Sulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

PC Code: 129081

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### UNITED STA TES ENVIRONMENTA L PROTECTION A GENCY WA SHINGTON, D.C. 20460 OFFICE OF CHEMICAL SAFETY AND POLL UTION P REVENTION 

### Date: 22 - DEC - 2010 Subject: Sulfentrazone

– R EVISED Acute and Chronic Aggregate Dietary (Food and

Drinkin g Water) Exposure and Risk Assessments for the Section 3 Registration Request to Add New Uses on: Brassica , Head and Stem, Subgroup 5A; Brassica , Leafy Greens, Subgroup 5B; Melon Subgroup 9A; Fruiting Vegetable, Group 8 and Okra; Pea, Succulent; Flax; Str awberry ; Tuberous and Corm Vegetable, Subgroup 1C ; and Miscellaneous Fruiting Vegetables . PC Code: 129081 DP Barcode: D384090 Decision No.: 388050 Registration Nos : 279 - 3220 & 279 - 3189 Petition No.: 7E7308 Regulatory Action: Amended Section 3 Risk Assessment Type: Dietary Case No.: 7231 T XR No.: NA CAS No.: 122836 - 35 - 5 MRID No.: N A 40 CFR: §180.498 

### From: Julie L. Van Alstine , MPH, Environmental Health Scientist

R isk A ssessment Branch 1 (RAB1) Health Effects Division (HED, 7509P) Through: Nancy

Dodd, Chemist Mohsen Sahafey an, Chemist Dietary Exposure Science Advisory Council (DESAC) a nd George F. Kramer, Ph.D., Branch Senior Chemist RAB1/HED (7509P) To: Barbara Madden RM05

Registration Division (RD; 7505P) a nd Kelly L owe , Risk Assessor RAB1/HED (7509P) NOTE : This document supersedes Memo, W. Wassell , 03 - APR - 2009 ( D362644) and Memo, J. Van Alstine , 18 - AUG - 2010 ( D364912 ) . This assessment has been updated to include revisions to the acute reference dose fo r females 13 - 49 y ears old .Sulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

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### Executive Summary A cute and chronic aggregate dietary (food and drinking water) exposure and risk assessments were conducted using the Dietary Exposure Evaluation Model - Food Consumption I ntake Database (DEEM - FCID  

### , ver. 2.0 3 ) . DE E M - FCID  

### incorporates food consumption data from the United States Department of Agriculture (USDA) Continuing Survey s of Food Intakes by Individuals (CSFII; 1994 - 1996 and 1998). The revised assessment is being conducted in support of new use s on B rassica , head and stem, s ubgroup 5 A ; Brassica , l eaf y g reen s, s ubgroup 5 B ; m elon s ubgroup 9 A; fruiting v egetable, g roup 8 and o kra; p ea, s u cculent; f lax; s trawberry ; t uberous and c orm v egetable, s ubgroup 1 C ; and miscellaneous fruiting vegetables; and change s to the toxicological doses and endpoints for sulfentrazone. Acute Dietary

(Food and Drinking Water) Exposure Results and Characterization The acute anal ys is assumed tolerance - level residues for all commodities , 100% crop treated ( % CT) , and DEEM  

### (v er. 7.81) default processing factors (as necessary ) . The acute anal ys is also incorporated the drinking water estimates provided by the Environmental Fate and Effects Division ( EFED ) . The resulting acute food plus water risk estimates are below HED ’s leve l of concern [ <100% of the acute population - adjusted dose (aPAD) ] at the 95 th 

### percentile of the exposure distribution for the U . S . general population ( less than 1 % aPAD), and all population subgroups . T he aPAD is lower for females 13 to 49 y ears old . T he population subgroup with the greatest risk was females 13 to 49 y ears old which utilized less than 3% of the aPAD. Chronic Dietary

(Food and Drinking Water) Exposure Results and Characterization The chr onic anal ys is assumed tole rance - level residues , 100% CT , and DEEM  

### (ver. 7.81) default processing factors (as necessary ) for all commodities. The chronic anal ys is also incorporated the drinking water estimates provided by EFED. The resulting chronic risk estimates are below HED’s level of concern . T he most highly exposed population subgroup was children 1 - 2 y ears old , which utilized less than 4 % of the chronic PAD (cPAD) . Cancer Dietary

(Food and Drinking Water) Exposure Results and Characterization A cancer dietary

assessment was not conducted because sulfentrazone is classified as “not likely to be carcinogenic to humans.” I. Introduction Dietary risk assessment incorporates both exposure and toxicity of a given pesticide. For acute and chronic assessments, the risk is exp ressed as a percentage of a maximum acceptable dose (i.e., the dose which HED has concluded will result in no unreasonable adverse health effects). This dose is referred to as the PAD. The PAD is equivalent to a point - of - departure [ POD; e.g., no - observab le - adverse - effect - level (NOAEL) ] divided by the required uncertainty

or safet y factors. For acute and non - cancer chronic exposures, HED is concerned when estimated dietary risk exceeds 100% of the PAD. References which discuss the acute and chronic risk assessmentsSulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

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### in more detail are available on the EPA/pesticides web site: “Available Information on Assessing Exposure from Pesticides, A User’s Guide,” 6/21/2000, web link: ht tp://www.epa.gov/fedrgstr/EPA - PEST/2000/July /Day - 12/6061.pdf

; or see SOP 99.6 (8/20/99). The most recent sulfentrazone dietary exposure assessment was conducted by J. Van Alstine (18 - AUG - 2010; D364912 ) . II. Residue Information Residues of Concern in Plants and Livestock: The HED Metabolism Assessment Review Committee (MARC) has determined that the parent compound, sulfentrazone, and the metabolite HMS [ N - (2,4 - dichloro - 5 - (4 - (difluorometh yl ) - 4,5 - dihy dro - 3 - hy drox ym eth yl - 5 - oxo - 1 H - 1,2,4 - triazol - yl )phen yl )methanesulfonamide)] are the residues of concern in so yb eans, and that sulfentrazone and its metabolites HMS and DMS [( N - 2,4 - dichloro - 5 - [4 - (difluoromethy l) - 4,5 - dihy dro - 5 - oxo - 1 H

