UNITED STATES
SECURITIES AND EXCHANGE COMMISSIONWashington, D.C. 20549

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FORM 10-K

ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d)
OF THE SECURITIES EXCHANGE ACT OF 1934
For the fiscal year ended December 31, 2003
Commission File Number: 1-12213

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COVANCE INC.(Exact name of Registrant as specified in its Charter)

Delaware(State of Incorporation)

22-3265977(I.R.S. Employer Identification No.)210 Carnegie Center, Princeton, New Jersey(Address of Principal Executive Offices)

08540(Zip Code)


Registrant's
telephone number, including area code: (609) 452-4440

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Securities
registered pursuant to Section 12(b) of the Act:

Title of Each ClassCommon Stock, $.01 Par Value

Name of Each Exchangeon Which RegisteredNew York Stock Exchange


Securities
registered pursuant to Section 12(g) of the Act: None

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Indicate by check mark whether the Registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the
Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the Registrant was required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days. Yes X No

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of
Regulation S-K is not contained herein, and will not be contained, to the best of the Registrant's knowledge, in definitive proxy or information statements incorporated by reference
in Part III of this Form 10-K or any amendment to this Form 10-K. X

Indicate by checkmark whether the registrant is an accelerated filer (as defined in
Rule 12b-2 of the Act). Yes X No

The aggregate market value of the shares of common stock held by non-affiliates of the
Registrant was $1,102,975,700 on June 30, 2003, the last business day of Registrant's most recently completed second fiscal quarter.

As of February 11, 2004, the Registrant had 62,726,655 shares of Common Stock outstanding.

DOCUMENTS INCORPORATED BY REFERENCE

The Company's definitive Proxy Statement is incorporated by reference into Items 10, 11, 12, 13, and 14 of Part III
of this Form 10-K.



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PART I

Item 1.    Business

General

Covance Inc. is a leading drug development services company providing a wide range of early stage and late stage product development
services on a
worldwide basis primarily to the pharmaceutical, biotechnology and medical device industries. We also provide laboratory testing services to the chemical, agrochemical and food industries. We believe
Covance is one of the largest drug development services companies, based on annual net revenues, and one of a few that are capable of providing comprehensive global product development services.
Covance, a Delaware corporation, was incorporated in 1994. Covance maintains offices in 18 countries.

Business Strategy

Drug development services companies like Covance typically derive substantially all of their revenue from the research, development and
marketing expenditures of
the pharmaceutical, biotechnology and medical
device industries. We believe outsourcing of these services has increased in the past and may increase in the future because of several factors, including: pressures to contain costs, limitations on
internal capacity, the need for faster development time for new drugs, research in multiple countries simultaneously, stringent government regulation, and expertise that customers lack internally. We
believe the investment and amount of time required to develop new drugs has been increasing, and that these trends create opportunities for companies that can help make the process of drug development
more efficient.

Our
strategy is to provide services that will generate high quality and timely data in support of new drug approval or use expansion. We do this by developing and delivering innovative
high quality services that apply science and technology and global reach to capture, manage and integrate a vast array of drug development data.

Innovative Technology.We intend to capitalize on our investments in carefully selected
hardware and software products,
systems and networks and our information systems professionals to provide processes and solutions for both employees and clients to meet the changing demands of drug development. In
December 2003, we entered into an agreement with IBM to manage our information technology infrastructure including our computer and telephone network, e-mail system, help desks,
computer support and data centers worldwide. The arrangement is intended to allow us to focus our global IT resources on applications that will help deliver our services to customers faster and more
efficiently. In the past several years, we introduced new internet-based products.



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We
continue to pursue new innovative systems and use those systems to improve the provision of drug development data to our customers.

Global Reach.We believe that it is important to provide a broad range of drug research
and development services on a global
basis. We have offices, regional monitoring sites, and laboratories in over 30 locations in 18 different countries and conduct field work in many other countries. We believe we are a leader among drug
development services companies in our ability to deliver services globally.

Acquisitions.In addition to internal development of services, we consider strategic
acquisitions that are complementary to
our existing services and that expand our ability to serve our clients. While we cannot exclude the possibility that we may opportunistically seek to take advantage of other situations, we generally
expect acquisitions to enhance our existing services either qualitatively or geographically or to add new services that can be integrated with our existing services.

Services

The services we provide constitute two segments for financial reporting purposes: (1) early development services, which includes
preclinical services and
Phase I clinical services, and (2) late-stage development services, which includes central laboratory, clinical development, periapproval, central ECG diagnostic services, and
healthcare economic and reimbursement services. Although each segment has separate services within it, they can be combined in joint service offerings and we believe clients increasingly are
interested in the opportunities for such combined services.

Early Development

Preclinical Services

Our preclinical services include toxicology services and pharmaceutical chemistry and related services. Our preclinical area has been a
source of innovation by
introducing new technologies for client access to data such as Study Tracker, electronic animal identification, multimedia study reports, and animal and test tube measures of induced cell
proliferation or reproduction. We have laboratories in locations which include Madison, Wisconsin and Vienna, Virginia in the United States and Harrogate, United Kingdom and Muenster, Germany in
Europe. We also have bioanalytical laboratories in the United States in Indianapolis, Indiana and Chantilly, Virginia, and an administrative and sales office in Tokyo, Japan. In 2002, we
completed a significant expansion of our Madison, Wisconsin facility and in 2003 we expanded our Harrogate, United Kingdom facility.

Toxicology.Our preclinical toxicology services includein
vivotoxicology
studies, which are studies of the effects of drugs in animals, and genetic toxicology studies, which include studies of the effects of drugs on chromosomes, as well as on genetically modified mice. We
offer immunotoxicology services in which we assess the impact of drugs or chemicals on the structure and function of the immune system. Our immunotoxicology and cell culture laboratory features online
data capture capabilities and instrumentation monitoring systems that are designed to be compliant with Good Laboratory Practices.

Pharmaceutical Chemistry.In our pharmaceutical chemistry services, we determine the
metabolic profile and bioavailability
of drug candidates. We also provide laboratory testing services to the chemical, agricultural chemical and food industries. We offer a complete range of services to agricultural chemical manufacturers
to determine the potential risk to humans, animals and the environment from plant protection products such as pesticides. We also offer a broad range of services to the food and nutriceutical
industries, including nutritional analysis and nutritional content fact labels.

Research Products.We provide custom polyclonal and monoclonal antibody services for
research purposes and
purpose-bred animals for biomedical research. These research animals are required by pharmaceutical and biotechnology companies, university research centers and contract research
organizations as part of their required preclinical animal safety and efficacy testing. Through a variety of processes,

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technology
and specifically constructed facilities, we provide purpose-bred, pre-acclimated and specific pathogen free animals that meet our clients' rigorous quality control
requirements.

BioLink®.In 2000, we introduced our BioLink service offering. This bioanalytical
testing service, which is
conducted in our bioanalytical laboratory in Indianapolis, Indiana and in our immunoanalytical facility in Chantilly, Virginia, helps determine the appropriate dose and frequency of drug application
from late discovery evaluation through Phase III clinical testing on a full-scale, globally integrated basis.

Phase I Clinical Services

We provide Phase I clinical services, primarily first-in-human trials of new pharmaceuticals, at our clinics in Madison, Wisconsin, and
Leeds, United Kingdom. In December 2003, we opened a new state-of-the-art clinic in Madison, Wisconsin.

Late-Stage Development

Central Laboratory Services

We provide central laboratory services on a global basis. We have three central laboratories, one in each of the United States,
Switzerland and Singapore that
provide central laboratory services to biotechnology and pharmaceutical customers. We also have contractual arrangements with a leading South African laboratory and a leading Australian laboratory.

Our
capabilities provide clients the flexibility to conduct studies on a multinational and simultaneous basis. The data we provide is combinable because we use consistent laboratory
methods, the same reagent manufacturers and identical equipment calibration and clinical trial reference ranges. Combinable data eliminates the cumbersome process of statistically correlating results
generated using different methods and different laboratories on different equipment. In 2002, in order to enhance data combinability, we acquired Virtual Central Laboratory b.v., a Netherlands-based
company which uses a proprietary system to harmonize laboratory results from local and regional laboratories to help expand the reach of traditional central laboratory services.

We
also employ a proprietary clinical trials management system that enables us to enter a sponsor's protocol requirements directly into our database. The laboratory data can be audited
because all laboratory data can be traced to source documents. In addition, the laboratories are capable of delivering customized data electronically within 24 hours of test completion. Covance
also offers pharmacogenomic testing and sample storage technologies in conjunction with our central laboratory services.

Clinical Development Services

We offer a comprehensive range of clinical trial services, including Phase II and III clinical studies. We have extensive experience in a
number of therapeutic
areas, and we provide the following core services either on an individual or aggregated basis to meet clients' needs:



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We
have extensive experience in managing small, medium and large trials in the United States, Europe and in many other parts of the world. These trials may be conducted separately or
simultaneously as part of a multinational development plan. We can manage every aspect of clinical trials from clinical development plans and protocol design to New Drug Applications, among other
supporting services.

Clinical Trial Support Services

Central Diagnostics.Our ability to collect and centralize clinical trial data is
enhanced by our central diagnostics
service offerings which include the capture and interpretation of electrocardiograms. Electrocardiogram analysis, one of the most frequently used tools in clinical trials, is included in more than
one-half of clinical trials as part of the study protocol. We distribute a proprietary hand-held electrocardiogram device to clinical trial sites. The device, which can be used
anywhere in the world, collects the data, performs a real-time quality check, and transmits the information by telephone to a full-time central operations center where
cardiologists read the results. In 1999, Covance introduced ambulatory cardiac monitoring capabilities, often referred to as Holter monitoring. Holter monitoring involves the ambulatory monitoring of
cardiac activity and permits long-term monitoringoften 24 to 48 hours as opposed to the ten seconds of data typically provided by stationary ECGs, and therefore may
reveal certain conditions which may not be discovered by a stationary ECG.

In
2000, we opened a centralized imaging center to meet a growing pharmaceutical industry need for imaging to document clinical efficacy and safety. In 2002, we introduced
Digitography, a proprietary system for use in clinical trials which allows on screen digital ECG waveform measurement with resolution unmatched in the industry. In 2003, Central
Diagnostics was relocated to a new and larger facility in Reno, Nevada.

Interactive Voice Response Services.To expedite the drug development process and to
help reduce costs, we created a
proprietary interactive trial management system. This system uses touch-tone telephone technology for data entry purposes and assists our clients in managing clinical trials on a
real-time basis and in reducing product waste with just-in-time inventory processing. This system, which is multi-lingual, is available world-wide
through toll-free numbers 24 hours per day, seven days per week. The most frequently used functions include patient screening, patient enrollment, patient randomization, drug
assignments, drug inventory management, unblinding, discontinuations and patient diaries. We offer this system both in conjunction with clinical trials we conduct and as a stand-alone service.

Commercialization Services

Periapproval Services.Periapproval trials are studies conducted "around the time of NDA
approval", generally after a drug
has successfully undergone clinical efficacy and safety testing and the New Drug Application has been submitted to the Food and Drug Administration ("FDA"). We offer a range of periapproval services,
including:



We
also field and process telephone calls and inquiries relating to adverse experiences with a drug while we perform the safety services in the context of periapproval studies.

Health Economics and Outcomes Services.We offer a wide range of health economics
services, including outcomes and
pharmacoeconomic studies, reimbursement planning and reimbursement advocacy

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programs.
Pharmaceutical, biotechnology and medical device manufacturers purchase these services from us to help optimize their return on research and development investments.

Divested Businesses

In February 2001, Covance sold its pharmaceutical packaging business, which offered full-service contract drug packaging services for
clinical
trials, for the aggregate amount of $137.5 million. In June 2001, Covance sold its biomanufacturing unit, Covance Biotechnology Services Inc., which manufactured recombinant
proteins for biotechnology and pharmaceutical clients, for the aggregate amount of approximately $190 million, including the assumption of debt and other liabilities. Primarily as a result of
these divestitures, Covance substantially eliminated debt, improved its cash flow and focused on its core services.

Customers and Marketing

We provide product development services on a global basis to, among others, the pharmaceutical and biotechnology industries. In 2003, we
served in excess of 300
biopharmaceutical companies, ranging from the world's largest pharmaceutical companies and biotechnology companies to small and start-up organizations.

While
no single customer accounted for more than five percent of our aggregate net revenue in 2003, we had three customers accounting for more than five but less than ten percent of our
revenues, and our top five customers accounted for approximately 25 percent of our net revenues. In each of our early development and late-stage development segments individually, no single
customer accounted for more than 10 percent of revenue. Our late-stage development segment had five customers which each accounted for more than five but less than ten percent of
its aggregate net revenues. Our early development segment had one customer accounting for more than five but less than ten percent of its aggregate net revenues.

For
net revenues from external customers, assets attributable to each of our business segments and other segment information for each of the last three fiscal years, please review
Note 12 to the audited consolidated financial statements included elsewhere in this Annual Report.

For
net revenues from external customers and long-lived assets attributable to operations in the United States, United Kingdom, Switzerland and other countries for each of
the last three fiscal years, please review Note 13 to the audited consolidated financial statements included elsewhere in this Annual Report.

Our
global sales activities are conducted by sales personnel based in our operations in the United States, Canada, Europe, Australia, Japan and Singapore.

Contractual Arrangements

Many of our contracts with our clients are either fixed price or fee-for-service with a cap. To a lesser extent, some of our contracts
are fee-for-service without a cap. In cases where the contracts are fixed price, we generally bear the cost of overruns, but we benefit if the costs are lower than we
anticipated. In cases where our contracts are fee-for-service with a cap, the contracts contain an overall budget for the trial based on time and cost estimates. If our costs
are lower than anticipated, the customer generally keeps the savings, but if our costs are higher than estimated, we are responsible for the overrun unless the increased cost is a result of a change
requested by the customer, such as an increase in the number of patients to be enrolled or the type or amount of data to be collected. Contracts may range from a few months to several years or longer
depending on the nature of the work performed. In some cases for multi-year contracts, a portion of the contract fee is paid at the time the study or trial is started with the balance of
the contract fee payable in installments upon the achievement of milestones over the study or trial duration.

Most
of our contracts may be terminated by the customer either immediately or upon notice. These contracts typically require payment to Covance of expenses to wind down a study, payment
to Covance of fees earned to date, and, in some cases, a termination fee or payment to Covance of some portion of the fees or profit that could have been earned under the contract if it had not been
terminated early.

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Backlog

Some of our studies and projects are performed over an extended period of time, which may exceed several years. We maintain an order
backlog to track anticipated
net revenues for work that has yet to be earned. However, we do not maintain an order backlog for other services that are performed within a short period of time or where it is not otherwise practical
or feasible to maintain an order backlog. Our aggregate backlog at December 31, 2003 and December 31, 2002 was $1,134 million and $1,122 million, respectively.

Backlog
usually includes work to be performed under signed agreements (i.e., contracts and letters of intent). Once work under a signed agreement begins, net revenues are recognized
over the life of the project. However, in some cases we will begin work on a project once we conclude we have a legally binding agreement, but before executing a signed agreement, and backlog may
include the net revenues expected from that project.

We
cannot provide any assurance that we will be able to realize all or most of the net revenues included in backlog or estimate the portion expected to be filled in the current year.
Although backlog can provide meaningful information to our management with respect to a particular study, we believe that our aggregate backlog as of any date is not necessarily a meaningful indicator
of our future results for a variety of reasons. These reasons include the following: studies vary in duration; the scope of studies may change, which may either increase or decrease their value; and
studies may be terminated, reduced in scope or delayed at any time by the client or regulatory authorities.

Competition

The contract research organization industry has many participants ranging from hundreds of small, limited-service providers to a few full
service contract
research organizations with global capabilities. We primarily compete against in-house departments of pharmaceutical companies, full-service and limited service contract
research organizations and, to a lesser extent, with selected universities and teaching hospitals.

In
early development services our significant competitors include Charles River Laboratories International Inc., Inveresk Research Group Inc., MDS Inc., Quintiles
Transnational Corp., and PPD, Inc. among others. In late-stage development services our significant competitors include PPD, Inc., Quintiles Transnational Corp., Parexel
International Corporation, Icon PLC and Quest Diagnostics Incorporated, among others. Covance represents an important market presence in each segment's principal services.

There
is competition for customers on the basis of many factors, including the following: reputation for on-time quality performance; expertise and experience in specific
areas; scope of service offerings; strengths in various geographic markets; price; technological expertise and efficient drug development processes; ability to acquire, process, analyze and report
data in a rapid and accurate manner; historic experience and relationship ability to manage large-scale clinical trials both domestically and internationally; expertise and experience in health
economics and outcomes services; and size. We believe that we compete favorably in these areas.

Government Regulation

Our laboratory services are subject to various regulatory requirements designed to ensure the quality and integrity of the testing
processes. Covance's standard
operating procedures are written in accordance with regulations and guidelines appropriate to the region and the nation where they will be used.

The
industry standards for conducting preclinical laboratory testing are embodied in the Good Laboratory Practice (GLP) and for central laboratory operations in the Clinical Laboratory
Improvement Amendments of 1988 (CLIA). The standards of GLP are required by the FDA, by the Department of Health in the United Kingdom, by the European Agency for the Evaluation of Medical Products
(EMEA) in Europe and by similar regulatory authorities in other parts of the world. To help satisfy its compliance obligations, Covance has established quality assurance controls at its laboratory
facilities which monitor ongoing compliance with GLP and CLIA.

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Our
clinical services are subject to industry standards for the conduct of clinical research and development studies that are embodied in the regulations for Good Clinical Practice
(GCP). The FDA, EMEA and other regulatory authorities require that test results submitted to such authorities be based on studies conducted in accordance with GCP. As with GLP and Good Manufacturing
Practice (GMP), noncompliance with GCP can result in the disqualification of data collection during the clinical trial.

We
strive to perform all clinical research in accordance with the International Conference on HarmonizationGood Clinical Practice Guidelines, and the requirements of the
applicable country. Although the U.S. is a signatory to these guidelines, the FDA has not adopted all of these guidelines as statutory regulations, but has currently adopted them only as guidelines.
From an international perspective, when applicable, we have implemented common standard operating procedures across regions to assure consistency whenever it is feasible and appropriate to do so.

Our
animal import and breeding facilities are also subject to a variety of federal and state laws and regulations, including The Animal Welfare Act and the rules and regulations
promulgated thereunder by the United States Department of Agriculture ("USDA"). Our breeding and animal import facilities maintain detailed standard operating procedures and the documentation
necessary to comply with applicable regulations for the humane treatment of the animals in its custody. Besides being licensed by the USDA as both a dealer and research facility, this business is also
accredited by the Association for Assessment and Accreditation of Laboratory Animal Care International and has registered assurance with the United States National Institutes of Health Office of
Protection for Research Risks.

