Propiconazole Summary of Analytical Chemistry and Residue Data DP# 372878

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UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

 OFFICE OF 

CHEMICAL SAFETY AND 

POLLUTION PREVENTION 

MEMORANDUM

Date: 11/03/10 

Subject: Propiconazole. Summary of Analytical Chemistry and Residue Data. Amend 

Established Tolerance for Mint. Establishment of Tolerances for Onion 

Subgroups 3-07 A and B and the Berry Subgroups 13-07 A, B, and G. 

PC Code: 122101 DP Barcode: D372878 

Decision No.: 425825 Registration No.: 100-617 

Petition No.: 9E7659 Regulatory Action: Section 3 

Risk Assessment Type: Chemistry Case No.: NA 

TXR No.: NA CAS No.: 60207-90-1 

MRID No. 47929501 40 CFR: 180.434 

Reviewer: Jerry B. Stokes, Chemist 

Risk Assessment Branch 4 

Health Effects Division (7509P) 

Through: Susan Hummel, Senior Chemist 

Risk Assessment Branch 4 

Health Effects Division (7509P) 

To: Rebecca Daiss, Biologist 

Risk Assessment Branch 4 

Health Effects Division (7509P) 

Barbara Madden, Risk Manager 

 Emergency Response Branch 

 Registration Division (RD, 7505P) 

 

Executive Summary 

Propiconazole is a triazole-type fungicide (Group 3) that provides broad spectrum disease control 

on a variety of crops. Tolerances in/on plant and animal commodities are currently established 

for the combined residues of propiconazole, 1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-

yl]methyl]-1H-1,2,4-triazole, and its metabolites determined as 2,4-dichlorobenzoic acid (2,4-
Propiconazole Summary of Analytical Chemistry and Residue Data DP# 372878

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DCBA) and expressed as parent [40 CFR §180.434]. Tolerances on plant commodities range 

from 0.1 ppm to 40 ppm in/on grass straw, and tolerances on animal commodities range from 

0.05 ppm in milk to 2.0 ppm in liver and kidney of livestock. 

Syngenta Crop Protection (Syngenta) and Interregional Research Project No. 4 (IR-4) have 

submitted a petition supporting amended tolerances for uses on various crops for propiconazole, 

formulated as a 3.6 lb/gal emulsifiable concentrate (EC). Tolerances for peppermint and 

spearmint tops are to be increased from 3.5 to 10.0 ppm. Existing tolerances for berry group 13 

(1.0 ppm), onion, bulb (0.2 ppm), onion, green (9.0 ppm), and strawberry (1.3 ppm) are to 

removed and the same tolerances to be reestablished under new crop groupings: onion, bulb 

subgroup 3-07A (0.2 ppm), onion, green subgroup 3-07B (9.0 ppm), caneberry subgroup 13-

07A (1.0 ppm), bushberry subgroup 13-07B (1.0 ppm), and low growing berry subgroup 13-07G 

(except cranberry) (1.3 ppm). 

The nature of propiconazole residues in plants and animals is adequately understood based on the 

available peanut, wheat, grape, rice, celery, carrot, goat, and poultry metabolism studies. A 

major metabolic pathway in plants appears to be hydroxylation (primarily of the beta-carbon) of 

the n-propyl group on the dioxolane ring of the cis/trans isomers of propiconazole. These 

metabolites appear to readily form sugar conjugates. HED concluded that for plants and animals, 

residues of propiconazole and all its metabolites containing the 2,4-dichlorophenyl moiety (2,4-

DCBA), including conjugates, are of concern risk assessments. For tolerance expression, HED 

concluded that the current tolerance expression for propiconazole should include residues of 

propiconazole per se only. This allows for harmonization with the residue definition for Codex. 

A GC method using flame ionization detection (Method AG-354) is available for determining 

residues of propiconazole per se in/on plant commodities, and has an LOQ of 0.05 ppm. In 

addition, Multiresidue Methods Section 302 can also be used to determine parent propiconazole 

in both plant and animal matrices. The validated LOQ for combined residues was 0.05 ppm in 

all raw and processed commodities. Each of the methods was validated in conjunction with the 

field trials and processing studies. 