- 1,2,4 - triazol - 1 - yl )pheny l)methanesulfonamide] are the residues of concern in rotational crops (Memo, G. Kramer, 14 - JUN - 1996; D226434) . HED has concluded that the results of the rotational crop metabolism studies may be translated to support preemergent uses on all ty pes of crops. Additionally , sulfentrazone and its metabolites HM S and DMS were identified as the residues of concern in meat, milk, poultry , and eggs. The HED MARC recommended that parent and 3 - carbox yl ic acid sulfentrazone are the residues of concern for the drinking - water assessment (Memo, G. Kramer et al. , 10 - APR - 2 003; D288713) . HED continues to consider the given metabolites and degradates to be the residues of concern for risk assessment. Established/Recommended Tolerances: A tolerance is currently established under 40 CFR §180.498(a)(1) for the combined residues of sulfentrazone and its major metabolite, HMS, in/on soy bean seed at 0.05 ppm. I n addition, permanent tolerances are established under 40 CFR §180.498(a)(2) for the combined residues of sulfentrazone and its metabolites HMS and DMS in/on several food commodities; these established tolerances range from 0.15 ppm (various plant commodities) to 0.40 ppm (peanut meal). Time - limited tolerances for the combined residues of sulfentrazone and its metabolites HMS and DMS have been estab lished under 40 CFR §180.498(b) in connection with Section 18 E mergency E xemptions ; these include tolerances for residues in/on bean, succulent - seed without pod (lima bean and cowpea) at 0.1 ppm with a 12/31/07 expiration date, flax seed at 0.2 0 ppm with a 12/31/10 expiration date, and strawberry at 0.60 ppm with a 12/31/10 expiration date. Finally , tolerances are established under 40 CFR §180.498(d) for inadvertent and indirect combined residues of sulfentrazone and its metabolites HMS and DMS in/on cerea l grain (excluding sweet corn) bran, forage, grain, hay , hulls, stover, and straw at 0.1 - 0.6 ppm as a result of the application of sulfentrazone to growing crops. The proposed uses and the submitted data support the establishment of the following toleranc es for the combined residues of sulfentrazone an d its metabolites HMS and DMS in/on:

Brassica , head and stem, subgroup 5A ....................... 0.20 ppm Brassica , leafy

greens, subgroup 5B ........................... 0.40 ppm Melon subgroup 9A ................................ .................... 0.15 ppm Vegetable, fruiting, group 8 ................................ ........ 0.15 ppm Okra ................................ ................................ ............. 0.15 ppmSulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

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### Pea, succulent ................................ .............................. 0.15 ppm Flax ................................ ................................ ............. 0.15 ppm Strawberry ................................ ................................ ... 0.15 ppm Vegetable, tuberous and corm, subgroup 1C .............. 0.15 ppm Cocona ................................ ................................ ........ 0.15 ppm Eggplant, African ................................ ........................ 0.15 ppm Eggplant, pea ................................ ............................... 0.15 ppm Eggplant, scarlet ................................ .......................... 0.15 ppm Goji berry ................................ ................................ .... 0.15 ppm Huckleberry , garden ................................ .................... 0.15 ppm Marty nia ................................ ................................ ...... 0.15 ppm Naranjilla ................................ ................................ ..... 0.15 ppm Roselle ................................ ................................ ......... 0.15 ppm Sunberry ................................ ................................ ...... 0.15 ppm Tomato, bush ................................ ............................... 0.15 ppm Tomato, currant ................................ ........................... 0.15 ppm Tomato, tree ................................ ................................ 0.15 ppm Residues used in the Acute and Chronic Analys e s : The se analy s e s employ ed tolerance - level residues for all commodities , 100% CT , and DEEM  

### (ver. 7.81) default processing factors . The following fruiting vegetables are not listed in DEEM - FCID  

### and were therefore not incl uded in the chronic assessment: cocona, African eggplant, pea eggplant, scarlet eggplant, goji berry , g arden huckleberry , mart ynia, naranjilla, roselle, sunberry, bush tomato, and currant tomato. However, tree tomato is included in DEEM  

### and was therefore included in the acute and chronic assessment s . I II. Estimated Drinking Water Concentrations D rinkin g water residues were incorporated directly into the acute and chronic dietary analy ses ( “water, direct, all sources” and “water, indirect, all sources”) and were provided by EFED (Memo, 9/15/2009 , L. L iu , D 3 66552 ). The estimated dri nking water concentrations (EDWCs) were Tier 1 estimates for ground water using the SCI - GROW M odel (Screening Concentration In G ro und Water) and surface water using the FI RST M odel [ Food Quality Protection Act (FQPA) Index Reservoir Screening Tool ] for sul fentrazone and its major degradate, 3 - carbox yl ic acid sulfentrazone. The EDWCs were based on the use of sulfentrazone on sugarcane, cabbage, potatoes, mint, or horseradish. For surface water, the acute (peak) sulfentrazone value is 32.0 ppb and the annu al average value ranges from 0.5 ppb in alkaline or neutral waters (most common) to 5.1 ppb in acidic waters. The groundwater screening sulfentraz one concentration is 15.7 ppb. For 3 - carbox yl ic acid sulfentrazone, the acute peak is 3.8 ppb and the annual average is 2.7 ppb. For 3 - carbox yl ic acid sulfentrazone in groundwater, the concentration is 10.3 ppb. These values generall y represent upper - bound conservative estimates of the total residue concentrations that might be found in surface water and ground water due to the use of s ulfentrazone on sugarcane, cabbage, potatoes, mint , or horseradish. These crops were chosen for this assessment because the label permits use of the maximum application rate (0.375 lb ai/A ) and aerial application. Aerial applicat ion has the potential for most spray drift and is not compatible with incorporation which would reduceSulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

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### surface water conce ntration values. EDWCs of 0.0358 ppm and 0.026 ppm were used in the acute and chronic anal ys e s, respectively . Table 1. Estimated Tier 1 Concentrations of Sulfentrazone and 3 - Carboxylic Acid Sulfentrazone in Drinking Water Due to the Use of Sulfentrazone on Sugarcane, Cabbage, Potatoes, Mint , or Horseradish 1 .

Chemical Surface Water (ug/L) Gr oundwater (ug/L) Ac ute Chronic Ac ute and Chronic Sulfentrazone 32.0 5.1 15.7 3 - Carboxylic Acid Sulfentrazone 3.8 2.7 10.3 Total 35.8 7.8 26.0 1 These crops were chosen for this assessment because the label permits use of the maximum application rate (0.375 pounds active ingredient per acre) and aerial application. 

