Initial to indicate certification as to information on this page (full text of certification is on page one). Date INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary. 2. Case # and Name 3. Date and Type of DCI and Number

4. EPA Product Registration 5. I wish to cancel this product registration voluntarily 6. Generic Data 7. Product Specific Data 6a. I am claiming a Generic Data Exemption because I obtain the active ingredient from the source EPA registration number listed below. 6b. I agree to satisfy Generic Data Requirements as indicated on the attached form entitled "Requirements Status and Registrant's Response." 7a. My product is an MUP and I agree to satisfy the MUP requirement on the attached form entitled "Requirements Status and Registrant's Response." 7b. My product is an EUP and I agree to satisfy the EUP requirement on the attached form entitled "Requirements Status and Registrant's Response." OMB Approval 2070-0174

1. Company Name and Address 0106 - Ethoprop Chemical # and Name: 041101 Ethoprop 24-Jun-2010 GENERIC ID # GDCI-041101-876 

### United States Environmental Protection Agency

Washington, D.C. 20460 DATA CALL-IN RESPONSE 1 Page of 1

8. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law. Signature and Title of Company's Authorized Representative ______________________________________________________ 10. Name of Company N/A N/A

9. Date

11. Phone NumberDate Initial to indicate certification as to information on this page (full text of certification is on page one) 13. Phone Number 10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.
12. Name of Company 11. Date OMB Approval 2070-0174 

### United States Environmental Protection Agency

Washington, D.C. 20460 REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline Requirement Number 5. Study Title Progress Reports



### 2 3 1 6. Use

Pattern 7. Test Substance 8. Time Frame (Months) 9. Registrant

Response P R O T O C O L 1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________

Post-Application Exposure Data Requirements (Conventional Chemical)

Terrestrial and Aquatic Nontarget Organisms Data Requirements (Conventional Chemical)

Toxicology Data Requirements (Conventional Chemical) 875.2400 875.2500

850.1500 850.2300

870.3465 870.7800 Dermal exposure

Inhalation exposure

Fish life cycle toxicity Avian reproduction test
90-day inhalation toxicity Immunotoxicity 0106 - Ethoprop Chemical # and Name: 041101 Ethoprop 24-Jun-2010 GENERIC ID # GDCI-041101-876

C,A,B C,A,B

C,A,B C,A,B

C,A,B C,A,B TEP TEP

TGAI TGAI

TGAI TGAI 24 24

24 24

24 12 1 of Page

(4, 6, 9, 10, 11) (4, 5, 9, 12)

(2, 8) (1, 7)
(3, 13) Y

Y

N N

Y N 1

### United States Environmental Protection Agency Washington, D.C. 20460 FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS 0106 - Ethoprop GDCI-041101-876

1 2 3 4 5 6 7 8

9 10 11 12 13 Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

This study is required for the mallard duck species. This study is required for the freshwater species. Required if there is the likelihood of significant repeated inhalation exposure to the pesticide as a gas, vapor, or aerosol. Protocols must be submitted for approval prior to the initiation of the study. Details for developing protocols are available from the Agency. Post-application inhalation exposure to ethoprop is predicted to occur during the mechanical transplanation of sugarcane. The proposed protocol should account for typical agricultural practices associated with sugarcane. Post-application dermal exposure to ethoprop is predicted to occur during the mechanical transplanation of sugarcane. The proposed protocol should account for typical agricultural practices associated with sugarcane. Data using the TGAI are required to support all outdoor end-use product uses including, but not limited to turf. Data are generally not required to support end-use products in the form of a gas, a highly volatile liquid, a highly reactive solid, or a highly corrosive material. Data are required on freshwater species if the end-use product is intended to be applied directly to water, or is expected to be transported to water from the intended use site, and when any of the following conditions apply: i. If the estimated environmental concentration (EEC) is=0.1 of the no-observed-effect level in the fish early-life stage or invertebrate life cycle test; ii. If studies of other organisms indicate that the reproductive physiology of fish may be affected. Data are required for occupational sites if the human activity data indicate that workers are likely to have post-application exposures while participating in typical activities. Bridging applicable residue dissipation data to dermal exposure is required. Biological monitoring data may be submitted in addition to, or in lieu of, dermal and inhalation exposure data provided the human pharmocokinetics of the pesticide and/or metabolite/analog compounds (i.e., whichever method is selected as an indicator of body burden or internal dose) allow for a back-calculation to the total internal dose. Biological monitoring data may be submitted in addition to, or in lieu of, dermal and inhalation exposure data provided the human pharmocokinetics of the pesticide and/or metabolite/analog compounds (i.e., whicheve method is selected as an indicator of body burden or internal dose) allow for a back-calculation to the total internal dose. Because only short- and intermediate-term occupational exposure durations are expected and long-term, chronic exposures are not expected based on current ethoprop labels, a 28-day inhalation toxicity study may be sufficient to assess cholinesterase inhibition and satisfy this requirement. If the registrant wishes to perform a 28-day rather than the standard 90-day inhalation toxicity study, they should submit a protocol and consult with the Agency prior to initiating the study to ensure the study design is acceptable. Case # and Name: DCI Number: 1 Page: of 1

Footnotes: The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement. Use Categories Key: A - Terrestrial food crop B - Terrestrial feed crop C - Terrestrial nonfood crop

### United States Environmental Protection Agency Washington, D.C. 20460 LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICE 0106 - Ethoprop Case # and Name: 1 Page: of 1

264 BAYER CROPSCIENCE LP Co. Nr. Company Name Agent For Company 2 T.W. ALEXANDER DRIVE, P.O. Box 12014 Address City ZIP RESEARCH TRIANGLE PARK 27709 OMB Approval 2070-0174

State NC DCI Number: GDCI-041101-876

# LINKS TO FORMS: The pesticide registration forms that are listed below can be found at: http://www.epa.gov/opprd001/forms/ Link to C onfidential Statement of Formula and Instructions (Form # 8570 -4 

# ) http://www.epa.gov/opprd001/forms/8570 - 4.pdf C ertification of Attempt to Enter Into an Agreement With Registrants for Development of Data (Form # 8570 - 32 

# ) http://www.epa.gov/opprd001/forms/8570 - 32.pdf
C ertification With Respect to Citation of Data (Form # 8570 - 34 

# ) http://www.epa.gov/opprd001/forms/8570 - 34.pdf