# I U C L I D D a t a s e t

Existing Chemical Substance ID: 68140–01–2 CAS No. 68140–01–2 EINECS NameAmides, coco, N–[3–(dimethylamino)propyl] EINECS No. 268–771–8 Molecular Formula <no data>

Dataset created by: EUROPEAN COMMISSION – European Chemicals Bureau This dossier is a compilation based on data reported by the European Chemicals Industry following ’Council Regulation (EEC) No. 793/93 on the Evaluation and Control of the Risks of Existing Substances’. All (non–confidential) information from the single datasets, submitted in the IUCLID/HEDSET format by individual companies, was integrated to create this document. The data have not undergone any evaluation by the European Commission.

Creation date: 19–FEB–2000

Number of Pages: 17 Chapters: all Edition: Year 2000 CD–ROM edition Flags: non–confidential

(C) 2000 EUROPEAN COMMISSION European Chemicals Bureaudate: 19–FEB–2000 1. General Information Substance ID: 68140–01–2

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### 1.0.1 OECD and Company Information Name: Albright & Wilson UK Limited Street: 210–222 Hagley Road West Town: B68 0NN Oldbury Country: United Kingdom Phone: +44 121 429 4942 Telefax: +44 121 420 5151 Telex: 336291

Name: Clariant GmbH Town: 65926 Frankfurt am Main Country: Germany

Name: Clariant UK Ltd. Street: Calverley lane Town: 25184RP Horsforth, Leeds Country: United Kingdom

Name: Croda Universal Ltd Street: Cowick Hall, Snaith Town: DN14 9AA Goole, North Humberside Country: United Kingdom Phone: 0405 860551 Telefax: 0405 860205 Telex: 57601 Cedex: DN14 9AA

Name: F.LLI RICCI S.R.L. Street: A. COLOMBO 128 Town: 20055 GORLA MINORE (VA) Country: Italy Phone: 0331–365385 Telefax: 0331–365759

Name: Goldschmidt Italia S.r.l. Street: Falconera, 7 Town: 26025 Pandino Country: Italy Phone: 0373–9751 Telefax: 0373–975260

Name: Henkel KGaA Street: Henkelstr. 67 Town: 40589 Duesseldorf Country: Germany

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Name: Huels AG Street: Postfach Town: D–45764 Marl Country: Germany

Name: KAO Corporation S.A. Street: Puig dels Tudons 10 Town: 08210 Barbera del Valles Country: Spain

Name: STEPAN EUROPE Street: Chemin Jongkind / BP127 Town: 38340 Voreppe Country: France 

### 1.0.2 Location of Production Site

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### 1.0.3 Identity of Recipients

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### 1.1 General Substance Information Substance type: organic Physical status: liquid Substance type: organic Physical status: solid Substance type: organic Physical status: 

### 1.1.1 Spectra

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### 1.2 Synonyms Alkamide CAP Source: Henkel KGaA Duesseldorf Amida CHF (KAO) Source: KAO Corporation S.A. Barbera del Valles Amides, coco, N–[3–(dimethylamino)propyl] Source: Henkel KGaA Duesseldorf Amindes, coco, N–[3–(dimethylamino)propyl] Source: Hoechst AG Frankfurt/Main Clariant GmbH Frankfurt am Main
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______________________________________________________________________________ Aminoamid Source: Henkel KGaA Duesseldorf Cocamidopropyl dimethylamine Source: KAO Corporation S.A. Barbera del Valles Goldschmidt Italia S.r.l. Pandino Cocamidopropyl Dimethylamine Source: Croda Universal Ltd Goole, North Humberside COCAMIDOPROPYL DIMETHYLAMINE Source: Henkel KGaA Duesseldorf COCAMIDOPROPYL DIMETHYLAMINE (INCI) Source: Henkel KGaA Duesseldorf Cocamidopropyldimethylamine Source: Henkel KGaA Duesseldorf Coco amides, N–[3–(dimethylamino)propyl] Source: Henkel KGaA Duesseldorf Coco amides, N–[‘3–(dimethylamino)propyl] Source: KAO Corporation S.A. Barbera del Valles Coconut fatty acid, dimethylaminopropylamid Source: Henkel KGaA Duesseldorf Coconut fatty acid, dimethylaminopropylamide Source: Henkel KGaA Duesseldorf Coconut fatty acid, dimethylaminopropylamide (ALTSTOFF) Source: Henkel KGaA Duesseldorf Dimethylaminopropylkokosfettsäureamid Source: Henkel KGaA Duesseldorf MARLAMID JB Source: Huels AG Marl Mazeen CA Source: Henkel KGaA Duesseldorf N,N–Dimethyl–N(C8–18–kokosacylamidopropyl)amin Source: Henkel KGaA Duesseldorf N–[3–(Dimethylamino)propyl] coco amides Source: Henkel KGaA Duesseldorf N–[‘3–(Dimethylamino)propyl] coco amides Source: KAO Corporation S.A. Barbera del Valles 

