Exhibit 10.58

Millennium Pharmaceuticals, Inc. has entered into an indemnification agreement on the terms set forth on the attached indemnification agreement with each
of the below-named executive officers and directors of Millennium, on the dates indicated:

Name of executive officer or director

Date of ExecutionDeborah Dunsire

February 28, 2008Marsha H. Fanucci

February 28, 2008Christophe Bianchi

February 28, 2008Joseph B. Bolen

February 28, 2008Stephen M. Gansler

February 28, 2008Laurie B. Keating

February 28, 2008Anna Protopapas

February 28, 2008Nancy Simonian

February 28, 2008Peter F. Smith

February 28, 2008Robert F. Friel

February 28, 2008A. Grant Heidrich, III

February 28, 2008Charles J. Homcy

February 28, 2008Raju S. Kucherlapati

February 28, 2008Jeffrey M. Leiden

February 28, 2008Mark J. Levin

February 28, 2008Norman C. Selby

February 28, 2008Kenneth E. Weg

February 28, 2008Anthony H. Wild

February 28, 2008


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INDEMNIFICATION AGREEMENT

This Agreement is made as of the                        day of
February 2008, by and between Millennium Pharmaceuticals, Inc., a Delaware corporation (the
"Corporation), and                                    (the
"Indemnitee"), a director or officer of the Corporation.

WHEREAS,
it is essential to the Corporation to retain and attract as directors and officers the most capable persons available, and

WHEREAS,
the substantial increase in corporate litigation subjects directors and officers to expensive litigation risks at the same time that the availability of directors' and officers'
liability insurance has been severely limited, and

WHEREAS,
it is now and has always been the express policy of the Corporation to indemnify its directors and officers, and

WHEREAS,
the Indemnitee does not regard the protection available under the Corporation's Certificate of Incorporation and insurance as adequate in the present circumstances, and may not
be willing to serve or continue to serve as a director or officer without adequate protection, and

WHEREAS,
the Corporation desires the Indemnitee to serve, or continue to serve, as a director or officer of the Corporation.

NOW
THEREFORE, the Corporation and the Indemnitee do hereby agree as follows:

1.Agreement to Serve.The Indemnitee agrees to serve or continue to serve as a director or officer of the
Corporation for so long as the Indemnitee is duly elected or appointed or until such time as the Indemnitee tenders a resignation in writing.

2.Definitions.As used in this Agreement:



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3.Indemnity of Indemnitee.Subject to Sections 6, 7 and 9, the Corporation shall indemnify the
Indemnitee in connection with any Proceeding as to which the Indemnitee is, was or is threatened to be made a party (or is otherwise involved) by reason of the Indemnitee's Corporate Status, to the
fullest extent permitted by law (as such may be amended from time to time). In furtherance of the foregoing and without limiting the generality thereof:



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4.Indemnification of Expenses of Successful Party.Notwithstanding any other provision of this Agreement, to
the extent that the Indemnitee has been successful, on the merits or otherwise, in defense of any Proceeding or in defense of any claim, issue or matter therein (other than a Proceeding referred to in
Section 6), the Indemnitee shall be indemnified against all Expenses actually and reasonably incurred by or on behalf of the Indemnitee in connection therewith. Without limiting the foregoing,
if any Proceeding or any claim, issue or matter therein is disposed of, on the merits or otherwise (including a disposition without prejudice), without (i) the disposition being adverse to the
Indemnitee, (ii) an adjudication that the Indemnitee was liable to the Corporation, (iii) a plea of guilty ornolo contendereby the
Indemnitee, (iv) an adjudication that the Indemnitee did not act in good faith and in a manner the Indemnitee reasonably believed to be in or not opposed to the best interests of the
Corporation, and (v) with respect to any criminal proceeding, an adjudication that the Indemnitee had reasonable cause to believe his or her conduct was unlawful, the Indemnitee shall be
considered for the purposes hereof to have been wholly successful with respect thereto.