The available field trial data are adequate and support the proposed use patterns for 

propiconazole (EC) on mint and other crops listed above. The number and geographic 

distribution of the field trials are adequate, and the appropriate samples were collected. Samples 

were analyzed using adequate analytical methods and the sample storage intervals are supported 

by the available storage stability data. Adequate storage stability data are available indicating 

that residues of propiconazole are stable at ≤-15 C from 4-39 months in a variety of 

commodities. 

There are no feedstuffs associated with the proposed uses in this petition. Therefore, livestock 

dietary burdens are not addressed. 

Adequate confined rotational crop studies are available indicating that the residues in rotational 

crops are similar to the primary crops. The confined studies also support the 105-day plant-back 

interval (PBI) currently listed on product labels for crops without direct uses. Currently, 

propiconazole tolerances for inadvertent residues in/on alfalfa forage and hay at 0.1 ppm. 
Propiconazole Summary of Analytical Chemistry and Residue Data DP# 372878

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Residue Chemistry Deficiencies 

Interregional Research Project No. 4 (IR-4) have submitted a petition supporting amended 

tolerances for uses on various crops for propiconazole, formulated as a 3.6 lb/gal emulsifiable 

concentrate (EC). Tolerances for peppermint and spearmint tops are to be increased from 3.5 to 

10.0 ppm. Existing tolerances for berry group 13 (1.0 ppm), onion, bulb (0.2 ppm), onion, green 

(9.0 ppm), and strawberry (1.3 ppm) are to removed and the same tolerances to be reestablished 

under new crop groupings: onion, bulb subgroup 3-07A (0.2 ppm), onion, green subgroup 3-

07B (9.0 ppm), caneberry subgroup 13-07A (1.0 ppm), bushberry subgroup 13-07B (1.0 ppm), 

and low growing berry subgroup 13-07G (except cranberry) (1.3 ppm). 

Conclusion: No major deficiencies were noted in the subject petition that would preclude 

establishing the proposed changes for propiconazole as listed above. 

 

Background 

Propiconazole is a triazole-type fungicide (Group 3) that provides broad spectrum disease control 

through inhibition of sterol biosynthesis in fungi. It is registered to Syngenta Crop Protection for 

the control of fungal diseases on a variety of crops. It is formulated as 3.6 lb/gal emulsifiable 

concentrates (EC) under the trade name Tilt®. Other propiconazole end-use products are 

marketed in the United States under a variety of trade names. However, the 3.6 lb/gal EC 

product used in this petition will be discussed. 

Permanent tolerances are currently established for the combined residues of propiconazole, 1-

[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole, and its 

metabolites determined as 2,4-DCBA and expressed in parent equivalents, at levels ranging from 

0.1 ppm on numerous plant commodities to 40 ppm in/on grass straw [40 CFR §180.434(a)]. 

Permanent tolerances are also established for the combined residues of propiconazole and its 

metabolites determined as 2,4-DCBA at 0.1 ppm in fat, meat, and meat byproducts (except liver 

and kidney) of livestock, 2.0 ppm in liver and kidney of livestock, and at 0.05 ppm in milk; 

however, no tolerances have been established for eggs and poultry commodities. Time-limited 

tolerances are established for combined propiconazole residues in/on a variety of plant 

commodities at level of 2.0 ppm in/on nectarine and peach [40 CFR §180.434(b)]. In addition, 

tolerances with regional restrictions have been established for combined propiconazole residues 

at 1.0 ppm in/on cranberry and at 0.5 in/on wild rice grain[40 CFR §180.434(c)]. Tolerances 

with inadvertent residues have been established for combined propiconazole residues at 0.1 ppm 

in/on alfalfa forage and alfalfa hay. 
Propiconazole Summary of Analytical Chemistry and Residue Data DP# 372878

