Form of Consulting Agreement



  Exhibit 10.22 

CONSULTING AGREEMENT 

This CONSULTING AGREEMENT (the “Agreement”) is made and entered into this
             day of             , 2010, by and between Furiex Pharmaceuticals, Inc., a Delaware corporation (the
“Company”), and Fredric N. Eshelman (“Consultant”). 
 1. Services. Consultant will provide senior
strategic oversight services, assist the President and Chief Medical Officer of the Company with executive functions, executive decision-making and senior management integration, assist the Company with investor relations matters and provide other
services as needed or requested by the Company (collectively, the “Services”). Consultant agrees to perform the Services in a diligent, timely and professional manner, with a high level of care and skill, and as directed by the Company.

 2. Compensation and Expenses. 

(a) Option Grant. To compensate Consultant for providing the Services, the Company will grant to Employee (i) on or before the
expiration of the 60-day period following the completion of the Company’s spin-off from Pharmaceutical Product Development, Inc. (“PPDI”) as an independent public company (the “Spin-Off”) options to purchase shares equal to
two percent (2.0%) of the Company’s common stock outstanding immediately after the completion of the Spin-Off (the “Initial Option Grant”) and (ii) on or about the second anniversary of the Spin-Off options to purchase shares equal to
one percent (1.0%) of the Company’s common stock outstanding the date of such grant (the “Subsequent Option Grant”). The Initial Option Grant and the Subsequent Option Grant will be subject to the terms and conditions of the
Company’s 2010 Stock Plan (the “Stock Plan”) and such other stock option award agreements and/or terms and conditions as the Company’s Board of Directors (the “Board”) may require. In addition, the Initial Option Grant
and the Subsequent Option Grant will be subject to a three-year linear vesting schedule under which one-third of the total number of options granted under the Initial Option Grant and the Subsequent Option Grant will vest on each of the first,
second and third anniversaries of the respective grant date. The Initial Option Grant and the Subsequent Option Grant will have an exercise price based on the fair market value of the Company’s common stock on the respective date of grant as
provided in the Stock Plan. 
  (b) Business Expenses. While Consultant is engaged by the Company, the Company will
reimburse Consultant for Consultant’s reasonable and necessary business expenses incurred in connection with providing the Services, provided that Consultant timely submits any request for reimbursement and provided further that Consultant
provides required documentation and otherwise complies with the Company’s expense reimbursement policies. 
 3.
Independent Contractor Status. This Agreement does not create an employer-employee relationship between the Company and Consultant. It is the parties’ intention that Consultant will be an independent contractor and not the Company’s
employee for any purposes, including, but not limited to, the application of the Fair Labor Standards Act minimum wage and overtime provisions, the Federal Insurance Contribution Act, the Social Security Act, the Federal Unemployment Tax Act, the
provisions of the Internal Revenue Code and all state and local laws and regulations. Consultant will retain sole and absolute discretion and judgment in the manner and means of carrying out Consultant’s activities and responsibilities
hereunder. While engaged as a consultant to the Company, Consultant does not have the authority to enter into any contract on behalf of the Company or otherwise to bind the Company to any agreement unless expressly authorized in writing to do so,
and the Company will not be liable for any obligation incurred by Consultant, including, but not limited to, unpaid minimum wages and/or overtime premiums. 

While Consultant is engaged by the Company, the parties agree and acknowledge that Consultant will remain employed as the Executive
Chairman of PPDI. As provided on Exhibit A hereto, PPDI consents to Consultant’s engagement with the Company as set out herein. The parties further agree and acknowledge that Consultant’s duties hereunder may not interfere with or
adversely affect Consultant’s duties and obligations to PPDI. 







