##### Table of Contents

---

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549



---

FORM 10-Q



---

(Mark One)

|x | QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
|- | ---------------------------------------------------------------------------------------

For the quarterly period ended June 30, 2006

or



| ̈ | TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
|- | ----------------------------------------------------------------------------------------

For the transition period from  to

Commission file number: 000-30267



---

ORCHID CELLMARK INC.

(Exact name of registrant as specified in its charter)



---



|                                                               |  |                                     
|-------------------------------------------------------------- |  | ------------------------------------
|Delaware                                                       |  | 22-3392819                          
|(State or other jurisdiction of incorporation or organization) |  | (I.R.S. Employer Identification No.)
|                                                               | 
|4390 US Route One Princeton, NJ                                |  | 08540                               
|(Address of principal executive offices)                       |  | (Zip code)                          

Registrants telephone number, including area code: (609) 750-2200



---

Indicate by check mark whether the
registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and
(2) has been subject to such filing requirements for the past 90 days.    Yes  x    No ̈

Indicate by check mark whether the registrant is a large accelerated
filer, an accelerated filer, or a non-accelerated filer. See definition of accelerated filer and large accelerated filer in Rule 12b-2 of the Exchange Act. (Check one):

Large accelerated filer ̈Accelerated filer  x    Non-accelerated filer ̈

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the
Exchange Act)    Yes ̈No  x

As of August 7, 2006, the registrant had 24,375,143 shares of common stock outstanding.



---



---

##### Table of Contents

ORCHID CELLMARK INC.

INDEX TO FORM 10-Q



|                              |  |                                                                                                              |  |     
|----------------------------- |  | ------------------------------------------------------------------------------------------------------------ |  | ----
|                              |  |                                                                                                              |  | Page
|PART I. FINANCIAL INFORMATION
|ITEM 1.                       |  | Financial Statements (unaudited)                                                                             |  | 1   
|                              |  | Consolidated Balance Sheets as of June 30, 2006 and December 31, 2005                                        |  | 1   
|                              |  | Consolidated Statements of Operations for the three and six months ended June 30, 2006 and 2005 (restated)   |  | 2   
|                              |  | Consolidated Statements of Cash Flows for the six months ended June 30, 2006 and 2005 (restated)             |  | 3   
|                              |  | Consolidated Statement of Stockholders Equity and Comprehensive Loss for the six months ended June 30, 2006 |  | 4   
|                              |  | Notes to Consolidated Financial Statements                                                                   |  | 5   
|ITEM 2.                       |  | Managements Discussion and Analysis of Financial Condition and Results of Operations                        |  | 14  
|ITEM 3.                       |  | Quantitative and Qualitative Disclosures about Market Risk                                                   |  | 23  
|ITEM 4.                       |  | Controls and Procedures                                                                                      |  | 24  
|                             
|PART II. OTHER INFORMATION   
|ITEM 1.                       |  | Legal Proceedings                                                                                            |  | 25  
|ITEM 1A.                      |  | Risk Factors                                                                                                 |  | 26  
|ITEM 2.                       |  | Unregistered Sales of Equity Securities and Use of Proceeds                                                  |  | 27  
|ITEM 3.                       |  | Defaults Upon Senior Securities                                                                              |  | 27  
|ITEM 4.                       |  | Submission of Matters to a Vote of Security Holders                                                          |  | 27  
|ITEM 5.                       |  | Other Information                                                                                            |  | 27  
|ITEM 6.                       |  | Exhibits                                                                                                     |  | 27  
|                              | 
|SIGNATURES                    |  | 28                                                                                                          



---

##### Table of Contents

PART I  FINANCIAL INFORMATION

Item 1. FINANCIAL STATEMENTS

ORCHID CELLMARK INC. AND SUBSIDIARIES

Consolidated Balance Sheets

(In thousands, except share and per share data)

(Unaudited)



|                                                                                                                                                                                                                                                |  |              |          |   |                  |   |          |  
|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |  | ------------ | -------- | - | ---------------- | - | -------- | -
|                                                                                                                                                                                                                                                |  | June 30,2006 |          |   | December 31,2005 |  
|Assets                                                                                                                                                                                                                                          |  |              |          |   |                  |   |          |  
|Current assets:                                                                                                                                                                                                                                 |  |              |          |   |                  |   |          |  
|Cash and cash equivalents                                                                                                                                                                                                                       |  | $            | 11,482   |   |                  | $ | 23,198   |  
|Restricted cash                                                                                                                                                                                                                                 |  |              |         |   |                  |   | 566      |  
|Accounts receivable, net                                                                                                                                                                                                                        |  |              | 11,757   |   |                  |   | 10,693   |  
|Inventory                                                                                                                                                                                                                                       |  |              | 936      |   |                  |   | 1,054    |  
|Prepaids and other current assets                                                                                                                                                                                                               |  |              | 2,037    |   |                  |   | 1,904    |  
|                                                                                                                                                                                                                                                |  |              |          |   |                  |   |          |  
|Total current assets                                                                                                                                                                                                                            |  |              | 26,212   |   |                  |   | 37,415   |  
|Fixed assets, net                                                                                                                                                                                                                               |  |              | 8,839    |   |                  |   | 9,096    |  
|Goodwill                                                                                                                                                                                                                                        |  |              | 2,235    |   |                  |   | 2,177    |  
|Other intangibles, net                                                                                                                                                                                                                          |  |              | 10,548   |   |                  |   | 11,358   |  
|Restricted cash                                                                                                                                                                                                                                 |  |              | 975      |   |                  |   | 1,170    |  
|Other assets                                                                                                                                                                                                                                    |  |              | 489      |   |                  |   | 453      |  
|                                                                                                                                                                                                                                                |  |              |          |   |                  |   |          |  
|Total assets                                                                                                                                                                                                                                    |  | $            | 49,298   |   |                  | $ | 61,669   |  
|                                                                                                                                                                                                                                                |  |              |          |   |                  |   |          |  
|Liabilities and Stockholders Equity                                                                                                                                                                                                            |  |              |          |   |                  |   |          |  
|Current liabilities:                                                                                                                                                                                                                            |  |              |          |   |                  |   |          |  
|Accounts payable                                                                                                                                                                                                                                |  | $            | 2,901    |   |                  | $ | 3,466    |  
|Accrued expenses and other current liabilities                                                                                                                                                                                                  |  |              | 6,679    |   |                  |   | 9,077    |  
|Income taxes payable                                                                                                                                                                                                                            |  |              | 648      |   |                  |   | 1,212    |  
|Deferred revenue                                                                                                                                                                                                                                |  |              | 886      |   |                  |   | 825      |  
|                                                                                                                                                                                                                                                |  |              |          |   |                  |   |          |  
|Total current liabilities                                                                                                                                                                                                                       |  |              | 11,114   |   |                  |   | 14,580   |  
|                                                                                                                                                                                                                                                |  |             
|Accrued restructuring, less current portion                                                                                                                                                                                                     |  |              | 165      |   |                  |   | 329      |  
|Other liabilities                                                                                                                                                                                                                               |  |              | 1,602    |   |                  |   | 1,283    |  
|                                                                                                                                                                                                                                                |  |              |          |   |                  |   |          |  
|Total liabilities                                                                                                                                                                                                                               |  |              | 12,881   |   |                  |   | 16,192   |  
|                                                                                                                                                                                                                                                |  |              |          |   |                  |   |          |  
|Commitments and contingencies                                                                                                                                                                                                                   |  |              |          |   |                  |   |          |  
|Stockholders equity:                                                                                                                                                                                                                           |  |              |          |   |                  |   |          |  
|Preferred stock; $.001 per share par value; authorized 5,000,000 shares; designated 1,680 Series A redeemable convertible shares and 1,000,000
Series A junior participating shares; no shares issued or outstanding                            |  |              |         |   |                  |   |         |  
|Common stock, $.001 par value; authorized 150,000,000 shares; issued 24,507,000 and 24,495,000 at June 30, 2006 and December 31,
2005, respectively; outstanding 24,344,000 and 24,332,000 at June 30, 2006 and December 31, 2005, respectively |  |              | 24       |   |                  |   | 24       |  
|Additional paid-in capital                                                                                                                                                                                                                      |  |              | 352,098  |   |                  |   | 351,553  |  
|Accumulated other comprehensive income                                                                                                                                                                                                          |  |              | 2,464    |   |                  |   | 1,240    |  
|Treasury stock at cost, 163,259 common shares at June 30, 2006 and December 31, 2005                                                                                                                                                            |  |              | (1,587   | ) |                  |   | (1,587   | )
|Accumulated deficit                                                                                                                                                                                                                             |  |              | (316,582 | ) |                  |   | (305,753 | )
|                                                                                                                                                                                                                                                |  |              |          |   |                  |   |          |  
|Total stockholders equity                                                                                                                                                                                                                      |  |              | 36,417   |   |                  |   | 45,477   |  
|                                                                                                                                                                                                                                                |  |              |          |   |                  |   |          |  
|Total liabilities and stockholders equity                                                                                                                                                                                                      |  | $            | 49,298   |   |                  | $ | 61,669   |  
|                                                                                                                                                                                                                                                |  |              |          |   |                  |   |          |  

See accompanying notes to consolidated financial statements.



1



---

##### Table of Contents

ORCHID CELLMARK INC. AND SUBSIDIARIES

Consolidated Statements of Operations

Three and six months ended June 30, 2006 and 2005

(In thousands, except per share data)

(Unaudited)



|                                                              |  |                            |        |   |                          |   |        |      |  |   |                        |   |  |   |        |  
|------------------------------------------------------------- |  | -------------------------- | ------ | - | ------------------------ | - | ------ | ---- |  | - | ---------------------- | - |  | - | ------ | -
|                                                              |  | Three months endedJune 30, |        |   | Six months endedJune 30, |  
|                                                              |  | 2006                       |        |   | 2005                     |   |        | 2006 |  |   | 2005                   |  
|                                                              |  |                            |        |   | (Restated, see Note 2)   |   |        |      |  |   | (Restated, see Note 2) |  
|Revenues:                                                     |  |                            |        |   |                          |   |        |      |  |   |                        |   |  |   |        |  
|Service revenues                                              |  | $                          | 13,549 |   |                          | $ | 15,738 |      |  | $ | 26,032                 |   |  | $ | 30,227 |  
|Other revenues                                                |  |                            | 64     |   |                          |   | 99     |      |  |   | 176                    |   |  |   | 275    |  
|                                                              |  |                            |        |   |                          |   |        |      |  |   |                        |   |  |   |        |  
|Total revenues                                                |  |                            | 13,613 |   |                          |   | 15,837 |      |  |   | 26,208                 |   |  |   | 30,502 |  
|                                                              |  |                            |        |   |                          |   |        |      |  |   |                        |   |  |   |        |  
|Operating expenses:                                           |  |                            |        |   |                          |   |        |      |  |   |                        |   |  |   |        |  
|Cost of service revenues                                      |  |                            | 9,919  |   |                          |   | 9,042  |      |  |   | 20,123                 |   |  |   | 18,066 |  
|Research and development                                      |  |                            | 316    |   |                          |   | 417    |      |  |   | 594                    |   |  |   | 814    |  
|Marketing and sales                                           |  |                            | 1,750  |   |                          |   | 1,947  |      |  |   | 3,965                  |   |  |   | 3,725  |  
|General and administrative                                    |  |                            | 4,778  |   |                          |   | 4,912  |      |  |   | 10,593                 |   |  |   | 9,551  |  
|Restructuring                                                 |  |                            | 432    |   |                          |   | 358    |      |  |   | 486                    |   |  |   | 477    |  
|Amortization of intangible assets                             |  |                            | 441    |   |                          |   | 430    |      |  |   | 880                    |   |  |   | 861    |  
|                                                              |  |                            |        |   |                          |   |        |      |  |   |                        |   |  |   |        |  
|Total operating expenses                                      |  |                            | 17,636 |   |                          |   | 17,106 |      |  |   | 36,641                 |   |  |   | 33,494 |  
|                                                              |  |                            |        |   |                          |   |        |      |  |   |                        |   |  |   |        |  
|Operating loss                                                |  |                            | (4,023 | ) |                          |   | (1,269 | )    |  |   | (10,433                | ) |  |   | (2,992 | )
|Other income (expense):                                       |  |                            |        |   |                          |   |        |      |  |   |                        |   |  |   |        |  
|Interest income                                               |  |                            | 156    |   |                          |   | 92     |      |  |   | 329                    |   |  |   | 188    |  
|Interest expense                                              |  |                            |       |   |                          |   | (6     | )    |  |   |                       |   |  |   | (15    | )
|Other income (expense)                                        |  |                            | (153   | ) |                          |   | 1,617  |      |  |   | (344                   | ) |  |   | 1,620  |  
|                                                              |  |                            |        |   |                          |   |        |      |  |   |                        |   |  |   |        |  
|Total other income (expense), net                             |  |                            | 3      |   |                          |   | 1,703  |      |  |   | (15                    | ) |  |   | 1,793  |  
|                                                              |  |                            |        |   |                          |   |        |      |  |   |                        |   |  |   |        |  
|Income (loss) before income taxes                             |  |                            | (4,020 | ) |                          |   | 434    |      |  |   | (10,448                | ) |  |   | (1,199 | )
|Income tax expense                                            |  |                            | 210    |   |                          |   | 616    |      |  |   | 381                    |   |  |   | 635    |  
|                                                              |  |                            |        |   |                          |   |        |      |  |   |                        |   |  |   |        |  
|Net loss                                                      |  | $                          | (4,230 | ) |                          | $ | (182   | )    |  | $ | (10,829                | ) |  | $ | (1,834 | )
|                                                              |  |                            |        |   |                          |   |        |      |  |   |                        |   |  |   |        |  
|Basic and diluted net loss per share                          |  | $                          | (0.17  | ) |                          | $ | (0.01  | )    |  | $ | (0.44                  | ) |  | $ | (0.08  | )
|                                                              |  |                            |        |   |                          |   |        |      |  |   |                        |   |  |   |        |  
|Shares used in computing basic and diluted net loss per share |  |                            | 24,339 |   |                          |   | 24,394 |      |  |   | 24,336                 |   |  |   | 24,218 |  

See accompanying notes to consolidated financial statements.