### IV . DEEM - FCID  

### Program and Consumption Information Sulfentrazone acute and chronic dietary exposure and risk a ssessments were conducted using DEEM - FCID  

### ( Ver . 2.03 ), which incorporates co nsumption data from USDA’s CSFII, ( 1994 - 1996 and 1998 data) . The 1994 - 19 96, 19 98 data are based on the reported consumption of more than 20,000 individuals over two non - consecutive survey day s. Foods “as consumed” (e.g., apple pie) are linked to EPA - defi ned food commodities (e.g. , apples, peeled fruit - cooked; fresh or N/S; baked; or wheat flour - cooked; fresh or N/S, baked) using publicl y available recipe translation files developed jointly by USDA/ARS and EPA. For chronic exposure assessment, consump tion data are averaged for the entire U.S. population and within population subgroups, but for acute exposure assessment are retained as individual consumption events. Based on anal ys is of the 1994 - 96, 98 CSFII consumption data, which took into account di etary patterns and survey

respondents, HED concluded that it is most appropriate to report risk for the following population subgroups: the general U.S. population, all infants (<1 y ear old), children 1 - 2 ye ars old , children 3 - 5 ye ars old , children 6 - 12 ye ars old , y outh 13 - 19 ye ars old , adults 20 - 49 ye ars old , females 13 - 49 ye ars old , and adults 50+ y ears old. For chronic dietary

exposure assessment, an estimate of the residue level in each food or food form (e.g., orange or orange juice) on the food commo dity residue list is multiplied by the average dail y consumption estimate for that food/food form to produce a residue intake estimate. The resulting residue intake estimate for each food/food form is summed with the residue intake estimates for all other food/food forms on the commodity residue list to arrive at the total average estimated exposure. Exposure is expressed in mg/kg bod y weight/day and as a percent of the cPAD. This procedure is performed for each population subgroup. For acute exposure a ssessments, individual one - day food consumption data are used on an individual - by - individual basis. The reported consumption amounts of each food item can be multiplied by

a residue point estimate and summed to obtain a total daily pesticide exposure for a deterministic exposure assessment, or “matched” in multiple random pairings with residue values and then summed in a probabilistic assessment. The resulting distribution of exposures is expressed as a percentage of the aPAD on both a user (i.e., only th ose who reported eating relevant commodities/food forms) and a per - capita (i.e., those who reported eating the relevant commoditiesSulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

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### as well as those who did not) basis. I n accordance with HED policy , per capita exposure and risk are reported for all tiers of analy sis. However, for T iers 1 and 2, an y significant differences in user vs. per capita exposure and risk are specificall y identified and noted in the risk assessment. V. Toxicological Information The RAB1 toxicologists have reevaluated the sulfen trazone database and updated the endpoints as necessary . The toxicological endpoints selected for sulfentrazone are summarized below in Table 2 . Table 2. Summary of Toxicological Doses and Endpoints for Sulfentrazone for Use in Hum an - Health Risk Asses sments. Exposure Scenario Point of

Departure Uncertainty/

FQPA Safety Factors RfD, PAD,

Level of Concern for Risk Assessment Study and Relevant Toxicological Effects Ac ute Dietary (Fem ales 13 - 49) NOAEL =

14 mg/kg/day UF A = 10X

UF H = 10X FQPA SF = 1 X aRfD = aPAD =

0.14 mg/kg/day 2 - Gen Reproductive Toxicity Study - Rat

Offspring Toxicity LOAEL= 33 (M) and 40 (F) m g/kg/day based on reduced prenatal viability (fetal & litter), reduced litter size, increased no. of stillborn pups, reduced pup and litte r postnatal survival and decreased pup body weights throughout lactation. Ac ute Dietary (General population including infants and children) NOAEL =

250 mg/kg/day UF A = 10X

UF H = 10X FQPA SF = 1X aRfD =aPAD =

2.5 mg/kg/day Ac ute - Neurotoxicity Study - Rat

LOAEL = 750 mg/kg/day based on increased incidence of clinical signs and FOB parameters and decreased motor activity. Chronic Dietary (all populations) NOAEL=

10 mg/kg/day UF A = 10X

UF H = 10X FQPA SF = 1X cRfD = cPAD =

0.10 mg/kg/day Prenatal Developme ntal Toxicity - Rat

Developmental LOAEL = 25 mg/kg/day, based upon decreased mean fetal w eights, and retardation in skeletal development evidenced by an increased number of litters w ith any variation and by decreased number of caudal vertebral and metacarp al ossification sites. Cancer (oral, dermal, inhalation) Classification: sulfentrazone is classified as “not likely to be carcinogenic to humans.” NOAEL = no - observed adverse - effect level. LOAEL = lowest - observed adverse - effect level. UF = uncertainty factor. UF A = extrapolation from animal to human (interspecies). UF H = potential variation in sensitivity among members of the human population (intraspecies). UF L = extrapolation for use of a LOAEL in the absence of a NOAEL. FQPA SF = FQPA Safety Fac tor. PAD = population - adjusted dose (a = acute, c = chronic). RfD = reference dose. MOE = margin of exposure, LOC = level of concern. 

### V I . Results/Discussion Acute and c hronic anal ys es were performed using DEEM - FCID  

### (ver. 2.03 ). DEEM - FCID  

### estimate s the dietary

exposure and risk of the U.S. population and various population subgroups. The results reported are for the general U.S. Population, all infants (<1 ye ar old), children 1 - 2Sulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

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### ye ars old , children 3 - 5 ye ars old , children 6 - 12 ye ars old , y outh 13 - 19 ye ars old , females 13 - 49 ye ars old , adults 20 - 49 years old , and adults 50+ ye ars old . The resulting acute food plus water risk estimates are below HED ’s level of concern (<100% aPAD) at the 95 th 

### percentile of the exposure distribution for the general U . S . population ( less than 1 % aPAD), and all population subgroups; the population subgroup with the greatest risk wa s females 13 to 49 y ears , which utilize d less than 3% of the aPAD. See Table 3 below for a summary of the results of the acute assessment. The resulting chronic risk estimates are also below HED ’s level of concern . The most highl y exposed population was children 1 - 2 y ears old which utilized less than 4 % of the cPAD. See Table 4 below for a summary of the results of the chronic assessment. Table 3 . Summary of Acute Dietary Exposure and Risk for Sulfentrazone at the 95 th Percentile. 1 Population Subgroup aPAD (m g/kg/day) Exposure (mg/kg/day) %aPAD General U.S. Population

2.5 0.004347 <1 .0 All Infants (< 1 year old) 0.009388 <1.0 Children 1 - 2 y ears old 0.008187 <1.0 Children 3 - 5 y ears old 0.007476 <1.0 Children 6 - 12 y ears old 0.005284 <1.0 Youth 13 - 19 y ears old 0.003695 <1.0 Ad ults 20 - 49 y ears old 0.003341 <1.0 Ad ults 50+ years old 0.002942 <1.0 Fem ales 13 - 49 years old 0 .1 4 0.003256 2.3 1 The population with the greatest risk is bolded. Table 4 . Summary of Chronic Dietary Exposure and Risk for Sulfentrazone . 1 Population Subgroup cPAD (m g/kg/day) Exposure (mg/kg/day) %cPAD General U.S. Population

0.1 0 0.001751 1.8 All Infants (< 1 year old) 0.003117 3.1 Children 1 - 2 years old 0.003565 3.6 Children 3 - 5 y ears old 0.003463 3.5 Children 6 - 12 y ears old 0.002404 2.4 Youth 13 - 19 y ears old 0.001660 1.7 Ad ults 20 - 49 y ears old 0.001492 1.5 Ad ults 50+ years old 0.001360 1.4 Fem ales 13 - 49 y ears old 0.001451 1.5 1 The population with the greatest risk is bolded. 