5.Indemnification for Expenses of a Witness.To the extent that the Indemnitee is, by reason of the
Indemnitee's Corporate Status, a witness in any Proceeding to which the Indemnitee is not a party, the Indemnitee shall be indemnified against all Expenses actually and reasonably incurred by or on
behalf of the Indemnitee in connection therewith.

6.Exceptions to Right of Indemnification.Notwithstanding anything to the contrary in this Agreement, except as
set forth in Section 10, the Corporation shall not indemnify the Indemnitee in connection with a Proceeding (or part thereof) initiated by the Indemnitee unless (a) the initiation
thereof was approved by the Board or (b) the Proceeding was commenced following a Change in Control. Notwithstanding anything to the contrary in this Agreement, the Corporation shall not
indemnify the Indemnitee to the extent the Indemnitee is reimbursed from the proceeds of insurance, and in the event the Corporation makes any indemnification payments to the Indemnitee and the

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Indemnitee
is subsequently reimbursed from the proceeds of insurance, the Indemnitee shall promptly refund such indemnification payments to the Corporation to the extent of such insurance
reimbursement.

7.Notification and Defense of Claim.As a condition precedent to the Indemnitee's right to be indemnified, the
Indemnitee must notify the Corporation in writing as soon as practicable of any Proceeding for which indemnity will or could be sought. With respect to any Proceeding of which the Corporation is so
notified, the Corporation will be entitled to participate therein at its own expense and/or to assume the defense thereof at its own expense, with legal counsel reasonably acceptable to the
Indemnitee. After notice from the Corporation to the Indemnitee of its election so to assume such defense, the Corporation shall not be liable to the Indemnitee for any legal or other expenses
subsequently incurred by the Indemnitee in connection with such Proceeding, other than as provided below in this Section 7. The Indemnitee shall have the right to employ his or her own counsel
in connection with such Proceeding, but the fees and expenses of such counsel incurred after notice from the Corporation of its assumption of the defense thereof shall be at the expense of the
Indemnitee unless (i) the employment of counsel by the Indemnitee has been authorized by the Corporation, (ii) counsel to the Indemnitee shall have reasonably concluded that there may be
a conflict of interest or position on any significant issue between the Corporation and the Indemnitee in the conduct of the defense of such Proceeding or (iii) the Corporation shall not in
fact have employed counsel to assume the defense of such Proceeding, in each of which cases the fees and expenses of counsel for the Indemnitee shall be at the expense of the Corporation, except as
otherwise expressly provided by this Agreement, and provided that Indemnitee's counsel shall cooperate reasonably with the Corporation's counsel to minimize the cost of defending claims against the
Corporation and the Indemnitee. The Corporation shall not be entitled, without the consent of the Indemnitee, to assume the defense of any claim brought by or in the right of the Corporation or as to
which counsel for the Indemnitee shall have reasonably made the conclusion provided for in clause (ii) above. The Corporation shall not be required to indemnify the Indemnitee under this
Agreement for any amounts paid in settlement of any Proceeding effected without its written consent. The Corporation shall not settle any Proceeding in any manner that would impose any penalty or
limitation on the Indemnitee without the Indemnitee's written consent. Neither the Corporation nor the Indemnitee will unreasonably withhold or delay their consent to any proposed settlement.

8.Advancement of Expenses.In the event that the Corporation does not assume the defense pursuant to
Section 7 of any Proceeding of which the Corporation receives notice under this Agreement, any Expenses incurred by or on behalf of the Indemnitee in defending such Proceeding shall be paid by
the Corporation in advance of the final disposition of such Proceeding;provided, however, that the payment of such Expenses incurred by or on behalf of
the Indemnitee in advance of the final disposition of such Proceeding shall be made only upon receipt of an undertaking by or on behalf of the Indemnitee to repay all amounts so advanced in the event
that it shall ultimately be determined that the Indemnitee is not entitled to be indemnified by the Corporation as authorized in this Agreement. Such undertaking shall be accepted without reference to
the financial ability of the Indemnitee to make repayment. Any advances and undertakings to repay pursuant to this Section 8 shall be unsecured and interest free.