The
use of controlled substances in testing for drugs with a potential for abuse is regulated in the United States by the U.S. Drug Enforcement Administration. All Covance United States
laboratories using controlled substances for testing purposes are licensed by the U.S. Drug Enforcement Administration.

Our
United States laboratories are subject to licensing and regulation under federal, state and local laws relating to hazard communication and employee
right-to-know regulations, the handling and disposal of medical specimens and hazardous waste and radioactive materials, as well as the safety and health of laboratory
employees. All of our laboratories are subject to applicable federal and state laws and regulations relating to the storage and disposal of all laboratory specimens including the regulations of the
Environmental Protection Agency, the Nuclear Regulatory Commission, the Department of Transportation, the National Fire Protection Agency and the Resource Conservation and Recovery Act. Although we
believe that Covance is currently in compliance in all material respects with such federal, state and local laws, failure to comply could subject Covance to denial of the right to conduct business,
fines, criminal penalties and other enforcement actions.

In
addition to its comprehensive regulation of safety in the workplace, the Occupational Safety and Health Administration and similar regulatory authorities in foreign countries have
established extensive requirements relating to workplace safety for health care employers, whose workers may be exposed to blood-borne pathogens such as HIV and the hepatitis B virus. Covance
employees receive initial and periodic training focusing on compliance with applicable hazardous materials regulations and health and safety guidelines.

In
the past few years, both the United States and foreign governments have become more concerned about the disclosure of confidential personal data. The European Union, or EU, now
prohibits certain disclosures of personal confidential information, including medical information, to any entity that does not comply with certain security safeguards. We will continue to monitor our
compliance with applicable regulations.

The
regulations of the U.S. Department of Transportation, the U.S. Public Health Service and the U.S. Postal Service apply to the surface and air transportation of laboratory specimens.
Covance's laboratories also must comply with the applicable International Air Transport Association regulations, which govern international shipments of laboratory specimens. Furthermore, when
materials are sent to a foreign country, the transportation of such materials becomes subject to the laws, rules and regulations of such foreign country.

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Intellectual Property

We have developed certain computer software and technically derived procedures and products intended to maximize the quality and
effectiveness of our services.
Although our intellectual property rights are important to our results of operations, we believe that such factors as the technical expertise, knowledge, ability and experience of our professionals
are more important, and that, overall, these technological capabilities provide significant benefits to our clients.

Employees

At December 31, 2003, we had approximately 6,500 employees, approximately 37% of whom are employed outside of the United States and
approximately 6,000 of
whom are full time employees. Our records indicate that 64 of our employees hold M.D. degrees, 163 hold Ph.D. degrees, and 431 hold masters or other postgraduate degrees. We believe that Covance's
relations with its employees are good.

Available Information

Covance makes available free of charge on its website at www.covance.com, its Annual Report on Form 10-K, Quarterly Reports on
Form 10-Q, Current Reports on Form 8-K and amendments to those reports filed or furnished pursuant to Section 13(a) or 15(d) of the Securities Exchange Act
of 1934 as soon as reasonably practicable after such reports are electronically filed with, or furnished to, the SEC.

Item 2.    Properties

Covance both owns and leases its facilities. Covance owns substantial facilities in the United States in Madison, Wisconsin, in Vienna,
Virginia, in the United
Kingdom in Harrogate and Leeds, and in Muenster, Germany for its early development services. Covance owns a substantial facility in Geneva, Switzerland and leases a substantial facility in the United
States in Indianapolis, Indiana for its central laboratory services and leases facilities in Indianapolis, Indiana and Chantilly, Virginia for its bioanalytical services. Covance leases substantial
facilities for its clinical development services in the United States in Princeton, New Jersey, and in the United Kingdom in Maidenhead and Horsham. Covance also owns or leases other facilities in the
United States, Canada, Europe, Asia and Latin America. Covance believes that its facilities are adequate for its operations and that suitable additional space will be available when needed.

For
additional information, please see Note 11 to the audited consolidated financial statements included elsewhere in this Annual Report.

Item 3.    Legal Proceedings

Covance is party to lawsuits and administrative proceedings incidental to the normal course of its business. Covance does not believe that
any liabilities
related to such lawsuits or proceedings will have a material effect on its financial condition, results of operations or cash flows.

Item 4.    Submission of Matters to a Vote of Security Holders

None.

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PART II

Item 5.    Market for Registrant's Common Equity and Related Stockholder Matters

Covance's common stock is traded on the New York Stock Exchange (symbol: CVD). The following table shows the high and low sales prices on
the New York Stock
Exchange for each of the most recent eight fiscal quarters.

Quarter

High

LowFirst Quarter 2002

$
22.95

$
15.81Second Quarter 2002

$
21.30

$
16.81Third Quarter 2002

$
20.49

$
12.11Fourth Quarter 2002

$
25.00

$
17.90First Quarter 2003

$
27.40

$
20.75Second Quarter 2003

$
24.75

$
16.35Third Quarter 2003

$
23.10

$
17.78Fourth Quarter 2003

$
27.76

$
22.30


As
of February 11, 2004, there were 5,889 holders of record of Covance's common stock.

Covance
has not paid any dividends during 2003 or 2002. Covance does not currently intend to pay dividends, but rather, currently intends to reinvest earnings in its business. Covance
is also subject to certain restrictions on its ability to pay cash dividends on its common stock by certain covenants contained in a credit agreement to which Covance is a party.

Item 6.    Selected Financial Data

The following table presents selected historical consolidated financial data of Covance as of and for each of the years ended
December 31, 2003, 2002,
2001, 2000 and 1999. This data has been derived from the audited consolidated financial statements of Covance. You should read this selected historical consolidated financial data in conjunction with
Covance's audited consolidated financial statements and accompanying notes included elsewhere in this Annual Report. Historical consolidated financial data may not be indicative of Covance's future
performance. See also "Management's Discussion and Analysis of Financial Condition and Results of Operations."

The
information provided below is on an "as reported" basis and has not been revised to exclude the results of our biomanufacturing and packaging operations, which were divested on
June 15, 2001 and February 14, 2001, respectively. The information below also includes special charges recorded during all periods presented, as well as the net gain on sale of
businesses recorded during 2001.

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Year Ended December 312003

2002

2001

2000

1999(Dollars in thousands, except per share data)Income Statement Data:Net revenues

$
940,300

$
883,074

$
855,877
(b)
$
868,087
(b)
$
828,980Reimbursable out-of-pockets


33,910


41,623


40,167


48,298


43,093Total revenues


974,210


924,697


896,044


916,385


872,073Costs and expenses:Cost of revenue


634,722


612,465


618,119


625,595


553,283Reimbursed out-of-pocket expenses


33,910


41,623


40,167


48,298


43,093Selling, general and administrative


143,179


133,508


127,211


131,158


128,003Depreciation and amortization


45,824


42,434


47,719


54,200


48,147Special charges








8,178
(c)

12,514
(c)

12,968
(c)Total


857,635


830,030


841,394


871,765


785,494Income from operations


116,575


94,667


54,650
(d)

44,620
(d)

86,579Other expense (income), net:Interest expense, net


191


831


6,848


19,051


10,062Foreign exchange transaction losses


683


3,395


263


598


57Net gain on sale of businesses








(30,803
)(e)




Other expense (income), net


874


4,226


(23,692
)

19,649


10,119Income before taxes and equity investee earnings


115,701


90,441


78,342


24,971


76,460Taxes on income


40,021


26,658
(a)

30,442


9,735


30,642Equity investee earnings


456











Net income

$
76,136

$
63,783
(a)
$
47,900
(f)
$
15,236
(f)
$
45,818Basic earnings per share

$
1.23

$
1.06

$
0.81

$
0.27

$
0.78Diluted earnings per share

$
1.21

$
1.03
(a)
$
0.79
(f)
$
0.27
(f)
$
0.78Balance Sheet Data:Working capital

$
260,030

$
130,951

$
97,710

$
(98,710
)
$
102,247Total assets

$
807,625

$
677,003

$
612,028

$
771,091

$
689,721Long-term debt

$


$


$
15,000

$
17,224

$
208,724Stockholders' equity

$
563,981

$
431,667

$
344,945

$
265,751

$
252,059Other Financial Data:Gross margin


32.5
%

30.6
%

27.8
%

27.9
%

33.3
%Operating margin


12.4
%

10.7
%

6.4
%

5.1
%

10.4
%Net income margin


8.1
%

7.2
%

5.6
%

1.8
%

5.5
%Current ratio


2.37


1.61


1.43


0.78


1.51Debt to capital


0.00


0.00


0.04


0.49


0.48Book value per share


9.02


7.13


5.77


4.60


4.42Net days sales outstanding


45


41


41


54


52


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Item 7.    Management's Discussion and Analysis of Financial Condition and Results of Operations

Overview

Covance is a leading drug development services company providing a wide range of early stage and late stage product development services
on a worldwide basis
primarily to the pharmaceutical, biotechnology and medical device industries. Covance also provides services such as laboratory testing to the chemical, agrochemical and food industries. The foregoing
services comprise two reportable segments for financial reporting purposes: early development services, which includes preclinical and Phase I clinical service offerings; and late-stage
development services, which includes central laboratory, clinical development, periapproval, central ECG diagnostic services, and health care economic and reimbursement services. Although each segment
has separate services within it, they can be combined in joint service
offerings and we believe clients increasingly are interested in the opportunities for such combined services. Covance believes it is one of the largest drug development services companies, based on
annual net revenues, and one of a few that is capable of providing comprehensive global product development services. Covance offers its clients high quality services designed to provide data to
clients as rapidly as possible and reduce product development time. We believe this enables Covance's customers to introduce their products into the marketplace faster and as a result, maximize the
period of market exclusivity and monetary return on their research and development investments. Additionally, Covance's comprehensive services and broad experience provide its customers with a
variable cost alternative to fixed cost internal development capabilities.

Critical Accounting Policies

Covance's consolidated financial statements are prepared in accordance with accounting principals generally accepted in the United States
("GAAP"), which require
management to make estimates and assumptions about future events that affect the amounts reported in the financial statements and the accompanying notes. Actual results could differ from these
estimates. The following discussion highlights what we believe to be the critical accounting policies and judgments made in the preparation of these consolidated financial statements.

Revenue Recognition.Covance recognizes revenue either as services are performed
or products are
delivered, depending upon the nature of the work contracted. Historically, a majority of Covance's net revenues have been earned under contracts which range in duration from a few months to two years,
but can extend in duration up to five years or longer. Service contracts generally take the form of fee-for-service or fixed-price arrangements. In the case of
fee-for-service contracts, revenue is recognized as services are performed, based upon, for example, hours worked or samples tested. For long-term fixed-price
service contracts, revenue is recognized as services are performed, with performance generally assessed using output measures, such as units-of-work performed to date as
compared to the total units-of-work contracted. Changes in the scope of work generally result in a renegotiation of contract pricing terms. Renegotiated amounts are not
included in net revenues until earned and realization is assured. Estimates of costs to complete are made to provide, where appropriate, for losses expected on contracts. Costs are not deferred in
anticipation of contracts being awarded, but instead are expensed as incurred. In some cases, for multi-year contracts, a portion of the contract fee is paid at the time the trial is
initiated. These advances are deferred and recognized as revenue as services are performed, as discussed above. Additional payments may be made based upon the achievement of performance-based
milestones over the contract duration. Most contracts are terminable by the client either immediately or upon notice. These contracts typically require payment to Covance of expenses to wind down the
study, fees earned to date and, in some cases, a termination fee or a payment to Covance of some portion of the fees or profits that could have been earned by Covance under the contract if it had not
been terminated early. Termination fees are included in net revenues when realization is assured.

Bad Debts.Covance endeavors to assess and monitor the creditworthiness of its
customers to which it
grants credit terms in the ordinary course of business. Covance maintains a provision for doubtful accounts to provide for the possibility that amounts due Covance may not be collected. This bad debt
provision is monitored on a monthly basis and adjusted as circumstances warrant. Since the recorded bad debt provision is

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based
upon management's judgment, actual bad debt write-offs may be greater or less than the amount recorded. Historically bad debt write-offs have not been material.

Taxes on Income.Since Covance conducts operations on a global basis, its
effective tax rate has and
will continue to depend upon the geographic distribution of its pre-tax earnings among locations with varying tax rates. Covance's profits are further impacted by changes in the tax rates
of the various jurisdictions. In particular, as the geographic mix of Covance's pre-tax earnings among various tax jurisdictions changes, Covance's effective tax rate may vary from period
to period. Covance has established, and periodically reevaluates, an estimated income tax reserve on its consolidated balance sheet to provide for the possibility of adverse outcomes in income tax
proceedings. While Covance believes that it has identified all reasonably identifiable exposures and that the reserve it has established for identifiable exposures is appropriate under the
circumstances, it is possible that additional exposures exist and that exposures will be settled at amounts different than the amounts reserved. It is possible that changes in estimates in the future
could cause Covance to either materially increase or reduce the carrying amount of its income tax reserve. In addition, Covance's policy is to provide income taxes on earnings of foreign subsidiaries
to the extent those earnings are taxable or are expected to be remitted. Taxes have not been provided on accumulated foreign unremitted earnings totaling $127.0 million as of
December 31, 2003 because Covance currently intends to leave these earnings invested in those countries. If Covance were to repatriate these earnings, or a portion of these earnings, Covance
might incur a significant income tax liability.

Stock Based Compensation.Covance grants stock options to its employees at an
exercise price equal
to the fair value of the shares at the date of grant and accounts for these stock option grants in accordance with APB Opinion No. 25,Accounting for Stock Issued to
Employees("APB 25") and related interpretations. Under APB 25, when stock options are issued with an exercise price equal to the market price of the underlying stock on the
date of grant, no compensation expense is recognized in the income statement.

Impairment of Assets.Covance reviews its long-lived assets for impairment, when
events
or changes in circumstances occur that indicate that the carrying value of the asset may not be recoverable. The assessment of possible impairment is based upon Covance's judgment of its ability to
recover the asset from the expected future undiscounted cash flows of the related operations. Actual future cash flows may be greater or less than estimated.

Covance
performs an annual test for impairment of goodwill. This test is performed by comparing, at the reporting unit level, the carrying value of goodwill to its fair value. Covance
assesses fair value based upon its best estimate of the present value of the future cash flows that it expects to be generated by the reporting unit. The test performed for 2003 did not identify any
instances of impairment. However, changes in expectations as to the present value of the reporting unit's future cash flows might impact subsequent years' assessments of impairment.

Defined Benefit Pension Plans.Covance sponsors defined benefit pension plans for
the benefit of its
employees at three foreign subsidiaries. The measurement of the related pension benefit obligation and the expense recorded in each year is based upon actuarial computations which require judgment as
to (a) the appropriate discount rate to use in computing the present value of the benefit obligation, (b) the expected return on plan assets and (c) the expected future rate of
salary increases. Actual results will likely differ, in some periods materially, from the assumptions used in the actuarial valuation.

Foreign Currency Risks

Since Covance operates on a global basis, it is exposed to various foreign currency risks. Two specific risks arise from the nature of the
contracts Covance
executes with its customers since from time to time contracts are denominated in a currency different than the particular Covance subsidiary's local currency. These risks are generally applicable only
to a portion of the contracts executed by Covance's foreign subsidiaries providing clinical services. The first risk occurs as revenue recognized for services rendered is denominated in a currency
different from the currency in which the subsidiary's expenses are incurred. As a

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result,
the subsidiary's net revenues and resultant earnings can be affected by fluctuations in exchange rates. Historically, fluctuations in exchange rates from those in effect at the time contracts
were executed have not had a material effect upon Covance's consolidated financial results. See "Risk Factors".

The
second risk results from the passage of time between the invoicing of customers under these contracts and the ultimate collection of customer payments against such invoices. Because
the contract is denominated in a currency other than the subsidiary's local currency, Covance recognizes a receivable at the time of invoicing for the local currency equivalent of the foreign currency
invoice amount. Changes in exchange rates from the time the invoice is prepared and payment from the customer is received will result in Covance receiving either more or less in local currency than
the local currency equivalent of the invoice amount at the time the invoice was prepared and the receivable established. This difference is recognized by Covance as a foreign currency transaction gain
or loss, as applicable, and is reported in other expense (income) in Covance's Consolidated Statements of Income. Foreign currency transaction losses for the year ended December 31, 2003 were
$0.7 million.

Finally,
Covance's consolidated financial statements are denominated in U.S. dollars. Accordingly, changes in exchange rates between the applicable foreign currency and the U.S. dollar
will affect the translation of each foreign subsidiary's financial results into U.S. dollars for purposes of reporting Covance's consolidated financial results. The process by which each foreign
subsidiary's financial results are translated into U.S. dollars is as follows: income statement accounts are translated at average exchange rates for the period; balance sheet asset and liability
accounts are translated at end of period exchange rates; and equity accounts are translated at historical exchange rates. Translation of the balance sheet in this manner affects the stockholders'
equity account, referred to as the cumulative translation adjustment account. This account exists only in the foreign subsidiary's U.S. dollar balance sheet and is necessary to keep the foreign
balance sheet stated in U.S. dollars in balance. To date such cumulative translation adjustments have not been material to Covance's consolidated financial position.

Operating Expenses and Reimbursable Out-of-Pockets

Covance segregates its recurring operating expenses among four categories: cost of revenue; reimbursed out-of-pocket expenses; selling,
general and administrative expenses; and depreciation and amortization. Cost of revenue includes direct labor and related benefits, other direct costs, shipping and handling fees, and an allocation of
facility charges and information technology costs, and excludes depreciation and amortization. Cost of revenue, as a percentage of net revenues, tends and is expected to fluctuate from one period to
another, as a result of changes in labor utilization and the mix of service offerings involving hundreds of studies conducted during any period of time. Selling, general and administrative expenses
consist primarily of administrative payroll and related benefit charges, advertising and promotional expenses, administrative travel and an allocation of facility charges and information technology
costs, and excludes depreciation and amortization.

In
connection with the management of multi-site clinical trials, Covance pays on behalf of its customers fees to investigators, volunteers and other
out-of-pocket costs (such as for travel, printing, meetings, couriers, etc.), for which it is reimbursed at cost, without mark-up or profit. Investigator fees are
not reflected in total revenues or expenses where Covance acts in the capacity of an agent on behalf of the pharmaceutical company sponsor, passing through these costs without risk or reward to
Covance. All other out-of-pocket costs are included in total revenues and expenses.

Results of Operations

Year Ended December 31, 2003 Compared with Year Ended December 31, 2002.Net revenues
increased 6.5% to $940.3 million for 2003 from $883.1 million for 2002. Excluding the impact of foreign exchange rate variances between both periods, net revenues increased 2.8% as
compared to 2002. Net revenues from Covance's early development segment grew 11.9%, or 8.2% excluding the impact of foreign exchange rate variances between both periods, on strong performance in our
North American and European toxicology,

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chemistry
and Phase I clinical services. Net revenues from Covance's late-stage development segment increased 2.6%, but decreased 1.1% excluding the impact of foreign exchange rate
variances between both periods. Growth in our late-stage development segment was negatively impacted by a shift in the mix of our Phase IV backlog to longer-term studies which
negatively affected current period net revenues, and also due to weak first half 2003 net orders in our central laboratory.