### 1.3 Impurities

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– 3/17 –date: 19–FEB–2000 1. General Information Substance ID: 68140–01–2

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### 1.4 Additives

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### 1.5 Quantity Quantity 10 000 – 50 000 tonnes 

### 1.6.1 Labelling

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### 1.6.2 Classification

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### 1.7 Use Pattern Type: type Category: Non dispersive use Type: type Category: Use in closed system Type: type Category: Wide dispersive use Type: type Category: Type: industrial Category: Chemical industry: used in synthesis Type: industrial Category: Paints, lacquers and varnishes industry Type: industrial Category: Personal and domestic use Type: industrial Category: Textile processing industry Type: use Category: Cosmetics Type: use Category: Intermediates Type: use Category: Surface–active agents Type: use Category: other: Pigmentpräparation

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### 1.7.1 Technology Production/Use

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### 1.8 Occupational Exposure Limit Values

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### 1.9 Source of Exposure Remark: Manufactured at one site only Source: Croda Universal Ltd Goole, North Humberside 

### 1.10.1 Recommendations/Precautionary Measures

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### 1.10.2 Emergency Measures

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### 1.11 Packaging

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### 1.12 Possib. of Rendering Subst. Harmless

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### 1.13 Statements Concerning Waste

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### 1.14.1 Water Pollution Classified by: other: Henkel Labelled by: Class of danger: 2 (water polluting) Remark: Self classification by Henkel KGaA Source: Transfer program Henkel KGaA Duesseldorf Classified by: other: Hoechst AG Labelled by: other: Selbsteinstufung Class of danger: 2 (water polluting) Source: Hoechst AG Frankfurt/Main Clariant GmbH Frankfurt am Main (1) 

### 1.14.2 Major Accident Hazards

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### 1.14.3 Air Pollution

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### 1.15 Additional Remarks

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### 1.16 Last Literature Search

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### 1.17 Reviews

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### 1.18 Listings e.g. Chemical Inventories

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– 6/17 –date: 19–FEB–2000 2. Physico–chemical Data Substance ID: 68140–01–2

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### 2.1 Melting Point Value: Source: F.LLI RICCI S.R.L. GORLA MINORE (VA) 

### 2.2 Boiling Point Value: > 200 degree C Source: F.LLI RICCI S.R.L. GORLA MINORE (VA) 

### 2.3 Density Type: density Value: 1.06 g/cm3 at 20 degree C Source: Henkel KGaA Duesseldorf (2) 

### 2.3.1 Granulometry

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### 2.4 Vapour Pressure

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### 2.5 Partition Coefficient

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### 2.6.1 Water Solubility Value: < 10 g/l at 20 degree C pH: ca. 9 at 5 g/l and 20 degree C Source: F.LLI RICCI S.R.L. GORLA MINORE (VA) Value: at 20 degree C Qualitative: of high solubility Source: Henkel KGaA Duesseldorf (2) 

### 2.6.2 Surface Tension

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### 2.7 Flash Point Value: > 100 degree C Type: Method: Year: Source: Henkel KGaA Duesseldorf (2)
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### 2.8 Auto Flammability

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### 2.9 Flammability

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### 2.10 Explosive Properties Result: not explosive Source: F.LLI RICCI S.R.L. GORLA MINORE (VA) 

### 2.11 Oxidizing Properties Result: no oxidizing properties Source: F.LLI RICCI S.R.L. GORLA MINORE (VA) 

### 2.12 Additional Remarks

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– 8/17 –date: 19–FEB–2000 3. Environmental Fate and Pathways Substance ID: 68140–01–2

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### 3.1.1 Photodegradation

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### 3.1.2 Stability in Water

