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# Incidence and Cost of Carbon Monoxide Poisoning for All Ages, Pool and Spa Submersions for Ages 0−14,

and Lead Poisoning for Ages 0−4

Final Report
Task Order 1, CPSC Contract D- 09 -0003 Ted Miller, Soma Bhattacharya

March 28, 2013

This report is being posted on the CPSC website for public comment. The recommendations are those of the contractor and may not reflect the views of CPSC staff.
This report has not been reviewed or approved by , and may not necessarily reflect the views of, the Commission.

### i 

# Table of Contents

Introduction ..................................................................................................................................... 1
Data Sets and Diagnosis/Cause Codes Used .............................................................................. 1

Incidence ......................................................................................................................................... 4
Lead Poisoning............................................................................................................................ 4
CO Poisoning .............................................................................................................................. 6

Submersion ............................................................................................................................... 11

Work Loss Costs ........................................................................................................................... 17
Lead Poisoning.......................................................................................................................... 17
CO Poisoning ............................................................................................................................ 19

Submersion ............................................................................................................................... 20
Quality of Life Loss ...................................................................................................................... 23
Lead Poisoning.......................................................................................................................... 26
CO Poisoning ............................................................................................................................ 27

Submersion ............................................................................................................................... 29

Future Research ........................................................................................................................ 29
Summary ....................................................................................................................................... 30

References ..................................................................................................................................... 31
Appendix A: Other Costs of Lead Poisoning ............................................................................... 36
Appendix B: Narrative Descriptors for International Classification of Disease Codes and NEISS Codes Included.............................................................................................................................. 42

Codes from the 10 th 

### Edition of ICD, http://apps.who.int/classifications/icd10/browse/2010/en (r egardless of medical treatment, multiple cause of death data typically include both a diagnosis code and an external cause code) .............................................................................. 42
Diagnosis Codes........................................................................................................................ 42ii



# Tables
Table 1. Incidence of Lead Poisoning at Ages 0-4 by Survival and Data Source .......................... 4

Tab le 2. Medically Attended Nonfatal Lead Poisonings by Case Disposition and Data Source ... 5
Table 3. Incidence of Carbon Monoxide Poisoning by Survival and Data Source ........................ 6
Table 4. Medically Attended Nonfatal Carbon Monoxide Poisoning by Case Disposition and Data Source ..................................................................................................................................... 8
Table 5. Incidence of Carbon Monoxide Poisoning Treated with Hyperbaric Oxygen (HBO 2 

### ), 1992−2002 ...................................................................................................................................... 9
Table 6. Incidence of Submersion by Survival and Data Source ................................................. 11
Table 7. Medically Attended Nonfatal Submersions by Case Disposition and Data Source ....... 12
Table 8. Mean Hospital Costs per Admission for Carbon Monoxide Poisoning, All Ages; Lead Poisoning, Ages 0−4, and Submersions, Ages 0−14, HCUP-NIS, 2007 ...................................... 15
Table 9. Mean Hospital Costs per Carbon Monoxide Poisoning Admission by Disposition, HCUP-NIS, 2007 .......................................................................................................................... 15
Table 10. Mean Hospital Costs per Lead Poisoning Admission by Disposition, HCUP-NIS, 2007

................................ ....................................................................................................................... 15
Table 11. Mean Hospital Costs per Submersion Admission by Disposition, HCUP-NIS, 2007.. 16
Table 12. IQ Points and Resulting Percentage of Earnings Lost by Blood Lead Level ............... 18
Table 13. Adverse Health Effects and Estimated Veteran’s Administration Disability Costs of Adult Lead Exposure by Blood Lead Level, in 2007 Dollars ....................................................... 19
Table 14. Short-Term Wage Loss and Percentage of Lifetime Earnings Lost to Traumatic Brain Injury by Abbreviated Injury Scale (AIS) Threat to Life Severity ............................................... 21
Table 15. Short-Term Household Production Loss and Percentage of Lifetime Household Production Lost to Traumatic Brain Injury by Abbreviated Injury Scale (AIS) Threat to Life Severity ......................................................................................................................................... 22
Table 16. Health Utility Index 2 Estimates of Utility Loss for Brain Injury by Functional Impact

................................ ....................................................................................................................... 24
Table 17. Utility Loss Associated with Retardation ..................................................................... 25
Table 18. Acute Symptoms in 1144 Patients with Carbon Monoxide Poisoning ......................... 27iii



### Table 19. Probability of Neurocognitive Sequelae of Carbon Monoxide Poisoning by Treatment Mode and Time Post-Exposure ..................................................................................................... 28
Table 20. Costs per Police-Reported Crime by Cost Category in 2010 Dollars........................... 39
Table 21. Percentage of Crimes Reported, Percentage of Reported Crimes that Lead to an Arrest, and Number of Arrests in 2010 ..................................................................................................... 40
Table 22. Annual Arrest Rate and Estimated Crimes Committed per Person by Age Range, 2010, and Estimated Annual Violent and Property Crime Costs Over Different Age Ranges per 5 μg/dl Rise in Blood Lead Level at Age 0−4 (in 2010 dollars) ............................................................... 41

### 1 

# Introduction

The U.S. Consumer Product Safety Commission ’s (CPSC’s) major tool for estimating the
b enefits from prevention of injuries related to consumer products is its Injury Cost Model (ICM). CPSC developed the ICM in the late 1970s and continues to refine it. The ICM provides a common basis for measuring the dollar burden of a wide range of product-related injuries. Used in conjunction with injury and fatality data, the ICM permits the CPSC to compare alternative poli cies designed to reduce consumer product injuries and evaluate the relationships of their
costs and benefits.

T he CPSC periodically i nvestigates issues related to swimming pool and spa submersion, lead poisoning, and carbon monoxide (CO) poisoning b ecause of their frequency and severity

. These injuries are primarily brain injuries with rare
, but potentially serious long

- term neurologica l sequelae. Le ad poisoning also adversely affects other body systems. Unlike traumatic brain injuries (TBIs) ( e.g ., from bicycle crashes or sports), t he ICM is not designed to capture these injuries . Thus
, d ata on incidence and costs of health problems res ulting from the se injuries are less complete and less reliable than for most injuries associated with consumer products. The purpose of this task order was to improve knowledge of their incidence and c osts

. Improved estimates will enhance decision making a bout relevant exposures.
CPSC’s task order request focused on unintentional nonoccupational and nonfire carbon

monox ide poisonings of victims a t all ages
, swimming pool and spa submersions of victims younger than 15 years of age , and lead poisonings of vic tims younger than 5 years of age

. The
task order called for analy ses of incidence of medically treated cases, associated work losses
, and quality

- of

- life losses
, and acute , but (due to budget constraints) not long

- term , medical care costs
for cases associa ted with products under CPSC’s jurisdiction

. Lead poisoning has other sequelae
, including increased need for special education and elevated risk of occurrence of attention deficit hyperactivity disorder (ADHD) and criminal behavior. The appendix examines t he rates and
costs of those events. 

## Data Sets and Diagnosis/Cause Codes Used We primarily used Healthcare Cost and Utilization Project (HCUP) and National Electronic Injury Surveillance System (NEISS) data. HCUP is a family of health care databases

### 2

and related software tools and products developed through a federal-state-industry partnership and sponsored by the Agency for Healthcare Research and Quality (AHRQ). We analyzed 2006
HCUP -KID (kid’s inpatient database), 2007 HCUP NIS (nationwide inpatient sample), and 2007
HCUP NEDS (nationwide emergency department (ED) sample ). 1 

### NEISS is the CPSC’s EDbased injury surveillance system. It draws data from a much smaller sample of EDs than NEDS,
but it investigates cases in far greater detail. Unlike the HCUP data sets, NEISS contains narratives that can be used to differentiate swimming pool and spa submersions from other submersions. For submersions, therefore , we also used 2008 NEISS consumer product injury and
all

- injury profile ( AIP ) data.
We obtained and incorporated data from the Undersea and Hyperbaric Medical Society (UHMS) hyperbaric oxygen treatment database (a joint project with the Centers for Disease
Control and Prevention ( CDC) ) for treatment of CO poisoning cases

. We also examined CO poisoning incide nce reported in the N ational Poison ing Data System (NPDS) operated by the
American Association of Poison Control Centers

. In the United States, mortality data are coded by diagnoses, intent, and cause/mechanism of injury/poisoning us in g International Class ification of Diseases, 10th Edition (ICD10). Hospital inpatient and emergency department discharge data are coded with this information using the older International Classification of Diseases, 9 th Edition , Clini c al Modification (ICD9

- CM). Coding of hosp ital data will move to ICD10

- CM on October 1, 2014. Appendix B
lists ICD codes used in this project.
We drew fatal and ED-treated submersion incidence and location data from published sources: the CPSC’s analysis of 2006−2008 National Vital Statistics System (NVSS) mortality
da ta ; 2008

− 2010 NEISS consumer product injury data and supplemental NEISS investigations (Gipson 2011a, 2011b) ; and the CDC’s analysis of 2005

− 2009 NVSS and NEISS

- AIP data ( Laosee et al. 2012 )

. All th ree studies searched text narratives to determine place of submersion

. Unintentional, non

- transport, nonfatal submersion injuries in NEISS and NEISS

- AIP cases were
defined as cases with NEISS injury code 6 4

. CPSC and CDC identified fatal submersions as

1 Adjustments were required for the state of Texas, which provided age categories rather than actual ages. For lead poisoning at ages 0−4, we used the Texas count of lead poisoning patients in age categories 1 and 2 (ages 0−17) times percentage of patients ages 0−4 among those ages 0−17 in all other states. We used a parallel computation for submersions.