Cost
of revenue increased 3.6% to $634.7 million or 67.5% of net revenues for the year ended December 31, 2003 as compared to $612.5 million or 69.4% of net
revenues for the corresponding 2002 period. Gross margins improved 190 basis points to 32.5% for the year ended December 31, 2003 from 30.6% for the corresponding 2002 period, on process
improvements and cost controls, especially in our central laboratory and across most of our early development service offerings.

Overall,
selling, general and administrative expenses increased 7.2% to $143.2 million for 2003 from $133.5 million for 2002. As a percentage of net revenues, selling,
general and administrative expenses increased 10 basis points to 15.2% for 2003 from 15.1% for 2002.

Depreciation
and amortization increased 8.0% to $45.8 million or 4.9% of net revenues for 2003 from $42.4 million or 4.8% of net revenues for 2002.

Income
from operations increased 23.1% to $116.6 million or 12.4% of net revenues for 2003 from $94.7 million or 10.7% of net revenues for the corresponding 2002 period.
Income from operations from Covance's early development segment increased $16.6 million or 24.9% to $83.3 million or 20.3% of net revenues for the year ended December 31, 2003
from $66.7 million or 18.1% of net revenues for the corresponding 2002 period, primarily driven by strong performance in our North American and European toxicology, chemistry, and Phase I
services. Income from operations from Covance's late-stage development segment increased $6.2 million or 8.6% to $79.2 million or 15.0% of net revenues for 2003 from
$73.0 million or 14.2% of net revenues for the corresponding 2002 period, primarily driven by process improvements in our central laboratory and clinical development services, partially offset
by softness in our Phase IV service offering from lower revenues. Corporate expense increased $1.0 million to $46.0 million or 4.9% of net revenues for 2003 from $45.0 million or
5.1% of net revenues for 2002.

Other
expense, net decreased $3.4 million to $0.9 million for 2003 from $4.2 million for 2002. The weakening of the U.S. dollar during the year ended
December 31, 2002 drove foreign exchange transaction losses totaling $3.4 million as compared to losses totaling only $0.7 million for the comparable 2003 period. Also
contributing to the decrease was a $0.6 million reduction in net interest expense.

Covance's
effective tax rate for the year ended December 31, 2003 was 34.6% as compared to 29.5% for the corresponding 2002 period. Covance's 2002 effective tax rate reflects the
reversal of a $6.5 million income tax reserve relating primarily to the favorable settlement of a longstanding multi-year foreign income tax audit. Excluding the effect of this
adjustment, Covance's effective tax rate for the year ended December 31, 2002 was 36.7%. The 210 basis point reduction in Covance's effective tax rate during 2003 (excluding this 2002
adjustment) is attributable to a number factors, including the mix of our pre-tax earnings across various tax jurisdictions, recently enacted research and development tax credits in the
United Kingdom, and other initiatives.

Covance
has a minority equity position (approximately 22% at December 31, 2003) in Bio-Imaging Technologies, Inc. ("BITI"). BITI uses proprietary medical
imaging technologies to process and analyze medical images, and also provides other services, including the data-basing and regulatory submission of medical images, quantitative data and
text. During
the year ended December 31, 2003, Covance recognized income of $0.5 million, representing its pro rata share of BITI's earnings.

Net
income of $76.1 million for the year ended December 31, 2003 increased $12.4 million or 19.4% as compared to $63.8 million for the corresponding 2002
period. Excluding the $6.5 million income tax reserve reversal discussed above, net income increased $18.9 million or 32.9% as compared to the corresponding 2002 period.

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Year Ended December 31, 2002 Compared with Year Ended December 31, 2001.The following
table presents the results for the years ended December 31, 2002 and 2001 on both a GAAP and a pro forma basis. The presentation of pro forma results is intended to assist the reader in
analyzing the results for the periods on what management believes to be a more comparable (i.e., like-on-like) basis. Pro forma adjustments have been made 1) for a
$6.5 million reduction in our income tax reserve and provision recorded in 2002, 2) to reflect the sale of our packaging and biomanufacturing operations as if these transactions had
occurred on January 1, 2001, 3) for a restructuring charge totaling $8.2 million ($5.0 million net of tax) recorded in 2001, and 4) for goodwill amortization in 2001
totaling $3.6 million ($2.9 million net of tax), in accordance with the adoption of Statement of Financial Accounting Standards ("SFAS") No. 142,Goodwill
and Other Intangible Assets.

|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|----------------------------------- |  | - | ------- | - | - | ------ | - | - | ------- | - | - | ------- | - | - | ------- | - | - | ----- |  | - | ----- |  | - | ------- | -
|
|
|
|
|Net revenues:                       |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|Early Development                   |  | $ | 367,542 |   | $ |       |   | $ | 367,542 |   | $ | 311,143 |   | $ |        |   | $ |      |  | $ |      |  | $ | 311,143 |  
|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|Late-stage Development              |  |   | 515,532 |   |   |       |   |   | 515,532 |   |   | 544,734 |   |   | (55,612 | ) |   |      |  |   |      |  |   | 489,122 |  
|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|Total net revenues                  |  |   | 883,074 |   |   |       |   |   | 883,074 |   |   | 855,877 |   |   | (55,612 | ) |   |      |  |   |      |  |   | 800,265 |  
|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|Cost of revenue                     |  |   | 612,465 |   |   |       |   |   | 612,465 |   |   | 618,119 |   |   | (44,049 | ) |   |      |  |   |      |  |   | 574,070 |  
|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|Selling, general and administrative |  |   | 133,508 |   |   |       |   |   | 133,508 |   |   | 127,211 |   |   | (4,478  | ) |   |      |  |   |      |  |   | 122,733 |  
|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|Depreciation and amortization       |  |   | 42,434  |   |   |       |   |   | 42,434  |   |   | 47,719  |   |   | (4,768  | ) |   |      |  |   | 3,551 |  |   | 46,502  |  
|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|Income from operations:             |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|Early Development                   |  |   | 66,682  |   |   |       |   |   | 66,682  |   |   | 47,963  |   |   |        |   |   | 586   |  |   | 524   |  |   | 49,073  |  
|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|Late-stage Development              |  |   | 72,979  |   |   |       |   |   | 72,979  |   |   | 33,166  |   |   | (2,317  | ) |   | 7,592 |  |   | 3,027 |  |   | 41,468  |  
|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|Corporate expenses                  |  |   | (44,994 | ) |   |       |   |   | (44,994 | ) |   | (26,479 | ) |   |        |   |   |      |  |   |      |  |   | (26,479 | )
|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|Total income from operations        |  |   | 94,667  |   |   |       |   |   | 94,667  |   |   | 54,650  |   |   | (2,317  | ) |   | 8,178 |  |   | 3,551 |  |   | 64,062  |  
|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|Other expense (income), net         |  |   | 4,226   |   |   |       |   |   | 4,226   |   |   | (23,692 | ) |   | 26,095  |   |   |      |  |   |      |  |   | 2,403   |  
|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  
|Net income                          |  | $ | 63,783  |   | $ | (6,500 | ) | $ | 57,283  |   | $ | 47,900  |   | $ | (17,716 | ) | $ | 4,985 |  | $ | 2,858 |  | $ | 38,027  |  
|                                    |  |   |         |   |   |        |   |   |         |   |   |         |   |   |         |   |   |       |  |   |       |  |   |         |  

Net revenues increased 3.2% to $883.1 million for 2002 from $855.9 million for 2001. The 2001 period includes revenues from
Covance's biomanufacturing operations through June 15, 2001 and revenues from Covance's packaging operations through February 14, 2001 which aggregated $55.6 million. On a pro
forma basis, net revenues increased $82.8 million or 10.3% from $800.3 million for 2001. Excluding the impact of foreign exchange rate variances between both periods, net revenues
increased 8.5% on a pro forma basis, as compared to 2001. Net revenues from Covance's early development segment grew 18.1%, or 16.6% excluding the impact of foreign exchange rate variances between
both periods, driven primarily by growth in our toxicology service offering. On a GAAP basis, revenue from Covance's late-stage
development segment declined $29.2 million or 5.4% to $515.5 million from $544.7 million. On a pro forma basis, excluding the net revenues from the businesses divested in 2001,
net revenues from Covance's late-stage development segment increased 5.4%, or 3.4% excluding the impact of foreign exchange rate variances between both periods. The modest
late-stage development revenue growth, in part, resulted from our strategy to first improve our operating margins by an increased focus on contract selectivity in our Phase II/III
services, and the slower conversion of our backlog to revenue in our central laboratory business during the first half of 2002.

Cost
of revenue, decreased 0.9% to $612.5 million or 69.4% of net revenues for the year ended December 31, 2002 as compared to $618.1 million or 72.2% of net
revenues for the corresponding 2001 period. Gross margins were 30.6% for the year ended December 31, 2002, up from 27.8% for the corresponding 2001 period. The 2001 period includes cost of
revenue from Covance's biomanufacturing and packaging operations totaling $44.0 million. On a pro forma basis, cost of revenue in 2001 totaled $574.1 million and gross margins were
28.3%. Also, the 2001 period includes higher investment spending on internet initiatives and lower margins on bioanalytical services.

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Overall, selling, general and administrative expenses increased 5.0% to $133.5 million for 2002 from $127.2 million for 2001. As a percentage of
net revenues, selling,
general and administrative expenses increased to 15.1% for 2002 from 14.9% for 2001. The 2001 period includes selling, general and administrative expenses from Covance's biomanufacturing and packaging
operations totaling $4.5 million. On a pro forma basis, selling, general and administrative expenses for the 2001 period totaled $122.7 million, or 15.3% of net revenues.

Depreciation
and amortization decreased 11.1% to $42.4 million or 4.8% of net revenues for 2002 from $47.7 million or 5.6% of net revenues for 2001, due primarily to the
divestiture of our capital intensive biomanufacturing and packaging businesses in the first half of 2001, and the implementation of SFAS No. 142 in the first quarter of 2002, which has
eliminated the amortization of goodwill. Depreciation and amortization from our divested biomanufacturing and packaging operations included in the 2001 period totaled $4.8 million. Goodwill
amortization included in the 2001 period totaled $3.6 million. On a pro forma basis, depreciation and amortization increased 7.7% over 2001.

Income
from operations increased 73.2% to $94.7 million for 2002 from $54.7 million for the corresponding 2001 period. Income from operations from Covance's early
development segment increased $18.7 million or 39.0% to $66.7 million or 18.1% of net revenues for the year ended December 31, 2002 from $48.0 million or 15.4% of net
revenues for the corresponding 2001 period, primarily driven by growth in our toxicology services offering. Income from operations from Covance's late-stage development segment increased
$39.8 million or 120.0% to $73.0 million or 14.2% of net revenues for 2002 from $33.2 million or 6.1% of net revenues for the corresponding 2001 period. Corporate expenses
increased $18.5 million to $45.0 million or 5.1% of net revenues for 2002 from $26.5 million or 3.3% of net revenues for 2001. The increase is primarily attributable to the
centralization of information technology infrastructure in 2002 and investments made therein, increased marketing and higher variable compensation expenses.

The
2001 period includes income from operations from our divested biomanufacturing and packaging operations totaling $2.3 million, a restructuring charge totaling
$8.2 million and goodwill amortization totaling $3.6 million. On a pro forma basis, income from operations increased 47.8% to $94.7 million for 2002 from $64.1 million for
2001. As a percentage of net revenues on a pro forma basis, income from operations increased to 10.7% for 2002 from 8.0% for 2001. On a pro forma basis, income from operations from Covance's early
development segment increased $17.6 million or 35.9% to $66.7 million, as compared to $49.1 million for 2001. On a pro forma basis, income from operations from Covance's
late-stage development segment increased $31.5 million or 76.0% to $73.0 million as compared to $41.5 million for 2001, primarily driven by growth in our toxicology
service offering. The increase in late-stage development operating income on a pro forma basis was due to Covance's continued focus on margin improvements in our Phase II/III services,
increased volume in our Phase III and central laboratory services during the second half of 2002, and margin growth in our commercialization services.

Other
expense, net for the year ended December 31, 2002 totaled $4.2 million as compared to other income, net for the 2001 period totaling $23.7 million. Other
income, net for the 2001 period includes a $30.8 million net pre-tax gain on the sale of our packaging and biomanufacturing operations, offset by interest expense totaling
$4.7 million related to these divested businesses. On a pro forma basis, other expense, net increased $1.8 million to $4.2 million for 2002 from $2.4 million for 2001, due
primarily to a $0.7 million reduction in interest expense resulting from lower weighted average borrowings under our long-term credit facility, partially offset by a
$3.1 million increase in foreign exchange transaction losses, as a result of the weakening U.S. dollar.

Covance's
effective tax rate for the year ended December 31, 2002 was 29.5% as compared to 38.9% for the corresponding 2001 period. Covance's 2002 effective tax rate reflects the
reversal of a $6.5 million income tax reserve due to a change in estimate relating primarily to the favorable settlement of a longstanding multi-year foreign income tax audit.
Excluding the effect of this adjustment, Covance's effective tax rate for the year ended December 31, 2002 was 36.7%. The pro forma effective tax rate for the 2001 period was 38.3%.

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Net
income was $63.8 million for the year ended December 31, 2002 versus $47.9 million for 2001. Net income for the 2001 period includes the net
after-tax impact from the divestiture of our biomanufacturing and packaging operations totaling $17.7 million; the after-tax impact of a restructuring charge totaling
$5.0 million; and the after-tax impact of goodwill amortization totaling $2.9 million. On a pro forma basis, net income increased 50.6% or $19.3 million to
$57.3 million for the year ended December 31, 2002 as compared to $38.0 million for the corresponding 2001 period.

Quarterly Results

Covance's quarterly operating results are subject to variation, and are expected to continue to be subject to variation, as a result of
factors such as
(1) delays in initiating or completing significant drug development trials, (2) termination or reduction in size of drug development trials, (3) acquisitions and divestitures, and
(4) exchange rate fluctuations. Delays and terminations of trials are often the result of actions taken by Covance's customers or regulatory authorities and are not typically controllable by
Covance. Since a large amount of Covance's operating costs are relatively fixed while revenue is subject to fluctuation, moderate variations in the commencement, progress or completion of drug
development trials may cause significant variations in quarterly results.

The
following table presents unaudited quarterly operating results of Covance for each of the eight most recent fiscal quarters during the period ended December 31, 2003. In the
opinion of Covance, the information in the table below has been prepared on the same basis as the audited consolidated financial statements included elsewhere in this Annual Report and reflects all
adjustments (consisting only of normal recurring adjustments) necessary for a fair presentation of results of operations for those periods. This quarterly financial data should be read in conjunction
with the audited consolidated financial statements included elsewhere in this Annual Report. Operating results for any quarter are not necessarily indicative of the results that may be reported in any
future period.

|                                    |  |   |         |  |   |         |  |   |         |  |   |         |  |   |         |  |   |          |   |   |         |  |   |         | 
|----------------------------------- |  | - | ------- |  | - | ------- |  | - | ------- |  | - | ------- |  | - | ------- |  | - | -------- | - | - | ------- |  | - | ------- | 
|
|
|
|                                    |  |   |         |  |   |         |  |   |         |  |   |         |  |   |         |  |   |          |   |   |         |  |   |        
|Net revenues                        |  | $ | 241,112 |  | $ | 231,954 |  | $ | 233,838 |  | $ | 233,396 |  | $ | 234,318 |  | $ | 220,968  |   | $ | 219,206 |  | $ | 208,582
|Reimbursable out-of-pockets         |  |   | 7,853   |  |   | 7,897   |  |   | 8,507   |  |   | 9,653   |  |   | 11,376  |  |   | 9,924    |   |   | 10,623  |  |   | 9,700  
|                                    |  |   |         |  |   |         |  |   |         |  |   |         |  |   |         |  |   |          |   |   |         |  |   |        
|Total revenues                      |  |   | 248,965 |  |   | 239,851 |  |   | 242,345 |  |   | 243,049 |  |   | 245,694 |  |   | 230,892  |   |   | 229,829 |  |   | 218,282
|                                    |  |   |         |  |   |         |  |   |         |  |   |         |  |   |         |  |   |          |   |   |         |  |   |        
|Costs and expenses:                 |  |   |         |  |   |         |  |   |         |  |   |         |  |   |         |  |   |          |   |   |         |  |   |        
|Cost of revenue                     |  |   | 161,205 |  |   | 154,789 |  |   | 157,708 |  |   | 161,020 |  |   | 159,541 |  |   | 152,568  |   |   | 152,297 |  |   | 148,059
|Reimbursed out-of-pocket expenses   |  |   | 7,853   |  |   | 7,897   |  |   | 8,507   |  |   | 9,653   |  |   | 11,376  |  |   | 9,924    |   |   | 10,623  |  |   | 9,700  
|Selling, general and administrative |  |   | 36,928  |  |   | 36,109  |  |   | 36,522  |  |   | 33,620  |  |   | 34,827  |  |   | 33,201   |   |   | 34,215  |  |   | 31,265 
|Depreciation and amortization       |  |   | 11,950  |  |   | 11,263  |  |   | 11,452  |  |   | 11,159  |  |   | 11,794  |  |   | 10,329   |   |   | 10,205  |  |   | 10,106 
|                                    |  |   |         |  |   |         |  |   |         |  |   |         |  |   |         |  |   |          |   |   |         |  |   |        
|Total                               |  |   | 217,936 |  |   | 210,058 |  |   | 214,189 |  |   | 215,452 |  |   | 217,538 |  |   | 206,022  |   |   | 207,340 |  |   | 199,130
|                                    |  |   |         |  |   |         |  |   |         |  |   |         |  |   |         |  |   |          |   |   |         |  |   |        
|Income from operations              |  |   | 31,029  |  |   | 29,793  |  |   | 28,156  |  |   | 27,597  |  |   | 28,156  |  |   | 24,870   |   |   | 22,489  |  |   | 19,152 
|Other expense (income), net         |  |   | 329     |  |   | 340     |  |   | 111     |  |   | 94      |  |   | 1,562   |  |   | 801      |   |   | 1,689   |  |   | 174    
|                                    |  |   |         |  |   |         |  |   |         |  |   |         |  |   |         |  |   |          |   |   |         |  |   |        
|Income before taxes                 |  |   | 30,700  |  |   | 29,453  |  |   | 28,045  |  |   | 27,503  |  |   | 26,594  |  |   | 24,069   |   |   | 20,800  |  |   | 18,978 
|Taxes on income                     |  |   | 10,363  |  |   | 10,035  |  |   | 9,861   |  |   | 9,762   |  |   | 9,574   |  |   | 2,186(a  | ) |   | 7,698   |  |   | 7,200  
|Equity investee earnings            |  |   | 117     |  |   | 92      |  |   | 70      |  |   | 177     |  |   |        |  |   |         |   |   |        |  |   |       
|                                    |  |   |         |  |   |         |  |   |         |  |   |         |  |   |         |  |   |          |   |   |         |  |   |        
|Net income                          |  | $ | 20,454  |  | $ | 19,510  |  | $ | 18,254  |  | $ | 17,918  |  | $ | 17,020  |  | $ | 21,883(a | ) | $ | 13,102  |  | $ | 11,778 
|                                    |  |   |         |  |   |         |  |   |         |  |   |         |  |   |         |  |   |          |   |   |         |  |   |        
|Basic earnings per share            |  |   | $0.33   |  |   | $0.32   |  |   | $0.30   |  |   | $0.29   |  |   | $0.28   |  |   | $0.36(a  | ) |   | $0.22   |  |   | $0.20  
|Diluted earnings per share          |  |   | $0.32   |  |   | $0.31   |  |   | $0.29   |  |   | $0.28   |  |   | $0.27   |  |   | $0.36(a  | ) |   | $0.21   |  |   | $0.19  
|                                    |  |   |         |  |   |         |  |   |         |  |   |         |  |   |         |  |   |          |   |   |         |  |   |        

---

17

---

Liquidity and Capital Resources

Covance has a centralized domestic cash management function whereby cash received from operations is generally swept daily to a centrally
managed concentration
account. Cash disbursements for operations are funded as needed from the concentration account. From time to time excess cash balances are maintained at Covance, generally for specific cash
requirements.

