I U C L I D

 D a t a s e t

Existing Chemical Substance ID: 68140–01–2

CAS No. 68140–01–2

EINECS Name Amides, coco, N–[3–(dimethylamino)propyl]

EINECS No. 268–771–8

Molecular Formula <no data>

Dataset created by: EUROPEAN COMMISSION – European Chemicals Bureau

This dossier is a compilation based on data reported by the European

Chemicals Industry following ’Council Regulation (EEC) No. 793/93

on the Evaluation and Control of the Risks of Existing Substances’.

All (non–confidential) information from the single datasets, submitted

in the IUCLID/HEDSET format by individual companies, was integrated

to create this document.

The data have not undergone any evaluation by the European Commission.

Creation date: 19–FEB–2000

Number of Pages: 17

Chapters: all

Edition: Year 2000 CD–ROM edition

Flags: non–confidential

 (C) 2000 EUROPEAN COMMISSION

 European Chemicals Bureau
 date: 19–FEB–2000

1. General Information Substance ID: 68140–01–2

______________________________________________________________________________

1.0.1 OECD and Company Information

Name: Albright & Wilson UK Limited

Street: 210–222 Hagley Road West

Town: B68 0NN Oldbury

Country: United Kingdom

Phone: +44 121 429 4942

Telefax: +44 121 420 5151

Telex: 336291

Name: Clariant GmbH

Town: 65926 Frankfurt am Main

Country: Germany

Name: Clariant UK Ltd.

Street: Calverley lane

Town: 25184RP Horsforth, Leeds

Country: United Kingdom

Name: Croda Universal Ltd

Street: Cowick Hall, Snaith

Town: DN14 9AA Goole, North Humberside

Country: United Kingdom

Phone: 0405 860551

Telefax: 0405 860205

Telex: 57601

Cedex: DN14 9AA

Name: F.LLI RICCI S.R.L.

Street: A. COLOMBO 128

Town: 20055 GORLA MINORE (VA)

Country: Italy

Phone: 0331–365385

Telefax: 0331–365759

Name: Goldschmidt Italia S.r.l.

Street: Falconera, 7

Town: 26025 Pandino

Country: Italy

Phone: 0373–9751

Telefax: 0373–975260

Name: Henkel KGaA

Street: Henkelstr. 67

Town: 40589 Duesseldorf

Country: Germany

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 date: 19–FEB–2000

1. General Information Substance ID: 68140–01–2

______________________________________________________________________________

Name: Huels AG

Street: Postfach

Town: D–45764 Marl

Country: Germany

Name: KAO Corporation S.A.

Street: Puig dels Tudons 10

Town: 08210 Barbera del Valles

Country: Spain

Name: STEPAN EUROPE

Street: Chemin Jongkind / BP127

Town: 38340 Voreppe

Country: France

1.0.2 Location of Production Site

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1.0.3 Identity of Recipients

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1.1 General Substance Information

Substance type: organic

Physical status: liquid

Substance type: organic

Physical status: solid

Substance type: organic

Physical status:

1.1.1 Spectra

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1.2 Synonyms

Alkamide CAP

Source: Henkel KGaA Duesseldorf

Amida CHF (KAO)

Source: KAO Corporation S.A. Barbera del Valles

Amides, coco, N–[3–(dimethylamino)propyl]

Source: Henkel KGaA Duesseldorf

Amindes, coco, N–[3–(dimethylamino)propyl]

Source: Hoechst AG Frankfurt/Main

 Clariant GmbH Frankfurt am Main

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 date: 19–FEB–2000

1. General Information Substance ID: 68140–01–2

______________________________________________________________________________

Aminoamid

Source: Henkel KGaA Duesseldorf

Cocamidopropyl dimethylamine

Source: KAO Corporation S.A. Barbera del Valles

 Goldschmidt Italia S.r.l. Pandino

Cocamidopropyl Dimethylamine

Source: Croda Universal Ltd Goole, North Humberside

COCAMIDOPROPYL DIMETHYLAMINE

Source: Henkel KGaA Duesseldorf

COCAMIDOPROPYL DIMETHYLAMINE (INCI)

Source: Henkel KGaA Duesseldorf

Cocamidopropyldimethylamine

Source: Henkel KGaA Duesseldorf

Coco amides, N–[3–(dimethylamino)propyl]

Source: Henkel KGaA Duesseldorf

Coco amides, N–[‘3–(dimethylamino)propyl]

Source: KAO Corporation S.A. Barbera del Valles

Coconut fatty acid, dimethylaminopropylamid

Source: Henkel KGaA Duesseldorf

Coconut fatty acid, dimethylaminopropylamide

Source: Henkel KGaA Duesseldorf

Coconut fatty acid, dimethylaminopropylamide (ALTSTOFF)