### 3

ICD10 codes W16, W29, W65, W66, W73, W74, or Y21 and also searched narrative fields for
the te rms “drown” or “submer. ” C PSC and CDC used NEISS product codes and NEISS and
NVSS narratives to identify pool and spa submersions. (See Appendix B for ICD and NEISS codes descriptors.)
We tabulated lead poisoning fatalities (ICD10 code T56.0) with 2009 NVSS data. For CO poiso n ing, w e used a CPSC CO fatality count restricted to nonfire deaths associated with the
use of consumer products under CPSC’s jurisdiction (Hnato v 2012)

. This count started from all cases with diagnos i s code X47 or Y17. CPSC searched accompanying death certificate narratives to identify CO cases and determine their etiology. We also give a broader CO fatality count for
ICD10 diagnosis code T58
, mod ified by external cause codes X47 or Y17
, and excluding
uncontrolled fire deaths and deaths in motor vehicles. This count includes all remaining
unintentional CO deaths and an allocated portion of deaths of undetermined intent.
In analyzing hospital and ED discharges using HCUP, we excluded cases paid by
W orker’s Compensation. Among nonoccupational cases, unintentional, non-transport
, nonfire
CO poisoning cases w ere defined as cases with an ICD9

- CM external cause code between E868.2 and E868.9 or with diagn osis code 986 , as well as an external cause code of E868.1 or
E868.2. Lead poisoning was defined to be cases with diagnosis 984 and/or external cause code
E861.5 or E866.0. Submersion was defined as cases with diagnosis 994.1 and/or external cause
code E83 0, E832, or E910. ICD9

- CM does not distinguish swimming pool and spa submersions
from bathroom, bucket
, and open body of water submersions.
Lead exposure is most often chronic, not acute, without obvious symptoms. Indeed, most lead exposure cases are not medically attended or even recognized as occurring. Therefore, we also drew on national surveillance data on lead poisoning to estimate low-level exposure.

### 4 

# Incidence

As prescribed in CPSC’s task order, this chapter largely focuses on counts of the medically treated injuries used to gain insight into medical treatment cost and outcome issues. Those interested in the subset of incidents associated with consumer products under CPSC regulation should consult the CPSC reports cited below. Among medically treated nonfatal cases, submersion incidence wa s highest
, followed by CO poisoning
, and then lead poisoning.


# Lead Poisoning

Childhood lead poisoning is rarely fatal, with no fatalities under age nine in 2007

− 20 1 0

. Tables 1 and 2 present incidence of lead poisoni ng in children age s 0

− 4 both for hospital

- treated fatal and nonfatal cases, as well as for nonfatal case s , by location of disposition. These events are

rare. We recommend relying on the KID dataset for hospital

- admitted lead poisoning (and child
submersion ) incidence counts because its sample size of child cases is much larger than in the
2007 H CUP

– 

### NIS, resulting in narrower confidence intervals. The NEDS estimate of lead poisoning admi ssions

Table 1. Incidence of Lead Poisoning at Ages 0-4 by Survival and Data Source

Data

source Year Fatal or

Nonfatal Raw

Case Count Weighted

Incidence Linearized

Standard Error [95%

Confidence Interval]
NVSS 2007

-

2010 Fatal 0 0 0 0 0
NIS Inpatient Sample 2007 Non f atal 51 247 69 111 384

Fatal 0 0

NEDS ED Visit Sample 2007 Treated & Released 10 45 *
Admitted 17 84 *

Fatal 0 0 KID Child Inpatient Sample 2006 Non f atal 120 211 34 144 279

Fatal 0 0

NB: NIS (nationwide inpatient sample) and KID (kid’s inpatient database) fatality counts are restricted to patients admitted to the hospital. NEDS counts only those fatalities where the victims died in the ED. KID counts only
p atients under age 21.* Empty strata prevented variance estimation.

### 5

is 

### less reliable; it i s based on such a small count that we could not estimate its standard error. The very low count of lead poisoning cases in EDs is matched by a virtual absence of cases in doctors’ offices in National Ambulatory Medical Care Survey (NAMCS) data. NAMCS is an
annual U.S. National Center for Health Statistics survey.
During 1999

– 2004, 1.4 percent of children ages 1–5 years had blood lead levels at least
10 micrograms per deciliter ( μg/dL ) ( Jones et al.
, 2009 ). National data, collected in 2007

– 2008 (CDC, 2012), show that the median blood lead level ( BLL ) in children ages 1

– 5 years is 1.4 μg/dL ; the 95th percentile is 4.1 μg/dL. Although children with BLLs in this lower range are
unlik ely to be medically attended, as documented in the wage loss section below, low lead

exposure reduces IQ

. Table 2. Medically Attended Nonfatal Lead Poisonings by Case Disposition and Data Source

Data

source Year Age

group Dispositio n Raw Case Count Weighted

Incidence Linearized

Standard Error [95%

Confidence Interval] Hospital

- admitted
NIS 2007 0

− 4 Discharged to Home 45 220

NIS 0

− 4 Discharged to Nursing Home * 0 0

NIS 0

− 4 Discharged to Another Facility ** 0 0

NIS 0

− 4 Discharged to Home Health Care 6 28

Hospital

- admitted KID 2006 0

− 4 Discharged to Home 111 195 30 136 254
KI D 0

− 4 Discharged to Nursing Home * 0 0 0

. .

KID 0

− 4 Discharged to Home Health Care 9 16 13 0 42

Note: Missing standard error due to stratum with single nonzero sampling unit

. * Nursing home includes both skilled nursing facilities and intermediate car e facilities

. ** The definition of another facility varies by state and may include residential care, hospice facility, rehabilitation center, psychiatric hospital, or other non

- acute care.

### 6



# CO Poisoning

Table 3 presents incidence data about CO poisoning. For 2007 to 2009, based on a hand

review of death certificates, CPSC estimates unintentional nonfire CO poisoning deaths
associated with consumer products under CPSC’s jurisdiction average d 169 per year (Hnatov 2012). NVSS indicates that an average of 47 7 people per year died of unintentional CO poisoning in 2007 to 2008 (excluding deaths in uncontrolled fires and motor vehicles ). This estimate includes 14 deaths per year allocated from the undetermined intent category and 3.5 deaths per year involving ca rbon monoxide poisoning (ICD10 code T58) without codes that would indicate they were intentional or related to fires or motorized vehicles

. That suggests roughly 35 percent of unintentional CO poisoning deaths not associated with fires or motor
vehicles in volve consumer products regulated by CPSC. That same percentage might apply to
nonfatal cases. (Including intentional exposures and fi re

- related cases, CO deaths in 2007 to
20 08 totaled 3,745.) Table 3. Incidence of Carbon Monoxide Poisoning by Survival and Data Source

Data source Year Fatal or Non f atal Age

group Raw Case Count Weighted

Annual Incidence Linearized

Standard Error [95%

Confidence Interval]
NVSS + Death Certificates (Hnatov 2012) 2007

-

200 9 Fatal Consumer Pro duct All 5 08 169 12 118 221

NVSS 2007

-

2008 Fatal All 9 54 47 7 NA NA NA HCUP NIS 2007 Non f atal All 243 1,210 186 846 1,574 Inpatient Sample Fatal All 6 30 12 6 53 HCUP NEDS ED 2007 Treated & Released All 2,752 13,029 742 11,574 14,485 Visit Sample Admitted

Fatal All

All 2 83

4 1,29 6

21 11 2

11 1
, 075

0 1
, 517

43 HCUP KID Child 2006 Non f atal 0

− 20 93 153 25 105 201 Inpatient Sample Fatal 0

− 20 2 3 2 0 8

NB: NA=Not Applicable (vital statistics counts are a census ; HCUP = Healthcare Cost and Utilization Project , NIS

= nationwide inpatient sample , NEDS = nationwide emergency department sample , KID = kid’s inpatient database

. NIS and KID fatality counts are restricted to patients admitted to the hospital. NEDS fatalities died in the ED ; NEDS does not track patients beyond hospital admission.

### 7

HCUP-NIS estimates 1,210 people were discharged alive after hospital inpatient stays for unintentional nonfire CO poisoning in 2007. According to HCUP KID, 153 of those survivors

we re children. NIS and KID show that almost none of the deaths occurred in hospital inpatient units. Finally HCUP-NEDS─which is an independent sample, not a subset of NIS─estimates that more than 14,000 CO poisoning patients were treated in the ED; an estimated 1,296 of these patients were admitted to a hospital and 21 died in the ED. The remainder were treated and
relea sed. NIS estimates about 30 died in the hospital after being admitted

. It is not surprising t hat NIS and NEDS yield consistent estimates. Neither is a national probability sample. The NEDS emergency department sample (including cases admitted through the E D and cases that instead were treated and released) comes from a subset of the states that have NIS inpatient data
, although the two systems sample cases from different data sets . In states included in both data
sets, NEDS samples a much larger share of ad missions through the ED, but it misses any admissions that bypass the ED ( e.g ., if a hospital admitted the patient directly to a hyperbaric chamber) . HCUP weights both samples using the same procedures.
Table 4 shows discharge destinations for hospital-admitted CO poisoning survivors. Patients discharged to places other than home typically have lasting disability. Effects of CO poiso ning, however, are not always cle ar

- c ut during initial treatment. A fter initially appearing to have made a full recovery based on restoration of normal carboxyhemoglobin levels, even treated and released ED patients can experience delayed neurological sequelae resulting in lasting impairment. This is also true for patients treated with hyperbaric oxygen (HBO 2 

### )

. Symptoms may not m anifest until well after the patient returns home.
CO poisoning treatment generally involves administering oxygen, either normobaric (face mask at ambient pressure) or hyperbaric (high-pressure chamber). HCUP CO incidence (and related medical cost) estimates may miss some cases that receive hyperbaric oxygen
treatment. Table 5 presents incidence of CO poisoning treated in hyperbaric treatment facilities between 1992 and 2002 (Hampson and Little, 2005)

. On average, a pproximately 1
, 500 cases
, including fire

- re lated and intentional CO poisonings
, annually receive d one hyperbaric treatment, with a few receiving a second treatment. Of 1,90 7 survivors treated in a large convenience sample of 64 hyperbaric facilities between August 2008 and July 2011, 45 percent wer e treated and released ( Hampson et al.
, 20 12 )

. Those patients probably would be missed in studies relying

on hospital and ED discharge data. Wide variation s in h yperbaric facility us ag e rates between

### 8

states (Hampson et al., 2012) suggest usage probably is determined by physician preference and facility presence more than by patient health status.