### VI I . Characterization of Inputs/Outputs The unrefined acute and chronic analy ses assumed tolerance - level residues for all commodities , 100% CT , and DEEM  

### (ver. 7.81) default processing factors (as necessary) . These ana ly ses are considered conservative and could be refined through the use of anticipated - residue estimatesSulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

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### (ARs) for all commodities, %CT data for registered commodities, and empirical processing factors. VII I . Conclusions The acute and chronic dietary exp osure and risk estimates for sulfentrazone are below HED’s level of concern. For food and drinking water acute exposure, the population subgroup with the greatest risk wa s females 13 to 49 y ears old, which utilized less than 3% of the aPAD. For food and drinking water chronic exposure, the most highly - exposed population subgroup was children 1 - 2 y ears old , which utiliz ed less than 4 % of the cPAD. The acute and chronic dietary exposure assessments support the new uses proposed for sulfentrazone . Attachments Attachment 1 : DEEM - FCI D  

### A cute Residue File. Attachment 2: DEEM - FCI D  

### Acute Exposure Estimates for the General Population I ncluding Infants and Children. Attachment 3 : DEEM - FCI D  

### Chronic Residue File. Attachment 4 : DEEM - FCI D  

### Chronic Exposure Estimates. RDI: DE SAC Reviewers: 19 - NOV - 20 10 ; G. Kramer 17 - NOV - 2010 DP No.: D384090 Petition No.: 7E7308 PC Code: 129081 J. L. Van Alstine : S - 1095 1 :Potomac Yard:703 - 603 - 8866 :7509P:RAB1Sulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

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### Attachment 1 : DEEM - FCID  A cute R esidue F ile . Filename: C: \ Documents and Settings \ jlangsda \ My Documents \ Chemicals \ Sulfentrazone \ November 2010 \ Sent to Reviewers \ 129081 - acute - 2009 - jml__01 DEC 2010.R98 Chemical: Sulfentrazone RfD(Chronic): .1 mg/kg bw/day NOEL(Chronic): 0 mg/kg bw/day RfD(Acute): 2.5 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/day Date created/last modified: 12 - 01 - 2010/09:50:36/8 Program ver. 2.03

-------------------------------------------------------------------------------- EPA Crop De f Res Adj.Factors Comment Code Grp Commodity Name (ppm) #1 #2

-------- ---- ------------------------------- ---------- ------ ------ ------- 01011900 1AB Horseradish 0.200000 1.000 1. 000 1E0631

Full comment: 1E06311; TLT 0.10 ppm, exp. 12/31/05 01030150 1CD Arrowroot, flour 0.150000 1.000 1.000 01030151 1CD Arrowroot, flour - babyfood 0.150000 1.000 1.000 01030170 1CD Artichoke, Jerusale m 0.150000 1.000 1.000 01030820 1CD Cassava 0.150000 1.000 1.000 01030821 1CD Cassava - babyfood 0.150000 1.000 1.000 01031390 1CD Dasheen, corm 0.150000 1.00 0 1.000 01031660 1CD Ginger 0.150000 1.000 1.000 01031661 1CD Ginger - babyfood 0.150000 1.000 1.000 01031670 1CD Ginger, dried 0.150000 1.000 1.000 01032960 1C Potato , chips 0.150000 1.000 1.000 01032970 1C Potato, dry (granules/ flakes) 0.150000 6.500 1.000 01032971 1C Potato, dry (granules/ flakes) - b 0.150000 6.500 1.000 01032980 1C Potato, flour 0. 150000 6.500 1.000 01032981 1C Potato, flour - babyfood 0.150000 6.500 1.000 01032990 1C Potato, tuber, w/peel 0.150000 1.000 1.000 01032991 1C Potato, tuber, w/peel - babyfood 0.150000 1.000 1.000 0103300 0 1C Potato, tuber, w/o peel 0.150000 1.000 1.000 01033001 1C Potato, tuber, w/o peel - babyfood 0.150000 1.000 1.000 01033660 1CD Sweet potato 0.150000 1.000 1.000 01033661 1CD Sweet potato - babyfood 0.150000 1.000 1.000 01033710 1CD Tanier, corm 0.150000 1.000 1.000 01033870 1CD Turmeric 0.150000 1.000 1.000 01034060 1CD Yam, true 0.150000 1.000 1. 000 01034070 1CD Yam bean 0.150000 1.000 1.000 05010610 5A Broccoli 0.200000 1.000 1.000 05010611 5A Broccoli - babyfood 0.200000 1.000 1.000 05010620 5A Broccoli, C hinese 0.200000 1.000 1.000 05010640 5A Brussels sprouts 0.200000 1.000 1.000 05010690 5A Cabbage 0.200000 1.000 1.000 1E0631

Full comment: 1E06311 05010710 5A Cabb age, Chinese, napa 0.200000 1.000 1.000 1E0631

Full comment: 1E06311 05010720 5A Cabbage, Chinese, mustard 0.200000 1.000 1.000 1E0631

Full comment: 1E06311 05010830 5A Cauliflower 0.200000 1.000 1.000 05011960 5A Kohlrabi 0.200000 1.000 1.000 05020630 5B Broccoli raab 0.400000 1.000 1.000 05020700 5B Cabbage, Chinese, bok choy 0.400000 1.000 1.000 1E063 1

Full comment: 1E06311 05021170 5B Collards 0.400000 1.000 1.000 05021940 5B Kale 0.400000 1.000 1.000 05022290 5B Mustard greens 0.400000 1.000 1.000 05023180 5B Rape greens 0.400000 1.000 1.000 05023890 5B Turnip, greens 0.400000 1.000 1.000 06003470 6 Soybean, seed 0.050000 1.000 1.000 06003480 6 Soybean, flour 0.050000 1.000 1.000 06003481 6 Soybean, flour - babyfood 0.050000 1.000 1.000 06003490 6 Soybean, soy milk 0.050000 1.000 1.000 06003491 6 Soybean, soy milk - babyfood or in 0.050000 1.000 1.000 06003500 6 Soybean, oil 0.050000 1.000 1.000 06003501 6 Soybean, oil - babyfood 0.050000 1.000 1.000 06010430 6A Bean, snap, succulent 0.150000 1.000 1.000 06010431 6A B ean, snap, succulent - babyfood 0.150000 1.000 1.000 06012570 6A Pea, edible podded, succulent 0.150000 1.000 1.000 06020310 6B Bean, broad, succulent 0.150000 1.000 1.000 06020330 6B Bean, cowpea, succulent 0.100000 1.000 1.000 TLT, eSulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