Covance's
expected primary cash needs on both a short and long-term basis are for capital expenditures, expansion of services, possible future acquisitions, geographic
expansion, working capital and other general corporate purposes, including possible share repurchases. Covance believes cash from operations will provide sufficient liquidity for the foreseeable
future. In addition, Covance has access to additional cash through its $150 million senior revolving credit facility (the "Credit Facility"). Although the Credit Facility expires in
June 2004, Covance is confident that should it decide to enter into a replacement credit facility, it will be able to do so on satisfactory terms. At December 31, 2003, there were no
outstanding borrowings and $2.2 million of outstanding letters of credit under the Credit Facility. At December 31, 2003, Covance has a remaining availability under the Credit Facility
of $147.8 million of which $22.8 million remains available for letters of credit. Interest on all outstanding borrowings under the Credit Facility is based upon the London Interbank
Offered Rate ("LIBOR") plus a margin. Costs associated with
replacing the previous credit facility in June 2001, consisting primarily of bank fees totaling $1.7 million, are being amortized to interest expense over the three year facility term.
The Credit Facility contains various covenants, which among other things, restrict certain uses of cash such as certain restrictions on its ability to pay cash dividends on the Covance common stock.
At December 31, 2003, Covance was in compliance with the terms of its Credit Facility. Commitment fees for the year ended December 31, 2003 under the Credit Facility were
0.5 percent of the undrawn balance of the Credit Facility and approximated $0.8 million. The Credit Facility is collateralized by guarantees of certain of Covance's domestic subsidiaries
and a pledge of 65 percent of the capital stock of certain of Covance's foreign subsidiaries.

As
discussed in Note 11 to the audited consolidated financial statements included elsewhere in this Annual Report, and as set forth in the table below, Covance is obligated under
non-cancelable operating leases, primarily for its offices and laboratory facilities. Covance is also obligated under outsourcing agreements related to certain aspects of its information
technology and human resources support functions, which is reflected as purchase obligations in the table below. Actual amounts paid under these outsourcing agreements could be higher or lower than
the amounts shown below as a result of changes in volume and other variables. In addition, early termination of these outsourcing agreements by Covance could result in the payment of termination fees
which are not reflected in the table below.

|                     |  |   |         |  |   |        |  |   |        |  |   |        |  |   |        | 
|-------------------- |  | - | ------- |  | - | ------ |  | - | ------ |  | - | ------ |  | - | ------ | 
|
|
|
|                     |  |   |         |  |   |        |  |   |        |  |   |        |  |   |       
|Operating Leases     |  | $ | 137,575 |  | $ | 27,568 |  | $ | 36,003 |  | $ | 27,451 |  | $ | 46,553
|Purchase Obligations |  |   | 172,743 |  |   | 26,533 |  |   | 59,556 |  |   | 47,361 |  |   | 39,293
|                     |  |   |         |  |   |        |  |   |        |  |   |        |  |   |       
|Total                |  | $ | 310,318 |  | $ | 54,101 |  | $ | 95,559 |  | $ | 74,812 |  | $ | 85,846
|                     |  |   |         |  |   |        |  |   |        |  |   |        |  |   |       
|                     |  |   |         |  |   |        |  |   |        |  |   |        |  |   |       

During
the year ended December 31, 2003, Covance's operations provided net cash of $140.2 million, an increase of $16.3 million from the corresponding 2002 period.
The change in net operating assets used $11.7 million in cash during 2003, primarily due to a decrease in accrued liabilities and unearned revenue, while this net change used
$12.7 million in cash during 2002, primarily due to a decrease in unearned revenue. Covance's ratio of current assets to current liabilities was 2.37 at December 31, 2003 and 1.61 at
December 31, 2002.

18

---

Investing
activities for the year ended December 31, 2003 used $62.6 million compared to using $69.6 million for the corresponding 2002 period. Capital spending for
2003 totaled $62.6 million, and included the purchase of our previously leased Geneva facility in September 2003 for $18.8 million, expansion and enhancement of our Harrogate,
England facility, outfitting of new facilities, purchase of new equipment,
upgrade of existing equipment and computer equipment and software for newly hired employees. Capital spending for the corresponding 2002 period totaled $66.8 million, and was primarily for the
expansion of Covance's toxicology capacity, outfitting of new facilities, purchase of new equipment, upgrade of existing equipment and computer equipment and software for newly hired employees.
Investing activities for 2002 also include the July 2002 acquisition of Virtual Central Laboratory b.v. for a gross cash payment of $3.0 million.

Financing
activities for the year ended December 31, 2003 provided $11.8 million and consisted primarily of $27.7 million received from stock option exercises and
employee contributions to Covance's noncompensatory employee stock purchase plan, partially offset by the purchase into treasury of 722,209 shares of common stock for an aggregate cost of
$15.9 million, primarily in connection with a 3.0 million share buyback program authorized by Covance's Board of Directors in February 2003. Financing activities for the year
ended December 31, 2002 used $17.8 million for the purchase into treasury of 1,024,550 shares of common stock for an aggregate cost of $16.6 million, primarily pursuant to a Board
of Directors authorized 3,000,000 share buyback program, and repayments under the Credit Facility totaling $15.0 million, offset by $13.9 million received from stock option exercises and
employee contributions to Covance's noncompensatory employee stock purchase plan.

At
December 31, 2003, Covance's cash balances increased by $95.7 million to $171.6 million from $75.9 million at December 31, 2002.

Inflation

While most of Covance's net revenues are earned under contracts, the long-term contracts (those in excess of one year) generally include
an inflation
or cost of living adjustment for the portion of the services to be performed beyond one year from the contract date. As a result, Covance believes that the effects of inflation generally do not have a
material effect on its operations or financial condition.

Forward Looking Statements.Statements in this Management's Discussion and Analysis of Financial Condition and Results of Operations, as
well as in certain other parts of this Annual Report on Form 10-K that look forward in time, are forward looking statements made pursuant to the safe harbor provisions of the
Private Securities Litigation Reform Act of 1995. Forward looking statements include statements concerning plans, objectives, goals, strategies, future events or performance, expectations,
predictions, and assumptions and other statements which are other than statements of historical facts. All such forward looking statements are based on the current expectations of management and are
subject to, and are qualified by, risks and uncertainties that could cause actual results to differ materially from those expressed or implied by those statements. These risks and uncertainties
include, without limitation, competitive factors, outsourcing trends in the pharmaceutical industry, levels of industry research and development spending, the Company's ability to continue to attract
and retain qualified personnel, the fixed price nature of contracts or the loss of large contracts, risks associated with acquisitions and investments, the Company's ability to increase profitability
of its clinical development services and to increase order volume in central laboratory and commercialization services, and continued growth in demand for bioanalytical services and Covance's ability
to provide these services on a large scale basis, and other factors described in Covance's filings with the Securities and Exchange Commission, including, without limitation, this Annual Report on
Form 10-K.

Risk Factors

This section discusses various risk factors that are attendant with our business and the provision of our services. If the events outlined
below were to occur
individually or in the aggregate, our business, results of operations, financial condition, and cash flows could be materially adversely affected.

19

---

Changes in government regulation or in practices relating to the pharmaceutical industry could decrease the need for the services we provide.

Governmental agencies throughout the world, but particularly in the United States, strictly regulate the drug development process. Our
business involves helping
pharmaceutical and biotechnology companies navigate the regulatory drug approval process. Changes in regulation, such as a relaxation in regulatory requirements or the introduction of simplified drug
approval procedures or an increase in regulatory requirements that we have difficulty satisfying, could eliminate or substantially reduce the need for our services. Also, if government efforts to
contain drug costs and pharmaceutical and biotechnology company profits from new drugs, our customers may spend less, or reduce their growth in spending on research and development. If health insurers
were to change their practices with respect to reimbursements for pharmaceutical products, our customers may spend less, or reduce their growth in spending on research and development.

Failure to comply with existing regulations could result in a loss of revenue or earnings or in increased costs.

Any failure on our part to comply with applicable regulations could result in the termination of on-going research or the disqualification
of data
for submission to regulatory authorities. For example, if we were to fail to verify that patient participants were fully informed and have fully consented to a particular clinical trial, the data
collected from that trial could be disqualified. If this were to happen, we could be contractually required to repeat the trial at no further cost to our customer, but at substantial cost to us.

We may bear financial losses because most of our contracts are of a fixed price nature and may be delayed or terminated or reduced in scope for reasons beyond our control.

Many
of our contracts provide for services on a fixed price or fee-for-service with a cap basis and they may be terminated or reduced in scope either immediately
or upon notice. Cancellations may occur for a variety of reasons, including:



The
loss, reduction in scope or delay of a large contract or the loss or delay of multiple contracts could materially adversely affect our business, although our contracts frequently entitle us to
receive the costs of winding down the terminated projects, as well as all fees earned by us up to the time of termination. Some contracts also entitle us to a termination fee.

We may bear financial risk if we under price our contracts or overrun cost estimates.

Since our contracts are often structured as fixed price or fee-for-service with a cap, we bear the financial risk if we initially under
price our contracts or otherwise overrun our cost estimates. Such under pricing or significant cost overruns could have a material adverse effect on our business, results of operations, financial
condition, and cash flows.

We may not be able to successfully develop and market or acquire new services.

We may seek to develop and market new services that complement or expand our existing business or expand our service offerings through
acquisition. If we are
unable to develop new services and/or create

20

---

demand
for those newly developed services, or expand our service offerings through acquisition, our future business, results of operations, financial condition, and cash flows could be adversely
affected.

Our quarterly operating results may vary.

Our operating results may vary significantly from quarter to quarter and are influenced by factors over which we have little control such
as:



We
believe that operating results for any particular quarter are not necessarily a meaningful indication of future results. While fluctuations in our quarterly operating results could
negatively or positively affect the market price of our common stock, these fluctuations may not be related to our future overall operating performance.

We depend on the pharmaceutical and biotechnology industries.

Our revenues depend greatly on the expenditures made by the pharmaceutical and biotechnology industries in research and development.
Accordingly, economic
factors and industry trends that affect our clients in these industries also affect our business. If companies in these industries were to reduce the number of research and development projects they
outsource, our business could be materially adversely affected.

We operate in a highly competitive industry.

Competitors in the contract research organization industry range from small, limited-service providers to full service global contract
research organizations.
Our main competition consists of in-house departments of pharmaceutical companies, full-service contract research organizations, and universities and teaching hospitals,
although to a lesser degree. We compete on a variety of factors, including:



For
instance, our clinical development services have from time to time experienced periods of increased price competition which had a material adverse effect on Covance's
late-stage development profitability and consolidated net revenues and net income. Covance took actions in 2000 to mitigate the effects of this price competition; however, if market
conditions were to deteriorate, additional actions might be required in the future.

There
is competition among the larger contract research organizations for both clients and potential acquisition candidates. Additionally, small, limited-service entities considering
entering the contract research organization industry will find few barriers to entry, thus further increasing possible competition. These

21

---

competitive
pressures may affect the attractiveness of our services and could adversely affect our financial results.

We may expand our business through acquisitions.

We review many acquisition candidates and, in addition to acquisitions which we have already made, we are continually evaluating new
acquisition opportunities.
Factors which may affect our ability to grow successfully through acquisitions include:



We may be affected by potential health care reform.

In recent years the United States Congress and state legislatures have considered various types of health care reform in order to control
growing health care
costs. We are unable to predict what legislative proposals will be adopted in the future, if any. Similar reform movements have occurred in Europe and Asia.

Implementation
of health care reform legislation that contain costs could limit the profits that can be made from the development of new drugs. This could adversely affect research and
development expenditures by pharmaceutical and biotechnology companies which could in turn decrease the business opportunities available to us both in the United States and abroad. In addition, new
laws or regulations may create a risk of liability, increase our costs or limit our service offerings.

We rely on third parties for important services.

We depend on third parties to provide us with services critical to our business. For instance, we have entered into an agreement with IBM
to manage our
information technology infrastructure including our computer and telephone network, e-mail system, help desks, computer support and data centers worldwide. The failure of any of these
third parties to adequately provide the needed services could have a material adverse effect on our business.

Our revenues and earnings are exposed to exchange rate fluctuations.

We derive a large portion of our net revenues from international operations. For the fiscal year ended December 31, 2003, we derived
approximately 34% of
our net revenues from outside the United States. Our financial statements are denominated in U.S. dollars. As a result, factors associated with international
operations, including changes in foreign currency exchange rates, could significantly affect our results of operations, financial condition and cash flows.

The loss of our key personnel could adversely affect our business.

Our success depends to a significant extent upon the efforts of our senior management team and other key personnel. The loss of the
services of such personnel
could adversely affect our business. Also, because of

22

---

the
nature of our business, our success is dependent upon our ability to attract and retain technologically qualified personnel. There is substantial competition for qualified personnel, and an
inability to recruit or retain qualified personnel may impact our ability to grow our business and compete effectively in our industry.

Contract research services create a risk of liability.

In
contracting to work on drug development trials, we face a range of potential liabilities, for example:



We
also contract with physicians, also referred to as investigators, to conduct the clinical trials to test new drugs on human volunteers. These tests can create a risk of liability for
personal injury or death to volunteers, resulting from negative reactions to the drugs administered or from professional malpractice by third party investigators, particularly to volunteers with
life-threatening illnesses. We believe that our risks in this area are generally reduced by the following:



Contractual
indemnifications generally do not protect us against liability arising from certain of our own actions, such as negligence or misconduct. We could be materially and
adversely affected if we were required to pay damages or bear the costs of defending any claim which is not covered by a contractual indemnification provision or in the event that a party who must
indemnify us does not fulfill its indemnification obligations or which is beyond the level of our insurance coverage. There can be no assurance that we will be able to maintain such insurance coverage
on terms acceptable to us.

Reliance on air transportation.

Our central laboratories and, to a lesser extent, our other businesses, are heavily reliant on air travel for transport of clinical trial
kits and other material
and people, and a significant disruption to the air travel system could have a material adverse effect on our business.

Actions of animal rights extremists may affect our business.

Our early development services utilize animals (predominantly rodents) in preclinical testing of the safety and efficacy of drugs and also
breed and sell animals
for biomedical research. Such activities are required for the development of new medicines and medical devices under regulatory regimes in the United States, Europe, Japan and other countries. Acts of
vandalism and other acts by animal rights extremists who object to the use of animals in drug development could have a material adverse effect on our business.

23

---

Our animal populations may suffer diseases that can damage our inventory, harm our reputation and result in decreased sales of research products.

It is important that our research products be free of diseases, including infectious diseases. The presence of diseases can distort or
compromise the quality of
research results, can cause loss of animals in our inventory or other losses. Such results could harm our reputation or have a material adverse effect on our financial condition, results of
operations, and cash flows.

Item 7a. Quantitative and Qualitative Disclosures About Market Risk

Our $150.0 million credit facility is U.S. Dollar denominated and is not subject to transaction or translation exposure. Interest on
all outstanding
borrowings under this credit facility is based upon LIBOR plus a margin. We did not have any outstanding borrowings under our credit facility during any part of the year ended December 31,
2003.

For
the year ended December 31, 2003, approximately 34% of our net revenues were derived from our operations outside the United States. We do not engage in derivative or hedging
activities related to our potential foreign exchange exposures. See "Management's Discussion and Analysis of Financial Condition and Results of OperationsForeign Currency" for a more
detailed discussion of our foreign currency risks and exposures.

24

---





Item 8.    Financial Statements and Supplementary Data

INDEX TO CONSOLIDATED FINANCIAL STATEMENTS

PageReport of Ernst & Young LLPIndependent Auditors


26Consolidated Balance SheetsDecember 31, 2003 and 2002


27Consolidated Statements of IncomeYears ended December 31, 2003, 2002 and 2001


28Consolidated Statements of Cash FlowsYears ended December 31, 2003, 2002 and 2001


29Consolidated Statements of Stockholders' EquityYears ended December 31, 2003, 2002 and 2001


30Notes to Consolidated Financial Statements


31


25

---





Report of Independent Auditors

The
Board of Directors and Stockholders
Covance Inc.

We
have audited the accompanying consolidated balance sheets of Covance Inc. and subsidiaries as of December 31, 2003 and 2002, and the related consolidated statements of
income, stockholders' equity, and cash flows for each of the three years in the period ended December 31, 2003. These financial statements are the responsibility of the Company's management.
Our responsibility is to express an opinion on these financial statements based on our audits.

We
conducted our audits in accordance with auditing standards generally accepted in the United States. Those standards require that we plan and perform the audit to obtain reasonable
assurance about whether the financial statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial
statements. An audit also includes assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe
that our audits provide a reasonable basis for our opinion.

In
our opinion, the financial statements referred to above present fairly, in all material respects, the consolidated financial position of Covance Inc. and subsidiaries at
December 31, 2003 and 2002, and the consolidated results of their operations and their cash flows for each of the three years in the period ended December 31, 2003, in conformity with
accounting principles generally accepted in the United States.

As
discussed in Note 2 to the financial statements, the Company adopted Statement of Financial Accounting Standards No. 142 in 2002.

