Exhibit 31.1

CERTIFICATION
PURSUANT TO SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

I,
Raymond P. Warrell, Jr., M.D., certify that:

|1. |  | I
have reviewed this Quarterly Report on Form 10-Q of Genta Incorporated (the registrant);
|-- |  | --------------------------------------------------------------------------------------------

|2. |  | Based
on my  knowledge,  this report does not contain any untrue  statement of a material  fact
or omit to state a  material fact necessary to make the statements  made, in light of the
circumstances  under which such  statements  were made, not misleading with respect to
the period covered by this report;
|-- |  | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|3. |  | Based
on my knowledge,  the financial statements,  and other financial information included in
this report, fairly  present in all material respects the financial  condition,  results
of operations and cash flows of the registrant  as of, and for, the periods presented in
this report;
|-- |  | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|4. |  | The
registrants  other  certifying  officer and I are responsible for  establishing
and maintaining  disclosure  controls and procedures (as defined in Exchange Act Rules
13a-15(e) and 15d-15(e)) for the registrant and we have:
|-- |  | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|a) |  | Designed
such  disclosure  controls and  procedures,  or caused such  disclosure  controls and
procedures  to be  designed  under  our  supervision,  to ensure  that  material
information  relating  to the  registrant,  including  its  consolidated  subsidiaries,
is  made  known  to  us by  others  within  those  entities,  particularly during the
period in which this report is being prepared;
|-- |  | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|b) |  | [Reserved]
|-- |  | ----------

|c) |  | Evaluated
the  effectiveness of the registrants  disclosure  controls and procedures and
presented in this report  our conclusions about the effectiveness of the disclosure
controls and procedures,  as of the end of the  period covered by this report based on
such evaluation; and
|-- |  | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|d) |  | Disclosed
in this report any change in the registrants  internal  control over financial
reporting that occurred  during the registrants most recent fiscal quarter that has
materially affected,  or is reasonably likely  to materially affect, the registrants
internal control over financial reporting; and
|-- |  | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|5. |  | The
registrants  other certifying  officer and I have disclosed,  based on our most
recent evaluation of internal  control over financial reporting,  to the registrants
auditors and the audit committee of the registrants board  of directors (or persons
performing the equivalent functions):
|-- |  | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|a) |  | All
significant  deficiencies  and  material  weaknesses  in the design or  operation  of
internal  control  over  financial  reporting which are reasonably likely to adversely
affect the registrants  ability to record,  process, summarize and report financial
information; and
|-- |  | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|b) |  | Any
fraud,  whether or not material,  that involves  management or other employees who have a
significant  role in  the registrants internal control over financial reporting.
|-- |  | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



|Date:                                   |  | May 10, 2004                       
|--------------------------------------- |  | -----------------------------------
|                                        |  |                                    
|/s/
      RAYMOND P. WARRELL, JR., M.D.
|Name:                                   |  | Raymond P. Warrell,
      Jr., M.D.
|Title:                                  |  | Chief Executive Officer            

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