1.000 

1100011000 11 Apple, sauce 1.200000 1.000 1.000 

1100011001 11 Apple, sauce-babyfood 1.200000 1.000 1.000 

1100129000 11 Crabapple 1.200000 1.000 1.000 

1100173500 11 Goji berry 1.200000 1.000 1.000 

1100210000 11 Loquat 1.200000 1.000 1.000 

1100266000 11 Pear 1.200000 1.000 1.000 

1100266001 11 Pear-babyfood 1.200000 1.000 1.000 

1100267000 11 Pear, dried 1.200000 6.250 1.000 

1100268000 11 Pear, juice 1.200000 1.000 1.000 

1100268001 11 Pear, juice-babyfood 1.200000 1.000 1.000 

1100310000 11 Quince 1.200000 1.000 1.000 

1201090000 12A Cherry 2.000000 1.000 1.000 

1201090001 12A Cherry-babyfood 2.000000 1.000 1.000 

1201091000 12A Cherry, juice 2.000000 1.500 1.000 

1201091001 12A Cherry, juice-babyfood 2.000000 1.500 1.000 

1202012000 12B Apricot 4.000000 1.000 1.000 

1202012001 12B Apricot-babyfood 4.000000 1.000 1.000 

1202013000 12B Apricot, dried 4.000000 6.000 1.000 

1202014000 12B Apricot, juice 4.000000 1.000 1.000 

1202014001 12B Apricot, juice-babyfood 4.000000 1.000 1.000 

1202230000 12B Nectarine 4.000000 1.000 1.000 

1202260000 12B Peach 4.000000 1.000 1.000 

1202260001 12B Peach-babyfood 4.000000 1.000 1.000 

1202261000 12B Peach, dried 4.000000 7.000 1.000 

1202261001 12B Peach, dried-babyfood 4.000000 7.000 1.000 

1202262000 12B Peach, juice 4.000000 1.000 1.000 

1202262001 12B Peach, juice-babyfood 4.000000 1.000 1.000 

1203285000 12C Plum 4.000000 1.000 1.000 

1203285001 12C Plum-babyfood 4.000000 1.000 1.000 

1203286000 12C Plum, prune, fresh 4.000000 1.000 1.000 

1203286001 12C Plum, prune, fresh-babyfood 4.000000 1.000 1.000 

1203287000 12C Plum, prune, dried 4.000000 5.000 1.000 

1203287001 12C Plum, prune, dried-babyfood 4.000000 5.000 1.000 

1203288000 12C Plum, prune, juice 4.000000 1.400 1.000 

1203288001 12C Plum, prune, juice-babyfood 4.000000 1.400 1.000 

1301055000 13A Blackberry 1.800000 1.000 1.000 

1301056000 13A Blackberry, juice 1.800000 1.000 1.000 

1301056001 13A Blackberry, juice-babyfood 1.800000 1.000 1.000 

1301058000 13A Boysenberry 1.800000 1.000 1.000 

1301208000 13A Loganberry 1.800000 1.000 1.000 

1301320000 13A Raspberry 1.800000 1.000 1.000 

1301320001 13A Raspberry-babyfood 1.800000 1.000 1.000 

1301321000 13A Raspberry, juice 1.800000 1.000 1.000 

1301321001 13A Raspberry, juice-babyfood 1.800000 1.000 1.000 

1302057000 13B Blueberry 2.500000 1.000 1.000 

1302057001 13B Blueberry-babyfood 2.500000 1.000 1.000 

1302136000 13B Currant 2.500000 1.000 1.000 

1302137000 13B Currant, dried 2.500000 1.000 1.000 

1302149000 13B Elderberry 2.500000 1.000 1.000 

1302174000 13B Gooseberry 2.500000 1.000 1.000 

1302191000 13B Huckleberry 2.500000 1.000 1.000 

1303227000 13C Mulberry 2.500000 1.000 1.000 

1304175000 13D Grape 2.500000 1.000 1.000 

1304176000 13D Grape, juice 2.500000 1.200 1.000 

1304176001 13D Grape, juice-babyfood 2.500000 1.200 1.000 

1304179000 13D Grape, wine and sherry 2.500000 1.000 1.000 

1307130000 13G Cranberry 1.000000 1.000 1.000 

1307130001 13G Cranberry-babyfood 1.000000 1.000 1.000 

1307131000 13G Cranberry, dried 1.000000 1.000 1.000 

1307132000 13G Cranberry, juice 1.000000 1.100 1.000 

1307132001 13G Cranberry, juice-babyfood 1.000000 1.100 1.000 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