In 2008, the Centers for Disease Control and Prevention (CDC) teamed with the Undersea and Hyperbaric Medical Society (UHMS) to monitor cases of carbon monoxide

po isoning treated in U

. S

. hyperbaric facilities (Hampson et al. , 20 12 ). This system went live nationally and was open voluntarily to all U

. S

. hyperbaric facilities o n August 1
, 2008. Given the
estimates from Table 5 , it probably captures around 42 percent of cases annually (636/1500). Exhibit 1 presents surveillance system data from H a mpson et al. (2012)
, showing incidence, patient demographics , and details of exposure and treatment . The se data probably were representative of hyperbaric use in their catchment areas. Importantly, 68 percent of cases were unintentional nonfire, non

- motor

- vehicle (auto or boat) cases

. Most nonoccupational cases in this
category resulted from defective furnaces and improper use of generators. Intubation often means the patient was unconscious when hyperbaric treatment began, but it may not necessarily imply a bad outcome.

Table 4. Medically Attended Nonfatal Carbon Monoxide Poisoning by Case Disposition and Data Source

Data

source Year Age

group Disposition Raw Case Count Weighted Incidence Lineari z ed

Stand ard Error [95%

Confidence Interval] Hospital

- a dmitted only
NIS 2007 All Discharged to Home 208 1029 158 719 1339

NIS All Discharged to Nursing Home 0 0

. . .

NIS All Discharged to Anoth er Facility * 22 113 31 51 174

NIS All Discharged to Home Health Care 13 68 19 32 105

Hospital

- admitted children only KID 2006 0

− 20 Discharged to Home 89 147 24 99 195
KID 0

− 20 Discharged to Nursing Home 3 4 3 0 11

KID 0

− 20 Discharged to Home Health Care 1 2 2 0 4

Note: Missing standard error due to stratum with single nonzero sampling unit

### 9

* The definition of another facility varies by state and may include residential care, hospice facility, rehabilitation center, psychiatric hospital, or other non

- acute care.
Table 5. Incidence of Carbon Monoxide Poisoning Treated with Hyperbaric Oxygen (HBO 2 ), 1992

− 2002
Year Patients w ith CO Poisoning

Annually Treated with HBO 2 1992 1291 1993 1450 1994 1502 1995 1714 1996 1684 1997 1448 1998 1492 1999 1452 2000 1441 2001 1388 2002 1505 Source: Hampson and Little (2005).

### 10

Exhibit 1. Demographic Characteristics of Carbon Monoxide Poisoning Patients in the (Voluntary) National Hyperbaric Oxygen Surveillance System, 8/1/2008

− 7/31/2011

 One thousand nine hundred seven cases were reported between August 1, 2008 and July 31, 2011.

 The six states that reported the most cases are: Utah (197), Pennsylvania (189 ), Washington (1 69), Michigan (146), Illinois (144), and Maryland (139 ).

 The incidence by gender is 1,128 males (59 %), 787 females (41 %) , including 46 pregnant

women (t otal of

1915 conflicts with other counts in Hampson et al, 2012).

 A total of 59.6 percent of cases were non-Hispanic whites.

 Among 1,513 cases responding to this question, 3.7 percent had experienced prior CO poisoning.

 Furnace (38%), generator (2 0 %) , and fire (1 3 %) were the three most common so urces of nonoccupational, non-transport-related CO poisoning cases. Together they accounted for 71 percent of those cases.

 Of known cases, 1,505 (8 5 %) were unintentional (including fire and motor vehicle), and 273 (1 5%) were intentional.

 Occupational incidents (292) accounted for 15 percent of cases.

 Virtually all cases already had been treated with normobaric oxygen.

 A total of 15.7 percent of cases were intubated.
Age Distribution (1,905 cases with known ages)

Age Group Cases Percent 0−9 167 8.8% 10− 19 203 10.7% 20− 29 279 14.6% 30− 39 295 15.5% 40− 49 362 19.0% 50− 59 275 14.4% 60− 69 170 8.9% 70− 79 92 4.8% 80−89 57 3.0% 90+ 5 0.3%
Source: Hampson et al. (20 12 ).

### 11



# Submersion

Table 6 present s submersion incidence in children age s 0

− 14
, for fatal and non

- fatal discharge s from the ED
, and Table 7 break s these cases down by place of disposition. In Table 7, ED data systems record whether children were admitted to the hospital but do not track status
post

- admission. NIS and KID show d ischarge destinations and survival for these cases. NEDS’ s estimate of child submersion cases treated and released, which comes from a much larger sample (1617 cases versus 101 for NEISS , Consumer Product Sample (CPS) and 32 for NEISS

- AIP ) and
far more EDs than the NEISS estimates, is two to three times the NEISS CPS and NEISS AIP estimates and exceeds their 95 percent confidence intervals. In contrast, admission estimates (weighted incidence) from the five data systems range from 1,951 to 2,586, with the preferred KID estimate at 2,107, including 1,914 non

- fatal discharges and 203 deaths in the hospital.

Table 6. Incidence of Submersion by Survival and Data Source

Data

source Year Fatal or

Non f atal Age

group Raw

Case Count Weighted

Incidence Linearized

Standard Error [95% Confidence

Interval]

NIS 2007 Non f

atal Inpatient 0

− 14 375 18 05 297 12 23 2 387 Inpatient Sample 2007 Fatal 0

− 14 38 178

. . . NEISS

CPS ED Consumer Product Sample 2008 Non f atal ED 0

− 14 185 4981 1616 1771 8192 NEISS

- AIP ED All Injury Sample 200 8 Uninten

tional Non f atal ED 0

− 14 103 3 5 3 6 817 1936 5136

NED S 2007 Non f ata l ED 0

− 14 2180 10083

. . . ED Sample 2007 Fatal 0

− 14 98 452

. . .

KID Child 2006 Non f atal Inpatient 0

− 14 1160 1914 135 1650 2179 Inpatient Sample 2006 Fatal 0

− 14 121 203 26 153 253

### 12

Table 7. Medically Attended Nonfatal Submersions by Case Disposition and Data Source

Data

source Year Age

group Disposition Raw Case Count Weighted Incidence Linearized

Standard Error [95%

Confidence Interval] NIS 2007 0

− 14 Admission Discharged to Home 3 65 1 755 2 89 1 18 9 23 2 2

N IS 2007 0

− 14 Discharg ed to Nursing Home or Another Facility * 0 0

. . .

NIS 2007 0

− 14 Discharg ed to Another Institution 3 14

. . .
NIS 2007 0

− 14 Discharg ed to Home Health Care 7 35

. . .
NEISS

CPS 2008 0

− 14 ED Treated & Released

- All 101 2783 895 1005 456 1

NEISS

CPS 2008 0

− 14 ED Treated & Released

- Injured a t H ome 53 1521 521 486 2555

NEISS

CPS 2008 0

− 14 Admitted thru ED

- All 84 2198 795 619 3777

NEISS

CPS 2008 0

− 14 Admitted thru ED

Injured a t H ome 49 1490 653 192 2788

NEISS

AIP 2005 0

− 14 ED Treated & Re leased

- All 32 1169 354 460 1878

NEISS

AIP 2005 0

− 14 ED Treated & Released

- Injured a t H ome 5 88 41 5 171

NEISS

AIP 2005 0

− 14 Admitted thru ED

- All 49 1951 551 848 3054

NEISS

AIP 2005 0

− 14 Admitted thru ED

Injured a t H ome 24 877 269 339 1415

NEDS 2007 0

− 14 ED Treated & Released 1617 7496

. . . NEDS 2007 0

− 14 Admitted thru ED 563 2586

. . . KID 2006 0

− 14 Admission Discharged to Home 1112 1835 130 1580 2091

KID 2006 0

− 14 Discharg ed to Nursing Home or Another Facility * 30 49 10 29 69

KID 2006 0

− 14 Disch arg ed to Home Health Care 18 30 7 16 43

Note: Missing standard error due to stratum with single nonzero sampling unit

* The definition of another facility varies by state and may include residential care, hospice facility, rehabilitation center, psychiatric hospital, or other non-acute care.

### 13

Admitted submersion cases with sequelae almost always emerge dependent on tracheotomy tubes and possibly feeding tubes. Th is means these children have expected short lifespans, cannot breathe independently, typically require round-the-clock nursing care, and are medically fragile and prone to infection.

Based on narrative record review, Laosee et al. (2012) estimate that at ages 0−4, 50.1

pe rcent of deaths a nd 64.6 percent of ED visits for submersion result from pool and spa incidents. Among nonfatal events, they estimate 45.7 percent are in private pools; 31.7 percent are in public pools; and 22.6 percent are in unspecified pools. At ages 5−14, they estimate 29.9 percent of deaths and 76.0 percent of ED visits are pool

- related submersions. The pattern among pool types differs with only 20.8 percent in private pools; 62.4 percent in public pools; and 16.8 percent in pools of unspecified type. Overall, at ages 0−14, 43.4 percent of drowning deaths and 67.8 percent of nonfatal submersions occur in pools and spas. Gipson (2011a) estimates pool and spa fatalities under age 15 averaged 383 in 2006−2008, higher than the Laosee et al. estimate of 332 per year (with place of occurrence unknown for many cases) . (Another 351 pool submersion deaths occurred annually among adults.) Gipson (2011b) further estimates 660 non

- pool an d

non

- spa submersion incidents occurred in 2005

– 2009 for children younger than 5 years old

. The se include 431 fatalities , 212 nonfatal in juries, and 17 incidents with no apparent injury or unknown injury.



## Short-Term Medical Costs

Tables 8 −1 1 present the mean costs of acute medical care for hospital admissions for the

tar get conditions. We computed costs by multiplying hospital-and-service-specific cost- to

- charge ratios developed by AHRQ times charge data on NIS. We generally did not add separately charged professional fees and post-discharge costs. CPSC’s Injury Cost Model (ICM) estimates lifetime medical costs of a hospital

- admitted nonfatal injury by multiplying acute inpatient costs times the ratio of total costs, including inpatient cos ts, professional fees, and post

- discharge
costs, to acute costs. The last column in Table 8 shows the ratios the ICM uses for CO poisoning, lead poisoning, and submersion

. the ratios of total costs

– including inpatient costs,

### 14

professional fees, and post-discharge costs

– to inpatient costs that our existing injury cost algorithm would multiply
, times hospital inpatient costs
, to estimate lifetime costs. Reliability of
those ratios is uncertain for the conditions under study. It was originally planned to a nalyze diagnosis

- specific utilization/medical payments in a claims file to provide better estimates
, but lack of funding precluded this analysis.
Among admitted cases, acute medical costs per case were highest for submersion, followed by CO poisoning, with lead poisoning much lower (Table 8). For nonfatal submersion,

we could not establish case severity because HCUP datasets lack the five-digit procedure codes needed to identify cases requiring critical care or ventilator management. Data sparseness also

pr evented us from calculating standard errors.
In 1998, average Medicare payments for a covered hyperbaric treatment of CO poisoning were approximately $405, including $140 for physician supervision and $265 for outpatient services (Office of Inspector General, 2000). Hampson and Little (2005) estimate most patients receive only one treatment.
Que st Laboratories charges the military and other volume purchasers $6−$7 for a blood lead test, with retesting indicated if blood lead level (BLL) exceeds 35−40 μg/dL. Although CDC only recommends chelation therapy if child BLL exceeds 45 μg/dL, concerns about effects of lower BLLs has increased use on lesser exposures, despite potential side effects. A single

c helation treatment usually lasts 2−4 hours. It cost $77 on average in 2007 (Nahin et al. 2009). In
the f irst month, patients typically receive 5−30 treatments, with 30 being most common (Keogh
& Boyer 2011 ). Thus, the typical cost is around $2,000.

B y design, this task order did not probe the costs of care in the post-acute period. Estimating those costs would require a longitudinal analysis of a very large claims file like a multistate Medicaid file. That analysis also would greatly improve our knowledge of the severity distribution and of survival time following catastrophic injury.

A parent gave us permission to disclose long-term medical costs of her child’s
submersion injury that occurred in California in July 1979 when he was 14 months old . He is
trach eotomy

- dependent and tube

- fed. H e spent his first year post

- injury in hospital. He then
came h ome to 24

- hour register e d nursing (RN) care at $8 per hour. The mother sued and got him
admitted to school ; the schools paid his nurse as an attendant

. He was home for 25 years with 24

-

### 15

hour nursing care . Because RNs now c ost $40/hour in C alifornia
, the mother has been forced to
shift h er son to a subacute hospital facility with costs of $18,000 per month. Consistent with this anecdote, life care planners tell us that $8 million in lifetime medical costs is typical as a pla intiff’s claim for cases related to catastrophic birth outcomes that involve similar care needs.

Table 8. Mean Hospital Costs per Admission for Carbon Monoxide Poisoning, All Ages; Lead Poisoning, Ages 0

− 4, and Submersions, Ages 0

− 1 4, HCUP-NIS, 2007

Age

group Type of Case Mean Hospital Costs ( 2007 $) Lifetime Medical Cost Multiplier *

All CO Poisoning 15,769 1.86
0

− 4 Lead Poisoning 7,857 1.73
0

− 14 Submersions 25,896 3.36 * This multiplier is the ratio of lifetime medical costs, including professional fees and post-discharge care
to acute hospital care from PIRE’s existing injury cost models. Note: Missing standard error due to stratum with single sampling unit

. Table 9. Mean Hospital Costs per Carbon Monoxide Poisoning Admission by Disposition, HCUP-NIS, 2007

Disposition Mean Hospital Costs ( 2007 $) Discharged to Home 9,657 Discharg ed to Another Institution 70,588 Discharg ed to Home Health Care 17,542
Table 10. Mean Hospital Cost s per Lead Poisoning Admission by Disposition, HCUP-NIS, 2007

Disposition Mean Hospital Costs ( 2007 $) Discharged to Home 7,131 Discharg ed to Home Health Care 13,654

### 16

Table 11. Mean Hospital Costs per Submersion Admission by Di sposition, HCUP-NIS, 2007

Disposition Mean Hospital Costs ( 2007 $) Discharged to Home 22,438 Discharg ed to Another Institution 130,346 Discharg ed to Home Health Care 156,453

### 17 

# Work Loss Costs
This section provides the present value of future productivity losses (wage work and household work) at 3 percent and 7 percent discount rates.


# Lead Poisoning
The relationship between childhood lead poisoning and subsequent IQ loss is well established in the literature. Attention originally focused on productivity losses associated with child blood lead levels (BLL) ≥ 10 μg/dl (Grosse, 2002; Gould, 2009, Needleman, 2004; Pocock

e t al., 1994; Schwartz, 1994a; Sc h wartz, 1994b ) . More recent research documents impacts of lower range BLLs of 2

− 10 μg/dl (Canfield et al., 2003 ; Lanphear et al.
, 2005)

. Lanphear et a l. (2005) is widely accepted as the definitive study (CPSC, 2012; EPA, 2006; Gould, 2009; Muennig, 2009 )

. It estimates a nonlinear relationship between increasing lead exposure and changes in IQ. “E stimated IQ point decrements associated with an increase i n blood lead from 2.4 to 10 μg/dL, 10 to 20 μg/dL, and 20 to 30 μg/dL were 3.9 (95% CI, 2.4

– 5.3), 1.9 (95% CI, 1.2

– 2.6), and 1.1 (95% CI, 0.7

– 1.5), respectively. For a given increase in blood lead, the lead

- associated intellectual decrement for children wit h a maximal blood lead level < 7.5 μg/dL was significantly greater than

. . . for those with a maximal blood lead level ≥ 7.5 μg/dL (p = 0.015). ” With adjustment for covariates, the best

- fitting model result ed in a relationship between BLL and change in IQ given by :
Change in IQ = ln(BLL)*(-2.7)

. Consistent with these findings, Chandramouli et al. (2009) established that lead poisoning adversely affects academic performance and echoed findings by Chen et al. (2007) that it causes behavioral problems. Importantly, Dietrich et al. (2004) found that chelation therapy did not

re duce the long-term neuropsychological and behavioral effects of child lead poisoning.
Muennig (2009), Grosse (2002)
, and Schwartz (1994b) ( all relying heavily on classic work by Needleman ) directly analyzed the impact of lower IQ levels on future earning potential. Like IQ impact, this relationship is relatively invariant over time. Thus, future work loss cost can

### 18

be estimated by applying their estimates of percentage impact on average potential earnings and household production per IQ point lost to CPSC’s lifetime productivity estimates by age and sex.
Muennig (2009) concludes that Schwartz (1994b) uses the soundest design for assessing the impact of lower IQ levels on future earning pote ntial . Schwartz ( 1994 b ) estimated that a one

point difference in IQ results in a 1.76 percent difference in earnings
, an estimate that also

account s for a differential rate of high school graduation

. Gross e et al. (2002) calculate that analyses in Salkever (1995) indicate the difference averages 2.37 percent , while Neal and Johnson ( 1 996) estimate t he difference averages 1.66 percent. So earnings loss for a given BLL change would be ( ln(BLL post 

### )

- ln(BLL pre 

### ) ) *(

- 2.7) * .0176 * lifetime earnings.

We recommend that the CPSC estimate productivity losses from its lifetime earnings estimates, assuming an initial BLL of one

. Table 12 shows how the loss es of IQ points
associated with various blood lead levels determine earnings losses

. The age

- earnings model
built in to the CPSC’s ICM estimates lifetime productivity at age 2 averages $939,691
, including $ 653,559 in wages and $286,132 in household production (present value at a 3 percent discount rate, in 2007 dollars). These estimates exclude productivity loss associat ed with other chronic health effects of lead exposure.

Table 12. IQ Points and Resulting Percentage of Earnings Lost by Blood Lead Level
Blood Lead Level ( ug /dL) IQ Points Lost % of Earnings Lost

2 1.9 3.3% 5 4.3 7.6% 7 5.3 9.2 % 10 6.2 10.9% 20 8.1 14.2% 30 9.2 16.2% 40 10 17.5% 50 10.6 18.6% 60 11.1 19.5% 90 12.1 21.4% 

### Earnings Loss Unrelated to IQ Loss

. Although the task order focuses on childhood lead poisoning, some cases will continue undiagnosed into adulthood for two reasons. First, chelation therapy reduces but does not eliminate blood lead. Second, some parents decline chelation.
More over, although a month of intensive treatment often is indicated, side effects or other burdens on parents and the exposed child may lead to drop out mid-course. For analyses that

### 19

need to account for enduring effects of lead exposure, Table 13 summarizes signs and symptoms by BLL. Of greater relevance, the table estimates net present value of disability payments that
the V eteran’s Administration would make to a claimant by BLL. Those payments proxy lost earnings due to the listed health effects.

T able 13. Adverse Health Effects and Estimated Veteran’s Administration Disability Costs of Adult Lead Exposure by Blood Lead Level, in 2007 Dollars

BLL (μg/dL) Signs & Symptoms Making Onset Disability Cost/VA Claim

< 10 ALAD* inhibition, linear homocysteine level rise with BLL,

nephrotoxicity, increased risk for ischemic heart disease, hypertension, and end

- stage renal d isease; decreased glomerular filtration rate; adverse pregnancy outcomes including spontaneous abortion, decreased birth weight and head circumference 15−20 Erythrocyte protoporphyrin increases, EPO inhibition; subtle, non

specific neurologic effects at 20

- 60 μg/dL $15,075

30 Increased simple reaction time, cognitive CNS deficits, anemia, †

peripheral nerve dysfunction, proteinuria, enzymuria, hypertension; changes in FSH, LH and testosterone levels; changes in immune parameters $58,685

40 Increases in u rinary ALA and coproporphyrin, sperm changes, gout,

decreased fertility. Changes in T 4 and TSH levels. Neurobehavioral changes $148,237

50 Decreased hemoglobin production, disturbed sleep, anorexia $262,915 60 Abdominal pain, arthralgia, clumsiness, vomi ting, irritability,

inability to concentrate, fatigue, diarrhea, headache, behavioral changes, inhibition of Vitamin D activity, severe renal disease with chronic exposure $374,631

80 Frank anemia $416,626 100

– 120 Ataxia, vomiting, convulsions, stupor, constipation, coma; mental

retardation, epilepsy, blindness, sterility, severe renal damage $664,017

*Abbreviations: ADD (attention deficit disorder); ALA (5 -aminolevulinic acid); ALAD (δ-aminolevulinic acid dehydratase); EPO (erythropoietin); FSH (follicle-stimulating hormone); Ig (immunoglobulin); LH (luteinizing hormone);T4 (thyroxine); TSH (thyroid stimulating hormone) †Anemia can appear at BLLs as low as 20 μg/dL, but may be more commonly associated with higher levels (50- 80 μg/dL).
Source: Compiled from various VA disability scales and coding systems and analyzed by the author. 