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Page 10 of 18 Full comment: TLT, exp. 12/31/04 06020370 6B Bean, lima, succulent 0.150000 1.000 1.000 06022550 6B Pea, succulent 0.150000 1.000 1.000 06022551 6B Pea, succulent - babyfood 0.150000 1.000 1.000 06022590 6B Pea, pigeon, succulent 0.150000 1.000 1.000 06030300 6C Bean, black, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030320 6C Bean, b road, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030340 6C Bean, cowpea, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030350 6C Bean, great northern, seed 0. 150000 1.000 1.000 2F0639

Full comment: 2F06391 06030360 6C Bean, kidney, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030380 6C Bean, lima, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030390 6C Bean, mung, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030400 6C Bean, navy, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F0639 1 06030410 6C Bean, pink, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030420 6C Bean, pinto, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030980 6C Chickpea, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030981 6C Chickpea, seed - babyfood 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030990 6C Chickpea, flour 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06031820 6C Guar, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06031821 6C Guar, seed - babyfood 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06032030 6C Lentil, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06032560 6C Pea, dry 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06032 561 6C Pea, dry - babyfood 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06032580 6C Pea, pigeon, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 08001480 8 Eggplant 0.150000 1.000 1.000 08002340 8 Okra 0.150000 1.000 1.000 08002700 8 Pepper, bell 0.150000 1.000 1.000 08002701 8 Pepper, bell - babyfood 0.150000 1.000 1.000 08002710 8 Pepper, bell, dried 0.150000 1.000 1.000 08002711 8 Pepper, bell, dried - babyfood 0.150000 1.000 1.000 08002720 8 Pepper, nonbell 0.150000 1.000 1.000 New, S

Full c omment: New, Section 18 08002721 8 Pepper, nonbell - babyfood 0.150000 1.000 1.000 New, S

Full comment: New, Section 18 08002730 8 Pepper, nonbell, dried 0.150000 1.000 1.000 New, S

Full comment: New, S ection 18 08003740 8 Tomatillo 0.150000 1.000 1.000 08003750 8 Tomato 0.150000 1.000 1.000 08003751 8 Tomato - babyfood 0.150000 1.000 1.000 08003760 8 Tomato, paste 0.150000 5.400 1.000 08003761 8 Tomato, paste - babyfood 0.150000 5.400 1.000 08003770 8 Tomato, puree 0.150000 3.300 1.000 08003771 8 Tomato, puree - babyfood 0.1 50000 3.300 1.000 08003780 8 Tomato, dried 0.150000 14.300 1.000 08003781 8 Tomato, dried - babyfood 0.150000 14.300 1.000 08003790 8 Tomato, juice 0.150000 1.500 1.000 09010750 9A Cantaloupe 0.150000 1.000 1.000 09010800 9A Casaba 0.150000 1.000 1.000 09011870 9A Honeydew melon 0.150000 1.000 1.000 09013990 9A Watermelon 0.150000 1.000 1.000 09014000 9A Watermelon, juice 0.150000 1.000 1.000 15000250 15 Barley, pearled barley 0.100000 1.000 1.000 InadveSulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

PC Code: 129081

____________________________________________________________________________________________

Page 11 of 18 Full comment: Inadvertent tol. 15000251 15 Barley, p earled barley - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15000260 15 Barley, flour 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15000261 15 Barley, flour - babyfoo d 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15000270 15 Barley, bran 0.150000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15000650 15 Buckwheat 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15000660 15 Buckwheat, flour 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15001200 15 Corn, field, flour 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001201 15 Corn, field, flour - babyfood 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001210 15 Corn, field, meal 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001211 15 Corn, field, meal - babyfood 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001220 15 Corn, field, bran 0.150000 1.000 1.000 Inadve

Full comment: Inadvertent to l. 15001230 15 Corn, field, starch 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001231 15 Corn, field, starch - babyfood 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001240 15 Corn, field, syrup 0.150000 1.500 1.000 2F0639

Full comment: 2F06391 15001241 15 Corn, field, syrup - babyfood 0.150000 1.500 1.000 2F0639

Full comment: 2F06391 15001250 15 Corn, field, oil 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001251 15 Corn, field, oil - babyfood 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001260 15 Corn, pop 0.100000 1.000 1.000 2F0639

Full comment: 2F06391 15002260 15 Millet, grain 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15002310 15 Oat, bran 0.150000 1.000 1.000 Inadve

Full comment: Ina dvertent tol. 15002320 15 Oat, flour 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15002321 15 Oat, flour - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol . 15002330 15 Oat, groats/rolled oats 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15002331 15 Oat, groats/rolled oats - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003230 1 5 Rice, white 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003231 15 Rice, white - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003240 15 Rice, br own 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003241 15 Rice, brown - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003250 15 Rice, flour 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003251 15 Rice, flour - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003260 15 Rice, bran 0.150000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003261 15 Rice, bran - babyfood 0.150000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003280 15 Rye, grain 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003290 15 Rye, flour 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003440 15 Sorghum, grain 0.100000 1.000 1.0 00 Inadve

Full comment: Inadvertent tol.Sulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

PC Code: 129081

____________________________________________________________________________________________

Page 12 of 18 15003450 15 Sorghum, syrup 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003810 15 Triticale, flour 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003811 15 Triticale, flour - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15004010 15 Wheat, grain 0.100000 1.000 1.000 Inadve

Ful l comment: Inadvertent tol. 15004011 15 Wheat, grain - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15004020 15 Wheat, flour 0.100000 1.000 1.000 Inadve

Full comment: I nadvertent tol. 15004021 15 Wheat, flour - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15004030 15 Wheat, germ 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent t ol. 15004040 15 Wheat, bran 0.150000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15004050 15 Wild rice 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 20001630 20 Flaxseed, oil 0.150000 1.000 1.000 20003640 20 Sunflower, seed 0.200000 1.000 1.000 20003650 20 Sunflower, oil 0.200000 1.000 1.000 20003651 20 Sunflower, oil - babyfood 0.200000 1.000 1.000 86010000 O Water, direct, all sources 0.035800 1.000 1.000 86020000 O Water, indirect, all sources 0.035800 1.000 1.000 95000190 O Asparagus 0.150000 1.000 1.0 00 2E0650