Page 14 of 21

1307359000 13G Strawberry 1.000000 1.000 1.000 

1307359001 13G Strawberry-babyfood 1.000000 1.000 1.000 

1307360000 13G Strawberry, juice 1.000000 1.000 1.000 

1307360001 13G Strawberry, juice-babyfood 1.000000 1.000 1.000 

1400003000 14 Almond 0.040000 1.000 1.000 

1400003001 14 Almond-babyfood 0.040000 1.000 1.000 

1400004000 14 Almond, oil 0.040000 1.000 1.000 

1400004001 14 Almond, oil-babyfood 0.040000 1.000 1.000 

1400059000 14 Brazil nut 0.040000 1.000 1.000 

1400068000 14 Butternut 0.040000 1.000 1.000 

1400081000 14 Cashew 0.040000 1.000 1.000 

1400092000 14 Chestnut 0.040000 1.000 1.000 

1400155000 14 Hazelnut 0.040000 1.000 1.000 

1400156000 14 Hazelnut, oil 0.040000 1.000 1.000 

1400185000 14 Hickory nut 0.040000 1.000 1.000 

1400213000 14 Macadamia nut 0.040000 1.000 1.000 

1400269000 14 Pecan 0.040000 1.000 1.000 

1400282000 14 Pistachio 0.040000 1.000 1.000 

1400391000 14 Walnut 0.040000 1.000 1.000 

1500025000 15 Barley, pearled barley 6.000000 1.000 1.000 

1500025001 15 Barley, pearled barley-babyfood 6.000000 1.000 1.000 

1500026000 15 Barley, flour 6.000000 1.000 1.000 

1500026001 15 Barley, flour-babyfood 6.000000 1.000 1.000 

1500027000 15 Barley, bran 6.000000 1.000 1.000 

1500065000 15 Buckwheat 6.000000 1.000 1.000 

1500066000 15 Buckwheat, flour 6.000000 1.000 1.000 

1500120000 15 Corn, field, flour 0.040000 1.000 1.000 

1500120001 15 Corn, field, flour-babyfood 0.040000 1.000 1.000 

1500121000 15 Corn, field, meal 0.040000 1.000 1.000 

1500121001 15 Corn, field, meal-babyfood 0.040000 1.000 1.000 

1500122000 15 Corn, field, bran 0.040000 1.000 1.000 

1500123000 15 Corn, field, starch 0.040000 1.000 1.000 

1500123001 15 Corn, field, starch-babyfood 0.040000 1.000 1.000 

1500124000 15 Corn, field, syrup 0.040000 1.500 1.000 

1500124001 15 Corn, field, syrup-babyfood 0.040000 1.500 1.000 

1500125000 15 Corn, field, oil 0.040000 1.000 1.000 

1500125001 15 Corn, field, oil-babyfood 0.040000 1.000 1.000 

1500126000 15 Corn, pop 0.040000 1.000 1.000 

1500127000 15 Corn, sweet 0.040000 1.000 1.000 

1500127001 15 Corn, sweet-babyfood 0.040000 1.000 1.000 

1500226000 15 Millet, grain 6.000000 1.000 1.000 

1500231000 15 Oat, bran 6.000000 1.000 1.000 

1500232000 15 Oat, flour 6.000000 1.000 1.000 

1500232001 15 Oat, flour-babyfood 6.000000 1.000 1.000 

1500233000 15 Oat, groats/rolled oats 6.000000 1.000 1.000 

1500233001 15 Oat, groats/rolled oats-babyfood 6.000000 1.000 1.000 

1500323000 15 Rice, white 0.150000 1.000 1.000 

1500323001 15 Rice, white-babyfood 0.150000 1.000 1.000 

1500324000 15 Rice, brown 0.150000 1.000 1.000 

1500324001 15 Rice, brown-babyfood 0.150000 1.000 1.000 

1500325000 15 Rice, flour 0.150000 1.000 1.000 

1500325001 15 Rice, flour-babyfood 0.150000 1.000 1.000 

1500326000 15 Rice, bran 0.150000 1.000 1.000 

1500326001 15 Rice, bran-babyfood 0.150000 1.000 1.000 

1500328000 15 Rye, grain 6.000000 1.000 1.000 

1500329000 15 Rye, flour 6.000000 1.000 1.000 

1500344000 15 Sorghum, grain 6.000000 1.000 1.000 

1500345000 15 Sorghum, syrup 6.000000 1.000 1.000 

1500381000 15 Triticale, flour 6.000000 1.000 1.000 

1500381001 15 Triticale, flour-babyfood 6.000000 1.000 1.000 

1500401000 15 Wheat, grain 6.000000 1.000 1.000 

1500401001 15 Wheat, grain-babyfood 6.000000 1.000 1.000 

1500402000 15 Wheat, flour 0.160000 1.000 1.000 

1500402001 15 Wheat, flour-babyfood 0.160000 1.000 1.000 

1500403000 15 Wheat, germ 0.490000 1.000 1.000 

1500404000 15 Wheat, bran 0.450000 1.000 1.000 

1500405000 15 Wild rice 0.150000 1.000 1.000 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

