Exhibit 21

Pharmaceutical Product Development, Inc., and Subsidiaries

Subsidiaries

The subsidiaries of Pharmaceutical Product Development, Inc., as of February 18, 2010, are
as follows:



|    |  |                                                           |  |                                             
|--- |  | --------------------------------------------------------- |  | --------------------------------------------
|    |  | Name of Subsidiary                                        |  | Jurisdiction of IncorporationOr Organized
in
|1.  |  | Applied Bioscience International, LLC                     |  | Delaware                                    
|2.  |  | PPD Global Central Labs, LLC                              |  | Kentucky                                    
|3.  |  | PPD Preclinical, LLC (Formerly PRC, LLC)                  |  | North Carolina                              
|4.  |  | PPD Aeronautics, LLC                                      |  | North Carolina                              
|5.  |  | PPD Virtual, Inc.                                         |  | North Carolina                              
|6.  |  | APBI Finance Corporation                                  |  | Delaware                                    
|7.  |  | APBI Holdings, LLC                                        |  | North Carolina                              
|8.  |  | Development Partners, LLC                                 |  | Delaware                                    
|9.  |  | PPD GP, LLC                                               |  | Delaware                                    
|10. |  | PPD Holdings, LLC                                         |  | Delaware                                    
|11. |  | PPD UK Holdings Ltd                                       |  | United Kingdom                              
|12. |  | Genupro, Inc.                                             |  | North Carolina                              
|13. |  | PPD Development, LP                                       |  | Texas                                       
|14. |  | ATP, LLC                                                  |  | North Carolina                              
|15. |  | Pharmaco Investments, Inc.                                |  | Delaware                                    
|16. |  | PPD International Holdings, Inc.                          |  | Delaware                                    
|17. |  | PPD France SNC                                            |  | France                                      
|18. |  | PPD Scandinavia AB                                        |  | Sweden                                      
|19. |  | Pharmaceutical Product Development Spain SL               |  | Spain                                       
|20. |  | PPD do Brasil-Suporte a Pesquisa Clinica Ltda.            |  | Brazil                                      
|21. |  | PPD Argentina, S.A.                                       |  | Argentina                                   
|22. |  | PPD International Holdings, Inc. y Compania Limitada      |  | Chile                                       
|23. |  | Pharmaceutical Product Development South Africa (Pty) Ltd |  | South Africa                                
|24. |  | PPD Canada, Ltd.                                          |  | Canada                                      
|25. |  | PPD Australia Pty Ltd                                     |  | Australia                                   
|26. |  | PPD International Holdings GmbH                           |  | Germany                                     
|27. |  | PPD Germany GmbH                                          |  | Germany                                     
|28. |  | PPD Poland Sp. Z o.o.                                     |  | Poland                                      
|29. |  | PPD Czech Republic s.r.o.                                 |  | Czech Republic                              
|30. |  | PPD Germany GmbH & Co KG                                  |  | Germany                                     
|31. |  | PPD Hungary Research & Development Limited                |  | Hungary                                     
|32. |  | PPD Italy S.r.l.                                          |  | Italy                                       
|33. |  | PPD Mexico, S.A. de C.V.                                  |  | Mexico                                      
|34. |  | PPD Development (Thailand) Co., Ltd                       |  | Thailand                                    
|35. |  | PPD Japan K.K.                                            |  | Japan                                       
|36. |  | PPD Global, Ltd                                           |  | United Kingdom                              
|37. |  | Clinical Technology Centre (International) Ltd            |  | United Kingdom                              
|38. |  | Cambridge Applied Nutrition Toxicology & Biosciences Ltd  |  | United Kingdom                              
|39. |  | Clinical Science Research International Ltd               |  | United Kingdom                              
|40. |  | Leicester Clinical Research Centre Ltd                    |  | United Kingdom                              
|41. |  | Chelmsford Clinical Trials Unit Ltd                       |  | United Kingdom                              
|42. |  | Gabbay Ltd                                                |  | United Kingdom                              
|43. |  | Data Analysis & Research (DAR) Ltd                        |  | Scotland                                    