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Table 1. Nomenclature of Propiconazole

Compound 

N

N N

O

O

Cl

Cl

Common name Propiconazole 

Company experimental names CGA-64250 

IUPAC name 1-[2-(2,4_dichlorophenyl)-4-propyl-1,3-dioxolan-2-ylmethyl]-1H-1,2,4_triazole 

CAS name 1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole 

CAS # 60207-90-1 

End-use products/EP 3.6 lb/gal EC (EPA Reg. Nos. 100-617 

Table 2. Physicochemical Properties of Technical Grade Propiconazole.

Parameter Value Reference

Boiling point 120 C at 1.9 Pa, >250 C at 101.325 kPa MRID No. 43698701 

pH 4.9 at 25 C (1% aqueous dispersion) MRID No. 43698701 

Density 1.289 g/cm3 at 20 C MRID No. 43698701 

Water solubility 0.10 g/L at 20 C MRID No. 41720301 

Solvent solubility (temperature not specified) 

Completely miscible in ethanol, acetone, 

toluene and n-octanol. hexane = 47 g/L MRID No. 42030201 

Vapor pressure 4.2 x 10-7 mm Hg at 25 C MRID No. 41720301 

Dissociation constant (pKa) 1.09 MRID No. 43698701 

Octanol/water partition coefficient Log(KOW) 3.72 at pH 6.6 and 25 C MRID No. 43698701 

UV/visible absorption spectrum (8max, nm) Not available MRID No. 40583703 

860.1200 Directions for use 

One current end-use product (EP) containing propiconazole that is registered for use on 

feed/food crops is marketed under the trade names Tilt® Fungicide: 3.6 lb a.i./gal (EPA Reg. No. 

100-617). Proposed use directions for these labels are summarized below in Table 3. 

Table 3. Summary of Directions for Proposed Use of Propiconazole on Mint 

Application Timing, Type and 

Equipment 

Formulation 

[EPA Reg. 

No.] 

Single 

rate 

(lb ai/A)

Max. # of 

Apps. per 

Season 

Max. Seasonal 

Rate (lb ai/A) 

PHI 

(days) Use Directions and Limitations 

Peppermint and Spearmint

Broadcast foliar applications 

beginning when plants are 2-4 

inches in height. Apply with 

aerial or ground equipment 

3.6 lb/gal EC 

[100-617] 

0.113 0.338 7 Apply in a minimum of 20 gal/A 

Minimum RTI is 14 days 
Propiconazole Summary of Analytical Chemistry and Residue Data DP# 372878

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860.1300 Nature of the Residue – Plants. 

The nature of propiconazole residues in plants is adequately understood (DP D329394, Y. 

Donovan, 6/15/06). These data indicate that the major metabolic pathway in plants appears to 

involve hydroxylation of the n-propyl group on the dioxolane ring of the cis/trans isomers of 

propiconazole, with subsequent conjugation to sugars. A possible alternative pathway involves 

reductive deketalization of the dioxolane ring and sugar conjugation of the resulting metabolite. 

The alkyl bridge between the phenyl and triazole rings is metabolized and free 1H-1,2,4-triazole 

is released. The free triazole is readily conjugated with the amino acid, serine/alanine, forming 

triazole aniline which is further metabolized to triazole acetic acid possibly through the 

intermediate formation of triazole lactic acid. HED considers free triazole, triazole alanine, and 

triazole acetic acid to be residues of concern in plants. Since these are common metabolites from 

several triazole containing pesticides, the risk assessment for triazoles has been assessed 

separately (HED memo of 2/7/06, M. Doherty, D322215). 