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### 3.1.3 Stability in Soil

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### 3.2 Monitoring Data (Environment)

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### 3.3.1 Transport between Environmental Compartments

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### 3.3.2 Distribution

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### 3.4 Mode of Degradation in Actual Use

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### 3.5 Biodegradation Type: aerobic Inoculum: other: sewage treatment plant effluent/biological stage Concentration: 5 mg/l related to DOC (Dissolved Organic Carbon) Degradation: 26 – 37 % after 28 day Method: Directive 84/449/EEC, C.3 "Biotic degradation – modified OECD screening test" Year: GLP: Test substance: as prescribed by 1.1 – 1.4 Method: EG–RiLi 84/449 Anh.V C4–B Remark: stark schwankende, z.T. negative Zwischenwerte Source: Henkel KGaA Duesseldorf Test condition: #1: 5 mg/l referring to DOC: 26% with parameter % DOC–Abnahme #2: 10 mg/l referring to DOC: 37% with parameter % DOC–Abnahme (3) (4)

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______________________________________________________________________________ Type: aerobic Inoculum: other: sewage treatment plant effluent/biological stage Concentration: 2 mg/l Degradation: 86 – 81 % after 30 day Result: readily biodegradable Method: Directive 84/449/EEC, C.6 "Biotic degradation – closed bottle test" Year: GLP: Test substance: as prescribed by 1.1 – 1.4 Method: EG–RiLi 84/449 Anh.V C4–E Remark: erhebliche Trübung der Prüfmusterstammlösung. Source: Henkel KGaA Duesseldorf Test condition: #1: 2 mg/l referring to Active Substance: 86% with parameter % BSB/CSB #2: 5 mg/l referring to Active Substance: 81% with parameter % BSB/CSB (5) (6) Type: aerobic Inoculum: other: sewage treatment plant effluent/biological stage Degradation: 65 % after 28 day Result: other: biodegradable Method: OECD Guide–line 301 D "Ready Biodegradability: Closed Bottle Test" Year: 1991 GLP: Test substance: as prescribed by 1.1 – 1.4 Source: Henkel KGaA Duesseldorf (7) 

### 3.6 BOD5, COD or BOD5/COD Ratio

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### 3.7 Bioaccumulation

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### 3.8 Additional Remarks

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– 10/17 –date: 19–FEB–2000 4. Ecotoxicity Substance ID: 68140–01–2

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### AQUATIC ORGANISMS 4.1 Acute/Prolonged Toxicity to Fish

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### 4.2 Acute Toxicity to Aquatic Invertebrates Species: Daphnia magna (Crustacea) Exposure period: 24 hour(s) Unit:mg/lAnalytical monitoring: EC0: = .4 EC50: = .63 EC100: = 1 Method: OECD Guide–line 202, part 1 "Daphnia sp., Acute Immobilisation Test" Year: 1991 GLP: Test substance: as prescribed by 1.1 – 1.4 Result: related to test substance Source: Henkel KGaA Duesseldorf Test substance: Active Matter = 100% (7) Species: Daphnia magna (Crustacea) Exposure period: 48 hour(s) Unit:mg/lAnalytical monitoring: EC0: = .2 EC50: = .4 EC100: = .8 Method: OECD Guide–line 202, part 1 "Daphnia sp., Acute Immobilisation Test" Year: 1991 GLP: Test substance: as prescribed by 1.1 – 1.4 Result: related to test substance Source: Henkel KGaA Duesseldorf Test substance: Active Matter = 100% (7) 

### 4.3 Toxicity to Aquatic Plants e.g. Algae

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### 4.4 Toxicity to Microorganisms e.g. Bacteria Type: Species: Pseudomonas putida (Bacteria) Exposure period: 16 hour(s) Unit:mg/lAnalytical monitoring: EC10: = 280 EC50: = 570 Method: other: DIN 38 412/8, Zellvermehrungshemmtest Year: 1991 GLP: Test substance: as prescribed by 1.1 – 1.4 Result: related to test substance Source: Henkel KGaA Duesseldorf Test substance: Active Matter = 100% (7) 

### 4.5 Chronic Toxicity to Aquatic Organisms 4.5.1 Chronic Toxicity to Fish

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### 4.5.2 Chronic Toxicity to Aquatic Invertebrates

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### TERRESTRIAL ORGANISMS 4.6.1 Toxicity to Soil Dwelling Organisms