Page 15 of 21

1800002000 18 Alfalfa, seed 7.000000 1.000 1.000 

1901028000 19A Basil, fresh leaves 25.000000 1.000 1.000 

1901028001 19A Basil, fresh leaves-babyfood 25.000000 1.000 1.000 

1901029000 19A Basil, dried leaves 90.000000 1.000 1.000 

1901029001 19A Basil, dried leaves-babyfood 90.000000 1.000 1.000 

1901118000 19A Cilantro, leaves 25.000000 1.000 1.000 

1901118001 19A Cilantro, leaves-babyfood 25.000000 1.000 1.000 

1901144000 19A Dillweed 25.000000 1.000 1.000 

1901184000 19A Herbs, other 25.000000 1.000 1.000 

1901184001 19A Herbs, other-babyfood 25.000000 1.000 1.000 

1901202000 19A Lemongrass 25.000000 1.000 1.000 

1901220000 19A Marjoram 25.000000 1.000 1.000 

1901220001 19A Marjoram-babyfood 25.000000 1.000 1.000 

1901249000 19A Parsley, dried leaves 90.000000 1.000 1.000 

1901249001 19A Parsley, dried leaves-babyfood 90.000000 1.000 1.000 

1901334000 19A Savory 25.000000 1.000 1.000 

1902105000 19B Cinnamon 14.000000 1.000 1.000 

1902105001 19B Cinnamon-babyfood 14.000000 1.000 1.000 

1902119000 19B Coriander, seed 14.000000 1.000 1.000 

1902119001 19B Coriander, seed-babyfood 14.000000 1.000 1.000 

1902143000 19B Dill, seed 14.000000 1.000 1.000 

1902274000 19B Pepper, black and white 14.000000 1.000 1.000 

1902274001 19B Pepper, black and white-babyfood 14.000000 1.000 1.000 

1902354000 19B Spices, other 14.000000 1.000 1.000 

1902354001 19B Spices, other-babyfood 14.000000 1.000 1.000 

2001163000 20A Flax seed, oil 2.000000 1.000 1.000 

2001319000 20A Rapeseed, oil 2.000000 1.000 1.000 

2001319001 20A Rapeseed, oil-babyfood 2.000000 1.000 1.000 

2001336000 20A Sesame, seed 0.300000 1.000 1.000 

2001336001 20A Sesame, seed-babyfood 0.300000 1.000 1.000 

2001337000 20A Sesame, oil 0.300000 1.000 1.000 

2001337001 20A Sesame, oil-babyfood 0.300000 1.000 1.000 

2002330000 20B Safflower, oil 2.000000 1.000 1.000 

