15598 Federal Register / Vol. 80, No. 56 / Tuesday, March 24, 2015 / Notices 

Washington, DC 20460; telephone 

number: 202–564–0628; fax number: 

202–564–1177; email address: 

monger.jon@epa.gov. 

SUPPLEMENTARY INFORMATION: 

Supporting documents which explain in 

detail the information that the EPA will 

be collecting are available in the public 

docket for this ICR. The docket can be 

viewed online at www.regulations.gov 

or in person at the EPA Docket Center, 

WJC West, Room 3334, 1301 

Constitution Ave. NW., Washington, 

DC. The telephone number for the 

Docket Center is 202–566–1744. For 

additional information about EPA’s 

public docket, visit http://www.epa.gov/ 

dockets. 

Pursuant to section 3506(c)(2)(A) of 

the PRA, EPA is soliciting comments 

and information to enable it to: (i) 

Evaluate whether the proposed 

collection of information is necessary 

for the proper performance of the 

functions of the Agency, including 

whether the information will have 

practical utility; (ii) evaluate the 

accuracy of the Agency’s estimate of the 

burden of the proposed collection of 

information, including the validity of 

the methodology and assumptions used; 

(iii) enhance the quality, utility, and 

clarity of the information to be 

collected; and (iv) minimize the burden 

of the collection of information on those 

who are to respond, including through 

the use of appropriate automated 

electronic, mechanical, or other 

technological collection techniques or 

other forms of information technology, 

e.g., permitting electronic submission of 

responses. EPA will consider the 

comments received and amend the ICR 

as appropriate. The final ICR package 

will then be submitted to OMB for 

review and approval. At that time, EPA 

will issue another Federal Register 

notice to announce the submission of 

the ICR to OMB and the opportunity to 

submit additional comments to OMB. 

Abstract: EPA is seeking to collect 

information from potential cellulosic 

biofuel producers to aid in determining 

the annual volume standards. This ICR 

includes a questionnaire form to 

facilitate the collection of this 

information. EPA would also like to use 

a data form to collect information from 

certain ethanol producers and importers 

who have requested and been approved 

to use an ‘‘efficient producer’’ pathway. 

This data form would standardize 

collection of selected data points and 

allow better and more efficient 

compliance with the RFS program. We 

inform respondents that they may assert 

claims of business confidentiality (CBI) 

for information they submit in 

accordance with 40 CFR 2.203. 

Forms: RFS Efficient Producer Data 

Form, RFS Cellulosic Biofuel Producer 

Questionnaire Form. 

Respondents/affected entities: 

Producers, Importers of Renewable 

Fuels. 

Respondent’s obligation to respond: 

RFS Cellulosic Biofuel Producer 

Questionnaire Form is voluntary; RFS 

Efficient Producer Data Form is 

mandatory pursuant to Sections 114 and 

208 of the Clean Air Act (CAA), 42 

U.S.C. 7414 and 7542. 

Estimated number of respondents: 80 

(total). 

Frequency of response: Annually (RFS 

Cellulosic Biofuel Producer 

Questionnaire Form) or quarterly (RFS 

Efficient Producer Data Form). 

Total estimated burden: 560 hours 

(per year). Burden is defined at 5 CFR 

1320.03(b). 

Total estimated cost: $63,840 (per 

year). 

Changes in estimates: There is no 

previous ICR for this collection. 

Dated: March 17, 2015. 

Karl Simon, 

Director, Transportation and Climate 

Division, Office of Transportation and Air 

Quality. 

[FR Doc. 2015–06770 Filed 3–23–15; 8:45 am] 

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ENVIRONMENTAL PROTECTION 

AGENCY 

[EPA–HQ–OPP–2015–0130; FRL–9923–73] 

FIFRA Scientific Advisory Panel; 

Notice of Public Meeting 

AGENCY: Environmental Protection 

Agency (EPA). 

ACTION: Notice. 

SUMMARY: There will be a 3–day meeting 

of the Federal Insecticide, Fungicide, 

and Rodenticide Act Scientific Advisory 

Panel (FIFRA SAP) to consider and 

review research to evaluate the potential 

for juvenile sensitivity to pyrethroids. 