HED has concluded that the residues of concern should include propiconazole and all its 

metabolites containing the 2,4-DCBA moiety, including conjugates for dietary risk assessment of 

food, as virtually all the residue data have been generated using a common moiety method that 

converts parent and all of the metabolites of concern to 2,4-DCBA. The tolerance expression 

should also be amended to include only propiconazole per se because 1) there are a number of 

pesticides that have 2,4-DCBA as common metabolite, and an enforcement agency may not be 

able to determine if residues are due to misuse of propiconazole or the proper use of other 

pesticides containing 2,4-DCBA; 2) propiconazole per se can be detected by FDA multiresidue 

methods; and 3) inclusion of only parent allows harmonization with the residue definition for the 

Codex MRLs. 

860.1300 Nature of the Residue – Livestock. 

The nature of propiconazole residues in livestock is adequately understood based on acceptable 

goat and poultry metabolism studies (DP D329394, Y. Donovan, 6/15/06). The Agency 

concluded that parent and all metabolites convertible to 2,4-DCBA are residues of concern for 

risk assessment, as the analytical method is a common moiety method that detects all residues 

convertible to 2,4-DCBA. However, for tolerance enforcement purposes, the current tolerance 

expression should be amended to include only propiconazole per se. 

860.1340 Residue Analytical Methods. 

Plant commodities: Samples were analyzed for propiconazole as 2,4-dichlorobenzoic methyl ester 

using the working method “Working Analytical Method for the Determination of Propiconazole in 

Mint Leaves as 2,4-Dichlorobenzoic Methyl Ester Using Gas Chromatography with Electron Capture 

Detector”. This method was adapted from “Determination of Total Residues of Propiconazole in 

Crops as 2,4-Dichlorobenzoic Acid by Capillary Gas Chromatography” (Method No. AG-454B). 

Minor modifications were made to improve the performance of the method. Briefly, samples were 

extracted by refluxing with 20% concentrated ammonium hydroxide/methanol for 1 hour. The 

mixture was cooled and filtered. An aliquot of the extract was evaporated to dryness and the residue 

dissolved in NaOH. The sample was then heated for 1 hour and 15 minutes with potassium 

permanganate, where propiconazole and its metabolites were converted to 2,4-dichlorobenzoic acid. 
Propiconazole Summary of Analytical Chemistry and Residue Data DP# 372878

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After addition of water, the sample was partitioned with 10% diethyl ether/hexane. The organic 

phase containing 2,4-dichlorobenzoic acid was evaporated to dryness and derivatized with 

diazomethane in the presence of dodecane, which acts as a keeper to reduce losses due to the 

volatility of the derivative in subsequent steps. The derivative was cleaned up using an acidic 

alumina column. The cleaned extract was quantified by gas chromatography with electron capture 

detection. A conversion factor of 1.79 was used to convert residues to propiconazole equivalents. The 

lowest level of method validation (LLMV) in this study was 0.050 ppm. Based on recoveries of 

samples fortified at the LLMV, the limit of detection (LOD) and limit of quantitation (LOQ) were 

calculated as 0.023 ppm and 0.070 ppm, respectively. 

For enforcement purposes, residue Method AG-354 is available for determining propiconazole 

per se in/on plant commodities using gas chromatography and flame ionization detection, and the 

reported LOQ is 0.05 ppm. In addition, Multiresidue Methods Section 302 can also be used to 

detect parent propiconazole. 

Animal commodities: No commodities in this petition are fed to livestock. 

 

GLN 860.1360: Multiresidue Methods 

The FDA PESTDATA database (PAM Volume I, Appendix I) indicates that propiconazole is 

completely recovered (>80%) using Multiresidue Methods Section 302. The recovery of 

propiconazole metabolites CGA-91305, CGA-118244, and 1,2,4-triazole is variable using 

Section 302. Propiconazole and metabolites CGA-91305, CGA-118244, and 1,2,4-triazole are 

not recovered using Multiresidue Methods Sections 303 and 304. 

860.1380 Storage Stability. 

Adequate storage stability data are available indicating that residues of propiconazole and its 

metabolites determined as 2,4-DCBA are stable at ≤-15 C for up to 39 months in a variety of 

commodities. (D329394, Y. Donovan, 6/15/06). 