2002330001 20B Safflower, oil-babyfood 2.000000 1.000 1.000 

2002364000 20B Sunflower, seed 2.000000 1.000 1.000 

2002365000 20B Sunflower, oil 2.000000 1.000 1.000 

2002365001 20B Sunflower, oil-babyfood 2.000000 1.000 1.000 

2003128000 20C Cottonseed, oil 0.300000 1.000 1.000 

2003128001 20C Cottonseed, oil-babyfood 0.300000 1.000 1.000 

3100044000 31 Beef, meat 0.100000 1.000 1.000 

3100044001 31 Beef, meat-babyfood 0.100000 1.000 1.000 

3100045000 31 Beef, meat, dried 0.100000 1.920 1.000 

3100046000 31 Beef, meat byproducts 0.500000 1.000 1.000 

3100046001 31 Beef, meat byproducts-babyfood 0.500000 1.000 1.000 

3100047000 31 Beef, fat 0.500000 1.000 1.000 

3100047001 31 Beef, fat-babyfood 0.500000 1.000 1.000 

3100048000 31 Beef, kidney 0.500000 1.000 1.000 

3100049000 31 Beef, liver 0.500000 1.000 1.000 

3100049001 31 Beef, liver-babyfood 0.500000 1.000 1.000 

3200169000 32 Goat, meat 0.100000 1.000 1.000 

3200170000 32 Goat, meat byproducts 0.500000 1.000 1.000 

3200171000 32 Goat, fat 0.500000 1.000 1.000 

3200172000 32 Goat, kidney 0.500000 1.000 1.000 

3200173000 32 Goat, liver 0.500000 1.000 1.000 

3300189000 33 Horse, meat 0.100000 1.000 1.000 

3400290000 34 Pork, meat 0.020000 1.000 1.000 

3400290001 34 Pork, meat-babyfood 0.020000 1.000 1.000 

3400291000 34 Pork, skin 0.050000 1.000 1.000 

3400292000 34 Pork, meat byproducts 0.050000 1.000 1.000 

3400292001 34 Pork, meat byproducts-babyfood 0.050000 1.000 1.000 

3400293000 34 Pork, fat 0.050000 1.000 1.000 

3400293001 34 Pork, fat-babyfood 0.050000 1.000 1.000 

3400294000 34 Pork, kidney 0.050000 1.000 1.000 

3400295000 34 Pork, liver 0.050000 1.000 1.000 

3500339000 35 Sheep, meat 0.100000 1.000 1.000 

3500339001 35 Sheep, meat-babyfood 0.100000 1.000 1.000 

3500340000 35 Sheep, meat byproducts 0.500000 1.000 1.000 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

Page 16 of 21

3500341000 35 Sheep, fat 0.500000 1.000 1.000 

3500341001 35 Sheep, fat-babyfood 0.500000 1.000 1.000 

3500342000 35 Sheep, kidney 0.500000 1.000 1.000 

3500343000 35 Sheep, liver 0.500000 1.000 1.000 

3600222000 36 Milk, fat 0.100000 1.000 1.000 

3600222001 36 Milk, fat-baby food/infant formu 0.100000 1.000 1.000 

3600223000 36 Milk, nonfat solids 0.100000 1.000 1.000 

3600223001 36 Milk, nonfat solids-baby food/in 0.100000 1.000 1.000 

3600224000 36 Milk, water 0.100000 1.000 1.000 

3600224001 36 Milk, water-babyfood/infant form 0.100000 1.000 1.000 

3600225001 36 Milk, sugar (lactose)-baby food/ 0.100000 1.000 1.000 

3800221000 38 Meat, game 0.100000 1.000 1.000 

3900312000 39 Rabbit, meat 0.100000 1.000 1.000 

4000093000 40 Chicken, meat 0.050000 1.000 1.000 

4000093001 40 Chicken, meat-babyfood 0.050000 1.000 1.000 

4000094000 40 Chicken, liver 0.200000 1.000 1.000 

4000095000 40 Chicken, meat byproducts 0.200000 1.000 1.000 

4000095001 40 Chicken, meat byproducts-babyfoo 0.200000 1.000 1.000 

4000096000 40 Chicken, fat 0.200000 1.000 1.000 

4000096001 40 Chicken, fat-babyfood 0.200000 1.000 1.000 

4000097000 40 Chicken, skin 0.200000 1.000 1.000 

4000097001 40 Chicken, skin-babyfood 0.200000 1.000 1.000 

5000382000 50 Turkey, meat 0.050000 1.000 1.000 

5000382001 50 Turkey, meat-babyfood 0.050000 1.000 1.000 

5000383000 50 Turkey, liver 0.200000 1.000 1.000 

5000383001 50 Turkey, liver-babyfood 0.200000 1.000 1.000 

5000384000 50 Turkey, meat byproducts 0.200000 1.000 1.000 

5000384001 50 Turkey, meat byproducts-babyfood 0.200000 1.000 1.000 

5000385000 50 Turkey, fat 0.200000 1.000 1.000 

5000385001 50 Turkey, fat-babyfood 0.200000 1.000 1.000 

5000386000 50 Turkey, skin 0.200000 1.000 1.000 

5000386001 50 Turkey, skin-babyfood 0.200000 1.000 1.000 

6000301000 60 Poultry, other, meat 0.050000 1.000 1.000 

6000302000 60 Poultry, other, liver 0.200000 1.000 1.000 

6000303000 60 Poultry, other, meat byproducts 0.200000 1.000 1.000 

6000304000 60 Poultry, other, fat 0.200000 1.000 1.000 

6000305000 60 Poultry, other, skin 0.200000 1.000 1.000 

7000145000 70 Egg, whole 1.000000 1.000 1.000 

7000145001 70 Egg, whole-babyfood 1.000000 1.000 1.000 

7000146000 70 Egg, white 1.000000 1.000 1.000 

7000146001 70 Egg, white (solids)-babyfood 1.000000 1.000 1.000 

7000147000 70 Egg, yolk 1.000000 1.000 1.000 

7000147001 70 Egg, yolk-babyfood 1.000000 1.000 1.000 

8000161000 80 Fish-shellfish, crustacean 8.000000 1.000 1.000 

8601000000 86A Water, direct, all sources 0.039870 1.000 1.000 

8602000000 86B Water, indirect, all sources 0.039870 1.000 1.000 

9500001000 O Acerola 2.000000 1.000 1.000 

9500016000 O Artichoke, globe 4.000000 1.000 1.000 

9500019000 O Asparagus 13.000000 1.000 1.000 

9500020000 O Avocado 4.000000 1.000 1.000 

9500023000 O Banana 4.000000 1.000 1.000 

9500023001 O Banana-babyfood 4.000000 1.000 1.000 

9500024000 O Banana, dried 4.000000 3.900 1.000 

9500024001 O Banana, dried-babyfood 4.000000 3.900 1.000 

9500073000 O Cactus 13.000000 1.000 1.000 

9500074000 O Canistel 4.000000 1.000 1.000 

9500089000 O Cherimoya 4.000000 1.000 1.000 