Source: Henkel KGaA Duesseldorf

Dimethylaminopropylkokosfettsäureamid

Source: Henkel KGaA Duesseldorf

MARLAMID JB

Source: Huels AG Marl

Mazeen CA

Source: Henkel KGaA Duesseldorf

N,N–Dimethyl–N(C8–18–kokosacylamidopropyl)amin

Source: Henkel KGaA Duesseldorf

N–[3–(Dimethylamino)propyl] coco amides

Source: Henkel KGaA Duesseldorf

N–[‘3–(Dimethylamino)propyl] coco amides

Source: KAO Corporation S.A. Barbera del Valles

1.3 Impurities

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 date: 19–FEB–2000

1. General Information Substance ID: 68140–01–2

______________________________________________________________________________

1.4 Additives

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1.5 Quantity

Quantity 10 000 – 50 000 tonnes

1.6.1 Labelling

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1.6.2 Classification

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1.7 Use Pattern

Type: type

Category: Non dispersive use

Type: type

Category: Use in closed system

Type: type

Category: Wide dispersive use

Type: type

Category:

Type: industrial

Category: Chemical industry: used in synthesis

Type: industrial

Category: Paints, lacquers and varnishes industry

Type: industrial

Category: Personal and domestic use

Type: industrial

Category: Textile processing industry

Type: use

Category: Cosmetics

Type: use

Category: Intermediates

Type: use

Category: Surface–active agents

Type: use

Category: other: Pigmentpräparation

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 date: 19–FEB–2000

1. General Information Substance ID: 68140–01–2

______________________________________________________________________________

1.7.1 Technology Production/Use

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1.8 Occupational Exposure Limit Values

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1.9 Source of Exposure

Remark: Manufactured at one site only

Source: Croda Universal Ltd Goole, North Humberside

1.10.1 Recommendations/Precautionary Measures

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1.10.2 Emergency Measures

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1.11 Packaging

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1.12 Possib. of Rendering Subst. Harmless

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1.13 Statements Concerning Waste

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1.14.1 Water Pollution

Classified by: other: Henkel

Labelled by:

Class of danger: 2 (water polluting)

Remark: Self classification by Henkel KGaA

Source: Transfer program

 Henkel KGaA Duesseldorf

Classified by: other: Hoechst AG

Labelled by: other: Selbsteinstufung

Class of danger: 2 (water polluting)

Source: Hoechst AG Frankfurt/Main

 Clariant GmbH Frankfurt am Main

 (1)

1.14.2 Major Accident Hazards

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1.14.3 Air Pollution

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 – 5/17 –
 date: 19–FEB–2000

1. General Information Substance ID: 68140–01–2

______________________________________________________________________________

1.15 Additional Remarks

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1.16 Last Literature Search

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1.17 Reviews

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1.18 Listings e.g. Chemical Inventories

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 – 6/17 –
 date: 19–FEB–2000

2. Physico–chemical Data Substance ID: 68140–01–2

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2.1 Melting Point

Value:

Source: F.LLI RICCI S.R.L. GORLA MINORE (VA)

2.2 Boiling Point

Value: > 200 degree C

Source: F.LLI RICCI S.R.L. GORLA MINORE (VA)

2.3 Density

Type: density

Value: 1.06 g/cm3 at 20 degree C

Source: Henkel KGaA Duesseldorf

 (2)

2.3.1 Granulometry

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2.4 Vapour Pressure

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2.5 Partition Coefficient

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2.6.1 Water Solubility

Value: < 10 g/l at 20 degree C

pH: ca. 9 at 5 g/l and 20 degree C

Source: F.LLI RICCI S.R.L. GORLA MINORE (VA)

Value: at 20 degree C

Qualitative: of high solubility

Source: Henkel KGaA Duesseldorf

 (2)

2.6.2 Surface Tension

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2.7 Flash Point

Value: > 100 degree C

Type:

Method:

 Year:

Source: Henkel KGaA Duesseldorf

 (2)

 – 7/17 –
 date: 19–FEB–2000

2. Physico–chemical Data Substance ID: 68140–01–2

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2.8 Auto Flammability

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2.9 Flammability

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2.10 Explosive Properties

Result: not explosive

Source: F.LLI RICCI S.R.L. GORLA MINORE (VA)

2.11 Oxidizing Properties

Result: no oxidizing properties

Source: F.LLI RICCI S.R.L. GORLA MINORE (VA)

2.12 Additional Remarks

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 – 8/17 –
 date: 19–FEB–2000

3. Environmental Fate and Pathways Substance ID: 68140–01–2

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3.1.1 Photodegradation

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3.1.2 Stability in Water

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3.1.3 Stability in Soil

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3.2 Monitoring Data (Environment)