9.Procedures.



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10.Remedies.The right to indemnification or advancement of Expenses as provided by this Agreement shall be
enforceable by the Indemnitee in any court of competent jurisdiction if the Corporation denies such request, in whole or in part, or if no disposition thereof is made within the applicable period
referred to in Section 9. Unless otherwise required by law, the burden of proving that indemnification or advancement of Expenses is not appropriate shall be on the Corporation. Neither the
failure of the Corporation to have made a determination prior to the commencement of such action that indemnification is proper in the circumstances because the Indemnitee has met the applicable
standard of conduct, nor an actual determination by the Corporation that the Indemnitee has not met such applicable standard of conduct, shall be a defense to the action or create a presumption that
the Indemnitee has not met the applicable standard of conduct. The Indemnitee's Expenses actually and reasonably incurred in connection with successfully establishing the Indemnitee's right to
indemnification, in whole or in part, in any such Proceeding shall also be indemnified by the Corporation.

11.Partial Indemnification.If the Indemnitee is entitled under any provision of this Agreement to
indemnification by the Corporation for some or a portion of the Expenses, judgments, fines, penalties or amounts paid in settlement actually and reasonably incurred by or on behalf of the Indemnitee
in connection with any Proceeding but not, however, for the total amount thereof, the Corporation shall nevertheless indemnify the Indemnitee for the portion of such Expenses, judgments, fines,
penalties or amounts paid in settlement to which the Indemnitee is entitled.

12.Subrogation.In the event of any payment under this Agreement, the Corporation shall be subrogated to the
extent of such payment to all of the rights of recovery of the Indemnitee, who shall execute all papers required and take all action necessary to secure such rights, including execution of such
documents as are necessary to enable the Corporation to bring suit to enforce such rights.

13.Term of Agreement.This Agreement shall continue until and terminate upon the later of (a) six years
after the date that the Indemnitee shall have ceased to serve as a director or officer of the Corporation or, at the request of the Corporation, as a director, officer, partner, trustee, member,
employee or agent of another corporation, partnership, joint venture, trust, limited liability company or other enterprise or (b) the final termination of all Proceedings pending on the date
set forth in clause (a) in respect of which the Indemnitee is granted rights of indemnification or advancement of Expenses hereunder and of any proceeding commenced by the Indemnitee pursuant
to Section 10 of this Agreement relating thereto.

14.Indemnification Hereunder Not Exclusive.The indemnification and advancement of Expenses provided by this
Agreement shall not be deemed exclusive of any other rights to which the Indemnitee may be entitled under the Certification of Incorporation, the By-Laws, any other agreement, any vote of
stockholders or disinterested directors, the General Corporation Law of Delaware, any other law

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(common
or statutory), or otherwise, both as to action in the Indemnitee's official capacity and as to action in another capacity while holding office for the Corporation. Nothing contained in this
Agreement shall be deemed to prohibit the Corporation from purchasing and maintaining insurance, at its expense, to protect itself or the Indemnitee against any expense, liability or loss incurred by
it or the Indemnitee in any such capacity, or arising out of the Indemnitee's status as such, whether or not the Indemnitee would be indemnified against such expense, liability or loss under this
Agreement; provided that the Corporation shall not be liable under this Agreement to make any payment of amounts otherwise indemnifiable hereunder if and to the extent that the Indemnitee has
otherwise actually received such payment under any insurance policy, contract, agreement or otherwise.

15.No Special Rights.Nothing herein shall confer upon the Indemnitee any right to continue to serve as an
officer or director of the Corporation for any period of time or at any particular rate of compensation.

16.Savings Clause.If this Agreement or any portion thereof shall be invalidated on any ground by any court of
competent jurisdiction, then the Corporation shall nevertheless indemnify the Indemnitee as to Expenses, judgments, fines, penalties and amounts paid in settlement with respect to any Proceeding to
the full extent permitted by any applicable portion of this Agreement that shall not have been invalidated and to the fullest extent permitted by applicable law.

