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Exhibit 31.1

CERTIFICATION PURSUANT TO SECTION 302 OF
		THE SARBANES-OXLEY ACT OF 2002

I, Raymond P. Warrell, Jr., M.D., certify
		that:

1.
			 I have reviewed this Quarterly
				  Report on Form 10-Q of Genta Incorporated (the registrant);


2.
			 Based on my knowledge, this report
				  does not contain any untrue statement of a material fact or omit to state a
				  material fact necessary to make the statements made, in light of the
				  circumstances under which such statements were made, not misleading with
				  respect to the period covered by this report;


3.
			 Based on my knowledge, the financial
				  statements, and other financial information included in this report, fairly
				  present in all material respects the financial condition, results of operations
				  and cash flows of the registrant as of, and for, the periods presented in this
				  report;


4.
			 The registrants other
				  certifying officer and I are responsible for establishing and maintaining
				  disclosure controls and procedures as defined in Exchange Act Rules 13a-15(e)
				  and 15d-15(e) and internal control over financial reporting as defined in
				  Exchange Act Rules 13a-15(f) and 15d-15(f) for the registrant and we
				  have:


a)
			 Designed such disclosure controls
				  and procedures, or caused such disclosure controls and procedures to be
				  designed under our supervision, to ensure that material information relating to
				  the registrant, including its consolidated subsidiaries, is made known to us by
				  others within those entities, particularly during the period in which this
				  report is being prepared;


b)
			 Designed such internal control over
				  financial reporting, or caused such internal control over financial reporting
				  to be designed under our supervision, to provide reasonable assurance regarding
				  the reliability of financial reporting and the preparation of financial
				  statements for external purposes in accordance with generally accepted
				  accounting principles;


c)
			 Evaluated the effectiveness of the
				  registrants disclosure controls and procedures and presented in this
				  report our conclusions about the effectiveness of the disclosure controls and
				  procedures, as of the end of the period covered by this report based on such
				  evaluation; and


d)
			 Disclosed in this report any change
				  in the registrants internal control over financial reporting that
				  occurred during the registrants most recent fiscal quarter that has
				  materially affected, or is reasonably likely to materially affect, the
				  registrants internal control over financial reporting; and


5.
			 The registrants other
				  certifying officer and I have disclosed, based on our most recent evaluation of
				  internal control over financial reporting, to the registrants auditors
				  and the audit committee of the registrants board of directors (or persons
				  performing the equivalent functions):


a)
			 All significant deficiencies and
				  material weaknesses in the design or operation of internal control over
				  financial reporting which are reasonably likely to adversely affect the
				  registrants ability to record, process, summarize and report financial
				  information; and


b)
			 Any fraud, whether or not material,
				  that involves management or other employees who have a significant role in the
				  registrants internal control over financial reporting.




Date:
			 August 7, 2007/s/ RAYMOND P. WARRELL, JR.,
				  M.D.Name:
			 Raymond P. Warrell, Jr., M.D.Title:
			 Chairman and Chief Executive
				  Officer














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