Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

PC Code: 129081

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UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C. 20460

OFFICE OF

CHEMICAL SAFETY AND

POLLUTION PREVENTION

Date: 22-DEC-2010

Subject: Sulfentrazone – REVISED Acute and Chronic Aggregate Dietary (Food and 

Drinking Water) Exposure and Risk Assessments for the Section 3 Registration 

Request to Add New Uses on: Brassica, Head and Stem, Subgroup 5A; Brassica, 

Leafy Greens, Subgroup 5B; Melon Subgroup 9A; Fruiting Vegetable, Group 8 and 

Okra; Pea, Succulent; Flax; Strawberry; Tuberous and Corm Vegetable, Subgroup 

1C; and Miscellaneous Fruiting Vegetables. 

PC Code: 129081 DP Barcode: D384090

Decision No.: 388050 Registration Nos: 279-3220 & 279-3189

Petition No.: 7E7308 Regulatory Action: Amended Section 3

Risk Assessment Type: Dietary Case No.: 7231

TXR No.: NA CAS No.: 122836-35-5

MRID No.: NA 40 CFR: §180.498

From: Julie L. Van Alstine, MPH, Environmental Health Scientist

Risk Assessment Branch 1 (RAB1)

Health Effects Division (HED, 7509P)

Through: Nancy Dodd, Chemist

Mohsen Sahafeyan, Chemist

Dietary Exposure Science Advisory Council (DESAC)

and

George F. Kramer, Ph.D., Branch Senior Chemist

RAB1/HED (7509P)

To: Barbara Madden RM05

Registration Division (RD; 7505P)

and

Kelly Lowe, Risk Assessor

RAB1/HED (7509P)

NOTE: This document supersedes Memo, W. Wassell, 03-APR-2009 (D362644) and Memo, J. 

Van Alstine, 18-AUG-2010 (D364912). This assessment has been updated to include revisions 

to the acute reference dose for females 13-49 years old. 
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

PC Code: 129081

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Executive Summary

Acute and chronic aggregate dietary (food and drinking water) exposure and risk assessments 

were conducted using the Dietary Exposure Evaluation Model - Food Consumption Intake 

Database (DEEM-FCID, ver. 2.03). DEEM-FCIDincorporates food consumption data from 

the United States Department of Agriculture (USDA) Continuing Surveys of Food Intakes by

Individuals (CSFII; 1994-1996 and 1998). The revised assessment is being conducted in support 

of new uses on Brassica, head and stem, subgroup 5A; Brassica, leafy greens, subgroup 5B; 

melon subgroup 9A; fruiting vegetable, group 8 and okra; pea, succulent; flax; strawberry; 

tuberous and corm vegetable, subgroup 1C; and miscellaneous fruiting vegetables; and changes 

to the toxicological doses and endpoints for sulfentrazone. 

Acute Dietary (Food and Drinking Water) Exposure Results and Characterization

The acute analysis assumed tolerance-level residues for all commodities, 100% crop treated 

(%CT), and DEEM(ver. 7.81) default processing factors (as necessary). The acute analysis 

also incorporated the drinking water estimates provided by the Environmental Fate and Effects 

Division (EFED). The resulting acute food plus water risk estimates are below HED’s level of 

concern [<100% of the acute population-adjusted dose (aPAD)] at the 95th percentile of the 

exposure distribution for the U.S. general population (less than 1% aPAD), and all population 

subgroups. The aPAD is lower for females 13 to 49 years old. The population subgroup with 

the greatest risk was females 13 to 49 years old which utilized less than 3% of the aPAD. 

Chronic Dietary (Food and Drinking Water) Exposure Results and Characterization 

The chronic analysis assumed tolerance-level residues, 100% CT, and DEEM(ver. 7.81) 

default processing factors (as necessary) for all commodities. The chronic analysis also 

incorporated the drinking water estimates provided by EFED. The resulting chronic risk 

estimates are below HED’s level of concern. The most highly exposed population subgroup was

children 1-2 years old, which utilized less than 4% of the chronic PAD (cPAD).

Cancer Dietary (Food and Drinking Water) Exposure Results and Characterization

A cancer dietary assessment was not conducted because sulfentrazone is classified as “not likely

to be carcinogenic to humans.”

I. Introduction

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide. For acute 

and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose 

(i.e., the dose which HED has concluded will result in no unreasonable adverse health effects). 

This dose is referred to as the PAD. The PAD is equivalent to a point-of-departure [POD; e.g., 

no-observable-adverse-effect-level (NOAEL)] divided by the required uncertainty or safety 

factors. For acute and non-cancer chronic exposures, HED is concerned when estimated dietary

risk exceeds 100% of the PAD. References which discuss the acute and chronic risk assessments 
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

PC Code: 129081

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in more detail are available on the EPA/pesticides web site: “Available Information on 

Assessing Exposure from Pesticides, A User’s Guide,” 6/21/2000, web link: 

http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf; or see SOP 99.6 (8/20/99). 

The most recent sulfentrazone dietary exposure assessment was conducted by J. Van Alstine (18-

AUG-2010; D364912).

II. Residue Information

Residues of Concern in Plants and Livestock: The HED Metabolism Assessment Review 

Committee (MARC) has determined that the parent compound, sulfentrazone, and the metabolite 

HMS [N-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-hydroxymethyl-5-oxo-1H-1,2,4-

triazol-yl)phenyl)methanesulfonamide)] are the residues of concern in soybeans, and that 

sulfentrazone and its metabolites HMS and DMS [(N-2,4- dichloro-5-[4-(difluoromethyl)-4,5-

dihydro-5-oxo-1H-1,2,4-triazol-1-yl)phenyl)methanesulfonamide] are the residues of concern in 

rotational crops (Memo, G. Kramer, 14-JUN-1996; D226434). HED has concluded that the 

results of the rotational crop metabolism studies may be translated to support preemergent uses 

on all types of crops. Additionally, sulfentrazone and its metabolites HMS and DMS were 

identified as the residues of concern in meat, milk, poultry, and eggs. The HED MARC

recommended that parent and 3-carboxylic acid sulfentrazone are the residues of concern for the 

drinking-water assessment (Memo, G. Kramer et al., 10-APR-2003; D288713). HED continues 

to consider the given metabolites and degradates to be the residues of concern for risk 

assessment. 