9500109000 O Cocoa bean, chocolate 1.500000 1.000 1.000 

9500110000 O Cocoa bean, powder 1.500000 1.000 1.000 

9500115000 O Coffee, roasted bean 0.400000 1.000 1.000 

9500116000 O Coffee, instant 2.000000 1.000 1.000 

9500151000 O Feijoa 4.000000 1.000 1.000 

9500153000 O Fig 4.000000 1.000 1.000 

9500154000 O Fig, dried 4.000000 1.000 1.000 

9500177000 O Grape, leaves 2.400000 1.000 1.000 

9500178000 O Grape, raisin 5.000000 1.000 1.000 

9500183000 O Guava 4.000000 1.000 1.000 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

Page 17 of 21

9500183001 O Guava-babyfood 4.000000 1.000 1.000 

9500188000 O Hop 90.000000 1.000 1.000 

9500209000 O Longan 4.000000 1.000 1.000 

9500211000 O Lychee 2.000000 1.000 1.000 

9500212000 O Lychee, dried 2.000000 1.850 1.000 

9500215000 O Mango 4.000000 1.000 1.000 

9500215001 O Mango-babyfood 4.000000 1.000 1.000 

9500216000 O Mango, dried 4.000000 1.000 1.000 

9500217000 O Mango, juice 4.000000 1.000 1.000 

9500217001 O Mango, juice-babyfood 4.000000 1.000 1.000 

9500235000 O Olive 4.000000 1.000 1.000 

9500236000 O Olive, oil 40.000000 1.000 1.000 

9500245000 O Papaya 2.000000 1.000 1.000 

9500245001 O Papaya-babyfood 2.000000 1.000 1.000 

9500246000 O Papaya, dried 2.000000 1.800 1.000 

9500247000 O Papaya, juice 2.000000 1.500 1.000 

9500252000 O Passionfruit 2.000000 1.000 1.000 

9500252001 O Passionfruit-babyfood 2.000000 1.000 1.000 

9500253000 O Passionfruit, juice 2.000000 1.000 1.000 

9500253001 O Passionfruit, juice-babyfood 2.000000 1.000 1.000 

9500275000 O Peppermint 9.000000 1.000 1.000 

9500276000 O Peppermint, oil 9.000000 1.000 1.000 

9500277000 O Persimmon 4.000000 1.000 1.000 

9500279000 O Pineapple 1.500000 1.000 1.000 

9500279001 O Pineapple-babyfood 1.500000 1.000 1.000 

9500280000 O Pineapple, dried 1.500000 5.000 1.000 

9500281000 O Pineapple, juice 1.500000 1.700 1.000 

9500281001 O Pineapple, juice-babyfood 1.500000 1.700 1.000 

9500283000 O Plantain 4.000000 1.000 1.000 

9500284000 O Plantain, dried 4.000000 3.900 1.000 

9500289000 O Pomegranate 4.000000 1.000 1.000 

9500333000 O Sapote, Mamey 4.000000 1.000 1.000 

9500346000 O Soursop 4.000000 1.000 1.000 

9500351000 O Spanish lime 4.000000 1.000 1.000 

9500352000 O Spearmint 9.000000 1.000 1.000 

9500353000 O Spearmint, oil 9.000000 1.000 1.000 

9500358000 O Starfruit 4.000000 1.000 1.000 

9500361000 O Sugar apple 4.000000 1.000 1.000 

9500362000 O Sugarcane, sugar 14.000000 1.000 1.000 

9500362001 O Sugarcane, sugar-babyfood 14.000000 1.000 1.000 

9500363000 O Sugarcane, molasses 420.000000 1.000 1.000 

9500363001 O Sugarcane, molasses-babyfood 420.000000 1.000 1.000 

9500372000 O Tea, dried 50.000000 1.000 1.000 

9500373000 O Tea, instant 50.000000 1.000 1.000 
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

Page 18 of 21

Attachment 2: Chronic Food Plus Water Results

U.S. EPA Ver. 3.16, 03-08-d

DEEM-FCID Chronic analysis for CHLORANTRANILIPROLE NHANES 2003-2008 2-day

Residue file name: C:\Documents and Settings\krury\My Documents\My Work 

Files\Chlorantraniliprole\DEEM Files\CHLORANTRANILIPROLECHRONIC cereal grains pome fruit 

stone fruit 42413.R08

 Adjustment factor #2 NOT used.