Full comment: 2E06500 95002630 O Peanut 0.200000 1.000 1.000 0F0611

Full comment: 0F06116 95002640 O Peanut, butter 0.200000 1.890 1.000 0F0611

Full comm ent: 0F06116 95002650 O Peanut, oil 0.200000 1.000 1.000 0F0611

Full comment: 0F06116 95002750 O Peppermint 0.300000 1.000 1.000 1E0631

Full comment: 1E06311 95002760 O Pep permint, oil 0.300000 1.000 1.000 1E0631

Full comment: 1E06311 95003520 O Spearmint 0.300000 1.000 1.000 1E0631

Full comment: 1E06311 95003530 O Spearmint, oil 0.300000 1.000 1.000 1E0631

Full comment: 1E06311 95003590 O Strawberry 0.150000 1.000 1.000 95003591 O Strawberry - babyfood 0.150000 1.000 1.000 95003600 O Strawberry, juice 0.150000 1.000 1.000 95003601 O Strawberry, juice - babyfood 0.150000 1.000 1.000 95003620 O Sugarcane, sugar 0.150000 1.000 1.000 95003621 O Sugarcane, sugar - babyfood 0.150000 1.000 1.00 0 95003630 O Sugarcane, molasses 0.200000 1.000 1.000 95003631 O Sugarcane, molasses - babyfood 0.200000 1.000 1.000 95003800 O Tomato, Tree 0.150000 1.000 1.000Sulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

PC Code: 129081

____________________________________________________________________________________________

Page 13 of 18 

### Att achment 2 : DEEM - FCID  A cute E xposure E stimates for the General Population including Infants and Children . 1 U.S. Environmental Protection Agency Ver. 2.02 DEEM - FCID ACUTE Analysis for SULFENTRAZONE (1 994 - 98 data) Residue file: 129081 - acute - 2009 - jml__01 DEC 2010.R98 Adjustment factor #2 used. Analysis Date: 12 - 01 - 2010/09:52:09 Residue file dated: 12 - 01 - 2010/09:50:36/8 Daily totals for food and foodform consumption used. Run Comment: ""

========== ===================================================================== Summary calculations (per capita): 95th Percentile 99th Percentile 99.9th Percentile Exposure % aRfD Exposure % aRfD Exposure % aRfD

---------- -------- ---------- -------- ---------- -------- U.S. Population: 0.004347 0.17 0.007110 0.28 0.011882 0.48 All infants: 0.009388 0.38 0.013235 0.53 0.020709 0.83 Children 1 - 2 yrs: 0.008187 0.33 0.011436 0.46 0.018298 0.73 Children 3 - 5 yrs: 0.007476 0.30 0.010856 0.43 0.017357 0.69 Children 6 - 12 yrs: 0.005284 0.21 0.007704 0.31 0.010870 0.43 Youth 13 - 19 yrs: 0.003695 0.15 0.005772 0.23 0.010982 0.44 Adults 20 - 49 yrs: 0.003341 0.13 0.004837 0.19 0.008144 0.33 Adults 50+ yrs: 0.002942 0.12 0.004081 0.16 0.006160 0.25 Females 13 - 49 yrs: 0.003256 0.13 2 0.004506 0.18 0.007684 0.31 1 The a PAD for the general population includin g infants and children = 2.5 mg/kg bw/day . The a PAD for f em ales 13 - 49 years old = 0.1 4 mg/kg bw/day. 2 This value was calculated by DEEM TM using an a PAD of 2.5 mg/kg bw/day. The % a PAD reported in Table 3 wa s adjusted to account for the lower a PAD (0.1 4 mg/kg bw/day) for females 13 - 49 years old using the follow ing formula: % aPAD = (Exposure/aPAD)*100% = (0.003256/0.1 4 )*100% = 2.3 % .Sulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

PC Code: 129081

____________________________________________________________________________________________

Page 14 of 18 

### Atta chment 3 : DEEM - FCID  C hronic R esidue F ile . Filename: C: \ Documents and Settings \ jlangsda \ My Documents \ Chemicals \ Sulfentrazone \ November 2010 \ Sent to Reviewers \ 129081 - chronic - 2009 - jml__01 DEC 2010.R98 Chemical: Sulfentrazone RfD(Chronic): .1 mg/kg bw/day NO EL(Chronic): 0 mg/kg bw/day RfD(Acute): 2.5 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/day Date created/last modified: 12 - 01 - 2010/09:51:00/8 Program ver. 2.03

-------------------------------------------------------------------------------- EPA Cr op Def Res Adj.Factors Comment Code Grp Commodity Name (ppm) #1 #2

-------- ---- ------------------------------- ---------- ------ ------ ------- 01011900 1AB Horseradish 0.200000 1.000 1.000 1E0631

Full comment: 1E06311; TLT 0.10 ppm, exp. 12/31/05 01030150 1CD Arrowroot, flour 0.150000 1.000 1.000 01030151 1CD Arrowroot, flour - babyfood 0.150000 1.000 1. 000 01030170 1CD Artichoke, Jerusalem 0.150000 1.000 1.000 01030820 1CD Cassava 0.150000 1.000 1.000 01030821 1CD Cassava - babyfood 0.150000 1.000 1.000 01031390 1CD Dasheen, co rm 0.150000 1.000 1.000 01031660 1CD Ginger 0.150000 1.000 1.000 01031661 1CD Ginger - babyfood 0.150000 1.000 1.000 01031670 1CD Ginger, dried 0.15000 0 1.000 1.000 01032960 1C Potato, chips 0.150000 1.000 1.000 01032970 1C Potato, dry (granules/ flakes) 0.150000 6.500 1.000 01032971 1C Potato, dry (granules/ flakes) - b 0.150000 6.500 1.000 01032980 1C Potato, flour 0.150000 6.500 1.000 01032981 1C Potato, flour - babyfood 0.150000 6.500 1.000 01032990 1C Potato, tuber, w/peel 0.150000 1.000 1.000 01032991 1C Potato, tuber, w/peel - babyfoo d 0.150000 1.000 1.000 01033000 1C Potato, tuber, w/o peel 0.150000 1.000 1.000 01033001 1C Potato, tuber, w/o peel - babyfood 0.150000 1.000 1.000 01033660 1CD Sweet potato 0.150000 1.000 1.000 01033661 1CD Sweet potato - babyfood 0.150000 1.000 1.000 01033710 1CD Tanier, corm 0.150000 1.000 1.000 01033870 1CD Turmeric 0.150000 1.000 1.000 01034060 1CD Yam, true 0.150000 1.000 1.000 01034070 1CD Yam bean 0.150000 1.000 1.000 05010610 5A Broccoli 0.200000 1.000 1.000 05010611 5A Broccoli - babyfood 0.200000 1 .000 1.000 05010620 5A Broccoli, Chinese 0.200000 1.000 1.000 05010640 5A Brussels sprouts 0.200000 1.000 1.000 05010690 5A Cabbage 0.200000 1.000 1.000 1E0631