2



---

##### Table of Contents

ORCHID CELLMARK INC. AND SUBSIDIARIES

Consolidated Statements of Cash Flows

Six months ended June 30, 2006 and 2005

(In thousands)

(Unaudited)



|                                                                            |  |      |         |   |                        |   |        |  
|--------------------------------------------------------------------------- |  | ---- | ------- | - | ---------------------- | - | ------ | -
|                                                                            |  | 2006 |         |   | 2005                   |  
|                                                                            |  |      |         |   | (Restated, see Note 2) |  
|Cash flows from operating activities:                                       |  |      |         |   |                        |   |        |  
|Net loss                                                                    |  | $    | (10,829 | ) |                        | $ | (1,834 | )
|Adjustments to reconcile net loss to net cash used in operating activities: |  |      |         |   |                        |   |        |  
|Non-cash gain on escrow settlement                                          |  |      |        |   |                        |   | (1,587 | )
|Stock-based compensation                                                    |  |      | 501     |   |                        |   | 104    |  
|(Gain) loss on sale of assets                                               |  |      | 10      |   |                        |   | (7     | )
|Impairment charge on available-for-sale securities                          |  |      | 259     |   |                        |   |       |  
|Depreciation and amortization                                               |  |      | 2,637   |   |                        |   | 2,768  |  
|Bad debt expense                                                            |  |      | 66      |   |                        |   | 88     |  
|Changes in assets and liabilities:                                          |  |      |         |   |                        |   |        |  
|Accounts receivable                                                         |  |      | (1,130  | ) |                        |   | 2,296  |  
|Inventory                                                                   |  |      | 118     |   |                        |   | (241   | )
|Prepaids and other current assets                                           |  |      | (133    | ) |                        |   | (426   | )
|Other assets                                                                |  |      | (15     | ) |                        |   | 4      |  
|Accounts payable                                                            |  |      | (565    | ) |                        |   | 488    |  
|Accrued expenses, including restructuring                                   |  |      | (2,562  | ) |                        |   | (2,968 | )
|Income taxes payable                                                        |  |      | (564    | ) |                        |   | (169   | )
|Deferred revenue                                                            |  |      | 61      |   |                        |   | (71    | )
|Other liabilities                                                           |  |      | 319     |   |                        |   |       |  
|                                                                            |  |      |         |   |                        |   |        |  
|Net cash used in operating activities                                       |  |      | (11,827 | ) |                        |   | (1,555 | )
|                                                                            |  |      |         |   |                        |   |        |  
|Cash flows from investing activities:                                       |  |      |         |   |                        |   |        |  
|Capital expenditures                                                        |  |      | (1,295  | ) |                        |   | (1,113 | )
|Decrease in restricted cash                                                 |  |      | 761     |   |                        |   |       |  
|Proceeds from the sale of assets                                            |  |      |        |   |                        |   | 49     |  
|Sales of short-term investments                                             |  |      |        |   |                        |   | 3,668  |  
|                                                                            |  |      |         |   |                        |   |        |  
|Net cash provided by (used in) investing activities                         |  |      | (534    | ) |                        |   | 2,604  |  
|                                                                            |  |      |         |   |                        |   |        |  
|Cash flows from financing activities:                                       |  |      |         |   |                        |   |        |  
|Net proceeds from issuance of common stock                                  |  |      | 44      |   |                        |   | 263    |  
|Repayment of debt from line of credit                                       |  |      |        |   |                        |   | (286   | )
|                                                                            |  |      |         |   |                        |   |        |  
|Net cash provided by (used in) financing activities                         |  |      | 44      |   |                        |   | (23    | )
|                                                                            |  |      |         |   |                        |   |        |  
|Effect of foreign currency translation on cash and cash equivalents         |  |      | 601     |   |                        |   | (426   | )
|                                                                            |  |      |         |   |                        |   |        |  
|Net increase (decrease) in cash and cash equivalents                        |  |      | (11,716 | ) |                        |   | 600    |  
|Cash and cash equivalents at beginning of period                            |  |      | 23,198  |   |                        |   | 12,112 |  
|                                                                            |  |      |         |   |                        |   |        |  
|Cash and cash equivalents at end of period                                  |  | $    | 11,482  |   |                        | $ | 12,712 |  
|                                                                            |  |      |         |   |                        |   |        |  

See accompanying notes to consolidated financial statements.



3



---

##### Table of Contents

ORCHID CELLMARK INC. AND SUBSIDIARIES

Consolidated Statement of Stockholders Equity and Comprehensive
Loss

Six months ended June 30, 2006

(In thousands)

(Unaudited)



|                                                                                                        |  |                  |  |        |    |                            |   |                                     |  |               |       |  |                    |        |   |                            |   |          |   |  |   |         |  
|------------------------------------------------------------------------------------------------------- |  | ---------------- |  | ------ | -- | -------------------------- | - | ----------------------------------- |  | ------------- | ----- |  | ------------------ | ------ | - | -------------------------- | - | -------- | - |  | - | ------- | -
|                                                                                                        |  | Common Stock     |  |        |    |                            |   |                                     |  |               |       |  |                    |        |  
|                                                                                                        |  | Number of Shares |  | Amount |    | Additional Paid-in Capital |   | AccumulatedOtherComprehensiveIncome |  | TreasuryStock |       |  | AccumulatedDeficit |        |   | Total Stockholders Equity |  
|Balance at January 1, 2006                                                                              |  | 24,495           |  | $      | 24 |                            | $ | 351,553                             |  | $             | 1,240 |  | $                  | (1,587 | ) |                            | $ | (305,753 | ) |  | $ | 45,477  |  
|Net loss                                                                                                |  |                 |  |        |   |                            |   |                                    |  |               |      |  |                    |       |   |                            |   | (10,829  | ) |  |   | (10,829 | )
|Foreign currency translation adjustment                                                                 |  |                 |  |        |   |                            |   |                                    |  |               | 944   |  |                    |       |   |                            |   |         |   |  |   | 944     |  
|Unrealized gain on available-for-sale securities                                                        |  |                 |  |        |   |                            |   |                                    |  |               | 21    |  |                    |       |   |                            |   |         |   |  |   | 21      |  
|Reclassification adjustment for impairment charge on available-for-sale securities included in net loss |  |                 |  |        |   |                            |   |                                    |  |               | 259   |  |                    |       |   |                            |   |         |   |  |   | 259     |  
|                                                                                                        |  |                  |  |        |    |                            |   |                                     |  |               |       |  |                    |        |   |                            |   |          |   |  |   |         |  
|Comprehensive loss                                                                                      |  |                  |  |        |    |                            |   |                                     |  |               |       |  |                    |        |   |                            |   |          |   |  |   | (9,605  | )
|                                                                                                        |  |                  |  |        |    |                            |   |                                     |  |               |       |  |                    |        |   |                            |   |          |   |  |   |         |  
|Issuance of common stock from exercise of stock options                                                 |  | 12               |  |        |   |                            |   | 44                                  |  |               |      |  |                    |       |   |                            |   |         |   |  |   | 44      |  
|Stock-based compensation expense                                                                        |  |                 |  |        |   |                            |   | 501                                 |  |               |      |  |                    |       |   |                            |   |         |   |  |   | 501     |  
|                                                                                                        |  |                  |  |        |    |                            |   |                                     |  |               |       |  |                    |        |   |                            |   |          |   |  |   |         |  
|Balance at June 30, 2006                                                                                |  | 24,507           |  | $      | 24 |                            | $ | 352,098                             |  | $             | 2,464 |  | $                  | (1,587 | ) |                            | $ | (316,582 | ) |  | $ | 36,417  |  
|                                                                                                        |  |                  |  |        |    |                            |   |                                     |  |               |       |  |                    |        |   |                            |   |          |   |  |   |         |  

See accompanying notes to consolidated financial statements.



4



---

##### Table of Contents

ORCHID CELLMARK INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

(Unaudited)

(1) Basis of Presentation

The accompanying unaudited consolidated financial statements of Orchid Cellmark Inc. (previously known as Orchid Biosciences, Inc.) and
its subsidiaries (the Company) have been prepared in accordance with accounting principles generally accepted in the United States of America (US) for interim financial information and with the instructions to Form 10-Q and Article 10 of Regulation
S-X. Accordingly, they do not include all of the information and footnotes required by accounting principles generally accepted in the US for complete annual financial statements. In the opinion of management, all adjustments, consisting of normal
recurring adjustments, considered necessary for a fair presentation have been included. Interim results are not necessarily indicative of results that may be expected for a full year.

The accompanying unaudited consolidated financial statements should be read in conjunction with the audited consolidated financial statements and
footnotes thereto included in the Companys Annual Report on Form 10-K for the year ended December 31, 2005, as filed with the Securities and Exchange Commission (SEC).

Since the date of the Annual Report on Form 10-K for the year ended December 31, 2005, there have been no material changes to the Companys
critical accounting policies, with the exception of stock-based compensation (see Note 2).

Certain prior period amounts have been
reclassified to conform to the current year presentation.

(2) Restatement of Consolidated Financial Statements

On May 31, 2005, the Company entered into a settlement of escrow claims associated with its December 2001 acquisition of Lifecodes Corporation. The
Company has determined that the 163,259 shares of the Companys common stock received from this settlement and valued at $1.6 million should have been recorded at the settlement date as a non-operating gain and an acquisition of treasury stock
in the Companys previously filed consolidated financial statements included in the Companys Form 10-Q for the quarter ended June 30, 2005. As a result of this restatement, other income increased and net loss decreased by $1.6
million. This restatement did not have any impact on the cash flows of the Company.

The following tables summarize the impact of the
restatement discussed above on the previously issued unaudited financial data for the quarterly period ended June 30, 2005 (in thousands, except per share data):



|                                                              |  |                                  |        |   |                                |   |       |             |  |   |                        |   |  |            |        |   |             |   |       |   |  |   |        |  
|------------------------------------------------------------- |  | -------------------------------- | ------ | - | ------------------------------ | - | ----- | ----------- |  | - | ---------------------- | - |  | ---------- | ------ | - | ----------- | - | ----- | - |  | - | ------ | -
|                                                              |  | Three Months Ended June 30, 2005 |        |   | Six Months Ended June 30, 2005 |  
|                                                              |  | As Previously Reported           |        |   | Adjustment                     |   |       | As Restated |  |   | As Previously Reported |   |  | Adjustment |        |   | As Restated |  
|Consolidated Statement of Operations:                         |  |                                  |        |   |                                |   |       |             |  |   |                        |   |  |            |        |   |             |   |       |   |  |   |        |  
|Other income (expense)                                        |  | $                                | 30     |   |                                | $ | 1,587 |             |  | $ | 1,617                  |   |  | $          | 33     |   |             | $ | 1,587 |   |  | $ | 1,620  |  
|Total other income (expense), net                             |  |                                  | 116    |   |                                |   | 1,587 |             |  |   | 1,703                  |   |  |            | 206    |   |             |   | 1,587 |   |  |   | 1,793  |  
|Income (loss) before income taxes                             |  |                                  | (1,153 | ) |                                |   | 1,587 |             |  |   | 434                    |   |  |            | (2,786 | ) |             |   | 1,587 |   |  |   | (1,199 | )
|Net loss                                                      |  |                                  | (1,769 | ) |                                |   | 1,587 |             |  |   | (182                   | ) |  |            | (3,421 | ) |             |   | 1,587 |   |  |   | (1,834 | )
|Basic and diluted net loss per share                          |  | $                                | (0.07  | ) |                                | $ | 0.06  |             |  | $ | (0.01                  | ) |  | $          | (0.14  | ) |             | $ | 0.06  |   |  | $ | (0.08  | )
|Shares used in computing basic and diluted net loss per share |  |                                  | 24,448 |   |                                |   | (54   | )           |  |   | 24,394                 |   |  |            | 24,245 |   |             |   | (27   | ) |  |   | 24,218 |  



|                                     |  |                                |        |   |            |   |        |             |  |   |        |  
|------------------------------------ |  | ------------------------------ | ------ | - | ---------- | - | ------ | ----------- |  | - | ------ | -
|                                     |  | Six Months Ended June 30, 2005 |       
|                                     |  | As Previously Reported         |        |   | Adjustment |   |        | As Restated | 
|Consolidated Statement of Cash Flows |  |                                |        |   |            |   |        |             |  |   |        |  
|Net loss                             |  | $                              | (3,421 | ) |            | $ | 1,587  |             |  | $ | (1,834 | )
|Non-cash gain on escrow settlement   |  |                                |       |   |            |   | (1,587 | )           |  |   | (1,587 | )



5



---

##### Table of Contents

ORCHID CELLMARK INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS(Continued)

(Unaudited)



In addition, the Company incorrectly calculated the pro forma disclosure
of the compensation cost for options based on the fair value method for its stock options under Statement of Financial Accounting Standards (SFAS) No. 123, Accounting for Stock-Based Compensation(SFAS 123) for the quarter ended
June 30, 2005. The restated pro forma SFAS 123 disclosure for the three months and six months ended June 30, 2005 is presented in Note 3 below.

(3) Stock-based Compensation

During 1995, the Company established the 1995 Stock Incentive Plan (the 1995 Plan), which
provided for the granting of restricted common stock or incentive and nonqualified stock options to the Companys directors, employees and consultants. An aggregate of 700,000 shares of the Companys common stock was authorized for
issuance under the 1995 Plan, which expired by its terms on November 28, 2005.

During 2000, the Board of Directors and stockholders
of the Company approved the 2000 Employee, Director, and Consultant Stock Incentive Plan (the 2000 Plan) for the issuance of common stock, incentive stock options and nonqualified stock options to the Companys employees, directors and
consultants. The Company was originally authorized to issue options for up to 900,000 shares of the Companys common stock under the 2000 Plan. On June 8, 2005, at the Companys Annual Meeting of Stockholders, the stockholders
approved the Companys Amended and Restated 2005 Stock Plan (the 2005 Plan). The 2005 Plan amended and restated in its entirety the 2000 Plan. The 2005 Plan authorizes the grant of up to approximately 1,700,000 shares plus the number of
additional shares as described in the 2005 Plan, for the issuance of incentive stock options, nonqualified stock options, stock grants and other stock-based awards to the Companys employees, directors and consultants. The 2005 Plan also
specifies other terms such as eligibility, annual limits and the grant of awards thereunder. The 1995 Plan and the 2005 Plan provide that in the event of a change in control in the beneficial ownership of the Company, as defined therein, all options
may, at the discretion of the compensation committee of the Companys Board of Directors, become fully vested and exercisable immediately prior to the change in control.