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3.3.1 Transport between Environmental Compartments

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3.3.2 Distribution

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3.4 Mode of Degradation in Actual Use

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3.5 Biodegradation

Type: aerobic

Inoculum: other: sewage treatment plant effluent/biological stage

Concentration: 5 mg/l related to DOC (Dissolved Organic Carbon)

Degradation: 26 – 37 % after 28 day

Method: Directive 84/449/EEC, C.3 "Biotic degradation – modified OECD

 screening test"

 Year: GLP:

Test substance: as prescribed by 1.1 – 1.4

Method: EG–RiLi 84/449 Anh.V C4–B

Remark: stark schwankende, z.T. negative Zwischenwerte

Source: Henkel KGaA Duesseldorf

Test condition: #1: 5 mg/l referring to DOC: 26% with parameter %

 DOC–Abnahme

 #2: 10 mg/l referring to DOC: 37% with parameter %

 DOC–Abnahme

 (3) (4)

 – 9/17 –
 date: 19–FEB–2000

3. Environmental Fate and Pathways Substance ID: 68140–01–2

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Type: aerobic

Inoculum: other: sewage treatment plant effluent/biological stage

Concentration: 2 mg/l

Degradation: 86 – 81 % after 30 day

Result: readily biodegradable

Method: Directive 84/449/EEC, C.6 "Biotic degradation – closed bottle

 test"

 Year: GLP:

Test substance: as prescribed by 1.1 – 1.4

Method: EG–RiLi 84/449 Anh.V C4–E

Remark: erhebliche Trübung der Prüfmusterstammlösung.

Source: Henkel KGaA Duesseldorf

Test condition: #1: 2 mg/l referring to Active Substance: 86% with parameter

 % BSB/CSB

 #2: 5 mg/l referring to Active Substance: 81% with parameter

 % BSB/CSB

 (5) (6)

Type: aerobic

Inoculum: other: sewage treatment plant effluent/biological stage

Degradation: 65 % after 28 day

Result: other: biodegradable

Method: OECD Guide–line 301 D "Ready Biodegradability: Closed Bottle

 Test"

 Year: 1991 GLP:

Test substance: as prescribed by 1.1 – 1.4

Source: Henkel KGaA Duesseldorf

 (7)

3.6 BOD5, COD or BOD5/COD Ratio

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3.7 Bioaccumulation

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3.8 Additional Remarks

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 – 10/17 –
 date: 19–FEB–2000

4. Ecotoxicity Substance ID: 68140–01–2

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AQUATIC ORGANISMS

4.1 Acute/Prolonged Toxicity to Fish

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4.2 Acute Toxicity to Aquatic Invertebrates

Species: Daphnia magna (Crustacea)

Exposure period: 24 hour(s)

Unit: mg/l Analytical monitoring:

EC0: = .4

EC50: = .63

EC100: = 1

Method: OECD Guide–line 202, part 1 "Daphnia sp., Acute

 Immobilisation Test"

 Year: 1991 GLP:

Test substance: as prescribed by 1.1 – 1.4

Result: related to test substance

Source: Henkel KGaA Duesseldorf

Test substance: Active Matter = 100%

 (7)

Species: Daphnia magna (Crustacea)

Exposure period: 48 hour(s)

Unit: mg/l Analytical monitoring:

EC0: = .2

EC50: = .4

EC100: = .8

Method: OECD Guide–line 202, part 1 "Daphnia sp., Acute

 Immobilisation Test"

 Year: 1991 GLP:

Test substance: as prescribed by 1.1 – 1.4

Result: related to test substance

Source: Henkel KGaA Duesseldorf

Test substance: Active Matter = 100%

 (7)

4.3 Toxicity to Aquatic Plants e.g. Algae

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 – 11/17 –
 date: 19–FEB–2000

4. Ecotoxicity Substance ID: 68140–01–2

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4.4 Toxicity to Microorganisms e.g. Bacteria

Type:

Species: Pseudomonas putida (Bacteria)

Exposure period: 16 hour(s)

Unit: mg/l Analytical monitoring:

EC10: = 280

EC50: = 570

Method: other: DIN 38 412/8, Zellvermehrungshemmtest

 Year: 1991 GLP:

Test substance: as prescribed by 1.1 – 1.4

Result: related to test substance

Source: Henkel KGaA Duesseldorf

Test substance: Active Matter = 100%

 (7)

4.5 Chronic Toxicity to Aquatic Organisms

4.5.1 Chronic Toxicity to Fish

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4.5.2 Chronic Toxicity to Aquatic Invertebrates

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TERRESTRIAL ORGANISMS

4.6.1 Toxicity to Soil Dwelling Organisms

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4.6.2 Toxicity to Terrestrial Plants

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4.6.3 Toxicity to other Non–Mamm. Terrestrial Species

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4.7 Biological Effects Monitoring

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4.8 Biotransformation and Kinetics

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4.9 Additional Remarks

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 – 12/17 –
 date: 19–FEB–2000

5. Toxicity Substance ID: 68140–01–2

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5.1 Acute Toxicity

5.1.1 Acute Oral Toxicity

Type: LD50

Species: rat

Sex:

Number of

 Animals:

Vehicle:

Value: > 2000 mg/kg bw

Method: Directive 84/449/EEC, B.1 "Acute toxicity (oral)"

 Year: GLP: no data

Test substance: as prescribed by 1.1 – 1.4

Source: Henkel KGaA Duesseldorf

 (8)

Type: LD50

Species: rat

Sex:

Number of

 Animals:

Vehicle:

Value: = 200 – 2000 mg/kg bw

Method: Directive 84/449/EEC, B.1 "Acute toxicity (oral)"

 Year: GLP: no data

Test substance: as prescribed by 1.1 – 1.4

Source: Henkel KGaA Duesseldorf

 (8)

5.1.2 Acute Inhalation Toxicity

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5.1.3 Acute Dermal Toxicity

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5.1.4 Acute Toxicity, other Routes

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5.2 Corrosiveness and Irritation

 – 13/17 –
 date: 19–FEB–2000

5. Toxicity Substance ID: 68140–01–2

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5.2.1 Skin Irritation

Species: rabbit

Concentration:

Exposure:

Exposure Time:

Number of

 Animals:

PDII:

Result: corrosive

EC classificat.:

Method: OECD Guide–line 404 "Acute Dermal Irritation/Corrosion"

 Year: GLP: no data

Test substance: as prescribed by 1.1 – 1.4

Source: Henkel KGaA Duesseldorf

 (9)

Species: other: hairless mouse

Concentration:

Exposure:

Exposure Time:

Number of

 Animals:

PDII:

Result: irritating

EC classificat.:

Method:

 Year: GLP: no data

Test substance: as prescribed by 1.1 – 1.4

Remark: The substance was applied once.

Source: Henkel KGaA Duesseldorf

 (9)

Species: other: hairless mouse

Concentration:

Exposure:

Exposure Time:

Number of

 Animals:

PDII:

Result: moderately irritating

EC classificat.:

Method:

 Year: GLP: no data

Test substance: as prescribed by 1.1 – 1.4

Remark: The substance was applied once daily to the same area of

 skin and gently massaged into it.

Source: Henkel KGaA Duesseldorf

 (9)

 – 14/17 –
 date: 19–FEB–2000

5. Toxicity Substance ID: 68140–01–2

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5.2.2 Eye Irritation

Species: rabbit

Concentration:

Dose:

Exposure Time:

Comment:

Number of

 Animals:

Result: irritating

EC classificat.:

Method: OECD Guide–line 405 "Acute Eye Irritation/Corrosion"

 Year: GLP: no data

Test substance: as prescribed by 1.1 – 1.4

Source: Henkel KGaA Duesseldorf

 (9)

5.3 Sensitization

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5.4 Repeated Dose Toxicity

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5.5 Genetic Toxicity ’in Vitro’

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5.6 Genetic Toxicity ’in Vivo’

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5.7 Carcinogenicity

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5.8 Toxicity to Reproduction

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5.9 Developmental Toxicity/Teratogenicity

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5.10 Other Relevant Information

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5.11 Experience with Human Exposure

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 – 15/17 –
 date: 19–FEB–2000

6. References Substance ID: 68140–01–2

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 (1) Hoechst AG (1995): EG–Sicherheitsdatenblatt Hoe S 3267–3

 (19.12.95)

 (2) HENKEL KGaA, SDS, 4/1998, ’Dehyton K Vorstufe’, DED 00085570

 (3) Henkel KGaA, unpublished data, File 13, Page/Assay 449

 (4) Henkel KGaA, unpublished data, Protocol 21, Page/Assay 449

 (5) Henkel KGaA, unpublished data, File 61, Page/Assay 744

 (6) Henkel KGaA, unpublished data, Protocol 32, Page/Assay 744

 (7) Henkel KGaA, unpublished data, Archive–No. R 9601945

 (External Report, Inst. Fresenius, 09/1991)

 (8) Henkel KGaA, unpublished data, Archive–No. TBD 850340

 (9) Henkel KGaA, unpublished data, Archive–No. TBD 850317

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 date: 19–FEB–2000

7. Risk Assessment Substance ID: 68140–01–2

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7.1 Risk Assessment

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 – 17/17 –