1



---

|    |  |                                                                              |  |                
|--- |  | ---------------------------------------------------------------------------- |  | ---------------
|44. |  | PPD Global Central Labs BVBA                                                 |  | Belgium        
|45. |  | PPD Development (S) Pte Limited                                              |  | Singapore      
|46. |  | PPD Development (HK) Limited                                                 |  | Hong Kong      
|47. |  | PPD (Netherlands) BV                                                         |  | Netherlands    
|48. |  | PPD Pharmaceutical Development India Private Limited                         |  | India          
|49. |  | River Ventures, LLC                                                          |  | North Carolina 
|50. |  | PPD Slovak Republic s.r.o.                                                   |  | Slovak Republic
|51. |  | PPD Peru S.A.C.                                                              |  | Peru           
|52. |  | PPD Vaccines and Biologics, LLC                                              |  | Pennsylvania   
|53. |  | PPD Pharmaceutical Development (Beijing) Co., Ltd                            |  | China          
|54. |  | Greenbird Limited                                                            |  | Cyprus         
|55. |  | PPD Development Ireland Ltd                                                  |  | Ireland        
|56. |  | Limited Liability Company PPD Development (Smolensk)                         |  | Russia         
|57. |  | PPD Global Central Labs (S) Pte. Ltd.                                        |  | Singapore      
|58. |  | Limited Liability Company Contract Research Organization Innopharm  Ukraine |  | Ukraine        
|59. |  | PPD Dermatology, Inc.                                                        |  | Delaware       
|60. |  | PPD Therapeutics, Inc.                                                       |  | Delaware       
|61. |  | AbC.R.O., Inc.                                                               |  | Virginia       
|62. |  | PPD BULGARIA EOOD                                                            |  | Bulgaria       
|63. |  | BioDuro, LLC                                                                 |  | Delaware       
|64. |  | BioDuro (Mauritius)                                                          |  | Mauritius      
|65. |  | BIODURO (BAONUO) BEIJING TECHNOLOGY CO., LTD.                                |  | Beijing, China 
|66. |  | Excel Pharmastudies, Inc.                                                    |  | Cayman         
|67. |  | Excel (Beijing) Medical Technology Co., LTD.                                 |  | Beijing, China 
|68. |  | EXCEL PHARMASTUDIES TAIZHOU BIOMETRICS, INC.                                 |  | Taizhou, China 
|69. |  | EXCEL PHARMASTUDIES TAIZHOU VACCINE, INC.                                    |  | Taizhou, China 
|70. |  | Excel Pharmastudies (US), Inc.                                               |  | California     
|71. |  | PPD CT Investments LLP                                                       |  | United Kingdom 
|72. |  | ABC.R.O. Bulgaria EAD                                                        |  | Bulgaria       
|73. |  | ABC.R.O. Romania S.R.L.                                                      |  | Romania        
|74. |  | AbC.R.O. d.o.o.                                                              |  | Croatia        
|75. |  | AbC.R.O. Poland Sp. Z o.o.                                                   |  | Poland         
|76. |  | Limited Liability Company ABC.R.O.                                           |  | Russia         



2



---

Subsidiaries 1, 2, 3, 5, 52, 59, and 60 are wholly-owned subsidiaries of Pharmaceutical Product Development,
Inc.

Subsidiaries 9 and 10 are wholly-owned subsidiaries of Subsidiary 1.

Subsidiary 12 is a wholly-owned subsidiary of Subsidiary 5.

Subsidiary 13 is owned 99.9% by
Subsidiary 10 and 0.1% by Subsidiary 9.

Subsidiaries 4, 6, 7, 14, 15, 16, and 49 are wholly-owned subsidiaries of Subsidiary 13.