Stock options granted under the 2005 Plan are not granted at a price less than the fair market value of the Companys common stock at the date of
grant. Stock options granted to employees in general vest over four years in equal monthly installments and have a maximum term of ten years. Stock options granted to the Companys Board of Directors in general vest over three years in equal
monthly installments and have a maximum term of ten years. The Company issues new shares of its common stock upon exercise of stock options.

The Company uses the Black-Scholes option pricing model to estimate the fair value of options granted, which requires the input of highly subjective assumptions. These assumptions include estimating the length of time employees will
retain their vested stock options before exercising them, the estimated volatility of the Companys common stock price over the expected term and the number of options that will ultimately not vest. Changes in the subjective assumptions can
materially affect the estimate of the fair value of stock-based compensation and, consequently, the related amount of compensation expense recognized in the consolidated statement of operations.

The following assumptions were used in valuing the options granted during the three and six months ended June 30, 2006 and 2005:



|                        |  |                            |   |  |                          |   |  |         |   |  |         |  
|----------------------- |  | -------------------------- | - |  | ------------------------ | - |  | ------- | - |  | ------- | -
|                        |  | Three months ended June 30 |   |  | Six months ended June 30 |  
|                        |  | 2006                       |   |  | 2005                     |   |  | 2006    |   |  | 2005    |  
|Risk-free interest rate |  | 5.00                       | % |  | 3.79                     | % |  | 4.93    | % |  | 3.84    | %
|Volatility              |  | 85                         | % |  | 85                       | % |  | 85      | % |  | 85      | %
|Expected option term    |  | 6 years                    |   |  | 5 years                  |   |  | 6 years |   |  | 5 years |  
|Expected dividend yield |  | 0                          | % |  | 0                        | % |  | 0       | % |  | 0       | %

The risk-free interest rate assumption is based upon the US Treasury yields in effect at the time
of grant for periods closest to the expected term of the option. The expected volatility assumption is based on the daily historical volatility of the Companys stock price, over the expected life of the option. The Companys stock options
are considered plain vanilla options based on the guidance in SEC Staff Accounting Bulletin No. 107, Share-Based Payment,and as such the Company has elected the use of the simplified method, whereby the Company
has assumed that all options will be exercised midway between the vesting date and the contractual term of the option to determine the expected term of the option. As the Company has not paid dividends since inception, nor does it expect to pay any
dividends for the foreseeable future, the expected dividend yield assumption is zero.



6



---

##### Table of Contents

ORCHID CELLMARK INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS(Continued)

(Unaudited)



Prior to January 1, 2006, the Company applied the
disclosure-only provisions of SFAS 123. In accordance with the provisions of SFAS 123, the Company applied Accounting Principles Board Opinion No. 25, Accounting for Stock Issued to Employees, and related interpretations in accounting
for its stock-based compensation plans and, accordingly, compensation cost was recorded on the date of issuance or grant as the excess of the market price of the underlying stock over the purchase or exercise price. Any deferred compensation cost
was amortized over the respective vesting periods of the equity instruments, if any.

Effective January 1, 2006, the Company adopted
the provisions of, and accounts for stock-based compensation in accordance with, SFAS No. 123(R), Share-Based Payment(SFAS 123(R)). Under the fair value recognition provisions of this statement, stock-based compensation cost is measured
at the grant date based on the fair value of the award and is recognized as expense over the requisite service period, which is the vesting period. The Company has applied the modified prospective method of adoption, under which prior periods are
not restated for comparative purposes. Under the modified prospective method, SFAS 123(R) applies to new awards and to awards that were outstanding as of December 31, 2005 that are subsequently modified, repurchased or cancelled. Compensation
expense recognized during the six months ended June 30, 2006 includes the expense for all share-based payments granted prior to, but not yet vested as of, December 31, 2005, based on the grant date fair value estimated in accordance with
the original provisions of SFAS 123, and the expense for all share-based payments granted during the six months ended June 30, 2006, based on the grant date fair value estimated in accordance with the provisions of SFAS 123(R). Stock-based
compensation is classified within cost of service revenues, research and development, marketing and sales and general and administrative expense in the consolidated statement of operations. As stock-based compensation expense recognized in the
consolidated statement of operations is based on awards ultimately expected to vest, the amount of expense has been reduced for estimated forfeitures. SFAS 123(R) requires forfeitures to be estimated at the time of grant and revised, if necessary,
in subsequent periods if actual forfeitures differ from those estimates. Forfeitures are estimated based on historical experience.

In
November 2005, the Financial Accounting Standards Board (FASB) issued FASB Staff Position No. 123(R)-3, Transition Election Related to Accounting for the Tax Effects of Share-Based Payment Awards. The Company has elected not to adopt the
short-cut method to calculate the beginning balance of the hypothetical additional paid-in-capital (APIC) pool of the excess tax benefits upon the Companys adoption of SFAS 123(R). Utilizing the long-haul method, the Company has determined
that it has no hypothetical APIC pool that can be utilized to offset future shortfalls that may be incurred.

The Companys option
grants include options which qualify as incentive stock options (ISO) for income tax purposes. The treatment of the potential tax deduction, if any, related to ISOs may cause variability in the Companys effective tax rate in future periods. In
the period the compensation cost related to ISOs is recorded, a corresponding tax benefit is not recorded as it is assumed that the Company will not receive a tax deduction upon the exercise of such ISOs. The Company may be eligible for tax
deductions in subsequent periods to the extent that there is a disqualifying disposition of the common stock underlying the ISO. In such cases, the Company would record a tax benefit through the consolidated statement of operations in an amount not
to exceed the corresponding cumulative compensation cost recorded in the financial statements for the particular options multiplied by the statutory tax rate. Any incremental tax benefit received by the Company in excess of the tax benefit recorded
in the statement of operations would be recorded directly to APIC when realized.

Net loss for the six months ended June 30, 2006
includes $0.5 million of compensation costs related to stock-based compensation arrangements. The Company did not capitalize any of the compensation costs for the six months ended June 30, 2006 in fixed assets, inventory or other assets. The
Company has not benefited from a tax deduction for stock option exercises due to net losses for the periods during which the options were exercised.



7



---

##### Table of Contents

ORCHID CELLMARK INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS(Continued)

(Unaudited)



The following table summarizes the impact of the pro forma
SFAS 123 disclosure restatement discussed above on the previously issued unaudited financial data for the three months and six months ended June 30, 2005, respectively (in thousands, except per share data) :



|                                                                                                              |  |                                  |        |   |                                |   |       |             |  |   |                        |   |  |            |        |   |             |   |       |   |  |   |        |  
|------------------------------------------------------------------------------------------------------------- |  | -------------------------------- | ------ | - | ------------------------------ | - | ----- | ----------- |  | - | ---------------------- | - |  | ---------- | ------ | - | ----------- | - | ----- | - |  | - | ------ | -
|                                                                                                              |  | Three Months Ended June 30, 2005 |        |   | Six Months Ended June 30, 2005 |  
|                                                                                                              |  | As Previously Reported           |        |   | Adjustment                     |   |       | As Restated |  |   | As Previously Reported |   |  | Adjustment |        |   | As Restated |  
|Net loss:                                                                                                     |  |                                  |        |   |                                |   |       |             |  |   |                        |   |  |            |        |   |             |   |       |   |  |   |        |  
|As reported                                                                                                   |  | $                                | (1,769 | ) |                                | $ | 1,587 |             |  | $ | (182                   | ) |  | $          | (3,421 | ) |             | $ | 1,587 |   |  | $ | (1,834 | )
|Add: Stock-based employee compensation expense included in reported net loss                                  |  |                                  |       |   |                                |   |      |             |  |   |                       |   |  |            | 104    |   |             |   |      |   |  |   | 104    |  
|Deduct: Total stock-based employee compensation expense determined under the fair value method for all awards |  |                                  | (249   | ) |                                |   | (478  | )           |  |   | (727                   | ) |  |            | (621   | ) |             |   | (373  | ) |  |   | (994   | )
|                                                                                                              |  |                                  |        |   |                                |   |       |             |  |   |                        |   |  |            |        |   |             |   |       |   |  |   |        |  
|Pro forma under SFAS 123                                                                                      |  | $                                | (2,018 | ) |                                | $ | 1,109 |             |  | $ | (909                   | ) |  | $          | (3,938 | ) |             | $ | 1,214 |   |  |   | (2,724 | )
|                                                                                                              |  |                                  |        |   |                                |   |       |             |  |   |                        |   |  |            |        |   |             |   |       |   |  |   |        |  
|Basic and diluted net loss per share:                                                                         |  |                                  |        |   |                                |   |       |             |  |   |                        |   |  |            |        |   |             |   |       |   |  |   |        |  
|As reported                                                                                                   |  | $                                | (0.07  | ) |                                | $ | 0.06  |             |  | $ | (0.01                  | ) |  | $          | (0.14  | ) |             | $ | 0.06  |   |  | $ | (0.08  | )
|Pro forma under SFAS 123                                                                                      |  |                                  | (0.08  | ) |                                |   | 0.04  |             |  |   | (0.04                  | ) |  |            | (0.16  | ) |             |   | 0.05  |   |  |   | (0.11  | )

A summary of activity for the six months ended June 30, 2006 and as of June 30, 2006
under the plans is as follows:



|                                         |  |           |   |  |                                 |       |                                           |      |                           |   |       
|---------------------------------------- |  | --------- | - |  | ------------------------------- | ----- | ----------------------------------------- | ---- | ------------------------- | - | ------
|                                         |  | Shares    |   |  | Weighted average exercise price |       | Weighted averageremainingcontractual term |      | Aggregate intrinsic value
|Options outstanding at December 31, 2005 |  | 1,233,954 |   |  | $                               | 12.35 |                                           |      |                           |   |       
|Granted                                  |  | 742,400   |   |  |                                 | 4.82  |                                           |      |                           |   |       
|Exercised                                |  | (12,201   | ) |  |                                 | 4.45  |                                           |      |                           |   |       
|Cancelled                                |  | (511,302  | ) |  |                                 | 8.28  |                                           |      |                           |   |       
|                                         |  |           |   |  |                                 |       |                                           |      |                           |   |       
|Options outstanding at June 30, 2006     |  | 1,452,851 |   |  |                                 | 10.01 |                                           | 8.22 |                           | $ | 61,000
|                                         |  |           |   |  |                                 |       |                                           |      |                           |   |       
|Options exercisable at June 30, 2006     |  | 627,474   |   |  |                                 | 15.24 |                                           | 6.61 |                           | $ | 61,000
|                                         |  |           |   |  |                                 |       |                                           |      |                           |   |       

Additional information about the Companys share-based payments is as follows (in thousands,
except per share data):



|                                                                    |  |                           |      |      |   |     
|------------------------------------------------------------------- |  | ------------------------- | ---- | ---- | - | ----
|                                                                    |  | Six months ended June 30,
|                                                                    |  | 2006                      |      | 2005
|Total intrinsic value of options exercised                          |  | $                         | 13   |      | $ | 401 
|Net cash proceeds from the exercise of stock options                |  |                           | 44   |      |   | 263 
|Weighted average grant date fair value per share of options granted |  |                           | 3.58 |      |   | 7.11

As of June 30, 2006, there was approximately $3.2 million of unrecognized compensation cost
related to stock options, which is expected to be recognized over a weighted average period of 3.36 years.

(4) Net Loss Per Share

Net loss per share is computed in accordance with SFAS No. 128, Earnings Per Share, by dividing the net loss by the weighted average number of
shares of common stock outstanding. During each period presented, the Company has certain options and warrants that have not been used in the calculation of diluted net loss per share because to do so would be anti-dilutive. As such, the numerator
and the denominator used in computing both basic and diluted net loss per share for each period are equal.



8



---

##### Table of Contents

ORCHID CELLMARK INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS(Continued)

(Unaudited)



(5) Inventory

Inventory is comprised of the following at June 30, 2006 and December 31, 2005 (in thousands):



|                 |  |               |     |                  |   |      
|---------------- |  | ------------- | --- | ---------------- | - | -----
|                 |  | June 30, 2006 |     | December 31,2005
|Raw materials    |  | $             | 742 |                  | $ | 511  
|Work in progress |  |               | 188 |                  |   | 523  
|Finished goods   |  |               | 6   |                  |   | 20   
|                 |  |               |     |                  |   |      
|                 |  | $             | 936 |                  | $ | 1,054
|                 |  |               |     |                  |   |      

Raw materials consist mainly of reagents, enzymes, chemicals and plates used in genotyping. Work
in progress consists mainly of case work not yet completed and DNA testing kits that are being processed. Finished goods consist mainly of DNA testing kits that have not yet been shipped.