860.1400 Water, Fish, and Irrigated Crops 

This guideline requirement is not relevant to the current petition as no uses are being proposed 

in/on water, fish, or irrigated crop for propiconazole. 

 

860.1460 Food Handling

This guideline requirement is not relevant to the current petition as no food handling uses are 

being proposed for propiconazole. 

860.1480 Meat, Milk, Poultry, and Eggs 

 This guideline requirement is not relevant to the current petition as no uses in/on feedstuffs are 

being proposed for propiconazole. 
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860.1500 Crop Field Trials 

47929501.der 

Field trials have submitted supporting the amended uses for propiconazole (EC) on mint. The 

results from these studies are discussed below and summarized in Table 7. 

Table 7. Summary of Residue Data from Mint Field Trials with Propiconazole.

Crop/ 

Commodity MRID# 

Total Appl. 

Rate 

(lb ai/A) 

End-use 

Product 

PHI 

(days) 

Combined Residues (ppm) 1

n Min. Max. HAFT2 Median 3 

(STMdR)

Mean 3

(STMR)

Std. 

Dev. 

Mint (0.225 lb ai/A total application rate, 30-day PHI) 

Mint, hay 4792501 0.1125 (1x) 3.6 lb/gal 

EC 7 10 0.114 5.453 5.446 3.556 3.316 1.977 

1

 Unless otherwise indicated, total propiconazole residues were determined as 2,4-DCBA and are expressed in parent 

equivalents. The method LOQ for propiconazole residues is 0.07 ppm The LOD is 0.023 ppm. 2

 HAFT = Highest Average Field Trial. 

3

 STMdR = Supervised Trial Median Residue; STMR = Supervised Trial Mean Residue. 4

 The field trial application rate relative to the maximum proposed use rate is listed in parentheses. 

Mint. In five field trials conducted during 1995 in Regions 5 and 11 (44416501.der), 

propiconazole (3.6 lb/gal EC) was applied 3 times to established fields of mint as broadcast foliar 

applications at 0.1125 lb ai/A/application at RTIs of 6-8 days, for a total of 0.3375 lb ai/A/season 

(1x rate). The initial application was made when plants were 2-4 inches in height, and all 

applications were made using ground equipment. Duplicate control and treated samples of fresh 

mint hay were harvested from each site at 7 DAT. Samples were stored frozen from collection to 

analysis for up to 294 days, an interval supported by available storage stability data. Total 

residues of propiconazole and its DCBA containing metabolites in/on mint were determined 

using a GC/ECD Method AG-454B, which was adequately validated in conjunction with the 

analysis of field trial samples. The validated method LOQ is 0.07 ppm, and an LOD is 0.023 

ppm. 

Following applications of propiconazole (EC) at rates totaling 0.1125 lb ai/A/season (1x rate), 

total propiconazole residues were 0.114-5.453 ppm and averaged 3.316 ppm in/on 10 samples of 

mint hay harvested at 7 DAT. 

Conclusions: The available field trial data are adequate and support the proposed amended use 

patterns for propiconazole on mint. The number and geographic distribution of the field trials 

are adequate, and the appropriate samples were collected at the proposed PHI. Data were 

generated for only the EC formulation. 

Other: The existing tolerances for berry group 13 (1.0 ppm), onion, bulb (0.2 ppm), onion, 

green (9.0 ppm), and strawberry (1.3 ppm) are adequate to cover any propiconazole residues 

under new crop groupings: onion, bulb subgroup 3-07A (0.2 ppm), onion, green subgroup 3-

07B (9.0 ppm), caneberry subgroup 13-07A (1.0 ppm), bushberry subgroup 13-07B (1.0 ppm), 

and low growing berry subgroup 13-07G (except cranberry) (1.3 ppm). 
Propiconazole Summary of Analytical Chemistry and Residue Data DP# 372878

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860.1520 Processed Food and Feed 

Mint. Adequate data are available from two mint processing studies (DP Barcode D209468, W. 