  4. Termination. Either party may terminate this Agreement and Consultant’s
consulting engagement hereunder at any time, for any reason, upon thirty (30) days’ prior written notice to the other party. In no event will Consultant be entitled to compensation for any services provided or business expenses incurred
after the parties’ consulting relationship or this Agreement terminates. If Consultant terminates his engagement hereunder at any time, for any reason or if Consultant’s engagement hereunder terminates due to Consultant’s death or
disability (as “disability” is defined in Section 11 of the Stock Plan), then unless the Board approves otherwise, any unvested options granted under the Initial Option Grant and the Subsequent Option Grant will terminate and no
longer be exercisable as of the date Consultant’s engagement with the Company terminates (“Termination Date”). If the Company terminates Consultant’s engagement hereunder at any time without Cause (as “Cause” is defined
in Section 10 of the Stock Plan), then all unvested options granted under the Initial Option Grant and the Subsequent Option Grant will immediately vest and be exercisable as of the Termination Date. If the Company terminates Consultant’s
engagement hereunder for Cause (as defined in Section 10 of the Stock Plan), then all of Consultant’s then unexercised options (whether vested or not) granted under the Initial Option Grant and the Subsequent Option Grant will terminate as
of the Termination Date. 
  5. Confidentiality and Nondisclosure. Consultant hereby acknowledges that during the
course of this engagement, Consultant will be exposed to and work with clients and others providing services to or employed with the Company sharing data, trade secrets, non-public financial information, non-public personnel information, product
plans, customer lists, marketing plans and strategies, systems, manuals, forecasts and other business information, improvements, inventions, business strategies, business methods and practices, formulas, product ideas, biological material and
techniques, chemical and/or information analysis and related products and data, computer programs and software, software designs and documentation, source codes, algorithms, techniques, schematics, know-how and data, and any other material which is
related to the Company’s business, proprietary in nature, confidential to the Company and not generally available to the public or its competitors and which, if divulged, would be potentially damaging to the Company’s ability to compete in
the marketplace (hereinafter referred to as the “Proprietary Information”). Consultant agrees not to use or disclose any Proprietary Information belonging to the Company for or to any person or entity, except if necessary to perform the
Services, as authorized in writing by the Company, or as may be required by court order, statute, law or regulation. If Consultant is required by applicable law, court order or regulation to disclose any Proprietary Information, Consultant will
provide the Company with at least five business days’ prior written notice of such anticipated disclosure and will cooperate with the Company to minimize the extent of any such compelled disclosure. For purposes of this Agreement, Proprietary
Information does not include: (a) information unrelated to the Company’s business; (b) information that is generally known to the public or is publicly available (through no breach of this Agreement by Consultant); or
(c) information made known to Consultant by a third party under no obligation of confidentiality to the Company. 
 6.
Assignment of Rights in Proprietary Information and Inventions. 
 (a) Assignment of Rights in Proprietary
Information. All Proprietary Information and all patents, copyrights, trade secret rights and other rights (including throughout, without limitation, any extensions, renewals, continuations or divisions of any of the foregoing) in connection
therewith shall be the sole property of the Company. Consultant hereby assigns to the Company any rights Consultant may have or acquire in such Proprietary Information. 
  


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 (b) Works for Hire; Assignment of Inventions. Consultant will promptly disclose to
the Company, or any persons designated by it, all “Inventions,” which includes all improvements, inventions, formulas, ideas, works of authorship, processes, computer programs and software, software designs and documentation, algorithms,
techniques, schematics, know-how data, whether or not patentable, made or conceived or reduced to practice or developed by Consultant, either alone or jointly with others, while engaged by the Company and for six (6) months thereafter.
Consultant agrees that all Inventions that Consultant makes, conceives, reduces to practice or develops (in whole or in part, either alone or jointly with others) during his consultancy with the Company shall be the sole property of the Company to
the maximum extent permitted by law, and, to the extent permitted by law, shall be “works made for hire.” The Company shall be the sole owner of all patents, copyrights, trade secret rights, and other intellectual property or other rights
in connection therewith. Consultant hereby assigns to the Company any rights he may have or acquire in such Inventions. Consultant agree to perform, during and after his engagement with the Company, all acts deemed necessary or desirable by the
Company to permit and assist it, at the Company’s expense, in obtaining and enforcing patents, copyrights, trade secret rights or other rights on such Inventions and/or any other Inventions Consultant has or may at any time assign to the
Company in any and all countries. Such acts may include, but are not limited to, execution of documents and assistance or cooperation in legal proceedings. With respect to any and all matters arising out of or relating to Consultant’s
consulting engagement with the Company, Consultant hereby irrevocably designates and appoints the Company and its duly authorized officers and agents, as his agents and attorneys-in-fact to act for and on Consultant’s behalf and instead of
Consultant, to execute and file any applications or related filings and do all other lawfully permitted acts to further the prosecution and issuance of patents, copyrights, trade secret rights or other rights thereon with the same legal force and
effect as if executed by Consultant. 
 (c) Excluded Inventions. Consultant agrees to attach a complete list of all
Inventions or improvements to which he claims ownership and/or that he desires to remove from the operation of this Agreement, and he covenants that such list is complete. If no such list is attached to this Agreement, Consultant represents that he
has no such Inventions and improvements at the time of signing this Agreement. Consultant understands that any such list shall not contain information that breaches an obligation of confidentiality with any third party. 