(6) Goodwill and Other Intangible Assets

The
following table sets forth the activity during the six months ended June 30, 2006 as it relates to goodwill (in thousands):



|                                                          |  |   |      
|--------------------------------------------------------- |  | - | -----
|Balance as of December 31, 2005                           |  | $ | 2,177
|Other (due to the effect of foreign currency translation) |  |   | 58   
|                                                          |  |   |      
|Balance as of June 30, 2006                               |  | $ | 2,235
|                                                          |  |   |      

The following table sets forth the Companys other intangible assets at June 30, 2006
and December 31, 2005 (in thousands):



|                     |  |               |        |                          |   |         |     |  |          |        |                          |   |        |     |   |        |   |  |   |       
|-------------------- |  | ------------- | ------ | ------------------------ | - | ------- | --- |  | -------- | ------ | ------------------------ | - | ------ | --- | - | ------ | - |  | - | ------
|                     |  | June 30, 2006 |        | December 31, 2005       
|                     |  | Cost (1)      |        | Accumulated Amortization |   |         | Net |  | Cost (1) |        | Accumulated Amortization |   |        | Net
|Base technology      |  | $             | 6,080  |                          | $ | (3,338  | )   |  | $        | 2,742  |                          | $ | 6,054  |     | $ | (3,070 | ) |  | $ | 2,984 
|Customer list        |  |               | 5,253  |                          |   | (2,997  | )   |  |          | 2,256  |                          |   | 5,197  |     |   | (2,734 | ) |  |   | 2,463 
|Trademark/tradename  |  |               | 4,368  |                          |   | (1,938  | )   |  |          | 2,430  |                          |   | 4,323  |     |   | (1,738 | ) |  |   | 2,585 
|Patents and know-how |  |               | 4,908  |                          |   | (1,788  | )   |  |          | 3,120  |                          |   | 4,904  |     |   | (1,578 | ) |  |   | 3,326 
|                     |  |               |        |                          |   |         |     |  |          |        |                          |   |        |     |   |        |   |  |   |       
|Totals               |  | $             | 20,609 |                          | $ | (10,061 | )   |  | $        | 10,548 |                          | $ | 20,478 |     | $ | (9,120 | ) |  | $ | 11,358
|                     |  |               |        |                          |   |         |     |  |          |        |                          |   |        |     |   |        |   |  |   |       

---

|(1) | Cost reflects the cumulative historical effect of foreign currency translation on intangible assets acquired in a prior business combination. This cumulative historical effect of
foreign currency translation amounted to approximately $0.5 million and $0.4 million as of June 30, 2006 and December 31, 2005, respectively.
|--- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

(7) Accrued Expenses and Other Current Liabilities

Accrued expenses and other current liabilities
are comprised of the following at June 30, 2006 and December 31, 2005 (in thousands):



|                                        |  |               |       |                   |   |      
|--------------------------------------- |  | ------------- | ----- | ----------------- | - | -----
|                                        |  | June 30, 2006 |       | December 31, 2005
|Employee compensation                   |  | $             | 716   |                   | $ | 1,930
|Current portion of patent obligations   |  |               | 150   |                   |   | 150  
|Royalties on licensed technology        |  |               | 113   |                   |   | 362  
|Restructuring                           |  |               | 788   |                   |   | 542  
|Professional fees                       |  |               | 1,576 |                   |   | 2,055
|VAT and other taxes                     |  |               | 2,117 |                   |   | 2,665
|Current portion of guarantee obligation |  |               | 283   |                   |   | 283  
|Other                                   |  |               | 936   |                   |   | 1,090
|                                        |  |               |       |                   |   |      
|                                        |  | $             | 6,679 |                   | $ | 9,077
|                                        |  |               |       |                   |   |      



9



---

##### Table of Contents

ORCHID CELLMARK INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS(Continued)

(Unaudited)



(8) Fixed Assets

Fixed assets are comprised of the following at June 30, 2006 and December 31, 2005 (in thousands):



|                              |  |               |         |   |                   |   |         |  
|----------------------------- |  | ------------- | ------- | - | ----------------- | - | ------- | -
|                              |  | June 30, 2006 |         |   | December 31, 2005 |  
|Laboratory equipment          |  | $             | 16,533  |   |                   | $ | 16,013  |  
|Computers and software        |  |               | 5,058   |   |                   |   | 4,893   |  
|Furniture and fixtures        |  |               | 1,582   |   |                   |   | 1,083   |  
|Leasehold improvements        |  |               | 5,429   |   |                   |   | 4,759   |  
|                              |  |               |         |   |                   |   |         |  
|Less accumulated depreciation |  |               | 28,602  |   |                   |   | 26,748  |  
|                              |  |               | (19,763 | ) |                   |   | (17,652 | )
|                              |  |               |         |   |                   |   |         |  
|                              |  | $             | 8,839   |   |                   | $ | 9,096   |  
|                              |  |               |         |   |                   |   |         |  

Depreciation expense for the Companys fixed assets for the six months ended June 30,
2006 and 2005 was $1.8 million and $1.9 million, respectively.

(9) Restructuring

During the six months ended June 30, 2006, the Company recognized $0.5 million in restructuring charges primarily for employee severance costs
resulting from workforce reductions in the Companys Princeton, New Jersey corporate office and for facility obligation costs for the Companys Germantown, Maryland and old Dallas, Texas facilities. During the six months ended
June 30, 2005, the Company recognized $0.5 million in restructuring charges primarily for employee severance costs resulting from workforce reductions in the Princeton, New Jersey corporate office and the Germantown, Maryland facility.

As of June 30, 2006 and December 31, 2005, the Company had $1.0 million and $0.9 million, respectively, in restructuring
accruals outstanding that are related to severance and facility obligations, of which approximately $0.2 million and $0.3 million, respectively, were classified as a long-term liability.

A summary of the restructuring activity is as follows (in thousands):



|                                                      |  |                     |     |   |                |   |      |       |  |   |      |  
|----------------------------------------------------- |  | ------------------- | --- | - | -------------- | - | ---- | ----- |  | - | ---- | -
|                                                      |  | Workforce Reduction |     |   | Facility Costs |   |      | Total | 
|Restructuring liability as of December 31, 2005       |  | $                   | 27  |   |                | $ | 844  |       |  | $ | 871  |  
|Charge recorded in the six months ended June 30, 2006 |  |                     | 421 |   |                |   | 65   |       |  |   | 486  |  
|Cash payments in the six months ended June 30, 2006   |  |                     | (26 | ) |                |   | (378 | )     |  |   | (404 | )
|                                                      |  |                     |     |   |                |   |      |       |  |   |      |  
|Restructuring liability as of June 30, 2006           |  | $                   | 422 |   |                | $ | 531  |       |  | $ | 953  |  
|                                                      |  |                     |     |   |                |   |      |       |  |   |      |  

(10) Guarantee of Tepnel lease

In connection with the sale of assets and liabilities of the Companys Diagnostics business to Tepnel Life Sciences, PLC (Tepnel), the Company was
required to sign an unconditional guarantee related to the lease for the Stamford, Connecticut based laboratory, which was assigned to Tepnel. The Company reflected the fair value of the guarantee of $1.6 million at the time of the sale of the
Diagnostics business as a reduction to the net realizable value of these assets and liabilities. The fair value of the guarantee was approximately $1.3 million and $1.4 million as of June 30, 2006 and December 31, 2005, respectively, of
which approximately $1.0 million and $1.1 million, respectively, is included in other long-term liabilities in the consolidated balance sheet. The Company included approximately $0.1 million of income in other income (expense) for the six months
ended June 30, 2006, which represents the change in the fair value of the outstanding liability. The Company valued the guarantee based on the existing terms and conditions of the lease, an estimated vacancy of the space for one year prior to
subleasing the space and the expected rental income from the sublease of the space. The lease terminates in April of 2010. Minimum remaining rents under the assigned lease totaled approximately $2.2 million as of June 30, 2006.



10



---

##### Table of Contents

ORCHID CELLMARK INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS(Continued)

(Unaudited)



(11) Accumulated Other Comprehensive Income

The accumulated balances for each classification of items within accumulated other comprehensive income are as follows (in thousands):



|                                                                                                            |  |                              |       |                                         |   |      |                                        |  |   |      
|----------------------------------------------------------------------------------------------------------- |  | ---------------------------- | ----- | --------------------------------------- | - | ---- | -------------------------------------- |  | - | -----
|                                                                                                            |  | Foreign currency translation |       | Unrealized gains (losses)
on securities |   |      | Accumulated other comprehensive income
|Balance at January 1, 2006                                                                                  |  | $                            | 1,500 |                                         | $ | (260 | )                                      |  | $ | 1,240
|Foreign currency translation adjustment                                                                     |  |                              | 944   |                                         |   |     |                                        |  |   | 944  
|Unrealized holding gain on available-for-sale securities                                                    |  |                              |      |                                         |   | 21   |                                        |  |   | 21   
|Reclassification adjustment for impairment charge on available-for-sale securities included in net loss (1) |  |                              |      |                                         |   | 259  |                                        |  |   | 259  
|                                                                                                            |  |                              |       |                                         |   |      |                                        |  |   |      
|Balance at June 30, 2006                                                                                    |  | $                            | 2,444 |                                         | $ | 20   |                                        |  | $ | 2,464
|                                                                                                            |  |                              |       |                                         |   |      |                                        |  |   |      

---

|(1) | The Company has performed an evaluation to determine whether its investment in certain available-for-sale securities is other-than-temporarily impaired, based upon the
Companys ability and intent to hold for a reasonable period of time sufficient for a forecasted recovery of fair value as of March 31, 2006. As a result of this evaluation and the absence of sufficient evidence to support a recovery of
fair value within a reasonable period of time, the Company considered the investment in the available-for-sale securities to be other-than-temporarily impaired and has recorded an impairment loss of approximately $0.3 million related to these
securities for the six months ended June 30, 2006. This impairment loss is included in other income (expense) in the consolidated statement of operations.
|--- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

(12) Penalty on February 2004 Private Placement

On February 27, 2004, the Company issued
approximately 3,158,000 shares of its common stock and four-year warrants to purchase an additional approximately 632,000 shares of the Companys common stock in a private placement to 33 investors. The per share purchase price for the shares
of common stock was $9.60 and the warrants have a per share exercise price of $13.20. Pursuant to the terms of the securities purchase agreement for the financing, the Company registered the shares of common stock issued in the financing and the
shares of common stock issuable upon exercise of the warrants on a registration statement on Form S-3, which was initially declared effective by the SEC on May 28, 2004. Pursuant to the terms of the securities purchase agreement, the Company
must use its best efforts to keep the registration statement continuously effective for a period of five years or until all shares registered thereon have been sold. In addition, the securities purchase agreement provides that the Company may be
obligated to pay penalties to the investors if the investors are not permitted to sell their shares of common stock received in the financing or upon exercise of the warrants under the registration statement for five or more trading days, whether or
not consecutive. As a result of the Companys failure to file its Annual Report on Form 10-K for the year ended December 31, 2005 and its Quarterly Report on Form 10-Q for the quarter ended March 31, 2006 by their filing deadlines,
the investors were no longer permitted to sell their shares of common stock received in the financing or upon exercise of the warrants under the registration statement. This penalty is payable as of April 7, 2006 and on each monthly anniversary
thereof while such shares of common stock are not permitted to be sold under an effective registration statement. The penalty will total 1% of the aggregate purchase price of the shares of common stock issued on February 27, 2004 that remain
unsold by the investors as of April 7, 2006 for the first month and 2% for each additional month thereafter. As of June 30, 2006, the penalty payment that the Company is obligated to pay to the investors was approximately $0.2 million. To
fulfill its obligations under the securities purchase agreement, on July 10, 2006, the Company filed a post-effective amendment to the registration statement to convert it from a registration statement on Form S-3 to a registration statement on
Form S-1, to enable the investors to sell their shares of common stock issued in the financing and upon exercise of the warrants under an effective registration statement. The SEC declared the post-effective amendment effective on July 20,
2006. The penalty payment is included in accrued expenses and other current liabilities in the Companys consolidated balance sheet as of June 30, 2006.

(13) Landlord Lease Incentives

In August 2005, the Company entered into a lease agreement with the landlord which specified
terms for the design and construction of tenant improvements for the Companys Dallas, Texas facility. As an incentive for the Company to enter into the lease agreement, the landlord agreed to contribute up to approximately $0.4 million towards
tenant improvements. The



11



---

##### Table of Contents

ORCHID CELLMARK INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS(Continued)

(Unaudited)



Company recorded the full cost of the Dallas, Texas facility tenant
improvements as an asset and the landlord incentive as deferred rent (current portion classified as accrued expenses and other current liabilities and the long-term portion classified as other liabilities in the consolidated balance sheets) in
accordance with FASB Technical Bulletin 88-1 Issues Related to Accounting for Leases,or FTB 88-1. Amortization of the deferred rent will be recorded as a reduction of rent expense over the remaining lease term and will be classified as
an operating activity in the consolidated statement of cash flows.

In November 2005, the Company entered into a lease amendment with the
landlord which specified terms for the renovation of the Companys Princeton, New Jersey corporate headquarters. As an incentive for the Company to enter into the lease amendment, the landlord agreed to contribute up to approximately $0.1
million towards tenant improvement costs. The Company recorded the full cost of the Princeton, New Jersey renovation project as an asset and the landlord incentive as deferred rent (current portion classified as accrued expenses and other current
liabilities and the long-term portion classified as other liabilities in the consolidated balance sheets) in accordance with FTB 88-1. Amortization of the deferred rent will be recorded as a reduction of rent expense over the remaining lease
term and will be classified as an operating activity in the consolidated statement of cash flows.

(14) Legal Proceedings

On or about November 21, 2001, a complaint was filed in the United States District Court for the Southern District of New York naming the Company as
a defendant, along with certain of its former officers and underwriters. An amended complaint was filed on April 19, 2002. The complaint, as amended, purportedly was filed on behalf of persons purchasing the Companys stock between
May 4, 2000 and December 6, 2000, and alleges violations of Sections 11, 12(a)(2) and 15 of the Securities Act of 1933, as amended, and Sections 10(b) and 20(a) of the Securities Exchange Act of 1934, as amended, and Rule 10b-5 promulgated
thereunder. The amended complaint alleges that, in connection with the Companys May 5, 2000 initial public offering (IPO), the defendants failed to disclose additional and excessive commissions purportedly solicited by and paid to the
underwriter defendants in exchange for allocating shares of the Companys stock to preferred customers and alleged agreements among the underwriter defendants and preferred customers tying the allocation of IPO shares to agreements to make
additional aftermarket purchases at pre-determined prices. Plaintiffs claim that the failure to disclose these alleged arrangements made the Companys registration statement on Form S-1 filed with the SEC in May 2000 and the prospectus, a part
of the registration statement, materially false and misleading. Plaintiffs seek unspecified damages. The Company believes that the allegations are without merit and has, and intends to continue to, vigorously defend itself against plaintiffs
claims. In this regard, on or about July 15, 2002, the Company filed a motion to dismiss all of the claims against it and its former officers. On October 9, 2002, the court dismissed without prejudice only the Companys former
officers, Dale R. Pfost and Donald R. Marvin, from the litigation in exchange for the Company entering into a tolling agreement with plaintiffs executive committee. On February 19, 2003, the Company received notice of the courts
decision to dismiss the Section 10(b) claims against the Company. Plaintiffs and the defendant issuers involved in this IPO securities litigation, including the Company, have agreed in principal on a settlement that, upon a one-time surety
payment by the defendant issuers insurers, would release the defendant issuers and their individual officers and directors from claims and any future payments or out-of-pocket costs. On March 10, 2005, the court issued a memorandum and
order (i) preliminarily approving the settlement, contingent on the parties agreement on modifications of the proposed bar order in the settlement documents, (ii) certifying the parties proposed settlement classes,
(iii) certifying the proposed class representatives for the purposes of the settlement only, and (iv) setting a further hearing for the purposes of (a) making a final determination as to the form, substance, and program of notice of
proposed settlement and (b) scheduling a public fairness hearing in order to determine whether the settlement can be finally approved by the court. On April 24, 2006, the court held a fairness hearing but did not rule on the motion for
final approval of the settlement.