DATES: The meeting will be held on May 

19–21, 2015, from approximately 9:00 

a.m. to 5:00 p.m. 

Comments. The Agency encourages 

written comments be submitted on or 

before May 5, 2015, and requests for oral 

comments be submitted on or before 

May 12, 2015. However, written 

comments and requests to make oral 

comments may be submitted until the 

date of the meeting, but anyone 

submitting written comments after May 

5, 2015, should contact the Designated 

Federal Official (DFO) listed under FOR

FURTHER INFORMATION CONTACT. For 

additional instructions, see Unit I.C. of 

the SUPPLEMENTARY INFORMATION. 

Nominations. Nominations of 

candidates to serve as ad hoc members 

of FIFRA SAP for this meeting should 

be provided on or before April 7, 2015. 

Webcast. This meeting may be 

webcast. Please refer to the FIFRA SAP 

Web site at http://www.epa.gov/scipoly/ 

sap for information on how to access the 

webcast. Please note that the webcast is 

a supplementary public process 

provided only for convenience. If 

difficulties arise resulting in webcasting 

outages, the meeting will continue as 

planned. 

Special accommodations. For 

information on access or services for 

individuals with disabilities, and to 

request accommodation of a disability, 

please contact the DFO listed under FOR

FURTHER INFORMATION CONTACT at least 

10 days prior to the meeting to give EPA 

as much time as possible to process 

your request. 

ADDRESSES: Meeting: The meeting will 

be held at the Environmental Protection 

Agency, Conference Center, Lobby 

Level, One Potomac Yard (South Bldg.), 

2777 S. Crystal Dr., Arlington, VA 

22202. 

Comments. Submit your comments, 

identified by docket identification (ID) 

number EPA–HQ–OPP–2015–0130, by 

one of the following methods: 

• Federal eRulemaking Portal: http:// 

www.regulations.gov. Follow the online 

instructions for submitting comments. 

Do not submit electronically any 

information you consider to be 

Confidential Business Information (CBI) 

or other information whose disclosure is 

restricted by statute. 

• Mail: OPP Docket, Environmental 

Protection Agency Docket Center (EPA/ 

DC), (28221T), 1200 Pennsylvania Ave. 

NW., Washington, DC 20460–0001. 

• Hand Delivery: To make special 

arrangements for hand delivery or 

delivery of boxed information, please 

follow the instructions at http:// 

www.epa.gov/dockets/contacts.html. 

Additional instructions on commenting 

or visiting the docket, along with more 

information about dockets generally, is 

available at 

http://www.epa.gov/dockets. 

Nominations, requests to present oral 

comments, and requests for special 

accommodations. Submit nominations 

to serve as ad hoc members of FIFRA 

SAP, requests for special 

accommodations, or requests to present 

oral comments to the DFO listed under 

FOR FURTHER INFORMATION CONTACT. 

FOR FURTHER INFORMATION CONTACT: Fred 

Jenkins, DFO, Office of Science 

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Federal Register / Vol. 80, No. 56 / Tuesday, March 24, 2015 / Notices 15599 

Coordination and Policy (7201M), 

Environmental Protection Agency, 1200 

Pennsylvania Ave. NW., Washington, 

DC 20460–0001; telephone number: 

(202) 564–3327; email address: 

jenkins.fred@epa.gov. 

SUPPLEMENTARY INFORMATION: 

I. General Information 

A. Does this action apply to me? 

This action is directed to the public 

in general. This action may, however, be 

of interest to persons who are or may be 

required to conduct testing of chemical 

substances under the Federal Food, 

Drug, and Cosmetic Act (FFDCA) and 

FIFRA. Since other entities may also be 

interested, the Agency has not 

attempted to describe all the specific 

entities that may be affected by this 

action. 

B. What should I consider as I prepare 

my comments for EPA? 

1. Submitting CBI. Do not submit CBI 

information to EPA through 

regulations.gov or email. If your 

comments contain any information that 

you consider to be CBI or otherwise 

protected, please contact the DFO listed 

under FOR FURTHER INFORMATION

CONTACT to obtain special instructions 

before submitting your comments. 

2. Tips for preparing your comments. 

When preparing and submitting your 

comments, see the commenting tips at 

http://www.epa.gov/dockets/ 

comments.html. 