Established/Recommended Tolerances: A tolerance is currently established under 40 CFR 

§180.498(a)(1) for the combined residues of sulfentrazone and its major metabolite, HMS, in/on 

soybean seed at 0.05 ppm. In addition, permanent tolerances are established under 40 CFR 

§180.498(a)(2) for the combined residues of sulfentrazone and its metabolites HMS and DMS 

in/on several food commodities; these established tolerances range from 0.15 ppm (various plant 

commodities) to 0.40 ppm (peanut meal). Time-limited tolerances for the combined residues of 

sulfentrazone and its metabolites HMS and DMS have been established under 40 CFR 

§180.498(b) in connection with Section 18 Emergency Exemptions; these include tolerances for 

residues in/on bean, succulent-seed without pod (lima bean and cowpea) at 0.1 ppm with a 

12/31/07 expiration date, flax seed at 0.20 ppm with a 12/31/10 expiration date, and strawberry

at 0.60 ppm with a 12/31/10 expiration date. Finally, tolerances are established under 40 CFR 

§180.498(d) for inadvertent and indirect combined residues of sulfentrazone and its metabolites 

HMS and DMS in/on cereal grain (excluding sweet corn) bran, forage, grain, hay, hulls, stover, 

and straw at 0.1-0.6 ppm as a result of the application of sulfentrazone to growing crops.

The proposed uses and the submitted data support the establishment of the following tolerances 

for the combined residues of sulfentrazone and its metabolites HMS and DMS in/on:

Brassica, head and stem, subgroup 5A.......................0.20 ppm

Brassica, leafy greens, subgroup 5B...........................0.40 ppm

Melon subgroup 9A ....................................................0.15 ppm

Vegetable, fruiting, group 8........................................0.15 ppm

Okra.............................................................................0.15 ppm
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

PC Code: 129081

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Pea, succulent..............................................................0.15 ppm

Flax .............................................................................0.15 ppm

Strawberry...................................................................0.15 ppm

Vegetable, tuberous and corm, subgroup 1C..............0.15 ppm

Cocona ........................................................................0.15 ppm

Eggplant, African........................................................0.15 ppm

Eggplant, pea...............................................................0.15 ppm

Eggplant, scarlet..........................................................0.15 ppm

Goji berry....................................................................0.15 ppm

Huckleberry, garden....................................................0.15 ppm

Martynia......................................................................0.15 ppm

Naranjilla.....................................................................0.15 ppm

Roselle.........................................................................0.15 ppm

Sunberry......................................................................0.15 ppm

Tomato, bush...............................................................0.15 ppm

Tomato, currant...........................................................0.15 ppm

Tomato, tree ................................................................0.15 ppm

Residues used in the Acute and Chronic Analyses: These analyses employed tolerance-level 

residues for all commodities, 100% CT, and DEEM(ver. 7.81) default processing factors. The 

following fruiting vegetables are not listed in DEEM-FCIDand were therefore not included in the 

chronic assessment: cocona, African eggplant, pea eggplant, scarlet eggplant, goji berry, garden 

huckleberry, martynia, naranjilla, roselle, sunberry, bush tomato, and currant tomato. However, 

tree tomato is included in DEEMand was therefore included in the acute and chronic 

assessments.

III. Estimated Drinking Water Concentrations

Drinking water residues were incorporated directly into the acute and chronic dietary analyses 

(“water, direct, all sources” and “water, indirect, all sources”) and were provided by EFED 

(Memo, 9/15/2009, L. Liu, D366552). The estimated drinking water concentrations (EDWCs) 

were Tier 1 estimates for ground water using the SCI-GROW Model (Screening Concentration 

In Ground Water) and surface water using the FIRST Model [Food Quality Protection Act 

(FQPA) Index Reservoir Screening Tool] for sulfentrazone and its major degradate, 3-carboxylic 

acid sulfentrazone. The EDWCs were based on the use of sulfentrazone on sugarcane, cabbage,

potatoes, mint, or horseradish.

For surface water, the acute (peak) sulfentrazone value is 32.0 ppb and the annual average value 

ranges from 0.5 ppb in alkaline or neutral waters (most common) to 5.1 ppb in acidic waters. 

The groundwater screening sulfentrazone concentration is 15.7 ppb. For 3-carboxylic acid 

sulfentrazone, the acute peak is 3.8 ppb and the annual average is 2.7 ppb. For 3-carboxylic acid 

sulfentrazone in groundwater, the concentration is 10.3 ppb. These values generally represent 

upper-bound conservative estimates of the total residue concentrations that might be found in 

surface water and groundwater due to the use of sulfentrazone on sugarcane, cabbage, potatoes, 

mint, or horseradish. These crops were chosen for this assessment because the label permits use 

of the maximum application rate (0.375 lb ai/A) and aerial application. Aerial application has 

the potential for most spray drift and is not compatible with incorporation which would reduce 
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

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surface water concentration values. EDWCs of 0.0358 ppm and 0.026 ppm were used in the 

acute and chronic analyses, respectively.

Table 1. Estimated Tier 1 Concentrations of Sulfentrazone and 3-Carboxylic Acid Sulfentrazone in 

Drinking Water Due to the Use of Sulfentrazone on Sugarcane, Cabbage, Potatoes, Mint, or Horseradish1.

Chemical Surface Water (ug/L) Groundwater (ug/L)

Acute Chronic Acute and Chronic

Sulfentrazone 32.0 5.1 15.7

3-Carboxylic Acid Sulfentrazone 3.8 2.7 10.3

Total 35.8 7.8 26.0

1 These crops were chosen for this assessment because the label permits use of the maximum application rate (0.375 pounds 

active ingredient per acre) and aerial application.

IV. DEEM-FCIDProgram and Consumption Information

Sulfentrazone acute and chronic dietary exposure and risk assessments were conducted using 

DEEM-FCID(Ver. 2.03), which incorporates consumption data from USDA’s CSFII, (1994-

1996 and 1998 data). The 1994-1996, 1998 data are based on the reported consumption of more 

than 20,000 individuals over two non-consecutive survey days. Foods “as consumed” (e.g., 

apple pie) are linked to EPA-defined food commodities (e.g., apples, peeled fruit - cooked; fresh 

or N/S; baked; or wheat flour - cooked; fresh or N/S, baked) using publicly available recipe 

translation files developed jointly by USDA/ARS and EPA. For chronic exposure assessment, 

consumption data are averaged for the entire U.S. population and within population subgroups, 

but for acute exposure assessment are retained as individual consumption events. Based on 

analysis of the 1994-96, 98 CSFII consumption data, which took into account dietary patterns 

and survey respondents, HED concluded that it is most appropriate to report risk for the 

following population subgroups: the general U.S. population, all infants (<1 year old), children 

1-2 years old, children 3-5 years old, children 6-12 years old, youth 13-19 years old, adults 20-49

years old, females 13-49 years old, and adults 50+ years old.