7. Return of Company Property. Upon request of the Company or no later than termination of the consulting relationship described
in this Agreement by either party for any reason, Consultant agrees to return all materials belonging to the Company, including, without limitation, any Company credit cards, Company-owned equipment, and all originals and any copies of all disks,
tapes, files, correspondence, notes and other documents pertaining to the Company’s proprietary products, customers, business, Proprietary Information as defined in Section 5 of this Agreement and/or Inventions as defined in Section 6
of this Agreement. 
 8. Injunctive Relief. In the event of a breach or threatened breach of Sections 5 or 6 of this
Agreement by Consultant, the Company will be entitled, in addition to any other relief provided at law or equity, to equitable relief in the form of a temporary, preliminary or permanent injunction restraining Consultant from violating any provision
included in Sections 5 or 6 of this Agreement. 
 9. Consultant Warranties. Consultant represents and warrants that his
performance of all terms under this Agreement does not and will not breach any duty owed by him to PPDI or any other third party, under contract or otherwise, or violate any confidence of PPDI or any other third party. Consultant agrees not to
disclose to the Company or induce the Company to use any confidential or proprietary information belonging to any third party. Consultant warrants that Consultant has not and will not execute any noncompetition, nondisclosure or confidentiality
agreements that would in any way interfere with Consultant providing the Services to the Company. 
  

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 10. Limited Liability. EXCEPT WITH RESPECT TO ANY CLAIMS ARISING UNDER SECTIONS 5 OR
6 OF THIS AGREEMENT, OR ANY CLAIMS RELATED TO EITHER PARTY’S INTENTIONAL MISCONDUCT OR GROSS NEGLIGENCE, NEITHER PARTY WILL BE LIABLE TO THE OTHER PARTY FOR ANY LOST PROFITS, CONSEQUENTIAL, INCIDENTAL, INDIRECT, EXEMPLARY, SPECIAL OR PUNITIVE
DAMAGES, REGARDLESS OF WHETHER THE CLAIM GIVING RISE TO SUCH DAMAGES IS BASED UPON BREACH OF WARRANTY, BREACH OF CONTRACT OR NEGLIGENCE, EVEN IF A PARTY HAS BEEN ADVISED OF THE POSSIBILITY THEREOF. EXCEPT WITH RESPECT TO ANY CLAIMS ARISING UNDER
SECTION 5 OR 6 OF THIS AGREEMENT, OR ANY CLAIMS RELATED TO EITHER PARTY’S INTENTIONAL MISCONDUCT OR GROSS NEGLIGENCE, EACH PARTY’S LIABILITY TO THE OTHER FOR ANY CAUSE OF ACTION ARISING OUT OF OR RELATING TO THIS AGREEMENT WILL NOT EXCEED
THE AGGREGATE VALUE OF ANY COMPENSATION PROVIDED TO CONSULTANT UNDER THIS AGREEMENT. 
 11. Entire Agreement. This
Agreement represents the entire agreement between the parties regarding the subject matter hereof. It replaces and supersedes any and all prior oral or written agreements or understandings between the parties regarding the subject matter hereof.

