Initial to indicate certification as to information on this page (full text of certification is on page one). Date INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary. 2. Case # and Name 3. Date and Type of DCI and Number

4. EPA Product Registration 5. I wish to cancel this product registration voluntarily 6. Generic Data 7. Product Specific Data 6a. I am claiming a Generic Data Exemption because I obtain the active ingredient from the source EPA registration number listed below. 6b. I agree to satisfy Generic Data Requirements as indicated on the attached form entitled "Requirements Status and Registrant's Response." 7a. My product is an MUP and I agree to satisfy the MUP requirement on the attached form entitled "Requirements Status and Registrant's Response." 7b. My product is an EUP and I agree to satisfy the EUP requirement on the attached form entitled "Requirements Status and Registrant's Response." OMB Approval 2070-0174

1. Company Name and Address N/A - Cyromazine Chemical # and Name: 121301 Cyromazine 17-Sep-2008 GENERIC ID # GDCI-121301-844 

### United States Environmental Protection Agency

Washington, D.C. 20460 DATA CALL-IN RESPONSE 1 Page of 1

8. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law. Signature and Title of Company's Authorized Representative ______________________________________________________ 10. Name of Company N/A N/A

9. Date

11. Phone NumberDate Initial to indicate certification as to information on this page (full text of certification is on page one) 13. Phone Number 10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.
12. Name of Company 11. Date OMB Approval 2070-0174 

### United States Environmental Protection Agency

Washington, D.C. 20460 REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline Requirement Number 5. Study Title Progress Reports



### 2 3 1 6. Use

Pattern 7. Test Substance 8. Time Frame (Months) 9. Registrant

Response P R O T O C O L 1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________

Product Chemistry Data Requirements (Conventional Chemical)
Terrestrial and Aquatic Nontarget Organisms Data Requirements (Conventional Chemical)

Toxicology Data Requirements (Conventional Chemical) 830.7050

850.1025 850.1350

870.3465 UV/Visible absorption

Oyster acute toxicity test (shell deposition) Mysid chronic toxicity test
90-day inhalation toxicity N/A - Cyromazine Chemical # and Name: 121301 Cyromazine 17-Sep-2008 GENERIC ID # GDCI-121301-844

R,C,A,B

R,C,A,B R,C,A,B

R,C,A,B TGAI/PAI

TGAI, TEP TGAI

TGAI 8

12 12

24 1 of Page

(2, 3, 6) (4, 5)
(1, 7) N

N N

N 1

### United States Environmental Protection Agency Washington, D.C. 20460 FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS N/A - Cyromazine GDCI-121301-844

1 2

3 4

5 6 7 Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

Required if there is the likelihood of significant repeated inhalation exposure to the pesticide as a gas, vapor, or aerosol. Freshwater fish LC50 (the most sensitive of the species tested), freshwater invertebrate EC50 (preferably Daphnia), and acute LC50/EC50 estuarine and marine organisms studies using the EP or TEP are required for any product which meets any of the following conditions: (i) The end-use pesticide will be introduced directly into an aquatic environment (e.g., aquatic herbicides and mosquito larvicides) when used as directed; (ii) the maximum expected environmental concentration (MEEC) or the estimated environmental concentration (EEC) in the aquatic environment is equal to or greater than one-half the LC50 or EC50 of the TGAI when the EP is used as directed; (iii) an ingredient in the end-use formulation other than the active ingredient is expected to enhance the toxicity of the active ingredient or to cause toxicity to aquatic organisms. Data using the TGAI are required to support all outdoor end-use product uses including turf. Data are generally not required to support end use products in the form of a gas, a highly volatile liquid, a highly reactive solid, or a highly corrosive material. Data are required on estuarine species if the product is: (i) intended for direct application to the estuarine or marine environment; (ii) expected to enter this environment in significant concentrations because of its expected use or mobility patterns, and (iii) if the acute LC50 or EC50 < 1 mg/l; or (iv) if the estimated environmental concentration in water is equal to or greater than 0.01 of the acute EC50 or LC50 and any of the following conditions exist: (a) studies of other organisms indicate the reproductive physiology of fish and/or invertebrates may be affected; (b) physicochemical properties indicate bioaccumulation of the pesticide; (c) the pesticide is persistent in water (e.g., half-life in water greater than 4 days). Data are preferred on oppossum shrimp (America mysis) formerly (Mysidopsis bahia). Data are preferred on eastern oyster (Crassostrea virginica) and oppossum shrimp (America mysis) formerly (Mysidopsis bahia) and silver side (Menidia sp.) Based on estimates of the magnitude and duration of human exposure, studies of shorter duration, e.g., 21 or 28-days, may be sufficient to satisfy this requirement. Registrants should consult with the Agency to determine whether studies of shorter duration would meet this requirement. Case # and Name: DCI Number: 1 Page: of 1

Footnotes: The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement. Use Categories Key: A - Terrestrial food crop B - Terrestrial feed crop C - Terrestrial nonfood crop R - Agricultural premises and equipment

### United States Environmental Protection Agency Washington, D.C. 20460 LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICE N/A - Cyromazine Case # and Name: 1 Page: of 1

70585 75066 100 NOVARTIS ANIMAL HEALTH US, INC.

NOVIL, INC. SYNGENTA CROP PROTECTION, LLC Co. Nr. Company Name Agent For Company

NOVIL, INC. 3200 NORTHLINE AVENUE, SUITE 300 1020 INDUSTRIAL DRIVE, P.O. Box 28 410 SWING ROAD, P.O. Box 18300 Address City ZIP GREENSBORO WATKINSVILLE GREENSBORO 27408 30677 274198300 OMB Approval 2070-0174

State NC GA NC DCI Number: GDCI-121301-844

# LINKS TO FORMS: The pesticide registration forms that are listed below can be found at: http://www.epa.gov/opprd001/forms/ Link to C onfidential Statement of Formula and Instructions (Form # 8570 -4 

# ) http://www.epa.gov/opprd001/forms/8570 - 4.pdf C ertification of Attempt to Enter Into an Agreement With Registrants for Development of Data (Form # 8570 - 32 

# ) http://www.epa.gov/opprd001/forms/8570 - 32.pdf C ertification With Respect to Citation of Data (Form # 8570 - 34 

# ) http://www.epa.gov/opprd001/forms/8570 - 34.pdf