The Company is a defendant in litigation pending in the Southern District of New York entitled Enzo
Biochem, Inc. et al. v. Amersham PLC, et al, filed in October 2002. By their complaint, plaintiffs allege that certain defendants (i) breached their distributorship agreements by selling certain products for commercial development (which they
allege was not authorized), (ii) infringed plaintiffs patents through the sale and use of certain products, and (iii) are liable for fraud, unfair competition and tortious interference with contractual relations. The Company did not
have a contractual relationship with plaintiffs, but is alleged to have purchased the product at issue from one of the other defendants. The Company has sold the business unit that was allegedly engaged in the unlawful conduct. As a result, there is
no relevant injunctive relief to be sought from the Company. The complaint seeks damages in an undisclosed amount. Most of the fact discovery in the case has been taken, and a Markman hearing to construe the patent claims was conducted in early July
2005. On July 17, 2006, the Court ruled in the Companys favor on its construction of the patents asserted against the Company, and the co-defendants, including the Company, plan to move for summary judgment in the fall of 2006.



12



---

##### Table of Contents

ORCHID CELLMARK INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS(Continued)

(Unaudited)



Additionally, the Company has certain other claims against
it arising from the normal course of its business. The ultimate resolution of such matters, including those cases disclosed above, in the opinion of management, will not have a material effect on the Companys financial position, but could have
a material impact on the Companys results of operations for any reporting period.



13



---

##### Table of Contents

Item 2. MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

This
Managements Discussion and Analysis of Financial Condition and Results of Operations as of June 30, 2006 and for the three and six months ended June 30, 2006 and 2005 should be read in conjunction with our Consolidated Financial
Statements and related Notes to Consolidated Financial Statements included elsewhere in this Quarterly Report on Form 10-Q.

OVERVIEW

We are engaged in the provision of DNA testing services that generate genetic profile information by analyzing an organisms unique genetic identity.
We focus our business on DNA testing for human identity as well as for animal and agricultural applications. In the human identity area, we provide DNA testing services for forensic, family relationship and security applications. Forensic DNA
testing is primarily used to establish or maintain databases of individuals convicted of crimes or, in some instances, arrested in connection with crimes, confirm that a suspect committed a particular crime or to exonerate an innocent person. Family
relationship DNA testing is used to establish whether two or more people are genetically related. Recently, DNA testing has been used by individuals and employers in security applications by seeking to establish a persons genetic identity and
store it for identification purposes in the event of an emergency or accident. In the animal and agriculture field, we provide DNA testing services for food safety and selective trait breeding. Our services are used extensively in these
applications, and we expect the use of our services to increase as these markets continue to grow and new commercial applications evolve. We have operations in the United States, or US, and in the United Kingdom, or UK. We market our services in
many countries primarily in North America and Europe; however, the majority of our current customers are based in the US and in the UK.

For the six months ended June 30, 2006, our cash and cash equivalents decreased by approximately $11.7 million to approximately $11.5 million as of June 30, 2006 from approximately $23.2 million as of December 31, 2005 and
our working capital decreased by approximately $7.7 million to approximately $15.1 million at June 30, 2006 from approximately $22.8 million at December 31, 2005. This decrease in working capital was primarily a result of the net loss for
the six months ended June 30, 2006.

Our cash and cash equivalents declined by $8.3 million during the three months ended
June 30, 2006. We believe that the substantial decline in our cash and cash equivalents during this period is not indicative of our quarterly cash needs going forward.

We believe that our existing cash and cash equivalents will be sufficient to sustain our operations at least through the next twelve months; however, we
expect to need additional cash as our turnaround continues and we seek to grow the company.

We perform forensic testing services for
several police forces throughout the UK through our agreement with Forensic Alliance Ltd., or FAL. Revenues derived through the FAL agreement accounted for approximately 23% and 31% of our total revenues for the three months ended June 30, 2006
and 2005, respectively, and approximately 25% and 30% of our total revenues for the six months ended June 30, 2006 and 2005, respectively. Revenues derived through the FAL agreement accounted for approximately 51% and 65% of our UK
revenues for the three months ended June 30, 2006 and 2005, respectively, and approximately 56% and 66% of our UK revenues for the six months ended June 30, 2006 and 2005, respectively. In 2005, FAL was acquired by LGC Ltd., or, LGC, a
provider of analytical and diagnostic services, including DNA testing services, and to that extent is in a position to compete for the business we currently conduct for FAL. On July 7, 2006, we received from FAL notice of termination of this
agreement, effective July 15, 2007. We have been and are implementing plans to enable us to directly provide our services to UK police forces and extend our offerings of forensic services. As a result of our receipt of the notice of
termination, we are in discussions with LGC regarding the transitioning of services we provide to UK police forces, including addressing the provision of services to police forces whose contract with FAL extends beyond the termination of our
contract with FAL.

Operating Highlights

Our revenues are predominately generated from DNA testing services provided to our customers. Our costs and expenses consist of costs of service revenues, research and development expenses, marketing and sales expenses, general and
administrative expenses and other income and expense. Costs of service revenues consist primarily of salaries and related personnel costs, laboratory supplies, fees paid for the collection of samples and facility expenses. Research and development
expenses consist primarily of salaries and related costs, fees paid to consultants and outside service providers for development, laboratory supplies and other expenses related to the design, development, testing and enhancement of our services.
Marketing and sales expenses consist of salaries and benefits for salespeople within our organization and all related costs of selling and marketing our products and services. General and administrative expenses consist primarily of salaries and
related expenses for executive, finance and administrative personnel, professional fees and other corporate expenses.



14



---

##### Table of Contents

Our operating results declined for the three and six months ended June 30, 2006, as compared to the
same period in 2005. Overall, for the three months ended June 30, 2006 as compared to the three months ended June 30, 2005, total revenues decreased approximately 14% and gross margin decreased to approximately 27% from approximately 43%
in the prior year comparable period. The decline in revenues and gross margin was primarily a result of the following factors during the three months ended June 30, 2006 as compared to 2005: declines in pricing for our US forensic casework and
US government paternity testing services and some of our UK Police and Criminal Evidence Act, or PACE, database testing services; lower testing volume in our US government paternity testing services and our UK non-violent crime testing services; and
increased average cost per sample for our testing services involving DNA profile uploads into the Federal Bureau of Investigations Combined DNA Index System, or CODIS, and certain similar state databases. The decline in revenues and gross
margin was partly offset by increased volume for UK contracted government paternity testing services and US CODIS and certain similar state databases testing services. For the three months ended June 30, 2006, our operating expenses other than
cost of service revenues declined by approximately 4% as compared to the same period in 2005, primarily as a result of decreased research and development, marketing and sales and general and administrative expenses, due to our focus on cost
containment.

Overall, for the six months ended June 30, 2006 as compared to the six months ended June 30, 2005, total revenues
decreased approximately 14% and gross margin decreased to approximately 23% from approximately 41% in the prior year comparable period. The decline in revenues and gross margin was primarily a result of the following factors during the six months
ended June 30, 2006 as compared to the prior year comparable period: declines in pricing for our US forensic casework testing services and US government paternity testing services and some of our UK PACE database testing services; lower testing
volume in our US forensic casework and US government paternity testing services and our UK non-violent crime and UK agricultural testing services; and increased average cost per sample for our US testing services involving DNA profile uploads into
CODIS and certain similar state databases. The decline in revenues and gross margin was partly offset by increased volume for US private paternity testing services, UK contracted government paternity testing services and US CODIS and certain similar
state databases testing services. For the six months ended June 30, 2006, our operating expenses other than cost of service revenues increased by approximately 7% as compared to the same period in 2005, primarily as a result of increased
marketing and sales and general and administrative expenses. Marketing and sales expenses increased primarily due to increased radio advertising expense and increased field sales personnel headcount and general and administrative expenses increased
primarily due to higher consulting costs, professional fees and stock-based compensation expense.

RESULTS OF OPERATIONS

The following table sets forth a quarter-over-quarter comparison of the components of our net loss for the three months ended June 30, 2006 and 2005:



|                                  |  |                |        |   |            |   |        |          |  |   |        |   |  |      |   
|--------------------------------- |  | -------------- | ------ | - | ---------- | - | ------ | -------- |  | - | ------ | - |  | ---- | --
|                                  |  | (In thousands) |        |   | % Change   |  
|                                  |  | 2006           |        |   | 2005       |   |        | $ Change |  |  
|                                  |  |                |        |   | (Restated) |   |        |          |  |   |        |  
|Total revenues                    |  | $              | 13,613 |   |            | $ | 15,837 |          |  | $ | (2,224 | ) |  | (14  | )%
|Cost of service revenues          |  |                | 9,919  |   |            |   | 9,042  |          |  |   | 877    |   |  | 10   |   
|Research and development          |  |                | 316    |   |            |   | 417    |          |  |   | (101   | ) |  | (24  | ) 
|Marketing and sales               |  |                | 1,750  |   |            |   | 1,947  |          |  |   | (197   | ) |  | (10  | ) 
|General and administrative        |  |                | 4,778  |   |            |   | 4,912  |          |  |   | (134   | ) |  | (3   | ) 
|Restructuring                     |  |                | 432    |   |            |   | 358    |          |  |   | 74     |   |  | 21   |   
|Amortization of intangible assets |  |                | 441    |   |            |   | 430    |          |  |   | 11     |   |  | 3    |   
|Other income (expense), net       |  |                | 3      |   |            |   | 1,703  |          |  |   | (1,700 | ) |  | (100 | ) 
|Income tax expense                |  |                | 210    |   |            |   | 616    |          |  |   | (406   | ) |  | (66  | ) 
|Net loss                          |  |                | (4,230 | ) |            |   | (182   | )        |  |   | (4,048 | ) |  | >100 |   

Revenues

Total revenues for the three months ended June 30, 2006 of approximately $13.6 million represented a decrease of approximately $2.2 million, or approximately 14%, as compared to revenues of approximately $15.8
million for the comparable period of 2005. Revenues from our service businesses of forensic, family relationship and animal and agricultural DNA testing for the three months ended June 30, 2006 were approximately $13.5 million, as compared to
approximately $15.7 million for the three months ended June 30, 2005.



15



---

##### Table of Contents

Our US service revenues for the three months ended June 30, 2006 of approximately $7.3 million
declined by approximately $1.0 million, or approximately 12%, as compared to approximately $8.3 million for the comparable period of 2005, primarily due to declines in pricing for our forensic casework and government paternity testing
services This decline was slightly offset by increased volume for our CODIS and certain similar state databases testing services. We are experiencing severe pricing pressure in our government funded paternity services as the Federal government
will reduce its matching funding to the states from 90% to 66% effective October 1, 2006.

Revenues from our UK based testing services
declined by approximately $1.2 million, or 16%, to approximately $6.2 million during the three months ended June 30, 2006, as compared to approximately $7.4 million during the comparable period of the prior year. Specifically, the forensic
testing services declined due to reduced volume in non-violent crime testing services and declines in pricing for some of our PACE database testing services, with such declines offset slightly by increased paternity testing due to increased volume.
For the three months ended June 30, 2006, as compared to the same period in 2005, our UK revenues were unfavorably impacted by approximately 2%, as a result of the exchange rate movement of the British Pound as compared to the US dollar.

Our operations in the UK provided all of our animal and agricultural testing services, in addition to a portion of our forensic and
paternity DNA testing services, and accounted for approximately 46% and 47% of our total revenues for the three months ended June 30, 2006 and 2005, respectively. For the three months ended June 30, 2006 and 2005, approximately 67% and
80%, respectively, of our UK revenues were derived through agreements with two contractors, Department for Environment, Food and Rural Affairs, or DEFRA, and FAL.

In May 2006, the DEFRA contract was extended through December 2006. We expect DEFRA to put the contract out for bid and we intend to bid for the ability to continue to perform scrapie testing for DEFRA.

We perform forensic testing services for several police forces throughout the UK through our agreement with FAL. Revenues derived through the FAL
agreement accounted for approximately 23% and 31% of our total revenues and approximately 51% and 65% of our UK revenues for the three months ended June 30, 2006 and 2005, respectively. In 2005, FAL was acquired by LGC, a provider of analytical
and diagnostic services, including DNA testing services, and to that extent is in a position to compete for the business we currently conduct for FAL. On July 7, 2006, we received from FAL notice of termination of this agreement, effective
July 15, 2007. We have been and are implementing plans to enable us to directly provide our services to UK police forces and extend our offerings of forensic services. As a result of our receipt of the notice of termination, we are in
discussions with LGC regarding the transitioning of services we provide to UK police forces, including addressing the provision of services to police forces whose contract with FAL extends beyond the termination of our contract with FAL. We continue
to expect our UK operations to be a significant part of our business.

During each of the three months ended June 30, 2006 and 2005,
we recognized approximately $0.1 million in other revenues, specifically license and grant revenues.

Cost of Service Revenues

Cost of service revenues were approximately $9.9 million, or approximately 73% of revenues, for the three months ended June 30, 2006, compared to
approximately $9.0 million, or approximately 57% of revenues, for the comparable period of the prior year. The increase in cost of service revenues and cost of service revenues as a percentage of revenues primarily reflects declines in pricing for
our US forensic casework testing services, US government paternity testing services and some of our UK PACE database testing services; increased average cost per sample in our CODIS and certain similar state databases testing services; and decreased
volume in our UK non-violent crime testing services.

Research and Development

Research and development expenses for the three months ended June 30, 2006 were approximately $0.3 million, a decrease of approximately $0.1 million
from approximately $0.4 million for the comparable period of the prior year, primarily as a result of spending reductions following the closure of our Germantown, Maryland facility.

Marketing and Sales

Marketing and sales expenses for the three months ended June 30,
2006 were approximately $1.7 million, as compared to approximately $1.9 million during the comparable period of the prior year. The decrease in marketing and sales expenses of approximately $0.2 million was primarily due to decreased spending in
radio advertising related to our marketing and sales programs in our private paternity testing business. The radio advertising campaign was initiated in the second quarter of 2005; we discontinued the campaign in the second quarter of 2006.



16



---

##### Table of Contents

General and Administrative

General and administrative expenses for the three months ended June 30, 2006 were approximately $4.8 million, a decrease of approximately $0.1 million, as compared to approximately $4.9 million for the comparable
period of the prior year. The decrease in general and administrative expenses in the second quarter of 2006 included decreases in salaries, rent, software licenses, professional fees other than legal and audit expenses and franchise taxes. The
decreases were partially offset by increases in professional fees for audit and legal expenses, consulting expenses and in general and administrative stock-based compensation recorded in accordance with Statement of Financial Accounting Standards,
or SFAS, No. 123(R), Share-Based Payment, or SFAS 123(R).