GRAPHIC


MetroPark,
New Jersey
January 22, 2004

26

---

COVANCE INC. AND SUBSIDIARIES
CONSOLIDATED BALANCE SHEETS
DECEMBER 31, 2003 AND 2002

(Dollars in thousands)

2003

2002AssetsCurrent Assets:Cash and cash equivalents

$
171,600

$
75,913Accounts receivable


156,799


159,368Unbilled services


44,053


39,073Inventory


39,926


40,472Deferred income taxes


6,230


1,839Prepaid expenses and other current assets


31,246


28,721Total Current Assets


449,854


345,386Property and equipment, net


284,413


258,407Goodwill, net


56,876


56,805Other assets


16,482


16,405Total Assets

$
807,625

$
677,003Liabilities and Stockholders' EquityCurrent Liabilities:Accounts payable

$
20,129

$
24,123Accrued payroll and benefits


50,433


57,803Accrued expenses and other current liabilities


37,035


40,828Unearned revenue


82,227


91,681Total Current Liabilities


189,824


214,435Deferred income taxes


36,776


16,432Other liabilities


17,044


14,469Total Liabilities


243,644


245,336Commitments and Contingent LiabilitiesStockholders' Equity:Preferred stockPar value $1.00 per share; 10,000,000 shares authorized; no shares issued and outstanding at December 31, 2003 and 2002





Common stockPar value $0.01 per share; 140,000,000 shares authorized; 66,345,070 and 63,661,060 shares issued and outstanding, including those held in treasury, at
December 31, 2003 and 2002, respectively


663


637Paid-in capital


199,534


147,745Retained earnings


395,245


319,109Accumulated other comprehensive incomeCumulative translation adjustment


21,960


1,714Treasury stock at cost (3,820,531 and 3,098,322 shares at December 31, 2003 and 2002, respectively)


(53,421
)

(37,538
)Total Stockholders' Equity


563,981


431,667Total Liabilities and Stockholders' Equity

$
807,625

$
677,003


The
accompanying notes are an integral part of these consolidated financial statements.

27

---

COVANCE INC. AND SUBSIDIARIES
CONSOLIDATED STATEMENTS OF INCOME
FOR THE YEARS ENDED DECEMBER 31, 2003, 2002 AND 2001

(Dollars in thousands, except per share data)

2003

2002

2001Net revenues

$
940,300

$
883,074

$
855,877Reimbursable out-of-pockets


33,910


41,623


40,167Total revenues


974,210


924,697


896,044Costs and expenses:Cost of revenue


634,722


612,465


618,119Reimbursed out-of-pocket expenses


33,910


41,623


40,167Selling, general and administrative


143,179


133,508


127,211Depreciation and amortization


45,824


42,434


47,719Special charges








8,178Total costs and expenses


857,635


830,030


841,394Income from operations


116,575


94,667


54,650Other expense (income), net:Interest expense


1,620


2,143


8,173Interest income


(1,429
)

(1,312
)

(1,325
)Foreign exchange transaction loss, net


683


3,395


263Net gain on sale of businesses








(30,803
)Other expense (income), net


874


4,226


(23,692
)Income before taxes and equity investee earnings


115,701


90,441


78,342Taxes on income


40,021


26,658


30,442Equity investee earnings


456





Net income

$
76,136

$
63,783

$
47,900Basic earnings per share


$1.23


$1.06


$0.81Weighted average shares outstandingbasic


61,757,019


60,285,330


58,903,095Diluted earnings per share

$
1.21

$
1.03

$
0.79Weighted average shares outstandingdiluted


63,081,457


61,641,367


60,430,060


The
accompanying notes are an integral part of these consolidated financial statements.

28

---

COVANCE INC. AND SUBSIDIARIES
CONSOLIDATED STATEMENTS OF CASH FLOWS
FOR THE YEARS ENDED DECEMBER 31, 2003, 2002 AND 2001

(Dollars in thousands)

2003

2002

2001Cash flows from operating activities:Net income

$
76,136

$
63,783

$
47,900Adjustments to reconcile net income to net cash provided by operating activities:Depreciation and amortization


45,824


42,434


47,719Stock issued under employee benefit and stock compensation plans


12,992


11,672


12,509Deferred income tax provision


15,953


16,656


1,164Net gain on sale of businesses








(30,803
)Restructuring charge, net of cash paid








7,287Other


923


2,036


1,399Changes in operating assets and liabilities, net of businesses acquired and sold:Accounts receivable


2,569


9,054


(25,798
)Unbilled services


(4,980
)

1,822


746Inventory


546


(4,341
)

(8,542
)Accounts payable


(3,994
)

2,867


(4,020
)Accrued liabilities


(10,523
)

11,689


(9,555
)Unearned revenue


(9,454
)

(25,175
)

25,627Income taxes payable





(2,739
)

2,334Other assets and liabilities, net


14,173


(5,876
)

(964
)Net cash provided by operating activities


140,165


123,882


67,003Cash flows from investing activities:Capital expenditures


(62,639
)

(66,784
)

(78,136
)Acquisition of business, net of cash acquired





(2,796
)

Proceeds from sale of businesses








251,059Other, net


39


11


73Net cash (used in) provided by investing activities


(62,600
)

(69,569
)

172,996Cash flows from financing activities:Stock issued under employee stock purchase and option plans


27,685


13,874


17,157Purchase of treasury stock


(15,883
)

(16,631
)

(1,000
)Net repayments under revolving credit facility





(15,000
)

(209,000
)Repayments of debt








(18,723
)Net cash provided by (used in) financing activities


11,802


(17,757
)

(211,566
)Effect of exchange rate changes on cash


6,320


3,953


(220
)Net change in cash and cash equivalents


95,687


40,509


28,213Cash and cash equivalents, beginning of year


75,913


35,404


7,191Cash and cash equivalents, end of year

$
171,600

$
75,913

$
35,404


The
accompanying notes are an integral part of these consolidated financial statements.

29

---

COVANCE INC. AND SUBSIDIARIES
CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY
FOR THE YEARS ENDED DECEMBER 31, 2003, 2002 AND 2001

(Dollars in thousands)

Common
Stock

Paid-in
Capital

Retained
Earnings

Accumulated
Other
Comprehensive
Income (Loss)

Comprehensive
Income

Treasury
Stock

Total
Stockholders'
EquityBalance, December 31, 2000

$
598

$
92,572

$
207,426

$
(14,938
)



$
(19,907
)
$
265,751Comprehensive income:Net income








47,900




$
47,900





47,900Currency translation adjustment











2,628


2,628





2,628Total comprehensive income













$
50,528





Shares issued under various employee benefit and stock compensation plans


11


15,643














15,654Stock option exercises


10


14,002














14,012Treasury stock, at cost

















(1,000
)

(1,000
)Balance, December 31, 2001


619


122,217


255,326


(12,310
)




(20,907
)

344,945Comprehensive income:Net income








63,783




$
63,783





63,783Currency translation adjustment











14,024


14,024





14,024Total comprehensive income













$
77,807





Shares issued under various employee benefit and stock compensation plans


9


14,349














14,358Stock option exercises


9


11,179














11,188Treasury stock, at cost

















(16,631
)

(16,631
)Balance, December 31, 2002


637


147,745


319,109


1,714





(37,538
)

431,667Comprehensive income:Net income








76,136




$
76,136





76,136Currency translation adjustment











20,246


20,246





20,246Total comprehensive income













$
96,382





Shares issued under various employee benefit and stock compensation plans


7


15,596














15,603Stock option exercises


19


25,055














25,074Tax effect of stock options exercised





11,138














11,138Treasury stock, at cost

















(15,883
)

(15,883
)Balance, December 31, 2003

$
663

$
199,534

$
395,245

$
21,960




$
(53,421
)
$
563,981


The accompanying notes are an integral part of these consolidated financial statements.

30

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

1. Organization

Covance Inc. and its subsidiaries ("Covance") is a leading drug development services company providing a wide range of early stage
and late stage product
development services on a worldwide basis primarily to the pharmaceutical, biotechnology and medical device industries. Covance also provides services such as laboratory testing to the chemical,
agrochemical and food industries. Covance's operations constitute two segments for financial reporting purposes. The first segment, early development services, includes preclinical and Phase I
clinical service offerings. The second segment, late-stage development services, includes central laboratory, clinical development, periapproval, central ECG diagnostic services, and
healthcare economic and reimbursement services. Operations are principally focused in the United States and Europe.

2. Summary of Significant Accounting Policies



The consolidated financial statements include the accounts of all entities controlled by Covance, including through June 15, 2001,
Covance Biotechnology
Services Inc. ("Biomanufacturing"), a majority owned business. All significant intercompany accounts and transactions are eliminated. The equity method of accounting is used for investments in
affiliates in which Covance owns between 20 and 50 percent and does not have the ability to exercise significant influence. See Note 4.



These consolidated financial statements have been prepared in conformity with accounting principles generally accepted in the United
States, which require
management to make estimates and assumptions about future events that affect the amounts reported in the financial statements and the accompanying notes. Actual results could differ from these
estimates.



Certain prior period balances have been reclassified to conform with current year presentation.



For subsidiaries outside of the United States that operate in a local currency environment, income and expense items are translated to
United States dollars at
the monthly average rates of exchange prevailing during the year, assets and liabilities are translated at year-end exchange rates and equity accounts are translated at historical exchange
rates. Translation adjustments are accumulated in a separate component of stockholders' equity in the Consolidated Balance Sheets and are included in the determination of comprehensive income in the
Consolidated Statements of Stockholders' Equity. Transaction gains and losses are included in the determination of net income in the Consolidated Statements of Income.



Cash and cash equivalents include all highly liquid investments with an original maturity of three months or less at date of purchase and
consist principally of
amounts invested in money market funds.

31

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

2. Summary of Significant Accounting Policies (Continued)



The fair value of cash and cash equivalents, accounts receivable, accounts payable, accrued expenses and long and short-term debt
approximate their
carrying amounts as reported at December 31, 2003 and 2002.

Accounts
receivable and unbilled services represent amounts due from Covance customers who are concentrated primarily in the pharmaceutical and biotechnology industries. Covance
endeavors to monitor the creditworthiness of its customers to which it grants credit terms in the ordinary course of business. Although Covance customers are concentrated primarily within these two
industries, management considers the likelihood of material credit risk as remote. In addition, in some cases Covance requires advance payment for a portion of the contract price from its customers
upon the signing of a contract for services. These amounts are deferred and recognized as revenue as services are performed. Historically, bad debts have been immaterial.



Inventories, which consist principally of finished goods and supplies, are valued at the lower of cost (first-in, first-out method) or
market.



In connection with the management of multi-site clinical trials, Covance pays on behalf of its customers fees to investigators, volunteers
and other
out-of-pocket costs (such as travel, printing, meetings, couriers, etc.), for which we are reimbursed at cost, without mark-up or profit. Amounts receivable from
customers in connection with billed and unbilled investigator fees, volunteer payments and other out-of-pocket pass-through costs are included in prepaid expenses
and other current assets in the accompanying Consolidated Balance Sheets and totaled $14.5 million and $13.3 million at December 31, 2003 and 2002, respectively. See Note 2
"Reimbursable Out-of-Pocket Expenses".



Property and equipment are recorded at cost. Depreciation and amortization are provided on the straight-line method at rates adequate to
allocate the
cost of the applicable assets over their estimated useful lives, which range in term from three to thirty years. The cost of computer software developed or obtained for internal use is accounted for
in accordance with the Accounting Standards Executive Committee's Statement of Position 98-1,Accounting for the Costs of Computer Software Developed or Obtained
for Internal Use.Repairs and maintenance are expensed as incurred.



Effective January 1, 2002, in accordance with the adoption of Statement of Financial Accounting Standards ("SFAS") No. 142, Goodwill and Other Intangible Assets,Covance ceased amortization of goodwill. Prior to January 1, 2002, goodwill (investment costs in excess of
the fair value of net tangible and identifiable intangible assets acquired) was capitalized and amortized on a straight-line basis over the period expected to be benefited, which was
generally twenty years or less, except for acquisitions prior to 1996 which were being amortized over forty years. Had amortization expense not been recorded for the year ended December 31,
2001, the impact on income from operations, net income and earnings per share would have been an increase of

32

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

2. Summary of Significant Accounting Policies (Continued)

$3.6 million,
$2.9 million and $0.05 per share, respectively. SFAS No. 142 also outlines the requirements for annual goodwill impairment tests, and accordingly, Covance performs
an annual test for impairment of goodwill. The annual test for impairment performed for 2003 did not identify any instances of impairment.



Effective January 1, 2002, Covance assesses impairment of long-lived assets in accordance with SFAS No. 144, Accounting for the Impairment or Disposal of Long-Lived Assets. Assessments of the recoverability of long-lived assets are
conducted when events or changes in circumstances occur that indicate that the carrying value of the asset may not be recoverable. The assessment of possible impairment is based upon the ability to
recover the asset from the expected future undiscounted cash flows of related operations. No events have been identified that caused an evaluation of the recoverability of the long-lived
assets for the years ended December 31, 2003, 2002 and 2001.



Covance recognizes revenue either as services are performed or products are delivered, depending upon the nature of the work contracted.
Historically, a majority
of Covance's net revenues have been earned under contracts which range in duration from a few months to two years, but can extend in duration up to five years or longer. Service contracts generally
take the form of fee-for-service or fixed-price arrangements. In the case of fee-for-service contracts, revenue is recognized as services are performed,
based upon, for example, hours worked or samples tested. For long-term fixed-price service contracts, revenue is recognized as services are performed, with performance generally assessed
using output measures, such as units-of-work performed to date as compared to the total units-of-work contracted. Changes
in the scope of work generally result in a renegotiation of contract pricing terms. Renegotiated amounts are not included in net revenues until earned and realization is assured. Estimates of costs to
complete are made to provide, where appropriate, for losses expected on contracts. Costs are not deferred in anticipation of contracts being awarded, but instead are expensed as incurred. In some
cases, for multi-year contracts a portion of the contract fee is paid at the time the trial is initiated. These advances are deferred and recognized as revenue as services are performed,
as discussed above. Additional payments may be made based upon the achievement of performance-based milestones over the contract duration. Most contracts are terminable by the client either
immediately or upon notice. These contracts typically require payment to Covance of expenses to wind down the study, fees earned to date and, in some cases, a termination fee or a payment to Covance
of some portion of the fees or profits that could have been earned by Covance under the contract if it had not been terminated early. Termination fees are included in net revenues when realization is
assured. In connection with the management of multi-site clinical trials, Covance pays on behalf of its customers fees to investigators, volunteers and other
out-of-pocket costs (such as for travel, printing, meetings, couriers, etc.), for which it is reimbursed at cost, without mark-up or profit. Investigator fees are
not reflected in total revenues or expenses where Covance acts in the capacity of an agent on behalf of the pharmaceutical company sponsor, passing through these costs without risk or reward to
Covance. All other out-of-pocket costs are included in total revenues and expenses.

Unbilled
services are recorded for revenue recognized to date and relate to amounts that are currently unbillable to the customer pursuant to contractual terms. In general, amounts
become billable upon the achievement of milestones or in accordance with predetermined payment schedules. Unbilled services are billable to customers within one year from the respective balance sheet
date. Unearned revenue is recorded for cash received from customers for which revenue has not been recognized at the balance sheet date.

33

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

2. Summary of Significant Accounting Policies (Continued)



Cost of revenue includes direct labor and related benefit charges, other direct costs, shipping and handling fees, and an allocation of
facility charges and
information technology costs and excludes depreciation and amortization. Selling, general and administrative expenses primarily consist of administrative payroll and related benefit charges,
advertising and promotional expenses, administrative travel and an allocation of facility charges and information technology costs and excludes depreciation and amortization. Advertising expense is
recognized as incurred.



Covance uses the asset and liability method of accounting for income taxes. Under this method, deferred tax assets and liabilities are
recognized for the
expected future tax consequences of differences between the carrying amounts of assets and liabilities and their respective tax bases using enacted tax rates in effect for the year in which the
temporary differences are expected to reverse. The effect on deferred taxes of a change in enacted tax rates is recognized in income in the period when the change is effective. See Note 7.

Covance
has established, and periodically reviews and reevaluates, an estimated income tax reserve on its consolidated balance sheet to provide for the possibility of adverse outcomes
in tax proceedings. When matters are settled or when facts indicate a material change in the probability or amount of the potential exposure, Covance adjusts the carrying value of the related reserve.
As a result of favorable income tax developments, relating primarily to the settlement of a longstanding multi-year foreign income tax audit, Covance reduced its income tax reserve and
provision by $6.5 million during 2002.



Covance's total comprehensive income represents net income plus the change in the cumulative translation adjustment equity account for the
periods presented.



Covance has several stock-based compensation plans as described in Note 10. Effective January 1, 2003, Covance adopted SFAS
No. 148, Accounting for Stock-Based CompensationTransition and Disclosure.SFAS No. 148 amends SFAS No. 123, Accounting for Stock-Based
Compensation, to provide, among other things, prominent disclosure of the effects of the entity's accounting policy with
respect to stock-based employee compensation on reported net income and earnings per share in annual and interim financial statements. Covance intends to continue to follow the
disclosure-only provisions of SFAS No. 123 and, accordingly, will continue to account for these plans under the recognition and measurement principles of APB Opinion No. 25, Accounting for Stock Issued to
Employees, and related interpretations. Under APB 25, when stock options are issued with an exercise price equal to the
market price of the underlying stock price on the date of grant, no compensation expense is recognized.

The
fair value of the Covance stock options used to compute the net income and earnings per share disclosures required under SFAS No. 123 is the estimated present value at grant
date using the Black-Scholes option-pricing model with the following weighted average assumptions for 2003, 2002 and 2001, respectively: expected volatility of 44.9%, 47.1% and 47.7%; risk free
interest rate of 3.42%, 4.71% and 4.74%; and an expected holding period of seven years.

34

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

2. Summary of Significant Accounting Policies (Continued)

While
Covance does record compensation expense related to awards of stock, no compensation cost is recorded for option grants under Covance's stock option plans as all options granted
under these plans are issued with an exercise price equal to the market value of the underlying common stock on the date of grant. The following table illustrates the effect on net income and earnings
per share for the years ended December 31, 2003, 2002 and 2001 had Covance applied the fair value recognition provisions of SFAS No. 123,Accounting for
Stock-Based Compensation, to all of its stock-based employee compensation plans.

2003

2002

2001Net income, as reported

$
76,136

$
63,783

$
47,900Add: Stock award-based employee compensation included in reported net income,
net of related tax effects


2,743


1,939


906Deduct: Total stock-based employee compensation expense determined under fair
value based method for all awards, net of related tax effects


(12,323
)

(9,294
)

(6,655
)Pro forma net income

$
66,556

$
56,428

$
42,151Earnings per share:Basicas reported


$1.23


$1.06


$0.81Basicpro forma


$1.08


$0.94


$0.72Dilutedas reported


$1.21


$1.03


$0.79Dilutedpro forma


$1.06


$0.92


$0.70




Basic EPS is computed by dividing net income available to common stockholders by the weighted average number of shares outstanding during
the period. The
computation of diluted EPS is similar to the computation of basic EPS, except that the denominator is increased to include the number of additional common shares that would have been outstanding if
the dilutive potential common shares had been issued; computed under the treasury stock method in accordance with the requirements of SFAS No. 128,Earnings Per
Share.

In
computing diluted EPS for the years ended December 31, 2003, 2002 and 2001, the denominator was increased by 1,324,438 shares, 1,356,037 shares and 1,526,965 shares,
respectively, representing the dilutive effect of stock options outstanding at December 31, 2003, 2002 and 2001, with exercise prices less than the average market price of Covance's common
stock during each respective period. Excluded from the computation of diluted EPS for the year ended December 31, 2003 were options to purchase 804,416 shares of common stock at prices ranging
from $26.94 to $29.13 per share because the exercise prices of such options were greater than the average market price of Covance's common stock during 2003. Excluded from the computation of diluted
EPS for the year ended December 31, 2002 were options to purchase 3,035,281 shares of common stock at prices ranging from $18.98 to $29.13 per share because the exercise prices of such options
were greater than the average market price of Covance's common stock during 2002. Excluded from the computation of diluted EPS for the year ended December 31, 2001 were options to purchase
3,242,366 shares of common stock at prices ranging from $17.78 to $29.13 per share because the exercise prices of such options were greater than the average market price of Covance's common stock
during 2001.

35

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

2. Summary of Significant Accounting Policies (Continued)



As discussed in Note 2 "Prepaid Expenses and Other Current Assets", Covance pays on behalf of its customers fees to investigators,
volunteers and other
out-of-pocket costs for
which we are reimbursed at cost, without mark-up or profit. Effective January 1, 2002, in connection with the required implementation of Financial Accounting Standards Board
Emerging Issues Task Force Rule No. 01-14 ("EITF 01-14"),Income Statement Characterization of Reimbursements Received for
"Out-of-Pocket" Expenses Incurred, amounts paid to volunteers and other out-of- pocket costs are reflected in operating
expenses, while the reimbursements received are reflected in revenues in the Consolidated Statements of Income. Covance will continue to exclude from revenue and expense in the Consolidated Statements
of Income fees paid to investigators and the associated reimbursement since Covance acts as an agent on behalf of the pharmaceutical company sponsors with regard to investigator payments.



Cash paid for interest for the years ended December 31, 2003, 2002 and 2001 totaled $0.9 million, $1.2 million and
$9.0 million,
respectively. Cash paid for income taxes for the years ended December 31, 2003, 2002 and 2001 totaled $16.6 million, $24.0 million and $24.0 million, respectively.

3. Property and Equipment

Property and equipment at December 31, 2003 and 2002 consist of the following:

2003

2002Property and equipment at cost:Land

$
26,465

$
24,390Buildings and improvements


215,890


175,153Equipment and vehicles


161,686


144,734Computer hardware and software


150,662


136,590Furniture, fixtures & leasehold improvements


72,933


66,458Construction-in-progress


6,202


12,046633,838


559,371Less: Accumulated depreciation and amortization


(349,425
)

(300,964
)Property and equipment, net

$
284,413

$
258,407


Depreciation
and amortization expense aggregated $45.8 million, $42.4 million and $44.0 million for 2003, 2002 and 2001, respectively.

4. Investment in Affiliate

Covance has a minority equity position (approximately 22% at December 31, 2003) in Bio-Imaging Technologies, Inc. ("BITI"). BITI
uses
proprietary medical imaging technologies to process and analyze medical images, and also provides other services, including the data-basing and regulatory submission of medical images,
quantitative data and text. During the year ended December 31, 2003, Covance recognized

36

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

4. Investment in Affiliate (Continued)

income
of $0.5 million, representing its pro rata share of BITI's earnings. The carrying value of Covance's investment in BITI as of December 31, 2003 was $0.5 million while the
fair market value was $14.7 million.

5. Goodwill

Effective January 1, 2002, in accordance with the adoption of SFAS No. 142,Goodwill and Other Intangible
Assets, Covance ceased amortization of goodwill. Goodwill, net of accumulated amortization of $17.7 million, aggregated $56.9 million and $56.8 million at
December 31, 2003 and 2002, respectively. Amortization expense aggregated $3.7 million for 2001. Early development segment goodwill, net of accumulated amortization totaled
$6.7 million at both December 31, 2003 and 2002. Late-stage development segment goodwill, net of accumulated amortization totaled $50.2 million and
$50.1 million at December 31, 2003 and 2002, respectively.

6. Acquisitions and Divestitures

In July 2002, Covance acquired the stock of Virtual Central Laboratory b.v. (now known as Covance Virtual Central Laboratory b.v.)
for a cash payment of
$3.0 million. The goodwill resulting from this transaction aggregated $2.7 million.

On
June 15, 2001, Covance sold its biomanufacturing business ("Biomanufacturing") to Akzo Nobel's pharma business unit, Diosynth, for gross proceeds of $113.6 million.
Covance recognized a pre-tax loss of $7.5 million ($4.5 million after tax) from this transaction. Covance used the net proceeds from the sale of approximately
$95 million to reduce borrowings under its senior revolving credit facility.

On
February 14, 2001, Covance sold its pharmaceutical packaging business ("Packaging") to Fisher Scientific International Inc. for gross proceeds of $137.5 million.
Covance recognized a pre-tax gain of $38.4 million ($24.3 million after tax) from this transaction. Covance used the net proceeds from the sale to repay the
$18.5 million balance outstanding on the mortgage on its North American packaging facility and the remaining net proceeds of approximately $95 million were used to reduce borrowings
under its senior revolving credit facility.

37

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

7. Taxes on Income

The components of income before taxes and the related provision (benefit) for taxes on income for 2003, 2002 and 2001 are as follows:

2003

2002

2001Income before taxes and equity investee results:Domestic

$
63,838

$
53,564

$
17,090International


51,863


36,877


61,252Total

$
115,701

$
90,441

$
78,342Federal income taxes:Current provision

$
11,914

$
6,251

$
8,839Deferred provision


10,228


6,162


1,549International income taxes:Current provision


11,288


8,501


15,835Deferred provision


2,279


1,229


409State and other income taxes:Current provision


2,851


3,635


3,589Deferred provision


1,461


880


221Net income tax provision

$
40,021

$
26,658

$
30,442


The
differences between the provision for income taxes and income taxes computed using the Federal statutory income tax rate for 2003, 2002 and 2001 are as follows:

2003

2002

2001Taxes at statutory rate


35.0
%

35.0
%

35.0
%State and local taxes, net of Federal benefit


2.4


3.2


3.2Goodwill amortization








1.0Impact of international operations


(3.9
)

(3.5
)

(2.4
)Reduction of income tax reserve





(7.2
)

Other, net


1.1


2.0


2.1Total


34.6
%

29.5
%

38.9
%


38

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

7. Taxes on Income (Continued)

The
tax effects of temporary differences that give rise to significant portions of the deferred tax assets and liabilities at December 31, 2003 and 2002 are as follows:

2003

2002Current deferred tax assets:Liabilities not currently deductible

$
5,775

$
727Net operating loss carryforwards





657Other


455


455Current deferred tax assets

$
6,230

$
1,839Noncurrent deferred tax assets:Liabilities not currently deductible

$
2,124

$
4,265Less: Valuation allowance





(1,212
)Net noncurrent deferred tax assets


2,124


3,053Noncurrent deferred tax liabilities:Property and equipment


(38,900
)

(19,485
)Net noncurrent deferred tax liabilities

$
(36,776
)
$
(16,432
)


The
$19.4 million increase in the non-current deferred tax liability is due to accelerated depreciation deductions for income tax purposes on assets acquired in the
United States and the United Kingdom.

During
the third quarter of 2002, Covance recognized a tax benefit of $6.5 million resulting from favorable income tax developments, relating primarily to the settlement of a
longstanding foreign income tax audit.

Covance
currently provides income taxes on the earnings of foreign subsidiaries to the extent those earnings are taxable or are expected to be remitted. Taxes have not been provided on
the remaining $127.0 million of accumulated foreign unremitted earnings because those earnings are expected to remain invested indefinitely. It is not practical to estimate the amount of
additional tax that might be payable if such accumulated earnings were remitted. Additionally, if such accumulated earnings were remitted, certain countries impose withholding taxes that, subject to
certain limitations, are available for use as a tax credit against any Federal income tax liability arising from such remittance.

8. Long-Term Debt

On June 28, 2001, Covance replaced its credit facility with a new $150.0 million senior revolving credit facility (the "Credit
Facility") which
expires in June 2004. During the year ended December 31, 2003 and at both December 31, 2003 and 2002, there were no outstanding borrowings under the Credit Facility. At
December 31, 2003 and 2002, there were $2.2 million and $1.6 million, respectively, of outstanding letters of credit, under the Credit Facility. At December 31, 2003,
Covance has a remaining availability under the Credit Facility of $147.8 million of which $22.8 million remains available for letters of credit. Interest on all outstanding borrowings
under Covance's Credit Facility is based upon the London Interbank Offered Rate ("LIBOR") plus a margin and approximated 3.28% and 7.21% per annum for the years ended December 31, 2002 and
2001, respectively. Costs associated with replacing the senior revolving credit facility, consisting primarily of bank fees totaling $1.7 million, are being amortized over the three year term
of the Credit Facility.

39

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

8. Long-Term Debt (Continued)

The
Credit Facility contains various covenants, which among other things, restrict certain uses of cash such as certain restrictions on Covance's ability to pay cash dividends on the
Covance common stock. At December 31, 2003, Covance was in compliance with the terms of its Credit Facility. Commitment fees paid during 2003, 2002 and 2001, which under the prior senior
revolving credit facility were 0.5 percent of the revolving committed amount, and under the new Credit Facility were 0.5 percent of the undrawn balance of the Credit Facility,
approximated $0.8 million, $0.7 million, and $1.0 million, respectively. The Credit Facility is collateralized by guarantees of certain of Covance's domestic subsidiaries and a
pledge of 65 percent of the capital stock of certain of Covance's foreign subsidiaries.

9. Employee Benefit Plans

Covance sponsors various pension and other post-retirement benefit plans.



Covance sponsors two defined benefit pension plans for the benefit of its employees at two United Kingdom subsidiaries and one defined
benefit pension plan for
the benefit of its employees at a German subsidiary, all of which are legacy plans of previously acquired companies. Benefit amounts for all three plans are based upon years of service and
compensation. The German plan is unfunded while the UK plans are funded. Covance's funding policy has been to contribute annually a fixed percentage of the eligible employee's salary at least equal to
the local statutory funding requirements. Pension plan assets are administered by the plans' trustees and are principally invested in equity and fixed income securities. The components of net periodic
pension expense for these plans for 2003, 2002 and 2001 are as follows:

|                                                         |  |   |        |   |   |        |   |   |        |   |   |      |   |   |      |   |   |      |  
|-------------------------------------------------------- |  | - | ------ | - | - | ------ | - | - | ------ | - | - | ---- | - | - | ---- | - | - | ---- | -
|
|
|Components of Net Periodic Pension Cost:                 |  |   |        |   |   |        |   |   |        |   |   |      |   |   |      |   |   |      |  
|Service cost                                             |  | $ | 4,198  |   | $ | 3,844  |   | $ | 3,924  |   | $ | 251  |   | $ | 238  |   | $ | 173  |  
|Interest cost                                            |  |   | 3,773  |   |   | 2,905  |   |   | 2,562  |   |   | 207  |   |   | 159  |   |   | 119  |  
|Expected return on plan assets                           |  |   | (3,222 | ) |   | (2,518 | ) |   | (2,484 | ) |   |     |   |   |     |   |   |     |  
|Amortization of net actuarial loss                       |  |   | 1,185  |   |   | 142    |   |   | (58    | ) |   | 6    |   |   | 5    |   |   | 4    |  
|Participant contributions                                |  |   | (1,852 | ) |   | (1,392 | ) |   | (1,289 | ) |   |     |   |   |     |   |   |     |  
|                                                         |  |   |        |   |   |        |   |   |        |   |   |      |   |   |      |   |   |      |  
|Net periodic pension cost                                |  | $ | 4,082  |   | $ | 2,981  |   | $ | 2,655  |   | $ | 464  |   | $ | 402  |   | $ | 296  |  
|                                                         |  |   |        |   |   |        |   |   |        |   |   |      |   |   |      |   |   |      |  
|Assumptions Used to Determine Net Periodic Pension Cost: |  |   |        |   |   |        |   |   |        |   |   |      |   |   |      |   |   |      |  
|Discount rate                                            |  |   | 6.00   | % |   | 6.50   | % |   | 6.25   | % |   | 5.75 | % |   | 6.00 | % |   | 6.00 | %
|Expected rate of return on assets                        |  |   | 6.00   | % |   | 6.50   | % |   | 6.25   | % |   | n/a  |   |   | n/a  |   |   | n/a  |  
|Salary increases                                         |  |   | 3.50   | % |   | 3.50   | % |   | 3.50   | % |   | 3.00 | % |   | 3.25 | % |   | 3.50 | %
|                                                         |  |   |        |   |   |        |   |   |        |   |   |      |   |   |      |   |   |      |  

40

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

9. Employee Benefit Plans (Continued)

The
change in the projected benefit obligation and plan assets and a reconciliation of the funded status of the plans to the amounts reported in the consolidated balance sheets as of
December 31, 2003 and 2002 is as follows:

|                                                                        |  |   |         |   |   |         |   |   |        |   |   |        |  
|----------------------------------------------------------------------- |  | - | ------- | - | - | ------- | - | - | ------ | - | - | ------ | -
|
|
|Change in Projected Benefit Obligation:                                 |  |   |         |   |   |         |   |   |        |   |   |        |  
|Benefit obligation beginning of year                                    |  | $ | 61,856  |   | $ | 44,439  |   | $ | 3,050  |   | $ | 2,215  |  
|Service cost                                                            |  |   | 4,198   |   |   | 3,844   |   |   | 251    |   |   | 238    |  
|Interest cost                                                           |  |   | 3,773   |   |   | 2,905   |   |   | 207    |   |   | 159    |  
|Actuarial loss (gain)                                                   |  |   | 3,192   |   |   | 5,533   |   |   | (99    | ) |   | 155    |  
|Benefits paid                                                           |  |   | (1,177  | ) |   | (472    | ) |   | (72    | ) |   | (43    | )
|Foreign currency exchange rate changes                                  |  |   | 7,578   |   |   | 5,607   |   |   | 607    |   |   | 326    |  
|                                                                        |  |   |         |   |   |         |   |   |        |   |   |        |  
|Benefit obligation end of year                                          |  | $ | 79,420  |   | $ | 61,856  |   | $ | 3,944  |   | $ | 3,050  |  
|                                                                        |  |   |         |   |   |         |   |   |        |   |   |        |  
|Change in Fair Value of Assets:                                         |  |   |         |   |   |         |   |   |        |   |   |        |  
|Fair value of plan assets beginning of year                             |  | $ | 50,530  |   | $ | 36,622  |   | $ |       |   | $ |       |  
|Covance contributions                                                   |  |   | 3,008   |   |   | 15,632  |   |   |       |   |   |       |  
|Employee contributions                                                  |  |   | 1,749   |   |   | 1,392   |   |   |       |   |   |       |  
|Actual return on plan assets                                            |  |   | 7,872   |   |   | (7,229  | ) |   |       |   |   |       |  
|Benefits paid                                                           |  |   | (1,177  | ) |   | (472    | ) |   |       |   |   |       |  
|Foreign currency exchange rate changes                                  |  |   | 6,472   |   |   | 4,585   |   |   |       |   |   |       |  
|                                                                        |  |   |         |   |   |         |   |   |        |   |   |        |  
|Fair value of plan assets end of year                                   |  | $ | 68,454  |   | $ | 50,530  |   | $ |       |   | $ |       |  
|                                                                        |  |   |         |   |   |         |   |   |        |   |   |        |  
|Reconciliation of Funded Status of the Plans to Balance Sheet Position: |  |   |         |   |   |         |   |   |        |   |   |        |  
|Funded statusover (under) funded                                       |  | $ | (10,966 | ) | $ | (11,326 | ) | $ | (3,944 | ) | $ | (3,050 | )
|Unrecognized net actuarial loss                                         |  |   | 24,453  |   |   | 24,541  |   |   |       |   |   | 298    |  
|                                                                        |  |   |         |   |   |         |   |   |        |   |   |        |  
|Balance sheet positionprepaid (accrued)                                |  | $ | 13,487  |   | $ | 13,215  |   | $ | (3,944 | ) | $ | (2,752 | )
|                                                                        |  |   |         |   |   |         |   |   |        |   |   |        |  
|Assumptions Used to Determine Benefit Obligations:                      |  |   |         |   |   |         |   |   |        |   |   |        |  
|Discount rate                                                           |  |   | 6.00    | % |   | 6.00    | % |   | 5.75   | % |   | 5.75   | %
|Salary increases                                                        |  |   | 3.50    | % |   | 3.50    | % |   | 3.00   | % |   | 3.00   | %
|                                                                        |  |   |         |   |   |         |   |   |        |   |   |        |  

41

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

9. Employee Benefit Plans (Continued)



In addition to these foreign defined benefit pension plans, Covance also has a non-qualified Supplemental Executive Retirement Plan
("SERP"). The
SERP, which is not funded, is intended to provide retirement benefits for certain executive officers of Covance. Benefit amounts are based upon years of service and compensation of the participating
employees. The measurement date for the SERP is November 30. The components of net periodic pension cost for the years ended December 31, 2003, 2002 and 2001 are as follows:

|                                                         |  |   |      |   |   |      |   |   |      |  
|-------------------------------------------------------- |  | - | ---- | - | - | ---- | - | - | ---- | -
|
|Components of Net Periodic Pension Cost:                 |  |   |      |   |   |      |   |   |      |  
|Service cost                                             |  | $ | 563  |   | $ | 442  |   | $ | 424  |  
|Interest cost                                            |  |   | 391  |   |   | 300  |   |   | 170  |  
|Amortization of net actuarial loss                       |  |   | 8    |   |   |     |   |   |     |  
|                                                         |  |   |      |   |   |      |   |   |      |  
|Net periodic pension cost                                |  | $ | 962  |   | $ | 742  |   | $ | 594  |  
|                                                         |  |   |      |   |   |      |   |   |      |  
|Assumptions Used to Determine Net Periodic Pension Cost: |  |   |      |   |   |      |   |   |      |  
|Discount rate                                            |  |   | 6.75 | % |   | 7.25 | % |   | 7.50 | %
|Salary increases                                         |  |   | 4.50 | % |   | 4.75 | % |   | 4.75 | %
|                                                         |  |   |      |   |   |      |   |   |      |  

The
change in the projected benefit obligation and the reconciliation of such amount to that reported in the consolidated balance sheets as of December 31, 2003 and 2002 is as
follows:

|                                                                       |  |   |        |   |   |        |  
|---------------------------------------------------------------------- |  | - | ------ | - | - | ------ | -
|
|Change in Projected Benefit Obligation:                                |  |   |        |   |   |        |  
|Benefit obligation beginning of year                                   |  | $ | 5,230  |   | $ | 3,690  |  
|Service cost                                                           |  |   | 563    |   |   | 442    |  
|Interest cost                                                          |  |   | 391    |   |   | 300    |  
|Actuarial loss                                                         |  |   | 490    |   |   | 798    |  
|Plan Amendments                                                        |  |   | 763    |   |   |       |  
|                                                                       |  |   |        |   |   |        |  
|Benefit obligation end of year                                         |  | $ | 7,437  |   | $ | 5,230  |  
|                                                                       |  |   |        |   |   |        |  
|Reconciliation of Funded Status of the Plan to Balance Sheet Position: |  |   |        |   |   |        |  
|Funded statusover (under) funded                                      |  | $ | (7,437 | ) | $ | (5,230 | )
|Unrecognized actuarial net loss (gain)                                 |  |   | 1,077  |   |   | 595    |  
|Unrecognized prior service cost                                        |  |   | 763    |   |   |       |  
|                                                                       |  |   |        |   |   |        |  
|Accrued benefit liability                                              |  | $ | (5,597 | ) | $ | (4,635 | )
|                                                                       |  |   |        |   |   |        |  
|Assumptions Used to Determine Benefit Obligation:                      |  |   |        |   |   |        |  
|Discount rate                                                          |  |   | 6.25   | % |   | 6.75   | %
|Salary increases                                                       |  |   | 4.00   | % |   | 4.50   | %
|                                                                       |  |   |        |   |   |        |  

The
accumulated benefit obligation as of December 31, 2003 and 2002 is $5,813 and $4,051, respectively.

42

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

9. Employee Benefit Plans (Continued)



Covance also sponsors a post-employment retiree health and welfare plan for the benefit of eligible employees at certain U.S. subsidiaries
who retire
after satisfying service and age requirements. This
plan is funded on a pay-as-you-go basis and the cost of providing these benefits is shared with the retirees. The measurement date for this plan is
November 30. The components of net periodic post-retirement benefits expense for 2003, 2002 and 2001 are as follows:

2003

2002

2001Components of Net Periodic Post-retirement Benefits Cost:Service cost

$
222

$
190

$
175Interest cost


383


328


319Amortization of prior service cost (benefit)


(397
)

(397
)

(397
)Amortization of net actuarial loss


182


79


77Net periodic post-retirement benefits cost

$
390

$
200

$
174Assumptions Used:Discount rate


6.75
%

7.25
%

7.50
%Health care cost trend rate


9.90
%(a)

9.50
%(a)

10.00
%(a)


---

The
change in the projected post-retirement benefit obligation and the reconciliation of such amount to that reported in the consolidated balance sheets as of
December 31, 2003 and 2002 is as follows:

2003

2002Change in Projected Benefit Obligation:Benefit obligation beginning of year

$
4,987

$
4,520Service cost


222


190Interest cost


383


328Participant contributions


118


89Actuarial loss


954


360Benefits paid


(495
)

(500
)Benefit obligation end of year

$
6,169

$
4,987Reconciliation of Funded Status of the Plan to Balance Sheet Position:Funded statusover (under) funded

$
(6,169
)
$
(4,987
)Unrecognized actuarial net loss


2,143


1,371Unrecognized prior service cost


(390
)

(787
)Accrued benefit liability

$
(4,416
)
$
(4,403
)Assumptions Used to Determine Benefit Obligation:Discount rate


6.25
%

6.75
%Health care cost trend rate


10.00
%(a)

9.90
%(a)


---

43

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

9. Employee Benefit Plans (Continued)

A
one-percentage-point increase in the assumed health care cost trend rate would increase the net service and interest cost components of the net periodic
post-retirement benefits expense by $5 and would increase the post-retirement benefit obligation by $45. A one-percentage-point decrease in the assumed health care
cost trend rate would decrease the net service and interest cost components of the net periodic post-retirement benefits expense by $5 and would decrease the post-retirement
benefit obligation by $45. Covance expects to make benefit payments of approximately $575 in 2004.



U.S. employees are eligible to participate in Covance's 401(k) plan, while employees in international locations are eligible to
participate in either defined
benefit or defined contribution plans, depending on the plan offered at their location. Aggregate Covance contributions to its various defined contribution plans totaled $13.5 million,
$12.3 million and $12.4 million for 2003, 2002 and 2001, respectively.

10. Stockholders' Equity



Covance is authorized to issue up to 10.0 million shares of Series Preferred Stock, par value $1.00 per share (the "Covance Series
Preferred Stock"). The
Covance Board of Directors has the authority to issue such shares from time to time, without stockholder approval, and to determine the designations, preferences, rights, including voting rights, and
restrictions of such shares, subject to the Delaware General Corporate Laws. Pursuant to this authority, the Covance Board of Directors has designated 1.0 million shares of the Covance Series
Preferred Stock as Covance Series A Preferred Stock. No other class of Covance Series Preferred Stock has been designated by the Board. As of December 31, 2003, no Covance Series
Preferred Stock has been issued or is outstanding.



Covance's Board of Directors may declare dividends on the shares of Covance common stock out of legally available funds (subject to any
preferential rights of
any outstanding Covance Series Preferred Stock). However, Covance has no present intention to declare dividends, but instead intends to retain earnings to provide funds for the operation and expansion
of its business. In addition, the Credit Facility restricts certain uses of cash such as certain restrictions on paying cash dividends on the Covance common stock.

44

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

10. Stockholders' Equity (Continued)



During 2003 the Covance Board of Directors approved a 3.0 million share buyback program. At December 31, 2003 there are
approximately
2.4 million shares remaining for purchase under this program. The following table sets forth the treasury stock activity during 2003, 2002 and 2001:

2003

2002

2001$

# shares

$

# shares

$

# sharesShares repurchased in connection with:Board approved buyback programs

$
13,515


640.3

$
16,222


1,005.0





Employee benefit plans


2,368


81.9


409


19.6

$
1,000


48.2Total

$
15,883


722.2

$
16,631


1,024.6

$
1,000


48.2




In June 2002, Covance's Board of Directors adopted the 2002 Employee Stock Option Plan (the "2002 ESOP"). The 2002 ESOP will expire
on June 24,
2012. The 2002 ESOP authorizes the Compensation and Organization Committee of the Board of Directors (the "Compensation Committee"), or such committee as is appointed by the Covance Board of
Directors, to administer the 2002 ESOP, to grant awards to employees of Covance or entities in which Covance has a controlling or significant interest, except that officers as defined in
Rule 16(a)-1(f) of the Securities Exchange Act of 1934, and members of the Board of Directors are not eligible to receive awards. The 2002 ESOP authorizes the Compensation Committee
to grant the following awards to eligible employees: options to purchase common stock and stock appreciation rights. The number of shares of Covance common stock initially available for grant under
the 2002 ESOP totaled 5.9 million. At December 31, 2003, there were approximately 4.6 million shares remaining available for grants or awards under the 2002 ESOP.

In
May 2002, Covance's shareholders approved the 2002 Employee Equity Participation Plan (the "2002 EEPP") in replacement of the 2000 Employee Equity Participation Plan (the
"2000 EEPP"). The 2002 EEPP became effective on May 7, 2002 and will expire on May 6, 2012. The 2002 EEPP authorizes the Compensation Committee, or such committee as is appointed by the
Covance Board of Directors, to administer the 2002 EEPP, to grant awards to employees and consultants of Covance or entities in which Covance has a controlling or significant interest. The 2002 EEPP
authorizes the Compensation Committee to grant the following awards to eligible employees: options to purchase common stock; stock appreciation rights; and other stock awards either singly or in
combination. The number of shares of Covance common stock initially available for grant under the 2002 EEPP totaled approximately 3.25 million plus approximately 0.9 million shares
remaining available under the 2000 EEPP at the time the 2002 EEPP was approved. Effective upon approval of the 2002 EEPP, no further grants or awards were permitted under the 2000 EEPP. All grants and
awards under the 2000 EEPP remaining outstanding are now administered and paid in accordance with the provisions of the 2000 EEPP out of shares issuable under the 2002 EEPP. At
December 31, 2003 there were approximately 4.0 million shares remaining available for grants or awards under the 2002 EEPP. Covance records compensation expense related to awards of
stock ratably over the three year vesting period, which totaled $4.2 million, $3.1 million and $1.5 million, during 2003, 2002 and 2001, respectively.

Covance
also has a noncompensatory employee stock purchase plan (the "ESPP") pursuant to which Covance may make available for sale to employees shares of its common stock at a price
equal to 85% of the

45

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

10. Stockholders' Equity (Continued)

lower
of the market value on the first or last day of each calendar quarter. The ESPP, administered by the Compensation Committee, is intended to give Covance employees the opportunity to purchase
shares of Covance common stock through payroll deductions. A maximum of 3.0 million shares may be purchased by Covance employees under the ESPP. During 2003, 2002 and 2001, a total of 156,300
shares, 166,806 shares and 329,513 shares of common stock, respectively, were issued under the ESPP. At December 31, 2003, there were approximately 1.2 million shares remaining for
purchase under the ESPP.

The
following table sets forth Covance's stock option activity during 2003, 2002 and 2001:

Number
of Shares
(in thousands)

Weighted
Average
PriceOptions outstanding, December 31, 2000


7,770.9

$
15.97Granted


284.3

$
19.16Exercised


(1,023.0
)
$
13.68Forfeited


(424.3
)
$
14.66Options outstanding, December 31, 2001


6,607.9

$
16.53Granted


1,588.3

$
17.67Exercised


(877.3
)
$
12.75Forfeited


(270.7
)
$
14.69Options outstanding, December 31, 2002


7,048.2

$
17.36Granted


1,422.9

$
22.90Exercised


(1,793.8
)
$
13.97Forfeited


(271.0
)
$
21.25Options outstanding, December 31, 2003


6,406.3

$
19.37


The
weighted average fair value of the stock options granted during 2003, calculated using the Black-Scholes option-pricing model with the assumptions as set forth in Note 2, is
$11.73 per share.

The
following table sets forth the status of all options outstanding at December 31, 2003:

Stock Options Outstanding

Stock Options ExercisableOption Price
Range

Number
of Shares
(in thousands)

Weighted
Average
Remaining
Contractual Life

Weighted
Average
Price

Number of Shares
(in thousands)

Weighted
Average
Price$
8.10-$11.22


1,054


6.6 years

$
9.79


1,049

$
9.78$
12.81-$18.98


1,747


7.3 years

$
17.37


912

$
17.13$
19.30-$22.97


2,584


6.6 years

$
21.64


1,265

$
20.38$
23.04-$29.13


1,021


5.5 years

$
26.95


942

$
27.00


At
December 31, 2003, 2002 and 2001, respectively, there were stock options exercisable of 4,168,023 shares (weighted average price of $18.50), 5,081,774 shares (weighted average
price of $17.64), and 4,583,343 shares (weighted average price of $18.86).

46

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

11. Commitments and Contingent Liabilities

Minimum annual rental commitments under non-cancelable operating leases, primarily office and laboratory facilities in effect at
December 31,
2003 are as follows:

Year ending December 31,2004

$
27,5682005

$
20,9662006

$
15,0372007

$
13,8122008

$
13,6392009 and beyond

$
46,553


Operating
lease rental expense aggregated $31.3 million, $30.1 million and $31.3 million for 2003, 2002 and 2001, respectively.

12. Segment Information

Covance has two reportable segments: early development and late-stage development. Early development services, which includes Covance's
preclinical
and Phase I clinical service capabilities, involve evaluating a new compound for safety and early effectiveness as well as evaluating the absorption, distribution, metabolism and excretion of the
compound in the human body. It is at this stage that a pharmaceutical company, based on available data, will generally decide whether to continue further development of a drug. Late-stage
development services, which include Covance's central laboratory, clinical development, periapproval, central ECG diagnostic services, and healthcare economic and reimbursement services, are geared
toward demonstrating the clinical effectiveness of a compound in treating certain diseases or conditions, obtaining regulatory approval and maximizing the drug's commercial potential.

The
information provided below is on an "as reported" basis and has not been revised to exclude the results of Biomanufacturing and Packaging, which were divested during 2001. The
information below also has not been restated to exclude special charges and goodwill amortization recorded during 2001.

47

---

COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

12. Segment Information (Continued)

The
accounting policies of the reportable segments are the same as those described in Note 2.

Early
Development

Late-Stage
Development

Other
Reconciling Items

TotalTotal revenues from external customers:2003

$
411,403

$
528,897

$
33,910  (a)

$
974,2102002

$
367,542

$
515,532

$
41,623  (a)

$
924,6972001

$
311,143

$
544,734

$
40,167  (a)

$
896,044Depreciation and amortization:2003

$
22,743

$
19,575

$
3,506  (b)

$
45,8242002

$
19,971

$
18,340

$
4,123  (b)

$
42,4342001

$
18,044

$
27,164

$
2,511  (b)

$
47,719Operating income:2003

$
83,311

$
79,227

$
(45,963)(c)

$
116,5752002

$
66,682

$
72,979

$
(44,994)(c)

$
94,6672001

$
47,963

$
33,166

$
(26,479)(c)

$
54,650Segment assets:2003

$
380,084

$
350,748

$
76,793  (d)

$
807,6252002

$
343,730

$
314,428

$
18,845  (d)

$
677,0032001

$
280,769

$
311,061

$
20,198  (d)

$
612,028Capital expenditures:2003

$
27,846

$
32,314

$
2,479  (e)

$
62,6392002

$
50,362

$
12,789

$
3,633  (e)

$
66,7842001

$
46,401

$
29,394

$
2,341  (e)

$
78,136


---

13. Geographic Information

United
States

United
Kingdom

Switzerland

Other

TotalNet revenues from external customers(1)2003

$
617,942

$
149,123

$
101,119

$
72,116

$
940,3002002

$
593,885

$
130,403

$
99,875

$
58,911

$
883,0742001

$
579,760

$
122,608

$
95,140

$
58,369

$
855,877Long-lived assets(2)2003

$
173,086

$
66,334

$
30,093

$
14,900

$
284,4132002

$
176,098

$
60,230

$
10,347

$
11,732

$
258,4072001

$
162,208

$
46,497

$
10,330

$
9,057

$
228,092


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48

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COVANCE INC. AND SUBSIDIARIES
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
DECEMBER 31, 2003, 2002 AND 2001
(Dollars in thousands, unless otherwise indicated)

14. Subsequent Event (Unaudited)

During the two month period ended February 27, 2004, Covance purchased into treasury approximately 1.2 million shares of its common stock for the
aggregate cost of $35.2 million, pursuant to a 3.0 million share buyback program authorized by Covance's Board of Directors in February 2003.

49

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Item 9. Changes in and Disagreements with Accountants on Accounting and Financial Disclosure.

None

Item 9a. Controls and Procedures.

Evaluation of disclosure controls and procedures. The Company's Principal Executive Officer and Principal Financial Officer have reviewed
and evaluated the
effectiveness of the Company's disclosure controls and procedures as of the end of the period covered in this report. Based on that evaluation, the Principal Executive Oficer and the Principal
Financial Officer have concluded that the Company's current disclosure controls and procedures are effective. There have been no significant changes in the Company's internal controls or in the other
factors that significantly affect those controls.

50

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PART III

Item 10.    Directors and Executive Officers of the Registrant

(a)   Identification
of Directors and Code of Ethics for Financial Professionals.

Incorporated
by reference to the Company's definitive Proxy Statement in connection with its 2004 Annual Meeting of Shareholders to be held on April 29, 2004, which Proxy
Statement is intended to be filed not later than 120 days after December 31, 2003, pursuant to Regulation 14A under the Securities and Exchange Act of 1934, as amended.

(b)   Identification
of Officers.

Christopher
A. Kuebler, 50, has been Covance's Chairman and Chief Executive Officer since November 1994. From November 1994 to November 2001, Mr. Kuebler was
also President of Covance. From March 1993 through November 1994, he was the Corporate Vice President, European Operations for Abbott Laboratories Inc. ("ALI"), a diversified
health care company. From January 1991 until March 1993, Mr. Kuebler was the Vice President, Sales and Marketing for ALI's Pharmaceutical Division. Mr. Kuebler has been a
member of the Covance Board since November 1994, and was elected Chairman in November 1996. Mr. Kuebler is a director of Inhale Therapeutic Systems, Inc., a biotechnology
company.

Joseph
L. Herring, 48, has been Covance's President and Chief Operating Officer since November 2001. Mr. Herring was Corporate Senior Vice President and
PresidentEarly Development Services from September 1999 to November 2001. From September 1996 to September 1999, Mr. Herring was Corporate Vice
President and General Manager of Covance Laboratories North America. Prior to joining Covance, Mr. Herring was Vice President of Caremark International, a provider of home care and physician
practice management services, and he also served as a Vice President of Baxter International where he was employed for 14 years.

William
E. Klitgaard, 50, has been Covance's Corporate Senior Vice President, Chief Financial Officer and Treasurer since September 2000. From September 1999 to
September 2000, Mr. Klitgaard had been Covance's Corporate Vice President, Strategy and Corporate Development and Treasurer. From October 1996 to September 1999,
Mr. Klitgaard was Covance's Corporate Vice President and Treasurer. Prior to that, Mr. Klitgaard was Treasurer at Kenetech Corporation in San Francisco, and prior to that
Mr. Klitgaard spent eleven years in positions of increasing responsibility with Consolidated Freightways Inc.

James
A. Bannon, 50, has been Covance's Corporate Senior Vice President and PresidentClinical and Periapproval Services since April 2002. Prior to that,
Mr. Bannon was Covance's Corporate Vice PresidentPeriapproval Services. Mr. Bannon is a director of Bio-Imaging Technologies, Inc., a medical imaging
technology company.

Michael
Giannetto, 41, has been Covance's Controller since July 1996 and a Corporate Vice President since February 1998. From November 1996 to February 1998,
Mr. Giannetto was a Vice President of Covance. From March 1995 to July 1996, Mr. Giannetto was the Business Controller for Covance. From December 1992 to
March 1995, Mr. Giannetto was the Manager of Financial Reporting and Technical Accounting for Corning Life Sciences Inc., an affiliate of the Company prior to December 31,
1996. Prior to December 1992, Mr. Giannetto was a Senior Audit Manager for Deloitte & Touche.