C. How may I participate in this 

meeting? 

You may participate in this meeting 

by following the instructions in this 

unit. To ensure proper receipt by EPA, 

it is imperative that you identify docket 

ID number EPA–HQ–OPP–2015–0130 in 

the subject line on the first page of your 

request. 

1. Written comments. The Agency 

encourages written comments be 

submitted, using the instructions in 

ADDRESSES and Unit I.B., on or before 

May 5, 2015, to provide FIFRA SAP the 

time necessary to consider and review 

the written comments. Written 

comments are accepted until the date of 

the meeting, but anyone submitting 

written comments after May 5, 2015, 

should contact the DFO listed under FOR

FURTHER INFORMATION CONTACT. Anyone 

submitting written comments at the 

meeting should bring 30 copies for 

distribution to FIFRA SAP. 

2. Oral comments. The Agency 

encourages each individual or group 

wishing to make brief oral comments to 

FIFRA SAP submit their request to the 

DFO listed under FOR FURTHER

INFORMATION CONTACT on or before May 

12, 2015, in order to be included on the 

meeting agenda. Requests to present oral 

comments will be accepted until the 

date of the meeting and, to the extent 

that time permits, the Chair of FIFRA 

SAP may permit the presentation of oral 

comments at the meeting by interested 

persons who have not previously 

requested time. The request should 

identify the name of the individual 

making the presentation, the 

organization (if any) the individual will 

represent, and any requirements for 

audiovisual equipment. Oral comments 

given before the FIFRA SAP are limited 

to approximately 5 minutes unless prior 

arrangements have been made. In 

addition, each speaker should bring 20 

copies of his or her comments and 

presentation for distribution to FIFRA 

SAP at the meeting. 

3. Seating at the meeting. Seating at 

the meeting will be open and on a firstcome basis. 

4. Request for nominations to serve as 

ad hoc members of FIFRA SAP for this 

meeting. As part of a broader process for 

developing a pool of candidates for each 

meeting, FIFRA SAP staff routinely 

solicits the stakeholder community for 

nominations of prospective candidates 

for service as ad hoc members of FIFRA 

SAP. Any interested person or 

organization may nominate qualified 

individuals to be considered as 

prospective candidates for a specific 

meeting. Individuals nominated for this 

meeting should have expertise in one or 

more of the following areas: In vitro to 

in vivo extrapolation (IVIVE), Risk 

assessment, Toxicokinetics, 

Quantitative modeling and analyses of 

complex data, Pyrethroid pesticides, 

Age-dependent pharmacokinetics and 

metabolism, Enzyme maturation profiles 

in rodents and humans, Voltage-gated 

sodium channels, Ontogeny of 

metabolizing enzymes (e.g., 

carboxylesterase and P450), Clinical 

observations of neurotoxicology in 

animals (adult and neonate). Nominees 

should be scientists who have sufficient 

professional qualifications, including 

training and experience, to be capable of 

providing expert comments on the 

scientific issues for this meeting. 

Nominees should be identified by name, 

occupation, position, address, email 

address, and telephone number. 

Nominations should be provided to the 

DFO listed under FOR FURTHER

INFORMATION CONTACT on or before April 

7, 2015. The Agency will consider all 

nominations of prospective candidates 

for this meeting that are received on or 

before that date. However, final 

selection of ad hoc members for this 

meeting is a discretionary function of 

the Agency. 

The selection of scientists to serve on 

FIFRA SAP is based on the function of 

the Panel and the expertise needed to 

address the Agency’s charge to the 

Panel. No interested scientists shall be 

ineligible to serve by reason of their 

membership on any other advisory 

committee to a Federal department or 

agency or their employment by a 

Federal department or agency, except 

EPA. Other factors considered during 

the selection process include 

availability of the potential Panel 

member to fully participate in the 

Panel’s reviews, absence of any conflicts 

of interest or appearance of lack of 

impartiality, independence with respect 

to the matters under review, and lack of 

bias. Although financial conflicts of 

interest, the appearance of lack of 

impartiality, lack of independence, and 

bias may result in disqualification, the 

absence of such concerns does not 

assure that a candidate will be selected 

to serve on FIFRA SAP. Numerous 

qualified candidates are identified for 

each Panel. Therefore, selection 

decisions involve carefully weighing a 

number of factors including the 

candidates’ areas of expertise and 

professional qualifications and 

achieving an overall balance of different 

scientific perspectives on the Panel. In 

order to have the collective breadth of 

experience needed to address the 

Agency’s charge for this meeting, the 

Agency anticipates selecting 

approximately 10 ad hoc scientists. 