F ull comment: 1E06311 05010710 5A Cabbage, Chinese, napa 0.200000 1.000 1.000 1E0631

Full comment: 1E06311 05010720 5A Cabbage, Chinese, mustard 0.200000 1.000 1.000 1E0631

Full comment: 1E06311 05010830 5A Cauliflower 0.200000 1.000 1.000 05011960 5A Kohlrabi 0.200000 1.000 1.000 05020630 5B Broccoli raab 0.400000 1.000 1.000 05020700 5B Cabbage, Chinese, bok choy 0.400000 1.000 1.000 1E0631

Full comment: 1E06311 05021170 5B Collards 0.400000 1.000 1.000 05021940 5B Kale 0.400000 1.000 1.000 05022290 5B Mustard greens 0.400000 1.000 1.000 05023180 5B Rape greens 0.400000 1.000 1.000 05023890 5B Turnip, greens 0.400000 1.000 1.000 06003470 6 Soybean, seed 0.050000 1.00 0 1.000 06003480 6 Soybean, flour 0.050000 1.000 1.000 06003481 6 Soybean, flour - babyfood 0.050000 1.000 1.000 06003490 6 Soybean, soy milk 0.050000 1.000 1.000 06003491 6 Soybea n, soy milk - babyfood or in 0.050000 1.000 1.000 06003500 6 Soybean, oil 0.050000 1.000 1.000 06003501 6 Soybean, oil - babyfood 0.050000 1.000 1.000 06010430 6A Bean, snap, succulent 0. 150000 1.000 1.000 06010431 6A Bean, snap, succulent - babyfood 0.150000 1.000 1.000 06012570 6A Pea, edible podded, succulent 0.150000 1.000 1.000 06020310 6B Bean, broad, succulent 0.150000 1.000 1.000 0602033 0 6B Bean, cowpea, succulent 0.100000 1.000 1.000 TLT, e

Full comment: TLT, exp. 12/31/04Sulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

PC Code: 129081

____________________________________________________________________________________________

Page 15 of 18 06020370 6B Bean, lima, succulent 0.150000 1.000 1.000 2E0649

Full comment: 2E06498 06022550 6B Pea, succule nt 0.150000 1.000 1.000 06022551 6B Pea, succulent - babyfood 0.150000 1.000 1.000 06022590 6B Pea, pigeon, succulent 0.150000 1.000 1.000 06030300 6C Bean, black, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030320 6C Bean, broad, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030340 6C Bean, cowpea, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030350 6C Bean, great northern, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030360 6C Bean, kidney, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 0603 0380 6C Bean, lima, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030390 6C Bean, mung, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030400 6C Bean, navy, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030410 6C Bean, pink, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030420 6C Bean, pinto, seed 0.150000 1.00 0 1.000 2F0639

Full comment: 2F06391 06030980 6C Chickpea, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06030981 6C Chickpea, seed - babyfood 0.150000 1.000 1.000 2F0639

Ful l comment: 2F06391 06030990 6C Chickpea, flour 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06031820 6C Guar, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06031821 6C Guar, seed - babyfood 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06032030 6C Lentil, seed 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06032560 6C Pea, dry 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06032561 6C Pea, dry - babyfood 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 06032580 6C Pea, pigeon, seed 0.150000 1.000 1.00 0 2F0639

Full comment: 2F06391 08001480 8 Eggplant 0.150000 1.000 1.000 08002340 8 Okra 0.150000 1.000 1.000 08002700 8 Pepper, bell 0.150000 1.00 0 1.000 08002701 8 Pepper, bell - babyfood 0.150000 1.000 1.000 08002710 8 Pepper, bell, dried 0.150000 1.000 1.000 08002711 8 Pepper, bell, dried - babyfood 0.150000 1.000 1.000 08002720 8 Pepper , nonbell 0.150000 1.000 1.000 New, S

Full comment: New, Section 18 08002721 8 Pepper, nonbell - babyfood 0.150000 1.000 1.000 New, S

Full comment: New, Section 18 08002730 8 Pepper, nonbell, dri ed 0.150000 1.000 1.000 New, S

Full comment: New, Section 18 08003740 8 Tomatillo 0.150000 1.000 1.000 08003750 8 Tomato 0.150000 1.000 1.000 08003751 8 Tomat o - babyfood 0.150000 1.000 1.000 08003760 8 Tomato, paste 0.150000 5.400 1.000 08003761 8 Tomato, paste - babyfood 0.150000 5.400 1.000 08003770 8 Tomato, puree 0 .150000 3.300 1.000 08003771 8 Tomato, puree - babyfood 0.150000 3.300 1.000 08003780 8 Tomato, dried 0.150000 14.300 1.000 08003781 8 Tomato, dried - babyfood 0.150000 14.300 1.000 080037 90 8 Tomato, juice 0.150000 1.500 1.000 09010750 9A Cantaloupe 0.150000 1.000 1.000 09010800 9A Casaba 0.150000 1.000 1.000 09011870 9A Honeydew melon 0.150000 1.000 1.000 09013990 9A Watermelon 0.150000 1.000 1.000 09014000 9A Watermelon, juice 0.150000 1.000 1.000 15000250 15 Barley, pearled barley 0.100000 1.000 1 .000 InadveSulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

PC Code: 129081

____________________________________________________________________________________________

Page 16 of 18 Full comment: Inadvertent tol. 15000251 15 Barley, pearled barley - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15000260 15 Barley, flour 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15000261 15 Barley, flour - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15000270 15 Barley, bran 0.150000 1.000 1.000 Inadve

F ull comment: Inadvertent tol. 15000650 15 Buckwheat 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15000660 15 Buckwheat, flour 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15001200 15 Corn, field, flour 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001201 15 Corn, field, flour - babyfood 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001210 15 Corn, field, meal 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001211 15 Corn, field, meal - babyfood 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001220 15 Corn, field, bran 0.150000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15001230 15 Corn, field, starch 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001231 15 Corn, field, starch - babyfood 0.150000 1.0 00 1.000 2F0639