For chronic dietary exposure assessment, an estimate of the residue level in each food or foodform (e.g., orange or orange juice) on the food commodity residue list is multiplied by the 

average daily consumption estimate for that food/food form to produce a residue intake estimate. 

The resulting residue intake estimate for each food/food form is summed with the residue intake 

estimates for all other food/food forms on the commodity residue list to arrive at the total 

average estimated exposure. Exposure is expressed in mg/kg body weight/day and as a percent 

of the cPAD. This procedure is performed for each population subgroup.

For acute exposure assessments, individual one-day food consumption data are used on an 

individual-by-individual basis. The reported consumption amounts of each food item can be 

multiplied by a residue point estimate and summed to obtain a total daily pesticide exposure for a 

deterministic exposure assessment, or “matched” in multiple random pairings with residue values 

and then summed in a probabilistic assessment. The resulting distribution of exposures is expressed 

as a percentage of the aPAD on both a user (i.e., only those who reported eating relevant 

commodities/food forms) and a per-capita (i.e., those who reported eating the relevant commodities 
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

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as well as those who did not) basis. In accordance with HED policy, per capita exposure and risk are 

reported for all tiers of analysis. However, for Tiers 1 and 2, any significant differences in user vs. 

per capita exposure and risk are specifically identified and noted in the risk assessment.

V. Toxicological Information

The RAB1 toxicologists have reevaluated the sulfentrazone database and updated the endpoints 

as necessary. The toxicological endpoints selected for sulfentrazone are summarized below in 

Table 2.

Table 2. Summary of Toxicological Doses and Endpoints for Sulfentrazone for Use in Human-Health Risk 

Assessments.

Exposure

Scenario

Point of 

Departure

Uncertainty/

FQPA Safety 

Factors

RfD, PAD, 

Level of 

Concern for 

Risk 

Assessment

Study and Relevant Toxicological Effects

Acute Dietary

(Females 13-

49)

NOAEL = 

14 

mg/kg/day

UFA = 10X

UFH = 10X

FQPA SF = 

1X

aRfD = aPAD = 

0.14 mg/kg/day

2-Gen Reproductive Toxicity Study - Rat

Offspring Toxicity LOAEL= 33 (M) and 40 

(F) mg/kg/day based on reduced prenatal 

viability (fetal & litter), reduced litter size, 

increased no. of stillborn pups, reduced pup 

and litter postnatal survival and decreased pup 

body weights throughout lactation.

Acute Dietary

(General 

population

including 

infants

and children)

NOAEL = 

250 

mg/kg/day

UFA = 10X

UFH = 10X

FQPA SF = 

1X

aRfD =aPAD = 

2.5 mg/kg/day

Acute-Neurotoxicity Study - Rat

LOAEL = 750 mg/kg/day based on increased 

incidence of clinical signs and FOB 

parameters and decreased motor activity.

Chronic 

Dietary

(all 

populations)

NOAEL= 

10 

mg/kg/day 

UFA = 10X

UFH = 10X

FQPA SF = 

1X

cRfD = cPAD =

0.10 mg/kg/day

Prenatal Developmental Toxicity - Rat

Developmental LOAEL = 25 mg/kg/day, 

based upon decreased mean fetal weights, and 

retardation in skeletal development evidenced 

by an increased number of litters with any 

variation and by decreased number of caudal 

vertebral and metacarpal ossification sites.

Cancer (oral, 

dermal, 

inhalation)

Classification: sulfentrazone is classified as “not likely to be carcinogenic to humans.”

NOAEL = no-observed adverse-effect level. LOAEL = lowest-observed adverse-effect level. UF = uncertainty factor. UFA = 

extrapolation from animal to human (interspecies). UFH = potential variation in sensitivity among members of the human 

population (intraspecies). UFL = extrapolation for use of a LOAEL in the absence of a NOAEL. FQPA SF = FQPA Safety 

Factor. PAD = population-adjusted dose (a = acute, c = chronic). RfD = reference dose. MOE = margin of exposure, LOC = 

level of concern.

VI. Results/Discussion

Acute and chronic analyses were performed using DEEM-FCID(ver. 2.03). DEEM-FCID

estimates the dietary exposure and risk of the U.S. population and various population subgroups. 

The results reported are for the general U.S. Population, all infants (<1 year old), children 1-2
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

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years old, children 3-5 years old, children 6-12 years old, youth 13-19 years old, females 13-49

years old, adults 20-49 years old, and adults 50+ years old. 

The resulting acute food plus water risk estimates are below HED’s level of concern (<100% 

aPAD) at the 95th percentile of the exposure distribution for the general U.S. population (less 

than 1% aPAD), and all population subgroups; the population subgroup with the greatest risk 

was females 13 to 49 years, which utilized less than 3% of the aPAD. See Table 3 below for a 

summary of the results of the acute assessment. The resulting chronic risk estimates are also 

below HED’s level of concern. The most highly exposed population was children 1-2 years old

which utilized less than 4% of the cPAD. See Table 4 below for a summary of the results of the 

chronic assessment.

Table 3. Summary of Acute Dietary Exposure and Risk for Sulfentrazone at the 95th Percentile.1

Population Subgroup aPAD (mg/kg/day) Exposure (mg/kg/day) %aPAD

General U.S. Population

2.5

0.004347 <1.0

All Infants (< 1 year old) 0.009388 <1.0

Children 1-2 years old 0.008187 <1.0

Children 3-5 years old 0.007476 <1.0

Children 6-12 years old 0.005284 <1.0

Youth 13-19 years old 0.003695 <1.0

Adults 20-49 years old 0.003341 <1.0

Adults 50+ years old 0.002942 <1.0

Females 13-49 years old 0.14 0.003256 2.3

1 The population with the greatest risk is bolded.

Table 4. Summary of Chronic Dietary Exposure and Risk for Sulfentrazone.

