Exhibit
10.9


 


FIRST AMENDMENT
TO LEASE


 


This First Amendment
to Lease (“Amendment”) is made effective as of May 22, 2014, by and between PLAZA DEL ORO GREEN, L.P., a Delaware
limited liability company (‘‘Landlord”) and PLx PHARMA INC. a Texas corporation (“Tenant’’)
with reference to the following facts and circumstances.


 


		A.	Landlord is the owner of that certain building located
at 8285 El Rio. Houston, Texas 77054 (the ‘‘Building”).



 


		B.	Teachers Insurance and Annuity Association of America,
predecessor in interest to Landlord, and Tenant entered into that certain Industrial Multi-Tenant Lease dated June 4,2009, (the
‘‘Lease’’) for certain premises containing approximately 3,905 rentable square feet (the ··Premises”)
located in the Building.



 


		C.	Landlord and Tenant desire to amend the Lease upon terms
and conditions hereinafter set forth .



 


NOW, THEREFORE, in
consideration of the foregoing facts and circumstances, the mutual covenants and promises contained herein and after good and valuable
consideration, the receipt and sufficiency of which is acknowledged by each of the parties, the parties do hereby agree to the
following:


 


1.           Definitions.
Each capitalized term used in this Amendment shall have the same meaning as is ascribed to such capitalized term in the Lease,
unless otherwise provided for herein.


 


2.           Term.
The term of the Lease is
hereby extended for a term commencing on July I,
2014 and ending on June 30,
2015 (the “Extended Term’’). Tenant
shall have no option to
renew the Lease following the Extended Term
and as of the full execution of this Amendment the renewal option set forth in Exhibit C
of the Lease is hereby deleted and of no further force
and effect.


 


3.           Base
Rent. Base Rent for the Extended Term shall
be as follows:


 


	Months	 	Monthly Installment	 	 	Annual	 
	July l, 2014 - June 30, 2015	 	$	3,202.10	 	 	$	38,425.20	 



 


4.           No
Defenses. Tenant affirms that, as of the date or execution or this Amendment: (a) no default or breach by Landlord exists under
the Lease; (b) all tenant improvements to be constructed by Landlord prior to the date of this Amendment, if” any, are complete
and Tenant has accepted the Premises in “as is. where is” condition as of the date of this Amendment; (c) Landlord
has fully funded or Tenant has waived any unfunded tenant improvement allowances payable under the Lease: and (d) Tenant has no
defenses. offsets or counterclaims that could be asserted in an action by Landlord to enforce Landlord’s remedies under the
Lease.


 




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5.           Broker.
Tenant represents to Landlord that except for Holt Lunsford Commercial (the “Broker’’), Tenant has not dealt
with any real estate broker, salesperson or finder in connection with this Amendment, and no other such person initiated or participated
in the negotiation of this Amendment or is entitled to any commission in connection herewith. Tenant hereby agrees to indemnify,
defend and hold Landlord, its property manager and their respective employees harmless from and against any and all liabilities,
claims, demands, actions. damages, costs and expenses (including attorneys’ fees) arising from either
(a) a claim for a fee or commission made by
any broker, other than
the Broker, claiming to have acted by
or on behalf of Tenant in
connection with this Amendment, or (b) a
claim of, or right to lien under the
statutes of the state in which the Premises
are located relating
to real estate broker liens
with respect to any such broker
retained by Tenant.


 


6.           Submission.
Submission of this Amendment by Landlord to Tenant for examination and/or execution shall not in any manner bind Landlord and no
obligations on Landlord shall arise under this Amendment unless and until this Amendment is fully signed and delivered by Landlord
and Tenant; provided, however, the execution and delivery by Tenant of this Amendment to Landlord shall constitute an irrevocable
offer by Tenant of the terms and conditions herein contained, which offer may not be revoked for thirty (30) days after such delivery.


 


7.           Notice.


 


(a)          Landlord’s
Address for both Notice and Rent Payments for set forth in the Lease shall be deleted and replaced with the following:


 


PLAZA DEL ORO GREEN , L.P.

c/o Greenfield Partners, LLC

2 Post Road West

Westport, CT 06880


Attn: Barry P. Marcus


  


With Copy To:


 


Stream Realty Partners

515 Post Oak Blvd., Suite 100

Houston, Texas 77027


Attn: Chris Bosler


 


8.           Miscellaneous.


 


(a)          Time
of Essence. Time is of the essence of this Amendment and each and every term and provision hereof.