Analysis Date 04-24-2013/12:54:08 Residue file dated: 04-24-2013/12:50:37

Reference dose (RfD, Chronic) = 1.58 mg/kg bw/day

COMMENT 1: Only a chronic endpoint; there is no acute endpoint

===============================================================================

 Total exposure by population subgroup

-------------------------------------------------------------------------------

 Total Exposure

 -----------------------------------

 Population mg/kg Percent of 

 Subgroup body wt/day Rfd 

-------------------------------------- ------------- ----------------

Total US Population 0.032474 2.1%

Hispanic 0.035645 2.3%

Non-Hisp-White 0.031945 2.0%

Non-Hisp-Black 0.030713 1.9%

Non-Hisp-Other 0.035478 2.2%

Nursing Infants 0.031317 2.0%

Non-Nursing Infants 0.060654 3.8%

Female 13+ PREG 0.028954 1.8%

Children 1-6 0.082272 5.2%

Children 7-12 0.038983 2.5%

Male 13-19 0.024883 1.6%

Female 13-19/NP 0.023964 1.5%

Male 20+ 0.027083 1.7%

Female 20+/NP 0.026436 1.7%

Seniors 55+ 0.026317 1.7%

All Infants 0.051597 3.3%

Female 13-50 0.025757 1.6%

Children 1-2 0.099596 6.3%

Children 3-5 0.076426 4.8%

Children 6-12 0.042431 2.7%

Youth 13-19 0.024386 1.5%

Adults 20-49 0.026971 1.7%

Adults 50-99 0.026545 1.7%

Female 13-49 0.025763 1.6%

-------------------------------------------------------------------------------
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

Page 19 of 21

Attachment 3: Structures of Chlorantraniliprole and Possible Metabolites

Structures of Chlorantraniliprole and Possible Metabolites.

Chemical Name; Company Code Structure

3-Bromo-N-[4-chloro-2-methyl-6-

[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-

pyridinyl)-1H-pyrazole-5-carboxamide

Chlorantraniliprole

DPX-E2Y45

3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-

carboxylic acid

IN-DBC80

2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-

6-chloro-3, 8-dimethyl-4(3H)-quinazolinone

IN-EQW78

5-Bromo-N-methyl-1H-pyrazole-3-carboxamide

IN-F6L99

N-[2-(Aminocarbonyl)-4-chloro-6-methylphenyl]-3-

bromo-1-(3-chloro-2-pyridinyl)1H-pyrazole-5-

carboxamide

IN-F9N04

2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-

6-chloro-8-methyl-4(3H)-quinazolinone

IN-GAZ70

N N N

NH

O

Cl

Br

HN

O

Cl

N

N N

O

Cl

Br

OH

N

N

N

N N

Br

O

Cl

Cl

N

H

HN

O

N

Br

N

N N

NH

O

Cl

Br

O

Cl

NH2

N

NH

N

N N

Br

O

Cl

Cl
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

Page 20 of 21

Structures of Chlorantraniliprole and Possible Metabolites.

Chemical Name; Company Code Structure

3-Bromo-N-[4-chloro-2-

[[(hydroxymethyl)amino]carbonyl]-6-methylphenyl]-1-

(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide

IN-H2H20

N-[2-Aminocarbonyl]-4-chloro-6-

(hydroxymethyl)phenyl]-3-bromo-1-(3-chloro-2-

pyridinyl)-1H-pyrazole-5-carboxamide

IN-HXH40

3-Bromo-N-[4-chloro-2-(hydroxymethyl)-6-

[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-

pyridinyl)-1H-pyrazole-5-carboxamide

IN-HXH44

2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-

6-chloro-8-(hydroxymethyl)-4(3H)-quinazolinone

IN-K7H29

3-Bromo-N-[4-chloro-2-(hydroxymethyl)-6-

[[(hydroxymethyl)amino)carbonyl]phenyl]-1-(3-

chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide

IN-K9T00

N

N N

NH

O

Cl

Br

HN

O

Cl

OH

N

N N

NH

O

Cl

Br

NH2

O

Cl

HO

N

N N

NH

O

Cl

Br

HN

O

Cl

HO

N

NH

N

N N

Br

O

Cl

Cl

HO

N N N

NH

O

Cl

Br

HN

O

Cl

HO

OH
Chlorantraniliprole Dietary Exposure and Risk Assessment DP Number: D411997

Page 21 of 21

Structures of Chlorantraniliprole and Possible Metabolites.

Chemical Name; Company Code Structure

6-Chloro-1, 2, 3, 4-tetrahydro-2, 4-dioxo-8-

quinazolinecarboxylic acid

IN-K9X71

2-[[[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-

yl]carbonyl]amino]-5-chloro-3-

[(methylamino)carbonyl]benzoic acid

IN-KAA24

2-Amino-5-chloro-3-[(methylamino)carbonyl]benzoic 

acid

IN-L8F56

IN-E5F18 Not provided

N

H

NH

O

O

Cl

HO O

N N N

NH

O

Cl

Br

HN

O

Cl

HO

O

O

Cl

HO O

N

NH2