1

Population Subgroup cPAD (mg/kg/day) Exposure (mg/kg/day) %cPAD

General U.S. Population

0.10

0.001751 1.8

All Infants (< 1 year old) 0.003117 3.1

Children 1-2 years old 0.003565 3.6

Children 3-5 years old 0.003463 3.5

Children 6-12 years old 0.002404 2.4

Youth 13-19 years old 0.001660 1.7

Adults 20-49 years old 0.001492 1.5

Adults 50+ years old 0.001360 1.4

Females 13-49 years old 0.001451 1.5

1 The population with the greatest risk is bolded.

VII. Characterization of Inputs/Outputs

The unrefined acute and chronic analyses assumed tolerance-level residues for all commodities, 

100% CT, and DEEM(ver. 7.81) default processing factors (as necessary). These analyses are 

considered conservative and could be refined through the use of anticipated-residue estimates 
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

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(ARs) for all commodities, %CT data for registered commodities, and empirical processing 

factors.

VIII. Conclusions

The acute and chronic dietary exposure and risk estimates for sulfentrazone are below HED’s 

level of concern. For food and drinking water acute exposure, the population subgroup with the 

greatest risk was females 13 to 49 years old, which utilized less than 3% of the aPAD. 

For food and drinking water chronic exposure, the most highly-exposed population subgroup 

was children 1-2 years old, which utilized less than 4% of the cPAD. The acute and chronic 

dietary exposure assessments support the new uses proposed for sulfentrazone.

Attachments

Attachment 1: DEEM-FCID

 Acute Residue File.

Attachment 2: DEEM-FCID

 Acute Exposure Estimates for the General Population Including Infants and 

Children. 

Attachment 3: DEEM-FCID

 Chronic Residue File.

Attachment 4: DEEM-FCID

 Chronic Exposure Estimates.

RDI: DE SAC Reviewers: 19-NOV-2010; G. Kramer 17-NOV-2010

DP No.: D384090

Petition No.: 7E7308 

PC Code: 129081

J. L. Van Alstine:S-10951:Potomac Yard:703-603-8866:7509P:RAB1
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

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Attachment 1: DEEM-FCID Acute Residue File.

Filename: C:\Documents and Settings\jlangsda\My Documents\Chemicals\Sulfentrazone\November 2010\Sent 

to Reviewers\129081-acute-2009-jml__01 DEC 2010.R98

Chemical: Sulfentrazone

RfD(Chronic): .1 mg/kg bw/day NOEL(Chronic): 0 mg/kg bw/day

RfD(Acute): 2.5 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/day

Date created/last modified: 12-01-2010/09:50:36/8 Program ver. 2.03

--------------------------------------------------------------------------------

 EPA Crop Def Res Adj.Factors Comment

 Code Grp Commodity Name (ppm) #1 #2 

-------- ---- ------------------------------- ---------- ------ ------ -------

01011900 1AB Horseradish 0.200000 1.000 1.000 1E0631

 Full comment: 1E06311; TLT 0.10 ppm, exp. 12/31/05

01030150 1CD Arrowroot, flour 0.150000 1.000 1.000 

01030151 1CD Arrowroot, flour-babyfood 0.150000 1.000 1.000 

01030170 1CD Artichoke, Jerusalem 0.150000 1.000 1.000 

01030820 1CD Cassava 0.150000 1.000 1.000 

01030821 1CD Cassava-babyfood 0.150000 1.000 1.000 

01031390 1CD Dasheen, corm 0.150000 1.000 1.000 

01031660 1CD Ginger 0.150000 1.000 1.000 

01031661 1CD Ginger-babyfood 0.150000 1.000 1.000 

01031670 1CD Ginger, dried 0.150000 1.000 1.000 

01032960 1C Potato, chips 0.150000 1.000 1.000 

01032970 1C Potato, dry (granules/ flakes) 0.150000 6.500 1.000 

01032971 1C Potato, dry (granules/ flakes)-b 0.150000 6.500 1.000 

01032980 1C Potato, flour 0.150000 6.500 1.000 

01032981 1C Potato, flour-babyfood 0.150000 6.500 1.000 

01032990 1C Potato, tuber, w/peel 0.150000 1.000 1.000 

01032991 1C Potato, tuber, w/peel-babyfood 0.150000 1.000 1.000 

01033000 1C Potato, tuber, w/o peel 0.150000 1.000 1.000 

01033001 1C Potato, tuber, w/o peel-babyfood 0.150000 1.000 1.000 

01033660 1CD Sweet potato 0.150000 1.000 1.000 

01033661 1CD Sweet potato-babyfood 0.150000 1.000 1.000 

01033710 1CD Tanier, corm 0.150000 1.000 1.000 

01033870 1CD Turmeric 0.150000 1.000 1.000 

01034060 1CD Yam, true 0.150000 1.000 1.000 

01034070 1CD Yam bean 0.150000 1.000 1.000 

05010610 5A Broccoli 0.200000 1.000 1.000 

05010611 5A Broccoli-babyfood 0.200000 1.000 1.000 

05010620 5A Broccoli, Chinese 0.200000 1.000 1.000 

05010640 5A Brussels sprouts 0.200000 1.000 1.000 

05010690 5A Cabbage 0.200000 1.000 1.000 1E0631

 Full comment: 1E06311

05010710 5A Cabbage, Chinese, napa 0.200000 1.000 1.000 1E0631

 Full comment: 1E06311

05010720 5A Cabbage, Chinese, mustard 0.200000 1.000 1.000 1E0631

 Full comment: 1E06311

05010830 5A Cauliflower 0.200000 1.000 1.000 

05011960 5A Kohlrabi 0.200000 1.000 1.000 

05020630 5B Broccoli raab 0.400000 1.000 1.000 

05020700 5B Cabbage, Chinese, bok choy 0.400000 1.000 1.000 1E0631

 Full comment: 1E06311

05021170 5B Collards 0.400000 1.000 1.000 

05021940 5B Kale 0.400000 1.000 1.000 

05022290 5B Mustard greens 0.400000 1.000 1.000 

05023180 5B Rape greens 0.400000 1.000 1.000 

05023890 5B Turnip, greens 0.400000 1.000 1.000 

06003470 6 Soybean, seed 0.050000 1.000 1.000 

06003480 6 Soybean, flour 0.050000 1.000 1.000 

06003481 6 Soybean, flour-babyfood 0.050000 1.000 1.000 

06003490 6 Soybean, soy milk 0.050000 1.000 1.000 

06003491 6 Soybean, soy milk-babyfood or in 0.050000 1.000 1.000 

06003500 6 Soybean, oil 0.050000 1.000 1.000 

06003501 6 Soybean, oil-babyfood 0.050000 1.000 1.000 

06010430 6A Bean, snap, succulent 0.150000 1.000 1.000 

06010431 6A Bean, snap, succulent-babyfood 0.150000 1.000 1.000 

06012570 6A Pea, edible podded, succulent 0.150000 1.000 1.000 

06020310 6B Bean, broad, succulent 0.150000 1.000 1.000 

06020330 6B Bean, cowpea, succulent 0.100000 1.000 1.000 TLT, e
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 Full comment: TLT, exp. 12/31/04

06020370 6B Bean, lima, succulent 0.150000 1.000 1.000 

06022550 6B Pea, succulent 0.150000 1.000 1.000 

06022551 6B Pea, succulent-babyfood 0.150000 1.000 1.000 

06022590 6B Pea, pigeon, succulent 0.150000 1.000 1.000 

06030300 6C Bean, black, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030320 6C Bean, broad, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030340 6C Bean, cowpea, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030350 6C Bean, great northern, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030360 6C Bean, kidney, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030380 6C Bean, lima, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030390 6C Bean, mung, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030400 6C Bean, navy, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030410 6C Bean, pink, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030420 6C Bean, pinto, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030980 6C Chickpea, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030981 6C Chickpea, seed-babyfood 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030990 6C Chickpea, flour 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06031820 6C Guar, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06031821 6C Guar, seed-babyfood 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06032030 6C Lentil, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06032560 6C Pea, dry 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06032561 6C Pea, dry-babyfood 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06032580 6C Pea, pigeon, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

08001480 8 Eggplant 0.150000 1.000 1.000 

08002340 8 Okra 0.150000 1.000 1.000 

08002700 8 Pepper, bell 0.150000 1.000 1.000 

08002701 8 Pepper, bell-babyfood 0.150000 1.000 1.000 

08002710 8 Pepper, bell, dried 0.150000 1.000 1.000 

08002711 8 Pepper, bell, dried-babyfood 0.150000 1.000 1.000 

08002720 8 Pepper, nonbell 0.150000 1.000 1.000 New, S

 Full comment: New, Section 18

08002721 8 Pepper, nonbell-babyfood 0.150000 1.000 1.000 New, S

 Full comment: New, Section 18

08002730 8 Pepper, nonbell, dried 0.150000 1.000 1.000 New, S

 Full comment: New, Section 18

08003740 8 Tomatillo 0.150000 1.000 1.000 

08003750 8 Tomato 0.150000 1.000 1.000 

08003751 8 Tomato-babyfood 0.150000 1.000 1.000 

08003760 8 Tomato, paste 0.150000 5.400 1.000 

08003761 8 Tomato, paste-babyfood 0.150000 5.400 1.000 

08003770 8 Tomato, puree 0.150000 3.300 1.000 

08003771 8 Tomato, puree-babyfood 0.150000 3.300 1.000 

08003780 8 Tomato, dried 0.150000 14.300 1.000 

08003781 8 Tomato, dried-babyfood 0.150000 14.300 1.000 

08003790 8 Tomato, juice 0.150000 1.500 1.000 

09010750 9A Cantaloupe 0.150000 1.000 1.000 

09010800 9A Casaba 0.150000 1.000 1.000 

09011870 9A Honeydew melon 0.150000 1.000 1.000 

09013990 9A Watermelon 0.150000 1.000 1.000 

09014000 9A Watermelon, juice 0.150000 1.000 1.000 

15000250 15 Barley, pearled barley 0.100000 1.000 1.000 Inadve
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

PC Code: 129081

____________________________________________________________________________________________

Page 11 of 18

 Full comment: Inadvertent tol.

15000251 15 Barley, pearled barley-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15000260 15 Barley, flour 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15000261 15 Barley, flour-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15000270 15 Barley, bran 0.150000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15000650 15 Buckwheat 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15000660 15 Buckwheat, flour 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15001200 15 Corn, field, flour 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001201 15 Corn, field, flour-babyfood 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001210 15 Corn, field, meal 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001211 15 Corn, field, meal-babyfood 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001220 15 Corn, field, bran 0.150000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15001230 15 Corn, field, starch 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001231 15 Corn, field, starch-babyfood 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001240 15 Corn, field, syrup 0.150000 1.500 1.000 2F0639

 Full comment: 2F06391

15001241 15 Corn, field, syrup-babyfood 0.150000 1.500 1.000 2F0639

 Full comment: 2F06391

15001250 15 Corn, field, oil 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001251 15 Corn, field, oil-babyfood 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001260 15 Corn, pop 0.100000 1.000 1.000 2F0639

 Full comment: 2F06391

15002260 15 Millet, grain 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15002310 15 Oat, bran 0.150000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15002320 15 Oat, flour 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15002321 15 Oat, flour-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15002330 15 Oat, groats/rolled oats 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15002331 15 Oat, groats/rolled oats-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003230 15 Rice, white 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003231 15 Rice, white-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003240 15 Rice, brown 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003241 15 Rice, brown-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003250 15 Rice, flour 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003251 15 Rice, flour-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003260 15 Rice, bran 0.150000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003261 15 Rice, bran-babyfood 0.150000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003280 15 Rye, grain 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003290 15 Rye, flour 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003440 15 Sorghum, grain 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

PC Code: 129081

____________________________________________________________________________________________

Page 12 of 18

15003450 15 Sorghum, syrup 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003810 15 Triticale, flour 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003811 15 Triticale, flour-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15004010 15 Wheat, grain 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15004011 15 Wheat, grain-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15004020 15 Wheat, flour 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15004021 15 Wheat, flour-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15004030 15 Wheat, germ 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15004040 15 Wheat, bran 0.150000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15004050 15 Wild rice 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