 12. Successors and Assigns. This Agreement is binding upon and inures to the benefit of any heirs, successors and
permitted assigns of the parties. Consultant may not assign any rights and obligations hereunder without the prior written consent of the Company. The Company may assign its rights and obligations to any successor in interest. 

13. Notices. All notices required by this Agreement must be in writing. A notice may be delivered to a party at the address that
follows a party’s signature on the parties’ signature page below, or to a new address that a party designates in writing. A notice may be delivered: 
  

	 	•	 	 in person 


  

	 	•	 	 by certified mail, or 


  

	 	•	 	 by overnight courier. 



14. Governing Law; Venue. This Agreement will be governed by and construed in accordance with the laws of the state of North
Carolina, without regard to its conflict of laws principles. In the event of any dispute between the parties arising out of or related to this Agreement, the state or federal courts sitting in Wake County, North Carolina will have the sole and
exclusive power to adjudicate such disputes. The Company and Consultant also hereby irrevocably consent to the personal jurisdiction of the state or federal courts sitting in Wake County, North Carolina. 

15. Counterparts. This Agreement may be signed by the parties in different counterparts and the signature pages combined will
create a document binding on all parties. 
 16. Modification. This Agreement may be modified only in a writing signed by
both the parties. 
 17. Waiver. If one party waives any term or provision of this Agreement at any time, that waiver
will be effective only for the specific instance and specific purpose for which the waiver was given. If either party fails to exercise or delays exercising any of its rights or remedies under this Agreement, that party retains the right to enforce
that term or provision at a later time. 
  

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 18. Severability. If any court determines that any provision of this Agreement is
invalid or unenforceable, any invalidity or unenforceability will affect only that provision and will not make any other provision of this Agreement invalid or unenforceable and such provision will be modified, amended or limited only to the extent
necessary to render it valid and enforceable. 
 19. Survival. Sections 5 through 18 of this Agreement will survive the
termination of Consultant’s engagement hereunder, regardless of the party terminating the engagement and regardless of the manner or cause of such termination. 

[Signature page follows.] 
  

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 IN WITNESS WHEREOF, Company and Consultant have executed this Consulting Agreement as of the
last date set forth below. 
  

			
	 COMPANY:

	
	 Furiex Pharmaceuticals, Inc.

		
	 By:
	 	  

	 Name:
	 	  

	 Title:
	 	  




 

			
	 Address:
	 	3900 Paramount Parkway, Suite 150 Morrisville, North Carolina 27560
	
	 CONSULTANT:

	
	  

	 Fredric N. Eshelman

		
	 Address:
	 	  

		 	  




 

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 EXHIBIT A 

Pharmaceutical Product Development, Inc. (“PPDI”) hereby consents to the engagement of its Executive Chairman, Fredric N.
Eshelman, to serve as a consultant to Furiex Pharmaceuticals, Inc. (“Furiex”) on the terms and conditions described in the attached Consulting Agreement between Dr. Eshelman and Furiex (the “Consulting Agreement”). In
addition, PPDI further waives any rights it may have to terminate the employment of Dr. Eshelman under the May 19, 2009 Amended and Restated Employment Agreement between Dr. Eshelman and PPDI (the “Employment Agreement”)
because of the consulting relationship between Dr. Eshelman and Furiex and/or the Consulting Agreement, provided that Dr. Eshelman’s duties for Furiex do not interfere with his obligations to PPDI and provided further that
Dr. Eshelman is otherwise in compliance with all other material terms of the Employment Agreement. 
  

			
	 PHARMACEUTICAL PRODUCT

DEVELOPMENT, INC.

		
	 By:
	 	  

	 Name:
	 	  

	 Title:
	 	  

	 Date:
	 	  




 

			
	 Address:
	 	 929 North Front Street

Wilmington, North Carolina 28401-3331



  

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