Initial to indicate certification as to information on this page

(full text of certification is on page one).

Date

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. 

Use additional sheet(s) if necessary.

2. Case # and Name 3. Date and Type of DCI and Number

4. EPA Product 

Registration

5. I wish to cancel 

this product 

registration 

voluntarily

6. Generic Data 7. Product Specific Data

6a. I am claiming a Generic Data 

Exemption because I obtain the 

active ingredient from the source 

EPA registration number listed 

below.

6b. I agree to satisfy Generic Data

Requirements as indicated on the 

attached form entitled 

"Requirements Status and 

Registrant's Response."

7a. My product is an MUP and I 

agree to satisfy the MUP 

requirement on the attached form

entitled "Requirements Status and

Registrant's Response."

7b. My product is an EUP and I 

agree to satisfy the EUP 

requirement on the attached form 

entitled "Requirements Status and 

Registrant's Response."

OMB Approval 2070-0174

1. Company Name and Address

0106 - Ethoprop

Chemical # and Name: 041101

Ethoprop

24-Jun-2010

GENERIC

ID # GDCI-041101-876

United States Environmental Protection Agency

Washington, D.C. 20460

DATA CALL-IN RESPONSE

Page of 1 1

8. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

Signature and Title of Company's Authorized Representative ______________________________________________________

10. Name of Company

N/A N/A

9. Date

11. Phone Number 
Initial to indicate certification as to information on this page (full text of certification is on page one) Date

13. Phone Number

10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any 

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

12. Name of Company

11. Date

OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________

Post-Application Exposure Data Requirements (Conventional 

Chemical)

Terrestrial and Aquatic Nontarget Organisms Data 

Requirements (Conventional Chemical)

Toxicology Data Requirements (Conventional Chemical)

875.2400

875.2500

850.1500

850.2300

870.3465

870.7800

Dermal exposure

Inhalation exposure

Fish life cycle toxicity

Avian reproduction test

90-day inhalation toxicity

Immunotoxicity

0106 - Ethoprop

Chemical # and Name: 041101

Ethoprop

24-Jun-2010

GENERIC

ID # GDCI-041101-876

C,A,B

C,A,B

C,A,B

C,A,B

C,A,B

C,A,B

TEP

TEP

TGAI

TGAI

TGAI

TGAI

24

24

24

24

24

12

Page 1 of 

(4, 6, 9, 10, 

11)

(4, 5, 9, 12)

(2, 8)

(1, 7)

(3, 13)

Y

Y

N

N

Y

N

1
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

0106 - Ethoprop

GDCI-041101-876

1

2

3

4

5

6

7

8

9

10

11

12

13

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

This study is required for the mallard duck species.

This study is required for the freshwater species.

Required if there is the likelihood of significant repeated inhalation exposure to the pesticide as a gas, vapor, or aerosol.

Protocols must be submitted for approval prior to the initiation of the study. Details for developing protocols are available from the Agency.

Post-application inhalation exposure to ethoprop is predicted to occur during the mechanical transplanation of sugarcane. The proposed protocol should account for typical agricultural practices

associated with sugarcane.

Post-application dermal exposure to ethoprop is predicted to occur during the mechanical transplanation of sugarcane. The proposed protocol should account for typical agricultural practices 

associated with sugarcane.

Data using the TGAI are required to support all outdoor end-use product uses including, but not limited to turf. Data are generally not required to support end-use products in the form of a gas, a 

highly volatile liquid, a highly reactive solid, or a highly corrosive material.

Data are required on freshwater species if the end-use product is intended to be applied directly to water, or is expected to be transported to water from the intended use site, and when any of

the following conditions apply:

i. If the estimated environmental concentration (EEC) is=0.1 of the no-observed-effect level in the fish early-life stage or invertebrate life cycle test;

ii. If studies of other organisms indicate that the reproductive physiology of fish may be affected.

Data are required for occupational sites if the human activity data indicate that workers are likely to have post-application exposures while participating in typical activities.

Bridging applicable residue dissipation data to dermal exposure is required.

Biological monitoring data may be submitted in addition to, or in lieu of, dermal and inhalation exposure data provided the human pharmocokinetics of the pesticide and/or metabolite/analog 

compounds (i.e., whichever method is selected as an indicator of body burden or internal dose) allow for a back-calculation to the total internal dose.

Biological monitoring data may be submitted in addition to, or in lieu of, dermal and inhalation exposure data provided the human pharmocokinetics of the pesticide and/or metabolite/analog 

compounds (i.e., whicheve method is selected as an indicator of body burden or internal dose) allow for a back-calculation to the total internal dose.

Because only short- and intermediate-term occupational exposure durations are expected and long-term, chronic exposures are not expected based on current ethoprop labels, a 28-day 

inhalation toxicity study may be sufficient to assess cholinesterase inhibition and satisfy this requirement. If the registrant wishes to perform a 28-day rather than the standard 90-day inhalation

toxicity study, they should submit a protocol and consult with the Agency prior to initiating the study to ensure the study design is acceptable.

Case # and Name:

DCI Number:

Page: 1 of 1

Footnotes: The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. 

These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement.

Use Categories Key:

A - Terrestrial food crop

B - Terrestrial feed crop

C - Terrestrial nonfood crop
United States Environmental Protection Agency 

Washington, D.C. 20460

LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICE

Case # and Name: 0106 - Ethoprop

Page: 1 of 1

264 BAYER CROPSCIENCE LP

Co. Nr. Company Name Agent For Company

2 T.W. ALEXANDER DRIVE, P.O. Box 12014

Address City ZIP

RESEARCH TRIANGLE PARK 27709

OMB Approval 2070-0174

State

NC

 DCI Number: GDCI-041101-876
LINKS TO FORMS:

The pesticide registration forms that are listed below can be found at:

http://www.epa.gov/opprd001/forms/

Link to Confidential Statement of Formula and Instructions (Form # 8570-4)

http://www.epa.gov/opprd001/forms/8570-4.pdf

Certification of Attempt to Enter Into an Agreement With Registrants for 

Development of Data (Form # 8570-32)

http://www.epa.gov/opprd001/forms/8570-32.pdf

Certification With Respect to Citation of Data (Form # 8570-34)

http://www.epa.gov/opprd001/forms/8570-34.pdf