Wassell, 4/25/95). In two field trials, propiconazole (EC) was applied to mint at rates up to 0.34 

lb ai/A (1.5x labeled rate). Samples of fresh mint hay were cut 90 DAT, air dried, and distilled 

to yield mint oil. Samples of mint hay and oil were stored for up to 224 days prior to analysis 

using an adequate GC/ECD method (AG-454B). Total propiconazole residues were 0.12 ppm in 

fresh hay from both field trials and were <0.05 and 0.08 ppm in oil from the two sites, for an 

average processing factor of 0.5x for mint oil. Therefore, a separate tolerance for mint oil is not 

required. 

Conclusions: Adequate processing studies, reflecting the measurement of total combined 

residues, are available for mint. 

860.1650 Submittal of Analytical Reference Standards 

An analytical reference standard for propiconazole is available at the EPA National Pesticide 

Standards Repository. 

860.1850/860.1900 Confined and Field Accumulation in Rotational Crops 

The nature of the residue in confined rotational crops is understood (D329394, Y. Donovan, 

6/15/06). Based on acceptable studies previously reviewed by EFED, the metabolism of 

propiconazole in rotational crops is similar to that in primary crops. Plant-back restrictions have 

been established for propiconazole products registered for use on rotational crops based on the 

confined rotational crop studies. Labels specify that any food/feed crops not listed on the label 

should not be planted within 105 days of treatment. Tolerances for inadvertent residues of 

propiconazole in/on alfalfa planted in rotation with propiconazole-treated crops have been 

established at 0.1 ppm for alfalfa forage and hay. 

860.1550 Proposed Tolerances 

Permanent tolerances are currently established for the combined residues of propiconazole and 

its 2,4-DCBA containing metabolites at levels ranging from 0.1-40 ppm in/on plant commodities 

[40 CFR §180.434(a)]. Permanent tolerances are also established for the combined residues of 

propiconazole and its 2,4-DCBA containing metabolites at 0.1 ppm in fat, meat, and meat 

byproducts (except liver and kidney) of livestock, 2.0 ppm in liver and kidney of livestock, and 

at 0.05 ppm in milk; however, no tolerances have been established for eggs and poultry 

commodities. However, HED has determined that the current tolerance expression for plant and 

animal commodities is not appropriate and has previously recommended that the tolerance 

expression be revised to include only parent. 

Tolerances for peppermint and spearmint tops are to be increased from 3.5 to 10.0 ppm. 

Existing tolerances for berry group 13 (1.0 ppm), onion, bulb (0.2 ppm), onion, green (9.0 ppm), 

and strawberry (1.3 ppm) are to removed and the same tolerances to be reestablished under new 

crop groupings: onion, bulb subgroup 3-07A (0.2 ppm), onion, green subgroup 3-07B (9.0 
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ppm), caneberry subgroup 13-07A (1.0 ppm), bushberry subgroup 13-07B (1.0 ppm), and low 

growing berry subgroup 13-07G (except cranberry) (1.3 ppm). 

The Codex Alimentarius Commission has established several maximum residue limits (MRLs) 

for propiconazole in/on various raw agricultural commodities. The Codex MRLs are expressed 

in terms of propiconazole per se, which is the same as the US tolerance expression, 

recommended by the RED for existing tolerances and for the new uses. In addition, both Canada 

and Mexico have established MRLs/tolerances on several commodities which also have U.S. 

tolerances. To the extent possible, U.S. tolerances have been harmonized with Codex, Canadian, 

and Mexican MRLs. 

Table 9. Tolerance Summary for Propiconazole 

Crop Commodity 

Proposed or 

Established 

Tolerance 

(ppm)

HED 

Recommended 

Tolerance 

(ppm) 

Comments 

(Correct Commodity Definition)

Tolerances under §180.434(a) to be Removed 

Crop Group 13- Berries Group 1.0 Remove 

Mint, spearmint, tops 3.5 Remove 

Mint, peppermint, tops 3.5 Remove 

Onion, bulb 0.3 Remove 

Onion, green 9.0 Remove 

Strawberry 1.3 Remove 

 

Tolerances under §180.434(a) to be Added

Mint, spearmint, tops 3.5 10.0 Data are adequate to support the use. 