# CO Poisoning
Surprisingly, although many studies (reviewed in the section on quality of life loss) have analyzed longer term impairments associated with CO poisoning, a literature search did not reveal data about impact on work-related disability. Data on 92 jury verdicts in carbon monoxide cases included only three, where past wage losses were stated, with losses of $3,600, $49,947,

a nd $95,500. We gained additional insight by calling a leading forensic specialist in vocational

### 20

rehabilitation (VR), Robert Taylor. Mr. Taylor reports that brain damage severity is strongly predicted by carboxyhemoglobin level at intake and that brain damage often is diffuse and quite

se vere in its impact. We suggest a reasonable assumption might be a 15 percent loss in earning capacity (proportional to the quality of life loss estimate below) for tho se with enduring cognitive sequelae. Hampson et al. (2009) report that regardless of severity, nonfatal CO poisoning does not shorten lifespan
, although lifestyle factors cause those experiencing CO poisoning (including intentional self

- harm) to have eleva ted risks of subsequent death from suicide, violence, substance abuse, or unintentional injury.

For people w ith the age and sex distribution of CO poisoning victims from Exhibit 1, the

age

- earnings model built into CPSC’s ICM predicts lifetime productivity would average $937,815 . This includes $640,282 in wages and $297,533 in household production (present
value at a 3 percent discount rate, in 2007 dollars). A 15 percent lifetime earnings loss equates to $140,672
, including $96,042 in wages and $44,630 in household production.



# Submersion
For submersion, children with severe sequelae generally do not survive to working age, meaning their lifetime productivity is lost (Zamula, 1987). Unless the child is placed in residential care, one parent also typically will lose the majority of their productivity until the

c hild dies.
Our current injury cost model include s imperfect estimates of probability of work

- related disability for hospital

- admitted submersion survivors with moderate sequelae. The best data
avail able are the broadly based but not

- fully

- representative submersion estimates in Zamula (1987). We supplemented that information with estimates by VR specialist Robert Taylor. Cases with severe sequelae require 24

- hour skilled nursing care and greatly reduc e lifespan. Mr. Taylor
tells us that submersion cases with moderate (as opposed to severe) sequelae are rare, maybe 2
percent of those with sequelae

— and those involve substantial deficits
, even though the child is ambulatory. National Drowning Prevention A lliance Advisory Council Chair Nadina Riggsbee had similar impression s and reported that pediatricians generally tell parents that typical survival is 6 years. The longest surviving patient with severe sequelae currently is in his 3 4th year.

### 21

The sequelae of submersion are brain injuries. Therefore, one alternatively could
calculate the cost of submersion injuries with the work loss estimates for ages 0

− 4 developed for CDC for traumatic brain injury of different severities (Miller et al., 2009). In 2000 doll ars, the
short

- term earnings losses (which should approximate parental work loss) and percentage of lifetime earnings lost appear in Table 1 4 . Table 1 5 shows equivalent information for household production. Unfortunately our only insight into the traumatic brain injury ( TBI ) severity distribution for submersion injuries is information from key informants Taylor and Riggsbee. That information suggests that 98 percent of the cases might face 100 percent disability (meaning
it is associated with 100 percent lo ss and is not covered in Table s 14

- 15 ; an d 2 percent might be Abbreviated Injury Scale 3 ( A IS 3
, http://www.trauma.org/archive/scores/ais.html ) ( e.g ., a case that resulted in deafness).

Table 14. Short-Term Wage Loss and Percentage of Lifetime Earnings Lost to Traumatic Brain Injury by Abbreviated Injury Scale (AIS) Threat to Life Severity

AIS Admitted ED & Released Outpatient Dept MD Office All

Short

- Term Earnings Loss ( in 2000 dollars )

1

- Minor Injury $ 2,289 $ 1,229 $ 82 $ 112 $ 842 2

- Moderate Injury $ 2,179 $ 468 $ 86 $ 285 $ 686 3

- Serious Injury $ 3,561 $ 1,926 $ 242 $ 2,600 4

- Severe Injury $ 3,000 $ 550 $ 412 $ 2,016 5

- Critical Injury $ 3,613 $ 3,613 Percentage of Lifetime E arnings Lost

1

- Minor Injury 6.811% 0.102% 0.114% 0.041% 1.642% 2

- Moderate Injury 4.683% 0.398% 0.337% 0.399% 1.009% 3

- Serious Injury 5.729% 0.290% 0.102% 3.111% 4

- Severe Injury 5.884% 0.316% 0% 3.647% 5

- Critical Injury 20.646% 20.646%

### 22

Table 15. Short-Term Household Production Loss and Percentage of Lifetime Household Production Lost to Traumatic Brain Injury by Abbreviated Injury Scale (AIS) Threat to Life Severity

AIS Admitted ED & Released Outpatient Dept MD Office A ll

Short

- Term Household Production Lost (in 2000 dollars)

1 $ 732 $ 249 $ 94 $ 96 $ 275 2 $ 678 $ 162 $ 101 $ 137 $ 232 3 $ 1,186 $ 400 $ 113 $ 780 4 $ 1,033 $ 158 $ 49 $ 681 5 $ 1,009 $ 1,009

Percentage of Lifetime Household Production Lost

1 7.081% 0.096% 0.093 % 0.083% 1.725% 2 4.775% 0.445% 0.500% 0.483% 1.068% 3 5.689% 0.373% 0.061% 3.117% 4 6.716% 0.281% 0.024% 4.132% 5 19.238% 19.238%

### 23



# Quality of Life Loss
This section reviews existing evidence on quality of life loss, willingness to award compensation for, and willingness to pay to reduce the risk of CO and lead poisoning and submersion. It relies primarily on existing quality-adjusted life year (QALY) rating scales to quantify quality of life loss. A QALY is a health outcome measure defined such that a year in perfect health is 1, death is 0, and fates worse than death are allowed. Most Americans and Canadians rate a persistent unconscious state as worse than death (see, e.g ., the systematic
review in Miller et al.
, 199 5 ).
One family of QALY rating scales proved especially applicable to the health conditions under study. Versions 1 and 2 of the Health Utility Index (HUI) were designed to assess QALY loss associated with birth-related problems and chronic childhood conditions (Torrance et al. 1982, 1996). Torrance et al. (1982, 1996) surveyed 112 Ontario parents to calibrate HUI-1 and
194 to ca librate HUI-2. HUI-1 estimates 20 percent QALY loss is associated with needing special education due to trouble learning or remembering. QALY loss rises to 48 percent if the

c ondition will make it impossible for the child to work in a normal setting and 81 percent if the

c hild also will need long-term help with self-care (eating, dressing, bathing, toileting).
Torrance et al. (1996) consider HUI

- 2 a refinement of HUI

- 1. It assesses more cognitive
and self

- care states but does not address work

- readiness. Table 1 6 shows HUI

- 2 scores for the range of health states commonly associated with CO poisoning
, lead poisoning
, and submersion.
The mildest retardation causes a 5 percent lifetime QALY loss, with retardation serious enough to require special education associated with a 13 percent loss and severe retardation a 51 percent loss. Because lead poisoning harms reproductive health, it adds a further 2 percent to 3 perc ent
loss. Blood lead levels above 60 μg/dL create habitual irritability , which raises losses by 15
percent to 30 percent . Both CO poisoning and submersion can impair hearing. Depending on degree of hearing loss and severity of retardation, a further 15 per cent to 30 percent loss of lifetime QALYs results. The limitation of these estimates is that frequency data on these health status changes do not exist.
Several studies focus more narrowly on retardation losses. Miller (2004) reviewed QALY loss estimates related to reduced IQ loss and retardation. Table 17 summarizes its estimates. They tend to be higher than the estimates in Table 16, with maximum loss exceeding 80 percent.

### 24

Table 16. Health Utility Index 2 Estimates of Utility Loss for Brain Injury by Functional Impact
Normal self

- care Independent self

care with difficulty Needs help to eat,

bathe, dress, or toilet With No Impact on Mobility, Emotional Health, Pain, or Reproductive Health Learns and remembers more slowly than classmates 5.3% 8.3% 25.4% Requires special education because learns and remembers very slowly 12.7% 15.5% 31.4%
Unable to learn and remember 37.1% 39.2% 50.9%

With Mild Impact on Reproductive Health (any positive lead level) Normal self

- care Inde pendent self

care with difficulty Needs help to eat,

bathe, dress, or toilet Learns and remembers more slowly than classmates 8.3% 11.3% 27.9% Requires special education because learns and remembers very slowly 15.5% 18.2% 33.6%
Unable to learn and reme mber 39.2% 41.2% 52.5%

With Habitual Irritab ility (BLL>=60 μg/dL) + Reproductive Impact Normal self

- care Independent self

care with difficulty Needs help to eat,

bathe, dress, or toilet Learns and remembers more slowly than classmates 37.6% 39.7% 51 .3% Requires special education because learns & remembers very slowly 42.7% 44.6% 55.3%
Unable to learn and remember 59.2% 60.6% 68.6%

With Hear ing Limitations (possible sequelae, submersion or CO poisoning) Normal self

- care Independent self

care w ith difficulty Needs help to eat,

bathe, dress, or toilet Learns and remembers normally 14.8% 17.6% 33.1% Learns and remembers more slowly than classmates 19.4% 22.0% 36.7% Requires special education because learns and remembers very slowly 25.8% 28.2% 41.8%
Unable to learn and remember 46.7% 48.5% 58.6%

With Deaf

ness (possible sequelae, submersion or CO poisoning) Normal self

- care Independent self

care with difficulty Needs help to eat,

bathe, dress, or toilet Learns and remembers normally 41.3% 43.3% 54.3% Learns and remembers more slowly than classmates 44.6% 46.4% 56.9% Requires special education because learns and remembers very slowly 49.1% 50.8% 60.5%
Unable to learn and remember 64.0% 65.2% 72.4% Computed with the Torrance et al. (1996) scoring algorithm.