20001630 20 Flaxseed, oil 0.150000 1.000 1.000 

20003640 20 Sunflower, seed 0.200000 1.000 1.000 

20003650 20 Sunflower, oil 0.200000 1.000 1.000 

20003651 20 Sunflower, oil-babyfood 0.200000 1.000 1.000 

86010000 O Water, direct, all sources 0.035800 1.000 1.000 

86020000 O Water, indirect, all sources 0.035800 1.000 1.000 

95000190 O Asparagus 0.150000 1.000 1.000 2E0650

 Full comment: 2E06500

95002630 O Peanut 0.200000 1.000 1.000 0F0611

 Full comment: 0F06116

95002640 O Peanut, butter 0.200000 1.890 1.000 0F0611

 Full comment: 0F06116

95002650 O Peanut, oil 0.200000 1.000 1.000 0F0611

 Full comment: 0F06116

95002750 O Peppermint 0.300000 1.000 1.000 1E0631

 Full comment: 1E06311

95002760 O Peppermint, oil 0.300000 1.000 1.000 1E0631

 Full comment: 1E06311

95003520 O Spearmint 0.300000 1.000 1.000 1E0631

 Full comment: 1E06311

95003530 O Spearmint, oil 0.300000 1.000 1.000 1E0631

 Full comment: 1E06311

95003590 O Strawberry 0.150000 1.000 1.000 

95003591 O Strawberry-babyfood 0.150000 1.000 1.000 

95003600 O Strawberry, juice 0.150000 1.000 1.000 

95003601 O Strawberry, juice-babyfood 0.150000 1.000 1.000 

95003620 O Sugarcane, sugar 0.150000 1.000 1.000 

95003621 O Sugarcane, sugar-babyfood 0.150000 1.000 1.000 

95003630 O Sugarcane, molasses 0.200000 1.000 1.000 

95003631 O Sugarcane, molasses-babyfood 0.200000 1.000 1.000 

95003800 O Tomato, Tree 0.150000 1.000 1.000 
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

PC Code: 129081

____________________________________________________________________________________________

Page 13 of 18

Attachment 2: DEEM-FCID Acute Exposure Estimates for the General Population including 

Infants and Children.

1

U.S. Environmental Protection Agency Ver. 2.02

DEEM-FCID ACUTE Analysis for SULFENTRAZONE (1994-98 data)

Residue file: 129081-acute-2009-jml__01 DEC 2010.R98

 Adjustment factor #2 used.

Analysis Date: 12-01-2010/09:52:09 Residue file dated: 12-01-2010/09:50:36/8

Daily totals for food and foodform consumption used.

Run Comment: ""

===============================================================================

Summary calculations (per capita):

 95th Percentile 99th Percentile 99.9th Percentile

 Exposure % aRfD Exposure % aRfD Exposure % aRfD 

 ---------- -------- ---------- -------- ---------- --------

U.S. Population:

 0.004347 0.17 0.007110 0.28 0.011882 0.48 

All infants:

 0.009388 0.38 0.013235 0.53 0.020709 0.83 

Children 1-2 yrs:

 0.008187 0.33 0.011436 0.46 0.018298 0.73 

Children 3-5 yrs:

 0.007476 0.30 0.010856 0.43 0.017357 0.69 

Children 6-12 yrs:

 0.005284 0.21 0.007704 0.31 0.010870 0.43 

Youth 13-19 yrs:

 0.003695 0.15 0.005772 0.23 0.010982 0.44 

Adults 20-49 yrs:

 0.003341 0.13 0.004837 0.19 0.008144 0.33 

Adults 50+ yrs:

 0.002942 0.12 0.004081 0.16 0.006160 0.25 

Females 13-49 yrs:

 0.003256 0.132 0.004506 0.18 0.007684 0.31 

1 The aPAD for the general population including infants and children = 2.5 mg/kg bw/day. The aPAD for females 13-49 years 

old = 0.14 mg/kg bw/day.

2 This value was calculated by DEEMTM using an aPAD of 2.5 mg/kg bw/day. The % aPAD reported in Table 3 was adjusted to 

account for the lower aPAD (0.14 mg/kg bw/day) for females 13-49 years old using the following formula: % aPAD = 

(Exposure/aPAD)*100% = (0.003256/0.14)*100% = 2.3%.
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

PC Code: 129081

____________________________________________________________________________________________

Page 14 of 18

Attachment 3: DEEM-FCID Chronic Residue File.

Filename: C:\Documents and Settings\jlangsda\My Documents\Chemicals\Sulfentrazone\November 2010\Sent 