Full comment: 2F06391 15001240 15 Corn, field, syrup 0.150000 1.500 1.000 2F0639

Full comment: 2F06391 15001241 15 Corn, field, syrup - babyfood 0.150000 1.500 1.000 2F0639

Fu ll comment: 2F06391 15001250 15 Corn, field, oil 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001251 15 Corn, field, oil - babyfood 0.150000 1.000 1.000 2F0639

Full comment: 2F06391 15001260 1 5 Corn, pop 0.100000 1.000 1.000 2F0639

Full comment: 2F06391 15002260 15 Millet, grain 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15002310 15 Oat, bran 0.150000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15002320 15 Oat, flour 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15002321 15 Oat, flour - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15002330 15 Oat, groats/rolled oats 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15002331 15 Oat, groats/rolled oats - babyfood 0.1000 00 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003230 15 Rice, white 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003231 15 Rice, white - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003240 15 Rice, brown 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003241 15 Rice, brown - babyfood 0.100000 1.000 1.000 Inadv e

Full comment: Inadvertent tol. 15003250 15 Rice, flour 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003251 15 Rice, flour - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003260 15 Rice, bran 0.150000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003261 15 Rice, bran - babyfood 0.150000 1.000 1.000 Inadve

Full comment : Inadvertent tol. 15003280 15 Rye, grain 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003290 15 Rye, flour 0.100000 1.000 1.000 Inadve

Full comment: Inadverten t tol. 15003440 15 Sorghum, grain 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol.Sulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

PC Code: 129081

____________________________________________________________________________________________

Page 17 of 18 15003450 15 Sorghum, syrup 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003 810 15 Triticale, flour 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15003811 15 Triticale, flour - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15004010 15 Whe at, grain 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15004011 15 Wheat, grain - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15004020 15 Wheat, flour 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15004021 15 Wheat, flour - babyfood 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15004030 15 Wheat, germ 0.100000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15004040 15 Wheat, bran 0.150000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 15004050 15 Wild rice 0.10 0000 1.000 1.000 Inadve

Full comment: Inadvertent tol. 20001630 20 Flaxseed, oil 0.150000 1.000 1.000 20003640 20 Sunflower, seed 0.200000 1.000 1.000 20003650 20 Sunflower, oil 0.200000 1.000 1.000 20003651 20 Sunflower, oil - babyfood 0.200000 1.000 1.000 86010000 O Water, direct, all sources 0.026000 1.000 1.000 86020000 O Water, indirect, all sources 0.026000 1.000 1 .000 95000190 O Asparagus 0.150000 1.000 1.000 2E0650

Full comment: 2E06500 95002630 O Peanut 0.200000 1.000 1.000 0F0611

Full comment: 0F06116 95002640 O Peanut, b utter 0.200000 1.890 1.000 0F0611

Full comment: 0F06116 95002650 O Peanut, oil 0.200000 1.000 1.000 0F0611

Full comment: 0F06116 95002750 O Peppermint 0.30 0000 1.000 1.000 1E0631

Full comment: 1E06311 95002760 O Peppermint, oil 0.300000 1.000 1.000 1E0631

Full comment: 1E06311 95003520 O Spearmint 0.300000 1.000 1.000 1E0631

Full comment: 1E06311 95003530 O Spearmint, oil 0.300000 1.000 1.000 1E0631

Full comment: 1E06311 95003590 O Strawberry 0.150000 1.000 1.000 95003591 O Strawberry - babyfood 0.150000 1.000 1.000 95003600 O Strawberry, juice 0.150000 1.000 1.000 95003601 O Strawberry, juice - babyfood 0.150000 1.000 1.000 95003620 O Sugarcane, sugar 0.150000 1.000 1. 000 95003621 O Sugarcane, sugar - babyfood 0.150000 1.000 1.000 95003630 O Sugarcane, molasses 0.200000 1.000 1.000 95003631 O Sugarcane, molasses - babyfood 0.200000 1.000 1.000 95003800 O Tomato, Tre e 0.150000 1.000 1.000Sulfentrazone Dietary Exposure and Risk Assessm ent DP Number: D 384090

PC Code: 129081

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Page 18 of 18 

### Attachment 4 : DEEM - FCID  C hronic E xposure E stimates . U.S. Environmental Protection Agency Ver. 2.00 DEEM - FCID Chronic analysis for SULFENTRAZONE (1994 - 98 data) Residue file name: C: \ Documents and Settings \ jlangsda \ My Documents \ Chemicals \ Sulfentrazone \ November 2010 \ Sent to Reviewers \ 129081 - chronic - 2009 - jml__01 DEC 2010.R98 Adjustment factor #2 used. Analysis Date 12 - 01 - 2010/10:00:17 Residue file dated: 12 - 01 - 2010/09:51:00/8 Reference dose (RfD, Chronic) = .1 mg/kg bw/day

=============================================================================== Total exposure by p opulation subgroup

------------------------------------------------------------------------------- Total Exposure

----------------------------------- Po pulation mg/kg Percent of Subgroup body wt/day Rfd

-------------------------------------- ------------- --------------- U.S. Population (total) 0.001751 1.8% U.S. Population (spring season) 0.001760 1.8% U.S. Population (summer season) 0.001841 1.8% U.S. Population (autumn season) 0.001701 1 .7% U.S. Population (winter season) 0.001700 1.7% Northeast region 0.001667 1.7% Midwest region 0.001810 1.8% Southern region 0.001696 1.7% Western region 0.001849 1.8% Hispanics 0.001922 1.9% Non - hispanic whites 0.001704 1.7% Non - hispanic blacks 0.001782 1.8% Non - hisp/non - white/non - black 0.002025 2.0% All infants (< 1 year) 0.003117 3.1% Nursing infants 0.001240 1.2% Non - nursing infants 0.003829 3.8% Children 1 - 6 yrs 0.003430 3.4% Children 7 - 12 yrs 0.002286 2.3% Females 13 - 19 (not preg or nursing) 0.001519 1.5% Females 20+ (not preg or nursing) 0.001400 1.4% Females 13 - 50 yrs 0.001534 1.5% Females 13+ (p reg/not nursing) 0.001513 1.5% Females 13+ (nursing) 0.001853 1.9% Males 13 - 19 yrs 0.001796 1.8% Males 20+ yrs 0.0 01485 1.5% Seniors 55+ 0.001352 1.4% Children 1 - 2 yrs 0.003565 3.6% Children 3 - 5 yrs 0.003463 3.5% Childr en 6 - 12 yrs 0.002404 2.4% Youth 13 - 19 yrs 0.001660 1.7% Adults 20 - 49 yrs 0.001492 1.5% Adults 50+ yrs 0.001360 1.4% Females 13 - 49 yrs 0.001451 1.5%

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