### 25

Table 17. Utility Loss Associated with Retardation


### Condition % Utility Loss Source Very severely retarded 83 75+ 91 Torrance (1996) Am Med Assoc

. (1984) MacKenzie (1994) Retarded, needing help with care 5 7 54

– 57 55

– 75 77 Kaplan (1976) Torrance (1996) Am Med Assoc

. (1984) MacKenzie (1994) Moderately retarded with self

- care 42

– 51

48

– 51 25

– 50 49 Kaplan (1976) Torrance (1996) Am Med Assoc . (1984) MacKenzie (1994) Mildly retarded 33 20

– 27 23 23 10

– 20 26 Kaplan (1976) Torrance (1996) Sintonen (1994) Glotzer (1995) Am Med Assoc. (1984) MacKenzie (1994) Source: Miller et al. (2004)


### In Global Burden of Disease studies (World Health Organization (WHO) 200 8 ), Dutch EQ

- 5d survey data indicated mild ment al retardation attributable to lead exposure results in a
36.1 percent QALY loss. This estimate is lower than WHO’s earlier 45.9 percent loss estimate for mental retardation, which was based on expert judgment (World Health Organization, 2008)

. It is consi stent with moderate retardation estimates in Table 1 7 but higher than the HUI

- 2
estimates in Table 1 6

. EPA took a jury verdict approach to value the quality of life loss associated with developmental toxicity (Lopez et al. 1995). From 132 jury verdicts for severe birth defects (c erebral palsy with severe mental retardation, quadriplegia, other symptoms that require lifetime custodial care, deafness, and blindness), they estimated willingness to award for a severe birth defect was $8.0 million (inflated to 2010 dollars) with a standard deviation of $7.6 million. That far exceeds other estimates. We also experimented with a jury verdict approach
, u sing jury verdict data that CPSC purchased on near

- drowning (9 cases) and nonfire

- related carbon monoxide poisonin g (92 cases). Unfortunately, virt ually none of the cases state d past or future medical or earnings losses. Without data on these monetary losses, which are included in the compensation paid, it was impossible to develop a regression equation to estimate no n

- monetary

### 26

losses from monetary losses. The data also included minimal information on victim heath status,
with t he large majority of cases merely coded as CO poisoning. Among the cases with diagnostic information, seven were coded as headaches, eight as m ild brain damage
, one as moderate brain damage, one as seizure disorders, one as paraplegia, and one as death. Circumstance data also were quite spotty
, with most cases merely coded as accidents at different locations ( e.g ., rental homes, motels)

.

Torrance et al. (1982 ) also provides a basis for computing QALY loss from work loss for impairments like IQ loss that primarily impact earning capacity. Torrance estimates lost ability to
work causes a 32.66 percent QALY loss

. Applying that estimate in conjunction with the QALY
valuation that CPSC’s ICM uses in its sensitivity analyse s, monetized QALY loss from lost work is 1.43 times associated wage, fringe benefit, and household production losses, implying an incremental quality of life loss of 0.43 times product ivity loss.


# Lead Poisoning

Several studies estimated lifetime loss es from lead poisoning directly. Agee and Crocker (1996) examined household decisions about obtaining chelation therapy for 256 lead-exposed children (with much higher exposures than currently are typical). They estimated willingness to pay (WTP) was $24 for a 1 percent reduction in a child’s lead burden, with a range from $16 for
house holds that decided against chelation therapy to $155 for ones that chose it. WTP was 3.1 times medical plus work losses a weighted average of ratios of 20.0 for those choosing chelation and 2.1 for those choosing against it. Perhaps because they are for high lead exposures, all three ratios (3.1, 20.0, and 2.1) exceed the all

- cause ratio of 1.43 from Torrance e t al. (198 2 ). Lutter (2000) claimed to convert Agee and Crocker’s estimates into WTP of $1
, 100 to $1
, 900 per IQ point gained; his estimate that WTP is about 1/6 of the wage loss is inconsistent with Agee and
Crocker’s underlying estimate and with Torrance’ s estimate.
At current exposure levels, Muennig (2009), using 2000 −2002 MEPS EQ5d data,

e stimated lifetime QALY loss per lead-exposed child averages 20 percent (computed at a 3 percent discount rate, with standard deviation of 8 percent). That estimate is slightly above Table
1 6 estimates, close to moderate retardation e stimates in Table 1 7 , and below the Dutch EQ5d

### 27

estimate of 36 percent. We consider it the best estimate for lead poisoning, with sensitivity

a nalysis recommended at 15 percent and 35 percent loss.


# CO Poisoning
Without a CO alarm in a home, CO poisoning often continues for some time before it is
de tected. Table 18 shows the signs and symptoms that may accumulate prior to detection. Treatment with oxygen, either normobaric (face mask) or hyperbaric (high-pressure chamber) clears many of these symptoms, at least initially. Neurologic symptoms, however, often persist or develop days to weeks after apparent recovery. UHMS data indicate that 17.7 percent of those

tre ated with hyperbaric oxygen who were tested (15.1 percent of all hyperbaric patients) had

c ardiac abnormalities consistent with cardiac injury.
A randomized trial of hyperbaric oxygen treatment gives probabilities of longer term

se quelae among 224 patients treated in emergency departments or admitted (Weaver et al. 2007, Weaver 2009). Initial carboxyhemoglobin levels in this population averaged 22 percent with a
standa rd deviation of 11 percent. Those levels are greatly influenced by how long the victim was removed from the CO exposure and how long they received normobaric oxygen en route/at the treating facility. Hampson et al. (2012 ) reported initial levels for 1
, 394 hyperbaric patients averaged 23.4 percent with a standard deviation of 10.4 percent and a range from 0.1

- 77.0
percent . T he ir samples were obtained an average of 2.2 hours from the end of t he CO exposure ( s tandard deviation 6.9 hours, range 0 to 198 hours).

Table 18. Acute Symptoms in 1144 Patients with Carbon Monoxide Poisoning Symptom % of Patients Headache 85% Dizziness 69% Fatigue or generalized weakness 67% N ausea or vomiting 52% Trouble thinking or confusion 37% Loss of consciousness 35% Dyspnea 7% Chest pain 2% Source: Lavonas, 2007, pooled data from 7 studies.



### Table 1 9 shows the probability of neurocognitive sequelae over time
, with and without hyperba ric oxygen. Without hyperbaric oxygen, 34 percent of patients reported headaches at four

### 28

weeks (Weaver 2009). In a follow-up study, six years after poisoning, 37 percent (17/42) had abnormal neurologic evaluations, and 19 percent (10/52) had cognitive prob lems, with some unstated overlap (Weaver 2009). Of 17 patients with neurologic abnormalities, 88 percent had cerebellar, 29 percent cranial, 29 percent motor, 18 percent deep tendon reflex, and 12 sensory abnormalities (Weaver et al. 2008). Of 10 patients with cognitive deficits, all had deficits in visual memory, 80 percent in attention, 70 percent in verbal memory, and 70 percent in executive
function in the Hopkins and Weaver abstracts for which no paper has been published (Hopkins & Weaver 2008). None h ad slow mental processing speed.

Table 19. Probability of Neurocognitive Sequelae of Carbon Monoxide Poisoning by Treatment Mode and Time Post-Exposure No Oxygen Normobaric

Oxygen Hyperbaric

Oxygen Sequelae at 6 weeks 53% (9/17) 41% (60/146) 24% (18/75) At 6 Months 30% (44/146) 17% (10/58) At 12 Months 18% (27/149 14% (9/62)
Source: Weaver et al., 2007 The source did not differentiate sequelae at 6

- 12 months between no oxygen and normobaric oxygen. 

### Delayed sequelae were common. Among 75 patients with neurocognitive sequelae who participated in early repeat testing, 68 percent had persistent losses over the first six weeks ; 12
percent experienced declines from function immediately post

- treatment during weeks 1

− 2 ; and
another 20 percent e xperienced declines during weeks 3

− 6. Only 6 of 17 patients with
abnormalities after six years had cognitive sequelae at six weeks and only seven did at 12 months (Hopkins & Weaver 2008). The Hopkins and Weaver abstracts seemed to suggest some of the symptom increase was unrelated to the CO poisoning
, but it was unclear how much.
Procedure codes in HCUP were too coarse to provide rates of hyperbaric oxygen use versus oxygen administration by face mask. The 1,500 hyperbaric chamber cases in 2002, and
the 14,236 medically treated cases in 2006, suggest that perhaps 10 percent to 12 percent receive
h yperbaric treatment. In the nonrandomized portion of Weaver’s three

- state study , 37 percent of those without hyperbaric oxygen received no oxygen ( Weaver , 2009 ) ( All hyperbaric oxygen was randomly assigned, so the study provided no insight into its usage frequency.) Applying that ratio suggests 26 percent to 27 percent of CO patients get no oxygen therapy. Sequelae rates would average 43 percent at six weeks, 29 percent at six months, 17 percent at 12 months , and
19 percent to 37 percent at six years

. Severity of c ognitive sequelae was quite large
, an average

### 29

score three standard deviations below the population norm on a batt ery of seven

n europsychological tests: g eneral orientation, digit span, Trail Making (Parts A and B) , digit

symbol , block design , and story recall (Weaver et al. 2007). Unfortunately, we could not translate that severity into HUI

- 2 categories. Based on the estimates in Table 16, we conservatively suggest assuming a 15 percent QALY loss for those with sequelae, with sensitivity analysis at 20 percent and 35 percent

. With the $5 million value of statist i cal life that CPSC uses, lifetime QALYs are valued at $4,062,185 ($5,0 00,000 to $937,815 in productivity losses from above), so a 15 percent loss would be valued at $609,328.



# Submersion
No data on submersion severity was available because HCUP procedure codes lacked sufficient detail to identify intubation or ICU usage. We suggest assuming that 90 percent of admitted cases will be tracheotomy-tube dependent with utility losses in the 90 percent range,
with t he rest experiencing losses of perhaps 20 percent to 25 percent. We assume non-admitted

c ases would suffer no sequelae.