to Reviewers\129081-chronic-2009-jml__01 DEC 2010.R98

Chemical: Sulfentrazone

RfD(Chronic): .1 mg/kg bw/day NOEL(Chronic): 0 mg/kg bw/day

RfD(Acute): 2.5 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/day

Date created/last modified: 12-01-2010/09:51:00/8 Program ver. 2.03

--------------------------------------------------------------------------------

 EPA Crop Def Res Adj.Factors Comment

 Code Grp Commodity Name (ppm) #1 #2 

-------- ---- ------------------------------- ---------- ------ ------ -------

01011900 1AB Horseradish 0.200000 1.000 1.000 1E0631

 Full comment: 1E06311; TLT 0.10 ppm, exp. 12/31/05

01030150 1CD Arrowroot, flour 0.150000 1.000 1.000 

01030151 1CD Arrowroot, flour-babyfood 0.150000 1.000 1.000 

01030170 1CD Artichoke, Jerusalem 0.150000 1.000 1.000 

01030820 1CD Cassava 0.150000 1.000 1.000 

01030821 1CD Cassava-babyfood 0.150000 1.000 1.000 

01031390 1CD Dasheen, corm 0.150000 1.000 1.000 

01031660 1CD Ginger 0.150000 1.000 1.000 

01031661 1CD Ginger-babyfood 0.150000 1.000 1.000 

01031670 1CD Ginger, dried 0.150000 1.000 1.000 

01032960 1C Potato, chips 0.150000 1.000 1.000 

01032970 1C Potato, dry (granules/ flakes) 0.150000 6.500 1.000 

01032971 1C Potato, dry (granules/ flakes)-b 0.150000 6.500 1.000 

01032980 1C Potato, flour 0.150000 6.500 1.000 

01032981 1C Potato, flour-babyfood 0.150000 6.500 1.000 

01032990 1C Potato, tuber, w/peel 0.150000 1.000 1.000 

01032991 1C Potato, tuber, w/peel-babyfood 0.150000 1.000 1.000 

01033000 1C Potato, tuber, w/o peel 0.150000 1.000 1.000 

01033001 1C Potato, tuber, w/o peel-babyfood 0.150000 1.000 1.000 

01033660 1CD Sweet potato 0.150000 1.000 1.000 

01033661 1CD Sweet potato-babyfood 0.150000 1.000 1.000 

01033710 1CD Tanier, corm 0.150000 1.000 1.000 

01033870 1CD Turmeric 0.150000 1.000 1.000 

01034060 1CD Yam, true 0.150000 1.000 1.000 

01034070 1CD Yam bean 0.150000 1.000 1.000 

05010610 5A Broccoli 0.200000 1.000 1.000 

05010611 5A Broccoli-babyfood 0.200000 1.000 1.000 

05010620 5A Broccoli, Chinese 0.200000 1.000 1.000 

05010640 5A Brussels sprouts 0.200000 1.000 1.000 

05010690 5A Cabbage 0.200000 1.000 1.000 1E0631

 Full comment: 1E06311

05010710 5A Cabbage, Chinese, napa 0.200000 1.000 1.000 1E0631

 Full comment: 1E06311

05010720 5A Cabbage, Chinese, mustard 0.200000 1.000 1.000 1E0631

 Full comment: 1E06311

05010830 5A Cauliflower 0.200000 1.000 1.000 

05011960 5A Kohlrabi 0.200000 1.000 1.000 

05020630 5B Broccoli raab 0.400000 1.000 1.000 

05020700 5B Cabbage, Chinese, bok choy 0.400000 1.000 1.000 1E0631

 Full comment: 1E06311

05021170 5B Collards 0.400000 1.000 1.000 

05021940 5B Kale 0.400000 1.000 1.000 

05022290 5B Mustard greens 0.400000 1.000 1.000 

05023180 5B Rape greens 0.400000 1.000 1.000 

05023890 5B Turnip, greens 0.400000 1.000 1.000 

06003470 6 Soybean, seed 0.050000 1.000 1.000 

06003480 6 Soybean, flour 0.050000 1.000 1.000 

06003481 6 Soybean, flour-babyfood 0.050000 1.000 1.000 

06003490 6 Soybean, soy milk 0.050000 1.000 1.000 

06003491 6 Soybean, soy milk-babyfood or in 0.050000 1.000 1.000 

06003500 6 Soybean, oil 0.050000 1.000 1.000 

06003501 6 Soybean, oil-babyfood 0.050000 1.000 1.000 

06010430 6A Bean, snap, succulent 0.150000 1.000 1.000 

06010431 6A Bean, snap, succulent-babyfood 0.150000 1.000 1.000 

06012570 6A Pea, edible podded, succulent 0.150000 1.000 1.000 

06020310 6B Bean, broad, succulent 0.150000 1.000 1.000 

06020330 6B Bean, cowpea, succulent 0.100000 1.000 1.000 TLT, e

 Full comment: TLT, exp. 12/31/04
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

PC Code: 129081

____________________________________________________________________________________________

Page 15 of 18

06020370 6B Bean, lima, succulent 0.150000 1.000 1.000 2E0649

 Full comment: 2E06498

06022550 6B Pea, succulent 0.150000 1.000 1.000 

06022551 6B Pea, succulent-babyfood 0.150000 1.000 1.000 

06022590 6B Pea, pigeon, succulent 0.150000 1.000 1.000 

06030300 6C Bean, black, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030320 6C Bean, broad, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030340 6C Bean, cowpea, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030350 6C Bean, great northern, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030360 6C Bean, kidney, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030380 6C Bean, lima, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030390 6C Bean, mung, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030400 6C Bean, navy, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030410 6C Bean, pink, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030420 6C Bean, pinto, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030980 6C Chickpea, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030981 6C Chickpea, seed-babyfood 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06030990 6C Chickpea, flour 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06031820 6C Guar, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06031821 6C Guar, seed-babyfood 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06032030 6C Lentil, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06032560 6C Pea, dry 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06032561 6C Pea, dry-babyfood 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

06032580 6C Pea, pigeon, seed 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

08001480 8 Eggplant 0.150000 1.000 1.000 

08002340 8 Okra 0.150000 1.000 1.000 

08002700 8 Pepper, bell 0.150000 1.000 1.000 

08002701 8 Pepper, bell-babyfood 0.150000 1.000 1.000 

08002710 8 Pepper, bell, dried 0.150000 1.000 1.000 

08002711 8 Pepper, bell, dried-babyfood 0.150000 1.000 1.000 

08002720 8 Pepper, nonbell 0.150000 1.000 1.000 New, S

 Full comment: New, Section 18

08002721 8 Pepper, nonbell-babyfood 0.150000 1.000 1.000 New, S

 Full comment: New, Section 18

08002730 8 Pepper, nonbell, dried 0.150000 1.000 1.000 New, S

 Full comment: New, Section 18

08003740 8 Tomatillo 0.150000 1.000 1.000 

08003750 8 Tomato 0.150000 1.000 1.000 

08003751 8 Tomato-babyfood 0.150000 1.000 1.000 

08003760 8 Tomato, paste 0.150000 5.400 1.000 

08003761 8 Tomato, paste-babyfood 0.150000 5.400 1.000 

08003770 8 Tomato, puree 0.150000 3.300 1.000 

08003771 8 Tomato, puree-babyfood 0.150000 3.300 1.000 

08003780 8 Tomato, dried 0.150000 14.300 1.000 

08003781 8 Tomato, dried-babyfood 0.150000 14.300 1.000 

08003790 8 Tomato, juice 0.150000 1.500 1.000 

09010750 9A Cantaloupe 0.150000 1.000 1.000 

09010800 9A Casaba 0.150000 1.000 1.000 

09011870 9A Honeydew melon 0.150000 1.000 1.000 

09013990 9A Watermelon 0.150000 1.000 1.000 

09014000 9A Watermelon, juice 0.150000 1.000 1.000 

15000250 15 Barley, pearled barley 0.100000 1.000 1.000 Inadve
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

PC Code: 129081

____________________________________________________________________________________________

Page 16 of 18

 Full comment: Inadvertent tol.