17.Counterparts.This Agreement may be executed in any number of counterparts, each of which shall constitute
the original.

18.Successors and Assigns.This Agreement shall be binding upon the Corporation and its successors and assigns
and shall inure to the benefit of the estate, heirs, executors, administrators and personal representatives of the Indemnitee.

19.Headings.The headings of the paragraphs of this Agreement are inserted for convenience only and shall not
be deemed to constitute part of this Agreement or to affect the construction thereof.

20.Modification and Waiver.This Agreement may be amended from time to time to reflect changes in Delaware law
or for other reasons. No supplement, modification or amendment of this Agreement shall be binding unless executed in writing by both of the parties hereto. No waiver of any of the provisions
of this Agreement shall be deemed or shall constitute a waiver of any other provision hereof nor shall any such waiver constitute a continuing waiver.

21.Notices.All notices, requests, demands and other communications hereunder shall be in writing and shall be
deemed to have been given (i) when delivered by hand or (ii) if mailed by certified or registered mail with postage prepaid, on the third day after the date on which it is so mailed:



or
to such other address as may have been furnished to the Indemnitee by the Corporation or to the Corporation by the Indemnitee, as the case may be.

22.Applicable Law.This Agreement shall be governed by, and construed and enforced in accordance with, the laws
of the State of Delaware. The Indemnitee may elect to have the right to indemnification or reimbursement or advancement of Expenses interpreted on the basis of the

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applicable
law in effect at the time of the occurrence of the event or events giving rise to the applicable Proceeding, to the extent permitted by law, or on the basis of the applicable law in effect
at the time such indemnification or reimbursement or advancement of Expenses is sought. Such election shall be made, by a notice in writing to the Corporation, at the time indemnification or
reimbursement or advancement of Expenses is sought; provided, however, that if no such notice is given, and if the General Corporation Law of Delaware is amended, or other Delaware law is enacted, to
permit further indemnification of the directors and officers, then the Indemnitee shall be indemnified to the fullest extent permitted under the General Corporation Law, as so amended, or by such
other Delaware law, as so enacted.

23.Enforcement.The Corporation expressly confirms and agrees that it has entered into this Agreement in order
to induce the Indemnitee to continue to serve as an officer or director of the Corporation, and acknowledges that the Indemnitee is relying upon this Agreement in continuing in such capacity.

24.Entire Agreement.This Agreement sets forth the entire agreement of the parties hereto in respect of the
subject matter contained herein and supercedes all prior agreements, whether oral or written, by any officer, employee or representative of any party hereto in respect of the subject matter contained
herein; and any prior agreement of the parties hereto in respect of the subject matter contained herein is hereby terminated and cancelled. For avoidance of doubt, the parties confirm that the
foregoing does not apply to or limit the Indemnitee's rights under Delaware law or the Corporation's Certificate of Incorporation or By-Laws.

25.Consent to Suit.In the case of any dispute under or in connection with this Agreement, the Indemnitee may
only bring suit against the Corporation in the Court of Chancery of the State of Delaware. The Indemnitee hereby consents to the exclusive jurisdiction and venue of the courts of the State of
Delaware, and the Indemnitee hereby waives any claim the Indemnitee may have at any time as to forum non conveniens with respect to such venue. The Corporation shall have the right to institute any
legal action arising out of or relating to this Agreement in any court of competent jurisdiction. Any judgment entered against either of the parties in any proceeding hereunder may be entered and
enforced by any court of competent jurisdiction.

IN
WITNESS WHEREOF, the parties hereto have caused this Agreement to be duly executed as of the day and year first above written.

|        |  |  | MILLENNIUM PHARMACEUTICALS, INC.
|------- |  |  | --------------------------------
|Attest: |  |  | By:                             
|        |  |  |                                 
|By:     |  |  | Name:                           
|        |  |  |                                 
|Name:   |  |  | Title:                          
|        |  |  |                                 
|Title:  |  |  |                                 
|        |  |  |                                 

|
|

| |  |  | INDEMNITEE: | 
| |  |  | ----------- | 
| |  |  |            

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