# Future Research

For submersions and CO poisoning, if Medicaid claims data were available, we would

use discharge to inpatient rehabilitation or long-term care, intensive care unit u se , a nd intubation procedure codes to infer the frequency of severe sequela e. Receipt of services like physical and speech therapy could be used to infer the frequ ency of more moderate sequelae.

### 30 

# Summary
In summary, this report provides incidence data and a wide range of data on costs per case for CO and lead poisoning and submersion, by exposure severity. Those data will improve ICM estimates for these severe health challenges.

Unfortunately, severity distribution data are unavailable, so we can only provide average figures by assuming a distribution. The easiest and least burdensome way to get accurate severity distributions for CO poisoning and submersion is to analyze Medicaid or possibly private health insurance claims files. In the interim, our best estimates are:

 For CO poisoning, quality-adjusted life-year (QALY) loss and lifetime earnings loss are perhaps 15 percent per year with sequelae, with at least 20 percent of patients experiencing lifetime sequelae. That implies a 3 percent lifetime loss.

 For lead poisoning, a 20 percent QALY loss is the average for child exposures, with
loss es rising with blood lead level. Lead poisoning also results in ADHD and crime that are costly and further reduce quality of life.

 For submersion, perhaps 90 percent of hospital inpatients experience a 90 percent QALY
loss
, with the remainder experiencing losses of 20 percent to 25 percent, yielding a combined average of 83 percent. Treated and released cases probably experience minimal QALY loss.

### 31 

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CDC. Fourth n ational report on human exposure to environmental chemicals, updated t ables, February 2012. Atlanta, GA: Centers for Disease Control and Prevention. http://www.cdc.gov/exposurereport/, 2012. Chambers JG, Shkolnik J, Pérez M. Total Expenditures for Students with Disabilities, 1999 -2000: Spending Variation by Disability. Report 5, Special Education Expenditure Project, Washington DC: American Institutes for Research, 2003. Chandramouli K, Steer CD, Ellis M, Emond AM. Effects of early childhood lead exposure on academic performance and behaviour of school age children. Archives of Disease in Childhood, 94:11, 844-848, 2009. Chen A, Cai B, Dietrich KN, Radcliffe J, Rogan WJ. Lead exposure, IQ, and behavior in urban 5- to 7-year-olds: Does lead affect behavior only by lowering IQ? Pediatrics, 119,

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### 34

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### 35

Weaver LK. Carbon monoxide poisoning. New England Journal of Medicine, 360: 12, 1217 −1225, 2009.
W orld Health Organization. The global burden of disease, 2004 update. Geneva: WHO, http://www.who.int/healthinfo/global Wright JP, Dietrich KN, Ris MD, Hornung RW, Wessel SD, Lanphear BP, Ho M, Rae MN. Association of prenatal and childhood blood lead concentrations with criminal arrests in early adulthood. PLOS Medicine, 5:5, e101, 732−740, 2008. Zaloshnja, E., Miller, T., Jones, P., Litovitz, T., Coben, J., Steiner, C., & Sheppard, M. (2008). The impact of poison control centers on poisoning-related visits to emergency departments, U.S., American Journal of Emergency Medicine, 26:3, 310−315. Zamula W. Social costs of drownings and near-drownings from submersion accidents occurring to children under 5 in residential swimming pools, Bethesda MD: Directorate for Economic Analysis, 1987.

### 36



# Appendix A: Other Costs of Lead Poisoning

Special Education . EPA analyzed the costs of special education for children with leadinduced IQ deficits (Agarwal, 1998). We used their estimates of the frequency of special education usage and updated associated costs with current data from the U.S. Department of Education. “The number of children with IQ less than 70 and the number of children with blood lead levels above 20 μg/dL can be used to measure cognitive effects seen mostly in children with high levels of lead exposure. An IQ score of 70 is two standard deviations below the population mean; it is used as an indicator of mental retardation and as the cut-off for special education requirements. Blood lead levels above 20 μg/dL are the level at which CDC traditionally
recommend ed

complete medical evaluation, environmental assessment, and necessary
environmental remediation for the child and his/her environment. EP A (Agarwal, 1998) used
NHANES III data to indi cate the fraction of one to two

- year olds falling within these categories.
An estimate d 0.115 % of children with lead poisoning have IQs under 70 as a result , and 0.588 % have blood lead levels above 20 μg/dL.” ( Agarwal, 1998). These data suggest that 19.6% (.115/.588) of children with lead levels exceeding 20 μg/dL require special education.
Exclusive of capital spending and debt service, average spending per pupil in U.S. public elementary or secondary school was $10,441 in FY 2007−2008 (National Center for Education
S tatistics, 2011, Table 190, in Feb 2009 dollars). 2 

### Based on a massive national study, Chambers et al. (2003) reports that spending per special education student is 1.6 times spending on other students. Swanson (2008) reports that 9 percent of U

. S. students have special educational needs. Thus the additional spending per US special needs student is $5,944 (0.6 * $10,441 / (.91 + .09 * 1.6)). The special education multipliers average (a) 2.3 for mental retardation (or for orthopedic impairment) and (b) 2.5 for traumatic brain injury (Chambers et al. 2003, Exhibit 1), implying

a nnual special education costs of (a) $22,784 and (b) $24,765 for these conditions. Thus special

e ducation spending per lead poisoning case at ages 0-4 averages $4,660 per school year or $46,713 in present value from grades K−12 (assuming exposure at age 2).

2 This estimate excludes $1,676 per pupil in annual capital spending and debt service. Those costs would not be higher for special education students.

### 37

ADHD . Braun et al. (2006) analyzed data from the National Health and Nutrition Examination Survey (NHANES-III) and found that children with blood lead concentrations

g reater than 2 μg/dl were at a 4.1-fold increased risk of ADHD. Medical costs of ADHD average $1
, 586 per year (or $14,984 from ages 6 through 18, brought to present value using a 3 percent
discount ra te; inflated to 2009 dollars) (Swensen et al., 2003). This estimate is based on cost
diff erentials relative to a matched control group in a privately insured population. The present value of QALY losses through age 18 for ADHD diagnosed at age 6 averages 1.9. Secnik et al. (2005) estimated the mean QALY level for a child with an acute case of ADHD at 0.74. They rated the utility of someone with chronic ADHD treated with no side effects at 0.96 compared to unmedicated utility of 0.88, implying an annual utility loss of at least 0.08 and possibly as much
as 0.12 from chronic ADHD. These estimates were based on children in the United Kingdom assessed using the EQ5d QALY instrument . Data were not readily availab le on the QALY norm for the age group studied . No comparable Unit ed States data were available. Coghill et al. (2004) estimated utility of an ADHD responder to treatment at 0.837 (standard error 0.039) and of a

non

- responder to treatment at 0.773 (standard error 0.039), independent of treatment received
, suggesting a lo ss of at least 0.064 (0.837

– 0.773)

.
Crim e

. Wright et al. (2008) finds that child lead poisoning increases criminal behavior. “Adjusted total arrest rates ” for violent and non

- violent crime “ at ages 18

− 24 were greater for
each 5 μ g/dl increase in blood lead concentration: ” Relative risk ( RR ) “ = 1.07 (95% CI 0.88

– 1.29) for average childhood blood lead through age 6, and 1.27 (95% CI 1.03

– 1.57) for blood lead at age 6. Adjusted arrest rates for violent crimes at ages 18

− 24 were greater for each 5 μ g/dl
increa se in blood lead: RR = 1.30 (95% CI 1.03

– 1.64) for average childhood blood lead, and 1.48 (95% CI 1.15

– 1.89) for blood lead at age 6.” We assume these odds rati os apply to both youth and subsequent adult crime, and that the differential arrest rate s match the differential
crime rate s

. If lead poisoning is relatively rare, with RR=1.27, per 5 μ g/dl, crime associated with lead poisoning will equal roughly 0.27 times the average crime rate. With crime incidence from Miller and Hendrie (2013) , RR for non

- violen t crime would be 1.2 3 (0.27 * 98,827,502 crimes

- 0.48 * 20,380,407 violent crimes ) / 78,447,095 non

- violent crimes ) for each 5 μ g/dl increase in
blood lead

.

### 38

Using these RR s requires separate costs for violent and non-violent personal crimes covered in arrest data. We relied on estimates from Miller and Hendrie (2013), but substituted the $5 million value of a statistical life that CPSC uses in its regulatory analyses.
Table 20 summarizes unit costs by crime used to estimate costs per crime. Table 21

pr esent s incidence, percentage of crimes reported to police, and percentage leading to arrest. Costs per police-reported crime averaged $ 49,727 for violent crime and $3,328 for property crime. Costs per crime we re lower at ages 8−18 than at ages 18 and older.
Tab le 2 2 shows the age distribution of arrestees and associated crimes per person under the assumption that virtually all arrests at ages 0−14 occur at ages 8−14. Applying the rise in

re lative risk from above to the crime rate per capita, then multiplying times cost per crime yields
the a nnual crime costs per 5 μg/dl rise in blood lead level by age shown in the right-hand columns. We computed present value of these annual costs over a lifespan starting at age 2, accounting for life table probabilities of survival from year to year. Conservatively, except in sensitivity analysis, we restricted Table 2 2 to police-reported crimes and excluded impaired driving crashes, intimate partner violence, and child maltreatment. Present value of estimated costs per 5 μg/dl rise in blood lead level are $77,125, including $74,898 in violent crime costs and $2,228 in non-violent crime costs. Had we assumed crimes not reported to the police are reduced proportionately to police-reported crimes and included all personal crimes, estimated

c rime costs per 5 μg/dl rise in blood lead level would be $181,824 , including $ 176,516 in violent

c rime costs and $5,308 in non-violent crime costs. Blood lead level elevation from consumer products depends on method and duration of exposure. Licking a toy regularly, swallowing something, or licking a product on a single access are quite different exposures. To estimate resulting blood lead levels, a regulatory analysis presumably would draw on medical or engineering expertise or on historical da t a on elevation with similar exposures.