Donald
Kraft, 44, has been Covance's Corporate Senior Vice PresidentHuman Resources since July 2002. From January 2001 to June 2002, Mr. Kraft
was Corporate Vice PresidentHuman Resources of Covance. From June 2000 to January 2001, Mr. Kraft was Director, Organizational Development of Zurich Financial
Services, an insurance company. Prior to June 2000, Mr. Kraft was Director, Organizational Effectiveness of Abbott Laboratories.

51

---

James
W. Lovett, 39, has been Covance's Corporate Senior Vice President, General Counsel and Secretary since February 2003. From December 2001 to February 2003,
Mr. Lovett was Corporate Vice President, General Counsel and Secretary of Covance. From 1997 to 2001, Mr. Lovett was with FMC Corporation, a manufacturer of machinery and chemicals for
industry and agriculture, most recently as Associate General Counsel and Assistant Secretary. Prior to that, Mr. Lovett was a partner at the law firm of McDermott, Will & Emery.

Howard
Moody, 53, joined Covance in February 2000, as Corporate Senior Vice President and Chief Information Officer. Prior to joining Covance, Mr. Moody was Vice
President, Information Systems, Core Business for Quest Diagnostics Inc., a position to which Mr. Moody was appointed after Smithkline Beecham Clinical Laboratories was acquired by Quest
in 1999. Mr. Moody held that position with Smithkline Beecham Clinical Laboratories from 1995 to 1999. From 1989 to 1995 Mr. Moody held various positions of increasing responsibility
with Smithkline Beecham.

Stephen
J. Sullivan, 57, joined Covance in June 1999 and has been Covance's Corporate Senior Vice President and PresidentGlobal Central Laboratory Services since
May 2002. From September 1999 through April 2002, Mr. Sullivan was Corporate Senior Vice President and President-Clinical Support Services. From 1996 to 1999,
Mr. Sullivan was Chairman of the Board, President and Chief Executive Officer of Xenometrix, Inc., a Boulder, Colorado-based biotechnology company. Prior to that, Mr. Sullivan was
Vice President, Worldwide Marketing for the Diagnostics Division, and Vice President and General Manager of the Diagnostic Assay Sector of Abbott Laboratories. Mr. Sullivan was Chairman of the
Board of Xenometrix, Inc. prior to the sale of that company in May 2001.

Item 11.    Executive Compensation

Incorporated by reference to the Company's definitive Proxy Statement in connection with its 2004 Annual Meeting of Shareholders to be
held on April 29,
2004, which Proxy Statement is intended to be filed not later than 120 days after December 31, 2003, pursuant to Regulation 14A under the Securities Exchange Act of 1934, as
amended.

Item 12.    Security Ownership by Certain Beneficial Owners and Management of Covance

Information on security ownership by certain beneficial owners and management of Covance is incorporated by reference to the Company's
definitive Proxy Statement
in connection with its 2004 Annual Meeting of Shareholders to be held on April 29, 2004, which Proxy Statement is intended to be filed not later than 120 days after December 31,
2003 pursuant to Regulation 14A under the Securities Exchange Act of 1934, as amended.

Covance
maintains the Covance Inc. 2002 Employee Equity Participation Plan, the Covance Inc. 2002 Employee Stock Option Plan, the Employee Stock Purchase Plan, the Stock
Option Plan for Non-Employee Directors and the Restricted Stock Plan for Non-Employee Directors, and the Deferred Stock Unit Plan for Non-Employee Members of the
Board of Directors, pursuant to which it may grant equity awards to eligible persons.

The
following table gives information about equity awards under Covance's above mentioned plans. The only plans mentioned above which have not received shareholder approval are the
Covance Inc. 2002 Employee Stock Option Plan and the Employee Stock Purchase Plan. For a description of the material features of these plans, please see Note 10 to the Audited
Consolidated Financial Statements included elsewhere in this Annual Report.

52

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Equity Compensation Plan Information

Plan Category

Number of securities to be issued
upon exercise of outstanding
options, warrants and rights
(a)

Weighted-average exercise
price of outstanding options,
warrants and rights
(b)

Number of securities remaining
available for future issuance under
equity compensation plans
(excluding securities reflected in
column (a))Equity compensation
    plans approved by
    security holders


5,135,619

$
18.58


4,799,637Equity compensation
    plans not approved by
    security holders


1,270,700

$
22.52


5,826,954
1TOTAL


6,406,319

$
19.37


10,626,591
1


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Item 13.    Certain Relationships and Related Transactions

Incorporated by reference to the Company's definitive Proxy Statement in connection with its 2004 Annual Meeting of Shareholders to be
held on April 29,
2004, which Proxy Statement is intended to be filed not later than 120 days after December 31, 2003, pursuant to Regulation 14A under the Securities Exchange Act of 1934, as
amended.

Item 14.    Principal Accountant Fees and Services

Incorporated by reference to the Company's definitive Proxy Statement in connection with its 2004 Annual Meeting of Shareholders to be
held on April 29,
2004, which Proxy Statement is intended to be filed not
later than 120 days after December 31, 2003, pursuant to Regulation 14A under the Securities Exchange Act of 1934, as amended.

PART IV

Item 15.    Exhibits, Financial Statement Schedules and Reports on Form 8-K

(a) Documents filed as part of this report.

1.

Financial Statements.The financial statements filed as part of this report are listed on the Index to Consolidated Financial Statements on page 25.2.

Financial Statement Schedules.Schedules are omitted because they are not applicable or the required information is shown in the consolidated financial statements or notes
thereto.3.

Exhibits.The exhibits required by Item 601 of Regulation S-K filed as part of, or incorporated by reference in, this report are listed in (c) below and in the accompanying
Exhibit Index.


(b) Reports on Form 8-K.

During the three month period ended December 31, 2003, one Current Report on Form 8-K was filed. The report dated
October 22,
2003, was filed reporting the issuance of a press release of Covance's financial results for the quarter ended September 30, 2003.

(c) Item 601 Exhibits.

53

---

EXHIBIT

ExhibitNumber

Description2.1

Transaction Agreement among Corning Incorporated, Corning Life Sciences Inc., Corning Clinical Laboratories Inc. (Delaware), Covance Inc. and Corning Clinical Laboratories Inc. (Michigan), dated November 22, 1996.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 1996.3.1

Certificate of Incorporation.Incorporated by reference to Covance's filing on Amendment No. 2 on Form 10, filed with the SEC on November 19, 1996.3.2

By-Laws.Incorporated by reference to Covance's filing on Amendment No. 2 on Form 10, filed with the SEC on November 19, 1996.4.1

Form of Common Stock Certificate.Incorporated by reference to Covance's filing on Amendment No. 3 on Form 10, filed with the SEC on November 25, 1996.4.2

Rights Agreement between Covance Inc. and Harris Trust and Savings Bank, dated December 31, 1996.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December
31, 1997.10.1

Tax Sharing Agreement among Corning Incorporated, Corning Clinical Laboratories Inc. and Covance Inc., dated December 31, 1996.Incorporated by reference to Covance's Annual Report on Form 10-K for
the fiscal year ended December 31, 1996.10.2

Spin-Off Tax Indemnification Agreement between Corning Incorporated and Covance Inc., dated December 31, 1996.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year
ended December 31, 1996.10.3

Spin-Off Tax Indemnification Agreement between Covance Inc. and Corning Clinical Laboratories Inc., December 31, 1996.Incorporated by reference to Covance's Annual Report on Form 10-K for the
fiscal year ended December 31, 1996.10.4

Spin-Off Tax Indemnification Agreement between Corning Clinical Laboratories Inc. and Covance Inc., dated December 31, 1996.Incorporated by reference to Covance's Annual Report on Form 10-K for the
fiscal year ended December 31, 1996.10.5

Employee Stock Ownership Plan.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 1996.10.6

Stock Purchase Savings Plan, as amended.Incorporated by reference to Covance's Registration Statement on Form S-8 filed with the SEC on March 5, 2002.10.7

Amended and Restated Supplemental Executive Retirement Plan.Incorporated by reference Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 2002.10.8

Restricted Share Plan.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 1996.10.9

Non-Employee Directors' Amended and Restated Restricted Stock Plan.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 1998.10.10

Directors' Deferred Compensation Plan, as amended.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 1997.10.11

Conversion Equity Plan.Incorporated by reference to Covance's filing on a Registration Statement on Form S-8, Registration No. 333-29467, filed with the SEC on June 18, 1997.10.12

Non-Employee Directors' Stock Option Plan.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 1998.10.13

Deferred Stock Unit Plan for Non-Employee Members of the Board of Directors.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31,
1998.10.14

2000 Employee Equity Participation Plan.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 1999.10.15

Letter Agreement between Covance Inc. and Stephen J. Sullivan.Incorporated by reference to Covance's Quarterly Report on Form 10-Q for the period ended March 31, 2000.


54

---

EXHIBIT

ExhibitNumber

Description10.16

Letter Agreement between Covance Inc. and Joseph L. Herring.Incorporated by reference to Covance's Quarterly Report on Form 10-Q for the period ended June 30, 2000.10.17

Asset and Stock Purchase Agreement, dated as of December 21, 2000 among Covance Inc., Covance Clinical and Periapproval Services Ltd., and Fisher Scientific International, Inc.Incorporated by
reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 2000.10.18

Credit Agreement among Covance Inc., Lenders named Therein, Bank of America, N.A., Barclays Bank PLC, PNC Bank, National Association, The Bank of Nova Scotia and Bank of Tokyo-Mitsubishi Trust Company dated June 28, 2001.Incorporated by reference to Covance's Quarterly Report on Form 10-Q for the period ended June 30, 2001.10.19

Stock Purchase Agreement between Covance Inc. and Akzo Nobel Inc. dated as of April 23, 2001.Incorporated by reference to Covance's Quarterly Report on Form 10-Q for the period ended June 30,
2001.10.20

Covance Inc. Variable Compensation Plan.Incorporated by reference to Covance's Quarterly Report on Form 10-Q for the period ended September 30, 2001.10.21

Employment Agreement between Covance Inc. and Christopher A. Kuebler dated November 7, 2001.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31,
2001.10.22

Letter Agreement between Covance Inc. and Joseph Herring dated November 7, 2001.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31,
2001.10.23

2002 Employee Equity Participation Plan.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 2001.10.24

2002 Employee Stock Option Plan.Incorporated by reference to Covance's Registration Statement on Form S-8 filed with the SEC on July 31, 2002.10.25

Letter Agreement between Covance Inc. and James A. Bannon dated May 7, 2002.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31,
2002.10.26

Letter Agreement between Covance Inc. and Donald Kraft dated June 25, 2002.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31,
2002.10.27

Employee Stock Purchase Plan, as amended.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 2002.10.28

Covance Inc. Variable Compensation Plan, as amended.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 2002.10.29

Restricted Unit Plan for Non-Employee Members of the Board of Directors.Incorporated by reference to Covance's Quarterly Report on Form 10-Q for the period ended June 30, 2003.10.30

Letter Agreement between Covance and James Lovett dated March 3, 2003.Filed herewith.10.31

Covance Inc. Variable Compensation Plan effective January 1, 2004.Filed herewith.21

Subsidiaries.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 2001.23.1

Consent of Ernst & Young LLP.Filed herewith.31.1

Certification of Chief Executive Officer pursuant to SEC Rule 13(a)-14(a).Filed herewith.31.2

Certification of Chief Financial Officer pursuant to SEC Rule 13(a)-14(a).Filed herewith.32.1

Certification of Chief Executive Officer pursuant to 18 U.S.C. Section 1350.Filed herewith.32.2

Certification of Chief Financial Officer pursuant to 18 U.S.C. Section 1350.Filed herewith.


(d) Financial Statement Schedules.

None.

55

---

SIGNATURES

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, Covance has duly caused this report to be signed on its behalf
by the undersigned, thereunto duly authorized.

COVANCE INC.Dated: March 5, 2004

By:

/s/  Christopher A. KueblerChristopher A. Kuebler
Chairman of the Board and Chief Executive Officer


Pursuant
to the requirements of the Securities Exchange Act of 1934, this report has been signed below by the following persons on behalf of Covance and in the capacities and on the
dates indicated.

Signature

Title

Date/s/  Christopher A. KueblerChristopher A. Kuebler

Chairman of the Board, Chief Executive Officer and Director (Principal Executive Officer)

March 5, 2004/s/  William E. KlitgaardWilliam E. Klitgaard

Corporate Senior Vice President and Chief Financial Officer (Principal Financial Officer)

March 5, 2004/s/  Michael GiannettoMichael Giannetto

Corporate Vice President and Controller
(Principal Accounting Officer)

March 5, 2004/s/  Robert BarchiRobert Barchi

Director

March 5, 2004/s/  Robert M. BaylisRobert M. Baylis

Director

March 5, 2004/s/  Sandra L. HeltonSandra L. Helton

Director

March 5, 2004/s/  Irwin LernerIrwin Lerner

Director

March 5, 2004/s/  J. Randall MacDonaldJ. Randall MacDonald

Director

March 5, 2004/s/  Kathleen G. MurrayKathleen G. Murray

Director

March 5, 2004/s/  William C. UghettaWilliam C. Ughetta

Director

March 5, 2004


56

---

EXHIBIT INDEX

ExhibitNumber

Description2.1

Transaction Agreement among Corning Incorporated, Corning Life Sciences Inc., Corning Clinical Laboratories Inc. (Delaware), Covance Inc. and Corning Clinical Laboratories Inc. (Michigan), dated November 22, 1996.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 1996.3.1

Certificate of Incorporation.Incorporated by reference to Covance's filing on Amendment No. 2 on Form 10, filed with the SEC on November 19, 1996.3.2

By-Laws.Incorporated by reference to Covance's filing on Amendment No. 2 on Form 10, filed with the SEC on November 19, 1996.4.1

Form of Common Stock Certificate.Incorporated by reference to Covance's filing on Amendment No. 3 on Form 10, filed with the SEC on November 25, 1996.4.2

Rights Agreement between Covance Inc. and Harris Trust and Savings Bank, dated December 31, 1996.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December
31, 1997.10.1

Tax Sharing Agreement among Corning Incorporated, Corning Clinical Laboratories Inc. and Covance Inc., dated December 31, 1996.Incorporated by reference to Covance's Annual Report on Form 10-K for
the fiscal year ended December 31, 1996.10.2

Spin-Off Tax Indemnification Agreement between Corning Incorporated and Covance Inc., dated December 31, 1996.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year
ended December 31, 1996.10.3

Spin-Off Tax Indemnification Agreement between Covance Inc. and Corning Clinical Laboratories Inc., December 31, 1996.Incorporated by reference to Covance's Annual Report on Form 10-K for the
fiscal year ended December 31, 1996.10.4

Spin-Off Tax Indemnification Agreement between Corning Clinical Laboratories Inc. and Covance Inc., dated December 31, 1996.Incorporated by reference to Covance's Annual Report on Form 10-K for the
fiscal year ended December 31, 1996.10.5

Employee Stock Ownership Plan.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 1996.10.6

Stock Purchase Savings Plan, as amended.Incorporated by reference to Covance's Registration Statement on Form S-8 filed with the SEC on March 5, 2002.10.7

Amended and Restated Supplemental Executive Retirement Plan.Incorporated by reference Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 2002.10.8

Restricted Share Plan.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 1996.10.9

Non-Employee Directors' Amended and Restated Restricted Stock Plan.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 1998.10.10

Directors' Deferred Compensation Plan, as amended.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 1997.10.11

Conversion Equity Plan.Incorporated by reference to Covance's filing on a Registration Statement on Form S-8, Registration No. 333-29467, filed with the SEC on June 18, 1997.10.12

Non-Employee Directors' Stock Option Plan.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 1998.10.13

Deferred Stock Unit Plan for Non-Employee Members of the Board of Directors.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31,
1998.10.14

2000 Employee Equity Participation Plan.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 1999.10.15

Letter Agreement between Covance Inc. and Stephen J. Sullivan.Incorporated by reference to Covance's Quarterly Report on Form 10-Q for the period ended March 31, 2000.10.16

Letter Agreement between Covance Inc. and Joseph L. Herring.Incorporated by reference to Covance's Quarterly Report on Form 10-Q for the period ended June 30, 2000.


---

EXHIBIT INDEX (Continued)

ExhibitNumber

Description10.17

Asset and Stock Purchase Agreement, dated as of December 21, 2000 among Covance Inc., Covance Clinical and Periapproval Services Ltd., and Fisher Scientific International, Inc.Incorporated by
reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 2000.10.18

Credit Agreement among Covance Inc., Lenders named Therein, Bank of America, N.A., Barclays Bank PLC, PNC Bank, National Association, The Bank of Nova Scotia and Bank of Tokyo-Mitsubishi Trust Company dated June 28, 2001.Incorporated by reference to Covance's Quarterly Report on Form 10-Q for the period ended June 30, 2001.10.19

Stock Purchase Agreement between Covance Inc. and Akzo Nobel Inc. dated as of April 23, 2001.Incorporated by reference to Covance's Quarterly Report on Form 10-Q for the period ended June 30,
2001.10.20

Covance Inc. Variable Compensation Plan.Incorporated by reference to Covance's Quarterly Report on Form 10-Q for the period ended September 30, 2001.10.21

Employment Agreement between Covance Inc. and Christopher A. Kuebler dated November 7, 2001.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31,
2001.10.22

Letter Agreement between Covance Inc. and Joseph Herring dated November 7, 2001.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31,
2001.10.23

2002 Employee Equity Participation Plan.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 2001.10.24

2002 Employee Stock Option Plan.Incorporated by reference to Covance's Registration Statement on Form S-8 filed with the SEC on July 31, 2002.10.25

Letter Agreement between Covance Inc. and James A. Bannon dated May 7, 2002.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31,
2002.10.26

Letter Agreement between Covance Inc. and Donald Kraft dated June 25, 2002.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31,
2002.10.27

Employee Stock Purchase Plan, as amended.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 2002.10.28

Covance Inc. Variable Compensation Plan, as amended.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 2002.10.29

Restricted Unit Plan for Non-Employee Members of the Board of Directors.Incorporated by reference to Covance's Quarterly Report on Form 10-Q for the period ended June 30, 2003.10.30

Letter Agreement between Covance and James Lovett dated March 3, 2003.Filed herewith.10.31

Covance Inc. Variable Compensation Plan effective January 1, 2004.Filed herewith.21

Subsidiaries.Incorporated by reference to Covance's Annual Report on Form 10-K for the fiscal year ended December 31, 2001.23.1

Consent of Ernst & Young LLP.Filed herewith.31.1

Certification of Chief Executive Officer pursuant to SEC Rule 13(a)-14(a).Filed herewith.31.2

Certification of Chief Financial Officer pursuant to SEC Rule 13(a)-14(a).Filed herewith.32.1

Certification of Chief Executive Officer pursuant to 18 U.S.C. Section 1350.Filed herewith.32.2

Certification of Chief Financial Officer pursuant to 18 U.S.C. Section 1350.Filed herewith.


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