15000251 15 Barley, pearled barley-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15000260 15 Barley, flour 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15000261 15 Barley, flour-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15000270 15 Barley, bran 0.150000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15000650 15 Buckwheat 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15000660 15 Buckwheat, flour 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15001200 15 Corn, field, flour 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001201 15 Corn, field, flour-babyfood 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001210 15 Corn, field, meal 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001211 15 Corn, field, meal-babyfood 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001220 15 Corn, field, bran 0.150000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15001230 15 Corn, field, starch 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001231 15 Corn, field, starch-babyfood 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001240 15 Corn, field, syrup 0.150000 1.500 1.000 2F0639

 Full comment: 2F06391

15001241 15 Corn, field, syrup-babyfood 0.150000 1.500 1.000 2F0639

 Full comment: 2F06391

15001250 15 Corn, field, oil 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001251 15 Corn, field, oil-babyfood 0.150000 1.000 1.000 2F0639

 Full comment: 2F06391

15001260 15 Corn, pop 0.100000 1.000 1.000 2F0639

 Full comment: 2F06391

15002260 15 Millet, grain 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15002310 15 Oat, bran 0.150000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15002320 15 Oat, flour 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15002321 15 Oat, flour-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15002330 15 Oat, groats/rolled oats 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15002331 15 Oat, groats/rolled oats-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003230 15 Rice, white 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003231 15 Rice, white-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003240 15 Rice, brown 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003241 15 Rice, brown-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003250 15 Rice, flour 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003251 15 Rice, flour-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003260 15 Rice, bran 0.150000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003261 15 Rice, bran-babyfood 0.150000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003280 15 Rye, grain 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003290 15 Rye, flour 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003440 15 Sorghum, grain 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

PC Code: 129081

____________________________________________________________________________________________

Page 17 of 18

15003450 15 Sorghum, syrup 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003810 15 Triticale, flour 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15003811 15 Triticale, flour-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15004010 15 Wheat, grain 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15004011 15 Wheat, grain-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15004020 15 Wheat, flour 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15004021 15 Wheat, flour-babyfood 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15004030 15 Wheat, germ 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15004040 15 Wheat, bran 0.150000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

15004050 15 Wild rice 0.100000 1.000 1.000 Inadve

 Full comment: Inadvertent tol.

20001630 20 Flaxseed, oil 0.150000 1.000 1.000 

20003640 20 Sunflower, seed 0.200000 1.000 1.000 

20003650 20 Sunflower, oil 0.200000 1.000 1.000 

20003651 20 Sunflower, oil-babyfood 0.200000 1.000 1.000 

86010000 O Water, direct, all sources 0.026000 1.000 1.000 

86020000 O Water, indirect, all sources 0.026000 1.000 1.000 

95000190 O Asparagus 0.150000 1.000 1.000 2E0650

 Full comment: 2E06500

95002630 O Peanut 0.200000 1.000 1.000 0F0611

 Full comment: 0F06116

95002640 O Peanut, butter 0.200000 1.890 1.000 0F0611

 Full comment: 0F06116

95002650 O Peanut, oil 0.200000 1.000 1.000 0F0611

 Full comment: 0F06116

95002750 O Peppermint 0.300000 1.000 1.000 1E0631

 Full comment: 1E06311

95002760 O Peppermint, oil 0.300000 1.000 1.000 1E0631

 Full comment: 1E06311

95003520 O Spearmint 0.300000 1.000 1.000 1E0631

 Full comment: 1E06311

95003530 O Spearmint, oil 0.300000 1.000 1.000 1E0631

 Full comment: 1E06311

95003590 O Strawberry 0.150000 1.000 1.000 

95003591 O Strawberry-babyfood 0.150000 1.000 1.000 

95003600 O Strawberry, juice 0.150000 1.000 1.000 

95003601 O Strawberry, juice-babyfood 0.150000 1.000 1.000 

95003620 O Sugarcane, sugar 0.150000 1.000 1.000 

95003621 O Sugarcane, sugar-babyfood 0.150000 1.000 1.000 

95003630 O Sugarcane, molasses 0.200000 1.000 1.000 

95003631 O Sugarcane, molasses-babyfood 0.200000 1.000 1.000 

95003800 O Tomato, Tree 0.150000 1.000 1.000 
Sulfentrazone Dietary Exposure and Risk Assessment DP Number: D384090

PC Code: 129081

____________________________________________________________________________________________

Page 18 of 18

Attachment 4: DEEM-FCID Chronic Exposure Estimates.

U.S. Environmental Protection Agency Ver. 2.00

DEEM-FCID Chronic analysis for SULFENTRAZONE (1994-98 data)

Residue file name: C:\Documents and Settings\jlangsda\My Documents\Chemicals\Sulfentrazone\November 

2010\Sent to Reviewers\129081-chronic-2009-jml__01 DEC 2010.R98

 Adjustment factor #2 used.

Analysis Date 12-01-2010/10:00:17 Residue file dated: 12-01-2010/09:51:00/8

Reference dose (RfD, Chronic) = .1 mg/kg bw/day

===============================================================================

 Total exposure by population subgroup

-------------------------------------------------------------------------------

 Total Exposure

 -----------------------------------

 Population mg/kg Percent of 

 Subgroup body wt/day Rfd 

-------------------------------------- ------------- ---------------

U.S. Population (total) 0.001751 1.8%

U.S. Population (spring season) 0.001760 1.8%

U.S. Population (summer season) 0.001841 1.8%

U.S. Population (autumn season) 0.001701 1.7%

U.S. Population (winter season) 0.001700 1.7%

Northeast region 0.001667 1.7%

Midwest region 0.001810 1.8%

Southern region 0.001696 1.7%

Western region 0.001849 1.8%

Hispanics 0.001922 1.9%

Non-hispanic whites 0.001704 1.7%

Non-hispanic blacks 0.001782 1.8%

Non-hisp/non-white/non-black 0.002025 2.0%

All infants (< 1 year) 0.003117 3.1%

Nursing infants 0.001240 1.2%

Non-nursing infants 0.003829 3.8%

Children 1-6 yrs 0.003430 3.4%

Children 7-12 yrs 0.002286 2.3%

Females 13-19 (not preg or nursing) 0.001519 1.5%

Females 20+ (not preg or nursing) 0.001400 1.4%

Females 13-50 yrs 0.001534 1.5%

Females 13+ (preg/not nursing) 0.001513 1.5%

Females 13+ (nursing) 0.001853 1.9%

Males 13-19 yrs 0.001796 1.8%

Males 20+ yrs 0.001485 1.5%

Seniors 55+ 0.001352 1.4%

Children 1-2 yrs 0.003565 3.6%

Children 3-5 yrs 0.003463 3.5%

Children 6-12 yrs 0.002404 2.4%

Youth 13-19 yrs 0.001660 1.7%

Adults 20-49 yrs 0.001492 1.5%

Adults 50+ yrs 0.001360 1.4%

Females 13-49 yrs 0.001451 1.5%

-------------------------------------------------------------------------------