FIFRA SAP members are subject to 

the provisions of 5 CFR part 2634– 

Executive Branch Financial Disclosure, 

Qualified Trusts, and Certificates of 

Divestiture, as supplemented by EPA in 

5 CFR part 6401. In anticipation of this 

requirement, prospective candidates for 

service on FIFRA SAP will be asked to 

submit confidential financial 

information which shall fully disclose, 

among other financial interests, the 

candidate’s employment, stocks, and 

bonds, and where applicable, sources of 

research support. EPA will evaluate the 

candidates financial disclosure form to 

assess whether there are financial 

conflicts of interest, appearance of a 

lack of impartiality, or any prior 

involvement with the development of 

the documents under consideration 

(including previous scientific peer 

review) before the candidate is 

considered further for service on FIFRA 

SAP. Those who are selected from the 

pool of prospective candidates will be 

asked to attend the public meetings and 

to participate in the discussion of key 

issues and assumptions at these 

meetings. In addition, they will be asked 

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15600 Federal Register / Vol. 80, No. 56 / Tuesday, March 24, 2015 / Notices 

to review and to help finalize the 

meeting minutes. The list of FIFRA SAP 

members participating at this meeting 

will be posted on the FIFRA SAP Web 

site at http://www.epa.gov/scipoly/sap 

or may be obtained from the OPP Docket 

at http://www.regulations.gov. 

II. Background 

A. Purpose of FIFRA SAP 

FIFRA SAP serves as the primary 

scientific peer review mechanism of 

EPA’s Office of Chemical Safety and 

Pollution Prevention (OCSPP) and is 

structured to provide scientific advice, 

information and recommendations to 

the EPA Administrator on pesticides 

and pesticide-related issues as to the 

impact of regulatory actions on health 

and the environment. FIFRA SAP is a 

Federal advisory committee established 

in 1975 under FIFRA that operates in 

accordance with requirements of the 

Federal Advisory Committee Act (5 

U.S.C. Appendix). FIFRA SAP is 

composed of a permanent panel 

consisting of seven members who are 

appointed by the EPA Administrator 

from nominees provided by the National 

Institutes of Health and the National 

Science Foundation. FIFRA established 

a Science Review Board (SRB) 

consisting of at least 60 scientists who 

are available to FIFRA SAP on an ad hoc 

basis to assist in reviews conducted by 

FIFRA SAP. As a scientific peer review 

mechanism, FIFRA SAP provides 

comments, evaluations, and 

recommendations to improve the 

effectiveness and quality of analyses 

made by Agency scientists. Members of 

FIFRA SAP are scientists who have 

sufficient professional qualifications, 

including training and experience, to 

provide expert advice and 

recommendation to the Agency. 

B. Public Meeting 

The Federal Insecticide, Fungicide, 

and Rodenticide Act (FIFRA) authorizes 

EPA to register pesticides and the 

FFDCA gives the agency the authority to 

establish tolerances for residues 

resulting on food and/or feed resulting 

from use of a pesticide. The studies 

required to allow the agency to make the 

appropriate statutory safety findings 

under both of these acts are stipulated 

under 40 CFR part 158. There is 

flexibility, however, in implementing 

Part 158. Additional data can be 

required (§ 158.75), alternative 

approaches can be accepted, and studies 

can be waived (§ 158.45). The 2007 

National Research Council (NRC) report 

from the National Academy of Sciences 

(NAS) on Toxicity Testing in the 21st 

Century describes this new vision for 

toxicity testing. In response to the NRC 

report, EPA’s Office of Pesticide 

Programs (OPP) developed a Strategic 

Direction for New Pesticide Testing and 

Assessment Approaches http:// 

www.epa.gov/pesticides/science/testingassessment.html which describes OPP’s 

approach to implementing the NAS 

vision. One of the key components of 

OPP’s Strategic Direction is improved 

approaches to more traditional toxicity 

tests to minimize the number of animals 

used while expanding the amount of 

information obtained. OPP also has a 

recent document, Guiding Principles for 

Data Requirements (http:// 

www.epa.gov/pesticides/regulating/ 

data-require-guide-principle.pdf) which 

describes the principles for requiring 

toxicology data for pesticides, 

specifically to ‘‘only require data that 

adequately inform regulatory decision 

making and thereby avoid unnecessary 

use of time and resources, data 

generation costs, and animal testing.’’ 