Mint, peppermint, tops 3.5 10.0 Data are adequate to support the use. 

Onion, bulb subgroup 3-07A 0.2 0.2 Data are adequate to support the use. 

Onion, green, subgroup 3-07B 9.0 9.0 Data are adequate to support the use. 

Caneberry, subgroup 13-07A 1.0 1.0 Data are adequate to support the use. 

Bushberry, subgroup 13-07B 1.0 1.0 Data are adequate to support the use. 

Low growing berry subgroup 

13-07G, except cranberry 1.3 1.3 

Tolerance is currently established for 

strawberry. Data are adequate to support 

the use. 
Propiconazole Summary of Analytical Chemistry and Residue Data DP# 372878

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References

DP Barcode: D329394 

Subject: Propiconazole (122101): Reregistration Eligibility Decision (RED) Document; 

Revised Residue Chemistry Considerations. 

From: Y. Donovan 

To: M. Goodis and C. Scheltema 

Dated: 6/15/06 

MRID(s): None 

 

DP Barcode: D219664 

Subject: PP#5F04591, Propiconazole on the Berry Crop Grouping, Carrots, and Onions 

(green and dry bulb). 

From: L. Kutney 

To: D. McCall 

Dated: 6/14/96 

MRID(s): 43786401-43786404 

DP Barcode: D209468 

Subject: PP#2E04047. Propiconazole (Tilt® Fungicide) in or on Mint. Amendment 

submitted on 10/24/94. 

From: Y. Donovan 

To: H. Jamerson and J. Smith 

Dated: 4/25/95 

MRID(s): 43424601 

 

Attachments: 

Appendix I - International Residue Limits Status 
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Appendix I – International Residue Limits 

INTERNATIONAL RESIDUE LIMIT STATUS 

Chemical Name: 1-[[2-(2,4-

dichlorophenyl)-4-propyl1,3-dioxolan-2-yl]methyl]-

1H-1,2,4-triazole 

Common Name: 

 Propiconazole 

 Proposed tolerances 

 Reevaluated tolerance 

X Other 

Date: 09/14/10 

Codex Status (Maximum Residue Limits) U. S. Tolerances 

X No Codex proposal step 6 or above 

 No Codex proposal step 6 or above for the crops 

requested 

Petition Number: 9E7659 

DP Barcode: D372878 

Other Identifier: 

Residue definition (step 8/CXL): Propiconazole Reviewer/Branch: J. Stokes/ RAB4 

Residue definition: 

Tolerances are currently expressed as the combined 

residues of propiconazole and its metabolites 

determined as 2,4-DCBA and expressed as parent. 

However, HED has recommended that the tolerance 

expression be changed to include only parent. 

Crop (s)1 MRL (mg/kg) Crop(s) Proposed or Established 

Tolerance (ppm) 

Mint, spearmint, tops 10.0 

Mint, peppermint, tops 10.0 

Onion, bulb subgroup 3-07A 0.2 

Onion, green, subgroup 3-07B 9.0 

Caneberry, subgroup 13-07A 1.0 

Bushberry, subgroup 13-07B 1.0 

Low growing berry subgroup 13-

07G, except cranberry 1.3 

 

Limits for Canada Limits for Mexico 

 No Limits 

 No Limits for the crops requested 

  No Limits 

 No Limits for the crops requested 

Residue definition: Propiconazole and its metabolites 

including the 2,4-DCBA moiety 

Residue definition: Propiconazole 

Crop(s) MRL (mg/kg) Crop(s) MRL (ppm) 

Dried blueberries 0.15 

Blueberries 0.02 

blackberries, 

loganberries and raspberries 

0.7 proposed 

Notes/Special Instructions: