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EPA REGISTRATION DIVISION COMPANY NOTICE OF FILING FOR 

PESTICIDE PETITIONS PUBLISHED IN THE FEDERAL REGISTER 

EPA Registration Division contact: William Cutchin (703)-305-7990

TEMPLATE:

Huntsman Corp.

IN-10607

EPA has received a pesticide petition (IN-10607) from Huntsman Corp., 8600 

Gosling Rd., The Woodlands, TX 773811 requesting, pursuant to section 408(d) of the 

Federal Food, Drug, and Cosmetic Act (FFDCA), 21 U.S.C. 346a(d), to amend 40 CFR 

part 180 to establish an exemption from the requirement of a tolerance for 2,5-

furandione, polymer with ethenylbenzene, reaction products with polyethylenepolypropylene glycol 2-aminopropyl Me ether, minimum number average molecular 

weight (in amu), 10,000 (CASRN 162568-32-3) under 40 CFR§180.960 when used as an 

inert ingredient surfactant in food use pesticide formulations without limit. 

EPA has determined that the petition contains data or information regarding the 

elements set forth in section 408 (d)(2) of FDDCA; however, EPA has not fully 

evaluated the sufficiency of the submitted data at this time or whether the data supports 

granting of the petition. Additional data may be needed before EPA rules on the petition.

A. Residue Chemistry

1. Plant metabolism. NA-Remove based on the fact that this information is not 

required for the establishment of a tolerance exemption.

2. Analytical method. NA-Remove based on the fact that this information is not 

required for the establishment of a tolerance exemption Insert text.

3. Magnitude of residues. NA-Remove based on the fact that this information is 

not required for the establishment of a tolerance exemption Insert text.

B. Toxicological Profile

1. Acute toxicity. 2,5-furandione, polymer with ethenylbenzene, reaction products 

with polyethylene-polypropylene glycol 2-aminopropyl Me ether conforms to the 

definition of a polymer given in 40 CFR 723.250(b) and meets the following 40 CFR 

723.250 criteria that are used to identify low-risk polymers.
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1a. The polymer is not a cationic polymer nor is it reasonably anticipated to

become a cationic polymer in a natural aquatic environment.

1b. The polymer does contain as an integral part of its composition the atomic

elements carbon, hydrogen, nitrogen and oxygen.

1c. The polymer does not contain as an integral part of its composition, except as 

impurities, any element other than those listed in 40 CFR 723.250(d)(2)(ii).

1d. The polymer is neither designed nor can it be reasonably anticipated to

substantially degrade, decompose, or depolymerize.

1e. The polymer is manufactured or imported from monomers and/or reactants 

that are already included on the TSCA Chemical Substance Inventory.

1f. The polymer is not a water absorbing polymer with a number average

molecular weight (MWn) greater than or equal to 10,000 daltons.

1g. The polymer does not contain fluorine, so 40CFR 723.250(d)(6) does not

apply.

Additionally, the polymer also meets as required the following exemption criteria 

specified in 40 CFR 723.250(e)(2). The polymer's number average MW of 23,817 is 

greater than or equal to 10,000 daltons. The polymer contains less than 2% oligomeric 

material below MW 500 and less than 5% oligomeric material below MW 1,000.

2. Genotoxicty. NA-Remove based on the fact that this polymer meets the 40 CFR 

723.250 criteria that are used to identify low-risk polymers.

3. Reproductive and developmental toxicity. NA-Remove based on the fact that 

this polymer meets the 40 CFR 723.250 criteria that are used to identify low-risk 

polymers.

4. Subchronic toxicity. NA-Remove based on the fact that this polymer meets the 

40 CFR 723.250 criteria that are used to identify low-risk polymers.

5. Chronic toxicity. NA-Remove based on the fact that this polymer meets the 40

CFR 723.250 criteria that are used to identify low-risk polymers.

6. Animal metabolism. NA-Remove based on the fact that this polymer meets the 

40 CFR 723.250 criteria that are used to identify low-risk polymers.

7. Metabolite toxicology. NA-Remove based on the fact that this polymer meets 

the 40 CFR 723.250 criteria that are used to identify low-risk polymers.

8. Endocrine disruption. NA-Remove based on the fact that this polymer meets 

the 40 CFR 723.250 criteria that are used to identify low-risk polymers.

C. Aggregate Exposure

1. Dietary exposure. This polymer meets the 40 CFR 723.250 criteria that are

used to identify low-risk polymers.
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i. Food. This polymer meets the 40 CFR 723.250 criteria that are used to identify 

low-risk polymers.

ii. Drinking water. This polymer meets the 40 CFR 723.250 criteria that are used 

to identify low-risk polymers.

2. Non-dietary exposure. This polymer meets the 40 CFR 723.250 criteria that are

used to identify low-risk polymers.

D. Cumulative Effects

This polymer meets the 40 CFR 723.250 criteria that are used to identify low-risk 

polymers.

E. Safety Determination

1. U.S. population. This polymer meets the 40 CFR 723.250 criteria that are used 

to identify low-risk polymers.

2. Infants and children. This polymer meets the 40 CFR 723.250 criteria that are

used to identify low-risk polymers.

F. International Tolerances

There are no known international tolerances for this polymer.