 


(b)          Modification.
A modification of any provision herein contained, or any other amendment to this Amendment. shall be effective only if the modification
or amendment is in writing and signed by both Landlord and Tenant.


 


(c)          Successors
and Assigns. This Amendment shall be binding upon and inure to the benefit of the parties hereto and their respective successors
and permitted assigns.


 


(d)          Number
and Gender. As used in this Amendment, the neuter includes masculine and feminine, and the singular includes the plural.


 




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(e)         Construction.
Headings at the beginning or each S .:ction and subsection are solely for the convenience or the parties and are not a part of
this Amendment. Except as otherwise provided in this Amendment, all exhibits referred to herein are attached hereto and are incorporated
herein by this reference. Unless otherwise indicated, all references herein to Articles, Section, subsections. paragraphs. subparagraphs
or provisions are to those in this Amendment. Any reference to a paragraph or Section herein includes all subparagraphs or subsections
thereof. This Amendment shall not be construed as if it had been prepared by only Landlord or Tenant, but rather as if both Landlord
and Tenant had prepared the same. In the event any portion of this Amendment shall be declared by any court of competent jurisdiction
to be invalid, illegal or unenforceable, such portion shall be deemed severed from this Amendment, and the remaining parts hereof
shall remain in full force and effect, as fully as though such invalid, illegal or unenforceable portion had never been part of
this Amendment.


 


(f)           Integration
of Other Agreements. This Amendment, the Lease and prior amendments set forth the entire agreement and understanding of the
parties with respect to the matters set forth herein and supersedes all previous written or oral understandings, agreements, contracts,
correspondence and documentation with respect thereto. Any oral representation or modifications concerning this Amendment shall
be of no force or effect.


 


(g)          Duplicate
Originals: Counterparts. This Amendment may be executed in any number of duplicate originals, all of which shall be of equal
legal force and effect. Additionally, this Amendment may be executed in counterparts, but shall become effective only after a counterpart
hereof has been executed by each party; all said counterparts shall, when taken together, constitute the entire single agreement
between parties.


 


(h)          No
Waiver. No failure or delay of either party in the exercise of any right given to such party hereunder shall constitute a waiver
thereof unless the time specified herein for exercise of such right has expired. nor shall any single or partial exercise of any
right preclude other or further exercise thereof or of any other right. No waiver by any party hereto of any breach or default
shall be considered to be a waiver of any other breach or default. The waiver of any condition shall not constitute a waiver of
any breach or default \>Vith respect to any covenant, representation or warranty.


 


(i)           Further
Assurances. Landlord and Tenant each agree to execute any and all other documents and to take any further actions reasonably
necessary to consummate the transactions contemplated hereby.


 


(j)           No
Third Party Beneficiaries. Except as otherwise provided herein, no person or entity shall be deemed to be a third party beneficiary
hereof, and nothing in this Amendment, (either expressed or implied) is intended to confer upon any person or entity, other than
Landlord and/or Tenant (and their respective nominees, successors and assigns), any rights, remedies. obligations or liabilities
under or by reason of this Amendment.


 


(k)          Full
Force and Effect. The Lease, as amended hereby , shall continue in full force and effect, subject to the terms and provisions
thereof and hereof. In the event or any conflict between the terms of the Lease and the terms of this Amendment, the terms of this
Amendment shall control.


 




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IN WITNESS WHEREOF,
this Amendment is executed as of the day and year aforesaid.


 


	 	LANDLORD:
	 	 
	 	PLAZA Del ORO GREEN, L.P.
	 	 
	 	By:	/s/ Barry P. Marcus
	 	Barry P. Marcus, Senior Vice President
	 	 
	 	Date: 5/29/2014


 


	 	TENANT:
	 	 
	 	PLx PHARMA INC.
	 	 
	 	By:	/s/ Ronald R. Zimmerman
	 	Ronald R. Zimmerman
	 	President
	 	 
	 	Date: 5/22/2014


 




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