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### 4.6.2 Toxicity to Terrestrial Plants

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### 4.6.3 Toxicity to other Non–Mamm. Terrestrial Species

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### 4.7 Biological Effects Monitoring

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### 4.8 Biotransformation and Kinetics

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### 4.9 Additional Remarks

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– 12/17 –date: 19–FEB–2000 5. Toxicity Substance ID: 68140–01–2

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### 5.1 Acute Toxicity 5.1.1 Acute Oral Toxicity Type: LD50 Species: rat Sex: Number of Animals: Vehicle: Value: > 2000 mg/kg bw Method: Directive 84/449/EEC, B.1 "Acute toxicity (oral)" Year: GLP: no data Test substance: as prescribed by 1.1 – 1.4 Source: Henkel KGaA Duesseldorf (8) Type: LD50 Species: rat Sex: Number of Animals: Vehicle: Value: = 200 – 2000 mg/kg bw Method: Directive 84/449/EEC, B.1 "Acute toxicity (oral)" Year: GLP: no data Test substance: as prescribed by 1.1 – 1.4 Source: Henkel KGaA Duesseldorf (8) 

### 5.1.2 Acute Inhalation Toxicity

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### 5.1.3 Acute Dermal Toxicity

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### 5.1.4 Acute Toxicity, other Routes

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### 5.2 Corrosiveness and Irritation

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### 5.2.1 Skin Irritation Species: rabbit Concentration: Exposure: Exposure Time: Number of Animals: PDII: Result: corrosive EC classificat.: Method: OECD Guide–line 404 "Acute Dermal Irritation/Corrosion" Year: GLP: no data Test substance: as prescribed by 1.1 – 1.4 Source: Henkel KGaA Duesseldorf (9) Species: other: hairless mouse Concentration: Exposure: Exposure Time: Number of Animals: PDII: Result: irritating EC classificat.: Method: Year: GLP: no data Test substance: as prescribed by 1.1 – 1.4 Remark: The substance was applied once. Source: Henkel KGaA Duesseldorf (9) Species: other: hairless mouse Concentration: Exposure: Exposure Time: Number of Animals: PDII: Result:moderately irritating EC classificat.: Method: Year: GLP: no data Test substance: as prescribed by 1.1 – 1.4 Remark: The substance was applied once daily to the same area of skin and gently massaged into it. Source: Henkel KGaA Duesseldorf (9)

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### 5.2.2 Eye Irritation Species: rabbit Concentration: Dose: Exposure Time: Comment: Number of Animals: Result: irritating EC classificat.: Method: OECD Guide–line 405 "Acute Eye Irritation/Corrosion" Year: GLP: no data Test substance: as prescribed by 1.1 – 1.4 Source: Henkel KGaA Duesseldorf (9) 

### 5.3 Sensitization

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### 5.4 Repeated Dose Toxicity

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### 5.5 Genetic Toxicity ’in Vitro’

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### 5.6 Genetic Toxicity ’in Vivo’

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### 5.7 Carcinogenicity

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### 5.8 Toxicity to Reproduction

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### 5.9 Developmental Toxicity/Teratogenicity

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### 5.10 Other Relevant Information

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### 5.11 Experience with Human Exposure

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– 15/17 –date: 19–FEB–2000 6. References Substance ID: 68140–01–2

______________________________________________________________________________ (1) Hoechst AG (1995): EG–Sicherheitsdatenblatt Hoe S 3267–3 (19.12.95) (2) HENKEL KGaA, SDS, 4/1998, ’Dehyton K Vorstufe’, DED 00085570 (3) Henkel KGaA, unpublished data, File 13, Page/Assay 449 (4) Henkel KGaA, unpublished data, Protocol 21, Page/Assay 449 (5) Henkel KGaA, unpublished data, File 61, Page/Assay 744 (6) Henkel KGaA, unpublished data, Protocol 32, Page/Assay 744 (7) Henkel KGaA, unpublished data, Archive–No. R 9601945 (External Report, Inst. Fresenius, 09/1991) (8) Henkel KGaA, unpublished data, Archive–No. TBD 850340 (9) Henkel KGaA, unpublished data, Archive–No. TBD 850317

– 16/17 –date: 19–FEB–2000 7. Risk Assessment Substance ID: 68140–01–2

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### 7.1 Risk Assessment

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– 17/17 –