Restructuring

Restructuring expenses for each of the three months ended June 30, 2006 and 2005 were approximately $0.4 million. The restructuring costs in 2006
primarily consisted of employee severance costs resulting from workforce reductions in our Princeton, New Jersey corporate office and for facility obligation costs for the Companys Germantown, Maryland and old Dallas, Texas facilities. The
restructuring costs in 2005 were primarily for employee severance costs related to workforce reductions in our corporate office and the Germantown, Maryland facility.

Amortization of Intangible Assets

During each of the three months ended June 30, 2006
and 2005, we recorded approximately $0.4 million of amortization of intangible assets.

Other Income (Expense), Net

Interest income for the three months ended June 30, 2006 was approximately $0.2 million, compared to approximately $0.1 million during the same
period of the prior year. This increase was primarily due to increased interest rates in 2006 as compared to 2005.

Total other expense for
the three months ended June 30, 2006 was approximately $0.2 million, which primarily consisted of an accrual of a penalty payment associated with our February 2004 private placement equity offering. Total other income for the three months ended
June 30, 2005 was approximately $1.6 million, which primarily consisted of a non-cash gain on the acquisition of treasury stock in connection with the settlement of escrow claims and the return of treasury shares associated with our December
2001 acquisition of Lifecodes Corporation, or Lifecodes.

Income Tax Expense

During the three months ended June 30, 2006 and 2005, we recorded net income tax expense related to our profitable UK business of approximately $0.2
million and approximately $0.6 million, respectively.

The following table sets forth a comparison of the components of our net loss for the six
months ended June 30, 2006 and 2005:



|                                  |  |                |         |   |            |   |        |          |  |   |          |   |  |       |   
|--------------------------------- |  | -------------- | ------- | - | ---------- | - | ------ | -------- |  | - | -------- | - |  | ----- | --
|                                  |  | (In thousands) |         |   |            |  
|                                  |  | 2006           |         |   | 2005       |   |        | $ Change |  |   | % Change |  
|                                  |  |                |         |   | (Restated) |   |        |          |  |   |          |  
|Total revenues                    |  | $              | 26,208  |   |            | $ | 30,502 |          |  | $ | (4,294   | ) |  | (14   | )%
|Costs of service revenues         |  |                | 20,123  |   |            |   | 18,066 |          |  |   | 2,057    |   |  | 11    |   
|Research and development          |  |                | 594     |   |            |   | 814    |          |  |   | (220     | ) |  | (27   | ) 
|Marketing and sales               |  |                | 3,965   |   |            |   | 3,725  |          |  |   | 240      |   |  | 6     |   
|General and administrative        |  |                | 10,593  |   |            |   | 9,551  |          |  |   | 1,042    |   |  | 11    |   
|Restructuring                     |  |                | 486     |   |            |   | 477    |          |  |   | 11       |   |  | 2     |   
|Amortization of intangible assets |  |                | 880     |   |            |   | 861    |          |  |   | 19       |   |  | 2     |   
|Other income (expense), net       |  |                | (15     | ) |            |   | 1,793  |          |  |   | (1,808   | ) |  | >(100 | ) 
|Income tax expense                |  |                | 381     |   |            |   | 635    |          |  |   | (254     | ) |  | (40   | ) 
|Net loss                          |  |                | (10,829 | ) |            |   | (1,834 | )        |  |   | (8,995   | ) |  | >100  |   



17



---

##### Table of Contents

Revenues

Total revenues for the six months ended June 30, 2006 of approximately $26.2 million represented a decrease of approximately $4.3 million, or approximately 14%, as compared to revenues of approximately $30.5
million for the comparable period of 2005. Revenues from our service businesses of forensic, family relationship and animal and agricultural DNA testing for the six months ended June 30, 2006 were approximately $26.0 million, as compared to
approximately $30.2 million for the six months ended June 30, 2005.

Our US service revenues for the six months ended June 30,
2006 of approximately $14.4 million declined by approximately $1.9 million, or approximately 11%, as compared to approximately $16.3 million for the comparable period of 2005, primarily due to declines in pricing and volume for our forensic casework
and government paternity testing services. This decline was slightly offset by increased volume for our private paternity testing and our CODIS and certain similar state databases testing services. We are experiencing severe pricing pressure in
our government funded paternity services as the Federal government will reduce its matching funding to the states from 90% to 66% effective October 1, 2006.

Revenues from our UK based testing services declined by approximately $2.3 million, or approximately 17%, to approximately $11.6 million during the six months ended June 30, 2006, as compared to approximately
$13.9 million during the comparable period of the prior year. Specifically, the forensic testing services declined due to reduced volume in non-violent crime testing services, declines in pricing for some of our PACE database testing services and
declines in our agricultural testing services due to lower scrapie testing volume, with such declines offset slightly by increased paternity testing due to increased volume. For the six months ended June 30, 2006, as compared to the same period
in 2005, our UK revenues were unfavorably impacted by approximately 5%, as a result of the exchange rate movement of the British Pound as compared to the US dollar.

Our operations in the UK provided all of our animal and agricultural testing services, in addition to a portion of our forensic and paternity DNA testing services, and accounted for approximately 44% and 46% of our
total revenues for the six months ended June 30, 2006 and 2005, respectively. For the six months ended June 30, 2006 and 2005, approximately 68% and 78%, respectively, of our UK revenues were derived through agreements with two
contractors, DEFRA and FAL.

In May 2006, the DEFRA contract was extended through December 2006. We expect DEFRA to put the contract out
for bid and we intend to bid for the ability to continue to perform scrapie testing for DEFRA.

We perform forensic testing services for
several police forces throughout the UK through our agreement with FAL. Revenues derived through the FAL agreement accounted for approximately 25% and 30% of our total revenues and approximately 56% and 66% of our UK revenues for the six months
ended June 30, 2006 and 2005, respectively. In 2005, FAL was acquired by LGC, a provider of analytical and diagnostic services, including DNA testing services, and to that extent is in a position to compete for the business we currently conduct
for FAL. On July 7, 2006, we received from FAL notice of termination of this agreement, effective July 15, 2007. We have been and are implementing plans to enable us to directly provide our services to UK police forces and extend our
offerings of forensic services. As a result of our receipt of the notice of termination, we are in discussions with LGC regarding the transitioning of services we provide to UK police forces, including addressing the provision of services to police
forces whose contract with FAL extends beyond the termination of our contract with FAL. We continue to expect our UK operations to be a significant part of our business.

During the six months ended June 30, 2006, we recognized approximately $0.2 million in other revenues, specifically license and grant revenues, as compared to approximately $0.3 million during the comparable
period in 2005.

Cost of Service Revenues and Gross Margin

Cost of service revenues were approximately $20.1 million, or approximately 77% of revenues, for the six months ended June 30, 2006, compared to approximately $18.1 million, or approximately 59% of revenues, for
the comparable period of the prior year. The increase in cost of service revenues and cost of service revenues as a percentage of revenues primarily reflects declines in pricing for our US forensic casework testing services, US government paternity
testing services and some of our UK PACE database testing services; increased average cost per sample in our CODIS and certain similar state databases testing services; and decreased volume in our UK non-violent crime and UK agricultural testing
services.

Research and Development Expenses

Research and development expenses for the six months ended June 30, 2006 were approximately $0.6 million, a decrease of approximately $0.2 million from approximately $0.8 million for the comparable period of the
prior year, primarily as a result of spending reductions following the closure of our Germantown, Maryland facility.



18



---

##### Table of Contents

Marketing and Sales

Marketing and sales expenses for the six months ended June 30, 2006 were approximately $4.0 million, as compared to approximately $3.7 million during the comparable period of the prior year. The increase in
marketing and sales expenses of approximately $0.3 million was primarily due to increased spending in radio advertising related to our marketing and sales programs in our private paternity testing business and increased headcount of field sales
personnel. The radio advertising campaign was initiated in the second quarter of 2005; we discontinued the campaign in the second quarter of 2006.

General and Administrative

General and administrative expenses for the six months ended June 30, 2006 were
approximately $10.6 million, an increase of approximately $1.0 million, as compared to approximately $9.6 million for the comparable period of the prior year. The increase in general and administrative expenses for the six months ended June 30,
2006 included increases in consulting expenses, professional fees for audit and legal expenses, and general and administrative stock-based compensation recorded in accordance with SFAS 123(R). The increases were partially offset by decreases in
rent, software licenses, depreciation and salaries.

Restructuring

Restructuring expenses for each of the six months ended June 30, 2006 and 2005 were approximately $0.5 million. The restructuring costs in 2006
primarily consisted of employee severance costs resulting from workforce reductions in our Princeton, New Jersey corporate office and for facility obligation costs for our Germantown, Maryland and old Dallas, Texas facilities. The restructuring
costs in 2005 were primarily for employee severance costs related to workforce reductions in our corporate office and the Germantown, Maryland facility, as well as other charges related to the closure of the Germantown, Maryland facility.

Amortization of Intangible Assets

During each of the six months ended June 30, 2006 and 2005, we recorded approximately $0.9 million of amortization of intangible assets.

Other Income (Expense), Net

Interest income for the six months ended June 30, 2006 was approximately $0.3
million, compared to approximately $0.2 million during the same period of the prior year. This increase was primarily due to increased interest rates in 2006 as compared to 2005.

Total other expense for the six months ended June 30, 2006 was approximately $0.3 million, which primarily consisted of an accrual of a penalty
payment associated with our February 2004 private placement equity offering and an impairment charge on available-for-sale securities that were determined to be other-than-temporarily impaired. Total other income for the six months ended
June 30, 2005 was approximately $1.6 million, which primarily consisted of a non-cash gain on the acquisition of treasury stock in connection with the settlement of escrow claims and the return of treasury shares associated with our December
2001 acquisition of Lifecodes.

Income Tax Expense

During the six months ended June 30, 2006 and 2005, we recorded net income tax expense related to our profitable UK business of approximately $0.4 million and approximately $0.6 million, respectively. Income tax
expense for the six months ended June 30, 2005 was net of a tax benefit of approximately $0.5 million related to the reversal of a tax reserve we recorded as a result of the closing of the statute of limitations in January 2005. This benefit
partially offset our income tax expense related to our UK business of approximately $1.1 million.

LIQUIDITY AND CAPITAL RESOURCES

As of June 30, 2006, we had approximately $11.5 million in cash and cash equivalents as compared to approximately $23.2 million as of
December 31, 2005. Working capital decreased to approximately $15.1 million at June 30, 2006 from approximately $22.8 million at December 31, 2005. This decrease in working capital was primarily a result of the net loss for the six
months ended June 30, 2006.



19



---

##### Table of Contents

Our cash and cash equivalents declined by $8.3 million during the three months ended June 30, 2006.
We believe that the substantial decline in our cash and cash equivalents during this period is not indicative of our quarterly cash needs going forward.

We believe that our existing cash and cash equivalents will be sufficient to sustain our operations at least through the next twelve months; however, we expect to need additional cash as our turnaround continues and
we seek to grow the company.

Sources of Liquidity

Our primary sources of liquidity have been capital raising activities and issuances of our securities.

The
following table sets forth a comparison of the components of our liquidity and capital resources for the six months ended June 30, 2006 and 2005:



|                            |  |                |         |   |          |   |        |          |  |   |         |   |  |       |  
|--------------------------- |  | -------------- | ------- | - | -------- | - | ------ | -------- |  | - | ------- | - |  | ----- | -
|                            |  | (In thousands) |         |   | % Change |  
|                            |  | 2006           |         |   | 2005     |   |        | $ Change |  |  
|Cash provided by (used in): |  |                |         |   |          |   |        |          |  |   |         |   |  |       |  
|Operating activities        |  | $              | (11,827 | ) |          | $ | (1,555 | )        |  | $ | (10,272 | ) |  | >100  | %
|Investing activities        |  |                | (534    | ) |          |   | 2,604  |          |  |   | (3,138  | ) |  | >(100 | )
|Financing activities        |  |                | 44      |   |          |   | (23    | )        |  |   | 67      |   |  | >(100 | )

Net cash used in operations for the six months ended June 30, 2006 was approximately $11.8
million compared with net cash used in operations of approximately $1.6 million for the comparable period in the prior year. The decline in operating cash flows was mainly a result of a higher net loss for the six months ended June 30, 2006
than for the comparable period in the prior year, as well as an increase in accounts receivable for the six months ended June 30, 2006, as compared to a decrease in accounts receivable for the comparable period in the prior year. Investing
activities during the six months ended June 30, 2006 included approximately $1.3 million of capital expenditures, partially offset by the release of approximately $0.8 million of restricted cash; as compared to approximately $3.7 million in net
proceeds from the sales of short-term securities, partially offset by approximately $1.1 million in capital expenditures for the comparable period in the prior year. Financing activities during the six months ended June 30, 2006 consisted of
proceeds from the issuance of common stock; as compared to approximately $0.3 million used to repay debt, substantially offset by approximately $0.3 million of proceeds from the issuance of common stock for the comparable period in the prior year.

Penalty on February 2004 Private Placement

On February 27, 2004, we issued approximately 3,158,000 shares of our common stock and four-year warrants to purchase an additional approximately 632,000 shares of our common stock in a private placement to 33 investors. The per share
purchase price for the shares of common stock was $9.60 and the warrants have a per share exercise price of $13.20. Pursuant to the terms of the securities purchase agreement for the financing, we registered the shares of common stock issued in the
financing and the shares of common stock issuable upon exercise of the warrants on a registration statement on Form S-3, which was declared effective by the SEC on May 28, 2004. Pursuant to the terms of the securities purchase agreement, we
must use our best efforts to keep the registration statement continuously effective for a period of five years or until all shares registered thereon have been sold. In addition, the securities purchase agreement provides that we may be obligated to
pay penalties to the investors if the investors are not permitted to sell their shares of common stock received in the financing or upon exercise of the warrants under the registration statement for five or more trading days, whether or not
consecutive. As a result of our failure to file our Annual Report on Form 10-K for the year ended December 31, 2005 and our Quarterly Report on Form 10-Q for the quarter ended March 31, 2006 by their filing deadlines, the investors were no
longer permitted to sell their shares of common stock received in the financing or upon exercise of the warrants under the registration statement. This penalty is payable as of April 7, 2006 and on each monthly anniversary thereof while such
shares of common stock are not permitted to be sold under an effective registration statement. The penalty totaled 1% of the aggregate purchase price of the shares of common stock issued on February 27, 2004 that remained unsold by the
investors as of April 7, 2006 for the first month and 2% for each additional month thereafter. As of June 30, 2006, the penalty payment that we are obligated to pay to the investors was approximately $0.2 million. To fulfill our
obligations under the securities purchase agreement, on July 10, 2006, we filed a post-effective amendment to the registration statement to convert it from a registration statement on Form S-3 to a registration statement on Form S-1, to enable
the investors to sell their shares of common stock issued in the financing and upon exercise of the warrants under an effective registration statement. The SEC declared the post-effective amendment effective on July 20, 2006; thus the total
penalty payment that we are obligated to pay to the investors up through July 20, 2006 is approximately $0.3 million.



