|Exhibit 10.35



Dear Rich,


Your January 9, 2001 agreement (the
Original Agreement) with IMPATH Inc. (the Company) contained
certain provisions with regard to a change in control of the Company and severance. This
letter sets forth revised terms and is intended to modify the terms of the Original
Agreement.


The third paragraph of the Original
Agreement is amended and replaced in its entirety as follows:
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| | Your
employment will be at-will and either party can terminate the employment
relationship with or without cause, and at any time; provided, however that, (i) should
the Company terminate you for reasons other than gross negligence or willful misconduct,
or (ii) should you terminate your employment with the Company for (a) a reduction in your
base salary from the annualized rate in effect on the date hereof or as hereafter
increased or (b) a demotion in your position with the Company or change in your duties and
responsibilities inconsistent with your position, which reduction, demotion or change
shall not have been corrected by the Company within ten (10) days following notice thereof
by you to the Company then, in the case of (i) or (ii) above you would receive twelve (12)
months base pay as severance.
| | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

| | In
addition, if (i) a change in control occurs or (ii) your employment by the Company is
terminated prior to the date a change of control occurs, and it is reasonably demonstrated
that such termination (a) was at the request of a third party who has taken steps
reasonably calculated to effect a change of control, or (b) otherwise arose in connection
with or in anticipation of a change of control, then the Company shall pay to you, within
90 days after the date of the change of control, as a payment for services previously
rendered to the Company, a lump sum equal to one (1) times (x) your annual salary in
effect immediately prior to the date of the change of control, plus (y) 100% of the target
bonus or other cash incentive that you are eligible to earn in such year. Change in
control will have the meaning that it has for other executive officers of the Company.
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|To the extent that this letter is
inconsistent with any terms or provisions of the Original Agreement, the terms of this
letter shall govern.


If the terms of this letter are
consistent with your understanding of our agreement, please sign two copies and return one
to me.
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|                    | 
|------------------- | 
|Sincerely,          | 
|                    | 
|                    | 
|/s/ Richard Adelson | 
|December 30, 2002   | 

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