Subsidiaries 8, 18, 23, 24, 25, 26, 32, 35, and 61 are wholly-owned subsidiaries of Subsidiary 16.

Subsidiary 17 is owned 99.9999% by Subsidiary 16 and 0.001% by Subsidiary 1.

Subsidiary 19 is owned 99.231 % by Subsidiary 16 and 0.769% by Subsidiary 13.

Subsidiary 20
is owned 99.99% by Subsidiary 16 and 0.01% by Pharmaceutical Product Development, Inc.

Subsidiary 21 is owned 95% by Subsidiary 16 and 5% by
Subsidiary 1.

Subsidiary 22 is owned 99% by Subsidiary 16 and 1% by Subsidiary 1.

Subsidiaries 27 and 28 are wholly-owned subsidiaries of Subsidiary 26.

Subsidiary 29 is owned 97.78% by Subsidiary 26 and 2.22% by Subsidiary 16.

Subsidiary 30 is owned
72% by Subsidiary 26 and 28% by Subsidiary 27.

Subsidiary 31 is owned 96.67% by Subsidiary 26 and 3.33% by Subsidiary 16.

Subsidiary 33 is owned 99.99% by Subsidiary 16 and 0.01% by Subsidiary 13.

Subsidiary 34 is owned 99.99% by Subsidiary 16 and 1 share is held by each of Subsidiary 7, Subsidiary 11, Subsidiary 36, Subsidiary 45, Subsidiary 46, and 1 individual.

Subsidiaries 36, 40, 41, 42, 43, 45, 47, 55, 57, 62, 63, and 66 are wholly-owned subsidiaries of Subsidiary 11.

Subsidiary 37 is owned 99% by Subsidiary 36 and 1% by Subsidiary 11.

Subsidiary 38 is owned 50% by Subsidiary 11 and 50% by Subsidiary 36.

Subsidiary 39 is a
wholly-owned subsidiary of Subsidiary 36.

Subsidiary 44 is 99.9% owned by Subsidiary 11 and .1% by Subsidiary 36.

Subsidiary 46 is 50% owned by Subsidiary 45 and 50% by Subsidiary 1.

Subsidiary 48 is owned 99.99% by Subsidiary 11 and 0.01% by Subsidiary 36.

Subsidiary 50 is owned
85% by Subsidiary 11 and 15% by Subsidiary 36.

Subsidiary 51 is owned 99% by Subsidiary 16 and 1% by Subsidiary 1.

Subsidiary 53 is a wholly-owned subsidiary of Subsidiary 45.

Subsidiary 54 is owned 99.95% by Subsidiary 11 and 0.05% by Subsidiary 47.

Subsidiary 56 is a
wholly-owned subsidiary of Subsidiary 54.

Subsidiary 58 is a wholly-owned subsidiary of Subsidiary 56.

Subsidiary 11 is 99.6% owned by Subsidiary 16 and 0.4% by Subsidiary 61.

Subsidiary 64 is wholly-owned subsidiary of Subsidiary 63.

Subsidiary 65 is wholly-owned
subsidiary of Subsidiary 64.

Subsidiary 67 and 70 is wholly-owned subsidiary of Subsidiary 66.

Subsidiary 68 is 85% owned by Subsidiary 67 and 15% by a Chinese entity.

Subsidiary 69 is 80% owned by Subsidiary 67, 5% by Subsidiary 68, and 15% by a Chinese entity.

Subsidiary 71 is 80% owned by Subsidiary 6 and 20% owned by Subsidiary 16.

Subsidiaries 72, 74, and 75 are wholly-owned subsidiaries
of Subsidiary 61.

Subsidiary 73 is 99.3% owned by Subsidiary 61 and 0.7% owned by Subsidiary 62.

Subsidiary 76 is 75% owned by Subsidiary 62 and 25% owned by Subsidiary 61.



3