OPP is actively working on a 

reevaluation of the human health effects 

of the pyrethroids and pyrethrins under 

the OPP registration review program 

(http://www.epa.gov/oppsrrd1/ 

registration_review/index.htm), required 

under FIFRA. 

Until late 2009, OPP requested 

developmental neurotoxicity (DNT) 

studies for pyrethroids. However, the 

agency determined that the DNT studies 

were not providing adequate data to 

evaluate the potential for post-natal 

sensitivity to pyrethroids. In July, 2010, 

the FIFRA Scientific Advisory Panel 

(SAP) reviewed a proposed research 

strategy to assess the potential for 

juvenile sensitivity consistent with the 

recommendations of the NAS in its 

report on Toxicity Testing in the 21st 

Century using a combination of in vitro 

studies, targeted in vivo studies, and 

physiologically-based pharmacokinetic 

(PBPK) models. 

Based on feedback from the SAP and 

the agency, the industry research 

proposal was revised. Since late 2010, 

the Council for the Advancement of 

Pyrethroid Human Health Risk 

Assessment (CAPHRA) has worked with 

industry and academic scientists to 

develop assays and models to assess the 

potential for juvenile post-natal 

sensitivity to pyrethroids. The on-going 

research effort is organized around the 

adverse outcome pathway (AOP) for 

pyrethroids: Alterations with voltagegated sodium channels (VGSC), leading 

to alterations in membrane excitability 

and firing potentials and ultimately to in 

vivo clinical syndromes. Specifically, 

the CAPHRA is evaluating the potency 

of pyrethroids to human sodium 

channels and transplantation of adult 

and juvenile rat synaptic membrane into 

oocytes. In addition, the CAPHRA is 

conducting targeted in vivo studies on 

behavioral metrics and developing 

PBPK models. The research, thus far, 

has focused on development of the 

overall approach using data for 

deltamethrin and permethrin (Type II 

and Type I pyrethroids, respectively). 

The CAPHRA research is at a point 

where feedback on extending this 

research to the other pyrethroids would 

be constructive. The CAPHRA proposal 

is to use the knowledge gained with 

deltamethrin and permethrin to develop 

more targeted datasets using read across 

and computational approaches (i.e., less 

data generation) for other pyrethroids. 

As such, the agency will be seeking the 

SAP’s advice on the current state of the 

science with the CAPHRA research 

effort and proposals for next steps 

which include extension of data on 

deltamethrin and permethrin to other 

pyrethroids. 

C. FIFRA SAP Documents and Meeting 

Minutes 

EPA’s background paper, related 

supporting materials, charge/questions 

to FIFRA SAP, FIFRA SAP composition 

(i.e., members and ad hoc members for 

this meeting), and the meeting agenda 

will be available by approximately 4 

weeks before the meeting. In addition, 

the Agency may provide additional 

background documents as the materials 

become available. You may obtain 

electronic copies of these documents, 

and certain other related documents that 

might be available at http:// 

www.regulations.gov and the FIFRA 

SAP Web site at http://www.epa.gov/ 

scipoly/sap. 

FIFRA SAP will prepare meeting 

minutes summarizing its 

recommendations to the Agency 

approximately 90 days after the 

meeting. The meeting minutes will be 

posted on the FIFRA SAP Web site or 

may be obtained from the OPP Docket 

at http://www.regulations.gov. 

Authority: 7 U.S.C. 136 et seq.; 21 U.S.C. 

301 et seq. 

Dated: March 13, 2015. 

David J. Dix, 

Director, Office of Science Coordination and 

Policy. 

[FR Doc. 2015–06689 Filed 3–23–15; 8:45 am] 

BILLING CODE 6560–50–P 

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