* Agenda times are app roximate and subject to change depending upon the discussion. **US ENVIRONMENTAL PROTECTION AGENCY** 

### HUMAN STUDIES REVIEW BOARD **NOVMEBER 201**  **2 PUBLIC MEETING**  **AGENDA Environmental Protection Agency Conference Center**  Lobb y Level - One Potomac Yard (South Bldg.) 2777 S. Cry stal Drive, Arlington, VA 22202 Thursday , November 1 , 201 2 **HSRB WEB SITE http://www.epa.gov/osa/hsrb/ Docket Telephone: (202) 566 1752**  **Docket Number: EPA**

**– HQ** **– ORD** **– 2012**  **– 0**  **718 1:00 PM**  ***** **Convene Public Meeting**  **–** Jim Downing , Designated Federal Officer, EPA

Human Studies Review Board, Office of the Science Advisor **Introduction of Board Members**

–Rebecca Parkin , Ph.D. , MPH , HSRB Chair **Welcome** - Glenn Paulson, Ph.D., Science Advisor, EPA **Opening Remarks –**  Steven Bradbury , Ph.D., Director, Office of Pesticide Programs (OPP), Office of Chemical Safety and Pollution Prevention, EPA **Follow -**  **up on Previous HSRB Recommendations –**  Mr. William Jordan, OPP, Office of Chemical Safety and Pollution P revention, EPA **Session 1: A completed study report from the Antimicrobial Exposure Assessment Task** 

**Force II (AEATF) in which the dermal and inhalation exposure of professional janitorial workers was monitored as they poured liquid antimicrobial pesticide**  **products from conventional or reduced -**  **splash containers into different sizes and types of source containers.**  EPA seeks the advice of the HSRB on the scientific soundness of this completed research and on its appropriateness for use in estimating exposure that results from pouring liquid antimicrobial pesticide products. EPA also seeks the advice of the HSRB on whether available information supports a determination that the study was conducted in substantial compliance with subparts K and L of 40 CFR Part 26 . **1:4 0**  **P M**  **EPA Science Review**  **–** Mr. Tim L eighton , (OPP, EPA) **2:15 P**  **M Board Questions of Clarification** 

– Rebecca Parkin , Ph.D. , MPH (HSRB Chair),

EPA, Principal Investigator/Sponsor **2:45 P**  **M EPA Ethics**  **Assessment -**  Ms. Kelly Sherman (OPP, EPA) **3 :**  **15 P**  **M Board Questions of Clarification** 

– Rebecca Parkin , Ph.D. , MPH (HSRB Chair),

EPA, Principal Investigator/Sponsor **3:45 PM Break**  **3 :**  **55 P**  **M Public Comments**  **4 :**  **05 PM**  **Board Discussion*** Agenda times are app roximate and subject to change depending upon the discussion.

Charge to the Board - Science:  Was the research reported in the Antimicrobial Exposure Assessment Task Force II (AEATF) completed study report faithful to the design and objectives of the protocol and governing documents of AEATF?  Has EPA adequatel y characterized, from a scientific perspective, the limitations on these data that should be considered when using the data in estimating the exposure of professional janitorial workers who pour liquid antimicrobial pesticide products from conventional or reduced - splash containers into different sizes and types of source containers ? Charge to the Board - Ethics:  Does available information support a determination that the study was conducted in substantial compliance with subparts K and L of 40 CFR Part 26? **5 :**  **0 0 PM**  ***** **Adjourn**