20



---

##### Table of Contents

Use of Form S-3

As a result of our failure to file our Annual Report on Form 10-K for the year ended December 31, 2005 and our Quarterly Report on Form 10-Q for the quarter ended March 31, 2006 by their filing deadlines,
our securities cannot be registered on or traded under a registration statement on Form S-3 until we regain compliance with the requirements for the use of that form.

Restricted Cash

As of June 30, 2006, cash restricted under one of our operating leases and one
government contract, in the amount of $1.0 million, is reflected as a long-term asset in the consolidated balance sheet.

Uses of Liquidity in 2006

Throughout 2006, we plan to continue making substantial investments in our business. We expect the following to be significant uses
of liquidity: cost of service revenues, salaries and related personnel costs, laboratory supplies, fees for the collection of samples, facility expenses and general and administrative costs, which consist primarily of salaries and related expenses
for executive, finance and administrative personnel, professional fees, general legal expenses, expenses related to our intellectual property and other corporate expenses. In addition, we may make investments in future acquisitions of businesses or
technologies which would increase our capital expenditures.

The amounts and timing of our actual expenditures will depend upon numerous
factors, including our development activities, our investments in technology, the amount of cash generated by our operations and the amount and extent of our acquisitions, if any. Actual expenditures may vary substantially from our estimates.

Our cash and cash equivalents declined by $8.3 million during the three months ended June 30, 2006. We believe that the substantial
decline in our cash and cash equivalents during this period is not indicative of our quarterly cash needs going forward.

We believe that
our existing cash and cash equivalents will be sufficient to sustain our operations at least through the next twelve months; however, we expect to need additional cash as our turnaround continues and we seek to grow the company. If so, we may not be
able to raise additional funds or raise funds on terms that are acceptable to us, if at all. If future financing is not available to us, or is not available on terms acceptable to us, we may not be able to fund our future needs. If we raise funds
through equity or convertible securities, our stockholders may experience dilution and our stock price may decline.

We cannot be certain
that our business or operations will not consume available resources more rapidly than anticipated. We also cannot be certain that we will not require additional funding beyond amounts currently anticipated before we can achieve profitable
operations. We also may need additional capital if we seek to acquire other businesses or technologies.

As of December 31, 2005, our
net operating loss, or NOL, carryforwards were approximately $234 million and approximately $194 million for Federal and state income tax purposes, respectively. Our Federal and state NOL carryforwards begin to expire in 2006. Utilization of our NOL
carryforwards to offset future taxable income, if any, may be substantially limited due to change of ownership provisions in the Tax Reform Act of 1986, or the Act. The Act provides for a limitation on the annual use of NOL carryforwards
and research and development credits following certain ownership changes, as defined by the Act, which could significantly limit our ability to utilize these carryforwards and research and development credits. We have determined that an ownership
change, as defined by the Act, occurred in 1999. Approximately $36 million of NOL carryforwards is limited due to this ownership change. Additionally, because US tax laws limit the time during which these carryforwards may be applied against future
taxes, we may not be able to take full advantage of these attributes for Federal income tax purposes. The NOL carryforwards subject to expiration through the year 2019 is approximately $32 million. We may have experienced other ownership changes, as
defined by the Act, as a result of past financings and may experience others in connection with future financings. Accordingly, our ability to utilize the aforementioned Federal NOL carryforwards may be further limited in the future.

Critical Accounting Policies

Our critical
accounting policies are as follows:



| |  |  | revenue recognition;
| | - |  | --------------------



| |  |  | stock-based compensation;
| | - |  | -------------------------



21



---

##### Table of Contents

| |  |  | valuation of long-lived and intangible assets and goodwill; and
| | - |  | ---------------------------------------------------------------



| |  |  | income taxes.
| | - |  | -------------

Revenue Recognition

We recognize DNA laboratory services revenues at the time test results are completed and reported. Deferred revenues represent the unearned portion of
payments received in advance of tests being completed and reported. Unbilled receivables represent revenue which has been earned on completed and reported tests, but has not been billed to the customer. Revenues from license arrangements, including
license fees creditable against future royalty obligations of the licensee, are recognized when an arrangement is entered into if we have no significant continuing involvement under the terms of the arrangement. If we have significant continuing
involvement under such an arrangement, license fees are deferred and recognized over the estimated performance period. Management has made estimates and assumptions relating to the performance period, which are subject to change. Changes in these
estimates and assumptions could affect the amount of revenues from licenses reported in any given period. Revenues from research and development agreements are recognized when related research expenses are incurred and when we have satisfied
specific obligations under the terms of the respective agreements.

Stock-based Compensation

Effective January 1, 2006, we adopted the provisions of, and account for stock-based compensation in accordance with, SFAS 123(R). Under the fair
value recognition provisions of this statement, stock-based compensation cost is measured at the grant date based on the fair value of the award and is recognized as expense over the requisite service period, which is the vesting period. We have
applied the modified prospective method of adoption, under which prior periods are not restated for comparative purposes. Under the modified prospective method, SFAS 123(R) applies to new awards and to awards that were outstanding as of
December 31, 2005 that are subsequently modified, repurchased or cancelled. Compensation expense recognized during the six months ended June 30, 2006 includes the expense for all share-based payments granted prior to, but not yet vested as
of, December 31, 2005, based on the grant date fair value estimated in accordance with the original provisions of SFAS No. 123, Accounting for Stock-Based Compensation, and the expense for all share-based payments granted during the
six months ended June 30, 2006, based on the grant-date fair value estimated in accordance with the provisions of SFAS 123(R). Stock-based compensation is classified within cost of service revenues, research and development, marketing and sales
and general and administrative on the consolidated statement of operations.

Stock options granted to employees, which are granted with an
exercise price equal to or greater the fair market value of our common stock at the date of grant, in general vest in four years in equal monthly installments and have a maximum term of ten years. Stock options granted to our Board of Directors in
general vest in three years in equal monthly installments and have a maximum term of ten years.

We use the Black-Scholes option pricing
model to estimate the fair value of options granted, which requires the input of highly subjective assumptions. These assumptions include estimating the risk-free interest rate, the length of time employees will retain their vested stock options
before exercising them, the estimated volatility of our common stock price over the expected term, the number of options that will ultimately not vest and the expected dividend yield. Changes in the subjective assumptions can materially affect the
estimate of the fair value of stock-based compensation and, consequently, the related amount recognized in the consolidated statements of operations. The risk-free interest rate assumption is based upon the US Treasury yields in effect at the time
of grant for periods closest to the expected term of the option. The expected volatility assumption is based on the daily historical volatility of our stock price, over the expected life of the option. Our stock options are considered plain
vanilla options based on the guidance in SEC Staff Accounting Bulletin No. 107, Share-Based Payment, and as such we have elected the use of the simplified method, whereby we have assumed that all options will be
exercised midway between the vesting date and the contractual term of the option to determine the expected term of the option. We have not paid dividends since our inception, nor do we expect to pay any dividends for the foreseeable future, thus the
expected dividend yield assumption is zero. As stock-based compensation expense recognized in the consolidated statement of operations is based on awards ultimately expected to vest, the amount of expense has been reduced for estimated forfeitures.
SFAS 123(R) requires forfeitures to be estimated at the time of grant and revised, if necessary, in subsequent periods if actual forfeitures differ from those estimates. Forfeitures are estimated based on historical experience.

Valuation of Long-Lived and Intangible Assets and Goodwill

We assess the impairment of amortizable identifiable intangibles and long-lived assets whenever events or changes in circumstances indicate that the carrying value may not be recoverable. Factors we consider important which could trigger an
impairment review include the following:



| |  |  | significant underperformance relative to expected historical or projected future operating results;
| | - |  | ---------------------------------------------------------------------------------------------------



22



---

##### Table of Contents

| |  |  | significant changes in the manner of our use of the acquired assets or the strategy for our overall business;
| | - |  | -------------------------------------------------------------------------------------------------------------



| |  |  | significant negative industry or economic trends; and
| | - |  | -----------------------------------------------------



| |  |  | significant decrease in the market value of the assets.
| | - |  | -------------------------------------------------------

When we determine that the carrying value of amortizable intangibles and other long-lived assets may not be recoverable based upon the existence of one or more of the above indicators of impairment, we measure any impairment based on
a projected discounted cash flow method using a discount rate determined by our management to be commensurate with the risk inherent in our current business. Net amortizable intangible assets and long-lived assets amounted to approximately $19.4
million as of June 30, 2006. Goodwill is subject to at least an annual recoverability assessment pursuant to the provisions of SFAS, No. 142 Goodwill and Other Intangible Assets.

Accounting for Income Taxes.

We have generated net
operating losses for tax purposes since inception. As of December 31, 2005, these losses have generated NOL carryforwards of approximately $234 million and $194 million for Federal and state income tax purposes, respectively. In addition,
certain charges recorded in the current and prior years were not currently deductible for income tax purposes. These differences result in gross deferred tax assets. We must assess the likelihood that the gross deferred tax assets, net of any
deferred tax liabilities, will be recovered from future taxable income. To the extent we believe the recovery is not likely, we have established a valuation allowance.

Significant management judgment is required in determining this valuation allowance. We have recorded a valuation allowance of approximately $108 million as of December 31, 2005, due to uncertainties related to
our ability to utilize some of our net deferred tax assets, primarily consisting of certain NOL carryforwards, before they expire. The valuation allowance is based on our estimates of taxable income and the period over which the net deferred tax
assets will be recoverable.

Conversely, if we are profitable in the future at levels which cause management to conclude that it is more
likely than not that we will realize all or a portion of the net deferred tax assets for which a valuation has been recorded, we would record the estimated net realizable value of the net deferred tax asset at that time and would then record income
taxes at a rate equal to our combined federal and state effective rate of approximately 40%.

Recently Issued Accounting Pronouncements

In July 2006, the Financial Accounting Standards Board, or FASB, issued FASB Interpretation 48, Accounting for Uncertainty in
Income Taxes, or FIN 48. The intent of FIN 48 is to clarify the accounting for uncertainty in income taxes recognized in an entitys financial statements in accordance with SFAS No. 109, Accounting for Income Taxes. This
interpretation imposes a recognition threshold and measurement attribute for financial statement disclosure of tax positions taken or expected to be taken on a tax return. This interpretation is effective as of the beginning of the first fiscal year
beginning after December 15, 2006. We will be required to adopt this interpretation in the first quarter of 2007. Management is currently evaluating the requirements of FIN 48 and has not yet determined the impact this adoption will have on the
consolidated financial statements.

Item 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK

Interest Rate Sensitivity

Our exposure to market risk is principally confined to our cash equivalents, which are conservative in nature, with a focus on preservation of capital.
Due to the short-term nature of our investments and the investment policies and procedures, we have determined that the risks associated with interest rate fluctuations related to these financial instruments are not material to our business. As of
June 30, 2006, we have no long-term debt obligations.

Foreign Currency Risk

Our business derives a substantial portion of its sales from UK operations. We record the majority of our foreign operational transactions, including all
cash inflows and outflows, in the local currency, British Pound Sterling. We also record all of our US operational transactions, including cash inflows and outflows in US dollars. We expect that international sales will continue to represent a
significant portion of our revenue. Fluctuations in foreign currencies may have an impact on our reported financial results. The significant percentage of our revenue derived from our UK operations makes us vulnerable to unfavorable fluctuations in
the exchange rate, which would have an unfavorable translation impact on our consolidated financial results. We may hedge against any fluctuations in foreign currencies should such fluctuations have a material economic impact on us, although we have
not engaged in hedging activities to date. There has not been any significant change to the foreign currency sensitivity analysis we performed as of December 31, 2005.



23



---

##### Table of Contents

Item 4. CONTROLS AND PROCEDURES

(a) Evaluation of disclosure controls and procedures. Our
principal executive and financial officers reviewed and evaluated the effectiveness of our disclosure controls and procedures (as defined in Exchange Act Rule 13a-15(e) and 15d-15(e)) as of the end of the period covered by this Quarterly Report on
Form 10-Q. Based on that evaluation, our principal executive and financial officers have concluded that our disclosure controls and procedures were not effective as of the end of the period covered by this Quarterly Report on Form 10-Q because we
have not yet completed the remediation of the material weaknesses discussed under Item 9A Controls and Procedures in our Annual Report on Form 10-K for the year ended December 31, 2005. The material weaknesses were as follows:
(i) we did not have adequate policies and procedures designed to ensure that financial reporting information related to significant, non-routine transactions was properly identified and communicated and (ii) we did not have adequate
policies and procedures designed to ensure that accurate and reliable interim and annual consolidated financial statements were prepared and reviewed on a timely basis.

In 2006, management has made some progress in remediating certain aspects of the material weaknesses reported, specifically in regards to additional disclosure meetings, the routing of non-routine transactions for
review and assessment to both the Corporate Controller and the Chief Executive Officer, conducting an accounting training course for all of our global accounting staff focused on our enhanced accounting policies and procedures to ensure that all
financial close documentation and review requirements are proper and adequate and the hiring of a new Chief Executive Officer who will support improved communication among internal departments. However, other aspects of the reported material
weaknesses are still in the remediation process and appear to continue to constitute material weaknesses.

Procedures were undertaken in
order for management to conclude that reasonable assurance exists regarding the reliability of the consolidated financial statements contained in this filing. Accordingly, management believes that the consolidated financial statements included in
this Quarterly Report on Form 10-Q present fairly, in all material respects, the financial position, results of operations and cash flows for the periods presented.

(b) Changes in internal control over financial reporting. There was no change in our internal control over financial reporting, except as described above, that occurred during the period covered by this
Quarterly Report on Form 10-Q that has materially affected, or is reasonably likely to materially affect, our internal control over financial reporting. However, we continue to implement the measures discussed above and under Item 9A
Controls and Procedures in our Annual Report on Form 10-K for the year ended December 31, 2005 to remediate the material weaknesses in our internal control over financial reporting.