### 39

Table 20. Costs per Police-Reported Crime by Cost Category in 2010 Dollars

Medical Mental

Health Work Property Damage Public

Services* Quality of

Life Adjudication &

Sanctioning Perpetrator

Wor k Loss Total

Murder $16,183 $10,735 $1,577,758 $175 $2,852 $3,422,242 $368,336 $143,023 $5,541,304 Rape $2,887 $5,830 $5,765 $157 $790 $128,196 $24,679 $9,517 $177,821 Robbery $1,313 $176 $2,716 $1,143 $405 $14,754 $11,866 $4,413 $36,786 Assault $1,141 $361 $1,879 $70 $335 $12,708 $5,655 $1,878 $24,027 Burglary $0 $0 $34 $2,564 $450 $0 $2,041 $693 $5,782 Larceny/Theft $0 $0 $27 $936 $442 $0 $778 $168 $2,351 Motor Vehicle Theft $0 $0 $102 $6,423 $269 $0 $1,778 $571 $9,143 Arson $2,373 $40 $2,924 $17, 411 $3,561 $5,548 $2,310 $603 $34,770 Forgery/Counterfeiting $0 $0 $0 $414 $266 $0 $2,525 $682 $3,887 Person

- to

- Person Fraud $0 $0 $0 $1,687 $65 $0 $2,289 $682 $4,723 Embezzlement $0 $0 $0 $414 $266 $0 $2,743 $682 $4,105 Buying Stolen Property, $0 $0 $0 $0 $266 $0 $4,791 $1,169 $6,226 Vandalism $0 $0 $88 $261 $70 $0 $2,075 $724 $3,218 Weapons Carrying, $0 $0 $0 $0 $70 $0 $2,289 $799 $3,158 Prostitution/Pandering $0 $0 $0 $0 $70 $0 $229 $80 $379 Other Sex Offenses $1,278 $3,682 $3,947 $145 $316 $86, 102 $24,679 $9,517 $129,666 Drug Possession/Sales $0 $0 $0 $0 $4,490 $0 $3,202 $1,118 $8,810 Gambling $0 $0 $0 $0 $70 $0 $229 $80 $379 DUI, No Crash $0 $0 $0 $0 $19 $0 $415 $145 $579 Liquor Law Violations $0 $0 $0 $0 $70 $0 $1,093 $381 $1,544 Drunkenn ess $0 $0 $0 $0 $70 $0 $1,093 $381 $1,544 Disorderly Conduct $0 $0 $0 $0 $70 $0 $1,093 $381 $1,544 Vagrancy $0 $0 $0 $0 $70 $0 $1,093 $381 $1,544 Curfew/Loitering Violations $0 $0 $0 $0 $70 $0 $1,093 $381 $1,544 All Other Nontraffic Offenses $0 $0 $0 $0 $70 $0 $229 $92 $391 All Violent Crime $1,254 $619 $7,016 $377 $396 $28,681 $8,410 $2,974 $49,727 All Other Personal Crime $0 $0 $27 $856 $622 $0 $1,386 $436 $3,328 Perpetrator Ages 8−17 Years All Violent Crime $1,202 $475 $3,358 $452 $ 403 $18,215 $6,855 $2,359 $33,320 All Other Personal Crime $0 $0 $39 $969 $489 $0 $1,425 $449 $3,371 Perpetrator Ages 18 & Over All Violent Crime $1,280 $691 $8,835 $340 $392 $33,885 $9,183 $3,280 $57,885 All Other Personal Crime $0 $0 $24 $831 $652 $0 $1,405 $444 $3,356 * Public services include police, fire, EMS, victim services. Violent crimes are rape, robbery, assault, arson, other sexual offenses, intimate partner violence, and child maltreatment.

### 40

Table 21. Percentage of Crimes Reported, Percentage of Reported Crimes that Lead to an Arrest, and Number of Arrests in 2010 Reported Crimes %

Reported % Arrested

of Reported % Under

Age 18 Arrests

Murder 16,259 100.0% 73.9% 9.0% 11,201 Rape 92,322 9.8% 21.8% 14.1% 20,088 Robbery 409,584 65.6% 27.4% 24.1% 112,300 Assault 4,414,537 43.8% 38.1% 15.4% 1,700,937 Burglary 2,385,971 50.7% 12.1% 22.7% 289,769 Larceny/Theft 8,460,936 31.0% 15.0% 22.3% 1,271,410 Motor Vehicle Theft 761,669 85.4% 9.4% 22.1% 71,487 Arson 65,763 100.0% 20.4% 48.5% 13,416 Forgery/Counterfeiting 293,828 31.0% 26.6% 2.2% 78,101 Fraud 1,166,474 31.0% 16.1% 3.2% 187,887 Embezzlement 46,681 31.0% 35.6% 2.7% 16,616 Buying Stolen Property, 157,806 100.0% 60.1% 15.6% 94,802 Vandalism 3, 594,637 8.3% 7.0% 30.6% 252,753 Weapons Carrying, 322,300 100.0% 49.3% 19.8% 159,020 Prostitution 66,926 100.0% 93.6% 1.7% 62,668 Other Sex Offenses 232,953 9.8% 31.2% 18.0% 72,628 Drug Possession/Sales 2,242,480 100.0% 73.1% 10.4% 1,638,846 Gambling 11,458 100.0% 86.8% 13.8% 9,941 Intimate Partner Violence 628,331 3.7% 100.0% 3.5% 111,062 Child Maltreatment 512,790 22.9% 100.0% 6.0% 689,435 Driving Under the Influence 560,718 31.2% 100.0% 0.9% 1,412,223 Liquor laws 615,172 100.0% 100.0% 18.9% 51 2,790 Drunkenness 32,033 100.0% 100.0% 2.3% 560,718 Disorderly conduct 94,797 100.0% 100.0% 25.1% 615,172 Vagrancy 3,720,402 100.0% 100.0% 6.8% 32,033 Curfew/Loitering Violations 5,231,417 100.0% 100.0% 100.0% 94,797 All Other Non

- Traffic Offenses 25,675,409 100.0% 100.0% 8.0% 3,720,402 All Violent Crimes 16,259 27.9% 48.5% 14.8% 2,731,067 All Non

- Violent Crimes 92,322 33.8% 25.0% 12.2% 512,790

### 41

Table 22. Annual Arrest Rate and Estimated Crimes Committed per Person by Age Range, 2010, and Estimated Annual Violent and Property Crime Costs Over Different Age Ranges per 5 μg/dl Rise in Blood Lead Level at Age 0

− 4 (in 2010 dollars)

Age Group %

Arrested Police

Reported Crimes per Person Police

- Reported Only; No

DWI, Domestic Violence All Crime

Violent Crime Cost Property

Crime Cost Violent

Crime Cost Property

Crime Cost 8 to 14 years 1.14% 0.045 $1,041 $31 $1 ,919 $41 15 to 19 years 8.68% 0.342 $7,918 $235 $14,600 $313 20 to 24 years 9.45% 0.218 $5,640 $168 $15,276 $521 25 to 29 years 7.18% 0.166 $4,285 $128 $11,605 $396 30 to 34 years 5.57% 0.129 $3,324 $99 $9,004 $307 35 to 39 years 4.33% 0.100 $2,582 $7 7 $6,995 $239 40 to 44 years 3.79% 0.087 $2,261 $67 $6,124 $209 45 to 49 years 3.16% 0.073 $1,887 $56 $5,112 $174 50 to 54 years 2.15% 0.050 $1,285 $38 $3,482 $119 55 to 59 years 1.23% 0.028 $732 $22 $1,983 $68 60 to 64 years 0.64% 0.015 $382 $11 $1,0 34 $35 65 years & over 0.19% 0.004 $111 $3 $302 $10 Arrest rates from Table 4.4, Sourcebook of Criminal Justice Statistics 2010. Washington DC: Bureau of Justice Statistics, 2012.

### 42



# Appendix B: Narrative Descriptors for International Classification of Disease Codes and

NEISS Codes Included

Codes from the 9 th 

### Edition of ICD, Clinical Modification, http://www.cdc.gov/nchs/icd/icd9cm.htm

984 Toxic effects of lead and its compounds (including fumes) 986 Toxic effect of carbon monoxide 994.1 Drowning and nonfatal submersion
E830 Accident to watercraft causing submersion E832 Other accidental submersion or drowning in water transport accident E861.5 Accidental poisoning by lead paints E866.0 Accidental poisoning by lead and its compounds and fumes

E 868 Accidental poisoning by other utility gas and other carbon monoxide E868.0 Liquefied petroleum gas distributed in mobile containers

Butane or carbon monoxide from incomplete combustion of these gases Liquefied hydrocarbon gas NOS or carbon monoxide from incomplete

c ombustion of these gases Propane or carbon monoxide from incomplete combustion of these gases E868.1 Other and unspecified utility gas Acetylene or carbon monoxide from incomplete combustion of these gases

Gas NOS used for lighting, heating, or cooking or carbon monoxide from incomplete combustion of these gases Water gas or carbon monoxide from incomplete combustion of these gases E868.2 Accidental poisoning by motor vehicle exhaust gas E868.3 Accidental poisoning by carbon monoxide from incomplete combustion of othe r

domestic fuels E868.8 Accidental poisoning by carbon monoxide from other sources E868.9 Accidental poisoning by unspecified carbon monoxide

E910 Accidental drowning and submersion

Codes from the 10 th 

### Edition of ICD, h ttp://apps.who.int/classifications/icd10/browse/2010/en (regardless of medical treatment,

m ultiple cause of death data typically include both a diagnosis code and an external cause code)
Diagnosis Codes T56.0 Toxic effect of lead and its compounds T58 Toxic effect of carbon monoxide

### 43

External Cause Codes W 16 Diving or jumping into water causing injury other than drowning or submersion W 29 Contact with other powered hand tools and household machinery (washing

mach ines) W65 Drowning and submersion while in bath-tub W 66 Drowning and submersion following fall into bath-tub W 67 Drowning and submersion while in swimming-pool W 68 Drowning and submersion following fall into swimming-pool W 73 Other specified drowning and submersion W74 Unspecified drowning and submersion X47 Accidental poisoning by and exposure to other gases and vapors Y17 Poisoning by and exposure to other gases and vapors, undetermined intent Y21 Drowning and submersion, undetermined intent

NEISS Codes 64 Submersion (including drowning)