**Exhibit
      31.1**




CERTIFICATION
      PURSUANT TO


SECTION
      302 OF THE SARBANES-OXLEY ACT OF 2002





I,
      Liu
      Yan-Qing, President, Chief Executive Officer and Director (principal executive
      officer) of China Sky One Medical, Inc. (the “Registrant”), certify
      that:





1.  I
      have
      reviewed this Annual Report on Form 10-KSB of the Registrant for the fiscal
      year
      ended December 31, 2007, as filed with the Securities and Exchange Commission
      on
      the date hereof (the “Annual Report”);





2.  Based
      on
      my knowledge, this Annual Report does not contain any untrue statement of a
      material fact or omit to state a material fact necessary to make the statements
      made, in light of the circumstances under which such statements were made,
      not
      misleading with respect to the period covered by this Annual
      Report;





3.  Based
      on
      my knowledge, the financial statements, and other financial information included
      in this Annual Report, fairly present in all material respects the financial
      condition, results of operations and cash flows of the Registrant as of, and
      for, the periods presented in this Annual Report;





4.  The
      Registrant’s other certifying officer and I are responsible for establishing and
      maintaining disclosure controls and procedures (as defined in Exchange Act
      Rules
      13a-15(e) and 15d-15(e)) and internal control over financial reporting (as
      defined in Exchange Act Rules 13a-15(f) and 15d-15(f) for the Registrant and
      have:





(a)  Designed
      such disclosure controls and procedures, or caused such disclosure controls
      and
      procedures to be designed under our supervision, to ensure that material
      information relating to the Registrant, including its consolidated subsidiaries,
      is made known to us by others within those entities, particularly during the
      period in which this Annual Report is being prepared;





(b)  Designed
      such internal control over financial reporting, or caused such internal control
      over financial reporting to be designed under our supervision, to provide
      reasonable assurance regarding the reliability of financial reporting and the
      preparation of financial statements for external purposes in accordance with
      generally accepted accounting principles;





(c)  Evaluated
      the effectiveness of the Registrant’s disclosure controls and procedures and
      presented in this report our conclusions about the effectiveness of the
      disclosure controls and procedures, as of the end of the period covered by
      this
      Annual Report based on such evaluation (the “Evaluation Date”); and





(d)  Disclosed
      in this Annual Report any change in the Registrant’s internal control over
      financial reporting that occurred during the Registrant’s most recent fiscal
      quarter (the Registrant’s fourth fiscal quarter in the case of an annual report)
      that has materially affected, or is reasonably likely to materially affect,
      the
      Registrant’s internal control over financial reporting; and





5.  The
      Registrant’s other certifying officer and I have disclosed, based on our most
      recent evaluation of internal control over financial reporting, to the
      Registrant’s auditors and the audit committee of Registrant’s board of directors
      (or persons performing the equivalent functions):





(a)  All
      significant deficiencies and material weaknesses in the design or operation
      of
      internal control over financial reporting which are reasonably likely to
      adversely affect the Registrant’s ability to record, process, summarize and
      report financial information; and




(b)  Any
      fraud, whether or not material, that involves management or other employees
      who
      have a significant role in the Registrant’s internal control over financial
      reporting.





Dated:
              March 31, 2008
            Signature:
            /s/Liu Yan-QingLiu
                Yan-Qing
              President
                and Chief Executive Officer
              (principal
                executive officer)