(c) Limitations on the effectiveness of controls. Our management, including our Chief Executive Officer and Principal Financial Officer, does not
expect that our disclosure controls and procedures or our internal control over financial reporting will prevent all error and all fraud. A control system, no matter how well conceived and operated, can provide only reasonable, not absolute,
assurance that the objectives of the control system are met. Further, the design of a control system must reflect the fact that there are resource constraints, and the benefits of controls must be considered relative to their costs. Because of the
inherent limitations in all control systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, within our organization have been detected. These inherent limitations include the
realities that judgments in decision-making can be faulty, and that breakdowns can occur because of simple error or mistake.

Additionally,
controls can be circumvented by the individual acts of some persons, by collusion of two or more people, or by management override of the control. The design of any system of controls also is based in part upon certain assumptions about the
likelihood of future events, and there can be no assurance that any design will succeed in achieving our stated goals under all potential future conditions; over time, controls may become inadequate because of changes in conditions, or the degree of
compliance with the policies or procedures may deteriorate. Because of the inherent limitations in a cost-effective control system, misstatements due to error or fraud may occur and not be detected.

FORWARD-LOOKING STATEMENTS

This
Quarterly Report on Form 10-Q contains forward-looking statements. Such statements are based on managements current expectations and are subject to a number of factors and uncertainties that could cause actual results or outcomes to differ
materially from those described in such forward-looking statements. These statements address or may address the following subjects:



| |  |  | our expectation that we will not pay any dividends in the foreseeable future;
| | - |  | -----------------------------------------------------------------------------



24



---

##### Table of Contents

| |  |  | our expectation of the amount and timing of future revenues, expenses and other items affecting the results of our operations;
| | - |  | ------------------------------------------------------------------------------------------------------------------------------



| |  |  | our expectation that the use of our DNA testing services will grow as new applications evolve in family relationship, forensic, security and animal and agricultural markets;
| | - |  | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | our intention to bid for the ability to continue to perform scrapie testing for DEFRA;
| | - |  | --------------------------------------------------------------------------------------



| |  |  | our belief that we may make investments in future acquisitions of complementary businesses or technologies;
| | - |  | -----------------------------------------------------------------------------------------------------------



| |  |  | our intention to continue to vigorously defend ourselves against plaintiffs claims in litigation relating to our May 5, 2000 IPO;
| | - |  | ----------------------------------------------------------------------------------------------------------------------------------



| |  |  | our expectation that the hearing held in 2005 will determine the interpretation of the claims brought against us in certain breach of patent litigation;
| | - |  | --------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | our plan to move for summary judgment in the above patent litigation in the fall of 2006;
| | - |  | -----------------------------------------------------------------------------------------



| |  |  | our belief that litigation claims arising against us from the normal course of business will not have a material effect on our financial position, but could have a material impact
on our results of operations for any reporting period;
| | - |  | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | our expectation that international sales may continue to represent a significant portion of our revenue;
| | - |  | --------------------------------------------------------------------------------------------------------



| |  |  | our belief that fluctuations in foreign currency exchange rates may have an impact on our reported financial results;
| | - |  | ---------------------------------------------------------------------------------------------------------------------



| |  |  | our belief that that the substantial decline in our cash and cash equivalents during three months ended June 30, 2006 is not indicative of our quarterly cash needs going
forward;
| | - |  | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | our expectation about our significant uses of liquidity;
| | - |  | --------------------------------------------------------



| |  |  | our expectation that our existing cash and cash equivalents will be sufficient to sustain our operations at least through the next twelve months;
| | - |  | -------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | our expectation that we will need additional cash as our turnaround continues and we seek to grow the company;
| | - |  | --------------------------------------------------------------------------------------------------------------



| |  |  | our belief that the adoption of certain recently issued accounting pronouncements will have no impact on our consolidated financial statements; and
| | - |  | ---------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | our expectation that our disclosure controls and procedures or our internal control over financial reporting will not prevent all error and all fraud.
| | - |  | ------------------------------------------------------------------------------------------------------------------------------------------------------

While management makes its best efforts to be accurate in making forward-looking statements, such statements are subject to risks and uncertainties that
could cause actual results to vary materially, including the risks and uncertainties discussed throughout this Quarterly Report on Form 10-Q and the cautionary information set forth under the heading Risk Factors appearing in
Item 1A of Part II of this Quarterly Report on Form 10-Q and more fully discussed under the heading Risk Factors appearing in Item 1A of our Annual Report on Form 10-K for the year ended December 31, 2005. Except as
required by law, we undertake no obligation to publicly update or revise forward-looking statements to reflect events or circumstances after the date of this Quarterly Report on Form 10-Q or to reflect the occurrence of unanticipated events.

PART II  OTHER INFORMATION

Item 1. LEGAL PROCEEDINGS

On or about November 21, 2001, a complaint was filed in the United States
District Court for the Southern District of New York naming us as a defendant, along with certain of our former officers and underwriters. An amended complaint was filed on April 19, 2002. The complaint, as amended, purportedly was filed on
behalf of persons purchasing our stock between May 4, 2000 and December 6, 2000, and alleges violations of Sections 11, 12(a)(2) and 15 of the Securities Act of 1933, as amended, and Sections 10(b) and 20(a) of the Securities Exchange Act
of 1934, as amended, and Rule 10b-5 promulgated thereunder. The amended complaint alleges that, in connection with our May 5, 2000 initial public offering, or IPO, the defendants failed to disclose additional and excessive commissions
purportedly solicited by and paid to the underwriter defendants in exchange for allocating shares of our stock to preferred customers and alleged agreements among the underwriter defendants and preferred customers tying the allocation of IPO shares
to agreements to make additional aftermarket purchases at pre-determined prices. Plaintiffs claim that the failure to disclose these alleged arrangements made our registration statement on Form S-1 filed with the SEC in May 2000 and the prospectus,
a part of the registration statement, materially false and misleading. Plaintiffs seek unspecified damages. We believe that the allegations are without merit and have, and intend to continue to, vigorously defend ourselves against plaintiffs
claims. In this regard, on or about July 15, 2002, we filed a motion to dismiss all of the claims against us and our former officers. On October 9, 2002, the court



25



---

##### Table of Contents

dismissed without prejudice only our former officers, Dale R. Pfost and Donald R. Marvin, from the litigation in exchange
for us entering into a tolling agreement with plaintiffs executive committee. On February 19, 2003, we received notice of the courts decision to dismiss the Section 10(b) claims against us. Plaintiffs and the defendant issuers
involved in this IPO securities litigation, including us, have agreed in principal on a settlement that, upon a one-time surety payment by the defendant issuers insurers, would release the defendant issuers and the individual officers and
directors from claims and any future payments or out-of-pocket costs. On March 10, 2005, the court issued a memorandum and order (i) preliminarily approving the settlement, contingent on the parties agreement on modifications of the
proposed bar order in the settlement documents, (ii) certifying the parties proposed settlement classes, (iii) certifying the proposed class representatives for the purposes of the settlement only and (iv) setting a further
hearing for the purposes of (a) making a final determination as to the form, substance and program of notice of proposed settlement and (b) scheduling a public fairness hearing in order to determine whether the settlement can be finally
approved by the court. On April 24, 2006, the court held a fairness hearing but did not rule on the motion for final approval of the settlement.

We are a defendant in litigation pending in the Southern District of New York entitled Enzo Biochem, Inc. et al. v. Amersham PLC, et al, filed in October 2002. By their complaint, plaintiffs allege that certain
defendants (i) breached their distributorship agreements by selling certain products for commercial development (which they allege was not authorized), (ii) infringed plaintiffs patents through the sale and use of certain products,
and (iii) are liable for fraud, unfair competition and tortious interference with contractual relations. We did not have a contractual relationship with plaintiffs, but we are alleged to have purchased the product at issue from one of the other
defendants. We have sold the business unit that was allegedly engaged in the unlawful conduct. As a result, there is no relevant injunctive relief to be sought from us. The complaint seeks damages in an undisclosed amount. Most of the fact discovery
in the case has been taken, and a Markman hearing to construe the patent claims was conducted in early July 2005. On July 17, 2006, the Court ruled in our favor on its construction of the patents asserted against us, and the co-defendants,
including us, plan to move for summary judgment in the fall of 2006.

Additionally, we have certain other claims against us arising
from the normal course of our business. The ultimate resolution of such matters, including those cases disclosed above, in the opinion of management, will not have a material effect on our financial position, but could have a material impact on our
results of operations for any reporting period.

Item 1A. RISK FACTORS

Except for the addition of the following risk factors, there have not been
any material changes from the risk factors as disclosed under the heading Risk Factors appearing in Item 1A of our Annual Report on Form 10-K for the year ended December 31, 2005.

We currently receive a significant percentage of our annual gross revenue through our relationship with FAL and our agreement with FAL has been terminated.

We perform forensic testing services for several police forces throughout the UK through our agreement with FAL. Revenues derived
through the FAL agreement accounted for approximately 23% and 31% of our total revenues for the three months ended June 30, 2006 and 2005, respectively, and approximately 25% and 30% of our total revenues for the six months ended June 30,
2006 and 2005, respectively. Revenues derived through the FAL agreement accounted for approximately 51% and 65% of our UK revenues for the three months ended June 30, 2006 and 2005, respectively, and approximately 56% and 66% of our UK
revenues for the six months ended June 30, 2006 and 2005, respectively. In 2005, FAL was acquired by LGC, a provider of analytical and diagnostic services, including DNA testing services, and to that extent is in a position to compete for the
business we currently conduct for FAL. On July 7, 2006, we received from FAL notice of termination of this agreement, effective July 15, 2007. We have been and are implementing plans to enable us to directly provide our services to UK
police forces and extend our offerings of forensic services. As a result of our receipt of the notice of termination, we are in discussions with LGC regarding the transitioning of services we provide to UK police forces, including addressing the
provision of services to police forces whose contract with FAL extends beyond the termination of our contract with FAL. We continue to expect our UK operations to be a significant part of our business. If our discussions with LGC do not
result in an acceptable transition of the services we perform on behalf of FAL or if we are unable to successfully implement plans to enable us to directly provide our services to UK police forces, including having in place in a timely manner the
necessary personnel and infrastructure, or are unsuccessful in securing a sufficient number of agreements directly with UK police forces, our business would be materially adversely affected.



26



---

##### Table of Contents

We expect to need additional cash to sustain our operations and there can be no assurance of our ability to obtain
sufficient cash for this purpose.

We believe our existing cash balances will be sufficient to sustain our operations for at least
the next twelve months, however, we do expect to need additional cash as our turnaround continues and we seek to grow the company. We may not be able to raise additional funds or raise funds on terms that are acceptable to us, if at all. In
addition, as a result of our failure to file our Annual Report on Form 10-K for the year ended December 31, 2005 and our Quarterly Report on Form 10-Q for the quarter ended March 31, 2006 by their filing deadlines, our securities cannot be
registered on or traded under a registration statement on Form S-3 until we regain compliance with the requirements for the use of that form which may limit our ability to successfully raise additional funds or raise funds on terms that are
acceptable to us. If future financing is not available to us, or is not available on terms acceptable to us, we may not be able to fund our future needs. If we raise funds through equity or convertible securities, our stockholders may experience
dilution and our stock price may decline. We cannot assure you that our business or operations will not consume available resources more rapidly than anticipated. We also cannot assure you that we will not require additional funding beyond amounts
currently anticipated before we can achieve profitable operations. We also may need additional capital if we seek to acquire other businesses or technologies.

Item 2. UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS

Not applicable.

Item 3. DEFAULTS UPON SENIOR SECURITIES

Not applicable.

Item 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

Not applicable.

Item 5. OTHER INFORMATION

As previously disclosed, Dr. George Poste, Chairman of our Board of
Directors, was to serve as our principal executive officer until we filed with the SEC our Quarterly Report on Form 10-Q for the first quarter of 2006 and amended Quarterly Reports on Form 10-Q for the second and third quarters of 2005. We have
already filed our Quarterly Report on Form 10-Q for the first quarter of 2006. However, we have since elected not to file amended Quarterly Reports on Form 10-Q for the second and third quarters of 2005, and as a result, Mr. Thomas A.
Bologna, our President and Chief Executive Officer, is now serving as our principal executive officer.

Item 6. EXHIBITS



|              |  |                                                                                                                                                                                                                                                                                                          
|------------- |  | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|ExhibitNumber |  | Description                                                                                                                                                                                                                                                                                              
|10.1          |  | Separation Agreement and Release by and between the Registrant and Paul J. Kelly dated as of April 24, 2006. Previously filed with the Commission as Exhibit 99.1 to, and incorporated herein
by reference from, the Registrants Current Report on Form 8-K filed with the Commission on April 27, 2006.
|              | 
|31.1          |  | Certification of Principal Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002                                                                                                                                                                                                   
|              | 
|31.2          |  | Certification of Principal Financial and Accounting Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002                                                                                                                                                                                    
|              | 
|32            |  | Certifications of Principal Executive Officer and Principal Financial and Accounting Officer pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.                                                                                                                                                  



27



---

##### Table of Contents

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly
caused this report to be signed on its behalf by the undersigned thereunto duly authorized.



|                     |  |                      |  |                                                                                  
|-------------------- |  | -------------------- |  | ---------------------------------------------------------------------------------
|                     |  | ORCHID CELLMARK INC.
|                     |  |                     
|Date: August 9, 2006 |  | By:                  |  | /s/ John C. Deighan                                                              
|                     |  |                      |  | John C. Deighan Corporate
Controller (Principal Financial and Accounting Officer)



28



---

##### Table of Contents

Exhibits

The
following is a list of exhibits filed as part of this Quarterly Report on Form 10-Q.



|              |  |                                                                                                                                                                                                                                                                                                          
|------------- |  | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|ExhibitNumber |  | Description                                                                                                                                                                                                                                                                                              
|10.1          |  | Separation Agreement and Release by and between the Registrant and Paul J. Kelly dated as of April 24, 2006. Previously filed with the Commission as Exhibit 99.1 to, and incorporated herein
by reference from, the Registrants Current Report on Form 8-K filed with the Commission on April 27, 2006.
|              | 
|31.1          |  | Certification of Principal Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002                                                                                                                                                                                                   
|              | 
|31.2          |  | Certification of Principal Financial and Accounting Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002                                                                                                                                                                                    
|              | 
|32            |  | Certifications of Principal Executive Officer and Principal Financial and Accounting Officer pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.                                                                                                                                                  



29